Nanostructures based on monoolein or diolein and amphiphilic gadolinium complexes as MRI contrast agents
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Nanostructures based on monoolein or diolein and amphiphilic gadolinium complexes as MRI contrast agents (152 visite)

Accardo A, Gianolio E, Arena F, Barnert S, Schubert R, Tesauro D, Morelli G

J Mater Chem B (ISSN: 2050-7518, 2050-750x), 2013; 1(5): 617-628.



Tipo di articolo: Journal Article,

Impact factor: 8.535, Impact factor a 5 anni: 8.419

Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84876529807&partnerID=40&md5=940d1a0b5a9a34825d4386fa3e3fd078

Parole chiave: Delivery Systems, Folate Receptor, Gadolinium Complexes, Low Concentrations, Mri Contrast Agents, Relaxometric Properties, Short Incubations, Structural Behaviors, Doping (additives), Gadolinium Compounds, Monomers, Organic Acids, Nanostructures,

Affiliazioni:

*** IBB - CNR ***
CIRPeB, Department of Pharmacy, University of Naples Federico II, Via Mezzocannone, 16, 80134 Napoli, Italy
Department of Chemistry I.F.M., Molecular Imaging Centre, University of Turin, Via Nizza, 52, 10125 Turin, Italy


Riferimenti:

Young, I.R., (2000) Methods in Biomedical Magnetic Resonance Imaging and Spectroscopy, , John Wiley & Sons Ltd., Chicheste

Rinck, P.A., (2003) Magnetic Resonance in Medicine, , ABW Wissenschaftsverlag GmbH, Berlin

Li, J., Zheng, D., Bae, K.T., Woodard, P.K., Haacke, E.M., (1998) Invest. Radiol., 33, pp. 578-586

Mühler, A., (1998) Invest. Radiol., 33, pp. 709-714

Mühler, A., (1995) MAGMA, 3, pp. 21-33

Delli Castelli, D., Gianolio, E., Geninatti Crich, S., Terreno, E., Aime, S., (2008) Coord. Chem. Rev., 252, pp. 2424-2443

Mulder, W.J.M., Strijkers, G.J., Van Tilborg, G.A.F., Cormode, D.P., Fayad, Z.A., Nicolay, K., (2009) Acc. Chem. Res., 42, pp. 904-914

Accardo, A., Tesauro, D., Aloj, L., Pedone, C., Morelli, G., (2009) Coord. Chem. Rev., 253 (1718), pp. 2193-2213

Tesauro, D., Accardo, A., Gianolio, E., Paduano, L., Texeira, J., Schillen, K., Aime, S., Morelli, G., (2007) ChemBioChem, 8, pp. 950-955

Mulder, W.J.M., Van Der Schaft, D.W.J., Hautvast, P.A.I., Strijkers, G.J., Koning, G.A., Storm, G., Mayo, K.H., Nicolay, K., (2007) FASEB J, 21 (2), pp. 378-383

Brandwijk, R.J.M.G.E., Mulder, W.J.M., Nicolay, K., Mayo, K.H., Thijssen, V.L.J.L., Griffioen, A.W., (2007) Bioconjugate Chem., 18, pp. 785-790

Vaccaro, M., Mangiapia, G., Paduano, L., Gianolio, E., Accardo, A., Tesauro, D., Morelli, G., (2007) ChemPhysChem, 8, pp. 2526-2538

Lipinski, M.J., Amirbekian, V., Frias, J.C., Aguinado, J.G.S., Mani, V., Briley-Saebo, K.C., Fuster, V., Fayad, Z.A., (2006) Magn. Reson. Med., 56 (3), pp. 601-610

Amirbekian, V., Lipinski, M.J., Briley-Saebo, K.C., Amirbekian, S., Aguinado, J.G.S., Weinreb, D.B., Vucic, E., Fayad, Z.A., (2007) Proc. Natl. Acad. Sci. U. S. A., 104 (3), pp. 961-966

Yaghmur, A., Glatter, O., (2009) Adv. Colloid Interface Sci., 147-148, pp. 333-342

Liu, G., Conn, C.E., Waddington, L.J., Mudie, S.T., Drummond, C.J., (2010) Langmuir, 26 (4), pp. 2383-2391

Conn, C.E., Panchagnula, V., Weerawardena, A., Waddington, L.J., Kennedy, D.F., Drummond, C.J., (2010) Langmuir, 26 (9), pp. 6240-6249

Moghaddam, M.J., De Campo, L., Waddington, L.J., Weerawardena, A., Kirby, N., Drummond, C.J., (2011) Soft Matter, 7, pp. 10994-11005

Accardo, A., Morisco, A., Gianolio, E., Tesauro, D., Mangiapia, G., Radulescu, A., Brandte, A., Morelli, G., (2011) J. Pept. Sci., 17, pp. 154-162

Schmitt, L., Dietrich, C., Tampe, R., (1994) J. Am. Chem. Soc., 116, pp. 8485-8491

Sharma, S.K., Lown, J.W., (2002) Tetrahedron Lett., 43, pp. 6665-6667

Dubochet, J., Adrian, M., Chang, J.J., Homo, J.C., Lepault, J., McDowall, A.W., Schultz, P., (1988) Q. Rev. Biophys., 21, pp. 129-228

Talmon, Y., (1996) Ber. Bunsenges. Phys. Chem., 100, pp. 364-372

Rank, A., Hauschild, S., Förster, S., Schubert, R., (2009) Langmuir, 25, pp. 1337-1344

Arena, F., Jebasingh, B.S., Gianolio, E., Stefania, R., Aime, S., (2011) Bioconjugate Chem., 22, pp. 2625-2635

Bradford, M.M., (1976) Anal. Biochem., 72, pp. 248-254

Gustafsson, J., Ljusberg-Wahren, H., Almgren, M., Larsson, K., (1997) Langmuir, 13, pp. 6964-6971

Spicer, P.T., Hayden, K.L., Lynch, M.L., Ofori-Boateng, A., Burns, J.L., (2001) Langmuir, 17 (13), pp. 5748-5756

Solomon, I., (1955) Phys. Rev., 99, pp. 559-565

Bloembergen, N., (1957) J. Chem. Phys., 27, pp. 572-573

Bloembergen, N., Morgan, L.O., (1961) J. Chem. Phys., 34, pp. 842-850

Aime, S., Botta, M., Fasano, M., Terreno, E., (2001) The Chemistry of Contrast Agents in Medical Magnetic Resonance Imaging, p. 5. , ed. A. E. Merbach and E. Toth, John Wiley & Sons LTD

Bertini, I., Luchinat, C., (1996) Coord. Chem. Rev., 50, pp. 1-300

Kamaly, N., Kalber, T., Thanaou, M., Bell, D.J., Miller, A.D., (2009) Bioconjugate Chem., 20, pp. 648-655

Mangiapia, G., Vaccaro, M., D'Errico, G., Frielinghaus, H., Radulescu, A., Pipich, V., Carnerup, A.M., Paduano, L., (2011) Soft Matter, 7, pp. 10577-10580

Hilgenbrik, A.R., Low, P.S., (2005) J. Pharm. Sci., 94, pp. 2135-2142

Sega, E.I., Low, P.S., (2008) Cancer Metastasis Rev., 27, pp. 655-664

Kim, I.B., Shin, H., Garcia, A.L., Bunz, U.H.F., (2007) Bioconjugate Chem., 18, pp. 815-820

Choi, H., Choi, S.R., Zhou, R., Kung, H.F., Chen, I.W., (2004) Acad. Radiol., 11, pp. 996-1004

Ding, N., Lu, Y., Lee, R., Yang, C., Huang, L., Liu, J., Xiang, G., (2011) Int. J. Nanomed., 6, pp. 2513-2520

Low, P.S., Henne, W.A., Doorneweerd, D.D., (2008) Acc. Chem. Res., 41, pp. 120-129

Barauskas, J., Cervin, C., Jankunenc, M., Spandyreva, M., Ribokaite, K., Tiberg, F., Johnsson, M., (2010) Int. J. Pharm., 391, pp. 284-291

Murgia, S., Falchi, A.M., Mano, M., Lampis, S., Angius, R., Carnerup, A.M., Schmidt, J., Monduzzi, M., (2010) J. Phys. Chem. B, 114, pp. 3518-3525

Sahay, G., Batrakova, E.V., Kabanov, A.V., (2008) Bioconjugate Chem., 19, pp. 2023-2029

Li, X., Chen, D., Le, C., Zhu, C., Gang, Y., Hovgaard, L., Yang, M., (2011) Int. J. Nanomed., 6, pp. 3151-3162

Young, I. R., (2000) Methods in Biomedical Magnetic Resonance Imaging and Spectroscopy, , John Wiley & Sons Ltd., Chicheste

Rinck, P. A., (2003) Magnetic Resonance in Medicine, , ABW Wissenschaftsverlag GmbH, Berlin

M hler, A., (1998) Invest. Radiol., 33, pp. 709-714

M hler, A., (1995) MAGMA, 3, pp. 21-33

Mulder, W. J. M., Strijkers, G. J., Van Tilborg, G. A. F., Cormode, D. P., Fayad, Z. A., Nicolay, K., (2009) Acc. Chem. Res., 42, pp. 904-914

Mulder, W. J. M., Van Der Schaft, D. W. J., Hautvast, P. A. I., Strijkers, G. J., Koning, G. A., Storm, G., Mayo, K. H., Nicolay, K., (2007) FASEB J, 21 (2), pp. 378-383

Brandwijk, R. J. M. G. E., Mulder, W. J. M., Nicolay, K., Mayo, K. H., Thijssen, V. L. J. L., Griffioen, A. W., (2007) Bioconjugate Chem., 18, pp. 785-790

Lipinski, M. J., Amirbekian, V., Frias, J. C., Aguinado, J. G. S., Mani, V., Briley-Saebo, K. C., Fuster, V., Fayad, Z. A., (2006) Magn. Reson. Med., 56 (3), pp. 601-610

Liu, G., Conn, C. E., Waddington, L. J., Mudie, S. T., Drummond, C. J., (2010) Langmuir, 26 (4), pp. 2383-2391

Conn, C. E., Panchagnula, V., Weerawardena, A., Waddington, L. J., Kennedy, D. F., Drummond, C. J., (2010) Langmuir, 26 (9), pp. 6240-6249

Moghaddam, M. J., De Campo, L., Waddington, L. J., Weerawardena, A., Kirby, N., Drummond, C. J., (2011) Soft Matter, 7, pp. 10994-11005

Sharma, S. K., Lown, J. W., (2002) Tetrahedron Lett., 43, pp. 6665-6667

Bradford, M. M., (1976) Anal. Biochem., 72, pp. 248-254

Spicer, P. T., Hayden, K. L., Lynch, M. L., Ofori-Boateng, A., Burns, J. L., (2001) Langmuir, 17 (13), pp. 5748-5756

Hilgenbrik, A. R., Low, P. S., (2005) J. Pharm. Sci., 94, pp. 2135-2142

Sega, E. I., Low, P. S., (2008) Cancer Metastasis Rev., 27, pp. 655-664

Kim, I. B., Shin, H., Garcia, A. L., Bunz, U. H. F., (2007) Bioconjugate Chem., 18, pp. 815-820

Choi, H., Choi, S. R., Zhou, R., Kung, H. F., Chen, I. W., (2004) Acad. Radiol., 11, pp. 996-1004

Low, P. S., Henne, W. A., Doorneweerd, D. D., (2008) Acc. Chem. Res., 41, pp. 120-129



Highly ordered two or three dimensional mesophases in aqueous solution could be usefully obtained by using monoolein (MO) or diolein (DO) monomers. Nanostructures (also indicated as nanoparticles, NPs) of MO or DO containing different amounts (1%, 5%, 10% and 20%) of the synthetic amphiphilic gadolinium complex (C18)2DTPA(Gd) have been prepared and characterized for their relaxometric and structural behaviors. The nanostructure is found in the 110-200 nm range for all investigated systems, while the presence of the gadolinium containing monomer produces a partial loss of the cubic symmetry, as shown by Cryo-TEM images of NPs doped with 10% w/w of (C18)2DTPA(Gd). Gadolinium containing nanostructures display high relaxivity values (in the 10-15 mM-1 s-1 range at 25° and 20 MHz, with a further increase at 37 °C for DO based NPs), and interesting relaxometric properties for their possible use as MRI contrast agents. NPs containing 10% w/w of (C18)2DTPA(Gd) (MO3-NPs and DO3-NPs) have been also derivatized by introducing 3% wt of (C18)2-Peg3000-FA to obtain targeted aggregates (MO3-NP-FA, DO3-NP-FA). A preferential uptake efficiency of DO3-NP-FA in IGROV-1 cells with respect to DO-NPs without folic acid is observed, especially when cells are incubated with low concentrations of nanostructures or at short incubation times, thus indicating its potential use as a target-selective delivery system for MRI contrast agents on tumor cells overexpressing the folate receptor. This journal is © The Royal Society of Chemistry 2013.
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31 Records (29 escludendo Abstract e Conferenze).
Impact factor totale: 117.544 (115.89 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 124.034 (122.252 escludendo Abstract e Conferenze).







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