Multislice CT with single-phase technique in patients with suspected pancreatic cancer(204 views visite) Imbriaco M, Smeraldo D, Liuzzi R, Carrillo F, Cacace G, Vecchione D, Diglio A, Salvatore M
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 2006 Mar; 111(2): 159-166.
Dipartimento di Scienze Biomorfologiche e Funzionali, UniversitÀ degli Studi di Napoli Federico II, Napoli, Italy Via Posillipo 196, I-80123 Napoli, Italy
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O'Malley, M. E., Boland, G. W., Wood, B. J., Adenocarcinoma of the head of the pancreas: Determination of surgical unresectability with thin-section pancreatic-phase helical CT (1999) AJR Am J Roentgenol, 173, pp. 1513-1518
(1998) Cancer Facts and Figures, , American Cancer Society, Atlanta
Choi, B. I., Chung, M. J., Han, J. K., Yoon, Y. B., Detection of pancreatic adenocarcinoma: Relative value of arterial and late phases of spiral CT (1997) Abdom Imaging, 22, pp. 199-203
Lu, D. S., Vedantham, S., Krasny, R. M., Two phase helical CT for pancreatic tumors: Pancreatic versus hepatic phase enhancement of tumor, pancreas and vascular structures (1996) Radiology, 199, pp. 697-701
Diehl, S. J., Lehmann, K. J., Sadick, M., Pancreatic cancer: Value of dual-phase helical CT in assessing resectability (1998) Radiology, 206, pp. 373-378
Keogan, M. T., McDermott, V. G., Paulson, E. K., Pancreatic malignancy: Effect of dual phase in tumor detection and vascular opacification (1997) Radiology, 205, pp. 513-518
McNulty, N. J., Francis, I. R., Platt, J. F., Multi-detector row helical CT of the pancreas: Effect of contrast enhanced multiphasic imaging on enhancement of the pancreas, peripancreatic vasculature, and pancreatic adenocarcinoma (2001) Radiology, 220, pp. 97-102
Fletcher, J. G., Wiersema, M. J., Farrell, M. A., Pancreatic malignancy: Value of arterial, pancreatic, and hepatic phase imaging with multi-detector row CT (2003) Radiology, 229, pp. 81-90
Prokesch, R. W., Chow, L. C., Beaulieu, C. F., Local staging of pancreatic carcinoma with multi-detector row CT: Use of curved planar reformations-initial experience (2002) Radiology, 225, pp. 759-765
Zeman, R. K., Cooper, C., Zeiberg, A. S., TNM staging of pancreatic carcinoma using helical CT (1997) AJR Am J Roentgenol, 169, pp. 459-464
Metz, C. E., Basic principles of ROC analysis (1978) Semin Nucl Med, 8, pp. 283-298
Metz, C. E., Some practical issues of experimental design and data analysis in radiological ROC studies (1989) Invest Radiol, 24, pp. 34-245
Megibow, A. J., Pancreatic adenocarcinoma: Designing the examination to evaluate the clinical questions (1992) Radiology, 183, pp. 297-303
Tublin, M. E., Tessler, F. N., Cheng, S. L., Effect of injection rate of contrast medium on pancreatic and hepatic helical CT (1999) Radiology, 210, pp. 97-101
Multislice CT with single-phase technique in patients with suspected pancreatic cancer
Purpose. The purpose of this study was to evaluate the role of multislice computed tomography (MSCT) with a single-phase technique in patients with suspected pancreatic cancer (PC). Materials and methods. Seventy-eight patients underwent MSCT with the following technical parameters: collimation: 4x1 mm; pitch 1; 120 kVp; 260 mAs. The pre-contrast scan was followed by a single acquisition phase in the caudocranial direction from the inferior hepatic margin to the diaphragm with a 60-s delay after IV administration of 150 ml of iodinated contrast material at a rate of 3 ml/s. Two radiologists assessed the single images independently. Receiver operating characteristics (ROC) curves were obtained for each of the two observers. Results. The final diagnosis was pancreatic cancer in 46 cases and chronic pancreatitis in 32 cases. Areas under the curve (Az) for diagnosis and evaluation of disease resectability were 0.97 and 0.93 for the first observer (p=ns), and 0.97 and 0.90 for the second observer (p=ns). The mean difference in tissue attenuation values between the cancer and normal pancreas was 72±3 Hounsfield units (HU). No statistically significant differences were observed in the degree of opacification between the peripancreatic arteries and veins. Conclusions. MSCT with a single-phase technique is an accurate and reproducible method for diagnosis and evaluation of disease resectability in patients with suspected PC, ensuring optimal tumour-to-pancreas contrast and maximal opacification of the main peripancreatic arterial and venous structures.
Multislice CT with single-phase technique in patients with suspected pancreatic cancer
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