Is avolition in schizophrenia associated with a deficit of dorsal caudate activity? A functional magnetic resonance imaging study during reward anticipation and feedback
CNR Ibb | back to homepage
▲NavBar
Ricerca avanzata▼
Contiene: [X]      Estesa     Autori: [X]  Tipo di lavoro: [X]   Data iniziale: Data finale: [X]      Sede: Affiliazione IBB     
    
[Pulisci modulo]


Is avolition in schizophrenia associated with a deficit of dorsal caudate activity? A functional magnetic resonance imaging study during reward anticipation and feedback (117 visite)

Mucci A, Dima D, Soricelli A, Volpe U, Bucci P, Frangou S, Prinster A, Salvatore M, Galderisi S, Maj M

PSYCHOL MED (ISSN: 0033-2917), 2015 Jan 12; 45(8): 1765-1778.



Tipo di articolo: Journal Article,

Impact factor: 5.491, Impact factor a 5 anni: 5.969

Url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84988258835&doi=10.1017%2fS0033291714002943&partnerID=40&md5=88fcadffbf1b15b682071af5b065f619

Parole chiave: Avolition, Deficit Schizophrenia, Dorsal Caudate, Reward Anticipation, Ventral Striatum, Adaptive Behavior, Adult, Brain, Brain Mapping, Female, Human, Motivation, Nuclear Magnetic Resonance Imaging, Pathophysiology, Psychological, Feedback,

Affiliazioni:

*** IBB - CNR ***
Department of Psychiatry,University of Naples SUN,Naples,Italy.
Psychosis Research Program,Department of Psychiatry,Icahn School of Medicine at Mount SinaiNew York,USA.
Biostructure and Bioimaging Institute,National Research Council,Naples,Italy.
Department of Biomorphological and Functional Studies,University of Naples 'Federico II',Naples,Italy.
MRC Social Genetic and Developmental Psychiatry, Institute of Psychiatry, King's College London, United Kingdom


Riferimenti:

Abler, B., Greenhouse, I., Ongur, D., Walter, H., Heckers, S., Abnormal reward system activation in mania (2008) Neuropsychopharmacology, 33, pp. 2217-222

Balleine, B.W., Delgado, M.R., Hikosaka, O., The role of the dorsal striatum in reward and decision-making (2007) Journal of Neuroscience, 27, pp. 8161-8165

Balleine, B.W., O'doherty, J.P., Human and rodent homologies in action control: Corticostriatal determinants of goal-directed and habitual action (2010) Neuropsychopharmacology, 35, pp. 48-69

Barch, D.M., Dowd, E.C., Goal representations and motivational drive in schizophrenia: The role of prefrontal-striatal interactions (2010) Schizophrenia Bulletin, 36, pp. 919-934

Berridge, K.C., Robinson, T.E., Parsing reward (2003) Trends in Neurosciences, 26, pp. 507-513

Cohen, A.S., Minor, K.S., Emotional experience in patients with schizophrenia revisited: Meta-Analysis of laboratory studies (2010) Schizophrenia Bulletin, 36, pp. 143-150

Chapman, L.J., Chapman, J.P., (1978) Revised Physical Anhedonia Scale, , Available from L. J. Chapman, Department of Psychology, 1202 West Johnson Street, University of Wisconsin, Madison, WI 53706

Delgado, M.R., Miller, M.M., Inati, S., Phelps, E.A., An fmri study of reward-related probability learning (2005) Neuroimage, 24, pp. 862-873

Delgado, M.R., Nystrom, L.E., Fissell, C., Noll, D.C., Fiez, J.A., Tracking the hemodynamic responses to reward and punishment in the striatum (2000) Journal of Neurophysiology, 84, pp. 3072-3077

Delgado, M.R., Stenger, V.A., Fiez, J.A., Motivation-dependent responses in the human caudate nucleus (2004) Cerebral Cortex, 14, pp. 1022-1030

De Quervain, D.J., Fischbacher, U., Treyer, V., Schellhammer, M., Schnyder, U., Buck, A., Fehr, E., The neural basis of altruistic punishment (2004) Science, 27, pp. 1254-1258

Der-Avakian, A., Markou, A., The neurobiology of anhedonia and other reward-related deficits (2012) Trends in Neurosciences, 35, pp. 68-77

Dolan, R.J., Dayan, P., Goals and habits in the brain (2013) Neuron, 80, pp. 312-325

Ehrlich, S., Yendiki, A., Greve, D.N., Manoach, D.S., Ho, B.C., White, T., Schulz, S.C., Holt, D.J., Striatal function in relation to negative symptoms in schizophrenia (2012) Psychological Medicine, 42, pp. 267-282

Elliott, R., Friston, K.J., Dolan, R.J., Dissociable neural responses in human reward systems (2000) Journal of Neuroscience, 20, pp. 6159-6165

Esslinger, C., Englisch, S., Inta, D., Rausch, F., Schirmbeck, F., Mier, D., Kirsch, P., Zink, M., Ventral striatal activation during attribution of stimulus saliency and reward anticipation is correlated in unmedicated first episode schizophrenia patients (2012) Schizophrenia Research, 140, pp. 114-121

Foussias, G., Mann, S., Zakzanis, K.K., Van Reekum, R., Remington, G., Motivational deficits as the central link to functioning in schizophrenia: A pilot study (2009) Schizophrenia Research, 115, pp. 333-337

Foussias, G., Remington, G., Negative symptoms in schizophrenia: Avolition and occam's razor (2010) Schizophrenia Bulletin, 36, pp. 359-369

Galderisi, S., Bucci, P., Mucci, A., Kirkpatrick, B., Pini, S., Rossi, A., Vita, A., Maj, M., Categorical and dimensional approaches to negative symptoms of schizophrenia: Focus on long-Term stability and functional outcome (2013) Schizophrenia Research, 147, pp. 157-162

Gard, D.E., Gard, M.G., Kring, A.M., John, O.P., Anticipatory and consummatory components of the experience of pleasure: A scale development study (2006) Journal of Research in Personality, 40, pp. 1086-1102

Gard, D.E., Kring, A.M., Gard, M.G., Horan, W.P., Green, M.F., Anhedonia in schizophrenia: Distinctions between anticipatory and consummatory pleasure (2007) Schizophrenia Research, 93, pp. 253-260

Gardner, D.M., Murphy, A.L., O'donnell, H., Centorrino, F., Baldessarini, R.J., International consensus study of antipsychotic dosing (2010) American Journal of Psychiatry, 167, pp. 686-693

Goghari, V.M., Sponheim, S.R., MacDonald, A.W., III, The functional neuroanatomy of symptom dimensions in schizophrenia: A qualitative and quantitative review of a persistent question (2010) Neuroscience Biobehavioral Review, 34, pp. 468-486

Grahn, J.A., Parkinson, J.A., Owen, A.M., The cognitive functions of the caudate nucleus (2008) Progress in Neurobiology, 86, pp. 141-155

Haber, S.N., Knutson, B., The reward circuit: Linking primate anatomy and human imaging (2010) Neuropsychopharmacology, 35, pp. 4-26

Haruno, M., Kawato, M., Different neural correlates of reward expectation and reward expectation error in the putamen and caudate nucleus during stimulus-Actionreward association learning (2006) Journal of Neurophysiology, 95, pp. 948-959

Heerey, E.A., Gold, J.M., Patients with schizophrenia demonstrate dissociation between affective experience and motivated behavior (2007) Journal of Abnormal Psychology, 116, pp. 268-278

Heerey, E.A., Robinson, B.M., McMahon, R.P., Gold, J.M., Delay discounting in schizophrenia (2007) Cognitive Neuropsychiatry, 12, pp. 213-221

Heinrichs, D.W., Hanlon, T.E., Carpenter, W.T., Jr., The quality of life scale: An instrument for rating the schizophrenic deficit syndrome (1984) Schizophrenia Bulletin, 10, pp. 388-398

Juckel, G., Schlagenhauf, F., Koslowski, M., Filonov, D., Wüstenberg, T., Villringer, A., Knutson, B., Heinz, A., Dysfunction of ventral striatal reward prediction in schizophrenic patients treated with typical, not atypical, neuroleptics (2006) Psychopharmacology, 187, pp. 222-228

Kay, S.R., Fiszbein, A., Opler, L.A., The positive and negative syndrome scale (panss) for schizophrenia (1987) Schizophrenia Bulletin, 13, pp. 261-276

Kimhy, D., Yale, S., Goetz, R.R., McFarr, L.M., Malaspina, D., The factorial structure of the schedule for the deficit syndrome in schizophrenia (2006) Schizophrenia Bulletin, 32, pp. 274-278

King-Casas, B., Tomlin, D., Anen, C., Camerer, C.F., Quartz, S.R., Montague, P.R., Getting to know you: Reputation and trust in a two-person economic exchange (2005) Science, 308, pp. 78-83

Kirkpatrick, B., Buchanan, R.W., McKenney, P.D., Alphs, L.D., Carpenter, W.T., Jr., The schedule for the deficit syndrome: An instrument for research in schizophrenia (1989) Psychiatry Research, 30, pp. 119-123

Kirkpatrick, B., Fenton, W.S., Carpenter, W.T., Jr., Marder, S.R., The nimh-matrics consensus statement on negative symptoms (2006) Schizophrenia Bulletin, 32, pp. 214-219

Knutson, B., Adams, C.M., Fong, G.W., Hommer, D., Anticipation of increasing monetary reward selectively recruits nucleus accumbens (2001) Journal of Neuroscience, 21, p. RC159

Knutson, B., Fong, G.W., Adams, C.M., Varner, J.L., Hommer, D., Dissociation of reward anticipation and outcome with event-related fmri (2001) Neuroreport, 12, pp. 3683-3687

Knutson, B., Westdorp, A., Kaiser, E., Hommer, D., Fmri visualization of brain activity during a monetary incentive delay task (2000) Neuroimage, 12, pp. 20-27

Kring, A.M., Moran, E.K., Emotional response deficits in schizophrenia: Insights from affective science (2008) Schizophrenia Bulletin, 34, pp. 819-834

Manes, F., Sahakian, B., Clark, L., Antoun, N., Aitken, M., Robbins, T., Decision-making processes following damage to the prefrontal cortex (2002) Brain, 125, pp. 624-639

Mann, C.L., Footer, O., Chung, Y.S., Driscoll, L.L., Barch, D.M., Spared and impaired aspects of motivated cognitive control in schizophrenia (2013) Journal of Abnormal Psychology, 122, pp. 745-755

Miller, E.K., Cohen, J.D., An integrative theory of prefrontal cortex function (2001) Annual Review of Neuroscience, 21, pp. 167-202

Miller, E.M., Shankar, M.U., Knutson, B., McClure, S.M., Dissociating motivation from reward in human striatal activity (2014) Journal of Cognitive Neuroscience, 26, pp. 1075-1084

Nakagami, E., Hoe, M., Brekke, J.S., The prospective relationships among intrinsic motivation, neurocognition, and psychosocial functioning in schizophrenia (2010) Schizophrenia Bulletin, 36, pp. 935-948

Nielsen, M., Rostrup, E., Wulff, S., Bak, N., Broberg, B.V., Lublin, H., Kapur, S., Glenthoh

j, B., Improvement of brain reward abnormalities by antipsychotic monotherapy in schizophrenia (2012) Archives of General Psychiatry, 69, pp. 1195-1204

j, B., Alterations of the brain reward system in antipsychotic na've schizophrenia patients (2012) Biological Psychiatry, 71, pp. 898-905

O'donnell, P., Grace, A.A., Synaptic interactions among excitatory afferents to nucleus accumbens neurons: Hippocampal gating of prefrontal cortical input (1995) Journal of Neuroscience, 15, pp. 3622-3639

Palmiter, R.D., Dopamine signaling in the dorsal striatum is essential for motivated behaviors: Lessons from dopamine-deficient mice (2008) Annals of the New York Academy of Sciences, 1129, pp. 35-46

Peters, J., Büchel, C., Neural representations of subjective reward value (2010) Behavioural Brain Research, 213, pp. 135-141

Rilling, J., Gutman, D., Zeh, T., Pagnoni, G., Berns, G., Kilts, C., A neural basis for social cooperation (2002) Neuron, 18, pp. 395-405

Robinson, J.L., Laird, A.R., Glahn, D.C., Blangero, J., Sanghera, M.K., Pessoa, L., Fox, P.M., Fox, P.T., The functional connectivity of the human caudate: An application of meta-Analytic connectivity modeling with behavioral filtering (2012) Neuroimage, 60, pp. 117-129

Schlagenhauf, F., Juckel, G., Koslowski, M., Kahnt, T., Knutson, B., Dembler, T., Kienast, T., Heinz, A., Reward system activation in schizophrenic patients switched from typical neuroleptics to olanzapine (2008) Psychopharmacology, 196, pp. 673-684

Schlagenhauf, F., Sterzer, P., Schmack, K., Ballmaier, M., Rapp, M., Wrase, J., Juckel, G., Heinz, A., Reward feedback alterations in unmedicated schizophrenia patients: Relevance for delusions (2009) Biological Psychiatry, 65, pp. 1032-1039

Sescousse, G., Redouté, J., Dreher, J.C., The architecture of reward value coding in the human orbitofrontal cortex (2010) Journal of Neuroscience, 30, pp. 13095-13104

Sheehan, D.V., Lecrubier, Y., Sheehan, K.H., Amorim, P., Janavs, J., Weiller, E., Hergueta, T., Dunbar, G.C., The mini-international neuropsychiatric interview (mini): The development and validation of a structured diagnostic psychiatric interview for dsm-iv and icd-10 (1998) Journal of Clinical Psychiatry, 59, pp. 22-33

Simon, J.J., Biller, A., Walther, S., Roesch-Ely, D., Stippich, C., Weisbrod, M., Kaiser, S., Neural correlates of reward processing in schizophrenia: Relationship to apathy and depression (2010) Schizophrenia Research, 118, pp. 154-161

Simpson, E.H., Waltz, J.A., Kellendonk, C., Balsam, P.D., Schizophrenia in translation: Dissecting motivation in schizophrenia and rodents (2012) Schizophrenia Bulletin, 38, pp. 1111-1117

Strauss, G.P., Horan, W.P., Kirkpatrick, B., Fischer, B.A., Keller, W.R., Miski, P., Buchanan, R.W., Carpenter, W.T., Jr., Deconstructing negative symptoms of schizophrenia: Avolition-Apathy and diminished expression clusters predict clinical presentation and functional outcome (2013) Journal of Psychiatric Research, 47, pp. 783-790

Strauss, G.P., Waltz, J.A., Gold, J.M., (2013) A Review of Reward Processing and Motivational Impairment in Schizophrenia, , Schizophrenia Bulletin. Published online: 22 February 2014

Tricomi, E.M., Delgado, M.R., Fiez, J.A., Modulation of caudate activity by action contingency (2004) Neuron, 41, pp. 281-292

Volpe, U., Mucci, A., Quarantelli, M., Galderisi, S., Maj, M., Dorsolateral prefrontal cortex volume in patients with deficit or nondeficit schizophrenia (2012) Progress in Neuro-psychopharmacology and Biological Psychiatry, 37, pp. 264-269

Walter, H., Kammerer, H., Frasch, K., Spitzer, M., Abler, B., Altered reward functions in patients on atypical antipsychotic medication in line with the revised dopamine hypothesis of schizophrenia (2009) Psychopharmacology, 206, pp. 121-132

Waltz, J.A., Frank, M.J., Robinson, B.M., Gold, J.M., Selective reinforcement learning deficits in schizophrenia support predictions from computational models of striatal-cortical dysfunction (2007) Biological Psychiatry, 62, pp. 756-764

Waltz, J.A., Schweitzer, J.B., Ross, T.J., Kurup, P.K., Salmeron, B.J., Rose, E.J., Gold, J.M., Stein, E.A., Abnormal responses to monetary outcomes in cortex, but not in the basal ganglia, in schizophrenia (2010) Neuropsychopharmacology, 35, pp. 2427-2439

Wallis, J.D., Orbitofrontal cortex and its contribution to decision-making (2007) Annual Review of Neuroscience, 30, pp. 31-56

Wang, A.Y., Miura, K., Uchida, N., The dorsomedial striatum encodes net expected return, critical for energizing performance vigor (2013) Nature Reviews Neuroscience, 16, pp. 639-647

Yin, H.H., Knowlton, B.J., The role of the basal ganglia in habit formation (2006) Nature Reviews Neuroscience, 7, pp. 464-476



Background The neurobiological underpinnings of avolition in schizophrenia remain unclear. Most brain imaging research has focused on reward prediction deficit and on ventral striatum dysfunction, but findings are not consistent. In the light of accumulating evidence that both ventral striatum and dorsal caudate play a key role in motivation, we investigated ventral striatum and dorsal caudate activation during processing of reward or loss in patients with schizophrenia. Method We used functional magnetic resonance imaging to study brain activation during a Monetary Incentive Delay task in patients with schizophrenia, treated with second-generation antipsychotics only, and in healthy controls (HC). We also assessed the relationships of ventral striatum and dorsal caudate activation with measures of hedonic experience and motivation. Results The whole patient group had lower motivation but comparable hedonic experience and striatal activation than HC. Patients with high avolition scores showed lower dorsal caudate activation than both HC and patients with low avolition scores. A lower dorsal caudate activation was also observed in patients with deficit schizophrenia compared to HC and patients with non-deficit schizophrenia. Dorsal caudate activity during reward anticipation was significantly associated with avolition, but not with anhedonia in the patient group. Conclusions These findings suggest that avolition in schizophrenia is linked to dorsal caudate hypoactivation. © Cambridge University Press 2015.
Nessun risultato.

Ricerca avanzata▼
Contiene: [X]      Estesa     Autori: [X]  Tipo di lavoro: [X]   Data iniziale: Data finale: [X]      Sede: Affiliazione IBB     
    
[Pulisci modulo]
Vai a fine pagina   Versione per copia e incolla facile   Esporta tutto in BibTeX   Esporta tutto in EndNote


Giordano GM, Stanziano M, Papa M, Mucci A, Prinster A, Soricelli A, Galderisi S
* Functional connectivity of the ventral tegmental area and avolition in subjects with schizophrenia: a resting state functional MRI study (56 visite)
European Neuropsychopharmacology (ISSN: 0924-977x), 2018 Apr; 28(5): 589-602.
Impact Factor: 4.239
Dettagli    Esporta in BibTeX    Esporta in EndNote

Amodio A, Quarantelli M, Mucci A, Prinster A, Soricelli A, Vignapiano A, Giordano GM, Merlotti E, Nicita A, Galderisi S
* Avolition-Apathy and White Matter Connectivity in Schizophrenia: Reduced Fractional Anisotropy Between Amygdala and Insular Cortex (53 visite)
Clin Eeg Neurosci (ISSN: 2169-5202electronic, 1550-0594linking), 2018 Jan; 49(1): 55-65.
Impact Factor: 2.163
Dettagli    Esporta in BibTeX    Esporta in EndNote

Sarappa C, Salvatore E, Filla A, Cocozza S, Russo CV, Sacca F, Brunetti A, De Michele G, Quarantelli M
* Functional MRI signal fluctuations highlight altered resting brain activity in Huntington's disease (95 visite)
BRAIN IMAGING BEHAV (ISSN: 1931-7557), 2017 Oct; 11(5): 1459-1469.
Impact Factor: 3.719
Dettagli    Esporta in BibTeX    Esporta in EndNote

Cocozza S, Pisani A, Olivo G, Saccà F, Ugga L, Riccio E, Migliaccio S, Brescia Morra V, Brunetti A, Quarantelli M, Tedeschi E
* Alterations of functional connectivity of the motor cortex in Fabry disease: An RS-fMRI study (3 visite)
NEUROLOGY (ISSN: 0028-3878), 2017; 88(19): 1822-1829.
Impact Factor: 8.055
Dettagli    Esporta in BibTeX    Esporta in EndNote

Longarzo M, Quarantelli M, Aiello M, Romano M, Del Prete A, Cimminiello C, Cocozza S, Olivo G, Loguercio C, Trojano L, Grossi D
* The influence of interoceptive awareness on functional connectivity in patients with irritable bowel syndrome (110 visite)
BRAIN IMAGING BEHAV (ISSN: 1931-7557), 2016 Oct 4; 11(4): 1117-1128.
Impact Factor: 3.985
Dettagli    Esporta in BibTeX    Esporta in EndNote

Palma G, Tedeschi E, Borrelli P, Cocozza S, Russo C, Liu S, Ye Y, Comerci M, Alfano B, Salvatore M, Haacke EM, Mancini M
* A Novel Multiparametric Approach to 3D Quantitative MRI of the Brain (286 visite) (PDF 171 visite)
PLOS ONE (ISSN: 1932-6203), 2015 Aug 18; 10(8): e0134963-e0134963.
Impact Factor: 3.057
Dettagli    Esporta in BibTeX    Esporta in EndNote

Perani D, Della Rosa PA, Cerami C, Gallivanone F, Fallanca F, Vanoli EG, Panzacchi A, Nobili F, Pappata S, Marcone A, Garibotto V, Castiglioni I, Magnani G, Cappa SF, Gianolli L; EADC-PET Consortium
* Validation of an optimized SPM procedure for FDG-PET in dementia diagnosis in a clinical setting (130 visite)
NEUROIMAGE-CLIN (ISSN: 2213-1582), 2014 Oct 24; 6: 445-454.
Impact Factor: 2.526
Dettagli    Esporta in BibTeX    Esporta in EndNote

Borrelli P, Palma G, Tedeschi E, Cocozza S, Russo C, Comerci M, Alfano B, Haacke EM, Salvatore M
* Improving SNR in Susceptibility Weighted Imaging by a NLM-based denoising scheme (207 visite) (PDF 150 visite)
2014 Ieee Int Conf Imaging Syst Tech Proc (ISSN: 9781-479967483), 2014 Oct; 10.1109/IST.2014: 346-350.
Impact Factor: 0
Dettagli    Esporta in BibTeX    Esporta in EndNote

Conson M, Cella L, Pacelli R, Comerci M, Liuzzi R, Salvatore M, Quarantelli M
* Automated delineation of brain structures in patients undergoing radiotherapy for primary brain tumors: From atlas to dose-volume histograms (457 visite) (PDF 284 visite)
RADIOTHER ONCOL (ISSN: 0167-8140), 2014 Sep; 112(3): 326-331.
Impact Factor: 4.363
Dettagli    Esporta in BibTeX    Esporta in EndNote

Grossi D, Grossi D, Soricelli A, Ponari M, Salvatore E, Quarantelli M, Prinster A, Trojano L
* Structural Connectivity In A Single Case Of Progressive Prosopagnosia: The Role Of The Right Inferior Longitudinal Fasciculus (132 visite)
CORTEX (ISSN: 0010-9452), 2014 Jul; 56: 111-120.
Impact Factor: 5.128
Dettagli    Esporta in BibTeX    Esporta in EndNote

Volpe U, Mucci A, Plescia GM, Montefusco V, Romano P, Dima D, Gallo O, Soricelli A, Bucci P, Frangou S, Prinster A, Salvatore M, Maj M, Galderisi S
* REWARD ANTICIPATION IN SCHIZOPHRENIA: A FUNCTIONAL MAGNETIC RESONANCE IMAGING STUDY (117 visite)
EUR PSYCHIAT (ISSN: 0924-9338), 2014; 29: N/D-N/D.
Impact Factor: 3.439
Dettagli    Esporta in BibTeX    Esporta in EndNote

Quarantelli M, Salvatore E, Giorgio SM, Filla A, Cervo A, Russo CV, Cocozza S, Massarelli M, Brunetti A, De Michele G
* Default-mode network changes in Huntington's disease: an integrated MRI study of functional connectivity and morphometry (118 visite)
Plosone (ISSN: 1932-6203, 1932-6203electronic), 2013 Sep 19; 8(8): e72159-e72159.
Impact Factor: 3.534
Dettagli    Esporta in BibTeX    Esporta in EndNote

Volpe U, Mucci A, Quarantelli M, Galderisi S, Maj M
* Dorsolateral prefrontal cortex volume in patients with deficit or nondeficit schizophrenia (115 visite) (PDF 113 visite)
Prog Neuro Psychopharmacol Biol Psychiatry (ISSN: 0278-5846), 2012 Jun 1; 37(2): 264-269.
Impact Factor: 3.552
Dettagli    Esporta in BibTeX    Esporta in EndNote

Pappata S, Santangelo G, Aarsland D, Vicidomini C, Longo K, Bronnick K, Amboni M, Erro R, Vitale C, Caprio MG, Pellecchia MT, Brunetti A, De Michele G, Salvatore M, Barone P
* Mild cognitive impairment in drug-naive patients with PD is associated with cerebral hypometabolism (146 visite)
Neurology (ISSN: 0028-3878, 1526-632x, 1526-632xelectronic), 2011 Oct 4; 77(14): 1357-1362.
Impact Factor: 8.312
Dettagli    Esporta in BibTeX    Esporta in EndNote

Esmaeilzadeh M, Farde L, Karlsson P, Varrone A, Halldin C, Waters S, Tedroff J
* Extrastriatal dopamine D 2 receptor binding in Huntington's disease (173 visite)
Hum Brain Mapp (ISSN: 1065-9471, 1097-0193electronic, 1065-9471linking), 2011 Oct; 32(10): 1626-1636.
Impact Factor: 5.88
Dettagli    Esporta in BibTeX    Esporta in EndNote

Prinster A, Quarantelli M, Lanzillo R, Orefice G, Vacca G, Carotenuto B, Alfano B, Brunetti A, Brescia Morra V, Salvatore M
* A voxel-based morphometry study of disease severity correlates in relapsing- remitting multiple sclerosis (143 visite) (PDF 114 visite)
Mult Scler (ISSN: 1352-4585, 1477-0970, 1352-4585linking), 2010 Jan; 16(1): 45-54.
Impact Factor: 4.23
Dettagli    Esporta in BibTeX    Esporta in EndNote

Pellecchia MT, Barone PB, Mollica C, Salvatore E, Ianniciello M, Longo K, Varrone A, Vicidomini C, Picillo M, De Michele G, Filla A, Salvatore M, Pappata S
* Diffusion-weighted imaging in multiple system atrophy: a comparison between clinical subtypes (166 visite)
Mov Disord (ISSN: 1531-8257, 0885-3185), 2009 Apr 15; 24(5): 689-696.
Impact Factor: 4.014
Dettagli    Esporta in BibTeX    Esporta in EndNote

Mcnab F, Varrone A, Farde L, Jucaite A, Bystritsky P, Forssberg H, Klingberg T
* Changes in cortical dopamine D1 receptor binding associated with cognitive training (150 visite)
Science (ISSN: 0036-8075), 2009 Feb 6; 323(5915): 800-802.
Impact Factor: 29.747
Dettagli    Esporta in BibTeX    Esporta in EndNote

Takano A, Varrone A, Gulyas B, Karlsson P, Tauscher J, Halldin C
* Mapping of the norepinephrine transporter in man using PET with (S, S)-[F-18]FMeNER-D-2 (103 visite) (PDF 136 visite)
Neuroimage (ISSN: 1053-8119, 1053-8119linking), 2008 Sep 15; 41: 474-482.
Impact Factor: 5.694
Dettagli    Esporta in BibTeX    Esporta in EndNote

Morra VB, Prinster A, Lanzillo R, Quarantelli M, Vacca G, Mollica C, Schiavone V, Brunetti A, Salvatore E, Alfano B, Orefice G
* Correlation of disease severity and regional brain tissue loss in relapsing-remitting multiple sclerosis: a voxel-based morphometry study in a large population (146 visite) (PDF 114 visite)
Mult Scler (ISSN: 1352-4585, 1477-0970, 1352-4585linking), 2008 Sep; 14: 45-54.
Impact Factor: 3.312
Dettagli    Esporta in BibTeX    Esporta in EndNote

Galderisi S, Quarantelli M, Volpe U, Mucci A, Cassano GB, Invernizzi G, Rossi A, Vita A, Pini S, Cassano P, Daneluzzo E, De Peri L, Stratta P, Brunetti A, Maj M
* Patterns of structural MRI abnormalities in deficit and nondeficit schizophrenia (258 visite) (PDF 111 visite)
Schizophr Bull (ISSN: 0586-7614), 2008 Mar; 34(2): 393-401.
Impact Factor: 6.592
Dettagli    Esporta in BibTeX    Esporta in EndNote

Tedeschi G, Dinacci D, Lavorgna L, Prinster A, Savettieri G, Quattrone A, Livrea P, Messina C, Reggio A, Servillo G, Bresciamorra V, Orefice G, Paciello M, Brunetti A, Paolillo A, Coniglio G, Bonavita S, Di Costanzo A, Bellacosa A, Valentino P, Quarantelli M, Patti F, Salemi G, Cammarata E, Simone I, Salvatore M, Bonavita V, Alfano B
* Correlation between fatigue and brain atrophy and lesion load in multiple sclerosis patients independent of disability (176 visite) (PDF 133 visite)
J Neurol Sci (ISSN: 0022-510x), 2007 Dec 15; 263(1-2): 15-19.
Impact Factor: 2.315
Dettagli    Esporta in BibTeX    Esporta in EndNote

Varrone A, Pagani M, Salvatore E, Salmaso D, Sansone V, Amboni M, Nobili F, De Michele G, Filla A, Barone P, Pappata S, Salvatore M
* Identification by [Tc-99]ECD SPECT of anterior cingulate hypoperfusion in progressive supranuclear palsy, in comparison with Parkinson's disease (163 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2007 Jul; 34(7): 1071-1081.
Impact Factor: 4.101
Dettagli    Esporta in BibTeX    Esporta in EndNote

Landmann C, Dehaene S, Pappata S, Jobert A, Bottlaender M, Roumenov D, Le Bihan D
* Dynamics of prefrontal and cingulate activity during a reward-based logical deduction task (135 visite)
Cereb Cortex (ISSN: 1047-3211), 2007 Apr; 17(4): 749-759.
Impact Factor: 6.519
Dettagli    Esporta in BibTeX    Esporta in EndNote

Berkouk K, Quarantelli M, Prinster A, Landeau B, Alfano B, Baron JC
* Mapping The Relative Contribution Of Gray Matter Activity Versus Volume In Brain Pet. A New Approach (166 visite) (PDF 137 visite)
J Neuroimaging (ISSN: 1051-2284), 2006 Jul; 16(3): 224-235.
Impact Factor: 1.298
Dettagli    Esporta in BibTeX    Esporta in EndNote

Tedeschi G, Lavorgna L, Russo P, Prinster A, Dinacci D, Savettieri G, Quattrone A, Livrea P, Messina C, Reggio A, Bresciamorra V, Orefice G, Paciello M, Brunetti A, Coniglio G, Bonavita S, Di Costanzo A, Bellacosa A, Valentino P, Quarantelli M, Patti F, Salemi G, Cammarata E, Simone IL, Salvatore M, Bonavita V, Alfano B
* Brain atrophy and lesion load in a large population of patients with multiple sclerosis (174 visite) (PDF 159 visite)
Neurology (ISSN: 0028-3878, 1526-632x, 1526-632xelectronic), 2005 Jul 26; 65(2): 280-285.
Impact Factor: 5.065
Dettagli    Esporta in BibTeX    Esporta in EndNote

Buffon F, Molko N, Hervé D, Porcher R, Denghien I, Pappata S, Le Bihan D, Bousser MG, Chabriat H
* Longitudinal diffusion changes in cerebral hemispheres after MCA infarcts (91 visite)
J Cereb Blood Flow Metab (ISSN: 0271-678x, 0271-678xlinking), 2005 May; 25(5): 641-650.
Impact Factor: 4.786
Dettagli    Esporta in BibTeX    Esporta in EndNote

Galderisi S, Mucci A, Quarantelli M, Volpe U, Amati G, Alfano B, Maj M
* Structural and functional brain imaging findings in deficit and nondeficit schizophrenia (98 visite)
International Journal Of Neuropsychopharmacology (ISSN: 1461-1457), 2004 Jun; 7: N/D-N/D.
Impact Factor: 4.128
Dettagli    Esporta in BibTeX    Esporta in EndNote

Galderisi S, Del Zompo M, Invernizzi G, Pini S, Quarantelli M, Rossi A, Cassano P, Severino G, Stratta P, Vita A, Volpe U, Salvatore M, Maj M
* MRI, neuropsychological and genetic findings in deficit and non-deficit schizophrenia: A multicentre study (82 visite)
European Psychiatry (ISSN: 0924-9338), 2004 Apr; 19: N/D-N/D.
Impact Factor: 1.191
Dettagli    Esporta in BibTeX    Esporta in EndNote

Amato U, Larobina M, Antoniadis A, Alfano B
* Segmentation of magnetic resonance brain images through discriminant analysis (261 visite) (PDF 141 visite)
J Neurosci Methods (ISSN: 0165-0270, 0165-0270linking, 1872-678xelectronic), 2003 Dec 30; 131(1-2): 65-74.
Impact Factor: 1.777
Dettagli    Esporta in BibTeX    Esporta in EndNote

Quarantelli M, Ciarmiello A, Morra VB, Orefice G, Larobina M, Lanzillo R, Schiavone V, Salvatore E, Alfano B, Brunetti A
* Brain tissue volume changes in relapsing-remitting multiple sclerosis: Correlation with lesion load (185 visite) (PDF 133 visite)
Neuroimage (ISSN: 1053-8119, 1053-8119linking), 2003 Feb; 18(2): 360-366.
Impact Factor: 6.192
Dettagli    Esporta in BibTeX    Esporta in EndNote

Pappata S, Dehaene S, Poline JB, Gregoire MC, Jobert A, Delforge J, Frouin V, Bottlaender M, Dolle F, Di Giamberardino L, Syrota A
* In Vivo detection of striatal dopamine release during reward: A PET study with [11C]raclopride and a single dynamic scan approach (136 visite)
Neuroimage (ISSN: 1053-8119, 1053-8119linking), 2002 Sep; 16(4): 1015-1027.
Impact Factor: 5.624
Dettagli    Esporta in BibTeX    Esporta in EndNote

Quarantelli M, Larobina M, Volpe U, Amati G, Tedeschi E, Ciarmiello A, Brunetti A, Galderisi S, Alfano B
* Stereotaxy-based regional brain volumetry applied to segmented MRI: Validation and results in deficit and nondeficit schizophrenia (133 visite) (PDF 113 visite)
Neuroimage (ISSN: 1053-8119, 1053-8119linking), 2002 Sep; 17(1): 373-384.
Impact Factor: 5.624
Dettagli    Esporta in BibTeX    Esporta in EndNote

Brunetti A, Tedeschi G, Di Costanzo A, Covelli EM, Aloj L, Bonavita S, Ciarmiello A, Alfano B, Salvatore M
White matter lesion detection in multiple sclerosis: Improved interobserver concordance with multispectral MRI display (153 visite) (PDF 130 visite)
J Neurol (ISSN: 0340-5354, 1432-1459, 1432-1459electronic), 1997 Sep; 244(9): 586-590.
Impact Factor: 1.976
Dettagli    Esporta in BibTeX    Esporta in EndNote

Alfano B, Brunetti A
Advances in brain imaging: A new ethical challenge (108 visite) (PDF 183 visite)
Ann Ist Super Sanita (ISSN: 0021-2571), 1997; 33(4): 483-488.
Impact Factor: 0.343
Dettagli    Esporta in BibTeX    Esporta in EndNote



35 Records (30 escludendo Abstract e Conferenze).
Impact factor totale: 166.48 (154.188 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 184.775 (168.873 escludendo Abstract e Conferenze).







    Esporta in BibTeX    Esporta in EndNote