Solid-phase synthesis of new Trp(Nps)-containing dipeptide derivatives as TRPV1 channel blockers (144 visite)
Molecules (ISSN: 1420-3049, 1420-3049electronic, 1420-3049linking), 2010 Jul 15; 15(7): 4924-4933.
Tipo di articolo: Journal Article,
Impact factor: 1.988, Impact factor a 5 anni: 1.974
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-77954975254&partnerID=40&md5=6cf34d0eb54b088d9c1fd7bf925922c3
Parole chiave: Solid-Phase, Trp(nps) Dipeptides, Trpv1 Channel Blockers, Alkane, Guanidine, Lysine, Trpv1 Protein, Human, Tryptophan, Vanilloid Receptor, Article, Drug Antagonism, Structure Activity Relation, Synthesis, Structure-Activity Relationship, Trpv Cation Channels, Trp (nps) Dipeptides,
Affiliazioni:
*** IBB - CNR ***
Instituto de Química Médica, CSIC, Juan de la Cierva, 3, 28006 Madrid, Spain
Combinatorial Chemistry Unit, Barcelona Science Park, University of Barcelona, Barcelona 08028, Spain
Institute for Research in Biomedicine, Barcelona Science Park, University of Barcelona, Barcelona 08028, Spain
CIBER-BBN, Networking Centre on Bioengineering Biomaterials and Nanomedicine, Barcelona 08028, Spain
Department of Organic Chemistry, University of Barcelona, Barcelona 08028, Spain
IBMC-UMH, Ed. Torregaitán, Av. de la Universidad s/n, 03202 Elche, Spain
Instituto de Qu mica M dica, CSIC, Juan de la Cierva, 3, 28006 Madrid, Spain
Riferimenti:
Levine, J.D., Alessandri-Haber, N., TRP channels: Targets for the relief of pain (2007) Biochim. Biophys. Acta, 1772, pp. 989-100
Planells-Cases, R., Garcìa-Sanz, N., Morenilla-Palao, C., Ferrer-Montiel, A., Functional aspects and mechanisms of TRPV1 involvement in neurogenic inflammation that leads to thermal hyperalgesia (2005) Pflugers Arch., 451, pp. 151-159
Gunthorpe, M.J., Chizh, B.A., Clinical development of TRPV1 antagonists: Targeting a pivotal point in the pain pathway (2009) Drug Discov. Today, 14, pp. 56-67
Patapoutian, A., Tate, S., Woolf, C.J., Transient receptor potential channels: Targeting pain at the source (2009) Nat. Rev. Drug Discov., 8, pp. 55-68
García-Martínez, C., Morenilla-Palao, C., Planells-Cases, R., Merino, J.M., Ferrer-Montiel, A., Identification of an aspartic residue in the P-loop of the vanilloid receptor that modulates pore properties (2000) J. Biol. Chem., 275, pp. 32552-32558
García-López, M.T., Herranz, R., González-Muñiz, R., Naranjo, J.R., De Ceballos, M., Del Río, J., Antinociceptive effects in rodents of the dipeptide Lys-Trp(Nps) and related compounds (1986) Peptides, 7, pp. 39-43
Bonache, M.A., García-Martínez, C., García De Diego, L., Carreno, C., Pérez De Vega, M.J., García-López, M.T., Ferrer-Montiel, A., González-Muñiz, R., Old molecule for new receptors: Trp(Nps) dipeptide derivatives as vanilloid TRPV1 channel blockers (2006) ChemMedChem, 1, pp. 429-438
Szardenings, A.K., Burtoth, T.S., Look, G.C., Campbell, D.A.A., Reductive alkylation procedure applicable to both solution- and solid-phase syntheses of secondary amines (1996) J. Org. Chem., 61, pp. 6720-6722
Shey, J.-Y., Sun, C.-M., Soluble polymer supported synthesis of N,N-di(Boc)-protected guanidines (1998) Synlett, pp. 1423-1425
Del Fresno, M., El-Faham, A., Carpino, L.A., Royo, M., Albericio, F., Substituted guanidines: Introducing diversity in combinatorial chemistry (2000) Org. Lett., 2, pp. 3539-3542
Farrera-Sinfreu, J., Royo, M., Albericio, F., Undesired removal of the Fmoc group by the free ε-amino function of a lysine residue (2002) Tetrahedron Lett., 43, pp. 7813-7815
Levine, J. D., Alessandri-Haber, N., TRP channels: Targets for the relief of pain (2007) Biochim. Biophys. Acta, 1772, pp. 989-100
Gunthorpe, M. J., Chizh, B. A., Clinical development of TRPV1 antagonists: Targeting a pivotal point in the pain pathway (2009) Drug Discov. Today, 14, pp. 56-67
Garc a-Mart nez, C., Morenilla-Palao, C., Planells-Cases, R., Merino, J. M., Ferrer-Montiel, A., Identification of an aspartic residue in the P-loop of the vanilloid receptor that modulates pore properties (2000) J. Biol. Chem., 275, pp. 32552-32558
Garc a-L pez, M. T., Herranz, R., Gonz lez-Mu iz, R., Naranjo, J. R., De Ceballos, M., Del R o, J., Antinociceptive effects in rodents of the dipeptide Lys-Trp (Nps) and related compounds (1986) Peptides, 7, pp. 39-43
Bonache, M. A., Garc a-Mart nez, C., Garc a De Diego, L., Carreno, C., P rez De Vega, M. J., Garc a-L pez, M. T., Ferrer-Montiel, A., Gonz lez-Mu iz, R., Old molecule for new receptors: Trp (Nps) dipeptide derivatives as vanilloid TRPV1 channel blockers (2006) ChemMedChem, 1, pp. 429-438
Szardenings, A. K., Burtoth, T. S., Look, G. C., Campbell, D. A. A., Reductive alkylation procedure applicable to both solution- and solid-phase syntheses of secondary amines (1996) J. Org. Chem., 61, pp. 6720-6722
Shey, J. -Y., Sun, C. -M., Soluble polymer supported synthesis of N, N-di (Boc) -protected guanidines (1998) Synlett, pp. 1423-1425
Molecules (ISSN: 1420-3049, 1420-3049electronic, 1420-3049linking), 2010 Jul 15; 15(7): 4924-4933.
Tipo di articolo: Journal Article,
Impact factor: 1.988, Impact factor a 5 anni: 1.974
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-77954975254&partnerID=40&md5=6cf34d0eb54b088d9c1fd7bf925922c3
Parole chiave: Solid-Phase, Trp(nps) Dipeptides, Trpv1 Channel Blockers, Alkane, Guanidine, Lysine, Trpv1 Protein, Human, Tryptophan, Vanilloid Receptor, Article, Drug Antagonism, Structure Activity Relation, Synthesis, Structure-Activity Relationship, Trpv Cation Channels, Trp (nps) Dipeptides,
Affiliazioni:
*** IBB - CNR ***
Instituto de Química Médica, CSIC, Juan de la Cierva, 3, 28006 Madrid, Spain
Combinatorial Chemistry Unit, Barcelona Science Park, University of Barcelona, Barcelona 08028, Spain
Institute for Research in Biomedicine, Barcelona Science Park, University of Barcelona, Barcelona 08028, Spain
CIBER-BBN, Networking Centre on Bioengineering Biomaterials and Nanomedicine, Barcelona 08028, Spain
Department of Organic Chemistry, University of Barcelona, Barcelona 08028, Spain
IBMC-UMH, Ed. Torregaitán, Av. de la Universidad s/n, 03202 Elche, Spain
Instituto de Qu mica M dica, CSIC, Juan de la Cierva, 3, 28006 Madrid, Spain
Riferimenti:
Levine, J.D., Alessandri-Haber, N., TRP channels: Targets for the relief of pain (2007) Biochim. Biophys. Acta, 1772, pp. 989-100
Planells-Cases, R., Garcìa-Sanz, N., Morenilla-Palao, C., Ferrer-Montiel, A., Functional aspects and mechanisms of TRPV1 involvement in neurogenic inflammation that leads to thermal hyperalgesia (2005) Pflugers Arch., 451, pp. 151-159
Gunthorpe, M.J., Chizh, B.A., Clinical development of TRPV1 antagonists: Targeting a pivotal point in the pain pathway (2009) Drug Discov. Today, 14, pp. 56-67
Patapoutian, A., Tate, S., Woolf, C.J., Transient receptor potential channels: Targeting pain at the source (2009) Nat. Rev. Drug Discov., 8, pp. 55-68
García-Martínez, C., Morenilla-Palao, C., Planells-Cases, R., Merino, J.M., Ferrer-Montiel, A., Identification of an aspartic residue in the P-loop of the vanilloid receptor that modulates pore properties (2000) J. Biol. Chem., 275, pp. 32552-32558
García-López, M.T., Herranz, R., González-Muñiz, R., Naranjo, J.R., De Ceballos, M., Del Río, J., Antinociceptive effects in rodents of the dipeptide Lys-Trp(Nps) and related compounds (1986) Peptides, 7, pp. 39-43
Bonache, M.A., García-Martínez, C., García De Diego, L., Carreno, C., Pérez De Vega, M.J., García-López, M.T., Ferrer-Montiel, A., González-Muñiz, R., Old molecule for new receptors: Trp(Nps) dipeptide derivatives as vanilloid TRPV1 channel blockers (2006) ChemMedChem, 1, pp. 429-438
Szardenings, A.K., Burtoth, T.S., Look, G.C., Campbell, D.A.A., Reductive alkylation procedure applicable to both solution- and solid-phase syntheses of secondary amines (1996) J. Org. Chem., 61, pp. 6720-6722
Shey, J.-Y., Sun, C.-M., Soluble polymer supported synthesis of N,N-di(Boc)-protected guanidines (1998) Synlett, pp. 1423-1425
Del Fresno, M., El-Faham, A., Carpino, L.A., Royo, M., Albericio, F., Substituted guanidines: Introducing diversity in combinatorial chemistry (2000) Org. Lett., 2, pp. 3539-3542
Farrera-Sinfreu, J., Royo, M., Albericio, F., Undesired removal of the Fmoc group by the free ε-amino function of a lysine residue (2002) Tetrahedron Lett., 43, pp. 7813-7815
Levine, J. D., Alessandri-Haber, N., TRP channels: Targets for the relief of pain (2007) Biochim. Biophys. Acta, 1772, pp. 989-100
Gunthorpe, M. J., Chizh, B. A., Clinical development of TRPV1 antagonists: Targeting a pivotal point in the pain pathway (2009) Drug Discov. Today, 14, pp. 56-67
Garc a-Mart nez, C., Morenilla-Palao, C., Planells-Cases, R., Merino, J. M., Ferrer-Montiel, A., Identification of an aspartic residue in the P-loop of the vanilloid receptor that modulates pore properties (2000) J. Biol. Chem., 275, pp. 32552-32558
Garc a-L pez, M. T., Herranz, R., Gonz lez-Mu iz, R., Naranjo, J. R., De Ceballos, M., Del R o, J., Antinociceptive effects in rodents of the dipeptide Lys-Trp (Nps) and related compounds (1986) Peptides, 7, pp. 39-43
Bonache, M. A., Garc a-Mart nez, C., Garc a De Diego, L., Carreno, C., P rez De Vega, M. J., Garc a-L pez, M. T., Ferrer-Montiel, A., Gonz lez-Mu iz, R., Old molecule for new receptors: Trp (Nps) dipeptide derivatives as vanilloid TRPV1 channel blockers (2006) ChemMedChem, 1, pp. 429-438
Szardenings, A. K., Burtoth, T. S., Look, G. C., Campbell, D. A. A., Reductive alkylation procedure applicable to both solution- and solid-phase syntheses of secondary amines (1996) J. Org. Chem., 61, pp. 6720-6722
Shey, J. -Y., Sun, C. -M., Soluble polymer supported synthesis of N, N-di (Boc) -protected guanidines (1998) Synlett, pp. 1423-1425
Trp(Nps)-Lys-NH(2) derivatives, bearing alkyl or guanidine groups either at the N-terminus or on the Lys side-chain or at both positions were conveniently prepared on solid-phase and evaluated as TRPV1 channel antagonists.
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Maurea S, Fiumara G, Pellegrino T, Zampella E, Assante R, Mainenti PP, Cuocolo A
* MIBG molecular imaging for evaluating response to chemotherapy in patients with malignant pheochromocytoma: preliminary results (125 visite)
Cancer Imaging (ISSN: 1470-7330, 1470-7330electronic, 1470-7330linking), 2013 Apr 15; 13: 155-161.
Impact Factor: 1.286
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Paolillo S, Rengo G, Pagano G, Pellegrino T, Savarese G, Femminella GD, Tuccillo M, Boemio A, Attena E, Formisano R, Petraglia L, Scopacasa F, Galasso G, Leosco D, Trimarco B, Cuocolo A, Perrone-Filardi P
* IMPACT OF DIABETES MELLITUS IN IODINE-123 META-IODOBENZYLGUANIDINE (I123MIBG) CARDIAC UPTAKE IN PATIENTS WITH HEART FAILURE (136 visite)
Journal Of The American College Of Cardiology (ISSN: 0735-1097), 2013 Mar 12; 61(10): 2395-2401.
Impact Factor: 15.343
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Pica A, Russo Krauss I, Castellano I, La Cara F, Graziano G, Sica F, Merlino A
* Effect Of Nacl On The Conformational Stability Of The Thermophilic Gamma-Glutamyltranspeptidase From Geobacillus Thermodenitrificans: Implication For Globular Protein Halotolerance (135 visite)
Bba-Gen Subjects (ISSN: 1570-9639, 0006-3002, 0925-4439), 2013 Jan; 1834(1): 149-157.
Impact Factor: 3.191
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Pellegrino T, Pappata S, De Rosa A, De Leva M, Tuccillo M, Boemio A, Filla A, De Michele G, Cuocolo A
* Cardiac Metaiodobenzylguanidine Scintigraphy in Patients With Spinocerebellar Ataxia Type (121 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2012 Oct; 39: N/D-N/D.
Impact Factor: 5.114
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Maurea S, Cuocolo A, Imbriaco M, Pellegrino T, Fusari M, Cuocolo R, Liuzzi R, Salvatore M
* Imaging characterization of benign and malignant pheochromocytoma or paraganglioma: comparison between MIBG uptake and MR signal intensity ratio (198 visite)
Ann Nucl Med (ISSN: 1864-6433, 0914-7187, 1864-6433electronic), 2012 Oct; 26(8): 670-675.
Impact Factor: 1.41
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Kaprelyants AS, Mukamolova GV, Ruggiero A, Makarov VA, Demina GR, Shleeva MO, Potapov VD, Shramko PA
* Resuscitation-promoting Factors (Rpf): In Search of Inhibitors (156 visite)
Protein Pept Lett (ISSN: 0929-8665, 1875-5305), 2012 Oct; 19(10): 1026-1034.
Impact Factor: 1.994
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Pica A, Russo Krauss I, Castellano I, Rossi M, La Cara F, Graziano G, Sica F, Merlino A
* Exploring The Unfolding Mechanism Of Gamma-Glutamyltranspeptidases: The Case Of The Thermophilic Enzyme From Geobacillus Thermodenitrificans (191 visite)
Bba-Gen Subjects (ISSN: 1570-9639, 0006-3002, 0925-4439), 2012 Apr; 1824(4): 571-577.
Impact Factor: 3.733
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Merlino A, Russo Krauss I, Rossi B, De Vendittis A, Marco S, De Vendittis E, Vergara A, Sica F
* Identification of an active dimeric intermediate populated during the unfolding process of the cambialistic superoxide dismutase from Streptococcus mutans (152 visite)
Biochimie (ISSN: 0300-9084, 1638-6183, 1638-6183electronic), 2012 Mar; 94(3): 768-775.
Impact Factor: 3.142
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Gringeri CV, Menchise V, Rizzitelli S, Cittadino E, Catanzaro V, Dati G, Chaabane L, Digilio G, Aime S
* Novel Gd(III)-based probes for MR molecular imaging of matrix metalloproteinases (252 visite)
Contrast Media Mol Imaging (ISSN: 1555-4309, 1555-4309linking), 2012 Mar; 7(2): 175-184.
Impact Factor: 2.872
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Falanga A, Tarallo R, Vitiello G, Vitiello M, Perillo E, Cantisani M, D'Errico G, Galdiero M, Galdiero S
* Biophysical Characterization and Membrane Interaction of the Two Fusion Loops of Glycoprotein B from Herpes Simplex Type I Virus (234 visite)
Plosone (ISSN: 1932-6203, 1932-6203electronic), 2012 Feb 23; 7(2): N/D-N/D.
Impact Factor: 3.73
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Esposito L, Ruggiero A, Masullo M, Ruocco MR, Lamberti A, Arcari P, Zagari A, Vitagliano L
* Crystallographic and spectroscopic characterizations of Sulfolobus solfataricus TrxA1 provide insights into the determinants of thioredoxin fold stability (153 visite)
J Struct Biol (ISSN: 1047-8477), 2012 Feb; 177(2): 506-512.
Impact Factor: 3.361
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Galdiero S, Vitiello M, Falanga A, Cantisani M, Incoronato N, Galdiero M
* Intracellular Delivery: Exploiting Viral Membranotropic Peptides (265 visite)
Current Drug Metabolism (ISSN: 1389-2002), 2012 Jan; 13(1): 93-104.
Impact Factor: 4.405
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Perrone-Filardi P, Paolillo S, Dellegrottaglie S, Gargiulo P, Savarese G, Marciano C, Casaretti L, Cecere M, Musella F, Pirozzi E, Parente A, Cuocolo A
* Assessment of cardiac sympathetic activity by MIBG imaging in patients with heart failure: a clinical appraisal (159 visite)
Heart (ISSN: 1468-201x, 1355-6037), 2011 Nov; 97(22): 1828-1833.
Impact Factor: 4.223
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Zaccaro L, Garcia-lopez Mt Gonzalez-muniz RG
* TRPV1 modulators: Structure-activity relationships using a rational combinatorial approach (154 visite)
Bioorganic & Medicinal Chemistry Letters (ISSN: 0960-894x), 2011 Jun 15; 21(12): 3541-3545.
Impact Factor: 2.554
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Basile A, Del Gatto A, Diana D, Di Stasi R, Falco A, Festa M, Rosati A, Barbieri A, Franco R, Arra C, Pedone C, Fattorusso R, Turco MC, D'Andrea LD
* Characterization of a designed vascular endothelial growth factor receptor antagonist helical peptide with antiangiogenic activity in vivo (172 visite)
J Med Chem (ISSN: 1520-4804, 0022-2623, 0022-2623print), 2011 Mar 10; 54(5): 1391-1400.
Impact Factor: 5.248
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Accardo A, Morisco A, Gianolio E, Tesauro D, Mangiapia G, Radulescu A, Brandt A, Morelli G
* Nanoparticles containing octreotide peptides and gadolinium complexes for MRI applications (242 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2011 Feb; 17(2): 154-162.
Impact Factor: 1.799
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Galdiero S, Falanga A, Vitiello M, Raiola L, Russo L, Pedone C, Isernia C, Galdiero M
* The presence of a single N-terminal histidine residue enhances the fusogenic properties of a Membranotropic peptide derived from herpes simplex virus type 1 glycoprotein (140 visite)
J Biol Chem (ISSN: 1083-351x, 0021-9258), 2010 May 28; 285(22): 17123-17136.
Impact Factor: 5.328
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Galdiero S, Falanga A, Vitiello G, Vitiello M, Pedone C, D'Errico G, Galdiero M
* Role of membranotropic sequences from herpes simplex virus type I glycoproteins B and H in the fusion process (162 visite)
Bba-Mol Basis Dis (ISSN: 0006-3002, 0005-2736, 0925-4439), 2010 Mar; 1798(3): 579-591.
Impact Factor: 4.647
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Speranza A, Ortosecco G, Castaldi E, Nardelli A, Pace L, Salvatore M
* Fully automated synthesis procedure of 4-[18F]fluorobenzaldehyde by commercial synthesizer: amino-oxi peptide labelling prosthetic group (171 visite)
Applied Radiation And Isotopes (ISSN: 1872-9800, 0969-8043, 0969-8043linking), 2009 Sep; 67(9): 1664-1669.
Impact Factor: 1.094
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Pennacchio A, Esposito L, Zagari A, Rossi M, Raia CA
* Role of Tryptophan 95 in substrate specificity and structural stability of Sulfolobus solfataricus alcohol dehydrogenase (126 visite)
Extremophiles (ISSN: 1431-0651, 1433-4909, 1433-4909electronic), 2009 Sep; 13(5): 751-761.
Impact Factor: 2
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Galdiero S, Falanga A, Vitiello M, Raiola L, Fattorusso R, Browne H, Pedone C, Isernia C, Galdiero M
* Analysis of a membrane interacting region of herpes simplex virus type 1 glycoprotein (220 visite)
J Biol Chem (ISSN: 0021-9258, 1083-351x), 2008 Oct 31; 283(44): 29993-30009.
Impact Factor: 5.52
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Dudar GK, D'Andrea LD, Di Stasi R, Pedone C, Wallace JL
* A vascular endothelial growth factor mimetic accelerates gastric ulcer healing in an iNOS-dependent manner (173 visite)
Am J Physiol Gastrointest Liver Physiol American Journal Of Physiology Gastrointestinal And Liver Physiology (ISSN: 0193-1857), 2008 Sep; 295(2): G374-G374.
Impact Factor: 3.587
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Pulcrano M, Camera L, Pagano L, Del Vecchio S, Ferone D, Bodei L, Murgia A, Pace L, Storto G, Paganelli G, Colao A, Salvatore M, Lombardi G, Biondi B
* Usefulness of [(111)In-DTPA(0)] octreotide scintigraphy in a family with von Hippel-Lindau disease (184 visite)
J Endocrinol Invest (ISSN: 0391-4097, 1720-8386electronic), 2008 Apr; 31(4): 352-359.
Impact Factor: 1.888
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Staiano M, Saviano M, Herman P, Grycznyski Z, Fini C, Varriale A, Parracino A, Kold AB, Rossi M, D'Auria S
* Time-resolved fluorescence spectroscopy and molecular dynamics simulations point out the effects of pressure on the stability and dynamics of the porcine odorant-binding protein (228 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2008; 89(4): 284-291.
Impact Factor: 2.823
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Ntziachristos V, Cuénod CA, Fournier L, Balvay D, Pradel C, Siauve N, Clement O, Jouannot E, Lucidarme O, Vecchio SD, Salvatore M, Law B, Tung C-H, Jain RK, Fukumura D, Munn LL, Brown EB, Schellenberger E, Montet X, Weissleder R, Clerck ND, Postnov A
* Tumor Imaging (152 visite)
Textbook Of In Vivo Imaging In Vertebrates (ISSN: 9780-4700), 2007 Jul 16; 1: 277-309.
Impact Factor: 1.148
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D'Auria S, Varriale A, Gonnelli M, Saviano M, Staiano M, Rossi M, Strambini GB
* Tryptophan phosphorescence studies of the D-galactose/ D-glucose-binding protein from Escherichia coli provide a molecular portrait with structural and dynamics features of the protein (408 visite)
J Proteome Res (ISSN: 1535-3893), 2007; 6(4): 1306-1312.
Impact Factor: 5.675
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Calvanese L, Saporito A, Marasco D, D'Auria G, Minchiotti G, Pedone C, Paolillo L, Falcigno L, Ruvo M
* Solution structure of mouse Cripto CFC domain and its inactive variant Trp107Ala (139 visite)
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2006 Nov 30; 49(24): 7054-7062.
Impact Factor: 5.115
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Alterio V, Vitale RM, Monti SM, Pedone C, Scozzafava A, Cecchi A, De Simone G, Supuran CT
* Carbonic anhydrase inhibitors: X-ray and molecular modeling study for the interaction of a fluorescent antitumor sulfonamide with isozyme II and IX (151 visite)
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126), 2006 Jun 28; 128(25): 8329-8335.
Impact Factor: 7.696
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D'Andrea LD, Del Gatto A, Pedone C, Benedetti E
* Peptide-based molecules in angiogenesis (207 visite)
Chem Biol Drug Des Chemical Biology And Drug Design (ISSN: 1747-0277, 1747-0285), 2006 Feb; 67(2): 115-126.
Impact Factor: 2.507
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Granata V, Graziano G, Ruggiero A, Raimo G, Masullo M, Arcari P, Vitagliano L, Zagari A
* Chemical Denaturation Of The Elongation Factor 1 Alpha Isolated From The Hyperthermophilic Archaeon Sulfolobus Solfataricus (142 visite)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2006 Jan 24; 45(3): 719-726.
Impact Factor: 3.633
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Bonomo RP, Cucinotta V, Giuffrida A, Impellizzeri G, Magrì A, Pappalardo G, Rizzarelli E, Santoro AM, Tabbì G, Vagliasindi LI
* A re-investigation of copper coordination in the octa-repeats region of the prion protein (180 visite)
Dalton T (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2005 Jan 7; (1): 150-158.
Impact Factor: 3.003
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Zubrzak P, Banas A, Kaczmarek K, Leplawy MT, Sochacki M, Kowalski ML, Szkudlinska B, Zabrocki J, Di Lello P, Isernia C, Saviano M, Pedone C, Benedetti E
* Analogues of cyclolinopeptide A containing alpha-hydroxymethyl amino acid residues (191 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2005; 80(2-3): 347-356.
Impact Factor: 2.425
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De Luca S, Morelli G
* Synthesis and characterization of a sulfated and a non-sulfated cyclic CCK8 analogue functionalized with a chelating group for metal labelling (151 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2004 May; 10(5): 265-273.
Impact Factor: 1.652
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Cucinotta V, Giuffrida A, La Mendola D, Maccarrone G, Puglisi A, Rizzarelli E, Vecchio G
* 3-Amino Derivative Of Beta-Cyclodextrin: Thermodynamics Of Copper (ii) Complexes And Exploitation Of Its Enantioselectivity In The Separation Of Amino Acid Racemates By Ligand Exchange Capillary Electrophoresis (168 visite)
And Life Sciencesjournal Of Chromatography B Analytical Technologies In The Biomedical, 2004 Feb 5; 800(1-2): 127-133.
Impact Factor: 1.403
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Maurea S, Caracò C, Klain M, Mainolfi C, Salvatore M
* Imaging characterization of non-hypersecreting adrenal masses. Comparison between MR and radionuclide techniques (156 visite) (PDF 146 visite)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2004; 48(3): 188-197.
Impact Factor: 1.724
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Mansi R, Tesauro D, De Capua A, Fattorusso R, Carac C, Aloj L, Benedetti E, Morelli G
* Peptide-chelating agent conjugate for selective targeting of somatostatin receptor type 1: Synthesis and characterization (215 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2004; 76(6): 527-534.
Impact Factor: 2.863
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De Luca S, Ragone R, Bracco C, Digilio G, Aloj L, Tesauro D, Saviano M, Pedone C, Morelli G
* A cyclic CCK8 analogue selective for the cholecystokinin type A receptor: design, synthesis, NMR structure and binding measurements (182 visite)
Chembiochem (ISSN: 1439-7633, 1439-4227, 1439-7633electronic), 2003 Nov 7; 4(11): 1176-1187.
Impact Factor: 3.992
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De Simone G, Menchise V, Omaggio S, Pedone C, Scozzafava A, Supuran CT
* Design of weakly basic thrombin inhibitors incorporating novel P1 binding functions: Molecular and X-ray crystallographic studies (150 visite)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2003 Sep 5; 42(30): 9013-9021.
Impact Factor: 3.922
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De Luca S, Ulhaq S, Dixon M J, EssexJ, Bradley M
* Solid-phase synthesis of a focused library of trypanothione reductase inhibitors (160 visite)
Tetrahedron Lett (ISSN: 0040-4039), 2003 Apr 7; 44(15): 3195-3197.
Impact Factor: 2.326
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Maglio O, Nastri F, Pavone V, Lombardi A, Degrado WF
* Preorganization of molecular binding sites in designed diiron proteins (121 visite)
P Natl Acad Sci Usa (ISSN: 0027-8424print, 0027-8424linking), 2003 Apr 1; 100(7): 3772-3777.
Impact Factor: 10.272
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Cucinotta V, Giuffrida A, Grasso G, Maccarrone G, Vecchio G
* Ligand exchange chiral separations by cyclodextrin derivatives in capillary electrophoresis (134 visite)
Analyst (ISSN: 0003-2654), 2003; 128(2): 134-136.
Impact Factor: 2.251
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Morelli G, De Luca S, Tesauro D, Saviano M, Pedone C, Dolmella A, Visentin R, Mazzi U
* CCK8 peptide derivatized with diphenylphosphine for rhenium labelling: Synthesis and molecular mechanics calculations (129 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2002 Jul; 8(7): 373-381.
Impact Factor: 1.691
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Maurea S, Klain M, Mainolfi C, Ziviello M, Salvatore M
* The diagnostic role of radionuclide imaging in evaluation of patients with nonhypersecreting adrenal masses (115 visite) (PDF 146 visite)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2001 Jun; 42(6): 884-892.
Impact Factor: 4.51
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De Napoli L, De Luca S, Di Fabio G, Messere A, Montesarchio D, Morelli G, Piccialli G, Tesauro D
A facile solid-phase strategy for the synthesis of oligonucleotide- tetraphenylporphyrin conjugates (123 visite)
European Journal Of Organic Chemistry (ISSN: 1434-193x), 2000; (6): 1013-1018.
Impact Factor: 2.15
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De Luca S, Bruno G, Fattorusso R, Isernia C, Pedone C, Morelli G
New synthetic tools for peptide-tetraphenylporphyrin derivatives (122 visite)
Int J Pept Res Ther (ISSN: 0929-5666, 1573-3149), 1998 Jul; 5(4): 269-276.
Impact Factor: 0.557
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Bonomo RP, Cucinotta V, D'Alessandro F, Impellizzeri G, Maccarrone G, Rizzarelli E, Vecchio G, Carima L, Corradini R, Sartor G, Marchelli R
Chiral recognition by the copper(ii) complex of 6-deoxy-6-n-(2 - methylaminopyridine)-β-cyclodextrin (137 visite)
Chirality (ISSN: 0899-0042), 1997; 9(4): 341-349.
Impact Factor: 1.915
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Maurea S, Lastoria S, Caracò C, Klain M, Varrella P, Acampa W, Muto P, Salvatore M
The role of radiolabeled somatostatin analogs in adrenal imaging (142 visite)
Nucl Med Biol (ISSN: 0969-8051, 0883-2897), 1996 Sep; 23(6): 677-680.
Impact Factor: 1.042
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Bonomo RP, Di Blasio B, Maccarrone G, Pavone V, Pedone C, Rizzarelli E, Saviano M, Vecchio G
Crystal and Molecular Structure of the [6-Deoxy-6-[(2-(4-imidazolyl)ethyl)amino]cyclomaltoheptaose]copper(II) Ternary Complex with L-Tryptophanate. Role of Weak Forces in the Chiral Recognition Process Assisted by a Metallocyclodextrin (184 visite)
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 1996 Jul 17; 35(15): 4497-4504.
Impact Factor: 2.736
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Maurea S, Cuocolo A, Reynolds JC, Neumann RD, Salvatore M
Diagnostic imaging in patients with paragangliomas. Computer tomography, magnetic resonance and MIBG scintigraphy comparison (129 visite)
Q J Nucl Med (ISSN: 1124-3937, 1125-0135), 1996; 40(4): 365-371.
Impact Factor: 2.125
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Lastoria S, Maurea S, Vergara E, Acampa W, Varrella P, Klain M, Muto P, Bernardy JD, Salvatore M
Comparison of labeled MIBG and somatostatin analogs in imaging neuroendocrine tumors (135 visite)
Q J Nucl Med (ISSN: 1125-0135, 1124-3937), 1995 Dec; 39(4Suppl1): 145-149.
Impact Factor: 2.125
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Maurea S, Lastoria S, Cuocolo A, Celentano L, Salvatore M
The diagnosis of nonfunctioning pheochromocytoma the role of I-123 MIBG imaging (97 visite)
Clin Nucl Med (ISSN: 0363-9762, 1536-0229, 1536-0229electronic), 1995 Jan; 20(1): 22-24.
Impact Factor: 0.34
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MAUREA S, LASTORIA S, CARACO C, INDOLFI P, CASALE F, DITULLIO M, SALVATORE M
IODINE-131-MIBG IMAGING TO MONITOR CHEMOTHERAPY RESPONSE IN ADVANCED NEUROBLASTOMA - COMPARISON WITH LABORATORY ANALYSIS (158 visite)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1994 Sep; 35(9): 1429-1435.
Impact Factor: 3.491
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Maurea S, Lastoria S, Klain M, Brunetti A, Boscaino A, Lupoli G, Salvatore M
Diagnostic evaluation of thyroid involvement by histiocytosis (109 visite)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1994 Feb; 35(2): 263-265.
Impact Factor: 3.491
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Maurea S, Cuocolo A, Reynolds J, Keiser H, Neumann R, Salvatore M
Iodine-131 metaiodobenzylguanidine scintigraphy in the evaluation of paragangliomas. Comparison between benign and malignant tumors (103 visite)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1994; 87(5): 688-693.
Impact Factor: 0.967
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Lastoria S, Caraco C, Maurea S, Piroli C, Maurelli L, Vergara E, Klain M, Cuocolo A, Salvatore M
Evaluation of orbital involvement by neuroblastoma using radiolabeled metaiodobenzylguanidine (99 visite)
Ital J Ophthalmol (ISSN: 0394-610x), 1993; 7(3): 147-152.
Impact Factor: 0
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Maurea S, Maurelli L, Lastoria S, Cuocolo A, Brunetti A, Pace L, Caracò C, Klain M, Lupoli G, Salvatore M
Familial pheochromocytoma in Sipple's syndrome. A comparison between scintigraphy with 131I-meta-iodobenzylguanidine, computed tomography and echography (122 visite)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1992; 83(4): 486-490.
Impact Factor: 0.967
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Maurelli L, Cuocolo A, Lastoria S, Brunetti A, Maurea S, Lembo G, Klain M, Carac C, Salvatore M
131I-meta-iodobenzylguanidine scintigraphy in patients with a suspected pheochromocytoma. A comparison with CT and biohumoral parameters (123 visite)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 1991; 82(6): 839-843.
Impact Factor: 0.967
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Alberghina M, Brogna A, Mangiameli A, Marletta F, Rizzarelli E, Sammartano S
Copper(II) complexes of aminoacids: Gastric acid antisecretory activity in rats (126 visite)
Farmaco Ed Sci, 1982 Dec; 37(12): 805-814.
Impact Factor: 0
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Marletta F, Rizzarelli E, Mangiameli A, Brogna A, Sammartano S, Monaco S, Blasi A
Effects of graded doses of copper complexes of L-aminoacids on gastric acid secretion in rats (152 visite)
Boll Soc Ital Biol Sper (ISSN: 0037-8771), 1979 Apr 30; 55(8): 769-775.
Impact Factor: 0
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93 Records (89 escludendo Abstract e Conferenze).
Impact factor totale: 309.462 (291.867 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 320.05 (302.242 escludendo Abstract e Conferenze).
Impact factor totale: 309.462 (291.867 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 320.05 (302.242 escludendo Abstract e Conferenze).
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