Nanostructures based on monoolein or diolein and amphiphilic gadolinium complexes as MRI contrast agents
CNR Ibb | back to homepage
▲NavBar
Ricerca avanzata▼
Contiene: [X]      Estesa     Autori: [X]  Tipo di lavoro: [X]   Data iniziale: Data finale: [X]      Sede: Affiliazione IBB     
    
[Pulisci modulo]


Nanostructures based on monoolein or diolein and amphiphilic gadolinium complexes as MRI contrast agents (195 visite)

Accardo A, Gianolio E, Arena F, Barnert S, Schubert R, Tesauro D, Morelli G

J Mater Chem B (ISSN: 2050-7518, 2050-750x), 2013; 1(5): 617-628.



Tipo di articolo: Journal Article,

Impact factor: 8.535, Impact factor a 5 anni: 8.419

Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84876529807&partnerID=40&md5=940d1a0b5a9a34825d4386fa3e3fd078

Parole chiave: Delivery Systems, Folate Receptor, Gadolinium Complexes, Low Concentrations, Mri Contrast Agents, Relaxometric Properties, Short Incubations, Structural Behaviors, Doping (additives), Gadolinium Compounds, Monomers, Organic Acids, Nanostructures,

Affiliazioni:

*** IBB - CNR ***
CIRPeB, Department of Pharmacy, University of Naples Federico II, Via Mezzocannone, 16, 80134 Napoli, Italy
Department of Chemistry I.F.M., Molecular Imaging Centre, University of Turin, Via Nizza, 52, 10125 Turin, Italy


Riferimenti:

Young, I.R., (2000) Methods in Biomedical Magnetic Resonance Imaging and Spectroscopy, , John Wiley & Sons Ltd., Chicheste

Rinck, P.A., (2003) Magnetic Resonance in Medicine, , ABW Wissenschaftsverlag GmbH, Berlin

Li, J., Zheng, D., Bae, K.T., Woodard, P.K., Haacke, E.M., (1998) Invest. Radiol., 33, pp. 578-586

Mühler, A., (1998) Invest. Radiol., 33, pp. 709-714

Mühler, A., (1995) MAGMA, 3, pp. 21-33

Delli Castelli, D., Gianolio, E., Geninatti Crich, S., Terreno, E., Aime, S., (2008) Coord. Chem. Rev., 252, pp. 2424-2443

Mulder, W.J.M., Strijkers, G.J., Van Tilborg, G.A.F., Cormode, D.P., Fayad, Z.A., Nicolay, K., (2009) Acc. Chem. Res., 42, pp. 904-914

Accardo, A., Tesauro, D., Aloj, L., Pedone, C., Morelli, G., (2009) Coord. Chem. Rev., 253 (1718), pp. 2193-2213

Tesauro, D., Accardo, A., Gianolio, E., Paduano, L., Texeira, J., Schillen, K., Aime, S., Morelli, G., (2007) ChemBioChem, 8, pp. 950-955

Mulder, W.J.M., Van Der Schaft, D.W.J., Hautvast, P.A.I., Strijkers, G.J., Koning, G.A., Storm, G., Mayo, K.H., Nicolay, K., (2007) FASEB J, 21 (2), pp. 378-383

Brandwijk, R.J.M.G.E., Mulder, W.J.M., Nicolay, K., Mayo, K.H., Thijssen, V.L.J.L., Griffioen, A.W., (2007) Bioconjugate Chem., 18, pp. 785-790

Vaccaro, M., Mangiapia, G., Paduano, L., Gianolio, E., Accardo, A., Tesauro, D., Morelli, G., (2007) ChemPhysChem, 8, pp. 2526-2538

Lipinski, M.J., Amirbekian, V., Frias, J.C., Aguinado, J.G.S., Mani, V., Briley-Saebo, K.C., Fuster, V., Fayad, Z.A., (2006) Magn. Reson. Med., 56 (3), pp. 601-610

Amirbekian, V., Lipinski, M.J., Briley-Saebo, K.C., Amirbekian, S., Aguinado, J.G.S., Weinreb, D.B., Vucic, E., Fayad, Z.A., (2007) Proc. Natl. Acad. Sci. U. S. A., 104 (3), pp. 961-966

Yaghmur, A., Glatter, O., (2009) Adv. Colloid Interface Sci., 147-148, pp. 333-342

Liu, G., Conn, C.E., Waddington, L.J., Mudie, S.T., Drummond, C.J., (2010) Langmuir, 26 (4), pp. 2383-2391

Conn, C.E., Panchagnula, V., Weerawardena, A., Waddington, L.J., Kennedy, D.F., Drummond, C.J., (2010) Langmuir, 26 (9), pp. 6240-6249

Moghaddam, M.J., De Campo, L., Waddington, L.J., Weerawardena, A., Kirby, N., Drummond, C.J., (2011) Soft Matter, 7, pp. 10994-11005

Accardo, A., Morisco, A., Gianolio, E., Tesauro, D., Mangiapia, G., Radulescu, A., Brandte, A., Morelli, G., (2011) J. Pept. Sci., 17, pp. 154-162

Schmitt, L., Dietrich, C., Tampe, R., (1994) J. Am. Chem. Soc., 116, pp. 8485-8491

Sharma, S.K., Lown, J.W., (2002) Tetrahedron Lett., 43, pp. 6665-6667

Dubochet, J., Adrian, M., Chang, J.J., Homo, J.C., Lepault, J., McDowall, A.W., Schultz, P., (1988) Q. Rev. Biophys., 21, pp. 129-228

Talmon, Y., (1996) Ber. Bunsenges. Phys. Chem., 100, pp. 364-372

Rank, A., Hauschild, S., Förster, S., Schubert, R., (2009) Langmuir, 25, pp. 1337-1344

Arena, F., Jebasingh, B.S., Gianolio, E., Stefania, R., Aime, S., (2011) Bioconjugate Chem., 22, pp. 2625-2635

Bradford, M.M., (1976) Anal. Biochem., 72, pp. 248-254

Gustafsson, J., Ljusberg-Wahren, H., Almgren, M., Larsson, K., (1997) Langmuir, 13, pp. 6964-6971

Spicer, P.T., Hayden, K.L., Lynch, M.L., Ofori-Boateng, A., Burns, J.L., (2001) Langmuir, 17 (13), pp. 5748-5756

Solomon, I., (1955) Phys. Rev., 99, pp. 559-565

Bloembergen, N., (1957) J. Chem. Phys., 27, pp. 572-573

Bloembergen, N., Morgan, L.O., (1961) J. Chem. Phys., 34, pp. 842-850

Aime, S., Botta, M., Fasano, M., Terreno, E., (2001) The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging, p. 5. , ed. A. E. Merbach and E. Toth, John Wiley & Sons LTD

Bertini, I., Luchinat, C., (1996) Coord. Chem. Rev., 50, pp. 1-300

Kamaly, N., Kalber, T., Thanaou, M., Bell, D.J., Miller, A.D., (2009) Bioconjugate Chem., 20, pp. 648-655

Mangiapia, G., Vaccaro, M., D'Errico, G., Frielinghaus, H., Radulescu, A., Pipich, V., Carnerup, A.M., Paduano, L., (2011) Soft Matter, 7, pp. 10577-10580

Hilgenbrik, A.R., Low, P.S., (2005) J. Pharm. Sci., 94, pp. 2135-2142

Sega, E.I., Low, P.S., (2008) Cancer Metastasis Rev., 27, pp. 655-664

Kim, I.B., Shin, H., Garcia, A.L., Bunz, U.H.F., (2007) Bioconjugate Chem., 18, pp. 815-820

Choi, H., Choi, S.R., Zhou, R., Kung, H.F., Chen, I.W., (2004) Acad. Radiol., 11, pp. 996-1004

Ding, N., Lu, Y., Lee, R., Yang, C., Huang, L., Liu, J., Xiang, G., (2011) Int. J. Nanomed., 6, pp. 2513-2520

Low, P.S., Henne, W.A., Doorneweerd, D.D., (2008) Acc. Chem. Res., 41, pp. 120-129

Barauskas, J., Cervin, C., Jankunenc, M., Spandyreva, M., Ribokaite, K., Tiberg, F., Johnsson, M., (2010) Int. J. Pharm., 391, pp. 284-291

Murgia, S., Falchi, A.M., Mano, M., Lampis, S., Angius, R., Carnerup, A.M., Schmidt, J., Monduzzi, M., (2010) J. Phys. Chem. B, 114, pp. 3518-3525

Sahay, G., Batrakova, E.V., Kabanov, A.V., (2008) Bioconjugate Chem., 19, pp. 2023-2029

Li, X., Chen, D., Le, C., Zhu, C., Gang, Y., Hovgaard, L., Yang, M., (2011) Int. J. Nanomed., 6, pp. 3151-3162

Young, I. R., (2000) Methods in Biomedical Magnetic Resonance Imaging and Spectroscopy, , John Wiley & Sons Ltd., Chicheste

Rinck, P. A., (2003) Magnetic Resonance in Medicine, , ABW Wissenschaftsverlag GmbH, Berlin

M hler, A., (1998) Invest. Radiol., 33, pp. 709-714

M hler, A., (1995) MAGMA, 3, pp. 21-33

Mulder, W. J. M., Strijkers, G. J., Van Tilborg, G. A. F., Cormode, D. P., Fayad, Z. A., Nicolay, K., (2009) Acc. Chem. Res., 42, pp. 904-914

Mulder, W. J. M., Van Der Schaft, D. W. J., Hautvast, P. A. I., Strijkers, G. J., Koning, G. A., Storm, G., Mayo, K. H., Nicolay, K., (2007) FASEB J, 21 (2), pp. 378-383

Brandwijk, R. J. M. G. E., Mulder, W. J. M., Nicolay, K., Mayo, K. H., Thijssen, V. L. J. L., Griffioen, A. W., (2007) Bioconjugate Chem., 18, pp. 785-790

Lipinski, M. J., Amirbekian, V., Frias, J. C., Aguinado, J. G. S., Mani, V., Briley-Saebo, K. C., Fuster, V., Fayad, Z. A., (2006) Magn. Reson. Med., 56 (3), pp. 601-610

Liu, G., Conn, C. E., Waddington, L. J., Mudie, S. T., Drummond, C. J., (2010) Langmuir, 26 (4), pp. 2383-2391

Conn, C. E., Panchagnula, V., Weerawardena, A., Waddington, L. J., Kennedy, D. F., Drummond, C. J., (2010) Langmuir, 26 (9), pp. 6240-6249

Moghaddam, M. J., De Campo, L., Waddington, L. J., Weerawardena, A., Kirby, N., Drummond, C. J., (2011) Soft Matter, 7, pp. 10994-11005

Sharma, S. K., Lown, J. W., (2002) Tetrahedron Lett., 43, pp. 6665-6667

Bradford, M. M., (1976) Anal. Biochem., 72, pp. 248-254

Spicer, P. T., Hayden, K. L., Lynch, M. L., Ofori-Boateng, A., Burns, J. L., (2001) Langmuir, 17 (13), pp. 5748-5756

Hilgenbrik, A. R., Low, P. S., (2005) J. Pharm. Sci., 94, pp. 2135-2142

Sega, E. I., Low, P. S., (2008) Cancer Metastasis Rev., 27, pp. 655-664

Kim, I. B., Shin, H., Garcia, A. L., Bunz, U. H. F., (2007) Bioconjugate Chem., 18, pp. 815-820

Choi, H., Choi, S. R., Zhou, R., Kung, H. F., Chen, I. W., (2004) Acad. Radiol., 11, pp. 996-1004

Low, P. S., Henne, W. A., Doorneweerd, D. D., (2008) Acc. Chem. Res., 41, pp. 120-129



Highly ordered two or three dimensional mesophases in aqueous solution could be usefully obtained by using monoolein (MO) or diolein (DO) monomers. Nanostructures (also indicated as nanoparticles, NPs) of MO or DO containing different amounts (1%, 5%, 10% and 20%) of the synthetic amphiphilic gadolinium complex (C18)2DTPA(Gd) have been prepared and characterized for their relaxometric and structural behaviors. The nanostructure is found in the 110-200 nm range for all investigated systems, while the presence of the gadolinium containing monomer produces a partial loss of the cubic symmetry, as shown by Cryo-TEM images of NPs doped with 10% w/w of (C18)2DTPA(Gd). Gadolinium containing nanostructures display high relaxivity values (in the 10-15 mM-1 s-1 range at 25° and 20 MHz, with a further increase at 37 °C for DO based NPs), and interesting relaxometric properties for their possible use as MRI contrast agents. NPs containing 10% w/w of (C18)2DTPA(Gd) (MO3-NPs and DO3-NPs) have been also derivatized by introducing 3% wt of (C18)2-Peg3000-FA to obtain targeted aggregates (MO3-NP-FA, DO3-NP-FA). A preferential uptake efficiency of DO3-NP-FA in IGROV-1 cells with respect to DO-NPs without folic acid is observed, especially when cells are incubated with low concentrations of nanostructures or at short incubation times, thus indicating its potential use as a target-selective delivery system for MRI contrast agents on tumor cells overexpressing the folate receptor. This journal is © The Royal Society of Chemistry 2013.
Nessun risultato.
Nessun risultato.

Ricerca avanzata▼
Contiene: [X]      Estesa     Autori: [X]  Tipo di lavoro: [X]   Data iniziale: Data finale: [X]      Sede: Affiliazione IBB     
    
[Pulisci modulo]
Vai a fine pagina   Versione per copia e incolla facile   Esporta tutto in BibTeX   Esporta tutto in EndNote


Avitabile C, Diaferia C, Della Ventura B, Mercurio FA, Leone M, Roviello V, Saviano M, Velotta R, Morelli G, Accardo A, Romanelli A
* Self-Assembling of Fmoc-GC Peptide Nucleic Acid Dimers into Highly Fluorescent Aggregates (126 visite)
Chemistry (ISSN: 1521-3765electronic, 0947-6539linking), 2018 Mar 26; 24(18): 4729-4735.
Impact Factor: 5.476
Dettagli    Esporta in BibTeX    Esporta in EndNote

Venuta A, Moret F, Dal Poggetto G, Esposito D, Fraix A, Avitabile C, Ungaro F, Malinconico M, Sortino S, Romanelli A, Laurienzo P, Reddi E, Quaglia F
* Shedding light on surface exposition of poly(ethylene glycol) and folate targeting units on nanoparticles of poly(ε-caprolactone) diblock copolymers: Beyond a paradigm (53 visite)
Eur J Pharm Sci (ISSN: 0928-0987), 2018; 111: 177-185.
Impact Factor: 0
Dettagli    Esporta in BibTeX    Esporta in EndNote

Gianolio E, Bardini P, Arena F, Stefania R, Di Gregorio E, Iani R, Aime S
* Gadolinium Retention in the Rat Brain: Assessment of the Amounts of Insoluble Gadolinium-containing Species and Intact Gadolinium Complexes after Repeated Administration of Gadolinium-based Contrast Agents (65 visite)
Radiology (ISSN: 0033-8419, 1527-1315), 2017 Dec; 285(3): 839-849.
Impact Factor: 7.469
Dettagli    Esporta in BibTeX    Esporta in EndNote

Greco A, Albanese S, Auletta L, De Carlo F, Salvatore M, Howard CM, Claudio PP
* Advances in molecular preclinical therapy mediated by imaging (94 visite) (PDF 98 visite)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1827-1936), 2017 Mar; 61(1): 76-94.
Impact Factor: 2.368
Dettagli    Esporta in BibTeX    Esporta in EndNote

Accardo A, Arena F, Gianolio E, Marasco D, Ringhieri P, Boffa C, Bardini P, Aime S, Morelli G
* Diolein based nanostructures as targeted theranostics (191 visite)
J Biomed Nanotechnol (ISSN: 1550-7033), 2016; 12(5): 1076-1088.
Impact Factor: 4.521
Dettagli    Esporta in BibTeX    Esporta in EndNote

Longo DL, Arena F, Consolino L, Minazzi P, Geninatti-crich S, Giovenzana GB, Aime S
* Gd-AAZTA-MADEC, an improved blood pool agent for DCE-MRI studies on mice on 1 T scanners (134 visite)
Biomaterials (ISSN: 0142-9612, 1878-5905electronic), 2015 Oct 16; 75: 47-57.
Impact Factor: 8.387
Dettagli    Esporta in BibTeX    Esporta in EndNote

Calce E, Monfregola L, Saviano M, De Luca S
* HER2-mediated anticancer drug delivery: strategies to prepare targeting ligands highly specific for the receptor (281 visite)
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2015 May 20; 22(21): 2525-2538.
Impact Factor: 3.455
Dettagli    Esporta in BibTeX    Esporta in EndNote

Ringhieri P, Diaferia C, Galdiero S, Palumbo R, Morelli G, Accardo A
* Liposomal doxorubicin doubly functionalized with CCK8 and R8 peptide sequences for selective intracellular drug delivery (203 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617linking), 2015; 21(5): 415-425.
Impact Factor: 1.951
Dettagli    Esporta in BibTeX    Esporta in EndNote

Cohen SS, Riven I, Cortajarena AL, De Rosa L, D'Andrea LD, Regan L, Haran G
* Probing the molecular origin of native-state flexibility in repeat proteins (190 visite)
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 0002-7863print), 2015; 137(32): 10367-10373.
Impact Factor: 13.038
Dettagli    Esporta in BibTeX    Esporta in EndNote

Accardo A, Ringhieri P, Szekely N, Pipich V, Luchini A, Paduano L, Tesauro D
* Structural insights on nanoparticles containing gadolinium complexes as potential theranostic (161 visite)
Colloid Polym Sci (ISSN: 0303-402x), 2014 May; 292(5): 1121-1127.
Impact Factor: 1.865
Dettagli    Esporta in BibTeX    Esporta in EndNote

Nande R, Greco A, Gossman MS, Lopez JP, Claudio L, Salvatore M, Brunetti A, Denvir J, Howard CM, Claudio PP
* Microbubble-assisted p53, RB, and p130 gene transfer in combination with radiation therapy in prostate cancer (211 visite)
Current Gene Therapy (ISSN: 1875-5631, 1566-5232), 2013 Jun 1; 13(3): 163-174.
Impact Factor: 4.906
Dettagli    Esporta in BibTeX    Esporta in EndNote

Malgieri G, Zaccaro L, Leone M, Bucci E, Esposito S, Baglivo I, Del Gatto A, Russo L, Scandurra R, Pedone PV, Fattorusso R, Isernia C
* Zinc to Cadmium Replacement in the A. thaliana SUPERMAN Cys(2)His(2) Zinc Finger Induces Structural Rearrangements of Typical DNA Base Determinant Positions (165 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2011 Nov; 95(11): 801-810.
Impact Factor: 2.87
Dettagli    Esporta in BibTeX    Esporta in EndNote

Accardo A, Morisco A, Gianolio E, Tesauro D, Mangiapia G, Radulescu A, Brandt A, Morelli G
* Nanoparticles containing octreotide peptides and gadolinium complexes for MRI applications (233 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2011 Feb; 17(2): 154-162.
Impact Factor: 1.799
Dettagli    Esporta in BibTeX    Esporta in EndNote

Accardo A, Morisco A, Tesauro D, Pedone C, Morelli G
* Naposomes: A new class of peptide-derivatized, target-selective multimodal nanoparticles for imaging and therapeutic applications (208 visite)
Ther Deliv (ISSN: 2041-5990), 2011 Feb; 2(2): 235-257.
Impact Factor: 0
Dettagli    Esporta in BibTeX    Esporta in EndNote

Accardo A, Tesauro D, Aloj L, Pedone C, Morelli G
* Supramolecular aggregates containing lipophilic Gd(III) complexes as contrast agents in MRI (127 visite)
Coord Chem Rev (ISSN: 0010-8545), 2009 Sep; 253(17-18): 2193-2213.
Impact Factor: 11.225
Dettagli    Esporta in BibTeX    Esporta in EndNote

Accardo A, Tesauro D, Morisco A, Mangiapia G, Vaccaro M, Gianolio E, Heenan RK, Paduano L, Morelli G
* Micelles obtained by aggregation of gemini surfactants containing the CCK8 peptide and a gadolinium complex (200 visite)
J Biol Inorg Chem (ISSN: 0949-8257, 1432-1327electronic, 0949-8257linking), 2009 May; 14(4): 587-599.
Impact Factor: 3.415
Dettagli    Esporta in BibTeX    Esporta in EndNote

Zaccaro L, Del Gatto A, Pedone C, Saviano M
* Peptides for tumour therapy and diagnosis: current status and future directions (259 visite)
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2009 Mar; 16(7): 780-795.
Impact Factor: 4.708
Dettagli    Esporta in BibTeX    Esporta in EndNote

Vaccaro M, Mangiapia G, Radulescu A, Schillen K, D'Errico G, Morelli G, Paduano L
* Colloidal particles composed of amphiphilic molecules binding gadolinium complexes and peptides as tumor-specific contrast agents in MRI: physico-chemical characterization (265 visite)
Soft Matter (ISSN: 1744-683x), 2009; 5(13): 2504-2512.
Impact Factor: 4.869
Dettagli    Esporta in BibTeX    Esporta in EndNote

Vaccaro M, Mangiapia G, Accardo A, Tesauro D, Gianolio E, Frielinghaus H, Morelli G, Paduano L
* Polymerized mixed aggregates containing gadolinium complex and CCK8 peptide (146 visite)
Colloid Polym Sci (ISSN: 0303-402x), 2008 Dec; 286(14-15): 1643-1652.
Impact Factor: 1.736
Dettagli    Esporta in BibTeX    Esporta in EndNote

Accardo A, Tesauro D, Benedetti E, Pedone C, Morelli G
* Naposomes: A new class of peptide containing supramolecular aggregates as target selective delivery systems (111 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2008 Sep; 14(8): N/D-N/D.
Impact Factor: 1.654
Dettagli    Esporta in BibTeX    Esporta in EndNote

Vaccaro M, Mangiapia G, Paduano L, Gianolio E, Accardo A, Tesauro D, Morelli G
* Structural and relaxometric characterization of peptide aggregates containing gadolinium complexes as potential selective contrast agents in MRI (177 visite)
Chemphyschem (ISSN: 1439-4235, 1439-7641, 1439-7641electronic), 2007 Dec 3; 8(17): 2526-2538.
Impact Factor: 3.502
Dettagli    Esporta in BibTeX    Esporta in EndNote

Del Vecchio S, Zannetti A, Fonti R, Pace L, Salvatore M
* Nuclear imaging in cancer theranostics (287 visite)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2007 Jun; 51(2): 152-163.
Impact Factor: 1.724
Dettagli    Esporta in BibTeX    Esporta in EndNote

Tesauro D, Accardo A, Gianolio E, Paduano L, Teixeira J, Schillén K, Aime S, Morelli G
* Peptide derivatized lamellar aggregates as target-specific MRI contrast agents (188 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2007 May 25; 8(8): 950-955.
Impact Factor: 3.446
Dettagli    Esporta in BibTeX    Esporta in EndNote

Accardo A, Tesauro D, Morelli G, Gianolio E, Aime S, Vaccaro M, Mangiapia G, Paduano L, Schillén K
* High-relaxivity supramolecular aggregates containing peptides and Gd complexes as contrast agents in MRI (184 visite)
J Biol Inorg Chem (ISSN: 0949-8257, 1432-1327electronic, 0949-8257print), 2007 Feb; 12(2): 267-276.
Impact Factor: 3.325
Dettagli    Esporta in BibTeX    Esporta in EndNote

Cucinotta V, Giuffrida A, Grasso G, Maccarrone G, Messina M, Vecchio G
* High selectivity in new chiral separations of dansyl amino acids by cyclodextrin derivatives in electrokinetic chromatography (144 visite)
J Chromatogr A (ISSN: 0021-9673), 2007; 1155(2): 172-179.
Impact Factor: 3.641
Dettagli    Esporta in BibTeX    Esporta in EndNote

Vaccaro M, Accardo A, Tesauro D, Mangiapia G, Loef D, Schillen K, Soederman O, Morelli G, Paduan L
* Supramolecular aggregates of amphiphilic gadolinium complexes as blood pool MRI/MRA contrast agents: Physicochemical characterization (154 visite)
Langmuir (ISSN: 0743-7463), 2006 Jul 18; 22(15): 6635-6643.
Impact Factor: 3.902
Dettagli    Esporta in BibTeX    Esporta in EndNote

Pappalardo M, Milardi D, Grasso D, La Rosa C
* Phase behaviour of polymer-grafted DPPC membranes for drug delivery systems design (116 visite)
Journal Of Thermal Analysis And Calorimetry (ISSN: 1388-6150), 2005 May; 80(2): 413-418.
Impact Factor: 1.425
Dettagli    Esporta in BibTeX    Esporta in EndNote

Morelli G, Accardo A, Tesauro D, Pedone C, Mangiapia G, Paduano L, Gianolio E
* Multicomponent aggregates containing the CCK8 bioactive peptide and Gd complexes as target-specific MRI contrast agents (113 visite)
Peptides 2004 Proceedings, 2005; N/D: N/D-N/D.
Impact Factor: 0
Dettagli    Esporta in BibTeX    Esporta in EndNote

Mangiapia G, Accardo A, Celso FL, Tesauro D, Morelli G, Radulescu A, Paduano L
* Mixed micelles composed of peptides and gadolinium complexes as tumor-specific contrast agents in MRI: A sans study (196 visite)
J Phys Chem B (ISSN: 1520-6106, 1520-5207, 1520-5207electronic), 2004; 108(45): 17611-17617.
Impact Factor: 3.834
Dettagli    Esporta in BibTeX    Esporta in EndNote

Borgatti M, Breda L, Cortesi R, Nastruzzi C, Romanelli A, Saviano M, Bianchi N, Mischiati C, Pedone C, Gambari R
* Cationic Liposomes As Delivery Systems For Double-Stranded Pna-Dna Chimeras Exhibiting Decoy Activity Against Nf-Kappab Transcription Factors (117 visite)
Biochem Pharmacol Biochemical Pharmacology (ISSN: 1873-2968, 0006-2952), 2002 Sep 15; 64(4): 609-616.
Impact Factor: 3.542
Dettagli    Esporta in BibTeX    Esporta in EndNote

Li PY, Del Vecchio S, Fonti R, Carriero MV, Potena MI, Botti G, Miotti S, Lastoria S, Menard S, Colnaghi MI, Salvatore M
Local concentration of folate binding protein GP38 in sections of human ovarian carcinoma by in vitro quantitative autoradiography (176 visite)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1996 Apr; 37(4-6): 665-672.
Impact Factor: 3.491
Dettagli    Esporta in BibTeX    Esporta in EndNote



31 Records (29 escludendo Abstract e Conferenze).
Impact factor totale: 117.544 (115.89 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 124.034 (122.252 escludendo Abstract e Conferenze).







    Esporta in BibTeX    Esporta in EndNote