A facile solid-phase strategy for the synthesis of oligonucleotide- tetraphenylporphyrin conjugates(318 views visite) De Napoli L, De Luca S, Di Fabio G, Messere A, Montesarchio D, Morelli G, Piccialli G, Tesauro D
European Journal Of Organic Chemistry (ISSN: 1434-193x), 2000; (6): 1013-1018.
Keywords Parole chiave: Conjugation, Oligonucleotides, Porphyrinoids, Solid-Phase Synthesis, Complementary Dna, Dna Fragment, Lysine Derivative, Polymer, Tetraphenylporphyrin, Article, Dna Denaturation, Hybridization, Solid State, Thermal Analysis, Ultraviolet Spectroscopy,
Affiliations Affiliazioni: Dipto. di Chim. Organica e Biologica, Univ. Studi di Napoli Federico II, Via Mezzocannone 16, 80134 Napoli, Italy Ctro. Interuniversitario Ric. P., Ctro. di Studi di Biocristallografia, Via Mezzocannone 4, 80134 Napoli, Italy Università del Molise, Facoltà di Scienze, Via Mazzini 8, 86170 Isernia, Italy Universit del Molise, Facolt di Scienze, Via Mazzini 8, 86170 Isernia, Italy
References Riferimenti: Le Doan, T., Perroault, L., Hélène, C., (1986) Biochemistry, 25, p. 673
Ramalho Ortigao, J. F., Ruck, A., Gupta, K. C., Rosch, R., Steiner, R., Seliger, H., (1994) Biochimie, 75, p. 29
Moser, H. E., Dervan, P. B., (1987) Science, 238, p. 645
Thuong, N. T., H l ne, C., (1993) Angew. Chem. Int. Engl. Ed., 32, p. 666
Fiel, R. J., Howard, J. C., Mark, E. H., Datta-Gupta, N., (1979) Nucleic Acids Res., 6, p. 3093
Sigman, D. S., Mazumder, A., Perrin, D. M., (1993) Chem. Rev., 93, p. 2295. , and references cited therein
Piti, M., Casas, C., Lacey, C. J., Pratviel, G., Bernadou, J., Meunier, B., (1993) Angew. Chem. Int. Ed. Engl., 32, p. 557
Piti, M., Bernadou, J., Meunier, B., (1995) J. Am. Chem. Soc., 117, p. 2935
Fiel, J. R., Beerman, T. A., Mark, E. H., Datta-Gupta, N., (1982) Biochem. Biophys. Res. Commun., 107, p. 1067
Sessler, J. L., Sansom, P. I., Kral, V., O'Connor, D., Iverson, B. L., (1996) J. Am. Chem. Soc., 118, p. 12322
Sarin, V. K., Kent, S. B. H., Tam, J. P., Merrifield, R. B., (1981) Analytical Biochem., 117, p. 147
Lindsey, J. S., Wagner, R. W., (1989) J. Org. Chem., 54, p. 828
noteFasman, G. D., (1975) Handbook of Biochemistry and Molecular Biology, Volume I, Nucleic Acids, 1, p. 589. , 3rd ed., CRC Press
Cantor, C. R., Warshaw, M. M., Shapiro, H., (1970) Biopolymers, 9, p. 1059
A facile solid-phase strategy for the synthesis of oligonucleotide- tetraphenylporphyrin conjugates
A convenient solid-phase synthesis of oligonucleotides conjugated at the 3'-end with a tetraphenylporphyrin residue, by means of a new polymeric support bearing as a linker a lysine derivative, has been developed. A porphyrin linked 17-mer, designed for antisense experiments, has been prepared in good yields, and its hybridization properties with a complementary DNA fragment evaluated by UV thermal analysis.
A facile solid-phase strategy for the synthesis of oligonucleotide- tetraphenylporphyrin conjugates
Kim YH, Shin SW, Pellicano R, Fagoonee S, Choi IJ, Kim YI, Park B, Choi JM, Kim SG, Choi J, Park JY, Oh S, Yang HJ, Lim JH, Im JP, Kim JS, Jung HC, Ponzetto A, Figura N, Malfertheiner P, Choi IJ, Kook MC, Kim YI, Cho SJ, Lee JY, Kim CG, Park B, Nam BH, Bae SE, Choi KD, Choe J, Kim SO, Na HK, Choi JY, Ahn JY, Jung KW, Lee J, Kim DH, Chang HS, Song HJ, Lee GH, Jung HY, Seta T, Takahashi Y, Noguchi Y, Shikata S, Sakai T, Sakai K, Yamashita Y, Nakayama T, Leja M, Park JY, Murillo R, Liepniece-karele I, Isajevs S, Kikuste I, Rudzite D, Krike P, Parshutin S, Polaka I, Kirsners A, Santare D, Folkmanis V, Daugule I, Plummer M, Herrero R, Tsukamoto T, Nakagawa M, Kiriyama Y, Toyoda T, Cao X, Corral JE, Mera R, Dye CW, Morgan DR, Lee YC, Lin JT, Garcia Martin R, Matia Cubillo A, Lee SH, Park JM, Han YM, Ko WJ, Hahm KB, Leontiadis GI, Ford AC, Ichinose M, Sugano K, Jeong M, Park JM, Han YM, Park KY, Lee DH, Yoo JH, Cho JY, Hahm KB, Bang CS, Baik GH, Shin IS, Kim JB, Suk KT, Yoon JH, Kim YS, Kim DJ * Helicobacter pylori Eradication for Prevention of Metachronous Recurrence after Endoscopic Resection of Early Gastric Cancer(238 visite) N Engl J Med (ISSN: 0028-4793, 0028-4793linking, 1533-4406electronic), 2015 Jun; 30642104201566393291: 749-756. Impact Factor:59.558 DettagliEsporta in BibTeXEsporta in EndNote
182 Records (176 escludendo Abstract e Conferenze). Impact factor totale: 811.621 (794.733 escludendo Abstract e Conferenze). Impact factor a 5 anni totale: 826.148 (804.465 escludendo Abstract e Conferenze).
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