Vincenzi M, Mercurio FA, Leone M

Sam domains in multiple diseases
Curr Med Chem (ISSN: 0929-8673linking, 1875-533xelectronic), 2018 Oct 9; N/D: N/D-N/D.

Mercurio FA, Pirone L, Di Natale C, Marasco D, Pedone EM, Leone M

Sam domain-based stapled peptides: Structural analysis and interaction studies with the Sam domains from the EphA2 receptor and the lipid phosphatase Ship2
Bioorg Chem (ISSN: 0045-2068linking, 1090-2120electronic), 2018 Oct; 80: 602-610.

Mercurio FA, Scaloni A, Caira S, Leone M

The antimicrobial peptides casocidins I and II: Solution structural studies in water and different membrane-mimetic environments
Peptides (ISSN: 0196-9781linking, 1873-5169electronic), 2018 Sep 19; N/D: N/D-N/D.

Langella E, Buonanno M, Vullo D, Dathan N, Leone M, Supuran C, De Simone G, Monti SM

Biochemical, biophysical and molecular dynamics studies on the proteoglycan-like domain of carbonic anhydrase IX
Cell Mol Life Sci, 2018 Sep; 75: 3283-3296.

Avitabile C, Diaferia C, Della Ventura B, Mercurio FA, Leone M, Roviello V, Saviano M, Velotta R, Morelli G, Accardo A, Romanelli A

Self-Assembling of Fmoc-GC Peptide Nucleic Acid Dimers into Highly Fluorescent Aggregates
Chemistry (ISSN: 1521-3765electronic, 0947-6539linking), 2018 Mar 26; 24(18): 4729-4735.

Mercurio FA, Di Natale C, Pirone L, Marasco D, Calce E, Vincenzi M, Pedone EM, De Luca S, Leone M

Design and analysis of EphA2-SAM peptide ligands: a multi-disciplinary screening approach
Bioorganic Chemistry, 2018; N/D: N/D-N/D.

Buonanno M, Coppola M, Di Lelio I, Molisso D, Leone M, Pennacchio F, Langella E, Rao R, Monti SM

Prosystemin, a prohormone that modulates plant defense barriers, is an intrinsically disordered protein
Protein Sci (ISSN: 1469-896xelectronic, 0961-8368linking), 2018; N/D: N/D-N/D.

Mercurio FA, Di Natale C, Pirone L, Iannitti R, Marasco D, Pedone EM, Palumbo R, Leone M

The Sam-Sam interaction between Ship2 and the EphA2 receptor: design and analysis of peptide inhibitors
SCI REP-UK (ISSN: 2045-2322), 2017 Dec 12; 7(1): 17474-17474.

La Manna S, Lopez-sanz L, Leone M, Brandi P, Scognamiglio PL, Morelli G, Novellino E, Gomez-guerrero C, Marasco D

Structure-activity studies of peptidomimetics based on kinase-inhibitory region of suppressors of cytokine signaling
BIOPOLYMERS (ISSN: 0006-3525), 2017 Nov 20; N/D: N/D-N/D.

Mercurio FA, Costantini S, Di Natale C, Pirone L, Guariniello S, Scognamiglio PL, Marasco D, Pedone EM, Leone M

Structural investigation of a C-terminal EphA2 receptor mutant: Does mutation affect the structure and interaction properties of the Sam domain?
BBA-BIOENERGETICS (ISSN: 0005-2728), 2017 Jun 06; 1865(9): 1095-1104.

Pirone L, Ripoll-rozada J, Leone M, Ronca R, Lombardo F, Fiorentino G, Andersen JF, Pereira PJB, Arcà B, Pedone E

Functional analyses yield detailedinsight into the mechanism of thrombin inhibition by the antihemostatic salivary protein cE5 from Anopheles gambiae
Jbc Papers, 2017 Jun; N/D: N/D-N/D.

La Manna S, Scognamiglio PL, Di Natale C, Leone M, Mercurio FA, Malfitano AM, Cianfarani F, Madonna S, Caravella S, Albanesi C, Novellino E, Marasco D

Characterization of linear mimetic peptides of Interleukin-22 from dissection of protein interfaces
BIOCHIMIE (ISSN: 0300-9084), 2017 May 04; N/D: N/D-N/D.

Diaferia C, Gianolio E, Sibillano T, Mercurio FA, Leone M, Giannini C, Balasco N, Vitagliano L, Morelli G, Accardo A

Cross-beta nanostructures based on dinaphthylalanine Gd-conjugates loaded with doxorubicin
SCI REP-UK (ISSN: 2045-2322), 2017 Mar 22; 7(1): 307-307.

Mercurio FA, Marasco D, Di Natale C, Pirone L, Costantini S, Pedone EM, Leone M

Targeting EphA2-Sam and Its Interactome: Design and Evaluation of Helical Peptides Enriched in Charged Residues
CHEMBIOCHEM (ISSN: 1439-4227), 2016 Nov 17; 17(22): 2179-2188.

Mercurio F, Leone M

The Sam Domain of EphA2 receptor and its relevance to cancer: a novel challenge for drug discovery?
CURR MED CHEM (ISSN: 0929-8673), 2016 Nov 01; N/D: N/D-N/D.

Sinopoli A, Giuffrida A, Tomasello MF, Giuffrida ML, Leone M, Attanasio F, Caraci F, De Bona P, Naletova I, Saviano M, Copani A, Pappalardo G, Rizzarelli E

Ac-LPFFD-Th: A Trehalose-Conjugated Peptidomimetic as a Strong Suppressor of Amyloid-beta Oligomer Formation and Cytotoxicity
CHEMBIOCHEM (ISSN: 1439-4227), 2016 Aug 17; 17(16): 1541-1549.

Scognamiglio PL, Di Natale C, Leone M, Cascella R, Cecchi C, Lirussi L, Antoniali G, Riccardi D, Morelli G, Tell G, Chiti F, Marasco D

Destabilisation, aggregation, toxicity and cytosolic mislocalisation of nucleophosmin regions associated with acute myeloid leukemia
ONCOTARGET (ISSN: 1949-2553), 2016 Aug 1; N/D: N/D-N/D.

Diaferia C, Mercurio FA, Giannini C, Sibillano T, Morelli G, Leone M, Accardo A

Self-assembly of PEGylated tetra-phenylalanine derivatives: structural insights from solution and solid state studies
SCI REP-UK (ISSN: 2045-2322), 2016 May 25; 6: 26638-26638.

Calce E, Mercurio F, Leone M, Saviano M, De Luca S

Eco-friendly microwave-assisted protocol to prepare hyaluronan-fatty acid conjugates and to induce their self-assembly process
CARBOHYD POLYM (ISSN: 0144-8617), 2016 Feb; 143: 84-89.

Calce E, Leone M, Mercurio FA, Monfregola L, De Luca S

Solid-Phase S-Alkylation Promoted by Molecular Sieves
ORG LETT (ISSN: 1523-7060), 2015 Nov 20; 17(22): 5646-5649.

Scudiero O, Nigro E, Cantisani M, Colavita I, Leone M, Mercurio FA, Galdiero M, Pessi A, Daniele A, Salvatore F, Galdiero S

Design and activity of a cyclic mini-beta-defensin analog: a novel antimicrobial tool
INT J NANOMED (ISSN: 1178-2013), 2015 Oct 15; 10: 6523-6539.

Vincenzi M, Accardo A, Costantini S, Scala S, Portella L, Trotta A, Ronga L, Guillon J, Leone M, Colonna G, Rossi F, Tesauro D

Intrinsically disordered amphiphilic peptides as potential targets in drug delivery vehicles
MOL BIOSYST (ISSN: 1742-206X), 2015 Oct 13; 11(11): 2925-2932.

Di Natale C, Scognamiglio PL, Cascella R, Cecchi C, Russo A, Leone M, Penco A, Relini A, Federici L, Di Matteo A, Chiti F, Vitagliano L, Marasco D

Nucleophosmin contains amyloidogenic regions that are able to form toxic aggregates under physiological conditions
The Faseb Journal (ISSN: 1530-6860, 1530-6860electronic), 2015 Sep; 29(9): 3689-3701.

Calce E, Ringhieri P, Mercurio FA, Leone M, Bugatti V, Saviano M, Vittoria V, De Luca S

A biocompatible process to prepare hyaluronan-based material able to self-assemble into stable nano-particles
RSC ADV (ISSN: 2046-2069), 2015; 5(37): 29573-29576.

Vincenzi M, Costantini S, Scala S, Tesauro D, Accardo A, Leone M, Colonna G, Guillon J, Portella L, Trotta AM, Ronga L, Rossi F

Conformational ensembles explored dynamically from disordered peptides targeting chemokine receptor CXCR4
INT J MOL SCI (ISSN: 1422-0067), 2015; 16(6): 12159-12173.

Mercurio FA, Di Natale C, Pirone L, Scognamiglio PL, Marasco D, Pedone EM, Saviano M, Leone M

Peptide Fragments of Odin-Sam1: Conformational Analysis and Interaction Studies with EphA2-Sam
CHEMBIOCHEM (ISSN: 1439-4227), 2015; 16(11): 1629-1636.

Mercurio FA, Scognamiglio PL, Di Natale C, Marasco D, Pellecchia M, Leone M

Cd And Nmr Conformational Studies Of A Peptide Encompassing The Mid Loop Interface Of Ship2-Sam
BIOPOLYMERS (ISSN: 0006-3525), 2014 Nov; 101(11): 1088-1098.

Cantisani M, Finamore E, Mignogna E, Falanga A, Nicoletti GF, Pedone C, Morelli G, Leone M, Galdiero M, Galdiero S

Structural insights into and activity analysis of the antimicrobial peptide myxinidin
ANTIMICROB AGENTS CH (ISSN: 0066-4804), 2014 Sep; 58(9): 5280-5290.

Scognamiglio PL, Di Natale C, Leone M, Poletto M, Vitagliano L, Tell G, Marasco D

G-quadruplex DNA recognition by nucleophosmin: new insights from protein dissection
BBA-BIOENERGETICS (ISSN: 0005-2728), 2014 Jun; 1840(6): 2050-2059.

Leone M, Mercurio FA, Vincenzi M, Accardo A, Ringhieri P, Tesauro D, Carrière F, Rossi F

Conformational Disorder In Phosphopeptides: Solution Studies By Cd And Nmr Techniques
Peptidomics, 2014; 1: 14-21.

Calce E, Leone M, Monfregola L, De Luca S

Lipidated Peptides Via Post-Synthetic Thioalkylation Promoted By Molecular Sieves
AMINO ACIDS (ISSN: 0939-4451), 2014; 46(8): 1899-1905.

Cantisani M, Leone M, Mignogna E, Kampanaraki K, Falanga A, Morelli G, Galdiero M, Galdiero S

Structure-Activity Relations of Myxinidin, an Antibacterial Peptide Derived from the Epidermal Mucus of Hagfish
Antimicrobial Agents And Chemotherapy (ISSN: 0066-4804, 1098-6596), 2013 Nov; 57(11): 5665-5673.

Mercurio FA, Marasco D, Pirone L, Scognamiglio PL, Pedone E, Pellecchia M, Leone M

Heterotypic Sam-Sam Association Between Odin-Sam1 And Arap3-Sam: Binding Affinity And Structural Insights
Chembiochem (ISSN: 1439-4227, 1439-9422, 1439-7633), 2013 Jan 2; 14(1): 100-106.

Calce E, Leone M, Monfregola L, De Luca S

Chemical Modifications Of Peptide Sequences Via S-Alkylation Reaction
Org Lett (ISSN: 1523-7060, 1523-7052, 1523-7052electronic), 2013; 15(20): 5354-5357.

Accardo A, Leone M, Tesauro D, Aufiero R, Bénarouche A, Cavalier JF, Longhi S, Carriere F, Rossi F

Solution conformational features and interfacial properties of an intrinsically disordered peptide coupled to alkyl chains: A new class of peptide amphiphiles
Mol Biosyst (ISSN: 1742-206x), 2013; 9(6): 1401-1410.

Lirussi L, Antoniali G, Vascotto C, D'Ambrosio C, Poletto M, Romanello M, Marasco D, Leone M, Quadrifoglio F, Bhakat KK, Scaloni A, Tell G

Nucleolar accumulation of APE1 depends on charged lysine residues that undergo acetylation upon genotoxic stress and modulate its BER activity in cells
Molecular Biology Of The Cell (ISSN: 1059-1524), 2012 Oct 15; 23(20): 4079-4096.

Monfregola L, Leone M, Calce E,  de Luca S

Postsynthetic modification of peptides via chemoselective N-alkylation of their side chains
Org Lett (ISSN: 1523-7060, 1523-7052, 1523-7052electronic), 2012 Apr 6; 14(7): 1664-1667.

Scarí G, Porta F, Fascio U, Avvakumova S, Dal Santo V, De Simone M, Saviano M, Leone M, Del Gatto A, Pedone C, Zaccaro L

Gold nanoparticles capped by a GC-containing peptide functionalized with an RGD motif for integrin targeting
Bioconjug Chem (ISSN: 1520-4812, 1043-1802, 1520-4812electronic), 2012 Mar 21; 23(3): 340-349.

Mercurio FA, Marasco D, Pirone L, Pedone E, Pellecchia M,  Leone M

Solution Structure of the First Sam Domain of Odin and Binding Studies with the EphA2 Receptor
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2012 Mar 13; 51(10): 2136-2145.

Malgieri G, Zaccaro L, Leone M, Bucci E, Esposito S, Baglivo I, Del Gatto A, Russo L, Scandurra R, Pedone PV, Fattorusso R, Isernia C

Zinc to Cadmium Replacement in the A. thaliana SUPERMAN Cys(2)His(2) Zinc Finger Induces Structural Rearrangements of Typical DNA Base Determinant Positions
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2011 Nov; 95(11): 801-810.

Barile E, Leone M, Barile E, Dahl R, Pellecchia M

Design and NMR Studies of Cyclic Peptides Targeting the N-Terminal Domain of the Protein Tyrosine Phosphatase YopH
Chem Biol Drug Des Chemical Biology And Drug Design (ISSN: 1747-0277, 1747-0285), 2011 Jan; 77(1): 12-19.

Monfregola L, Leone M, Vittoria V, Amodeo P, De Luca S

Chemical modification of pectin: Environmental friendly process for new potential material development
Polym Chem (ISSN: 1759-9954), 2011; 2(4): 800-804.

Leone M, Barile E, Vazquez J, Mei A, Guiney D, Dahl R, Pellecchia M

NMR-based design and evaluation of novel bidentate inhibitors of the protein tyrosine phosphatase YopH
Chem Biol Drug Des Chemical Biology And Drug Design (ISSN: 1747-0277, 1747-0285), 2010 Jul; 76(1): 10-16.

Santelli E, Leone M, Li C, Fukushima T, Preece NE, Olson AJ, Ely KR, Reed JC, Pellecchia M, Liddington RC, Matsuzawa S-I

Structural analysis of Siah1-Siah-interacting protein interactions and insights into the assembly of an E3 ligase multiprotein complex
J Biol Chem Journal Of Biological Chemistry (ISSN: 0021-9258, 1083-351x), 2005 Oct 7; 280(40): 34278-34287.

Leone M, Di Lello P, Ohlenschläger O, Pedone E, Bartolucci S, Rossi M, Di Blasio B, Pedone C, Saviano M, Isernia C, Fattorusso R

Solution structure and backbone dynamics of the K18G/R82E Alicyclobacillus acidocaldarius thioredoxin mutant: A molecular analysis of its reduced thermal stability
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2004 May 25; 43(20): 6043-6058.

Isernia C, Bucci E, Leone M, Zaccaro L, Di Lello P, Digilio G, Esposito S, Saviano M, Di Blasio B, Pedone C, Pedone PV, Fattorusso R

NMR structure of the single QALGGH zinc finger domain from the Arabidopsis thaliana SUPERMAN protein
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2003 Mar 3; 4(2-3): 171-180.

Oliva R, Leone M, Falcigno L, D'Auria G, Dettin M, Scarinci C, Di Bello C, Paolillo L

Structural investigation of the HIV-1 envelope glycoprotein gp160 cleavage site
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2002 Mar 15; 8(6): 1467-1473.