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Cation effect on the electronic excited states of guanine nanostructures studied by time-resolved fluorescence spectroscopy (53 views)

Hua Y, Changenet-Barret P, Improta R, Vaya I, Gustavsson T, Kotlyar AB, Zikich D, Sket P, Plavec J, Markovitsi D

J Phys Chem C (ISSN: 1932-7447), 2012 Jul 12; 116(27): 14682-14689.

Abstract
The effect of metal ions on the excited states of guanine nanostructures, short d(TG4T) 4 quadruplexes and long G4-wires, are studied by fluorescence spectroscopy. The steady-state emission spectra show that both systems exhibit a strong cation effect. Fluorescence decays and fluorescence anisotropy decays, recorded from the femtosecond to the nanosecond time-scale, reveal the following picture. In the presence of K +, emission arises mainly from delocalized ππ* states (excitons), whose decay spans several decades of times. In contrast, the fluorescence in the presence of Na + is dominated by emission from charge transfer excited states decaying essentially on the subnanosecond time-scale. Such a difference is not due to the initially populated (Franck-Condon) states. The interproton distances derived from two-dimensional NMR measurements on the ground state of d(TG4T) 4 show that the geometrical arrangement of guanines, governing the electronic coupling, is the same for both cations, in line with the UV absorption spectra. The observed cation effect is correlated with the excited state relaxation: the increased mobility of Na + ions within the quadruplex favors trapping of ππ* excitons by charge transfer excited states, whereas such a process is hindered for the larger K + ions. This is rationalized by quantum calculations on two stacked guanine tetrads. © 2012 American Chemical Society.

Affiliations ▼
*** IBB - CNR Affiliation

CNRS, IRAMIS, Laboratoire Francis Perrin, 91191 Gif-sur-Yvette, France

Istituto Biostrutture e Bioimmagini-CNR, Via Mezzocannone 16, I-80134 Napoli, Italy

Department of Biochemistry, Georges S. Wise Faculty of Life Sciences, Tel Aviv University, Ramat Aviv, 69978, Israel

Slovenian NMR Center, National Institute of Chemistry, Hajdrihova 19, SI-1001 Ljubljana, Slovenia

Details ▼
Impact factor: 4.814, 5-year impact factor: 5.152

Paper type: Journal Article,

Keywords: Cation Effects, Charge-Transfer Excited State, Electronic Coupling, Electronic Excited State, Excited State Relaxation, Femtoseconds, Fluorescence Anisotropy Decay, Fluorescence Decays, Franck-Condon, Geometrical Arrangements, In-Line, Inter-Proton Distance, Nmr Measurements, Quadruplexes, Quantum Calculation, Steady-State Emissions, Subnanosecond, Time-Resolved Fluorescence Spectroscopy, Time-Scales, Uv Absorption Spectrum, Charge Transfer, Electric Excitation, Emission Spectroscopy, Excitons, Metal Ions, Nanostructures, Positive Ions,

Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84863847007&partnerID=40&md5=c83b71fe52ea711e464d2f1d3d9cb01f

References ▼
De Cian, A., Lacroix, L., Douarre, C., Temime-Smaali, N., Trentesaux, C., Riou, J.F., Mergny, J.L., (2008) Biochimie, 90, pp. 131-15

Davis, J.T., Spada, G.P., (2007) Chem. Soc. Rev., 36, pp. 296-313

Rochette, P.J., Brash, D.E., (2010) PLoS Genet., 6, p. 1000926

Mergny, J.L., Phan, A.T., Lacroix, L., (1998) FEBS Lett., 435, pp. 74-78

Mendez, M.A., Szalai, V.A., (2009) Biopolymers, 91, pp. 841-850

Dao, N.T., Haselsberger, R., Michel-Beyerle, M.E., Phan, A.T., (2011) FEBS Lett., 585, pp. 3969-3977

Markovitsi, D., Gustavsson, T., Sharonov, A., (2004) Photochem. Photobiol., 79, pp. 526-530

Gepshtein, R., Huppert, D., Lubitz, I., Amdursky, N., Kotlyar, A.B., (2008) J. Phys. Chem. C, 112, pp. 12249-12258

Miannay, F.A., Banyasz, A., Gustavsson, T., Markovitsi, D., (2009) J. Phys. Chem. C, 113, pp. 11760-11765

Changenet-Barret, P., Emanuele, E., Gustavsson, T., Improta, R., Kotlyar, A.B., Markovitsi, D., Vaya, I., Zikich, D., (2010) J. Phys. Chem. C, 114, pp. 14339-14346

Schwalb, N.K., Temps, F., (2008) Science, 322, pp. 243-245

Middleton, C.T., De La Harpe, K., Su, C., Law, U.K., Crespo-Hernández, C.E., Kohler, B., (2009) Annu. Rev. Phys. Chem., 60, pp. 217-239

Doorley, G.W., McGovern, D.A., George, M.W., Towrie, M., Parker, A.W., Kelly, J.M., Quinn, S.J., (2009) Angew. Chem., Int. Ed., 48, pp. 123-127

Kwok, W.M., Ma, C.S., Phillips, D.L., (2009) J. Phys. Chem. B, 113, pp. 11527-11534

Fiebig, T., (2009) J. Phys. Chem. B, 113, pp. 9348-9349

Bouvier, B., Gustavsson, T., Markovitsi, D., Millié, P., (2002) Chem. Phys., 275, pp. 75-92

Bittner, E.R., (2006) J. Chem. Phys., 125, pp. 1-12. , 094909

Tonzani, S., Schatz, G.C., (2008) J. Am. Chem. Soc., 130, pp. 7607-7612

Burin, A.L., Dickman, J.A., Uskov, D.B., Hebbard, C.F.F., Schatz, G.C., (2008) J. Chem. Phys., 129, p. 091102

Starikov, E.B., Cuniberti, G., Tanaka, S., (2009) J. Phys. Chem. B, 113, pp. 10428-10435

Lange, A.W., Herbert, J.M., (2009) J. Am. Chem. Soc., 131, pp. 3913-3922

Santoro, F., Barone, V., Improta, R., (2009) J. Am. Chem. Soc., 131, pp. 15232-15245

Improta, R., Barone, V., (2012) Angew. Chem., Int. Ed., pp. 12016-12019

Bouvier, B., Dognon, J.P., Lavery, R., Markovitsi, D., Millié, P., Onidas, D., Zakrzewska, K., (2003) J. Phys. Chem. B, 107, pp. 13512-13522

Sket, P., Plavec, J., (2010) J. Am. Chem. Soc., 132, pp. 12724-12732

Forman, S.L., Fettinger, J.C., Pieraccini, S., Gottareli, G., Davis, J.T., (2000) J. Am. Chem. Soc., 122, pp. 4060-4067

Dumas, A., Luedtke, N.W., (2010) J. Am. Chem. Soc., 132, pp. 18004-18007

Kotlyar, A.B., Borovok, N., Molotsky, T., Cohen, H., Shapir, E., Porath, D., (2005) Adv. Mater., 17, pp. 1901-1905

Shapir, E., Cohen, H., Calzolari, A., Cavazzoni, C., Ryndyk, D.A., Cuniberti, G., Kotlyar, A., Porath, D., (2008) Nat. Mater., 7, pp. 68-74

Mergny, J.L., De Cian, A., Ghelab, A., Sacca, B., Lacroix, L., (2005) Nucleic Acids Res., 33, pp. 81-94

Shapir, E., Sagiv, L., Borovok, N., Molotski, T., Kotlyar, A.B., Porath, D., (2008) J. Phys. Chem. B, 112, pp. 9267-9269

Onidas, D., Markovitsi, D., Marguet, S., Sharonov, A., Gustavsson, T., (2002) J. Phys. Chem. B, 106, pp. 11367-11374

Zhao, Y., Truhlar, D.G., (2008) Acc. Chem. Res., 41, pp. 157-167

Zhao, Y., Schultz, N.E., Truhlar, D.G., (2006) J. Chem. Theory Comput., 2, pp. 364-382

Tomasi, J., Mennucci, B., Cammi, R., (2005) Chem. Rev., 105, pp. 2999-3093

Adamo, C., Barone, V., (1999) J. Chem. Phys., 110, pp. 6158-6170

Ernzerhof, M., Scuseria, G.E., (1999) J. Chem. Phys., 110, pp. 5029-5036

Xu, Q.W., Deng, H., Braunlin, W.H., (1993) Biochemistry, 32, pp. 13130-13137

Hud, N.V., Smith, F.W., Anet, F.A.L., Feigon, J., (1996) Biochemistry, 35, pp. 15383-15390

Zavasnik, J., Podbevsek, P., Plavec, J., (2011) Biochemistry, 50, pp. 4155-4161

Miannay, F.A., Gustavsson, T., Banyasz, A., Markovitsi, D., (2010) J. Phys. Chem. A, 114, pp. 3256-3263

Albrecht, A.C., (1961) J. Mol. Spectrosc., 6, p. 84

Lampre, I., Markovitsi, D., Millie, P., (1997) J. Phys. Chem. A, 101, pp. 90-97

Barnett, R.N., Cleveland, C.L., Joy, A., Landman, U., Schuster, G.B., (2001) Science, 294, pp. 567-571

Hud, V., Plavec, J., The role of cations in determining quadruplex structure and stability (2006) Quadruplex Nucleic Acids, pp. 100-130. , In

Balasubramanian, S. Neidle, S. RSC Publishing: Cambridge, U.K

Davis, J. T., Spada, G. P., (2007) Chem. Soc. Rev., 36, pp. 296-313

Rochette, P. J., Brash, D. E., (2010) PLoS Genet., 6, p. 1000926

Mergny, J. L., Phan, A. T., Lacroix, L., (1998) FEBS Lett., 435, pp. 74-78

Mendez, M. A., Szalai, V. A., (2009) Biopolymers, 91, pp. 841-850

Dao, N. T., Haselsberger, R., Michel-Beyerle, M. E., Phan, A. T., (2011) FEBS Lett., 585, pp. 3969-3977

Miannay, F. A., Banyasz, A., Gustavsson, T., Markovitsi, D., (2009) J. Phys. Chem. C, 113, pp. 11760-11765

Schwalb, N. K., Temps, F., (2008) Science, 322, pp. 243-245

Middleton, C. T., De La Harpe, K., Su, C., Law, U. K., Crespo-Hern ndez, C. E., Kohler, B., (2009) Annu. Rev. Phys. Chem., 60, pp. 217-239

Doorley, G. W., McGovern, D. A., George, M. W., Towrie, M., Parker, A. W., Kelly, J. M., Quinn, S. J., (2009) Angew. Chem., Int. Ed., 48, pp. 123-127

Kwok, W. M., Ma, C. S., Phillips, D. L., (2009) J. Phys. Chem. B, 113, pp. 11527-11534

Bittner, E. R., (2006) J. Chem. Phys., 125, pp. 1-12. , 094909

Burin, A. L., Dickman, J. A., Uskov, D. B., Hebbard, C. F. F., Schatz, G. C., (2008) J. Chem. Phys., 129, p. 091102

Starikov, E. B., Cuniberti, G., Tanaka, S., (2009) J. Phys. Chem. B, 113, pp. 10428-10435

Lange, A. W., Herbert, J. M., (2009) J. Am. Chem. Soc., 131, pp. 3913-3922

Forman, S. L., Fettinger, J. C., Pieraccini, S., Gottareli, G., Davis, J. T., (2000) J. Am. Chem. Soc., 122, pp. 4060-4067

Kotlyar, A. B., Borovok, N., Molotsky, T., Cohen, H., Shapir, E., Porath, D., (2005) Adv. Mater., 17, pp. 1901-1905

Mergny, J. L., De Cian, A., Ghelab, A., Sacca, B., Lacroix, L., (2005) Nucleic Acids Res., 33, pp. 81-94

Xu, Q. W., Deng, H., Braunlin, W. H., (1993) Biochemistry, 32, pp. 13130-13137

Hud, N. V., Smith, F. W., Anet, F. A. L., Feigon, J., (1996) Biochemistry, 35, pp. 15383-15390

Miannay, F. A., Gustavsson, T., Banyasz, A., Markovitsi, D., (2010) J. Phys. Chem. A, 114, pp. 3256-3263

Albrecht, A. C., (1961) J. Mol. Spectrosc., 6, p. 84

Barnett, R. N., Cleveland, C. L., Joy, A., Landman, U., Schuster, G. B., (2001) Science, 294, pp. 567-571


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* Efficient UV-induced charge separation and recombination in an 8-oxoguanine-containing dinucleotide (67 views)
Zhang Y, Dood J, Beckstead AA, Li X-B, Nguyen KV, Burrows CJ, Improta R, Kohler B
Proc Natl Acad Sci U S A (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2014 Sep 12; 111(32): 11612-11617.

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1 Records (1 excluding Abstracts and Conferences).
Total impact factor: 9.674 (9.674 excluding Abstracts and Conferences).
Total 5-year impact factor: 10.563 (10.563 excluding Abstracts and Conferences).



Your bibliography query: (([btitle, keywords, abstract] CATION AND [btitle, keywords, abstract] EFFECTS AND [btitle, keywords, abstract] CHARGE AND [btitle, keywords, abstract] TRANSFER AND [btitle, keywords, abstract] EXCITED AND [btitle, keywords, abstract] STATE AND [btitle, keywords, abstract] ELECTRONIC)) AND NOT [id] = 10622



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