(E)-2-Cyano-3-(5 Alpha-Piperidin-1-Yl-2, 2 Alpha-Bithien-5-Yl)acrylic Acid: A Fluorescent Probe For Detecting Prefibrillar Oligomers (240 visite)
European Journal Of Organic Chemistry (ISSN: 1434-193x), 2013 Jun; (18): 3635-3639.
Tipo di articolo: Journal Article,
Impact factor: 3.154, Impact factor a 5 anni: 3.001
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84879205787&partnerID=40&md5=92c0b615364f9ec0769ce819abc7e86a
Parole chiave: Aggregation, Atomic Force Microscopy, Electrophoresis, Fluorescent Probes, Heterocycles,
Affiliazioni:
*** IBB - CNR ***
Istituto di Biostrutture e Bioimmagini, Consiglio Nazionale Delle Ricerche (IBB-CNR), C/o Dipartimento di Scienze Chimiche, Viale A. Doria 6, 95125 Catania, Italy
Dipartimento di Fisica e Chimica, Università di Palermo, V.le delle Scienze, Ed. 17, 90100 Palermo, Italy
Riferimenti:
Lambert, M.P., Barlow, A.K., Chromy, B.A., Edwards, C., Freed, R., Liosatos, M., Morgan, T.E., Klein, W.L., (1998) Proc. Natl. Acad. Sci. USA, 95, pp. 6448-645
Sousa, M.M., Cardoso, I., Fernandes, R., Guimaraes, A., Saraiva, M.J., (2001) Am. J. Pathol., 159, pp. 1993-2000
Giuffrida, M.L., Caraci, F., Pignataro, B., Cataldo, S., De Bona, P., Bruno, V., Molinaro, G., Copani, A., (2009) J. Neurosci., 29, pp. 10582-10587
Kayed, R., Head, E., Thompson, J.L., McIntire, T.M., Milton, S.C., Cotman, C.W., Glabe, C.G., (2003) Science, 300, pp. 486-489
Walsh, D.M., Klyubin, I., Fadeeva, J.V., Cullen, W.K., Anwyl, R., Wolfe, M.S., Rowan, M.J., Selkoe, D.J., (2002) Nature, 416, pp. 535-539
Reinke, A.A., Abulwerdi, G.A., Gestwicki, J.E., (2010) ChemBioChem, 11, pp. 1889-1895
Levine Iii, H., (2008) Protein Sci., 2, pp. 404-410
Matsuoka, S., Murai, M., Yamazaki, T., Inoue, M., (2012) Org. Biomol. Chem., 10, pp. 5787-5790
Amdursky, N., Erez, Y., Huppert, D., (2012) Acc. Chem. Res., 45, pp. 1548-1557
Babenko, V., Dzwolak, W., (2011) Chem. Commun., 47, pp. 10686-10688
Klunk, W.E., Wang, Y., Huang, G.F., Debnath, M.L., Holt, D.P., Mathis, C.A., (2001) Life Sci., 69, pp. 1471-1484
Sabate, R., Lascu, I., Saupe, S.J., (2008) J. Struct. Biol., 162, pp. 387-396
Lindgren, M., Hammarström, P., (2010) FEBS J., 277, pp. 1380-1388
Lee, J., Culyba, E.K., Powers, E.T., Kelly, J.W., (2011) Nat. Chem. Biol., 7, pp. 602-609
Damico, M., Di Carlo, M.G., Groenning, M., Militello, V., Vetri, V., Leone, M., (2012) J. Phys. Chem. Lett., 3, pp. 1596-1601
Nesterov, E.E., Skoch, J., Hyman, B.T., Klunk, W.E., Bacskai, B.J., Swager, T.M., (2005) Angew. Chem., 117, p. 5588
(2005) Angew. Chem. Int. Ed., 44, pp. 5452-5456
Marek, P., Gupta, R., Raleigh, D.P., (2008) ChemBioChem, 9, pp. 1372-1374
Celej, M.S., Jares-Erijman, E.A., Jovin, T.M., (2008) Biophys. J., 94, pp. 4867-4879
Aslund, A., Sigurdson, C.J., Klingstedt, T., Grathwohl, S., Bolmont, T., Dickstein, D.L., Glimsdal, E., Nilsson, K.P., (2009) ACS Chem. Biol., 4, pp. 673-684
Mishra, R., Sjolander, D., Hammarström, P., (2011) Mol. BioSyst., 7, pp. 1232-1240
Hammarström, P., Simon, R., Nystrom, S., Konradsson, P., Aslund, A., Nilsson, K.P.R., (2010) Biochemistry, 49, pp. 6838-6845
Kumar, M., Sarkar, N., Dubey, V.K., (2012) Protein Pept. Lett., 19, pp. 826-831
Krebs, M.R., Wilkins, D.K., Chung, E.W., Pitkeathly, M.C., Chamberlain, A.K., Zurdo, J., Robinson, C.V., Dobson, C.M., (2000) J. Mol. Biol., 300, pp. 541-549
Goda, S., Takano, K., Yamagata, Y., Nagata, R., Akutsu, H., Maki, S., Namba, K., Yutani, K., (2000) Protein Sci., 9, pp. 369-375
Arnaudov, L.N., De Vries, R., (2005) Biophys. J., 88, pp. 515-526
Hill, S.E., Miti, T., Richmond, T., Muschol, M., (2011) PLoS ONE, 6, pp. e18171. , [DOI: 10.1371/journal.pone.0018171]
Hill, S.E., Robinson, J., Matthews, G., Muschol, M., (2009) Biophys. J., 96, pp. 3781-3790
Vieira, M.N.N., Forny-Germano, L., Saraiva, L.M., Sebollela, A., Blanco Martinez, A.M., Houzel, J.C., De Felice, F.G., Ferreira, S.T., (2007) J. Neurochem., 103, pp. 736-748
Fortuna, C.G., Bonaccorso, C., Qamar, F., Anu, A., Ledoux, I., Musumarra, G., (2011) Org. Biomol. Chem., 9, pp. 1608-1613
Musumarra, G., Ballistreri, F.P., (1981) Chem. Scr., 18, pp. 209-213
Ballistreri, F.P., Musumarra, G., Scarlata, G., (1981) Chem. Scr., 18, pp. 214-216
Vernaglia, B.A., Huang, J., Clark, E.D., (2004) Biomacromolecules, 5, pp. 1362-1370
Frare, E., Polverino De Laureto, P., Zurdo, J., Dobson, C.M., Fontana, A., (2004) J. Mol. Biol., 340, pp. 1153-1165
Parmar, A.S., Muschol, M., (2009) Biophys. J., 97, pp. 590-598
Voets, I.K., Cruz, W.A., Moitzi, C., Lindner, P., Arêas, E.P.G., Schurtenberger, P., (2010) J. Phys. Chem. B, 114, pp. 11875-11883
Lambert, M. P., Barlow, A. K., Chromy, B. A., Edwards, C., Freed, R., Liosatos, M., Morgan, T. E., Klein, W. L., (1998) Proc. Natl. Acad. Sci. USA, 95, pp. 6448-645
Sousa, M. M., Cardoso, I., Fernandes, R., Guimaraes, A., Saraiva, M. J., (2001) Am. J. Pathol., 159, pp. 1993-2000
Giuffrida, M. L., Caraci, F., Pignataro, B., Cataldo, S., De Bona, P., Bruno, V., Molinaro, G., Copani, A., (2009) J. Neurosci., 29, pp. 10582-10587
Walsh, D. M., Klyubin, I., Fadeeva, J. V., Cullen, W. K., Anwyl, R., Wolfe, M. S., Rowan, M. J., Selkoe, D. J., (2002) Nature, 416, pp. 535-539
Reinke, A. A., Abulwerdi, G. A., Gestwicki, J. E., (2010) ChemBioChem, 11, pp. 1889-1895
Klunk, W. E., Wang, Y., Huang, G. F., Debnath, M. L., Holt, D. P., Mathis, C. A., (2001) Life Sci., 69, pp. 1471-1484
Lee, J., Culyba, E. K., Powers, E. T., Kelly, J. W., (2011) Nat. Chem. Biol., 7, pp. 602-609
Nesterov, E. E., Skoch, J., Hyman, B. T., Klunk, W. E., Bacskai, B. J., Swager, T. M., (2005) Angew. Chem., 117, p. 5588
Celej, M. S., Jares-Erijman, E. A., Jovin, T. M., (2008) Biophys. J., 94, pp. 4867-4879
Hammarstr m, P., Simon, R., Nystrom, S., Konradsson, P., Aslund, A., Nilsson, K. P. R., (2010) Biochemistry, 49, pp. 6838-6845
Krebs, M. R., Wilkins, D. K., Chung, E. W., Pitkeathly, M. C., Chamberlain, A. K., Zurdo, J., Robinson, C. V., Dobson, C. M., (2000) J. Mol. Biol., 300, pp. 541-549
Arnaudov, L. N., De Vries, R., (2005) Biophys. J., 88, pp. 515-526
Hill, S. E., Miti, T., Richmond, T., Muschol, M., (2011) PLoS ONE, 6, pp. e18171. , [DOI: 10. 1371/journal. pone. 0018171]
Hill, S. E., Robinson, J., Matthews, G., Muschol, M., (2009) Biophys. J., 96, pp. 3781-3790
Vieira, M. N. N., Forny-Germano, L., Saraiva, L. M., Sebollela, A., Blanco Martinez, A. M., Houzel, J. C., De Felice, F. G., Ferreira, S. T., (2007) J. Neurochem., 103, pp. 736-748
Fortuna, C. G., Bonaccorso, C., Qamar, F., Anu, A., Ledoux, I., Musumarra, G., (2011) Org. Biomol. Chem., 9, pp. 1608-1613
Vernaglia, B. A., Huang, J., Clark, E. D., (2004) Biomacromolecules, 5, pp. 1362-1370
Parmar, A. S., Muschol, M., (2009) Biophys. J., 97, pp. 590-598
Voets, I. K., Cruz, W. A., Moitzi, C., Lindner, P., Ar as, E. P. G., Schurtenberger, P., (2010) J. Phys. Chem. B, 114, pp. 11875-11883
European Journal Of Organic Chemistry (ISSN: 1434-193x), 2013 Jun; (18): 3635-3639.
Tipo di articolo: Journal Article,
Impact factor: 3.154, Impact factor a 5 anni: 3.001
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84879205787&partnerID=40&md5=92c0b615364f9ec0769ce819abc7e86a
Parole chiave: Aggregation, Atomic Force Microscopy, Electrophoresis, Fluorescent Probes, Heterocycles,
Affiliazioni:
*** IBB - CNR ***
Istituto di Biostrutture e Bioimmagini, Consiglio Nazionale Delle Ricerche (IBB-CNR), C/o Dipartimento di Scienze Chimiche, Viale A. Doria 6, 95125 Catania, Italy
Dipartimento di Fisica e Chimica, Università di Palermo, V.le delle Scienze, Ed. 17, 90100 Palermo, Italy
Riferimenti:
Lambert, M.P., Barlow, A.K., Chromy, B.A., Edwards, C., Freed, R., Liosatos, M., Morgan, T.E., Klein, W.L., (1998) Proc. Natl. Acad. Sci. USA, 95, pp. 6448-645
Sousa, M.M., Cardoso, I., Fernandes, R., Guimaraes, A., Saraiva, M.J., (2001) Am. J. Pathol., 159, pp. 1993-2000
Giuffrida, M.L., Caraci, F., Pignataro, B., Cataldo, S., De Bona, P., Bruno, V., Molinaro, G., Copani, A., (2009) J. Neurosci., 29, pp. 10582-10587
Kayed, R., Head, E., Thompson, J.L., McIntire, T.M., Milton, S.C., Cotman, C.W., Glabe, C.G., (2003) Science, 300, pp. 486-489
Walsh, D.M., Klyubin, I., Fadeeva, J.V., Cullen, W.K., Anwyl, R., Wolfe, M.S., Rowan, M.J., Selkoe, D.J., (2002) Nature, 416, pp. 535-539
Reinke, A.A., Abulwerdi, G.A., Gestwicki, J.E., (2010) ChemBioChem, 11, pp. 1889-1895
Levine Iii, H., (2008) Protein Sci., 2, pp. 404-410
Matsuoka, S., Murai, M., Yamazaki, T., Inoue, M., (2012) Org. Biomol. Chem., 10, pp. 5787-5790
Amdursky, N., Erez, Y., Huppert, D., (2012) Acc. Chem. Res., 45, pp. 1548-1557
Babenko, V., Dzwolak, W., (2011) Chem. Commun., 47, pp. 10686-10688
Klunk, W.E., Wang, Y., Huang, G.F., Debnath, M.L., Holt, D.P., Mathis, C.A., (2001) Life Sci., 69, pp. 1471-1484
Sabate, R., Lascu, I., Saupe, S.J., (2008) J. Struct. Biol., 162, pp. 387-396
Lindgren, M., Hammarström, P., (2010) FEBS J., 277, pp. 1380-1388
Lee, J., Culyba, E.K., Powers, E.T., Kelly, J.W., (2011) Nat. Chem. Biol., 7, pp. 602-609
Damico, M., Di Carlo, M.G., Groenning, M., Militello, V., Vetri, V., Leone, M., (2012) J. Phys. Chem. Lett., 3, pp. 1596-1601
Nesterov, E.E., Skoch, J., Hyman, B.T., Klunk, W.E., Bacskai, B.J., Swager, T.M., (2005) Angew. Chem., 117, p. 5588
(2005) Angew. Chem. Int. Ed., 44, pp. 5452-5456
Marek, P., Gupta, R., Raleigh, D.P., (2008) ChemBioChem, 9, pp. 1372-1374
Celej, M.S., Jares-Erijman, E.A., Jovin, T.M., (2008) Biophys. J., 94, pp. 4867-4879
Aslund, A., Sigurdson, C.J., Klingstedt, T., Grathwohl, S., Bolmont, T., Dickstein, D.L., Glimsdal, E., Nilsson, K.P., (2009) ACS Chem. Biol., 4, pp. 673-684
Mishra, R., Sjolander, D., Hammarström, P., (2011) Mol. BioSyst., 7, pp. 1232-1240
Hammarström, P., Simon, R., Nystrom, S., Konradsson, P., Aslund, A., Nilsson, K.P.R., (2010) Biochemistry, 49, pp. 6838-6845
Kumar, M., Sarkar, N., Dubey, V.K., (2012) Protein Pept. Lett., 19, pp. 826-831
Krebs, M.R., Wilkins, D.K., Chung, E.W., Pitkeathly, M.C., Chamberlain, A.K., Zurdo, J., Robinson, C.V., Dobson, C.M., (2000) J. Mol. Biol., 300, pp. 541-549
Goda, S., Takano, K., Yamagata, Y., Nagata, R., Akutsu, H., Maki, S., Namba, K., Yutani, K., (2000) Protein Sci., 9, pp. 369-375
Arnaudov, L.N., De Vries, R., (2005) Biophys. J., 88, pp. 515-526
Hill, S.E., Miti, T., Richmond, T., Muschol, M., (2011) PLoS ONE, 6, pp. e18171. , [DOI: 10.1371/journal.pone.0018171]
Hill, S.E., Robinson, J., Matthews, G., Muschol, M., (2009) Biophys. J., 96, pp. 3781-3790
Vieira, M.N.N., Forny-Germano, L., Saraiva, L.M., Sebollela, A., Blanco Martinez, A.M., Houzel, J.C., De Felice, F.G., Ferreira, S.T., (2007) J. Neurochem., 103, pp. 736-748
Fortuna, C.G., Bonaccorso, C., Qamar, F., Anu, A., Ledoux, I., Musumarra, G., (2011) Org. Biomol. Chem., 9, pp. 1608-1613
Musumarra, G., Ballistreri, F.P., (1981) Chem. Scr., 18, pp. 209-213
Ballistreri, F.P., Musumarra, G., Scarlata, G., (1981) Chem. Scr., 18, pp. 214-216
Vernaglia, B.A., Huang, J., Clark, E.D., (2004) Biomacromolecules, 5, pp. 1362-1370
Frare, E., Polverino De Laureto, P., Zurdo, J., Dobson, C.M., Fontana, A., (2004) J. Mol. Biol., 340, pp. 1153-1165
Parmar, A.S., Muschol, M., (2009) Biophys. J., 97, pp. 590-598
Voets, I.K., Cruz, W.A., Moitzi, C., Lindner, P., Arêas, E.P.G., Schurtenberger, P., (2010) J. Phys. Chem. B, 114, pp. 11875-11883
Lambert, M. P., Barlow, A. K., Chromy, B. A., Edwards, C., Freed, R., Liosatos, M., Morgan, T. E., Klein, W. L., (1998) Proc. Natl. Acad. Sci. USA, 95, pp. 6448-645
Sousa, M. M., Cardoso, I., Fernandes, R., Guimaraes, A., Saraiva, M. J., (2001) Am. J. Pathol., 159, pp. 1993-2000
Giuffrida, M. L., Caraci, F., Pignataro, B., Cataldo, S., De Bona, P., Bruno, V., Molinaro, G., Copani, A., (2009) J. Neurosci., 29, pp. 10582-10587
Walsh, D. M., Klyubin, I., Fadeeva, J. V., Cullen, W. K., Anwyl, R., Wolfe, M. S., Rowan, M. J., Selkoe, D. J., (2002) Nature, 416, pp. 535-539
Reinke, A. A., Abulwerdi, G. A., Gestwicki, J. E., (2010) ChemBioChem, 11, pp. 1889-1895
Klunk, W. E., Wang, Y., Huang, G. F., Debnath, M. L., Holt, D. P., Mathis, C. A., (2001) Life Sci., 69, pp. 1471-1484
Lee, J., Culyba, E. K., Powers, E. T., Kelly, J. W., (2011) Nat. Chem. Biol., 7, pp. 602-609
Nesterov, E. E., Skoch, J., Hyman, B. T., Klunk, W. E., Bacskai, B. J., Swager, T. M., (2005) Angew. Chem., 117, p. 5588
Celej, M. S., Jares-Erijman, E. A., Jovin, T. M., (2008) Biophys. J., 94, pp. 4867-4879
Hammarstr m, P., Simon, R., Nystrom, S., Konradsson, P., Aslund, A., Nilsson, K. P. R., (2010) Biochemistry, 49, pp. 6838-6845
Krebs, M. R., Wilkins, D. K., Chung, E. W., Pitkeathly, M. C., Chamberlain, A. K., Zurdo, J., Robinson, C. V., Dobson, C. M., (2000) J. Mol. Biol., 300, pp. 541-549
Arnaudov, L. N., De Vries, R., (2005) Biophys. J., 88, pp. 515-526
Hill, S. E., Miti, T., Richmond, T., Muschol, M., (2011) PLoS ONE, 6, pp. e18171. , [DOI: 10. 1371/journal. pone. 0018171]
Hill, S. E., Robinson, J., Matthews, G., Muschol, M., (2009) Biophys. J., 96, pp. 3781-3790
Vieira, M. N. N., Forny-Germano, L., Saraiva, L. M., Sebollela, A., Blanco Martinez, A. M., Houzel, J. C., De Felice, F. G., Ferreira, S. T., (2007) J. Neurochem., 103, pp. 736-748
Fortuna, C. G., Bonaccorso, C., Qamar, F., Anu, A., Ledoux, I., Musumarra, G., (2011) Org. Biomol. Chem., 9, pp. 1608-1613
Vernaglia, B. A., Huang, J., Clark, E. D., (2004) Biomacromolecules, 5, pp. 1362-1370
Parmar, A. S., Muschol, M., (2009) Biophys. J., 97, pp. 590-598
Voets, I. K., Cruz, W. A., Moitzi, C., Lindner, P., Ar as, E. P. G., Schurtenberger, P., (2010) J. Phys. Chem. B, 114, pp. 11875-11883
The synthesis of (E)-2-cyano-3-(5′-piperidin-1-yl-2,2′-bithien- 5-yl)acrylic acid, a novel amyloid aggregation fluorescent probe, is reported. This new probe is able to monitor soluble oligomeric aggregates after 24 h, at which time Thioflavin T emission, commonly used to monitor amyloid fibril formation, remains unchanged. Atomic force microscopy, native polyacrylamide gel electrophoresis, and dynamic light scattering confirm that the earlier stages of aggregation are prefibrillar oligomeric species not possessing the amyloid structure. This new molecular scaffold expands the toolbox of fluorescent probes for the identification of prefibrillar oligomers, which is needed in studies aimed at the early detection of the soluble toxic aggregates that characterize the so-called protein misfolding diseases. (E)-2-Cyano-3-(5′-piperidin-1- yl-2,2′-bithien-5-yl)acrylic acid (p-TTCNAc) can be conveniently used as a fluorescent probe to identify prefibrillar oligomers of hen egg white lysozyme not detected by Thioflavin-T (ThT). Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
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* Tau-peptide fragments and their copper(II) complexes: Effects on Amyloid-beta aggregation (176 visite)
Inorganica Chimica Acta, 2017 Sep; N/D: N/D-N/D.
Impact Factor: 2.002
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Picone D, Donnarumma F, Ferraro G, Gotte G, Fagagnini A, Butera G, Donadelli M, Merlino A
* A comparison study on RNase A oligomerization induced by cisplatin, carboplatin and oxaliplatin (136 visite)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2017 Aug; 173: 105-112.
Impact Factor: 3.063
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Musumeci D, Roviello GN, Rigione G, Capasso D, Di Gaetano S, Riccardi C, Roviello V, Montesarchio D
* Benzodifuran derivatives as potential antiproliferative agents: possible correlation between the bioactivity and their aggregation properties (263 visite)
Chempluschem, 2017; 82: 251-260.
Impact Factor: 2.8
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Grasso GI, Bellia F, Arena G, Satriano C, Vecchio G, Rizzarelli E
* Multitarget trehalose-carnosine conjugates inhibit Aβ aggregation, tune copper(II) activity and decrease acrolein toxicity (212 visite)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 0223-5234linking), 2017; 135: 447-457.
Impact Factor: 4.816
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Oliveri V, Bellia F, Vecchio G
* Structural Isomers of Cyclodextrin-Bearing IOX1 Compound as Inhibitors of Aβ Aggregation (93 visite)
Chemistryselect (ISSN: 2365-6549), 2017; 2(2): 655-659.
Impact Factor: 1.505
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Simoni E, Caporaso R, Bergamini C, Fiori J, Fato R, Miszta P, Filipek S, Caraci F, Giuffrida ML, Andrisano V, Minarini A, Bartolini M, Rosini M
* Polyamine Conjugation as a Promising Strategy To Target Amyloid Aggregation in the Framework of Alzheimer's Disease (179 visite)
Acs Med Chem Lett (ISSN: 1948-5875), 2016 Sep 26; 7(12): 1145-1150.
Impact Factor: 3.746
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Scognamiglio PL, Di Natale C, Leone M, Cascella R, Cecchi C, Lirussi L, Antoniali G, Riccardi D, Morelli G, Tell G, Chiti F, Marasco D
* Destabilisation, aggregation, toxicity and cytosolic mislocalisation of nucleophosmin regions associated with acute myeloid leukemia (204 visite)
Oncotarget (ISSN: 1949-2553, 1949-2553electronic), 2016 Aug 1; N/D: N/D-N/D.
Impact Factor: 5.168
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Giglio V, Bellia F, Oliveri V, Vecchio G
* Aminocyclodextrin Oligomers as Protective Agents of Protein Aggregation (220 visite)
Chempluschem, 2016; 81(7): 660-665.
Impact Factor: 0
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Ribaldone DG, Fagoonee S, Hickman I, Altruda F, Saracco GM, Pellicano R
* Helicobacter pylori infection and ischemic heart disease: Could experimental data lead to clinical studies? (100 visite)
Minerva Cardioangiol (ISSN: 0026-4725), 2016; 64(6): 686-696.
Impact Factor: 0.695
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Del Giudice R, Arciello A, Itri F, Merlino A, Monti M, Buonanno M, Penco A, Canetti D, Petruk G, Monti SM, Relini A, Pucci P, Piccoli R, Monti DM
* Protein conformational perturbations in hereditary amyloidosis: Differential impact of single point mutations in ApoAI amyloidogenic variants (203 visite)
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2016; 1860(2): 434-444.
Impact Factor: 5.476
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Palladino P, Aura AM, Spoto G
* Surface plasmon resonance for the label-free detection of Alzheimer's β-amyloid peptide aggregation (249 visite)
Anal Bioanal Chem (ISSN: 1618-2642), 2016; 408(3): 849-854.
Impact Factor: 3.431
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Trusso Sfrazzetto G, Satriano C, Tomaselli GA, Rizzarelli E
* Synthetic fluorescent probes to map metallostasis and intracellular fate of zinc and copper (162 visite)
Coord Chem Rev (ISSN: 0010-8545), 2016; 311: 125-167.
Impact Factor: 13.324
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Oliveri V, Bellia F, Grasso GI, Pietropaolo A, Vecchio G
* Trehalose-8-hydroxyquinoline conjugates as antioxidant modulators of Aβ aggregation (222 visite)
Rsc Adv (ISSN: 2046-2069), 2016; 6(53): 47229-47236.
Impact Factor: 3.108
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Caraci F, Pappalardo G, Basile L, Giuffrida A, Copani A, Tosto R, Sinopoli A, Giuffrida ML, Pirrone E, Drago F, Pignatello R, Guccione S
* Neuroprotective effects of the monoamine oxidase inhibitor Tranylcypromine and its amide derivatives against Abeta(1-42)-induced toxicity (325 visite)
Eur J Pharmacol (ISSN: 0014-2999), 2015 Jul 7; 764: 256-263.
Impact Factor: 2.73
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GrassoG, Satriano C, Milardi D
* A neglected modulator of insulin-degrading enzyme activity and conformation: The pH (217 visite)
Biophys Chem (ISSN: 0301-4622, 0301-4622linking), 2015; 203-204: 33-40.
Impact Factor: 2.363
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Lanza V, D'Agata R, Iacono G, Bellia F, Spoto G, Vecchio G
* Cyclam glycoconjugates as lectin ligands and protective agents of metal-induced amyloid aggregation (255 visite)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2015; 153: 377-382.
Impact Factor: 3.205
Dettagli Esporta in BibTeX Esporta in EndNote
Oliveri V, Bellia F, Vecchio G
* Cyclodextrin 3-functionalized with 8-hydroxyquinoline as an antioxidant inhibitor of metal-induced amyloid aggregation (218 visite)
Chempluschem (ISSN: 2192-6506), 2015; 80(4): 762-770.
Impact Factor: 2.836
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Speciale I, Paciello I, Fazio LL, Sturiale L, Palmigiano A, Lanzetta R, Parrilli M, Garozzo D, Lemaitre B, Bernardini ML, Molinaro A, De Castro C
* Determination of the structure of the O-antigen and the lipid A from the entomopathogenic bacterium Pseudomonas entomophila lipopolysaccharide along with its immunological properties (155 visite)
Carbohyd Res (ISSN: 0008-6215), 2015; 412: 20-27.
Impact Factor: 1.817
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Pietropaolo A, Satriano C, Strano G, La Mendola D, Rizzarelli E
* Different zinc(II) complex species and binding modes at Aβ N-terminus drive distinct long range cross-talks in the Aβ monomers (190 visite)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2015; N/D: N/D-N/D.
Impact Factor: 3.205
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Di Lorenzo F, Silipo A, Bianconi I, Lore' NI, Scamporrino A, Sturiale L, Garozzo D, Lanzetta R, Parrilli M, Bragonzi A, Molinaro A
* Persistent cystic fibrosis isolate Pseudomonas aeruginosa strain RP73 exhibits an under-acylated LPS structure responsible of its low inflammatory activity (164 visite)
Mol Immunol (ISSN: 0161-5890), 2015; 63(2): 166-175.
Impact Factor: 3.375
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Picone D, Donnarumma F, Ferraro G, Russo Krauss I, Fagagnini A, Gotte G, Merlino A
* Platinated oligomers of bovine pancreatic ribonuclease: Structure and stability (207 visite)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2015; 146: 37-43.
Impact Factor: 3.205
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Lolicato F, Raudino A, Milardi D, La Rosa C
* Resveratrol interferes with the aggregation of membrane-bound human-IAPP: A molecular dynamics study (292 visite)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 0223-5234linking), 2015; 92: 876-881.
Impact Factor: 3.902
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Oliveri V, Grasso GI, Bellia F, Attanasio F, Viale M, Vecchio G
* Soluble sugar-based quinoline derivatives as new antioxidant modulators of metal-induced amyloid aggregation (292 visite)
Inorg Chem (ISSN: 0020-1669, 1520-510x), 2015; 54(6): 2591-2602.
Impact Factor: 4.82
Dettagli Esporta in BibTeX Esporta in EndNote
Oliveri V, Bellia F, Pietropaolo A, Vecchio G
* Unusual Cyclodextrin Derivatives as a New Avenue to Modulate Self- and Metal-Induced Aβ Aggregation (232 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2015; 21(40): 14047-14059.
Impact Factor: 5.771
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Altieri F, Di Stadio CS, Severino V, Sandomenico A, Minopoli G, Miselli G, Di Maro A, Ruvo M, Chambery A, Quagliariello V, Masullo M, Rippa E, Arcari P
* Anti-amyloidogenic property of human gastrokine (281 visite)
Biochimie (ISSN: 0300-9084, 1638-6183, 0300-9084linking), 2014 Nov; 106C: 91-100.
Impact Factor: 2.963
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Sinopoli A, Magri A, Milardi D, Pappalardo M, Pucci P, Flagiello A, Titman JJ, Nicoletti VG, Caruso G, Pappalardo G, GrassoG
* The role of copper(II) in the aggregation of human amylin (273 visite)
Metallomics (ISSN: 1756-5901, 1756-591x), 2014 Oct; 6(10): 1841-1852.
Impact Factor: 3.585
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Saghyan AS, Simonyan HM, Petrosyan SG, Geolchanyan AV, Roviello GN, Musumeci D, Roviello V
* Thiophenyl-substituted triazolyl-thione L-alanine: asymmetric synthesis, aggregation and biological properties (282 visite)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2014 Oct; 46(10): 2325-2332.
Impact Factor: 3.293
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Oliveri V, Attanasio F, Puglisi A, Spencer J, Sgarlata C, Vecchio G
* Multifunctional 8-hydroxyquinoline-appended cyclodextrins as new inhibitors of metal-induced protein aggregation (289 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2014 Jul 14; 20(29): 8954-8964.
Impact Factor: 5.731
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Ruggiero A, Dattelbaum JD, Staiano M, Berisio R, D'Auria S, Vitagliano L
* A loose domain swapping organization confers a remarkable stability to the dimeric structure of the arginine binding protein from Thermotoga maritima (195 visite)
Plosone (ISSN: 1932-6203, 1932-6203electronic), 2014 May 15; 9(5): e96560-e96560.
Impact Factor: 3.234
Dettagli Esporta in BibTeX Esporta in EndNote
Grasso GI, Arena G, Bellia F, Rizzarelli E, Vecchio G
* Copper(II)-chelating homocarnosine glycoconjugate as a new multifunctional compound (189 visite)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2014 Feb; 131: 56-63.
Impact Factor: 3.444
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Orlandini S, Pasquini B, Gotti R, Giuffrida A, Paternostro F, Furlanetto S
* Analytical quality by design in the development of a cyclodextrin-modified capillary electrophoresis method for the assay of metformin and its related substances (34 visite)
Electrophoresis (ISSN: 0173-0835), 2014; 35(17): 2538-2545.
Impact Factor: 3.028
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Villari V, Attanasio F, Micali N
* Control of the structural stability of α-crystallin under thermal and chemical stress: The role of carnosine (229 visite)
J Phys Chem B (ISSN: 1520-6106, 1520-5207), 2014; 118(47): 13770-13776.
Impact Factor: 3.302
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Chi M-C, Lo Y-H, Chen Y-Y, Lin L-L, Merlino A
* γ-Glutamyl transpeptidase architecture: Effect of extra sequence deletion on autoprocessing, structure and stability of the protein from Bacillus licheniformis (167 visite)
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2014; 1844(12): 2290-2297.
Impact Factor: 4.882
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Giuffrida A, Maccarrone G, Cucinotta V, Orlandini S, Contino A
* Recent advances in chiral separation of amino acids using capillary electromigration techniques (35 visite)
J Chromatogr A (ISSN: 0021-9673), 2014; 1363: 41-50.
Impact Factor: 4.169
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Milardi D, Sciacca MF, Randazzo L, Raudino A, La Rosa C
* The role of calcium, lipid membranes and islet amyloid polypeptide in the onset of type 2 diabetes: Innocent bystanders or partners in a crime? (219 visite)
Front Endocrinol (ISSN: 1664-2392, 1664-2392linking, 1664-2392print), 2014; 5(DEC): 216-216.
Impact Factor: 3.675
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Pica A, Merlino A, Buell AK, Knowles TJ, Pizzo E, D'Alessio G, Sica F, Mazzarella L
* Three-dimensional domain swapping and supramolecular protein assembly: insights from the X-ray structure of a dimeric swapped variant of human pancreatic RNase (182 visite)
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2013 Oct; 69: 2116-2123.
Impact Factor: 7.232
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Galdiero S, Falanga A, Cantisani M, Vitiello M, Morelli G, Galdiero M
* Peptide-Lipid Interactions: Experiments and Applications (305 visite)
Int J Mol Sc (ISSN: 1422-0067, 1661-6596, 1422-0067electronic), 2013 Sep; 14(9): 18758-18789.
Impact Factor: 2.339
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Sandomenico A, Severino V, Chambery A, Focà A, Focà G, Farina C, Ruvo M
* A Comparative Structural and Bioanalytical Study of IVIG Clinical Lots (178 visite)
Mol Biotechnol (ISSN: 1073-6085, 1559-0305electronic, 1073-6085linking), 2013 Jul; 54(3): 983-995.
Impact Factor: 2.275
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Nande R, Greco A, Gossman MS, Lopez JP, Claudio L, Salvatore M, Brunetti A, Denvir J, Howard CM, Claudio PP
* Microbubble-assisted p53, RB, and p130 gene transfer in combination with radiation therapy in prostate cancer (249 visite)
Current Gene Therapy (ISSN: 1875-5631, 1566-5232), 2013 Jun 1; 13(3): 163-174.
Impact Factor: 4.906
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De Simonea A, Stanzione F, Marasco D, Vitagliano L, Esposito L
* The Intrinsic Stability Of The Human Prion Beta-Sheet Region Investigated By Molecular Dynamics (249 visite)
Journal Of Biomolecular Structure & Dynamics, 2013 May 1; 31(5): 441-452.
Impact Factor: 2.983
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Hunger K, Buschhaus L, Biemann L, Braun M, Kovalenko S, Improta R, Kleinermanns K
* UV-light-induced hydrogen transfer in guanosine-guanosine aggregates (196 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2013 Apr; 19(17): 5425-5431.
Impact Factor: 5.696
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Attanasio F, Convertino M, Magno A, Caflisch A, Corazza A, Haridas H, Esposito G, Cataldo S, Pignataro B, Milardi D, Rizzarelli E
* Carnosine Inhibits Abeta(42) Aggregation By Perturbing The H-Bond Network In And Around The Central Hydrophobic Cluster (269 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2013 Mar 18; 14(5): 583-592.
Impact Factor: 3.06
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Sciacca MFM, Milardi D, Messina GML, Marletta G, Brender JR, Ramamoorthy A, La Rosa C
* Cations as switches of amyloid-mediated membrane disruption mechanisms: Calcium and IAPP (223 visite)
Biophysical Journal (ISSN: 0006-3495, 1542-0086), 2013 Jan 8; 104(1): 173-184.
Impact Factor: 3.832
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Causa F, Della Moglie R, Iaccino E, Mimmi S, Marasco D, Scognamiglio PL, Battista E, Palmieri C, Cosenza C, Sanguigno L, Quinto I, Scala G, Netti PA
* Evolutionary screening and adsorption behavior of engineered M13 bacteriophage and derived dodecapeptide for selective decoration of gold interfaces (183 visite)
J Colloid Interface Sci (ISSN: 0021-9797, 1095-7103electronic, 0021-9797linking), 2013 Jan 1; 389(1): 220-229.
Impact Factor: 1.646
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Pannuzzo M, Milardi D, Raudino A, Karttunen M, La Rosa C
* Analytical model and multiscale simulations of Aβ peptide aggregation in lipid membranes: Towards a unifying description of conformational transitions, oligomerization and membrane damage (254 visite)
Phys Chem Chem Phys (ISSN: 1463-9076, 1463-3907, 1463-9084electronic), 2013; 15(23): 8940-8951.
Impact Factor: 4.198
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Attanasio F, De Bona P, Cataldo S, Sciacca MFM, Milardi D, Pignataro B, Pappalardo G
* Copper(II) and zinc(II) dependent effects on A beta 42 aggregation: a CD, Th-T and SFM study (238 visite)
New J Chem (ISSN: 1144-0546), 2013; 37(4): 1206-1215.
Impact Factor: 3.159
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Pannuzzo M, Raudino A, Milardi D, La Rosa C, Karttunen M
* α-Helical structures drive early stages of self-assembly of amyloidogenic amyloid polypeptide aggregate formation in membranes (221 visite)
Sci Rep (ISSN: 2045-2322, 2045-2322electronic, 2045-2322linking), 2013; 3: N/D-N/D.
Impact Factor: 5.078
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Roviello GN, Mottola A, Musumeci D, Bucci EM, Pedone C
* Synthesis and aggregation properties of a novel enzymatically resistant nucleoamino acid (220 visite)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2012 Oct; 43(4): 1465-1470.
Impact Factor: 3.914
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Stanzione F, De Simone A, Esposito L, Vitagliano L
* Dynamical Properties of Steric Zipper Polymorphs Formed by a IAPP-Derived Peptide (219 visite)
Protein Pept Lett (ISSN: 0929-8665, 1875-5305), 2012 Sep; 19(8): 846-851.
Impact Factor: 1.994
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Ascione G, de Pascale D, De Santi C, Pedone C, Dathan NA, Monti SM
* Native expression and purification of hormone-sensitive lipase from Psychrobacter sp. TA144 enhances protein stability and activity (271 visite)
Biochem Biophys Res Commun (ISSN: 1090-2104, 0006-291x, 1090-2104electronic), 2012 Apr 13; 420(3): 542-546.
Impact Factor: 2.406
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Musumeci D, Oliviero G, Roviello GN, Bucci EM, Piccialli G
* G-quadruplex-forming oligonucleotide conjugated to magnetic nanoparticles: Synthesis, characterization, and enzymatic stability assays (214 visite)
Bioconjug Chem (ISSN: 1043-1802, 1520-4812, 1520-4812electronic), 2012 Mar 21; 23(3): 382-391.
Impact Factor: 4.58
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Caraci F, Spampinato S, Sortino MA, Bosco P, Battaglia G, Bruno V, Drago F, Nicoletti F, Copani A
* Dysfunction of TGF-β1 signaling in Alzheimer's disease: Perspectives for neuroprotection (315 visite)
Cell Tissue Res (ISSN: 0302-766x), 2012 Jan; 347(1): 291-301.
Impact Factor: 3.677
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Arena G, Fattorusso R, Grasso G, Grasso GI, Isernia C, Malgieri G, Milardi D, Rizzarelli E
* Zinc(II) complexes of ubiquitin: speciation, affinity and binding features (277 visite)
Chemistry (ISSN: 1521-3765, 0947-6539, 1521-3765electronic), 2011 Oct 4; 17(41): 11596-11603.
Impact Factor: 5.925
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Raimondi S, Guglielmi F, Giorgetti S, Di Gaetano S, Arciello A, Monti DM, Relini A, Nichino D, Doglia SM, Natalello A, Pucci P, Mangione P, Obici L, Merlini G, Stoppini M, Robustelli P, Tartaglia GG, Vendruscolo M, Dobson CM, Piccoli R, Bellotti V
* Effects of the Known Pathogenic Mutations on the Aggregation Pathway of the Amyloidogenic Peptide of Apolipoprotein A-I (223 visite)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2011 Apr 1; 407(3): 465-476.
Impact Factor: 4.001
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Corona C, Frazzini V, Silvestri E, Lattanzio R, La Sorda R, Piantelli M, Canzoniero LM, Ciavardelli D, Rizzarelli E, Sensi SL
* Effects of dietary supplementation of carnosine on mitochondrial dysfunction, amyloid pathology, and cognitive deficits in 3xTg-AD mice (235 visite)
Plosone (ISSN: 1932-6203, 1932-6203electronic), 2011 Mar 15; 6(3): e17971-e17971.
Impact Factor: 4.092
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Accardo A, Morisco A, Gianolio E, Tesauro D, Mangiapia G, Radulescu A, Brandt A, Morelli G
* Nanoparticles containing octreotide peptides and gadolinium complexes for MRI applications (261 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2011 Feb; 17(2): 154-162.
Impact Factor: 1.799
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Milardi D, Sciacca MFM, Pappalardo M, Grasso DM, La Rosa C
* The Role Of Aromatic Side-Chains In Amyloid Growth And Membrane Interaction Of The Islet Amyloid Polypeptide Fragment Lanflvh (192 visite)
Eur Biophys J, 2011 Jan; 40(1): 1-12.
Impact Factor: 3.832
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Ruggiero A, Marasco D, Squeglia F, Soldini S, Pedone E, Pedone C, Berisio R
* Structure and functional regulation of RipA, a mycobacterial enzyme essential for daughter cell separation (163 visite)
Structure (ISSN: 0969-2126, 1878-4186), 2010 Sep 8; 18(9): 1184-1190.
Impact Factor: 6.337
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Castellano I, Merlino A, Rossi M, La Cara F
* Biochemical and structural properties of gamma-glutamyl transpeptidase from Geobacillus thermodenitrificans: An enzyme specialized in hydrolase activity (243 visite)
Biochimie (ISSN: 0300-9084, 1638-6183, 1638-6183electronic), 2010 May; 92(5): 464-474.
Impact Factor: 3.787
Dettagli Esporta in BibTeX Esporta in EndNote
Roviello GN, Di Gaetano S, Capasso D, Cesarani A, Bucci EM, Pedone C
* Synthesis, spectroscopic studies and biological activity of a novel nucleopeptide with Moloney murine leukemia virus reverse transcriptase inhibitory activity (187 visite)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010 May; 38(5): 1489-1496.
Impact Factor: 4.106
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Canettieri G, Di Marcotullio L, Greco A, Coni S, Antonucci L, Infante P, Pietrosanti L, De Smaele E, Ferretti E, Miele E, Pelloni M, De Simone G, Pedone E, Gallinari P, Giorgi A, Steinkuhler C, Vitagliano L, Pedone C, Schinin ME, Screpanti I, Gulino A
* Histone deacetylase and Cullin3-REN(KCTD11) ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation (252 visite)
Nature Cell Biol Nature Cell Biology (ISSN: 1476-4679, 1465-7392), 2010 Feb; 12(2): 132-142.
Impact Factor: 19.407
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Severino V, Chambery A, Vitiello M, Cantisani M, Galdiero S, Galdiero M, Malorni L, Di Maro A, Parente A
* Proteomic Analysis of Human U937 Cell Line Activation Mediated by Haemophilus influenzae Type b P2 Porin and Its Surface-Exposed Loop (151 visite)
J Proteome Res (ISSN: 1535-3893), 2010 Feb; 9(2): 1050-1062.
Impact Factor: 5.46
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Mazzaglia A, Micali N, Scolaro LM, Attanasio F, Magrí A, Pappalardo G, Villari V
* Aggregation properties of the peptide fragments derived from the 17-29 region of the human and rat IAPP: A comparative study with two PEG-conjugated variants of the human sequence (264 visite)
J Phys Chem B (ISSN: 1520-6106, 1520-5207, 1520-5207electronic), 2010 Jan 21; 114(2): 705-713.
Impact Factor: 3.603
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D'Urso L, Grasso G, Messina E, Bongiorno C, Scuderi V, Scalese S, Puglisi O, Spoto G, Compagnini G
* The Role of Linear Carbon Chains in the Aggregation of Copper, Silver, and Gold Nanoparticles (238 visite)
J Phys Chem C (ISSN: 1932-7447), 2010 Jan 21; 114(2): 907-915.
Impact Factor: 4.524
Dettagli Esporta in BibTeX Esporta in EndNote
Satriano C, Messina GM, Marino C, Aiello I, Conte E, La Mendola D, Distefano DA, D'Alessandro F, Pappalardo G, Impellizzeri G
* Surface immobilization of fibronectin-derived PHSRN peptide on functionalized polymer films - Effects on fibroblast spreading (270 visite)
J Colloid Interface Sci (ISSN: 1095-7103electronic, 0021-9797linking), 2010 Jan 15; 341(2): 232-239.
Impact Factor: 3.068
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Roviello GN, Musumeci D, De Cristofaro A, Capasso D, Di Gaetano S, Bucci EM, Pedone C
* Alternate dab-aegPNAs: synthesis, nucleic acid binding studies and biological activity (208 visite)
Mol Biosyst (ISSN: 1742-2051, 1742-206x, 1742-2051electronic), 2010 Jan; 6(1): 199-205.
Impact Factor: 3.825
Dettagli Esporta in BibTeX Esporta in EndNote
Palmieri G, Langella E, Gogliettino M, Saviano M, Pocsfalvi G, Rossi M
* A novel class of protease targets of phosphatidylethanolamine-binding proteins (PEBP): A study of the acylpeptide hydrolase and the PEBP inhibitor from the archaeon Sulfolobus solfataricus (136 visite)
Mol Biosyst (ISSN: 1742-206x), 2010; 6(12): 2498-2507.
Impact Factor: 3.825
Dettagli Esporta in BibTeX Esporta in EndNote
Giuffrida ML, Caraci F, De Bona P, Pappalardo G, Nicoletti F, Rizzarelli E, Copani A
* The monomer state of beta-amyloid: where the Alzheimer's disease protein meets physiology (230 visite)
Rev Neurosci (ISSN: 0334-1763), 2010; 21(2): 83-93.
Impact Factor: 2.047
Dettagli Esporta in BibTeX Esporta in EndNote
Cigliano L, Pugliese CR, Spagnuolo MS, Palumbo R, Abrescia P
* Haptoglobin binds the antiatherogenic protein apolipoprotein e - Impairment of apolipoprotein e stimulation of both lecithin: Cholesterol acyltransferase activity and cholesterol uptake by hepatocytes (175 visite)
Febs J (ISSN: 1742-464x), 2009 Nov; 276(21): 6158-6171.
Impact Factor: 3.042
Dettagli Esporta in BibTeX Esporta in EndNote
Arnesano F, Scintilla S, Calò V, Bonfrate E, Ingrosso C, Losacco M, Pellegrino T, Rizzarelli E, Natile G
* Copper-triggered aggregation of ubiquitin (244 visite)
Plosone (ISSN: 1932-6203, 1932-6203electronic), 2009 Sep 16; 4(9): e7052-e7052.
Impact Factor: 4.351
Dettagli Esporta in BibTeX Esporta in EndNote
Accardo A, Tesauro D, Morisco A, Mangiapia G, Vaccaro M, Gianolio E, Heenan RK, Paduano L, Morelli G
* Micelles obtained by aggregation of gemini surfactants containing the CCK8 peptide and a gadolinium complex (221 visite)
J Biol Inorg Chem (ISSN: 0949-8257, 1432-1327electronic, 0949-8257linking), 2009 May; 14(4): 587-599.
Impact Factor: 3.415
Dettagli Esporta in BibTeX Esporta in EndNote
De Bona P, Giuffrida ML, Caraci F, Copani A, Pignataro B, Attanasio F, Cataldo S, Pappalardo G, Rizzarelli E
* Design And Synthesis Of New Trehalose-Conjugated Pentapeptides As Inhibitors Of Abeta (1-42) Fibrillogenesis And Toxicity (317 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 220-228.
Impact Factor: 1.807
Dettagli Esporta in BibTeX Esporta in EndNote
D'Auria G, Vacatello M, Falcigno L, Paduano L, Mangiapia G, Calvanese L, Gambaretto R, Dettin M, Paolillo L
* Self-assembling properties of ionic-complementary peptides (224 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 210-219.
Impact Factor: 1.807
Dettagli Esporta in BibTeX Esporta in EndNote
Ruggiero A, Tizzano B, Pedone E, Pedone C, Wilmanns M, Berisio R
* Crystal Structure of the Resuscitation-Promoting Factor (Delta DUF)RpfB from M. tuberculosis (173 visite)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2009 Jan 9; 385(1): 153-162.
Impact Factor: 3.871
Dettagli Esporta in BibTeX Esporta in EndNote
Vaccaro M, Mangiapia G, Radulescu A, Schillen K, D'Errico G, Morelli G, Paduano L
* Colloidal particles composed of amphiphilic molecules binding gadolinium complexes and peptides as tumor-specific contrast agents in MRI: physico-chemical characterization (303 visite)
Soft Matter (ISSN: 1744-683x), 2009; 5(13): 2504-2512.
Impact Factor: 4.869
Dettagli Esporta in BibTeX Esporta in EndNote
Vitagliano L, Esposito L, Pedone C, De Simone A
* Stability of single sheet GNNQQNY aggregates analyzed by replica exchange molecular dynamics: antiparallel versus parallel association (251 visite)
Biochem Biophys Res Commun (ISSN: 1090-2104, 0006-291x, 1090-2104electronic), 2008 Dec 26; 377(4): 1036-1041.
Impact Factor: 2.648
Dettagli Esporta in BibTeX Esporta in EndNote
Milardi D, Pappalardo M, Pannuzzo M, Grasso DM, Rosa CL
* The role of the Cys2-Cys7 disulfide bridge in the early steps of Islet amyloid polypeptide aggregation: A molecular dynamics study (249 visite)
Chem Phys Lett (ISSN: 0009-2614), 2008 Oct 1; 463(4-6): 396-399.
Impact Factor: 2.169
Dettagli Esporta in BibTeX Esporta in EndNote
Marasco D, Perretta G, Sabatella M, Ruvo M
* Past and Future Perspectives of Synthetic Peptide Libraries (190 visite)
Curr Protein Pept Sci (ISSN: 1389-2037), 2008 Oct; 9(5): 447-467.
Impact Factor: 3.011
Dettagli Esporta in BibTeX Esporta in EndNote
Galdiero S, Vitiello M, Falanga A, D'Isanto M, Cantisani M, Kampanaraki A, Benedetti E, Browne H, Galdiero M
* Peptides containing membrane-interacting motifs inhibit herpes simplex virus type 1 infectivity (234 visite)
Peptides (ISSN: 0196-9781, 1873-5169electronic, 0196-9781linking), 2008 Sep; 29(9): 1461-1471.
Impact Factor: 2.565
Dettagli Esporta in BibTeX Esporta in EndNote
Grimaldi P, Ruocco MR, Lanzotti MA, Ruggiero A, Ruggiero I, Arcari P, Vitagliano L, Masullo M
* Characterisation of the components of the thioredoxin system in the archaeon Sulfolobus solfataricus (167 visite)
Extremophiles (ISSN: 1431-0651, 1433-4909, 1433-4909electronic), 2008 Jul; 12(4): 553-562.
Impact Factor: 1.782
Dettagli Esporta in BibTeX Esporta in EndNote
Tornatore L, Marasco D, Dathan N, Vitale RM, Benedetti E, Papa S, Franzoso G, Ruvo M, Monti SM
* Gadd45 beta forms a homodimeric complex that binds tightly to MKK7 (237 visite)
J Mol Biol (ISSN: 0022-2836, 0022-2283, 1089-8638), 2008 Apr 18; 378(1): 97-111.
Impact Factor: 5.673
Dettagli Esporta in BibTeX Esporta in EndNote
Cigliano L, Maresca B, Salvatore A, Nino M, Monfrecola G, Ayala F, Carlucci A, Pugliese RC, Pedone C, Abrescia P
* Haptoglobin from psoriatic patients exhibits decreased activity in binding haemoglobin and inhibiting lecithin-cholesterol acyltransferase activity (156 visite)
Journal Of The European Academy Of Dermatology And Venereology (ISSN: 1468-3083, 0926-9959), 2008 Apr; 22(4): 417-425.
Impact Factor: 2.276
Dettagli Esporta in BibTeX Esporta in EndNote
De Simone A, Pedone C, Vitagliano L
* Structure, dynamics, and stability of assemblies of the human prion fragment SNQNNF (236 visite)
Biochem Biophys Res Commun (ISSN: 1090-2104, 0006-291x, 1090-2104electronic), 2008 Feb 15; 366(3): 800-806.
Impact Factor: 2.648
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Randazzo R, Mammana A, D'Urso A, Lauceri R, Purrello R
* Reversible "chiral memory" in ruthenium tris(phenanthroline)- anionic porphyrin complexes (201 visite)
Angew Chem Int Ed (ISSN: 1433-7851, 1521-3773electronic, 1433-7851linking), 2008; 47(51): 9879-9882.
Impact Factor: 10.879
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Gomez-monterrey Isabel M, Campiglia P, Bertamino A, Aquino C, Mazzoni O, Diurno Maria V, Iacovino R, Saviano M, Sala M, Novellino E, Grieco P
* Synthesis of Novel Indole-Based Ring Systems by Acid-Catalysed Condensation from α-Amino Aldehydes and L-Trp-OMe (116 visite)
Eur J Org Chem (ISSN: 1099-0690), 2008; 2008(11): 1983-1992.
Impact Factor: 0
Dettagli Esporta in BibTeX Esporta in EndNote
Gomez-monterrey IM, Campiglia P, Bertamino A, Aquino C, Mazzoni O, Diurno MV, Iacovino R, Saviano M, Sala M, Novellino E, Grieco P
* Synthesis Of Novel Indole-Based Ring Systems By Acid-Catalyzed Condensation From A-Amino Aldehydes And L-Trp-Ome (149 visite)
European Journal Of Organic Chemistry (ISSN: 1434-193x), 2008; 11: 1983-1992.
Impact Factor: 3.016
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Grasso G, Rizzarelli E, Spoto G
* AP/MALDI-MS complete characterization of the proteolytic fragments produced by the interaction of insulin degrading enzyme with bovine insulin (227 visite)
J Mass Spectrom (ISSN: 1076-5174, 1096-9888), 2007 Dec; 42(12): 1590-1598.
Impact Factor: 3.062
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Salvatore A, Cigliano L, Bucci EM, Corpillo D, Velasco S, Carlucci A, Pedone C, Abrescia P
* Haptoglobin binding to apolipoprotein A-I prevents damage from hydroxyl radicals on its stimulatory activity of the enzyme lecithin-cholesterol acyl-transferase (176 visite)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2007 Oct 2; 46(39): 11158-11168.
Impact Factor: 3.368
Dettagli Esporta in BibTeX Esporta in EndNote
Vaccaro M, Accardo A, D'Errico G, Schillen K, Radulescu A, Tesauro D, Morelli G, Paduano L
* Peptides and gd complexes containing colloidal assemblies as tumor-specific contrast agents in MRI: Physicochemical characterization (192 visite)
Biophysical Journal (ISSN: 0006-3495, 1542-0086), 2007 Sep; 93(5): 1736-1746.
Impact Factor: 4.627
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Tesauro D, Accardo A, Gianolio E, Paduano L, Teixeira J, Schillén K, Aime S, Morelli G
* Peptide derivatized lamellar aggregates as target-specific MRI contrast agents (217 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2007 May 25; 8(8): 950-955.
Impact Factor: 3.446
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Attanasio F, Cascio C, Fisichella S, Nicoletti VG, Pignataro B, Savarino A, Rizzarelli E
* Trehalose effects on alpha-crystallin aggregates (235 visite)
Biochem Biophys Res Commun (ISSN: 0006-291x, 0006-291xlinking), 2007 Mar 23; 354(4): 899-905.
Impact Factor: 2.749
Dettagli Esporta in BibTeX Esporta in EndNote
Giuffrida ML, Grasso G, Ruvo M, Pedone C, Saporito A, Marasco D, Pignataro B, Cascio C, Copani A, Rizzarelli E
* Abeta(25-35) And Its C- And/Or N-Blocked Derivatives: Copper Driven Structural Features And Neurotoxicity (260 visite)
Journal Of Neuroscience Research (ISSN: 0360-4012), 2007 Feb 15; 85(3): 623-633.
Impact Factor: 3.268
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Accardo A, Tesauro D, Morelli G, Gianolio E, Aime S, Vaccaro M, Mangiapia G, Paduano L, Schillén K
* High-relaxivity supramolecular aggregates containing peptides and Gd complexes as contrast agents in MRI (212 visite)
J Biol Inorg Chem (ISSN: 0949-8257, 1432-1327electronic, 0949-8257print), 2007 Feb; 12(2): 267-276.
Impact Factor: 3.325
Dettagli Esporta in BibTeX Esporta in EndNote
Arena G, Deretzis I, Forte G, Giannazzo F, La Magna A, Lombardo G, Raineri V, Sgarlata C, Spoto G
* Electron transport properties of calix[4]arene based systems in a metal-molecule-metal junction (168 visite)
New J Chem (ISSN: 1144-0546), 2007; 31(5): 756-761.
Impact Factor: 2.651
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Cucinotta V, Giuffrida A, Grasso G, Maccarrone G, Messina M, Vecchio G
* High selectivity in new chiral separations of dansyl amino acids by cyclodextrin derivatives in electrokinetic chromatography (160 visite)
J Chromatogr A (ISSN: 0021-9673), 2007; 1155(2): 172-179.
Impact Factor: 3.641
Dettagli Esporta in BibTeX Esporta in EndNote
Esposito L, Pedone C, Vitagliano L
* Molecular dynamics analyses of cross-beta-spine steric zipper models: beta-sheet twisting and aggregation (264 visite)
P Natl Acad Sci Usa (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2006 Sep 1; 103(31): 11533-11538.
Impact Factor: 9.643
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Merlino A, Esposito L, Vitagliano L
* Polyglutamine Repeats And Beta-Helix Structure: Molecular Dynamics Study (260 visite)
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2006 Jun 1; 63(4): 918-927.
Impact Factor: 3.73
Dettagli Esporta in BibTeX Esporta in EndNote
Galdiero S, Vitiello M, D'Isanto M, Falanga A, Collins C, Raieta K, Pedone C, Browne H, Galdiero M
* Analysis of synthetic peptides from heptad-repeat domains of herpes simplex virus type 1 glycoproteins H and (226 visite)
Journal Of General Virology (ISSN: 0022-1317), 2006 May; 87: 1085-1097.
Impact Factor: 3.11
Dettagli Esporta in BibTeX Esporta in EndNote
Mannini R, Rivieccio V, D'Auria S, Tanfani F, Ausili A, Pedone C, Grimaldi G, Facchiano A
* Structure/function of KRAB repression domains: Structural properties of KRAB modules inferred from hydrodynamic, circular dichroism, and FTIR spectroscopic analyses (235 visite)
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2006 Feb 15; 62(3): 604-616.
Impact Factor: 3.73
Dettagli Esporta in BibTeX Esporta in EndNote
Cucinotta V, Giuffrida A, Maccarrone G, Messina M, Puglisi A, Rizzarelli E, Vecchio G
* Coordination properties of 3-functionalized β-cyclodextrins. Thermodynamic stereoselectivity of copper(II) complexes of the A, B-diamino derivative and its exploitation in LECE (177 visite)
Dalton T (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2005 Sep 21; (16): 2731-2736.
Impact Factor: 3.003
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Angela M, Massimo De N, Rosaria L, Roberto P
* Induction and memory of chirality in porphyrin hetero-aggregates: The role of the central metal ion (212 visite)
Bioorg Med Chem (ISSN: 0968-0896, 1464-3391, 1464-3391electronic), 2005 Sep 1; 13(17): 5159-5163.
Impact Factor: 2.286
Dettagli Esporta in BibTeX Esporta in EndNote
Bucci E, Vitagliano L, Barone R, Sorrentino S, D'Alessio G, Graziano G
* On the thermal stability of the two dimeric forms of ribonuclease (176 visite)
Biophys Chem (ISSN: 0301-4622, 0301-4622linking), 2005 Jul 1; 116(2): 89-95.
Impact Factor: 1.925
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Naddeo M, Vitagliano L, Russo A, Gotte G, D'Alessio G, Sorrentino S
* Interactions of the cytotoxic RNase A dimers with the cytosolic ribonuclease inhibitor (130 visite)
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 2005 May 9; 579(12): 2663-2668.
Impact Factor: 3.415
Dettagli Esporta in BibTeX Esporta in EndNote
Tizzano B, Palladino P, De Capua A, Marasco D, Rossi F, Benedetti E, Pedone C, Ragone R, Ruvo M
* The Human Prion Protein Alpha2 Helix: A Thermodynamic Study Of Its Conformational Preferences (202 visite)
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2005 Apr 1; 59(1): 72-79.
Impact Factor: 4.684
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La Rosa C, Milardi D, Amato E, Pappalardo M, Grasso D
* Molecular mechanism of the inhibition of cytochrome c aggregation by Phe-Gly (254 visite)
Arch Biochem Biophys (ISSN: 0003-9861), 2005 Mar 1; 435(1): 182-189.
Impact Factor: 3.152
Dettagli Esporta in BibTeX Esporta in EndNote
Merlino A, Ceruso MA, Vitagliano L, Mazzarella L
* Open interface and large quaternary structure movements in 3D domain swapped proteins: Insights from molecular dynamics simulations of the C-terminal swapped dimer of ribonuclease (243 visite)
Biophysical Journal (ISSN: 0006-3495, 1542-0086), 2005 Mar; 88(3): 2003-2012.
Impact Factor: 4.507
Dettagli Esporta in BibTeX Esporta in EndNote
Spagnuolo MS, Cigliano L, D'Andrea LD, Pedone C, Abrescia P
* Assignment of the binding site for haptoglobin on apolipoprotein A-I (182 visite)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2005 Jan 14; 280(2): 1193-1198.
Impact Factor: 5.854
Dettagli Esporta in BibTeX Esporta in EndNote
Rivieccio V, Mannini R, Concilio L, D'Auria S, Pedone C, Grimaldi G
* Expression, purification and partial characterization of the Krüppel-associated box (KRAB) from the human ZNF2 protein (136 visite)
Protein Pept Lett (ISSN: 0929-8665, 1875-5305), 2005; 12(6): 527-532.
Impact Factor: 0.84
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Mischiati C, Sereni A, Finotti A, Breda L, Cortesi R, Nastruzzi C, Romanelli A, Saviano M, Bianchi N, Pedone C, Borgatti M, Gambari R
* Complexation to cationic microspheres of double-stranded peptide nucleic acid-DNA chimeras exhibiting decoy activity (143 visite)
Journal Of Biomedical Science (ISSN: 1021-7770), 2004 Sep; 11(5): 697-704.
Impact Factor: 1.567
Dettagli Esporta in BibTeX Esporta in EndNote
Cucinotta V, Giuffrida A, La Mendola D, Maccarrone G, Puglisi A, Rizzarelli E, Vecchio G
* 3-Amino Derivative Of Beta-Cyclodextrin: Thermodynamics Of Copper (ii) Complexes And Exploitation Of Its Enantioselectivity In The Separation Of Amino Acid Racemates By Ligand Exchange Capillary Electrophoresis (175 visite)
And Life Sciencesjournal Of Chromatography B Analytical Technologies In The Biomedical, 2004 Feb 5; 800(1-2): 127-133.
Impact Factor: 1.403
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Pedone E, Bartolucci S, Rossi M, Pierfederici FM, Scire A, Cacciamani T, Tanfani F
* Structural and thermal stability analysis of Escherichia coli and Alicyclobacillus acidocaldarius thioredoxin revealed a molten globule-like state in thermal denaturation pathway of the proteins: an infrared spectroscopic study (236 visite)
Biochem J (ISSN: 0264-6021, 1470-8728electronic, 0264-6021linking), 2003 Sep 1; 373: 875-883.
Impact Factor: 4.101
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D'Ambrosio K, Kauffmann B, Rouhier N, Benedetti E, Jacquot JP, Aubry A, Corbier C
* Crystallization and preliminary X-ray studies of the glutaredoxin from poplar in complex with glutathione (115 visite)
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2003 Jun; 59: 1043-1045.
Impact Factor: 2.208
Dettagli Esporta in BibTeX Esporta in EndNote
Grasso D, Milardi D, Guantieri V, La Rosa C, Rizzarelli E
* Interaction of prion peptide PrP 180-193 with DPPC model membranes: A thermodynamic study (215 visite)
New J Chem (ISSN: 1144-0546), 2003; 27(2): 359-364.
Impact Factor: 2.272
Dettagli Esporta in BibTeX Esporta in EndNote
Cucinotta V, Giuffrida A, Grasso G, Maccarrone G, Vecchio G
* Ligand exchange chiral separations by cyclodextrin derivatives in capillary electrophoresis (138 visite)
Analyst (ISSN: 0003-2654), 2003; 128(2): 134-136.
Impact Factor: 2.251
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Cucinotta V, Giuffrida A, Grasso G, Maccarrone G, Messina M
* The Simultaneous Separation Of Different Enantiomeric Pairs In Capillary Electrophoresis By Mixing Different Hemispherodextrins, A Very Versatile Class Of Receptors (160 visite)
J Chromatogr A (ISSN: 0021-9673), 2002 Dec 6; 979(1-2): 137-145.
Impact Factor: 3.098
Dettagli Esporta in BibTeX Esporta in EndNote
Esposito G, Vitagliano L, Santamaria R, Viola A, Zagari A, Salvatore F
* Structural and functional analysis of aldolase B mutants related to hereditary fructose intolerance (147 visite)
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 2002 Nov 6; 531(2): 152-156.
Impact Factor: 3.912
Dettagli Esporta in BibTeX Esporta in EndNote
Orru S, Ruoppolo M, Francese S, Vitagliano L, Marino G, Esposito C
* Identification of tissue transglutaminase-reactive lysine residues in glyceraldehyde-3-phosphate dehydrogenase (9528 visite)
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic), 2002 Jan; 11(1): 137-146.
Impact Factor: 3.546
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Cambria M, Cambria A, Ragusa S, Rizzarelli E
Production, purification, and properties of an extracellular laccase from Rigidoporus lignosus (145 visite)
Protein Expr Purif (ISSN: 1046-5928), 2000 Mar; 18(2): 141-147.
Impact Factor: 1.569
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Fonti R, Latella G, Caprilli R, Frieri G, Marcheggiano A, Sambuy Y
Carbonic anhydrase I reduction in colonic mucosa of patients with active ulcerative colitis (115 visite)
Digestive Diseases And Sciences (ISSN: 0163-2116), 1998; 43(9): 2086-2092.
Impact Factor: 1.972
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Adinolfi S, Piccoli R, Sica F, Mazzarella L
BS-RNase tetramers: An example of domain-swapped oligomers (160 visite)
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 1996 Dec 2; 398(2-3): 326-332.
Impact Factor: 3.504
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FRITTITTA L, VIGNERI R, PAPA V, GOLDFINE I, GRASSO G, TRISCHITTA V
Structural and functional studies of insulin receptors in human breast cancer (134 visite)
Breast Cancer Res Tr Kluwer Academic Publishers (ISSN: 0167-6806), 1993; 25(1): 73-82.
Impact Factor: 2.43
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Della Ragione F, Oliva A, Palumbo R, Russo GL, Gragnaniello V, Zappia V
Deficiency of 5'-deoxy-5'-methylthioadenosine phosphorylase activity in malignancy. Absence of the protein in human enzyme-deficient cell lines (117 visite)
Biochem J (ISSN: 0264-6021print, 0264-6021linking, 1470-8728electronic), 1992 Jan 15; 281(Pt2): 533-538.
Impact Factor: 3.579
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Montanaro V, Casamassimi A, D'Urso M, Yoon JY, Freije W, Schlessinger D, Muenke M, Nussbaum RL, Saccone S, Maugeri S
In Situ Hybridization To Cytogenetic Bands Of Yeast Artificial Chromosomes Covering 50% Of Human Xq24-Xq28 Dna (80 visite)
Am J Hum Genet, 1991 Feb; 48(2): 183-194.
Impact Factor: 0
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Gurrieri S, Rizzarelli E, Beach D, Bustamante C
Imaging of kinked configurations of DNA molecules undergoing orthogonal field alternating gel electrophoresis by fluorescence microscopy (122 visite)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 1990 Apr 3; 29(13): 3396-3401.
Impact Factor: 4.572
Dettagli Esporta in BibTeX Esporta in EndNote
137 Records (132 escludendo Abstract e Conferenze).
Impact factor totale: 510.14 (487.271 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 517.638 (498.907 escludendo Abstract e Conferenze).
Impact factor totale: 510.14 (487.271 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 517.638 (498.907 escludendo Abstract e Conferenze).
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