Parole chiave: Formic Acid Derivative, Oligopeptide, T Butyloxycarbonyl Group, T-Butyloxycarbonyl Group, Article, Protein Conformation, Solution And Solubility, Formic Acid Esters, Support, Non-U.S. Gov, Non-U. S. Gov,
Boc-L-Asu-L-Ala-Gly-OMe crystallizes in the monoclinic space group P2(1) with cell dimensions a = 14.315 (3) A, b = 9.280 (2) A, c = 14.358(3) A, beta = 103.63(1) A, V= 1853.4 (9) A3, with two molecules in the asymmetric unit. The conformation of the two molecules is characterized by a type II' beta-bend, similar to that predicted earlier by potential energy calculations, stabilized by an intramolecular hydrogen bond. I.r. and 1H-n.m.r. data show that the folded conformation is also stable in chloroform solution.