ENHANCED DETECTION OF VIABLE MYOCARDIUM BY TECHNETIUM-99M-MIBI IMAGING AFTER NITRATE ADMINISTRATION IN CHRONIC CORONARY-ARTERY DISEASE(195 views visite) Maurea S, Cuocolo A, Soricelli A, Castelli L, Nappi A, Squame F, Imbriaco M, Trimarco B, Salvatore M
Affiliations Affiliazioni: via Raffaele De Cesare 7, 80132 Napoli, Italy
References Riferimenti: Not available. Non disponibili.
ENHANCED DETECTION OF VIABLE MYOCARDIUM BY TECHNETIUM-99M-MIBI IMAGING AFTER NITRATE ADMINISTRATION IN CHRONIC CORONARY-ARTERY DISEASE
The aim of this study was to assess whether nitrate administration improves the imaging capabilities of (TC)-T-99m-MIBI tomography in detecting viable myocardium in coronary artery disease (CAD). Methods: Thirty-one patients with angiographically proven CAD and chronic LV dysfunction (ejection fraction 39% +/- 9%) underwent two Tc-99m-MIBI studies on separate days: one under rest conditions and the other after nitroglycerine (0.005 mg/kg per os) administration. Within 1 wk, all patients also underwent rest-redistribution (TI)-T-201 imaging. Eight patients were also studied by echocardiography before and 5 +/- 3 mo after coronary revascularization. Results: On resting Tc-99m-MIBI images, 302 segments had normal uptake, 183 segments had moderately reduced uptake and 197 had severely reduced uptake. Of the segments with severely reduced uptake, 54 (27%) had increased uptake after nitroglycerine and were viable on (TI)-T-201 images. Of the 143 (73%) segments with severely reduced Tc-99m-MIBI uptake and no change after nitroglycerine, 81% were nonviable on (TI)-T-201 images. In the eight patients studied before and after revascularization, 87% of segments with reversible Tc-99m-MIBI defects and abnormal LV function demonstrated functional recovery after revascularization, whereas 89% of segments with irreversible Tc-99m-MIBI defects did not. Conclusion: In patients with chronic ischemic LV dysfunction, nitrate administration improved the detection of severely hypoperfused but still viable myocardium on (TC)-T-99m-MIBI images.
ENHANCED DETECTION OF VIABLE MYOCARDIUM BY TECHNETIUM-99M-MIBI IMAGING AFTER NITRATE ADMINISTRATION IN CHRONIC CORONARY-ARTERY DISEASE
Hesse B, Tagil K, Cuocolo A, Anagnostopoulos C, Bardies M, Bax J, Bengel F, Busemann Sokole E, Davies G, Dondi M, Edenbrandt L, Franken P, Kjaer A, Knuuti J, Lassmann M, Ljungberg M, Marcassa C, Marie PY, Mckiddie F, O'connor M, Prvuolovich E, Underwood R * 3. 0 T perfusion MR imaging(535 visite) Rivista Di Neuroradiologia (ISSN: 1120-9976), 2004; 17(6): 807-812. Impact Factor:0.023 DettagliEsporta in BibTeXEsporta in EndNote
227 Records (190 escludendo Abstract e Conferenze). Impact factor totale: 675.631 (536.83 escludendo Abstract e Conferenze). Impact factor a 5 anni totale: 786.941 (624.182 escludendo Abstract e Conferenze).
Last modified by Ultima modifica di Marco Comerci on in data Sunday 12 July 2020, 13:15:15 195 views visite. Last view on Ultima visita in data Friday 18 December 2020, 11:48:26