Esposito L, Donnarumma F, Ruggiero A, Leone S, Vitagliano L, Picone D

Structure, stability and aggregation propensity of a Ribonuclease A-Onconase chimera
Int J Biol Macromol (ISSN: 0141-8130linking, 1879-0003electronic), 2019 Jul 15; 133: 1125-1133.

Ruggiero A, Garcia-ortega L, Moreira M, Ragucci S, Landi N, Di Maro A, Berisio R

Binding and enzymatic properties of Ageritin, a fungal ribotoxin with novel zinc-dependent function
Int J Biol Macromol (ISSN: 0141-8130linking), 2019 Jun 18; 136: 625-631.

Calvanese L, Squeglia F, Romano M, D'Auria G, Falcigno L, Berisio R

Structural and dynamic studies provide insights into specificity and allosteric regulation of Ribonuclease AS, a key enzyme in mycobacterial virulence
J Biomol Struct Dyn (ISSN: 0739-1102linking), 2019; N/D: 1-19.

Ruggiero A, Garcia-ortega L, Ragucci S, Russo R, Landi N, Berisio R, Di Maro A

Structural and enzymatic properties of Ageritin, a novel metal-dependent ribotoxin-like protein with antitumor activity
Bba-Gen Subjects (ISSN: 1872-8006electronic, 0304-4165linking, 0304-4165print), 2018 Sep 18; 1862(12): 2888-2894.

Smaldone G, Berisio R, Balasco N, D'Auria S, Vitagliano L, Ruggiero A

Domain swapping dissection in Thermotoga maritima arginine binding protein: How structural flexibility may compensate destabilization
Biochim Biophys Acta Proteins Proteom (ISSN: 1570-9639print, 1570-9639linking), 2018 May 31; 1866(9): 952-962.

Smaldone G, Vigorita M, Ruggiero A, Balasco N, Dattelbaum JD, D'Auria S, Del Vecchio P, Graziano G, Vitagliano L

Proline 235 plays a key role in the regulation of the oligomeric states of Thermotoga maritima Arginine Binding Protein
Bba-Bioenergetics (ISSN: 0005-2728, 0006-3002print), 2016 Jul; 1864(7): 814-824.

Messori L, Marzo T, Merlino A

Interactions of carboplatin and oxaliplatin with proteins: Insights from X-ray structures and mass spectrometry studies of their ribonuclease A adducts
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2015; N/D: N/D-N/D.

Ruggiero A, Dattelbaum JD, Staiano M, Berisio R, D'Auria S, Vitagliano L

A loose domain swapping organization confers a remarkable stability to the dimeric structure of the arginine binding protein from Thermotoga maritima
Plosone (ISSN: 1932-6203, 1932-6203electronic), 2014 May 15; 9(5): e96560-e96560.

Romanò MF, Van De Weerd R, Brouwer FCC, Roviello GN, Lacroix R, Sparrius M, Van Den Brink-van Stempvoort G, Maaskant JJ, Van Der Sar AM, Appelmelk BJ, Geurtsen JJ, Berisio R

Structure and function of RNase AS, a polyadenylate-specific exoribonuclease affecting mycobacterial virulence in vivo
Structure (ISSN: 0969-2126, 1878-4186), 2014 May 6; 22(5): 719-730.

Testi S, Peluso S, Fabrizi GM, Antenora A, Russo CV, Pappata S, Padovani A, Ferrarini M, Filla A

A novel PSEN1 mutation in a patient with sporadic early-onset Alzheimer's disease and prominent cerebellar ataxia
J Alzheimers Dis (ISSN: 1387-2877), 2014; 41(3): 709-714.

Messori L, Scaletti F, Massai L, Cinellu MA, Russo Krauss I, Di Martino G, Vergara A, Paduano L, Merlino A

Interactions of gold-based drugs with proteins: crystal structure of the adduct formed between ribonuclease A and a cytotoxic gold(III) compound
Metallomics (ISSN: 1756-5901, 1756-591x), 2014; 6(2): 233-236.

Sica F, Pica A, Merlino A, Russo Krauss I, Ercole C, Picone D

The multiple forms of bovine seminal ribonuclease: Structure and stability of a C-terminal swapped dimer
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 2013 Nov 29; 587(23): 3755-3762.

Pica A, Merlino A, Buell AK, Knowles TJ, Pizzo E, D'Alessio G, Sica F, Mazzarella L

Three-dimensional domain swapping and supramolecular protein assembly: insights from the X-ray structure of a dimeric swapped variant of human pancreatic RNase
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2013 Oct; 69: 2116-2123.

Balasco N, Esposito L, De Simone A, Vitagliano L

Role of loops connecting secondary structure elements in the stabilization of proteins isolated from thermophilic organisms
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic), 2013 Jul; 22(7): 1016-1023.

Balasco N, Esposito L, De Simone A, Vitagliano L

FOR the RECORD: Role of loops connecting secondary structure elements in the stabilization of proteins isolated from thermophilic organisms
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic), 2013; 22(7): 1016-1023.

Merlino A, Picone D, Ercole C, Balsamo A, Sica F

Chain termini cross-talk in the swapping process of bovine pancreatic ribonuclease
Biochimie (ISSN: 0300-9084, 1638-6183, 1638-6183electronic), 2012 May; 94(5): 1108-1118.

Folgiero V, Di Carlo SE, Bossi G, Spugnini E, Di Benedetto A, Bon G, Milella M, Fabi A, Accardo A, Morelli G, Mottolese M, Falcioni R

Inhibition of p85, the non-catalytic subunit of phosphatidylinositol 3-kinase, exerts potent antitumor activity in human breast cancer cells
Cell Death & (ISSN: 2041-4889, 2041-4889electronic), 2012; 3(12): N/D-N/D.

D'Errico G, Ercole C, Lista M, Pizzo E, Falanga A, Galdiero S, Spadaccini R, Picone D

Enforcing the positive charge of N-termini enhances membrane interaction and antitumor activity of bovine seminal ribonuclease
Bba-Mol Basis Dis (ISSN: 0005-2736, 0006-3002, 0925-4439), 2011 Dec; 1808(12): 3007-3015.

Merlino A, Russo Krauss I, Perillo M, Mattia CA, Ercole C, Picone D, Vergara A, Sica F

Toward an Antitumor Form of Bovine Pancreatic Ribonuclease: The Crystal Structure of Three Noncovalent Dimeric Mutants
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2009 Dec; 91(12): 1029-1037.

Merlino A, Avella G, Di Gaetano S, Arciello A, Piccoli R, Mazzarella L, Sica F

Structural features for the mechanism of antitumor action of a dimeric human pancreatic ribonuclease variant
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic, 0961-8368linking), 2009 Jan; 18(1): 50-57.

Merlino A, Ercole C, Picone D, Pizzo E, Mazzarella L, Sica F

The buried diversity of bovine seminal ribonuclease: Shape and cytotoxicity of the swapped non-covalent form of the enzyme
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2008 Feb 15; 376(2): 427-437.

Serrano CM, Allegri RF, Caramelli P, Taragano FE, Camera L

Mild cognitive impairment. Survey of attitudes of specialists and general physicians
Medicina (ISSN: 0025-7680), 2007; 67(1): 19-25.

Bucci E, Vitagliano L, Barone R, Sorrentino S, D'Alessio G, Graziano G

On the thermal stability of the two dimeric forms of ribonuclease
Biophys Chem (ISSN: 0301-4622, 0301-4622linking), 2005 Jul 1; 116(2): 89-95.

Merlino A, Mazzarella L, Carannante A, Di Fiore A, Di Donato A, Notomista E, Sica F

The importance of dynamic effects on the enzyme activity: X-ray structure and molecular dynamics of onconase mutants
J Biol Chem (ISSN: 0021-9258, 1083-351x), 2005 May 6; 280(18): 17953-17960.

Picone D, Di Fiore A, Ercole C, Franzese M, Sica F, Tomaselli S, Mazzarella L

The role of the hinge loop in domain swapping - The special case of bovine seminal ribonuclease
J Biol Chem (ISSN: 0021-9258, 1083-351x), 2005 Apr 8; 280(14): 13771-13778.

Esposito L, Daggett V

Insight into ribonuclease A domain swapping by molecular dynamics unfolding simulations
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2005 Mar 8; 44(9): 3358-3368.

De Simone G, Menchise V, Alterio V, Mandrich L, Rossi M, Manco G, Pedone C

The crystal structure of an EST2 mutant unveils structural insights on the H group of the carboxylesterase/lipase family
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2004 Oct 8; 343(1): 137-146.

Merlino A, Vitagliano L, Sica F, Zagari A, Mazzarella L

Population shift vs induced fit: The case of bovine seminal ribonuclease swapping dimer
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2004 Apr 15; 73(6): 689-695.

Merlino A, Vitagliano L, Ceruso MA, Mazzarella L

Dynamic properties of the N-terminal swapped dimer of ribonuclease
Biophysical Journal (ISSN: 0006-3495, 1542-0086), 2004 Apr; 86(4): 2383-2391.

Berisio R, Sica F, De Lorenzo C, Di Fiore A, Piccoli R, Zagari A, Mazzarella L

Crystal Structure Of The Dimeric Un-Swapped Form Of Bovine Seminal Ribonuclease
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 2003 Nov 6; 554(1-2): 105-110.

Merlino A, Vitagliano L, Ceruso MA, Mazzarella L

Subtle functional collective motions in pancreatic-like ribonucleases: From ribonuclease A to angiogenin
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2003 Oct 1; 53(1): 101-110.

Sica F, Di Fiore A, Zagari A, Mazzarella L

The unswapped chain of bovine seminal ribonuclease: Crystal structure of the free and liganded monomeric derivative
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2003 Sep 1; 52(2): 263-271.

Merlino A, Vitagliano L, Ceruso M, Di Nola A, Mazzarella L

Global and local motions in ribonuclease A: A molecular dynamics study
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2002 Nov 15; 65(4): 274-283.

Berisio R, Sica F, Lamzin VS, Wilson KS, Zagari A, Mazzarella L

Atomic resolution structures of ribonuclease A at six pH values
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2002; 58(3): 441-450.

Orru S, Vitagliano L, Esposito L, Mazzarella L, Marino G, Ruoppolo M

Effect of deamidation on folding of ribonuclease
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic), 2000 Dec; 9(12): 2577-2582.

Esposito L, Vitagliano L, Zagari A, Mazzarella L

Experimental evidence for the correlation of bond distances in peptide groups detected in ultrahigh-resolution protein structures
Protein Eng (ISSN: 0269-2139, 0269-2139print, 0269-2139linking), 2000 Dec; 13(12): 825-828.

Vitagliano L, Merlino A, Zagari A, Mazzarella L

Productive and nonproductive binding to ribonuclease A: X-ray structure of two complexes with uridylyl(2 ', 5 ')guanosine
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic), 2000 Jun; 9(6): 1217-1225.

Esposito L, Vitagliano L, Sica F, Sorrentino G, Zagari A, Mazzarella L

The ultrahigh resolution crystal structure of ribonuclease A containing an isoaspartyl residue: Hydration and sterochemical analysis
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2000 Mar 31; 297(3): 713-732.

ZagariA, Berisio R, Merlino A, Sica F, Vitagliano L, Mazzarella L

Reversible domain motions induced by substrate binding in ribonuclease
Acta Crystallographica Section A, 2000; 56: 263-263.

Vitagliano L, Adinolfi S, Sica F, Merlino A, Zagari A, Mazzarella L

A potential allosteric subsite generated by domain swapping in bovine seminal ribonuclease
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 1999 Oct 29; 293(3): 569-577.

Berisio R, Lamzin VS, Sica F, Wilson KS, Zagari A, Mazzarella L

Protein titration in the crystal state
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 1999 Oct 1; 292(4): 845-854.

Sica F, Adinolfi S, Berisio R, De Lorenzo C, Mazzarella L, Piccoli R, Vitagliano L, Zagari A

Crystallization of multiple forms of bovine seminal ribonuclease in the liganded and unliganded state
J Cryst Growth (ISSN: 0022-0248), 1999; 196(2-4): 305-312.

Vitagliano L, Adinolfi S, Riccio A, Sica F, Zagari A, Mazzarella L

Binding of a substrate analog to a domain swapping protein: X-ray structure of the complex of bovine seminal ribonuclease with uridylyl(2 ', 5 ')adenosine
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic), 1998 Sep; 7(8): 1691-1699.

Adinolfi S, Piccoli R, Sica F, Mazzarella L

BS-RNase tetramers: An example of domain-swapped oligomers
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 1996 Dec 2; 398(2-3): 326-332.

Capasso S, Di Donato A, Esposito L, Sica F, Sorrentino G, Vitagliano L, Zagari A, Mazzarella L

Deamidation in proteins: The crystal structure of bovine pancreatic ribonuclease with an isoaspartyl residue at position 67
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 1996; 257(3): 492-496.

Cucinotta V, Mangano A, Nobile G, Santoro AM, Vecchio G

New platinum(II) complexes of β-cyclodextrin diamine derivatives and their antitumor activity
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 1993 Nov 15; 52(3): 183-190.