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MYOCARDIAL VIABILITY INDEX IN CHRONIC CORONARY-ARTERY DISEASE - TECHNETIUM-99M-METHOXY ISOBUTYL ISONITRILE REDISTRIBUTION (86 visite)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1995 Nov; 36(11): 1953-1960.
Tipo di articolo: Journal Article,
Impact factor: 3.491
Impact factor a 5 anni: 5.331
Parole chiave: Functional Recovery, Left Ventricular Dysfunction, Technetium-99m-Sestamibi, Thallium-201, Methoxy Isobutyl Isonitrile Technetium Tc 99m, Thallium 201, Adult, Article, Clinical Article, Coronary Artery Disease, Diagnostic Imaging, Echocardiography, Female, Heart Ejection Fraction, Heart Left Ventricle Failure, Heart Left Ventricle Function, Heart Muscle, Heart Muscle Revascularization, Human, Priority Journal, Comparative Study, Coronary Disease, Follow-Up Studies, Middle Age, Myocardial Revascularization, Prospective Studies, Technetium Tc 99m Sestamibi, Thallium Radioisotopes, Time Factors, Tomography, Emission-Computed, Single-Photon,
The purpose of this study was to evaluate whether an additional redistribution image after a rest (TC)-T-99m-MIBI injection enhances detection of viable myocardium and predicts functional recovery after coronary revascularization in patients with chronic coronary artery disease (CAD). Methods: Thirty-one patients (29 men, mean age 55 +/- 10 yr) with proven CAD and left ventricular (LV) dysfunction (ejection fraction 39% +/- 9%) underwent resting Tc-99m-MIBI tomography with initial (1 hr) and delayed (5 hr) images. Within 1 wk of MIBI imaging, all patients underwent rest-redistribution (TI)-T-201 imaging. Eight patients also underwent two-dimensional echocardiography before and 5 +/- 3 mo after coronary revascularization. Results: On the initial Tc-99m-MIBI images, 302 myocardial segments were normal, 183 showed moderate and 197 severe reduction of tracer uptake. Of these 197 segments, 47 (24%) demonstrated increased tracer uptake (greater than or equal to 10% versus initial) on delayed images (from 43% +/- 8% to 60% +/- 8%, p
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