Keywords Parole chiave: Intensity Modulation, Protons, X-Rays, Beam Therapy, Cancer Radiotherapy, Case Report, Child, Conference Paper, Controlled Study, Human, Prostate Cancer, Proton Radiation, Radiation Dose Distribution, Rhabdomyosarcoma, Tumor Volume, Dose-Response Relationship, Neoplasms, Second Primary, Organ Specificity, Prostatic Neoplasms, Radiation Dosage, Radiation Tolerance,
Affiliations Affiliazioni: *** IBB - CNR ***
Dipartimento di Scienze Fisiche, Università di Napoli, Napoli, Italy
References Riferimenti: Lomax, A., Intensity modulation methods for proton radiotherapy (1999) Phys Med Biol, 44, pp. 185-20
Bortfeld, T., Buerkelbach, J., Boesecke, R., Schlegel, W., Three-dimensional solution of the inverse problem in conformation radiotherapy (1992), pp. 503-508. , Breit A. ed. Advanced radiation therapy: Tumor response monitoring and treatment planning. Berlin. Springer VerlagLyman, J.T., Complication probability as assessed from dose-volume histograms (1985) Radiat Res, 104, pp. 513-519
New techniques in hadrontherapy: Intensity modulated proton beams
Inverse planning and intensity modulated (IM) X-ray beam treatment techniques can achieve significant improvements in dose distributions comparable to those obtained with forward planned proton beams. However, intensity modulation can also be applied to proton beams and further optimization in dose distribution can reasonably be expected. A comparative planning exercise between IM X-rays and IM proton beams was carried out on two different tumor cases: a pediatric rhabdomyosarcoma and a prostate cancer. Both IM X-rays and IM protons achieved equally homogenous coverage of the target volume in the two tumor sites. Predicted NTCPs were equally low for both treatment techniques. Nevertheless, a reduced low-to-medium dose to the organs at risk and a lesser integral non-target mean dose for IM protons in the two cases favored the use of IM proton beams.
New techniques in hadrontherapy: Intensity modulated proton beams
No results. Nessun risultato.
New techniques in hadrontherapy: Intensity modulated proton beams
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