In vivo assessment of skin impedance recovery after low-voltage pulses electroporation (120 visite)
Imeko Tc Int Symp (ISSN: 9788-8903), 2008; N/D: 934-937.
Tipo di articolo: Journal Article,
Impact factor: 0, Impact factor a 5 anni: 0
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84883615660&partnerID=40&md5=440bc6fbcdedc6df768fb498facfc5d7
Parole chiave: After-Treatment, Electrical Impedance Spectroscopy, Electroporation, Frequency Ranges, Low-Voltage Pulse, Measurement Procedures, Skin Impedances, Square Wave Pulse, Drug Therapy, Electric Potential,
Affiliazioni:
*** IBB - CNR ***
Dipartimento di Ingegneria, Università del Sannio, Corso Garibaldi 107, 82100 Benevento, Italy
Consiglio Nazionale delle Ricerche, Istituto di Ingegneria Biomedica-Sez. Di Roma, Area di Ricerca Roma 1, Montelibretti, via Salaria km 29,300, 00016 Monterotondo S. (RM), Italy
Riferimenti:
Prausnitz, M.R., Bose, V.G., Langer, R., Weaver, J.C., Electroporation of mammalian skin: A mechanism to enhance transdermal drug delivery (1993) Proc. Natl. Acad. Sci. USA, 90, pp. 10504-1050
Vanbever, R., Lecouturier, N., Preat, V., Transdermal delivery of metoprolol by electroporation (1994) Pharm. Res, 11, pp. 1657-1662
Riviere, J.E., Monteiro-Riviere, N.A., Rogers, R.A., Bommannan, D., Tamada, J.A., Potts, R.O., Pulsatile transdermal delivery of LHRH using electroporation: Drug delivery and skin toxicology (1995) J. Control. Release, 36, pp. 229-233
Vanbever, R., Pliquett, U.F., Preat, V., Comparison of the effects of short, high-voltage and long, medium voltage pulses on skin electrical and transport properties (1999) J. Control. Release, 69, pp. 35-47
Lombry, C., Dujardin, N., Preat, V., Transdermal delivery of macromolecules using skin electroporation (2000) Pharm. Res, 17 (1), pp. 32-37
Titomirov, A.V., Sukharev, S., Kistanova, E., In vivo electroporation and stable transformation of skin cells of new born mice by plasmid DNA (1991) Biochem. Biophys. Acta, 1088, pp. 131-134
Heller, R., Jaroszeski, M., Atkin, A., Moradpour, D., Gilbert, R., Wands, J., Nicolau, C., In vivo gene electroinjection and expression in rat liver (1996) FEBS Lett, 389 (3), pp. 225-228
Nishi, T., Yoshizato, K., Yamashiro, S., Takeshima, H., Sato, K., Hamada, K., Kitamura, I., Ushio, Y., High-efficiency in vivo gene transfer using intraarterial plasmid DNA injection following in vivo electroporation (1996) Cancer Res, 56 (5), pp. 1050-1055
Mir, L.M., Bureau, M.F., Gehl, J., Rangara, R., Rouy, D., Caillaud, J.M., Delaere, P., Sherman, D., High efficiency gene transfer into skeletal muscle mediated by electric pulses (1999) Proc. Natl. Acad. Sci. USA, 96 (8), pp. 4262-4267
Regnier, V., Morre, N.D., Jadoul, A., Preat, V., Mechanism of a phosphorothioate oligonucleotide delivery by skin electroporation (1999) Int. J. Pharm, 184, pp. 147-156
Curdy, C., Naik, A., Kalia, Y.N., Alberti, I., Guy, R.H., Non-invasive assessment of the effect of formulation excipients on stratum corneum barrier function in vivo (2004) Int. J. of Pharm, 271, pp. 251-256
Dujardin, N., Staes, E., Kalia, Y., Clarys, P., Guy, R., Preat, V., In vivo assessment of skin electroporation using square wave pulses (2002) J. Control. Release, 79, pp. 219-227
Denet, A.R., Vanbever, R., Preat, V., Skin electroporation for transdermal and topical delivery (2004) Advanced Drug Delivery Reviews, 56, pp. 659-674
Arpaia, P., Clemente, F., Zanesco, A., Low-invasive diagnosis of metallic prosthesis osseointegration by electrical impedance spectroscopy (2007) IEEE Transaction on Instrumentation and Measurement, 56 (3), pp. 784-789
Arpaia, Clemente, F., Romanucci, C., Impedance spectroscopy-based measurement of cochlear prosthesis osseointegration: In-vivo test procedure and characterization (2007) Proc. of IMTC, pp. 1786-1791. , Warsaw (Poland)
Prausnitz, M. R., Bose, V. G., Langer, R., Weaver, J. C., Electroporation of mammalian skin: A mechanism to enhance transdermal drug delivery (1993) Proc. Natl. Acad. Sci. USA, 90, pp. 10504-1050
Riviere, J. E., Monteiro-Riviere, N. A., Rogers, R. A., Bommannan, D., Tamada, J. A., Potts, R. O., Pulsatile transdermal delivery of LHRH using electroporation: Drug delivery and skin toxicology (1995) J. Control. Release, 36, pp. 229-233
Titomirov, A. V., Sukharev, S., Kistanova, E., In vivo electroporation and stable transformation of skin cells of new born mice by plasmid DNA (1991) Biochem. Biophys. Acta, 1088, pp. 131-134
Mir, L. M., Bureau, M. F., Gehl, J., Rangara, R., Rouy, D., Caillaud, J. M., Delaere, P., Sherman, D., High efficiency gene transfer into skeletal muscle mediated by electric pulses (1999) Proc. Natl. Acad. Sci. USA, 96 (8), pp. 4262-4267
Denet, A. R., Vanbever, R., Preat, V., Skin electroporation for transdermal and topical delivery (2004) Advanced Drug Delivery Reviews, 56, pp. 659-674
Imeko Tc Int Symp (ISSN: 9788-8903), 2008; N/D: 934-937.
Tipo di articolo: Journal Article,
Impact factor: 0, Impact factor a 5 anni: 0
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84883615660&partnerID=40&md5=440bc6fbcdedc6df768fb498facfc5d7
Parole chiave: After-Treatment, Electrical Impedance Spectroscopy, Electroporation, Frequency Ranges, Low-Voltage Pulse, Measurement Procedures, Skin Impedances, Square Wave Pulse, Drug Therapy, Electric Potential,
Affiliazioni:
*** IBB - CNR ***
Dipartimento di Ingegneria, Università del Sannio, Corso Garibaldi 107, 82100 Benevento, Italy
Consiglio Nazionale delle Ricerche, Istituto di Ingegneria Biomedica-Sez. Di Roma, Area di Ricerca Roma 1, Montelibretti, via Salaria km 29,300, 00016 Monterotondo S. (RM), Italy
Riferimenti:
Prausnitz, M.R., Bose, V.G., Langer, R., Weaver, J.C., Electroporation of mammalian skin: A mechanism to enhance transdermal drug delivery (1993) Proc. Natl. Acad. Sci. USA, 90, pp. 10504-1050
Vanbever, R., Lecouturier, N., Preat, V., Transdermal delivery of metoprolol by electroporation (1994) Pharm. Res, 11, pp. 1657-1662
Riviere, J.E., Monteiro-Riviere, N.A., Rogers, R.A., Bommannan, D., Tamada, J.A., Potts, R.O., Pulsatile transdermal delivery of LHRH using electroporation: Drug delivery and skin toxicology (1995) J. Control. Release, 36, pp. 229-233
Vanbever, R., Pliquett, U.F., Preat, V., Comparison of the effects of short, high-voltage and long, medium voltage pulses on skin electrical and transport properties (1999) J. Control. Release, 69, pp. 35-47
Lombry, C., Dujardin, N., Preat, V., Transdermal delivery of macromolecules using skin electroporation (2000) Pharm. Res, 17 (1), pp. 32-37
Titomirov, A.V., Sukharev, S., Kistanova, E., In vivo electroporation and stable transformation of skin cells of new born mice by plasmid DNA (1991) Biochem. Biophys. Acta, 1088, pp. 131-134
Heller, R., Jaroszeski, M., Atkin, A., Moradpour, D., Gilbert, R., Wands, J., Nicolau, C., In vivo gene electroinjection and expression in rat liver (1996) FEBS Lett, 389 (3), pp. 225-228
Nishi, T., Yoshizato, K., Yamashiro, S., Takeshima, H., Sato, K., Hamada, K., Kitamura, I., Ushio, Y., High-efficiency in vivo gene transfer using intraarterial plasmid DNA injection following in vivo electroporation (1996) Cancer Res, 56 (5), pp. 1050-1055
Mir, L.M., Bureau, M.F., Gehl, J., Rangara, R., Rouy, D., Caillaud, J.M., Delaere, P., Sherman, D., High efficiency gene transfer into skeletal muscle mediated by electric pulses (1999) Proc. Natl. Acad. Sci. USA, 96 (8), pp. 4262-4267
Regnier, V., Morre, N.D., Jadoul, A., Preat, V., Mechanism of a phosphorothioate oligonucleotide delivery by skin electroporation (1999) Int. J. Pharm, 184, pp. 147-156
Curdy, C., Naik, A., Kalia, Y.N., Alberti, I., Guy, R.H., Non-invasive assessment of the effect of formulation excipients on stratum corneum barrier function in vivo (2004) Int. J. of Pharm, 271, pp. 251-256
Dujardin, N., Staes, E., Kalia, Y., Clarys, P., Guy, R., Preat, V., In vivo assessment of skin electroporation using square wave pulses (2002) J. Control. Release, 79, pp. 219-227
Denet, A.R., Vanbever, R., Preat, V., Skin electroporation for transdermal and topical delivery (2004) Advanced Drug Delivery Reviews, 56, pp. 659-674
Arpaia, P., Clemente, F., Zanesco, A., Low-invasive diagnosis of metallic prosthesis osseointegration by electrical impedance spectroscopy (2007) IEEE Transaction on Instrumentation and Measurement, 56 (3), pp. 784-789
Arpaia, Clemente, F., Romanucci, C., Impedance spectroscopy-based measurement of cochlear prosthesis osseointegration: In-vivo test procedure and characterization (2007) Proc. of IMTC, pp. 1786-1791. , Warsaw (Poland)
Prausnitz, M. R., Bose, V. G., Langer, R., Weaver, J. C., Electroporation of mammalian skin: A mechanism to enhance transdermal drug delivery (1993) Proc. Natl. Acad. Sci. USA, 90, pp. 10504-1050
Riviere, J. E., Monteiro-Riviere, N. A., Rogers, R. A., Bommannan, D., Tamada, J. A., Potts, R. O., Pulsatile transdermal delivery of LHRH using electroporation: Drug delivery and skin toxicology (1995) J. Control. Release, 36, pp. 229-233
Titomirov, A. V., Sukharev, S., Kistanova, E., In vivo electroporation and stable transformation of skin cells of new born mice by plasmid DNA (1991) Biochem. Biophys. Acta, 1088, pp. 131-134
Mir, L. M., Bureau, M. F., Gehl, J., Rangara, R., Rouy, D., Caillaud, J. M., Delaere, P., Sherman, D., High efficiency gene transfer into skeletal muscle mediated by electric pulses (1999) Proc. Natl. Acad. Sci. USA, 96 (8), pp. 4262-4267
Denet, A. R., Vanbever, R., Preat, V., Skin electroporation for transdermal and topical delivery (2004) Advanced Drug Delivery Reviews, 56, pp. 659-674
The aim of this work is to measure the skin impedance recovery after electroporation by using low-voltage pulse protocol on human subject. Before and after electroporation, based on square wave pulses of 20-50 V, 5 μs, for 15-20 minutes, Electrical Impedance Spectroscopy (EIS) measurements has been performed, in the frequency range 0.5-10 kHz. Preliminary experimental results show a significant decrease in skin impedance amplitude after treatment. This result turns out to be useful in a measurement procedure aimed at determining the amount of drug actually transferred in electroporation-based therapy.
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