The different role of Cu++ and Zn++ ions in affecting the interaction of prion peptide PrP106-126 with model membranes
CNR Ibb | back to homepage
▲NavBar
Ricerca avanzata▼
Contiene: [X]      Estesa     Autori: [X]  Tipo di lavoro: [X]   Data iniziale: Data finale: [X]      Sede: Affiliazione IBB     
    
[Pulisci modulo]


The different role of Cu++ and Zn++ ions in affecting the interaction of prion peptide PrP106-126 with model membranes (100 visite)

Grasso D, Milardi D, La Rosa C, Rizzarelli E

Chem Commun (ISSN: 1359-7345, 1364-548x, 1364-548xelectronic), 2004 Jan 21; 10(2): 246-247.



Tipo di articolo: Journal Article, Research Support, Non-U. S. Gov'T,

Impact factor: 3.997, Impact factor a 5 anni: 6.485

Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-1642561827&partnerID=40&md5=06eb24a9e5cc8e6be8059d5bbc39c5ed

Parole chiave: 3 Dipalmitoylglycero 3 Phosphocholine, Copper Ion, Glycerol Derivative, Palmitoleic Acid, Peptide, Phosphorylcholine, Prion Protein, Prp 106-126 Protein, Unclassified Drug, Zinc Ion, Article, Differential Scanning Calorimetry, Experimental Test, Ion Transport, Membrane Permeability, Molecular Dynamics, Molecular Interaction, Molecular Model, 2-Dipalmitoylphosphatidylcholine, Chemistry, Cations, Divalent, Gels, Membrane Lipids, Artificial, Peptide Fragments, Temperature,

Affiliazioni:

*** IBB - CNR ***
Dipartimento di Scienze Chimiche, Università di Catania, Viale Andrea Doria, 6 95125 Catania, Italy
Ist. Biostrutture e Bioimmagini CNR, Sezione di Catania Viale A, Doria 6, 95125 Catania, Italy


Riferimenti:

Gajdusek, D.C., Gibbs, C.J., Alpers, M., (1966) Nature, 209, p. 79

Clinton, J., Forsyth, C., Royston, M.C., Roberts, G.W., (1993) Neuroreport, 4, p. 65

Fraser, H., (1993) Br. Med. Bull., 49, p. 792

Jeffrey, M., Goodsir, C.M., Bruce, M.E., McBride, P.A., Farquhar, C., (1994) Neuropathol. Appl. Neurobiol., 20, p. 535

Prusiner, S.B., (1998) Proc. Natl. Acad. Sci. USA, 95, p. 13363

Prusiner, S.B., (1989) Annu. Rev. Microbiol., 43, p. 345

Oesch, B., Westaway, D., Walchli, M., McKinley, M.P., Kent, S.B., Aebersold, R., Barry, R.A., Weissmann, C., (1985) Cell, 40, p. 735

Cherebro, B., Race, R., Wehrly, K., Nishio, J., Bloom, M., Lechner, D., Bergstrom, S., Haase, A., (1985) Nature, 315, p. 331

Basler, K., Oesch, B., Scott, M., Westaway, D., Walchli, M., Groth, D.F., McKinley, M.P., Weissmann, C., Cell, 46, p. 417

Caughey, B., Raymond, G.J., (1991) J. Biol. Chem., 266, p. 18217

Stahl, N., Baldwin, M.A., Teplow, D.B., Hood, L., Gibson, B.W., Burlingame, A.L., Prusiner, S.B., (1993) Biochemistry, 32, p. 1991

Bolton, D.C., McKinley, M.P., Prusiner, S.B., (1982) Science, 218, p. 1309

McKinley, M.P., Bolton, D.C., Prusiner, S.B., (1983) Cell, 35, p. 57

De Armond, S.J., McKinley, M.P., Barry, R.A., Braunfeld, M.B., McColloch, J.R., Prusiner, S.B., (1985) Cell, 41, p. 221

Forloni, G., Angeretti, N., Chiesa, R., Monzani, E., Salmona, M., Bugiani, O., Tagliavini, F., (1993) Nature, 362, p. 543

Tagliavini, F., Prelli, F., Varga, L., Giaccone, G., Sarma, R., Gorevic, P., Ghetti, B., Frangione, B., (1993) Proc. Natl. Acad. Sci. USA, 90, p. 9678

Brown, D.R., Schmidt, B., Kretzschmar, H.A., (1996) Nature, 380, p. 345

Jobling, M.F., Stewart, L.R., White, A.R., McLean, C., Friedhuber, A., Maher, F., Beyereuther, K., Cappai, R., (1999) J. Neurochem., 73, p. 1557

Selvaggini, C., De Gioia, L., Cantù, L., Ghibaudi, E., Diomede, L., Passerini, F., Forloni, G., Salmona, M., (1993) Biochem. Biophys. Res. Commun., 194, p. 1380

Forloni, G., Del Bo, R., Angeretti, N., Chiesa, R., Smiroldo, S., Doni, R., Ghibaudi, E., Tagliavini, F., (1994) Eur. J. Neurosci., 6, p. 1415

Jobling, M.F., Huang, X., Stewart, L.R., Benham, K.J., Curtain, C., Volitakis, I., Perugini, M., Cappai, R., (2001) Biochemistry, 40, p. 8073

Rymer, D.L., Good, T.A., (2000) J. Neurochem., 75, p. 2536

Grasso, D., Milardi, D., La Rosa, C., Rizzarelli, E., (2001) New J. Chem., 25, p. 1543

Brown, D.R., (2001) Brain Res. Bulletin, 55, p. 165

Kayed, R., Head, E., Thompson, J.L., McIntire, T.M., Milton, S.C., Cotman, C.W., Glabe, C.G., (2003) Science, 300, p. 486

Kourie, J.I., Farrelly, P.V., Henry, C.L., (2001) J. Neurochem. Res., 66, p. 214

Gajdusek, D. C., Gibbs, C. J., Alpers, M., (1966) Nature, 209, p. 79

Prusiner, S. B., (1998) Proc. Natl. Acad. Sci. USA, 95, p. 13363

Bolton, D. C., McKinley, M. P., Prusiner, S. B., (1982) Science, 218, p. 1309

McKinley, M. P., Bolton, D. C., Prusiner, S. B., (1983) Cell, 35, p. 57

De Armond, S. J., McKinley, M. P., Barry, R. A., Braunfeld, M. B., McColloch, J. R., Prusiner, S. B., (1985) Cell, 41, p. 221

Brown, D. R., Schmidt, B., Kretzschmar, H. A., (1996) Nature, 380, p. 345

Jobling, M. F., Stewart, L. R., White, A. R., McLean, C., Friedhuber, A., Maher, F., Beyereuther, K., Cappai, R., (1999) J. Neurochem., 73, p. 1557

Jobling, M. F., Huang, X., Stewart, L. R., Benham, K. J., Curtain, C., Volitakis, I., Perugini, M., Cappai, R., (2001) Biochemistry, 40, p. 8073

Rymer, D. L., Good, T. A., (2000) J. Neurochem., 75, p. 2536

Brown, D. R., (2001) Brain Res. Bulletin, 55, p. 165

Kourie, J. I., Farrelly, P. V., Henry, C. L., (2001) J. Neurochem. Res., 66, p. 214



Differential scanning calorimetric (DSC) experiments have shown that the ability of PrP106-126 to perturb 1,3-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) model membranes is differently affected by Cu(++) and Zn(++) ions.
Nessun risultato.

Ricerca avanzata▼
Contiene: [X]      Estesa     Autori: [X]  Tipo di lavoro: [X]   Data iniziale: Data finale: [X]      Sede: Affiliazione IBB     
    
[Pulisci modulo]
Vai a fine pagina   Versione per copia e incolla facile   Esporta tutto in BibTeX   Esporta tutto in EndNote


Oliveri V, Lanza V, Milardi D, Viale M, Maric I, Sgarlata C, Vecchio G
* Amino- and chloro-8-hydroxyquinolines and their copper complexes as proteasome inhibitors and antiproliferative agents (56 visite)
METALLOMICS (ISSN: 1756-5901), 2017 Oct 18; 9(10): 1439-1446.
Impact Factor: 4.069
Dettagli    Esporta in BibTeX    Esporta in EndNote

Dell'Acqua S, Bacchella C, Monzani E, Nicolis S, Di Natale G, Rizzarelli E, Casella L
* Prion Peptides Are Extremely Sensitive to Copper Induced Oxidative Stress (99 visite)
INORG CHEM (ISSN: 0020-1669), 2017 Sep 18; 56(18): 11317-11325.
Impact Factor: 4.7
Dettagli    Esporta in BibTeX    Esporta in EndNote

Magrì A, Tabbì G, Breglia R, De Gioia L, Fantucci P, Bruschi M, Bonomo RP, La Mendola D
* Copper ion interaction with the RNase catalytic site fragment of the angiogenin protein: an experimental and theoretical investigation (69 visite) (PDF 79 visite)
DALTON T (ISSN: 1477-9226), 2017 Jul 04; 46(26): 8524-8538.
Impact Factor: 4.099
Dettagli    Esporta in BibTeX    Esporta in EndNote

Barresi V, Spampinato G, Musso N, Trovato Salinaro A, Rizzarelli E, Condorelli DF
* ATOX1 gene silencing increases susceptibility to anticancer therapy based on copper ionophores or chelating drugs (440 visite)
J INORG BIOCHEM (ISSN: 0162-0134), 2016; 156: 145-152.
Impact Factor: 3.348
Dettagli    Esporta in BibTeX    Esporta in EndNote

Di Natale G, Turi I, Pappalardo G, Sóvágó I, Rizzarelli E
* Cross-Talk Between the Octarepeat Domain and the Fifth Binding Site of Prion Protein Driven by the Interaction of Copper(II) with the N-terminus (113 visite)
CHEM-EUR J (ISSN: 0947-6539), 2015 Mar 2; 21(10): 4071-4084.
Impact Factor: 5.771
Dettagli    Esporta in BibTeX    Esporta in EndNote

Giacomelli C, Trincavelli ML, Satriano C, Hansson O, La Mendola D, Rizzarelli E, Martini C
* Copper (II) ions modulate Angiogenin activity in human endothelial cells (126 visite)
INT J BIOCHEM CELL B (ISSN: 1357-2725), 2015 Mar; 60: 185-196.
Impact Factor: 3.905
Dettagli    Esporta in BibTeX    Esporta in EndNote

Tabbì G, Magrì A, Giuffrida A, Lanza V, Pappalardo  G, Naletova I, Nicoletti VG, Attanasio F, Rizzarelli E
* Semax, an ACTH4-10 peptide analog with high affinity for copper(II) ion and protective ability against metal induced cell toxicity (165 visite)
J INORG BIOCHEM (ISSN: 0162-0134), 2015 Jan; 142: 39-46.
Impact Factor: 3.205
Dettagli    Esporta in BibTeX    Esporta in EndNote

Benetti F, Biarnés X, Attanasio F, Giachin G, Rizzarelli E, Legname G
* Structural determinants in prion protein folding and stability (145 visite)
J MOL BIOL (ISSN: 0022-2836), 2014 Nov 11; 426(22): 3796-3810.
Impact Factor: 4.333
Dettagli    Esporta in BibTeX    Esporta in EndNote

Sinopoli A, Magri A, Milardi D, Pappalardo M, Pucci P, Flagiello A, Titman JJ, Nicoletti VG, Caruso G, Pappalardo G, GrassoG
* The role of copper(II) in the aggregation of human amylin (190 visite)
METALLOMICS (ISSN: 1756-5901), 2014 Oct; 6(10): 1841-1852.
Impact Factor: 3.585
Dettagli    Esporta in BibTeX    Esporta in EndNote

La Mendola D, Rizzarelli E
* Evolutionary implications of metal binding features in different species' prion protein: an inorganic point of view (132 visite)
Biomolecules (ISSN: 2218-273x), 2014 May 23; 4(2): 546-565.
Impact Factor: 2.095
Dettagli    Esporta in BibTeX    Esporta in EndNote

Bellia F, GrassoG
* The role of copper(II) and zinc(II) in the degradation of human and murine IAPP by insulin-degrading enzyme (134 visite)
J MASS SPECTROM (ISSN: 1076-5174), 2014; 49(4): 274-279.
Impact Factor: 2.379
Dettagli    Esporta in BibTeX    Esporta in EndNote

Montefusco S, Esposito R, D'Andrea L, Monti MC, Dunne C, Dolan B, Tosco A, Marzullo L, Clyne M
* Copper promotes TFF1-mediated Helicobacter pylori colonization (121 visite)
Plosone (ISSN: 1932-6203, 1932-6203electronic), 2013 Nov 13; 8(11): e79455-e79455.
Impact Factor: 3.534
Dettagli    Esporta in BibTeX    Esporta in EndNote

De Simonea A, Stanzione F, Marasco D, Vitagliano L, Esposito L
* The Intrinsic Stability Of The Human Prion Beta-Sheet Region Investigated By Molecular Dynamics (174 visite)
Journal Of Biomolecular Structure & Dynamics, 2013 May 1; 31(5): 441-452.
Impact Factor: 2.983
Dettagli    Esporta in BibTeX    Esporta in EndNote

Grasso G, Salomone F, Tundo GR, Pappalardo G, Ciaccio C, Spoto G, Pietropaolo A, Coletta M, Rizzarelli E
* Metal ions affect insulin-degrading enzyme activity (110 visite)
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2012 Dec; 117: 351-358.
Impact Factor: 3.197
Dettagli    Esporta in BibTeX    Esporta in EndNote

Roviello GN, Roviello G, Musumeci D, Bucci EM, Pedone C
* Dakin-West reaction on 1-thyminyl acetic acid for the synthesis of 1, 3-bis(1-thyminyl)-2-propanone, a heteroaromatic compound with nucleopeptide-binding properties (125 visite)
Amino Acids (ISSN: 1438-2199, 0939-4451, 1438-2199electronic), 2012 Oct; 43(4): 1615-1623.
Impact Factor: 3.914
Dettagli    Esporta in BibTeX    Esporta in EndNote

Jószai V, Turi I, Kállay C, Pappalardo G, Di Natale G, Rizzarelli E, Sóvágó I
* Mixed metal copper(II)-nickel(II) and copper(II)-zinc(II) complexes of multihistidine peptide fragments of human prion protein (155 visite)
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2012 Jul; 112: 17-24.
Impact Factor: 3.197
Dettagli    Esporta in BibTeX    Esporta in EndNote

Travaglia A, Pietropaolo A, La Mendola D, Nicoletti VG, Rizzarelli E
* The inorganic perspectives of neurotrophins and Alzheimer's disease (189 visite)
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2012 Jun; 111: 130-137.
Impact Factor: 3.197
Dettagli    Esporta in BibTeX    Esporta in EndNote

Galdiero S, Russo L, Falanga A, Cantisani M, Vitiello M, Fattorusso R, Malgieri G, Galdiero M, Isernia C
* Structure and Orientation of the gH625-644 Membrane Interacting Region of Herpes Simplex Virus Type 1 in a Membrane Mimetic System (97 visite)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2012 Apr 10; 51(14): 3121-3128.
Impact Factor: 3.377
Dettagli    Esporta in BibTeX    Esporta in EndNote

Kállay C, Dávid A, Timári S, Nagy EM, Sanna D, Garribba E, Micera G, De Bona P, Pappalardo G, Rizzarelli E, Sóvágó I
* Copper(II) complexes of rat amylin fragments (139 visite)
Dalton Trans (ISSN: 1477-9234, 1477-9226, 1477-9234electronic), 2011 Oct 14; 40(38): 9711-9721.
Impact Factor: 3.838
Dettagli    Esporta in BibTeX    Esporta in EndNote

Benetti F, Biarnes X, Attanasio F, Rizzarelli E, Laio A, Legname G
* Description and Characterization of a Highly Stable Enthalpic Intermediate State in Mouse Prion Protein Folding (84 visite)
Prion (ISSN: 1933-6896), 2011 Apr; 5: N/D-N/D.
Impact Factor: 2.85
Dettagli    Esporta in BibTeX    Esporta in EndNote

Kállay C, Turi I, Timári S, Nagy Z, Sanna D, Pappalardo G, De Bona P, Rizzarelli E, Sóvágó I
* The effect of point mutations on copper(II) complexes with peptide fragments encompassing the 106-114 region of human prion protein (150 visite)
Monatshefte Fur Chemie (ISSN: 0026-9247), 2011 Apr; 142(4): 411-419.
Impact Factor: 1.532
Dettagli    Esporta in BibTeX    Esporta in EndNote

Vagliasindi LI, Arena G, Bonomo RP, Pappalardo G, Tabbì G
* Copper complex species within a fragment of the N-terminal repeat region in opossum PrP protein (127 visite)
Dalton Trans (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2011 Mar 21; 40(11): 2441-2450.
Impact Factor: 3.838
Dettagli    Esporta in BibTeX    Esporta in EndNote

La Mendola D, Magrì A, Vagliasindi LI, Hansson Ö, Bonomo RP, Rizzarelli E
* Copper(II) complex formation with a linear peptide encompassing the putative cell binding site of angiogenin (111 visite)
Dalton Trans (ISSN: 1477-9234, 1477-9226, 1477-9234electronic), 2010 Nov 28; 39(44): 10678-10684.
Impact Factor: 3.647
Dettagli    Esporta in BibTeX    Esporta in EndNote

Di Natale G, Pappalardo G, Milardi D, Sciacca MF, Attanasio F, La Mendola D, Rizzarelli E
* Membrane interactions and conformational preferences of human and avian prion N-terminal tandem repeats: The role of copper(II) ions, pH, and membrane mimicking environments (156 visite)
J Phys Chem B (ISSN: 1520-6106, 1520-5207, 1520-5207electronic), 2010 Nov 4; 114(43): 13830-13838.
Impact Factor: 3.603
Dettagli    Esporta in BibTeX    Esporta in EndNote

Józsa E, Osz K, Kállay C, de Bona P, Damante CA, Pappalardo G, Rizzarelli E, Sóvágó I
* Nickel(ii) and mixed metal complexes of amyloid-β N-terminus (148 visite)
Dalton Trans (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2010 Sep 14; 39(30): 7046-7053.
Impact Factor: 3.647
Dettagli    Esporta in BibTeX    Esporta in EndNote

Turi I, Kállay C, Szikszai D, Pappalardo G, Di Natale G, De Bona P, Rizzarelli E, Sóvágó I
* Nickel(II) complexes of the multihistidine peptide fragments of human prion protein (119 visite)
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2010 Sep; 104(8): 885-891.
Impact Factor: 3.317
Dettagli    Esporta in BibTeX    Esporta in EndNote

Benetti F, Pastorino L, Attanasio F, Rizzarelli E, Legname G
* Insights into Prion Protein Stability (109 visite)
Prion (ISSN: 1933-6896), 2010 Jul; 4(3): N/D-N/D.
Impact Factor: 2.468
Dettagli    Esporta in BibTeX    Esporta in EndNote

La Mendola D, Magrì A, Campagna T, Campitiello MA, Raiola L, Isernia C, Hansson O, Bonomo RP, Rizzarelli E
* A doppel alpha-helix peptide fragment mimics the copper(II) interactions with the whole protein (392 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2010 Jun 1; 16(21): 6212-6223.
Impact Factor: 5.476
Dettagli    Esporta in BibTeX    Esporta in EndNote

Di Natale G, Pappalardo G, Milardi D, Sciacca MFM, Attanasio F, La Mendola D, Rizzarelli E
* Different Interactions Of Human And Avian Prion Proteins N-Terminal Tandem Repeat Peptides And Their Copper (ii) Complexes With Model Membranes (128 visite)
Journal Of Chemical Physics, 2010; 114: 13830-13838.
Impact Factor: 2.028
Dettagli    Esporta in BibTeX    Esporta in EndNote

Jozsa E, Hosz K, Kallay C, De Bona P, Damante CA, Pappalardo G, Rizzarelli E, Sovago I
* Nickel (ii) And Mixed Metal Complexes Of Amyloid-B N-Terminus. Results Of Potentiometric And Spectroscopic Studies On The Binary Nickel (ii) And Mixed Metal Nickel (ii)-Copper (ii) And Nickel (ii)-Copper (ii)-Zinc (ii) Complexes Of Peptide Fragments (174 visite)
Dalton Trans (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2010; 39(30): 7046-7053.
Impact Factor: 3.647
Dettagli    Esporta in BibTeX    Esporta in EndNote

Palladino P, Ronga L, Benedetti E, Rossi F, Ragone R
* Peptide Fragment Approach to Prion Misfolding: The Alpha-2 Domain (127 visite)
Int J Pept Res Ther (ISSN: 1573-3149, 0929-5666), 2009 Sep; 15(3): 165-176.
Impact Factor: 0.869
Dettagli    Esporta in BibTeX    Esporta in EndNote

Pietropaolo A, Muccioli L, Zannoni C, Rizzarelli E
* Conformational preferences of the full chicken prion protein in solution and its differences with respect to mammals (110 visite)
Chemphyschem (ISSN: 1439-7641, 1439-4235, 1439-7641electronic), 2009 Jul 13; 10(9-10): 1500-1510.
Impact Factor: 3.453
Dettagli    Esporta in BibTeX    Esporta in EndNote

La Mendola D, Pietropaolo A, Pappalardo G, Zannoni C, Rizzarelli E
* Prion Proteins Leading to Neurodegeneration (vol 5, pg 579, 2008) (93 visite)
Current Alzheimer Research (ISSN: 1567-2050), 2009 Jun; 6(3): N/D-N/D.
Impact Factor: 4.971
Dettagli    Esporta in BibTeX    Esporta in EndNote

Di Natale G, Osz K, Nagy Z, Sanna D, Micera G, Pappalardo G, Sovago I, Rizzarelli E
* The Interaction Of Copper (ii) With The Prion Peptide Fragment Huprp (76-114) Encompassing Four Histidyl Residues Within And Outside The Octarepeat Domain (114 visite)
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 2009 May 4; 48(9): 4239-4250.
Impact Factor: 4.657
Dettagli    Esporta in BibTeX    Esporta in EndNote

La Mendola D, Magrì A, Hansson O, Bonomo RP, Rizzarelli E
* Copper(II) complexes with peptide fragments encompassing the sequence 122-130 of human doppel protein (106 visite)
Journal Of Inorganic Biochemistry, 2009 May; 103(5): 758-765.
Impact Factor: 3.444
Dettagli    Esporta in BibTeX    Esporta in EndNote

Bonomo RP, Di Natale G, Rizzarelli E, Tabbì G, Vagliasindi LI
* Copper(II) complexes of prion protein PEG11-tetraoctarepeat fragment: spectroscopic and voltammetric studies (94 visite)
Dalton Trans (ISSN: 1477-9226, 1477-7922, 1477-9234), 2009 Apr 14; (14): 2637-2646.
Impact Factor: 2.908
Dettagli    Esporta in BibTeX    Esporta in EndNote

Ronga L, Palladino P, Ragone R, Benedetti E, Rossi F
* A thermodynamic approach to the conformational preferences of the 180-195 segment derived from the human prion protein α2-helix (100 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009; 15(1): 30-35.
Impact Factor: 1.807
Dettagli    Esporta in BibTeX    Esporta in EndNote

La Mendola D, Pietropaolo A, Pappalardo G, Zannoni C, Rizzarelli E
* Prion proteins leading to neurodegeneration (140 visite)
Current Alzheimer Research (ISSN: 1567-2050), 2008 Dec; 5(6): 579-590.
Impact Factor: 4.132
Dettagli    Esporta in BibTeX    Esporta in EndNote

Bonomo RP, Pappalardo G, Rizzarelli E, Tabbì G, Vagliasindi LI
* Studies of nitric oxide interaction with mono- and dinuclear copper(II) complexes of prion protein bis-octarepeat fragments (140 visite)
Dalton Trans (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2008 Sep 7; (29): 3805-3816.
Impact Factor: 3.58
Dettagli    Esporta in BibTeX    Esporta in EndNote

Pappalardo M, Sciacca MFM, Milardi D, Grasso DM, La Rosa C
* Thermodynamics Of Azurin Folding: The Role Of The Copper Ion (102 visite)
Journal Of Thermal Analysis And Calorimetry (ISSN: 1388-6150), 2008 Sep; 93(2): 575-581.
Impact Factor: 1.63
Dettagli    Esporta in BibTeX    Esporta in EndNote

Pietropaolo A, Muccioli L, Zannoni C, La Mendola D, Maccarrone G, Pappalardo G, Rizzarelli E
* Unveiling the role of histidine and tyrosine residues on the conformation of the avian prion hexarepeat domain (105 visite)
J Phys Chem B (ISSN: 1520-6106, 1520-5207, 1520-5207electronic), 2008 Apr 24; 112(16): 5182-5188.
Impact Factor: 4.189
Dettagli    Esporta in BibTeX    Esporta in EndNote

De Simone A, Pedone C, Vitagliano L
* Structure, dynamics, and stability of assemblies of the human prion fragment SNQNNF (160 visite)
Biochem Biophys Res Commun (ISSN: 1090-2104, 0006-291x, 1090-2104electronic), 2008 Feb 15; 366(3): 800-806.
Impact Factor: 2.648
Dettagli    Esporta in BibTeX    Esporta in EndNote

Bellia F, Amorini AM, La Mendola D, Vecchio G, Tavazzi B, Giardina B, Di Pietro V, Lazzarino G, Rizzarelli E
* New glycosidic derivatives of histidine-containing dipeptides with antioxidant properties and resistant to carnosinase activity (130 visite)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 1768-3254electronic), 2008 Feb; 43(2): 373-380.
Impact Factor: 2.882
Dettagli    Esporta in BibTeX    Esporta in EndNote

Ronga L, Palladino P, Saviano G, Tancredi T, Benedetti E, Ragone R, Rossi F
* Structural characterization of a neurotoxic threonine-rich peptide corresponding to the human prion protein α2-helical 180-195 segment and comparison with full-length α2-helix-derived peptides (140 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2008; 14(10): 1096-1102.
Impact Factor: 1.654
Dettagli    Esporta in BibTeX    Esporta in EndNote

Bonomo RP, Pappalardo G, Rizzarelli E, Santoro AM, Tabbì G, Vagliasindi LI
* Nitrogen oxide interaction with copper complexes formed by small peptides belonging to the prion protein octa-repeat region (145 visite)
Dalton Trans (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2007 Apr 14; (14): 1400-1408.
Impact Factor: 3.212
Dettagli    Esporta in BibTeX    Esporta in EndNote

Ronga L, Langella E, Palladino P, Marasco D, Tizzano B, Saviano M, Pedone C, Improta R, Ruvo M
* Does Tetracycline Bind Helix 2 Of Prion? An Integrated Spectroscopical And Computational Study Of The Interaction Between The Antibiotic And Alpha Helix 2 Human Prion Protein Fragments (150 visite)
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2007 Feb 15; 66(3): 707-715.
Impact Factor: 3.354
Dettagli    Esporta in BibTeX    Esporta in EndNote

Ronga L, Palladino P, Costantini S, Facchiano A, Ruvo M, Benedetti E, Ragone R, Rossi F
* Conformational diseases and structure-toxicity relationships: Lessons from prion-derived peptides (144 visite)
Curr Protein Pept Sci (ISSN: 1389-2037), 2007 Feb; 8(1): 83-90.
Impact Factor: 3.259
Dettagli    Esporta in BibTeX    Esporta in EndNote

Rao M, Russo F, Granata V, Berisio R, Zagari A, Gianfreda L
* Fate of prions in soil: Interaction of a recombinant ovine prion protein with synthetic humic-like mineral complexes (100 visite)
Soil Biol Biochem (ISSN: 0038-0717), 2007 Feb; 39(2): 493-504.
Impact Factor: 2.58
Dettagli    Esporta in BibTeX    Esporta in EndNote

Osz K, Nagy Z, Pappalardo G, Di Natale G, Sanna D, Micera G, Rizzarelli E, Sóvágó I
* Copper(II) interaction with prion peptide fragments encompassing histidine residues within and outside the octarepeat domain: speciation, stability constants and binding details (136 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2007; 13(25): 7129-7143.
Impact Factor: 5.33
Dettagli    Esporta in BibTeX    Esporta in EndNote

Pappalardo M, Milardi D, Grasso D, La Rosa C
* Steered molecular dynamics studies reveal different unfolding pathways of prions from mammalian and non-mammalian species (130 visite)
New J Chem (ISSN: 1144-0546), 2007; 31(6): 901-905.
Impact Factor: 2.651
Dettagli    Esporta in BibTeX    Esporta in EndNote

Ronga L, Palladino P, Tizzano B, Marasco D, Benedetti E, Ragone R, Rossi F
* Effect of salts on the structural behavior of hPrP α2-helix-derived analogues: The counterion perspective (130 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2006 Dec; 12(12): 790-795.
Impact Factor: 1.801
Dettagli    Esporta in BibTeX    Esporta in EndNote

Esposito L, Pedone C, Vitagliano L
* Molecular dynamics analyses of cross-beta-spine steric zipper models: beta-sheet twisting and aggregation (182 visite)
Proc Natl Acad Sci U S A (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2006 Sep 1; 103(31): 11533-11538.
Impact Factor: 9.643
Dettagli    Esporta in BibTeX    Esporta in EndNote

Ronga L, Tizzano B, Palladino P, Ragone R, Urso E, Maffia M, Ruvo M, Benedetti E, Rossi F
* The prion protein: structural features and related toxic peptides (131 visite)
Chem Biol Drug Des Chemical Biology And Drug Design (ISSN: 1747-0277, 1747-0285), 2006 Sep; 68(3): 139-147.
Impact Factor: 2.507
Dettagli    Esporta in BibTeX    Esporta in EndNote

Joszal V, Nagy Z, Osz K, Sanna D, Di Natale G, La Mendola D, Pappalardo G, Rizzarelli E, Sovago I
* Transition metal complexes of terminally protected peptides containing histidyl residues (155 visite)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2006 Sep; 100(8): 1399-1409.
Impact Factor: 2.654
Dettagli    Esporta in BibTeX    Esporta in EndNote

Langella E, Improta R, Crescenzi O, Barone V
* Assessing the acid-base and conformational properties of histidine residues in human prion protein (125-228) by means of pKα calculations and molecular dynamics simulations (180 visite)
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2006 Jul 1; 64(1): 167-177.
Impact Factor: 3.73
Dettagli    Esporta in BibTeX    Esporta in EndNote

Granata V, Palladino P, Tizzano B, Negro A, Berisio R, Zagari A
* The effect of the osmolyte trimethylamine N-oxide on the stability of the prion protein at low pH (82 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2006 Jun 15; 82(3): 234-240.
Impact Factor: 2.48
Dettagli    Esporta in BibTeX    Esporta in EndNote

Barone V, De Rienzo F, Langella E, Menziani MC, Rega N, Sola M
* A computational protocol to probe the role of solvation effects on the reduction potential of azurin mutants (84 visite)
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2006 Jan 1; 62(1): 262-269.
Impact Factor: 3.73
Dettagli    Esporta in BibTeX    Esporta in EndNote

Palladino P, Ronga L, Tizzano B, Rossi F, Ragone R, Tancredi T, Saviano G, Facchiano A, Costantini S, Ruvo M, Benedetti E
* Prion protein misfolding: Conformational stability of the alpha 2-helix (87 visite)
Understanding Biology Using Peptides, 2006; N/D: N/D-N/D.
Impact Factor: 2.614
Dettagli    Esporta in BibTeX    Esporta in EndNote

Grasso D, Grasso G, Guantieri V, Impellizzeri G, La Rosa C, Milardi D, Micera G, Osz K, Pappalardo G, Rizzarelli E, Sanna D, Sovago I
* Environmental effects on a prion's helix II domain: copper(II) and membrane interactions with PrP180-193 and its analogues (103 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2005 Dec 23; 12(2): 537-547.
Impact Factor: 4.907
Dettagli    Esporta in BibTeX    Esporta in EndNote

La Mendola D, Bonomo RP, Impellizzeri G, Maccarrone G, Pappalardo G, Pietropaolo A, Rizzarelli E, Zito V
* Copper(II) complexes with chicken prion repeats: Influence of proline and tyrosine residues on the coordination features (110 visite)
J Biol Inorg Chem (ISSN: 0949-8257, 1432-1327electronic, 0949-8257print), 2005 Sep; 10(5): 463-475.
Impact Factor: 3.224
Dettagli    Esporta in BibTeX    Esporta in EndNote

Tizzano B, Palladino P, De Capua A, Marasco D, Rossi F, Benedetti E, Pedone C, Ragone R, Ruvo M
* The Human Prion Protein Alpha2 Helix: A Thermodynamic Study Of Its Conformational Preferences (112 visite)
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2005 Apr 1; 59(1): 72-79.
Impact Factor: 4.684
Dettagli    Esporta in BibTeX    Esporta in EndNote

Di Natale G, Impellizzeri G, Pappalardo G
* Conformational properties of peptide fragments homologous to the 106-114 and 106-126 residues of the human prion protein: a CD and NMR spectroscopic study (123 visite)
Org Biomol Chem (ISSN: 1477-0520, 1477-0539, 1477-0539electronic), 2005 Feb 7; 3(3): 490-497.
Impact Factor: 2.547
Dettagli    Esporta in BibTeX    Esporta in EndNote

Bonomo RP, Cucinotta V, Giuffrida A, Impellizzeri G, Magrì A, Pappalardo G, Rizzarelli E, Santoro AM, Tabbì G, Vagliasindi LI
* A re-investigation of copper coordination in the octa-repeats region of the prion protein (120 visite)
Dalton Trans (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2005 Jan 7; (1): 150-158.
Impact Factor: 3.003
Dettagli    Esporta in BibTeX    Esporta in EndNote

Langella E, Improta R, Barone V
* Checking the pH-induced conformational transition of prion protein by molecular dynamics simulations: Effect of protonation of histidine residues (145 visite)
Biophysical Journal (ISSN: 0006-3495, 1542-0086), 2004 Dec; 87(6): 3623-3632.
Impact Factor: 4.585
Dettagli    Esporta in BibTeX    Esporta in EndNote

Pappalardo M, Milardi D, La Rosa C, Zannoni C, Rizzarelli E, Grasso D
* A molecular dynamics study on the conformational stability of PrP 180-193 helix II prion fragment (129 visite)
Chemical Physics Letters (ISSN: 0009-2614), 2004 Jun 1; 390(4-6): 511-516.
Impact Factor: 2.438
Dettagli    Esporta in BibTeX    Esporta in EndNote

Galdiero S, Gouaux E
* High Resolution Crystallographic Studies Of Alpha-Hemolysin-Phospholipid Complexes Define Heptamer-Lipid Head Group Interactions: Implication For Understanding Protein-Lipid Interactions (108 visite)
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic), 2004 Jun; 13(6): 1503-1511.
Impact Factor: 4.116
Dettagli    Esporta in BibTeX    Esporta in EndNote

Mineo P, Vitalini D, La Mendola D, Rizzarelli E, Scamporrino E, Vecchio G
* Coordination Features Of Difunctionalized Beta-Cyclodextrins With Carnosine: Esi-Ms And Spectroscopic Investigations On 6a, 6d-Di-(beta-Alanyl-L-Histidine)-6a, 6d-Dideoxy-Beta-Cyclodextrin And 6a, 6c-Di-(beta-Alanyl-L-Histidine)-6a, 6c-Dideoxy-Beta-Cyclodextrin And Their Copper (ii) Complexes (135 visite)
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2004 Feb; 98(2): 254-265.
Impact Factor: 2.225
Dettagli    Esporta in BibTeX    Esporta in EndNote

Brown DR, Guantieri V, Grasso G, Impellizzeri G, Pappalardo G, Rizzarelli E
* Copper(II) complexes of peptide fragments of the prion protein. Conformation changes induced by copper(II) and the binding motif in C-terminal protein region (134 visite)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2004 Jan; 98(1): 133-143.
Impact Factor: 2.225
Dettagli    Esporta in BibTeX    Esporta in EndNote

Barone V, Improta R, Rega N
* Computation of protein pK's values by an integrated density functional theory/Polarizable Continuum Model approach (105 visite)
Theor Chem Acc (ISSN: 1432-881x), 2004; 111(2-6): 237-245.
Impact Factor: 2.209
Dettagli    Esporta in BibTeX    Esporta in EndNote

Tizzano B, Marasco D, Benedetti E, De Capua A, Palladino P, Pedone C, Perretta G, Rossi F, Ragone R, Ruvo M
* Conformational conversion of prion proteins: Role synthetic PRP 173-195 fibrillogenic peptide (115 visite)
Peptide Revolution, 2004; N/D: N/D-N/D.
Impact Factor: 4.659
Dettagli    Esporta in BibTeX    Esporta in EndNote

Pappalardo G, Impellizzeri G, Campagna T
* Copper(II) binding of prion protein's octarepeat model peptides (159 visite)
Inorg Chim Acta (ISSN: 0020-1693), 2004; 357(1): 185-194.
Impact Factor: 1.554
Dettagli    Esporta in BibTeX    Esporta in EndNote

De Luca S, Ragone R, Bracco C, Digilio G, Aloj L, Tesauro D, Saviano M, Pedone C, Morelli G
* A cyclic CCK8 analogue selective for the cholecystokinin type A receptor: design, synthesis, NMR structure and binding measurements (129 visite)
Chembiochem (ISSN: 1439-7633, 1439-4227, 1439-7633electronic), 2003 Nov 7; 4(11): 1176-1187.
Impact Factor: 3.992
Dettagli    Esporta in BibTeX    Esporta in EndNote

La Mendola D, Bonomo R, Maccarrone G, Pappalardo G, Rizzarelli E
* A thermodynamic and spectroscopic study on the copper(II) complexes with hexarepeats fragments of the avian prion protein (133 visite)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2003 Jul 15; 96(1): N/D-N/D.
Impact Factor: 2.343
Dettagli    Esporta in BibTeX    Esporta in EndNote

Milardi D, Grasso DM, Verbeet MP, Canters GW, La Rosa C
* Thermodynamic analysis of the contributions of the copper ion and the disulfide bridge to azurin stability: Synergism among multiple depletions (134 visite)
Arch Biochem Biophys (ISSN: 0003-9861), 2003 Jun 1; 414(1): 121-127.
Impact Factor: 2.338
Dettagli    Esporta in BibTeX    Esporta in EndNote

Bonomo RP, Grasso D, Grasso G, Guantieri V, Impellizzeri G, La Rosa C, Milardi D, Pappalardo G, Tabbì G, Rizzarelli E
* Metal binding to prion protein (123 visite)
Metal-Ligand Interactions - Molecular Nano- Micro- And Macro-Systems In Complex Environments, 2003 Jan 01; 116: 21-39.
Impact Factor: 5.664
Dettagli    Esporta in BibTeX    Esporta in EndNote

Grasso D, Milardi D, Guantieri V, La Rosa C, Rizzarelli E
* Interaction of prion peptide PrP 180-193 with DPPC model membranes: A thermodynamic study (128 visite)
New J Chem (ISSN: 1144-0546), 2003; 27(2): 359-364.
Impact Factor: 2.272
Dettagli    Esporta in BibTeX    Esporta in EndNote

Cucinotta V, Giuffrida A, Grasso G, Maccarrone G, Vecchio G
* Ligand exchange chiral separations by cyclodextrin derivatives in capillary electrophoresis (113 visite)
Analyst (ISSN: 0003-2654), 2003; 128(2): 134-136.
Impact Factor: 2.251
Dettagli    Esporta in BibTeX    Esporta in EndNote

Menziani MC, De Benedetti PG, Langella E, Barone V
* Seeking for binding determinants of the prion protein to human plasminogen (92 visite)
Mol Phys (ISSN: 0026-8976), 2003; 101(17): 2763-2773.
Impact Factor: 1.591
Dettagli    Esporta in BibTeX    Esporta in EndNote

Pappalardo G, Impellizzeri G, Bonomo RP, Campagna T, Grasso G, Saita MG
* Copper(II) and nickel(II) binding modes in a histidine-containing model dodecapeptide (120 visite)
New J Chem (ISSN: 1144-0546), 2002; 26(5): 593-600.
Impact Factor: 2.06
Dettagli    Esporta in BibTeX    Esporta in EndNote

Grasso D, Milardi D, La Rosa C, Rizzarelli E
* DSC study of the interaction of the prion peptide PrP106-126 with artificial membranes (122 visite)
New J Chem (ISSN: 1144-0546), 2001; 25(12): 1543-1548.
Impact Factor: 2.44
Dettagli    Esporta in BibTeX    Esporta in EndNote

Bonomo RP, Imperllizzeri G, Pappalardo G, Rizzarelli E, Tabbì G
Copper(II) binding modes in the prion octapeptide PHGGGWGQ: A spectroscopic and voltammetric study (180 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2000 Nov 17; 6(22): 4195-4202.
Impact Factor: 4.698
Dettagli    Esporta in BibTeX    Esporta in EndNote

Conato C, Contino A, Maccarrone G, Magrì A, Remelli M, Tabbì G
Copper(II) complexes with L-lysine and L-ornithine: Is the side-chain involved in the coordination? A thermodynamic and spectroscopic study (128 visite)
Thermochim Acta (ISSN: 0040-6031), 2000 Nov 13; 362(1-2): 13-23.
Impact Factor: 0.807
Dettagli    Esporta in BibTeX    Esporta in EndNote

Lombardi A, Marasco D, Maglio O, Di Costanzo L, Nasti F, Pavone V
Miniaturized metalloproteins: Application to iron-sulfur proteins (335 visite)
Proc Natl Acad Sci U S A (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2000 Oct 24; 97(22): 11922-11927.
Impact Factor: 10.789
Dettagli    Esporta in BibTeX    Esporta in EndNote

Cucinotta V, Grasso D, Grasso G, Milardi D
Calorimetric evidences for Copper(II)-regulated chiral recognition between decanucleotide 5'd(CTGGATCCAG)2 and Ala-Trp dipeptides (125 visite)
Nucleosides Nucleotides (ISSN: 0732-8311), 1997; 16(10-11): 1847-1854.
Impact Factor: 0.905
Dettagli    Esporta in BibTeX    Esporta in EndNote

Bonomo RP, Marchelli R, Tabbì G
Study of H2O2 interaction with copper(II) complexes with diamino-diamide type ligands, diastereoisomeric dipeptides, and tripeptides (128 visite)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 1995 Nov 15; 60(3): 205-218.
Impact Factor: 1.342
Dettagli    Esporta in BibTeX    Esporta in EndNote

Fattorusso R, Morelli G, Lombardi A, Nastri F,  maglio O, D'Auria G, Pedone C, Pavone V
Design of metal ion binding peptides (159 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1995; 37(6): 401-410.
Impact Factor: 2.425
Dettagli    Esporta in BibTeX    Esporta in EndNote



86 Records (80 escludendo Abstract e Conferenze).
Impact factor totale: 285.441 (265.536 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 301.122 (279.838 escludendo Abstract e Conferenze).







    Esporta in BibTeX    Esporta in EndNote