Clinical impact of correlative [123I]-FP-CIT brain imaging and neurological findings in suspect Parkinson's disease(135 visite) Covelli EM, Brunetti A, Di Lauro A, Sullo P, Mazzarella G, Tedeschi E, Belfiore G
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 2004 Oct; 108(4): 417-425.
Tipo di articolo: Journal Article,
Impact factor: 1.368, Impact factor a 5 anni: 1.47
*** IBB - CNR *** Dipto. di Diagnostica per Immagini, AORN San Sebastiano, Caserta, Italy U.O. di Neurologia, AORN San Sebastiano, Caserta, Italy IBB-CNR, Università Federico II, Napoli, Italy U. O. di Neurologia, AORN San Sebastiano, Caserta, Italy IBB-CNR, Universit Federico II, Napoli, Italy
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Gibb, W. R. G., Less, A. J., The relevance of Lewy Body to the pathogenesis of idiopathic Parkinson's disease (1988) J Neurol Neurosurg Psychiatry, 51, pp. 745-75
Gelb, D. J., Olivier, E., Gilman, S., Diagnostic criteria for Parkinson's disease (1999) Arch Neurol, 56, pp. 33-39
Hughes, A. J., Daniel, S. E., Ben-Shlomo, Y., The accuracy of the clinical diagnosis of parkinsonian syndromes in a specialist movement disorder service (2002) Brain, 125, pp. 861-870
Brooks, D. J., Neuroimaging in movement disorders (1997) Movement Disorders: Neurologic Principles and Practice, pp. 31-48. , Watts RL, Koeller WC (eds). McGraw-Hill, New York
Raiput, A. H., Rozdilsky, B., Rajput, A., Accuracy of clinical diagnosis in parkinsonism. A prospective study (1991) Can J Neurol Sci, 18, pp. 275-278
Bower, J. H., Maraganoe, D. M., McDonnel, S. K., Influence of strict, intermediate, and broad diagnostic criteria on the age- and sex-specific incidence of Parkinson's disease (2000) Mov Disord, 15, pp. 19-25
Gilman, S., Low, P. A., Quinn, N., Consensus statement on the diagnosis of multiple system atrophy (1999) J Neurol Sci, 163, pp. 94-98
Marek, K. L., Seibyl, J. P., Zoghbi, S. S., [123I] beta-CIT SPECT imaging demonstrates bilateral loss of dopamine transporters in hemi-Parkinson's disease (1996) Neurology, 46, pp. 231-237
Benamer, H. T. S., Patterson, J., Grosset, D. G., Accurate differentiation of parkinsonism and essential tremor using visual assessment of [123I] -FP-CIT SPECT imaging: The [123I] -FP-CIT study group (2000) Mov Disord, 15, pp. 503-510
Berendse, H. W., Booij, J., Francot, C. M., Subclinical dopaminergic dysfunction in asymptomatic Parkinson's disease patient's relatives with a decreased sense of smell (2001) Ann Neurol, 50, pp. 34-31
Rubenstain, L. M., Chrischilles, E. A., Voelker, M. D., The impact of Parkinson's disease in Europe: A collaborative study of population-based cohorts (1997) Pharmacoeconomics, 12, pp. 486-498. , Neurologic Diseases in the Elderly Research Group
PURPOSE: Here we report our experience in a general hospital setting using [(123)I]-FP-CIT SPECT to diagnose patients with suspect Parkinson's disease (PD). MATERIALS AND METHODS: Thirty consecutive patients (19M, 11W, mean age: 61+/-13 years) were prospectively studied. Patients underwent MRI (27) at 1.5T or CT (3) when MRI was contraindicated, to rule out focal brain abnormalities. Motor and cognitive function were evaluated by neurologists with UPDRS and Hoehn e Yahr Scale. [(123)I]-FP-CIT striatal uptake, assessed with SPECT, was classified as normal, non-diagnostic, abnormal (unilateral or bilateral). Imaging results (SPECT+MRI) were correlated with the neurological findings. RESULTS: In 5 patients the [(123)I]-FP-CIT brain SPECT was normal, suggesting that their symptoms could be related to a benign disorder such as essential tremor. Two patients had non-diagnostic [(123)I]-FP-CIT brain SPECT, with MRI/CT findings compatible with subcortical cerebrovascular disease. In the remaining 23 patients abnormal striatal [(123)I]-FP-CIT uptake correlated with neurological findings, significantly increasing the probability of Parkinson's disease. In these patients MRI/CT scans were normal, or showed a mild BA, or mild cerebral vascular disease (mild CVD). CONCLUSIONS: Our results suggest that [(123)I]-FP-CIT scan could be used routinely in clinical practice to support the diagnosis of PD and to differentiate between other conditions. Moreover, FP-CIT could significantly impact treatment selection and follow-up of these patients.
Kim YH, Shin SW, Pellicano R, Fagoonee S, Choi IJ, Kim YI, Park B, Choi JM, Kim SG, Choi J, Park JY, Oh S, Yang HJ, Lim JH, Im JP, Kim JS, Jung HC, Ponzetto A, Figura N, Malfertheiner P, Choi IJ, Kook MC, Kim YI, Cho SJ, Lee JY, Kim CG, Park B, Nam BH, Bae SE, Choi KD, Choe J, Kim SO, Na HK, Choi JY, Ahn JY, Jung KW, Lee J, Kim DH, Chang HS, Song HJ, Lee GH, Jung HY, Seta T, Takahashi Y, Noguchi Y, Shikata S, Sakai T, Sakai K, Yamashita Y, Nakayama T, Leja M, Park JY, Murillo R, Liepniece-karele I, Isajevs S, Kikuste I, Rudzite D, Krike P, Parshutin S, Polaka I, Kirsners A, Santare D, Folkmanis V, Daugule I, Plummer M, Herrero R, Tsukamoto T, Nakagawa M, Kiriyama Y, Toyoda T, Cao X, Corral JE, Mera R, Dye CW, Morgan DR, Lee YC, Lin JT, Garcia Martin R, Matia Cubillo A, Lee SH, Park JM, Han YM, Ko WJ, Hahm KB, Leontiadis GI, Ford AC, Ichinose M, Sugano K, Jeong M, Park JM, Han YM, Park KY, Lee DH, Yoo JH, Cho JY, Hahm KB, Bang CS, Baik GH, Shin IS, Kim JB, Suk KT, Yoon JH, Kim YS, Kim DJ * Helicobacter pylori Eradication for Prevention of Metachronous Recurrence after Endoscopic Resection of Early Gastric Cancer(38 visite) N Engl J Med (ISSN: 0028-4793, 0028-4793linking, 1533-4406electronic), 2015 Jun; 30642104201566393291: 749-756. Impact Factor:59.558 DettagliEsporta in BibTeXEsporta in EndNote
Antonini A, Vitale C, Barone P, Cilia R, Righini A, Bonuccelli U, Abbruzzese G, Ramat S, Petrone A, Quatrale R, Marconi R, Ceravolo R, Stefani A, Lopiano L, Zappia M, Capus L, Morgante L, Tamma F, Tinazzi M, Colosimo C, Guerra UP, Valzania F, Fagioli G, Distefano A, Bagnato A, Feggi L, Anna S, Maria Teresa Rosaria De Cr, Nobili F, Mazzuca N, Baldari S, Eleopra R, Bestetti A, Benti R, Varrone A, Volterrani D, Massa R, Stocchi F, Schillaci O, Dore F, Zibetti M, Castellano G, Battista SG, Giorgetti G * The relationship between cerebral vascular disease and parkinsonism: The VADO study(199 visite) Parkinsonism Relat D (ISSN: 1353-8020, 1873-5126, 1873-5126electronic), 2012; 18(6): 775-780. Impact Factor:3.274 DettagliEsporta in BibTeXEsporta in EndNote
353 Records (339 escludendo Abstract e Conferenze). Impact factor totale: 1238.152 (1189.871 escludendo Abstract e Conferenze). Impact factor a 5 anni totale: 1374.241 (1314.227 escludendo Abstract e Conferenze).
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