Cerebral blood flow in spinocerebellar degenerations: a single photon emission tomography study in 28 patients(101 visite) De Michele G, Mainenti PP, Soricelli A, Di Salle F, Salvatore E, Longobardi MR, Postiglione A, Salvatore M, Filla A
Clinica Neurologica, Università Federico II, via S. Pansini 5, I-80131 Napoli, Italy Department of Nuclear Medicine, Federico II University, Naples, Italy Department of Radiology, Federico II University, Naples, Italy Department of Internal Medicine, Federico II University, Naples, Italy
Riferimenti:
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Ormerod, I.E.C., Harding, A.E., Miller, D.H., Johnson, G., MacManus, D., Du Boulay, E.P.G.H., Kendall, B.E., McDonald, W.I., Magnetic resonance imaging in degenerative ataxic disorders (1994) J Neurol Neurosurg Psychiatry, 57, pp. 51-57
Sun, X., Tanaka, M., Kondo, S., Hirai, S., Ishihara, T., Reduced cerebellar blood flow and oxygen metabolism in spinocerebellar degeneration: A combined PET and MRI study (1994) J Neurol, 241, pp. 295-300
Botez, M. I., L veill, J., Lambert, R., Botez, T., Single photon emission tomography (SPECT) in cerebellar disease: Cerebello-cerebral diaschisis (1991) Eur Neurol, 31, pp. 405-41
D rr, A., Brice, A., Genetics of movement disorders (1996) Curr Opin Neurol, 9, pp. 290-297
Greenfield, J. G., (1954) The Spino-cerebellar Degenerations, , Blackwell, Oxford
Harding, A. E., "Idiopathic" late onset cerebellar ataxia (1981) J Neurol Sci, 51, pp. 259-271
Harding, A. E., The clinical features and classification of the late onset autosomal dominant cerebellar ataxias. A study of eleven families, including descendants of "the Drew family of Walworth" (1982) Brain, 105, pp. 1-28
Harding, A. E., Classification of the hereditary ataxias and paraplegias (1983) Lancet, 1, pp. 1151-1155
Ormerod, I. E. C., Harding, A. E., Miller, D. H., Johnson, G., MacManus, D., Du Boulay, E. P. G. H., Kendall, B. E., McDonald, W. I., Magnetic resonance imaging in degenerative ataxic disorders (1994) J Neurol Neurosurg Psychiatry, 57, pp. 51-57
We used single photon emission tomography to study regional cerebral perfusion in patients with different forms of spinocerebellar degeneration: 6 patients with Friedreich's ataxia (FA), 6 with early-onset cerebellar ataxia with retained tendon reflexes (EOCA), 5 with autosomal dominant cerebellar ataxia type 1 (ADCA I) and 11 with idiopathic late-onset cerebellar ataxia (ILOCA). The results were related to clinical and magnetic resonance imaging (MRI) findings. Cerebellar hypoperfusion was constant in ADCA I and frequent in patients with other spinocerebellar degenerations. Brain stem hypoperfusion was constant in ADCA I, frequent in ILOCA patients with pontocerebellar atrophy and absent in FA and EOCA. FA and EOCA often showed a reduction in the parietotemporal cortex blood flow, which was not related to cortical atrophy. ILOCA patients had an asymmetric pattern in the temporal areas with decreased blood flow in the right side only. Caudate hypoperfusion was found in ADCA I patients. Cerebral atrophy did not account for changes in regional blood flow, which probably indicate early involvement of cerebral structures.
Hesse B, Tagil K, Cuocolo A, Anagnostopoulos C, Bardies M, Bax J, Bengel F, Busemann Sokole E, Davies G, Dondi M, Edenbrandt L, Franken P, Kjaer A, Knuuti J, Lassmann M, Ljungberg M, Marcassa C, Marie PY, Mckiddie F, O'connor M, Prvuolovich E, Underwood R * 3. 0 T perfusion MR imaging(143 visite) Rivista Di Neuroradiologia (ISSN: 1120-9976), 2004; 17(6): 807-812. Impact Factor:0.023 DettagliEsporta in BibTeXEsporta in EndNote
61 Records (49 escludendo Abstract e Conferenze). Impact factor totale: 217.145 (178.703 escludendo Abstract e Conferenze). Impact factor a 5 anni totale: 242.313 (199.038 escludendo Abstract e Conferenze).
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