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Cation effect on the electronic excited states of guanine nanostructures studied by time-resolved fluorescence spectroscopy (122 visite)

Hua Y, Changenet-Barret P, Improta R, Vaya I, Gustavsson T, Kotlyar AB, Zikich D, Sket P, Plavec J, Markovitsi D

J Phys Chem C (ISSN: 1932-7447), 2012 Jul 12; 116(27): 14682-14689.

Tipo di articolo: Journal Article,

Impact factor: 4.814

Impact factor a 5 anni: 5.152


Parole chiave: Cation Effects, Charge-Transfer Excited State, Electronic Coupling, Electronic Excited State, Excited State Relaxation, Femtoseconds, Fluorescence Anisotropy Decay, Fluorescence Decays, Franck-Condon, Geometrical Arrangements, In-Line, Inter-Proton Distance, Nmr Measurements, Quadruplexes, Quantum Calculation, Steady-State Emissions, Subnanosecond, Time-Resolved Fluorescence Spectroscopy, Time-Scales, Uv Absorption Spectrum, Charge Transfer, Electric Excitation, Emission Spectroscopy, Excitons, Metal Ions, Nanostructures, Positive Ions,

Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84863847007&partnerID=40&md5=c83b71fe52ea711e464d2f1d3d9cb01f

The effect of metal ions on the excited states of guanine nanostructures, short d(TG4T) 4 quadruplexes and long G4-wires, are studied by fluorescence spectroscopy. The steady-state emission spectra show that both systems exhibit a strong cation effect. Fluorescence decays and fluorescence anisotropy decays, recorded from the femtosecond to the nanosecond time-scale, reveal the following picture. In the presence of K +, emission arises mainly from delocalized ππ* states (excitons), whose decay spans several decades of times. In contrast, the fluorescence in the presence of Na + is dominated by emission from charge transfer excited states decaying essentially on the subnanosecond time-scale. Such a difference is not due to the initially populated (Franck-Condon) states. The interproton distances derived from two-dimensional NMR measurements on the ground state of d(TG4T) 4 show that the geometrical arrangement of guanines, governing the electronic coupling, is the same for both cations, in line with the UV absorption spectra. The observed cation effect is correlated with the excited state relaxation: the increased mobility of Na + ions within the quadruplex favors trapping of ππ* excitons by charge transfer excited states, whereas such a process is hindered for the larger K + ions. This is rationalized by quantum calculations on two stacked guanine tetrads. © 2012 American Chemical Society.
*** IBB - CNR ***

CNRS, IRAMIS, Laboratoire Francis Perrin, 91191 Gif-sur-Yvette, France

Istituto Biostrutture e Bioimmagini-CNR, Via Mezzocannone 16, I-80134 Napoli, Italy

Department of Biochemistry, Georges S. Wise Faculty of Life Sciences, Tel Aviv University, Ramat Aviv, 69978, Israel

Slovenian NMR Center, National Institute of Chemistry, Hajdrihova 19, SI-1001 Ljubljana, Slovenia
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Mergny, J. L., De Cian, A., Ghelab, A., Sacca, B., Lacroix, L., (2005) Nucleic Acids Res., 33, pp. 81-94

Xu, Q. W., Deng, H., Braunlin, W. H., (1993) Biochemistry, 32, pp. 13130-13137

Hud, N. V., Smith, F. W., Anet, F. A. L., Feigon, J., (1996) Biochemistry, 35, pp. 15383-15390

Miannay, F. A., Gustavsson, T., Banyasz, A., Markovitsi, D., (2010) J. Phys. Chem. A, 114, pp. 3256-3263

Albrecht, A. C., (1961) J. Mol. Spectrosc., 6, p. 84

Barnett, R. N., Cleveland, C. L., Joy, A., Landman, U., Schuster, G. B., (2001) Science, 294, pp. 567-571

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Contiene: [X]      Estesa         Autori: [X]      Tipo di lavoro: [X]
Data iniziale: Data finale: [X]      Sede: Affiliazione IBB     
    
[Pulisci modulo]
Banyasz A, Gustavsson T, Onidas D, Changenet-Barret P, Markovitsi D, Improta R
* Multi-pathway excited state relaxation of adenine oligomers in aqueous solution: A joint theoretical and experimental study (89 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2013 Mar; 19(11): 3762-3774.
Dettagli    Esporta in BibTeX    Esporta in EndNote

Banyasz A, Douki T, Improta R, Gustavsson T, Onidas D, Vaya I, Perron M, Markovitsi D
* Electronic excited states responsible for dimer formation upon UV absorption directly by thymine strands: Joint experimental and theoretical study (120 visite)
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126), 2012 Sep 12; 134(36): 14834-14845.
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Improta R, Santoro F, Barone V, Lami A
* Vibronic model for the quantum dynamical study of the competition between bright and charge-transfer excited states in single-strand polynucleotides: the adenine dimer case (80 visite)
J Phys Chem A (ISSN: 1089-5639, 1520-5215electronic, 1089-5639linking), 2009 Dec 31; 113(52): 15346-15354.
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3 Records (3 escludendo Abstract e Conferenze).
Impact factor totale: 19.272 (19.272 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 18.825 (18.825 escludendo Abstract e Conferenze).







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