The effects of ionizing radiations on valyl tRNA synthetase (L-valine tRNA ligase (AMP), E.C.22.214.171.124), purified from rat liver and Morris hepatoma 7777, are reported. The results showed that: the enzymatic activity is strongly inhibited by radiation; the enzymatic inactivation is much more marked in dilute than in concentrated solutions; the inactivation of enzyme is linked to the oxidation of sulfhydryl groups indispensable to the catalytic activity of the enzyme; no substantial difference in relation to inactivation by radiation was observed between rat liver and Morris hepatoma 7777 enzymes.
162 Records (140 escludendo Abstract e Conferenze). Impact factor totale: 522.239 (463.551 escludendo Abstract e Conferenze). Impact factor a 5 anni totale: 625.074 (560.663 escludendo Abstract e Conferenze).