99mTc tetrofosmin cardiac tomography after nitrate administration in patients with coronary artery disease and left vetricular dysfunction(283 views visite) Menna F, Acampa W, Florimonte L, Ferro A, Borrelli G, Mainolfi C, Cuocolo A
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 2000; 99(4): 258-263.
Affiliations Affiliazioni: Centro per la Med. Nucleare del CNR, Universita Federico II, Via Pansini 5, 80131 Napoli NA, Italy
References Riferimenti: Not available. Non disponibili.
99mTc tetrofosmin cardiac tomography after nitrate administration in patients with coronary artery disease and left vetricular dysfunction
Purpose. To investigate the role of technetium-99m (99mTc) tetrofosmin single-photon emission Computed Tomography (SPECT) associated with nitrate administration in the detection of hypoperfused but still viable myocardium in patients with chronic coronary artery disease and left ventricular (LV) dysfunction. Material and methods. Twenty-two patients (mean age 54±11 years) with coronary artery disease, previous myocardial infarction and LV dysfunction (LV ejection fraction 38±13%) were examined. On differente days all patients underwent 99mTc tetrofosmin (740 MBq) SPECT under control conditions at rest and after sublingual nitroglycerin administration (10 mg). Regional tetrofosmin activity was quantitatively measured in 22 myocardial segments per patient. In each segment, tracer uptake was expressed as a percentage of the region with the peak activity. Results. Under control conditions, 267 myocardial segments (55%) showed normal tetrofosmin uptake (>70% of peak activity), 107 segments (22%) showed a moderate reduction (51- 70%) and 110 segments (23%) a severe reduction (≤50%) in tracer uptake. Among the 110 segments with a severe reduction in tetrofosmin uptake 20 (18%) showed increased tracer uptake ≥10% of after nitrate administration (from 44±5% to 58±3%, p
99mTc tetrofosmin cardiac tomography after nitrate administration in patients with coronary artery disease and left vetricular dysfunction
134 Records (116 escludendo Abstract e Conferenze). Impact factor totale: 385.64 (319.158 escludendo Abstract e Conferenze). Impact factor a 5 anni totale: 462.969 (381.591 escludendo Abstract e Conferenze).
Last modified by Ultima modifica di Marco Comerci on in data Sunday 12 July 2020, 13:15:13 283 views visite. Last view on Ultima visita in data Sunday 28 March 2021, 21:43:35