Performance evaluation of the fully engineered YAP-(S)PET scanner for small animal imaging
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Performance evaluation of the fully engineered YAP-(S)PET scanner for small animal imaging (203 views visite)

Del Guerra A, Bartoli A, Belcari N, Herbert D, Motta A, Vaiano A, Di Domenico G, Sabba N, Moretti E, Zavattini G, Lazzarotti M, Sensi L, Larobina M

Ieee Transactions On Nuclear Science (ISSN: 0018-9499), 2006 Jun; 53(3): 1078-1083.



Paper type Tipo di articolo: Journal Article,

Impact factor: 1.497, 5-year impact factor Impact factor a 5 anni: 1.579

Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-33746379078&partnerID=40&md5=24191a5605eb1d4e67d5f9b316809f57

Keywords Parole chiave: Molecular Imaging, Positron Emission Tomography (pet), Single Photon Emission Tomography, Small Animal Imaging, Position Sensitive Photomultiplier (ps-Pmt), Imaging Techniques, Optical Collimators, Scanning, Sensitivity Analysis, Switching, Algorithms, Computer Simulation, Crystals, Electron Beam Computed Tomography, Photodiodes, Thin Films, Lutetium Oxyorthosilicate (lso) Crystals, Phantoms, Pixellated Array, Living Systems Studies,

Affiliations Affiliazioni:

*** IBB - CNR ***
Department of Phyaics, Center of Excellence AmbiSEN and INFN Pisa, University of Pisa, I-56127 Pisa, Italy
Department of Physics, INFN Ferrara, University of Ferrara, I-44100 Ferrara, Italy
I.S.E. Ingegneria dei Sistemi Elettronici s.r.l., I-56010 Vecchiano (PI), Italy
CNR, Istituto di Biostrutture e Bioimmagini, I-80100 Napoli, Italy
Laboratory of Nuclear Medicine and Molecular Imaging, Department of Radiological Sciences, University of Ferrara, I-44100 Ferrara, Italy
C.N.R - Istituto di Biostrutture e Bioimmagini, Napoli, Italy
C. N. R - Istituto di Biostrutture e Bioimmagini, Napoli, Italy
I. S. E. Ingegneria dei Sistemi Elettronici s. r. l., I-56010 Vecchiano (PI), Italy


References Riferimenti:

Del Guerra, A., Domenico, D., Scandola, M., Zavattini, G., High spatial resolution small animal YAPPET (1998) Nucl. Instrum. Methods Phys. Res., A409, pp. 537-54

Del Guerra, A., Damiani, C., Di Domenico, G., Motta, A., Sartori, L., Zavattini, G., An integrated PET-SPECT small animal imager: Preliminary results (2000) IEEE Trans. Nucl. Sci., 47 (4), pp. 1537-1540. , Aug

Del Guerra, A., Di Domenico, G., Gambaccini, M., Moretti, E., Sabba, N., Zavattini, G., Simultaneous PET/SPECT imaging with the small animal YAP-(S)PET scanner (2002) 2002 Annu. Conf. Academy of Molecular Imaging, , San Diego, CA, Oct. 23-27, in abstract

Del Guerra, A., Belcari, N., Herbert, D., Motta, A., Vaiano, A., Di Domenico, G., Moretti, E., Pinchera, A., Calibration and performance of the fully engineered YAP-(S)PET scanner for small rodents Small Animal SPECT Imaging, , M. A. Kupinski and H. H. Barrett, Eds. Norwell, MA: Kluwer, ch. 17

Motta, A., Damiani, C., Del Guerra, A., Di Domenico, G., Zavattini, G., Use of a fast deconvolution EM algorithm for 3-D imaging reconstruction with the YAP-PET tomograph (2002) Comput. Med. Imaging Graph., 26, pp. 293-302

(2001) NEMA Standards Publication NU2-2001: Performance Measurements of Positron Emission Tomographs, , NEMA Standards Publication NU2-2001, National Electrical Manufactures Association, Roulyn, VA

Yang, Y., Tai, Y.-C., Siegel, S., Newport, D.F., Bai, B., Li, Q., Leahy, R.M., Cherry, S.R., Optimization and performance evaluation of the microPET II scanner for in vivo small-animal imaging (2004) Phys. Med. Biol., 49, pp. 2527-2545

(1994) Performance Measurements of Positron Emission Tomographs, , NEMA Standards Publication NU2-1994, National Electrical Manufactures Association, Washington, DC

I.S.E. Ingegneria dei Sistemi Elettronici s.r.l., Vecchiano, Pisa, ItalyDel Guerra, A., Di Domenico, G., Gambaccini, M., Moretti, E., Sabba, N., Zavattini, G., Simultaneous PET/SPECT imaging with the small animal YAP-(S)PET scanner (2002) 2002 Annual Conference of the Academy of Molecular Imaging, , October 23-27, San Diego, CA, (USA) (abstract)

(1994) NEMA Standards Publication NU2-1994: Performance Measurements of Positron Emission Tomographs, , Washington, DC: National Electrical Manufactures Association

I. S. E. Ingegneria dei Sistemi Elettronici s. r. l., Vecchiano, Pisa, ItalyDel Guerra, A., Di Domenico, G., Gambaccini, M., Moretti, E., Sabba, N., Zavattini, G., Simultaneous PET/SPECT imaging with the small animal YAP- (S) PET scanner (2002) 2002 Annual Conference of the Academy of Molecular Imaging, , October 23-27, San Diego, CA, (USA) (abstract)

(2001) NEMA Standards Publication NU2-2001: Performance Measurements of Positron Emission Tomographs, , Rosslyn, VA: National Electrical Manufactures Association

(1994) NEMA Standards Publication NU2-1994: Performance Measurements of Positron Emission Tomographs, , Washington, DC: National Electrical Manufactures Association

Yang, Y., Tai, Y. -C., Siegel, S., Newport, D. F., Bai, B., Li, Q., Leahy, R. M., Cherry, S. R., Optimization and performance evaluation of the microPET II scanner for in vivo small-animal imaging (2004) Phys. Med. Biol., 49, pp. 2527-2545

(1994) Performance Measurements of Positron Emission Tomographs, , NEMA Standards Publication NU2-1994, National Electrical Manufactures Association, Washington, DC



At the Department of Physics of the University of Pisa, Italy, a new and fully engineered version of the YAP-(S)PET small animal scanner has been recently installed. The new YAP-(S)PET is able to perform both PET and SPECT studies on small animals. The scanner is made up of four heads: each one is composed of a 4 x 4 cm(2) YAlO3:Ce (or YAP:Ce) matrix of 20 x 20 elements, 2 x 2 x 25 mm(3) each, coupled to a Position Sensitive Photomultiplier (PS-PMT) (Hamamatsu R2486). The four modules are positioned on a rotating gantry. The switching to the SPECT modality is easily made by mounting a high resolution parallel hole (0.6 mm circle divide, 0.15 mm septum) lead collimator in front of each crystal. This paper reports the performance of the system in terms of absolute sensitivity and spatial resolution for both PET and SPECT modalities. The scatter fraction and noise-equivalent count rate (NEC) for a mouse phantom for different energy windows have been measured in PET modality. Images of phantoms and animals are also presented.
No results. Nessun risultato.
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Protein Sci (ISSN: 0961-8368, 1469-896xelectronic), 2001 Dec; 10(12): 2627-2632.
Impact Factor: 3.472
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31 Records (28 escludendo Abstract e Conferenze).
Impact factor totale: 94.229 (91.557 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 99.696 (96.205 escludendo Abstract e Conferenze).







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