Quantitation of left ventricular asynchrony on radionuclide angiography phase images(144 visite)(PDF privato114 visite) Alfano B, Betocchi S, Pace L, Perrone-Filardi P, Chiariello M, Salvatore M
Parole chiave: Asynchrony, Phase Images, Radionuclide Angiography, Erythrocyte Tc 99m, Radioisotope, Technetium 99m, Adult, Article, Female, Heart Left Ventricle Asynergy, Human, Major Clinical Study, Methodology, Scintiangiography, Coronary Disease, Gated Blood-Pool Imaging, Middle Age, Reproducibility Of Results, Roc Curve, Support, Non-U.S. Gov, Ventricular Function, Non-U. S. Gov, Coronary Disease Radionuclide Imaging, Gated Blood-Pool Imaging Methods, Left Physiology,
Affiliazioni:
Department of Radiology-Nuclear Medicine and Department of Medicine-Cardiology, University of Naples 2nd School of Medicine, Naples, Italy
Riferimenti:
Non disponibile.
Quantitation of left ventricular (LV) asynchrony is relevant in clinical cardiology, as well as in evaluating LV mechanical properties. Radionuclide angiography (RA) phase images are extensively used, and asynchrony is usually assessed by computing the standard deviation of phase angle distribution (SD). However, SD is dependent on count statistics and does not take into account the spatial distribution of asynchrony. In this study a new index to evaluate asynchrony on phase images is presented (differential uniformity parameter, DUP). DUP is based on the frequency analysis of phase images. Diagnostic accuracy and reproducibility of either SD or DUP were tested. Reproducibility was evaluated in 15 patients studied by RA twice within a few minutes. DUP showed a better reproducibility than SD. Diagnostic accuracy was estimated in 84 patients, divided into four subgroups on the basis of coronary arteriography and contrast ventriculography findings: (a) 25 control subjects, (b) 16 patients with coronary artery disease (CAD) and normal LV wall motion, (c) 23 patients with CAD and LV hypokinesia and (d) 20 patients with CAD and LV dyskinesia. Relative diagnostic ability was assessed by comparing the areas under receiver-operating characteristic curves. DUP's area was larger than SD's when group D was tested against all the other groups (DUP's area=87%±5%, SD's area=76%±7%;P
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Hesse B, Tagil K, Cuocolo A, Anagnostopoulos C, Bardies M, Bax J, Bengel F, Busemann Sokole E, Davies G, Dondi M, Edenbrandt L, Franken P, Kjaer A, Knuuti J, Lassmann M, Ljungberg M, Marcassa C, Marie PY, Mckiddie F, O'connor M, Prvuolovich E, Underwood R * 3. 0 T perfusion MR imaging(308 visite) Rivista Di Neuroradiologia (ISSN: 1120-9976), 2004; 17(6): 807-812. Impact Factor:0.023 DettagliEsporta in BibTeXEsporta in EndNote
202 Records (194 escludendo Abstract e Conferenze). Impact factor totale: 592.013 (573.829 escludendo Abstract e Conferenze). Impact factor a 5 anni totale: 719.826 (701.671 escludendo Abstract e Conferenze).
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