Performance evaluation of the fully engineered YAP-(S)PET scanner for small animal imaging

Performance evaluation of the fully engineered YAP-(S)PET scanner for small animal imaging (100 visite)

Del Guerra A, Bartoli A, Belcari N, Herbert D, Motta A, Vaiano A, Di Domenico G, Sabba N, Moretti E, Zavattini G, Lazzarotti M, Sensi L, Larobina M

Ieee Transactions On Nuclear Science (ISSN: 0018-9499), 2006 Jun; 53(3): 1078-1083.

Tipo di articolo: Journal Article,

Impact factor: 1.497, Impact factor a 5 anni: 1.579

Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-33746379078&partnerID=40&md5=24191a5605eb1d4e67d5f9b316809f57

Parole chiave: Molecular Imaging, Positron Emission Tomography (pet), Single Photon Emission Tomography, Small Animal Imaging, Position Sensitive Photomultiplier (ps-Pmt), Imaging Techniques, Optical Collimators, Scanning, Sensitivity Analysis, Switching, Algorithms, Computer Simulation, Crystals, Electron Beam Computed Tomography, Photodiodes, Thin Films, Lutetium Oxyorthosilicate (lso) Crystals, Phantoms, Pixellated Array, Living Systems Studies,

Affiliazioni:

*** IBB - CNR ***
Department of Phyaics, Center of Excellence AmbiSEN and INFN Pisa, University of Pisa, I-56127 Pisa, Italy
Department of Physics, INFN Ferrara, University of Ferrara, I-44100 Ferrara, Italy
I.S.E. Ingegneria dei Sistemi Elettronici s.r.l., I-56010 Vecchiano (PI), Italy
CNR, Istituto di Biostrutture e Bioimmagini, I-80100 Napoli, Italy
Laboratory of Nuclear Medicine and Molecular Imaging, Department of Radiological Sciences, University of Ferrara, I-44100 Ferrara, Italy
C.N.R - Istituto di Biostrutture e Bioimmagini, Napoli, Italy
C. N. R - Istituto di Biostrutture e Bioimmagini, Napoli, Italy
I. S. E. Ingegneria dei Sistemi Elettronici s. r. l., I-56010 Vecchiano (PI), Italy

Riferimenti:

Del Guerra, A., Domenico, D., Scandola, M., Zavattini, G., High spatial resolution small animal YAPPET (1998) Nucl. Instrum. Methods Phys. Res., A409, pp. 537-54

Del Guerra, A., Damiani, C., Di Domenico, G., Motta, A., Sartori, L., Zavattini, G., An integrated PET-SPECT small animal imager: Preliminary results (2000) IEEE Trans. Nucl. Sci., 47 (4), pp. 1537-1540. , Aug

Del Guerra, A., Di Domenico, G., Gambaccini, M., Moretti, E., Sabba, N., Zavattini, G., Simultaneous PET/SPECT imaging with the small animal YAP-(S)PET scanner (2002) 2002 Annu. Conf. Academy of Molecular Imaging, , San Diego, CA, Oct. 23-27, in abstract

Del Guerra, A., Belcari, N., Herbert, D., Motta, A., Vaiano, A., Di Domenico, G., Moretti, E., Pinchera, A., Calibration and performance of the fully engineered YAP-(S)PET scanner for small rodents Small Animal SPECT Imaging, , M. A. Kupinski and H. H. Barrett, Eds. Norwell, MA: Kluwer, ch. 17

Motta, A., Damiani, C., Del Guerra, A., Di Domenico, G., Zavattini, G., Use of a fast deconvolution EM algorithm for 3-D imaging reconstruction with the YAP-PET tomograph (2002) Comput. Med. Imaging Graph., 26, pp. 293-302

(2001) NEMA Standards Publication NU2-2001: Performance Measurements of Positron Emission Tomographs, , NEMA Standards Publication NU2-2001, National Electrical Manufactures Association, Roulyn, VA

Yang, Y., Tai, Y.-C., Siegel, S., Newport, D.F., Bai, B., Li, Q., Leahy, R.M., Cherry, S.R., Optimization and performance evaluation of the microPET II scanner for in vivo small-animal imaging (2004) Phys. Med. Biol., 49, pp. 2527-2545

(1994) Performance Measurements of Positron Emission Tomographs, , NEMA Standards Publication NU2-1994, National Electrical Manufactures Association, Washington, DC

I.S.E. Ingegneria dei Sistemi Elettronici s.r.l., Vecchiano, Pisa, ItalyDel Guerra, A., Di Domenico, G., Gambaccini, M., Moretti, E., Sabba, N., Zavattini, G., Simultaneous PET/SPECT imaging with the small animal YAP-(S)PET scanner (2002) 2002 Annual Conference of the Academy of Molecular Imaging, , October 23-27, San Diego, CA, (USA) (abstract)

(1994) NEMA Standards Publication NU2-1994: Performance Measurements of Positron Emission Tomographs, , Washington, DC: National Electrical Manufactures Association

I. S. E. Ingegneria dei Sistemi Elettronici s. r. l., Vecchiano, Pisa, ItalyDel Guerra, A., Di Domenico, G., Gambaccini, M., Moretti, E., Sabba, N., Zavattini, G., Simultaneous PET/SPECT imaging with the small animal YAP- (S) PET scanner (2002) 2002 Annual Conference of the Academy of Molecular Imaging, , October 23-27, San Diego, CA, (USA) (abstract)

(2001) NEMA Standards Publication NU2-2001: Performance Measurements of Positron Emission Tomographs, , Rosslyn, VA: National Electrical Manufactures Association

(1994) NEMA Standards Publication NU2-1994: Performance Measurements of Positron Emission Tomographs, , Washington, DC: National Electrical Manufactures Association

Yang, Y., Tai, Y. -C., Siegel, S., Newport, D. F., Bai, B., Li, Q., Leahy, R. M., Cherry, S. R., Optimization and performance evaluation of the microPET II scanner for in vivo small-animal imaging (2004) Phys. Med. Biol., 49, pp. 2527-2545

(1994) Performance Measurements of Positron Emission Tomographs, , NEMA Standards Publication NU2-1994, National Electrical Manufactures Association, Washington, DC

At the Department of Physics of the University of Pisa, Italy, a new and fully engineered version of the YAP-(S)PET small animal scanner has been recently installed. The new YAP-(S)PET is able to perform both PET and SPECT studies on small animals. The scanner is made up of four heads: each one is composed of a 4 x 4 cm(2) YAlO3:Ce (or YAP:Ce) matrix of 20 x 20 elements, 2 x 2 x 25 mm(3) each, coupled to a Position Sensitive Photomultiplier (PS-PMT) (Hamamatsu R2486). The four modules are positioned on a rotating gantry. The switching to the SPECT modality is easily made by mounting a high resolution parallel hole (0.6 mm circle divide, 0.15 mm septum) lead collimator in front of each crystal. This paper reports the performance of the system in terms of absolute sensitivity and spatial resolution for both PET and SPECT modalities. The scatter fraction and noise-equivalent count rate (NEC) for a mouse phantom for different energy windows have been measured in PET modality. Images of phantoms and animals are also presented.

Interrogazione effettuata: [ptitle] "Molecular Imaging" OR [ptitle] "Positron Emission Tomography (pet)" OR [ptitle] "Single Photon Emission Tomography" OR [ptitle] "Small Animal Imaging" OR [ptitle] "Position Sensitive Photomultiplier (ps-Pmt)" OR [ptitle] "Imaging Techniques" OR [ptitle] "Optical Collimators"

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Interrogazione effettuata: [btitle, keywords] "Molecular Imaging" [btitle, keywords] "Positron Emission Tomography (pet)" [btitle, keywords] "Single Photon Emission Tomography" [btitle, keywords] "Small Animal Imaging" [btitle, keywords] "Position Sensitive Photomultiplier (ps-Pmt)" [btitle, keywords] "Imaging Techniques" [btitle, keywords] "Optical Collimators"

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Del Vecchio S, Zannetti A, Iommelli F, Lettieri A, Brunetti A, Salvatore M
* Molecular imaging of tumor microenvironment: Challenges and perspectives (211 visite)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2010 Jun; 54(3): 249-258.
Impact Factor: 1.724
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Varrone A, Sjoholm N, Eriksson L, Gulyas B, Halldin C, Farde L
* Advancement in PET quantification using 3D-OP-OSEM point spread function reconstruction with the HRRT (128 visite) (PDF 157 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2009 Oct; 36(10): 1639-1650.
Impact Factor: 4.531
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Cuocolo A, Concilio C, Acampa W, Ferro A, Evangelista L, Daniele S, Petretta M
* Cardiovascular risk stratification of diabetic patients (405 visite)
Minerva Endocrinol (ISSN: 0391-1977, 1827-1634electronic), 2009 Sep; 34(3): 205-221.
Impact Factor: 1.464
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Takano A, Gulyas B, Varrone A, Maguire RP, Halldin C
* Saturated norepinephrine transporter occupancy by atomoxetine relevant to clinical doses: A rhesus monkey study with (S, S)-[18F]FMeNER-D (157 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2009 Sep; 36(8): 1308-1314.
Impact Factor: 4.531
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Alfano B, Larobina M, Salvatore M
* Technological platforms for molecular imaging: A vision of the future (156 visite) (PDF 130 visite)
Minerva Biotecnol (ISSN: 1120-4826), 2009 Jun; 21(2): 67-75.
Impact Factor: 0.268
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Mancini M, Greco A, Speranza A, Salvatore M
* Ultrasound molecular imaging by targeted microbubble contrast agents (176 visite)
Minerva Biotecnol (ISSN: 1120-4826), 2009 Jun; 21(2): 97-110.
Impact Factor: 0.268
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Del Vecchio S, Zannetti A, Fonti R, Iommelli F, Lettieri A, Salvatore M
* Molecular imaging of drug resistance in cancer (156 visite)
Minerva Biotecnol (ISSN: 1120-4826), 2009 Mar; 21(1): 31-36.
Impact Factor: 0.268
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Lucignani G, Salvatore M
* Biotechnology in molecular and cellular imaging (110 visite)
Minerva Biotecnol (ISSN: 1120-4826), 2009; 21(1): 1-3.
Impact Factor: 0.268
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Tammaro V, Spiezia S, D'Angelo S, Maurea S, Ciolli G, Salvatore M
* Diagnostic Imaging Techniques for Synchronous Multiple Tumors (99 visite)
Multiple Primary Malignancies, 2009; N/D: N/D-N/D.
Impact Factor: 0
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Brunetti A, Cuocolo A
* European Science Foundation calls for more and better medical imaging research (78 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2008 Sep; 35(9): 1749-1757.
Impact Factor: 4.532
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Maggi A, Salvatore M
Molecular imaging (142 visite)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2007 Jun; 51(2): 95-95.
Impact Factor: 1.724
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Del Vecchio S, Zannetti A, Fonti R, Pace L, Salvatore M
* Nuclear imaging in cancer theranostics (262 visite)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2007 Jun; 51(2): 152-163.
Impact Factor: 1.724
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Cusanno F, Cisbani E, Colilli S, Fratoni R, Garibaldi F, Giuliani F, Gricia M, Lucentini M, Magliozzi ML, Santarivenere F, Torrioli S, Cinti MN, Pani R, Pellegrini R, Simonetti G, Schillaci O, Del Vecchio S, Salvatore M, Majewski S, De Vincentis G, Scopinaro F
* Results of clinical trials with SPEM (119 visite)
Nucl Instrum Methods Phys Res Sect A, 2007 Feb 1; 497(1): 46-50.
Impact Factor: 3.221
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Garibaldi F, Cisbani E, Colilli S, Cusanno F, Fratoni R, Giuliani F, Gricia M, Lucentini M, Fratoni R, Lo Meo S, Magliozzi ML, Santanvenere F, Cinti MN, Pani R, Pellegrini R, Simonetti G, Schillaci O, Del Vecchio S, Salvatore M, Majewski S, Lanza RC, De Vincentis G, Scopinaro F
* Molecular imaging: High-resolution detectors for early diagnosis and therapy monitoring of breast cancer (137 visite)
Nucl Instrum Meth A (ISSN: 0168-9002), 2006 Dec 20; 569(2SPEC.ISS.): 286-290.
Impact Factor: 1.185
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Mainenti PP, Cirillo LC, Camera L, Persico F, Cantalupo T, Pace L, De Palma GD, Persico G, Salvatore M
* Accuracy of single phase contrast enhanced multidetector CT colonography in the preoperative staging of colo-rectal cancer (121 visite)
Eur J Radiol (ISSN: 0720-048x), 2006 Dec; 60(3): 453-459.
Impact Factor: 1.332
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D'Agata R, Grasso G, Iacono G, Spoto G, Vecchio G
* Lectin recognition of a new SOD mimic bioconjugate studied with surface plasmon resonance imaging (108 visite)
Org Biomol Chem (ISSN: 1477-0520, 1477-0539, 1477-0539electronic), 2006 Feb 21; 4(4): 610-612.
Impact Factor: 2.874
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Del Guerra A, Bartoli A, Belcari N, Herbert A, Motta A, Vaiano A, Di Domenico G, Sabbia N, Moretti E, Zavattini G, Lazzarotti M, Sensi L, Larobina M, Uccelli L
* Performance Evalutation Of The Fully Engineered Yap-(s) Pet Scanner For Small Animal Imaging (88 visite)
Ieee Transactions On Nuclear Science, 2006; 53: 1078-1083.
Impact Factor: 1.455
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Mansi R, Tesauro D, De Capua A, Fattorusso R, Carac C, Aloj L, Benedetti E, Morelli G
* Peptide-chelating agent conjugate for selective targeting of somatostatin receptor type 1: Synthesis and characterization (167 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2004; 76(6): 527-534.
Impact Factor: 2.863
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Del Guerra A, Bartoli A, Belcari N, Herbert D, Motta A, Vaiano A, Di Domenico G, Sabba N, Moretti E, Zavattini G, Lazzarotti M, Sensi L, Larobina M
* Performance evaluation of the fully engineered YAP-(S)PET scanner for small animal imaging (143 visite)
2004 Ieee Nuclear Science Symposium Conference Record Vols 1 7, 2004; 5: 2990-2994.
Impact Factor: 0
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Kim KM, Watabe H, Varrone A, Fujita M, Innis RB, Iida H
* Evaluation of Two Scatter Correction Methods in Quantitative Brain SPECT with Dopaminergic Tracer (103 visite)
Ieee Nucl Sci Symp Med Imaging Conf, 2002; 3: 1792-1796.
Impact Factor: 0.155
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Celentano L, Laccetti P, Liuzzi R, Mettivier G, Montesi MC, Autiero M, Riccio P, Roberti G, Russo P, Salvatore M
* Preliminary tests of a prototype system for optical and radionuclide imaging in small animals (117 visite)
Ieee Nuclear Science Symposium And Medical Imaging Conference, 2002; 3: 1746-1750.
Impact Factor: 0
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De Michele G, Mainenti PP, Soricelli A, Di Salle F, Salvatore E, Longobardi MR, Postiglione A, Salvatore M, Filla A
Cerebral blood flow in spinocerebellar degenerations: a single photon emission tomography study in 28 patients (107 visite)
J Neurol (ISSN: 0340-5354, 1432-1459, 1432-1459electronic), 1998 Sep; 245(9): 603-608.
Impact Factor: 2.3
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Maurea S, Mainolfi C, Wang H, Varrella P, Panico M, Klain M, Rossi R, Cremona F, Bazzicalupo L, Salvatore M
Positron Emission Tomography (pet) With Fludeoxyglucose F 18 In The Study Of Adrenal Masses: Comparison Of Benign And Malignant Lesions (103 visite)
Radiol Med, 1996 Dec; 92(6): 782-787.
Impact Factor: 0
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Soricelli A, Mainenti PP, Leone D, Discepolo A, Romano M, Varrone A, Servillo G, Serio S, Brunetti A, Salvatore M
Evaluation of brain perfusion with high resolution single photon emission tomography in the diagnosis of brain death (119 visite)
Minerva Anestesiol (ISSN: 0375-9393), 1996 Jun; 62(6): 209-212.
Impact Factor: 1.627
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67 Records (62 escludendo Abstract e Conferenze).
Impact factor totale: 219.923 (213.286 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 205.977 (199.323 escludendo Abstract e Conferenze).

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