A virulence factor encoded by a polydnavirus confers tolerance to transgenic tobacco plants against lepidopteran larvae, by impairing nutrient absorption
A virulence factor encoded by a polydnavirus confers tolerance to transgenic tobacco plants against lepidopteran larvae, by impairing nutrient absorption(132 visite) Di Lelio I, Caccia S, Coppola M, Buonanno M, Di Prisco G, Varricchio P, Franzetti E, Corrado G, Monti SM, Rao R, Casartelli M, Pennacchio F
PLOS ONE (ISSN: 1932-6203), 2014 Dec 1; 9(12): N/D-N/D.
Tipo di articolo: Journal Article, Abstract, Conference,
Impact factor: 3.234, Impact factor a 5 anni: 3.702
*** IBB - CNR *** Dipartimento di Agraria, Università di Napoli Federico IIPortici, Italy Istituto di Biostrutture e Bioimmagini (IBB), CNRNapoli, Italy Dipartimento di Scienze e Tecnologie Ambientali, Biologiche e Farmaceutiche, Seconda Università di NapoliCaserta, Italy Dipartimento di Bioscienze, Università degli Studi di MilanoMilano, Italy
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Casida, J. E., Durkin, K. A., Neuroactive insecticides: Targets, selectivity, resistance, and secondary effects (2013) Annu Rev Entomol, 58, pp. 99-117
Horowitz, A. R., Ishaaya, I., (2004) Insect Pest Management, p. 344. , Springer-Verlag, Berlin
Norris, R. F., Caswell-Chen, E. P., Kogan, M., (2003) Concepts in Integrated Pest Management, p. 586. , Prentice Hall, Upper Saddle River, New Jersey
Ehler, L. E., Integrated pest management (IPM): Definition, historical development and implementation, and the other IPM (2006) Pest Manag Sci, 62, pp. 787-789
Brewer, M. J., Goodell, P. B., Approaches and incentives to implement integrated pest management that addresses regional and environmental issues (2012) Annu Rev Entomol, 57, pp. 41-59
Bale, J. S., Van Lenteren, J. C., Bigler, F., Biological control and sustainable food production (2008) Philos T R Soc B, 63, pp. 761-776
Roh, J. Y., Choi, J. Y., Li, M. S., Jin, B. R., Je, Y. H., Bacillus thuringiensis as a specific, safe, and effective tool for insect pest control (2007) J Microbiol Biotechnol, 17, pp. 547-559
Sparks, T. C., Crousel, G. D., Durst, G., Natural products as insecticides: The biology, biochemistry and quantitative structure-activity relationships of spinosyns and spinosoids (2001) Pest Manag Sci, 57, pp. 896-905
Kirst, H. A., The spinosyn family of insecticides: Realizing the potential of natural products research (2010) J Antibiot, 63, pp. 101-111
Smith, J. J., Herzig, V., King, G. F., Alewood, P. F., The insecticidal potential of venom peptides (2013) Cell Mol Life Sci, 70, pp. 3665-3693
Quicke, D. L. J., (1997) Parasitic Wasps, , London: Chapman & Hall
Whitfield, J. B., Phylogenetic insights into the evolution of parasitism in Hymenoptera (2003) Adv Parasitol, 54, pp. 69-100
Kroemer, J. A., Webb, B. A., Polydnavirus genes and genomes: Emerging gene families and new insights into polydnavirus replication (2004) Annu Rev Entomol, 49, pp. 431-456
Webb, B. A., Strand, M. R., The Biology and Genomics of Polydnaviruses (2005) Comprehensive Molecular Insect Science, 6, pp. 323-360. , (L. I. Gilbert, K. Iatrou, S. S. Gill, Eds). Elsevier, San Diego
Strand, M. R., Polydnavirus gene products that interact with the host immune system (2012) Parasitoid Viruses: Symbionts and Pathogens, pp. 149-161. , Edited by BeckageNE, DrezenJ-M. Elsevier
Maiti, I. B., Dey, N., Dahlman, D. L., Webb, B. A., Antibiosis-type resistance in transgenic plants expressing teratocyte secretory peptide (TSP) gene from hymenopteran endoparasite (Microplitis croceipes) (2003) Plant Biotechnol, 1, pp. 209-219
Gill, T. A., Fath-Goodin, A., Maiti, I. B., Webb, B. A., Potential uses of cys-motif and other polydnavirus genes in biotechnology (2006) Adv Virus Res, 68, pp. 393-426
Danna, K. J., Production of cellulases in plants for biomass conversion (2001) Regulation of Phytochemicals by Molecular Techniques, pp. 206-223. , Eds, JA Saunders, , BF Matthews
Fulton, T. M., Chunwongse, J., Tanksley, S. D., Microprep protocol for extraction of DNA from tomato and other herbaceous plants (1995) Plant Mol Biol Rep, 13, pp. 207-209
Shewmaker, C. K., Ridge, N. P., Pokalsky, A. R., Rose, R. E., Hiatt, W. R., Nucleotide sequence of an EF-1 alpha genomic clone from tomato (1190) Nucleic Acids Res, 14, p. 4276
Bradford, M. M., A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding (1976) Anal Biochem, 72, pp. 248-254
Schmitz, K. S., (1990) Dynamic Light Scattering by Macromolecules, , Academic Press, Boston
Leonardi, M. G., Casartelli, M., Parenti, P., Giordana, B., Evidence for a low-affinity, high-capacity uniport for amino acids in Bombyx mori larval midgut (1998) Am J Physiol, 274, pp. R1372-R1375
Leonardi, M. G., Caccia, S., Gonzalez-Cabrera, J., Ferr, J., Giordana, B., Leucine transport is affected by Bacillus thuringiensis Cry1 toxins in brush border membrane vesicles from Ostrinia nubilalis Hb (Lepidoptera: Pyralidae) and Sesamia nonagrioides Lefebvre (Lepidoptera: Noctuidae) midgut (2007) J Membrane Biol, 214, pp. 157-164
Li, H. M., Sun, L., Mittapalli, O., Muir, W. M., Xie, J., Transcriptional signatures in response to wheat germ agglutinin and starvation in Drosophila melanogaster larval midgut (2009) Insect Mol Biol, 18, pp. 21-31
The biological control of insect pests is based on the use of natural enemies. However, the growing information on the molecular mechanisms underpinning the interactions between insects and their natural antagonists can be exploited to develop "bio-inspired" pest control strategies, mimicking suppression mechanisms shaped by long co-evolutionary processes. Here we focus on a virulence factor encoded by the polydnavirus associated with the braconid wasp Toxoneuron nigriceps (TnBV), an endophagous parasitoid of noctuid moth larvae. This virulence factor (TnBVANK1) is a member of the viral ankyrin (ANK) protein family, and appears to be involved both in immunosuppression and endocrine alterations of the host. Transgenic tobacco plants expressing TnBVANK1 showed insecticide activity and caused developmental delay in Spodoptera littoralis larvae feeding on them. This effect was more evident in a transgenic line showing a higher number of transcripts of the viral gene. However, this effect was not associated with evidence of translocation into the haemocoel of the entire protein, where the receptors of TnBVANK1 are putatively located. Indeed, immunolocalization experiments evidenced the accumulation of this viral protein in the midgut, where it formed a thick layer coating the brush border of epithelial cells. In vitro transport experiments demonstrated that the presence of recombinant TnBVANK1 exerted a dose- dependent negative impact on amino acid transport. These results open new perspectives for insect control and stimulate additional research efforts to pursue the development of novel bioinsecticides, encoded by parasitoid-derived genes. However, future work will have to carefully evaluate any effect that these molecules may have on beneficial insects and on non-target organisms.
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