High Superoxide Dismutase Activity Of A Novel, Intramolecularly Imidazolato-Bridged Asymmetric Dicopper(ii) Species; Design, Synthesis, Structure And Magnetism Of Cu(ii) Complexes With A Mixed Pyrazole-Imidazole Donor Set
High Superoxide Dismutase Activity Of A Novel, Intramolecularly Imidazolato-Bridged Asymmetric Dicopper(ii) Species; Design, Synthesis, Structure And Magnetism Of Cu(ii) Complexes With A Mixed Pyrazole-Imidazole Donor Set(274 views visite) Tabbì G, Driessen WL, Reedijk J, Bonomo RP, Veldman N, Spek AL
Keywords Parole chiave: Not available. Non disponibili.
Affiliations Affiliazioni: Leiden Institute of Chemistry, Gorlaeus Laboratories, Leiden University, P. O. Box 9502, 2300 RA Leiden, Netherlands Department of Chemical Sciences, University of Catania, Viale A. Doria 6, 95125 Catania, Italy Bijvoet Ctr. for Biomol. Research, Utrecht University, Padualaan 8, 3584 CH Utrecht, Netherlands
References Riferimenti: Tainer, J. A., Getzoff, E. D., Richardson, J. S., Richardson, D. C., (1983) Nature, 306, p. 28
Fee, J. A., Briggs, R. G., (1975) Biochim. Biophys. Acta, 400, p. 439
Strotkamp, K. G., Lippard, S. J., (1982) Acc. Chem. Res., 15, p. 318
Gartner, A., Weser, U., (1986) Top. Curr. Chem., 132, p. 1
Murphy, B. P., (1993) Coord. Chem. Rev., 124, p. 63
Pierre, J. -L., Chautemps, P., Aif, S., Beguin, C., El Marzouki, A., Serratrice, G., Saint-Aman, E., Rey, P., (1995) J. Am. Chem. Soc., 117, p. 1965
Weser, U., Schubotz, L. M., Lengfelder, E., (1981) J. Mol. Catal., 13, p. 249
O'Young, C. -L., Dewan, J. C., Lilienthal, H. R., Lippard, S. J., (1978) J. Am. Chem. Soc., 100, p. 7291
Coughlin, P. K., Martin, A. E., Dewan, J. C., Watanabe, E., Bulkowski, J. E., Lehn, J. -L., Lippard, S. J., (1984) Inorg. Chem., 23, p. 1004
Coughlin, P. K., Lippard, S. J., (1984) Inorg. Chem., 23, p. 1446
Drew, M. G. B., Cairns, C., Lavery, A., Nelson, S. M., (1980) J. Chem. Soc., Chem. Commun., p. 1122
Drew, M. G. B., McCann, M., Nelson, S. M., (1981) J. Chem. Soc., Dalton Trans., p. 1868
Drew, M. G. B., Nelson, S. M., Reedijk, J., (1982) Inorg. Chim. Acta, 64, pp. L189
Sato, M., Ikeda, M., Nakaya, J., (1984) Inorg. Chim. Acta, 93, pp. L61
Cabrai, J., Cabrai, M. F., McCann, M., Nelson, S. M., (1984) Inorg. Chim. Acta, 86, pp. L15
Salata, C. A., Youinou, M. T., Burrows, C. J., (1989) J. Am. Chem. Soc., 111, p. 9278
Bonomo, R. P., Conte, E., Marchelli, R., Santoro, A. M., Tabbi, G., (1994) J. Inorg. Biochem., 53, p. 127
Bonomo, R. P., De Flora, A., Rizzarelli, E., Samoro, A. M., Tabbi, G., Tonetti, M., (1995) J. Inorg. Biochem., 59, p. 773
Bonomo, R. P., Marchelli, R., Tabbl, G., (1995) J. Inorg. Biochem., 60, p. 205
Kubota, S., Yang, J. T., (1984) Proc. Natl. Acad. Sci. U. S. A., 84, p. 3283
Costanzo, L. L., De Guidi, G., Giuffrida, S., Rizzarelli, E., Vecchio, G., (1993) J. Inorg. Biochem., 50, p. 273
Condorelli, G., Costanzo, L. L., De Guidi, G., Giuffrida, S., Rizzarelli, E., Vecchio, G., (1994) J. Inorg. Biochem, 54, p. 257
Leigh, M. J. T., Dwain, M. L., (1977) Synthesis, p. 459
Sorrell, T. N., Jameson, D. L., O'Connor, C. J., (1984) Inorg. Chem., 23, p. 190
Spek, A. L., (1990) Acta Crystallogr., A46, pp. C34
Beurskens, P. T., Admiraal, G., Beurskens, G., Bosman, W. P., Garcia-Granda, S., Gould, R. O., Smits, J. M. M., Smykalla, C., (1992) The DIRDIF Program System, , Technical report of the Crystallography Laboratory, University of Nijmegen: Nijmegen, The Netherlands
Sheldrick, G. M., (1993) SHELXL-93, , Program for Crystal Structure inement. University of G ttingen, Germany
Bleaney, B., Bowers, K. D., (1952) Proc. R. Soc. London, A, 214, p. 451
Bond, A. M., (1980) Modern Polarographic Methods in Analytical Chemistry, , Marcel Dekker Inc.: New York
Beauchamp, C., Fridovich, I., (1971) Anal. Biochem., 44, p. 276
Bielski, H. J., Shiue, G. G., Bajuk, S., (1980) J. Phys. Chem., 84, p. 830
Spek, A. L., (1996) WINPL96, Interactive Molecular Graphics and Calculations Program for Windows, , University of Utrecht, Utrecht
Matsumoto, K., Ooi, S., Nakao, Y., Mon, W., Nakahara, A., (1981) J. Chem. Soc., Dalton Trans., p. 2045
Haddad, M. S., Duester, E. N., Hendrickson, D. N., (1979) Inorg. Chem., 18, p. 141
Smith, T. D., Pilbrow, J. R., (1974) Coord. Chem. Rev., 13, p. 173
Schugar, H. J., (1983) Copper Coordination Chemistry: Biochemical and Inorganic Perspectives, , Karlin, K. D., Zubieta J., Eds.
Adenine Press: New York
Kolks, G., Lippard, S. J., (1984) Acta Crystallogr., C40, p. 261
Koolhaas, G. J. A. A., Driessen, W. L., Van Koningsbruggen, P., Reedijk, J., Spek, A. L., (1993) J. Chem. Soc., Dalton Trans., p. 3803
Knapp, S., Keenan, T. P., Zhang, X., Fikar, R., Potenza, J. A., Schugar, H. J., (1990) J. Am. Chem. Soc., 112, p. 3452
Ohkubo, S., Inoue, K., Tamaki, H., Ohba, M., Matsumoto, N., Okawa, H., Kida, S., (1992) Bull. Chem. Soc. Jpn., 65, p. 1603
Van Ooijen, J. A. C., Reedijk, J., Spek, A. L., (1979) J. Chem. Soc., Dalton Trans., p. 1183
Valle, G., Gonzalez, A. S., Ettorre, R., (1991) Acta Crystallogr., C47, p. 1392
M ller, E., Bernardinelli, G., Reedijk, J., (1996) Inorg. Chem., 35, p. 1952
Bouwman, E., Driessen, W. L., Reedijk, J., (1990) Coord. Chem. Rev., 104, p. 143
Van Albada, G. A., Haasnoot, J. G., Reedijk, J., Biagini-Cingi, M., Manotti-Lanfredi, A. M., Ugozzoli, F., (1995) Polyhedron, 14, p. 2467
Bol, J. E., Driessen, W. L., Reedijk, J., (1995) J. Chem. Soc., Chem. Commun., p. 1365
Tran, K. C., Battioni, J. P., Zimmerman, J. L., Bois, C., Koolhaas, G. J. A. A., Leduc, P., Mulliez, E., Chottard, J. C., (1994) Inorg. Chem., 33, p. 2808
Van Berkel, P. M., Driessen, W. L., Koolhaas, G. J. A. A., Reedijk, J., Sherrington, D. C., (1995) J. Chem. Soc., Chem. Commun., p. 147
Haanstra, W. G., Cabral, M. F., De O Cabral, J., Driessen, W. L., Reedijk, J., (1992) Inorg. Chem., 31, p. 3150
Driessen, W. L., Haanstra, W. G., Reedijk, J., (1992) Acta Crystallogr., C48, p. 1585
Bencini, A., Benelli, C., Gatteschi, D., Zanchini, C., (1986) Inorg. Chem., 25, p. 398
Haddad, M. S., Hendrickson, D. N., (1978) Inorg. Chem., 17, p. 2622
Chaudhuri, P., Karpensteinm, I., Winterm, M., Lengen, M., Butzlaff, C., Bill, E., Trautwein, A. X., Haupt, H. -J., (1993) Inorg. Chem., 32, p. 888
Hay, P. J., Thibeault, J. C., Huffman, R., (1975) J. Am. Chem. Soc., 97, p. 4884
Dewan, J. C., Lippard, S. J., (1980) Inorg. Chem., 19, p. 2079
Mao, Z. W., Chen, D., Tang, W. X., Yu, K. B., Liu, L., (1992) Polyhedron, 11, p. 191
Nishida, Y., Unoura, K., Watanabe, I., Yokomizo, T., Kato, Y., (1991) Inorg. Chim. Acta., 181, p. 141
Azab, H. A., Band, L., Borsari, M., Luchinat, C., Sola, M., Viezzoli, M. S., (1992) Inorg. Chem., 31, p. 4649
Ellerby, L. M., Cabelli, D. E., Graden, J. A., Valentine, J. S., (1996) J. Am. Chem. Soc., 118, pp. 6556-6561
Lu, Y., Roe, J. A., Bender, C. J., Peisach, J., Banci, L., Bertini, I., Gralla, E. B., Valentine, J. S., (1996) Inorg. Chem., 35, pp. 1692-1700
Spek, A.L., (1990) Acta Crystallogr., A46, pp. C34
Beurskens, P.T., Admiraal, G., Beurskens, G., Bosman, W.P., Garcia-Granda, S., Gould, R.O., Smits, J.M.M., Smykalla, C., (1992) The DIRDIF Program System, , Technical report of the Crystallography Laboratory, University of Nijmegen: Nijmegen, The Netherlands
Sheldrick, G.M., (1993) SHELXL-93, , Program for Crystal Structure inement. University of Göttingen, Germany
Bond, A.M., (1980) Modern Polarographic Methods in Analytical Chemistry, , Marcel Dekker Inc.: New York
Bielski, H.J., Shiue, G.G., Bajuk, S., (1980) J. Phys. Chem., 84, p. 830
Spek, A.L., (1996) WINPL96, Interactive Molecular Graphics and Calculations Program for Windows, , University of Utrecht, Utrecht
High Superoxide Dismutase Activity Of A Novel, Intramolecularly Imidazolato-Bridged Asymmetric Dicopper(ii) Species; Design, Synthesis, Structure And Magnetism Of Cu(ii) Complexes With A Mixed Pyrazole-Imidazole Donor Set
A new dinucleating ligand 1, 5-bis (l-pyrazolyl) -3- [bis (2-imidazolyl) methyl] azapentane (Hbpzbiap), containing pyrazoles and imidazoles has been designed and synthesized. The synthesis and characterization of the copper complexes with the ligand Hbpzbiap and its dehydronated form are described. This study is aimed at modeling the active site of copper-zinc Superoxide dismutase (SOD). Single crystals of the imidazolato-bridged complex [Cu2fbpzbiap) Cl3] (1) and non-imidazolato-bridged complex [Cu2 (Hbpzbiap) Cl4] (2) were obtained and their structures determined by X-ray diffraction. Both structures show two copper centers in two different coordination environments: a distorted square pyramid and a distorted tetrahedron. The Cu-nitrogen bond lengths range from 1. 919 (4) to 2. 039 (3) and are as expected. The copper-copper distances from 5. 566 (1) to 6. 104 (1) being only slightly shorter than that found in bovine erythrocyte SOD. Temperature-dependent magnetic susceptibility study of 1 shows antiferromagnetic behavior with -2J = 96 cm-1. From pH-dependent electron paramagnetic resonance and electronic spectra, [Cu2 (bpzbiap) Cl3] has been demonstrated to be stable over a quite wide pH range including the physiological pH values. A low concentration of this complex (1) catalyzes the dismutation of Superoxide at biological pH. Voltammetric studies indicate a quasi-reversible redox behavior in aqueous solution at pH 7. These results clearly indicate that complex 1 is a good model for Superoxide dismutase
High Superoxide Dismutase Activity Of A Novel, Intramolecularly Imidazolato-Bridged Asymmetric Dicopper(ii) Species; Design, Synthesis, Structure And Magnetism Of Cu(ii) Complexes With A Mixed Pyrazole-Imidazole Donor Set
High Superoxide Dismutase Activity Of A Novel, Intramolecularly Imidazolato-Bridged Asymmetric Dicopper(ii) Species; Design, Synthesis, Structure And Magnetism Of Cu(ii) Complexes With A Mixed Pyrazole-Imidazole Donor Set
Petraglia F, Singh AA, Carafa V, Nebbioso A, Conte M, Scisciola L, Valente S, Baldi A, Mandoli A, Petrizzi VB, Ingenito C, De Falco S, Cicatiello V, Apicella I, Janssen-megens EM, Kim B, Yi G, Logie C, Heath S, Ruvo M, Wierenga ATJ, Flicek P, Yaspo ML, Della Valle V, Bernard O, Tomassi S, Novellino E, Feoli A, Sbardella G, Gut I, Vellenga E, Stunnenberg HG, Mai A, Martens JHA, Altucci L * Combined HAT/EZH2 modulation leads to cancer-selective cell death(227 visite) Oncotarget (ISSN: 1949-2553electronic, 1949-2553linking), 2018 May 22; 9(39): 25630-25646. Impact Factor:5.008 DettagliEsporta in BibTeXEsporta in EndNote
Santulli G, Cipolletta E, Sorriento D, Del Giudice C, Anastasio A, Monaco S, Maione AS, Condorelli G, Puca A, Trimarco B, Illario M, Iaccarino G * CaMK4 gene deletion induces hypertension(287 visite) J Am Heart Assoc Journal Of The American Heart Association (ISSN: 2047-9980), 2012; 1(4): N/D-N/D. Impact Factor:2.882 DettagliEsporta in BibTeXEsporta in EndNote
589 Records (552 escludendo Abstract e Conferenze). Impact factor totale: 2235.936 (2133.953 escludendo Abstract e Conferenze). Impact factor a 5 anni totale: 2254.555 (2138.688 escludendo Abstract e Conferenze).
Last modified by Ultima modifica di Bruno Alfano on in data Sunday 12 July 2020, 13:15:15 274 views visite. Last view on Ultima visita in data Monday 29 March 2021, 0:03:39