Sonosensitive theranostic liposomes for preclinical in vivo MRI-guided visualization of doxorubicin release stimulated by pulsed low intensity non-focused ultrasound (327 visite)
J Control Release (ISSN: 0168-3659), 2015 Jan 24; 202: 21-30.
Tipo di articolo: Journal Article,
Impact factor: 7.441, Impact factor a 5 anni: 8.407
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84921957698&partnerID=40&md5=b3ea740a30eba97245ac851bcc56ea81
Parole chiave: Chemotherapy, Drug Products, Fluorescence Microscopy, Medical Nanotechnology, Tumors, Ultrasonic Applications, Antitumor Drugs, Focused Ultrasound, Imaging Agent, Mri Contrasts, Theranostic Agents, Therapeutic Benefits, Therapeutic Outcomes, Translatability, Liposomes, Doxorubicin, Gadoteridol, Animal Cell, Animal Experiment, Animal Model, Article, Breast Cancer, Cancer Cell, Confocal Microscopy, Contrast Enhancement, Contrast To Noise Ratio, Controlled Study, Drug Release, Ex Vivo Study, Female, In Vitro Study, In Vivo Study, Liposomal Delivery, Mouse, Nonhuman, Nuclear Magnetic Resonance Imaging, Priority Journal, Pulsed Low Intensity Non Focused Ultrasound,
Affiliazioni:
*** IBB - CNR ***
Center for Molecular Imaging, Department of Molecular Biotechnology and Health Sciences, University of Torino, Via Nizza 52Torino, Italy
Center for Preclinical Imaging, Department of Molecular Biotechnology and Health Sciences, University of Torino, Via Ribes 5Colleretto Giacosa (TO), Italy
Institute for Biostructures and Bioimages (CNR), C/o Molecular Biotechnology Center, University of Torino, Italy
Biolab, Department of Electronics and Telecommunications, Politecnico di TorinoTorino, Italy
Riferimenti:
Terreno, E., Uggeri, F., Aime, S., Image guided therapy: The advent of theranostic agents (2012) J. Control. Release, 161 (2), pp. 328-33
Prabhu, P., Patravale, V., The upcoming field of theranostic nanomedicine: An overview (2012) J. Biomed. Nanotechnol., 8 (6), pp. 859-882
Sumer, B., Gao, J.M., Theranostic nanomedicine for cancer (2008) Nanomedicine, 3 (2), pp. 137-140
Weissleder, R., Pittet, M.J., Imaging in the era of molecular oncology (2008) Nature, 452 (7187), pp. 580-589
Massoud, T.F., Gambhir, S.S., Molecular imaging in living subjects: Seeing fundamental biological processes in a new light (2003) Genes Dev., 17 (5), pp. 545-580
Weissleder, R., Molecular imaging: Exploring the next frontier (1999) Radiology, 212 (3), pp. 609-614
Jacobs, R.E., Cherry, S.R., Complementary emerging techniques: High-resolution PET and MRI (2001) Curr. Opin. Neurobiol., 11 (5), pp. 621-629
Manzoor, A.A., Overcoming limitations in nanoparticle drug delivery: Triggered, intravascular release to improve drug penetration into tumors (2012) Cancer Res., 72 (21), pp. 5566-5575
Lammers, T., Theranostic nanomedicine (2011) Acc. Chem. Res., 44 (10), pp. 1029-1038
Torchilin, V., Liposomes in drug delivery (2012) Fundamentals and Applications of Controlled Release Drug Delivery, pp. 289-328. , J. Siepmann, R.A. Siegel, M.J. Rathbone, Springer New York
Ponce, A.M., Hyperthermia mediated liposomal drug delivery (2006) Int. J. Hyperth., 22 (3), pp. 205-213
Koning, G.A., Hyperthermia and thermosensitive liposomes for improved delivery of chemotherapeutic drugs to solid tumors (2010) Pharm. Res., 27 (8), pp. 1750-1754
Needham, D., A new temperature-sensitive liposome for use with mild hyperthermia: Characterization and testing in a human tumor xenograft model (2000) Cancer Res., 60 (5), pp. 1197-1201
Torres, E., Improved paramagnetic liposomes for MRI visualization of pH triggered release (2011) J. Control. Release, 154 (2), pp. 196-202
Kuppusamy, P., Noninvasive imaging of tumor redox status and its modification by tissue glutathione levels (2002) Cancer Res., 62 (1), pp. 307-312
Mellal, D., Zumbuehl, A., Exit-strategies - Smart ways to release phospholipid vesicle cargo (2014) J. Mater. Chem. B, 2 (3), pp. 247-252
Zhu, L., Torchilin, V.P., Stimulus-responsive nanopreparations for tumor targeting (2013) Integr. Biol., 5 (1), pp. 96-107
Singh, R., Torti, S.V., Carbon nanotubes in hyperthermia therapy (2013) Adv. Drug Deliv. Rev., 65 (15), pp. 2045-2060
Bazrafshan, B., Temperature imaging of laser-induced thermotherapy (LITT) by MRI: Evaluation of different sequences in phantom (2014) Lasers Med. Sci., 29 (1), pp. 173-183
Kostrzewa, M., Microwave ablation of osteoid osteomas using dynamic MR imaging for early treatment assessment: Preliminary experience (2014) J. Vasc. Interv. Radiol., 25 (1), pp. 106-111
De Smet, M., Magnetic resonance guided high-intensity focused ultrasound mediated hyperthermia improves the intratumoral distribution of temperature-sensitive liposomal doxorubicin (2013) Investig. Radiol., 48 (6), pp. 395-405
Grull, H., Langereis, S., Hyperthermia-triggered drug delivery from temperature-sensitive liposomes using MRI-guided high intensity focused ultrasound (2012) J. Control. Release, 161 (2), pp. 317-327
Negussie, A.H., Formulation and characterisation of magnetic resonance imageable thermally sensitive liposomes for use with magnetic resonance-guided high intensity focused ultrasound (2011) Int. J. Hyperth., 27 (2), pp. 140-155
Ranjan, A., Image-guided drug delivery with magnetic resonance guided high intensity focused ultrasound and temperature sensitive liposomes in a rabbit Vx2 tumor model (2012) J. Control. Release, 158 (3), pp. 487-494
Li, L., Mild hyperthermia triggered doxorubicin release from optimized stealth thermosensitive liposomes improves intratumoral drug delivery and efficacy (2013) J. Control. Release, 168 (2), pp. 142-150
Lanza, G.M., Assessing the barriers to image-guided drug delivery (2014) Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol., 6 (1), pp. 1-14
Fernando, R., MRI-guided monitoring of thermal dose and targeted drug delivery for cancer therapy (2013) Pharm. Res., 30 (11), pp. 2709-2717
Dewhirst, M.W., Novel Approaches to Treatment of Hepatocellular Carcinoma and Hepatic Metastases Using Thermal Ablation and Thermosensitive Liposomes (2013) Surgical Oncology Clinics of North America, 22 (3), pp. 545-561
McDaniel, J.R., Dewhirst, M.W., Chilkoti, A., Actively targeting solid tumours with thermoresponsive drug delivery systems that respond to mild hyperthermia (2013) Int. J. Hyperth., 29 (6), pp. 501-510
Sharma, D., Chelvi, T.P., Ralhan, R., Thermosensitive liposomal taxol formulation: Heat-mediated targeted drug delivery in murine melanoma (1998) Melanoma Res., 8 (3), pp. 240-244
Papahadjopoulos, D., Phase transitions in phospholipid vesicles. Fluorescence polarization and permeability measurements concerning the effect of temperature and cholesterol (1973) Biochim. Biophys. Acta, 311 (3), pp. 330-348
Dicheva, B.M., Koning, G.A., Targeted thermosensitive liposomes: An attractive novel approach for increased drug delivery to solid tumors (2014) Expert Opin. Drug Deliv., 11 (1), pp. 83-100
Li, L., A novel two-step mild hyperthermia for advanced liposomal chemotherapy (2014) J. Control. Release, 174, pp. 202-208
Nakayama, M., Akimoto, J., Okano, T., Polymeric micelles with stimuli-triggering systems for advanced cancer drug targeting (2014) J. Drug Target., 22 (7), pp. 584-599
May, J.P., Li, S.D., Hyperthermia-induced drug targeting (2013) Expert Opin. Drug Deliv., 10 (4), pp. 511-527
Needham, D., Materials characterization of the low temperature sensitive liposome (LTSL): Effects of the lipid composition (lysolipid and DSPE-PEG2000) on the thermal transition and release of doxorubicin (2013) Faraday Discuss., 161, pp. 515-534
Langereis, S., Paramagnetic liposomes for molecular MRI and MRI-guided drug delivery (2013) NMR Biomed., 26 (7), pp. 728-744
Wang, S., Pulsed high intensity focused ultrasound increases penetration and therapeutic efficacy of monoclonal antibodies in murine xenograft tumors (2012) J. Control. Release, 162 (1), pp. 218-224
Chen, X.Y., Gambhlr, S.S., Cheon, J., Theranostic nanomedicine (2011) Acc. Chem. Res., 44 (10). , p. 841
Lin, C.Y., Ultrasound sensitive eLiposomes containing doxorubicin for drug targeting therapy (2014) Nanomedicine, 10 (1), pp. 67-76
Lin, H.Y., Thomas, J.L., Factors affecting responsivity of unilamellar liposomes to 20 kHz ultrasound (2004) Langmuir, 20 (15), pp. 6100-6106
Evjen, T.J., In vivo monitoring of liposomal release in tumours following ultrasound stimulation (2013) Eur. J. Pharm. Biopharm., 84 (3), pp. 526-531
Giustetto, P., Release of a paramagnetic magnetic resonance imaging agent from liposomes triggered by low intensity non-focused ultrasound (2013) J. Med. Imaging Health Inform., 3 (3), pp. 356-366
Datta, S., Correlation of cavitation with ultrasound enhancement of thrombolysis (2006) Ultrasound Med. Biol., 32 (8), pp. 1257-1267
Schroeder, A., Kost, J., Barenholz, Y., Ultrasound, liposomes, and drug delivery: Principles for using ultrasound to control the release of drugs from liposomes (2009) Chem. Phys. Lipids, 162 (12), pp. 1-16
Yudina, A., Ultrasound-mediated intracellular drug delivery using microbubbles and temperature-sensitive liposomes (2011) J. Control. Release, 155 (3), pp. 442-448
Schroeder, A., Controlling liposomal drug release with low frequency ultrasound: Mechanism and feasibility (2007) Langmuir, 23 (7), pp. 4019-4025
Afadzi, M., Mechanisms of the ultrasound-mediated intracellular delivery of liposomes and dextrans (2013) IEEE Trans. Ultrason. Ferroelectr. Freq. Control, 60 (1), pp. 21-33
Staples, B.J., Role of frequency and mechanical index in ultrasonic-enhanced chemotherapy in rats (2009) Cancer Chemother. Pharmacol., 64 (3), pp. 593-600
Knodler, M., An analysis of toxicity in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck (R/M SCCHN) receiving cetuximab, fluorouracil and cisplatin alone or with docetaxel in a phase II clinical trial (CeFCiD) (2012) Onkologie, 35, p. 153
Fattahi, H., Magnetoliposomes as multimodal contrast agents for molecular imaging and cancer nanotheragnostics (2011) Nanomedicine, 6 (3), pp. 529-544
Aime, S., Pushing the sensitivity envelope of lanthanide-based magnetic resonance imaging (MRI) contrast agents for molecular imaging applications (2009) Acc. Chem. Res., 42 (7), pp. 822-831
Terreno, E., Paramagnetic liposomes as innovative contrast agents for magnetic resonance (MR) molecular imaging applications (2008) Chem. Biodivers., 5 (10), pp. 1901-1912
Fossheim, S.L., Paramagnetic liposomes as MRI contrast agents: Influence of liposomal physicochemical properties on the in vitro relaxivity (1999) Magn. Reson. Imaging, 17 (1), pp. 83-89
Castelli, D.D., Metal containing nanosized systems for MR-molecular imaging applications (2008) Coord. Chem. Rev., 252 (2122), pp. 2424-2443
Rizzitelli, S., Giustetto, P., Boffa, C., Delli Castelli, D., Cutrin, J.C., Aime, S., Terreno, E., In vivo MRI visualization of release from liposomes triggered by local application of pulsed low intensity non focused ultrasound (2014) Nanomedicine, 10 (5), pp. 901-904
Barge, A., How to determine free Gd and free ligand in solution of Gd chelates. A technical note (2006) Contrast Media Mol. Imaging, 1 (5), pp. 184-188
Nanni, P., TS/A: A new metastasizing cell line from a BALB/c spontaneous mammary adenocarcinoma (1983) Clin. Exp. Metastasis, 1 (4), pp. 373-380
Steckner, M.C., Liu, B., Ying, L., A new single acquisition, two-image difference method for determining MR image SNR (2009) Med. Phys., 36 (2), pp. 662-671
Dietrich, O., Measurement of signal-to-noise ratios in MR images: Influence of multichannel coils, parallel imaging, and reconstruction filters (2007) J. Magn. Reson. Imaging, 26 (2), pp. 375-385
Henkelman, R.M., Measurement of signal intensities in the presence of noise in mr images (1985) Med. Phys., 12 (2), pp. 232-233
Castellano, G., Li, L.M., Cendes, F., Texture analysis of medical images (2004) Clin. Radiol., 59 (12), pp. 1061-1069
Haralick, R.M., Dinstein, I.H., Textural features for image classification (1973) IEEE Trans. Syst. Man Cybern., 3 (6), pp. 610-621. , SMC
Da, A.A.J.R., Quantification of histochemical staining by color deconvolution (2001) Anal. Quant. Cytol. Histol., 23 (4), pp. 291-299
Sumer, B., Gao, J. M., Theranostic nanomedicine for cancer (2008) Nanomedicine, 3 (2), pp. 137-140
Massoud, T. F., Gambhir, S. S., Molecular imaging in living subjects: Seeing fundamental biological processes in a new light (2003) Genes Dev., 17 (5), pp. 545-580
Jacobs, R. E., Cherry, S. R., Complementary emerging techniques: High-resolution PET and MRI (2001) Curr. Opin. Neurobiol., 11 (5), pp. 621-629
Manzoor, A. A., Overcoming limitations in nanoparticle drug delivery: Triggered, intravascular release to improve drug penetration into tumors (2012) Cancer Res., 72 (21), pp. 5566-5575
Ponce, A. M., Hyperthermia mediated liposomal drug delivery (2006) Int. J. Hyperth., 22 (3), pp. 205-213
Koning, G. A., Hyperthermia and thermosensitive liposomes for improved delivery of chemotherapeutic drugs to solid tumors (2010) Pharm. Res., 27 (8), pp. 1750-1754
Negussie, A. H., Formulation and characterisation of magnetic resonance imageable thermally sensitive liposomes for use with magnetic resonance-guided high intensity focused ultrasound (2011) Int. J. Hyperth., 27 (2), pp. 140-155
Lanza, G. M., Assessing the barriers to image-guided drug delivery (2014) Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol., 6 (1), pp. 1-14
Dewhirst, M. W., Novel Approaches to Treatment of Hepatocellular Carcinoma and Hepatic Metastases Using Thermal Ablation and Thermosensitive Liposomes (2013) Surgical Oncology Clinics of North America, 22 (3), pp. 545-561
McDaniel, J. R., Dewhirst, M. W., Chilkoti, A., Actively targeting solid tumours with thermoresponsive drug delivery systems that respond to mild hyperthermia (2013) Int. J. Hyperth., 29 (6), pp. 501-510
Dicheva, B. M., Koning, G. A., Targeted thermosensitive liposomes: An attractive novel approach for increased drug delivery to solid tumors (2014) Expert Opin. Drug Deliv., 11 (1), pp. 83-100
May, J. P., Li, S. D., Hyperthermia-induced drug targeting (2013) Expert Opin. Drug Deliv., 10 (4), pp. 511-527
Chen, X. Y., Gambhlr, S. S., Cheon, J., Theranostic nanomedicine (2011) Acc. Chem. Res., 44 (10). , p. 841
Lin, C. Y., Ultrasound sensitive eLiposomes containing doxorubicin for drug targeting therapy (2014) Nanomedicine, 10 (1), pp. 67-76
Lin, H. Y., Thomas, J. L., Factors affecting responsivity of unilamellar liposomes to 20 kHz ultrasound (2004) Langmuir, 20 (15), pp. 6100-6106
Evjen, T. J., In vivo monitoring of liposomal release in tumours following ultrasound stimulation (2013) Eur. J. Pharm. Biopharm., 84 (3), pp. 526-531
Staples, B. J., Role of frequency and mechanical index in ultrasonic-enhanced chemotherapy in rats (2009) Cancer Chemother. Pharmacol., 64 (3), pp. 593-600
Fossheim, S. L., Paramagnetic liposomes as MRI contrast agents: Influence of liposomal physicochemical properties on the in vitro relaxivity (1999) Magn. Reson. Imaging, 17 (1), pp. 83-89
Castelli, D. D., Metal containing nanosized systems for MR-molecular imaging applications (2008) Coord. Chem. Rev., 252 (2122), pp. 2424-2443
Steckner, M. C., Liu, B., Ying, L., A new single acquisition, two-image difference method for determining MR image SNR (2009) Med. Phys., 36 (2), pp. 662-671
Henkelman, R. M., Measurement of signal intensities in the presence of noise in mr images (1985) Med. Phys., 12 (2), pp. 232-233
Haralick, R. M., Dinstein, I. H., Textural features for image classification (1973) IEEE Trans. Syst. Man Cybern., 3 (6), pp. 610-621. , SMC
Da, A. A. J. R., Quantification of histochemical staining by color deconvolution (2001) Anal. Quant. Cytol. Histol., 23 (4), pp. 291-299
J Control Release (ISSN: 0168-3659), 2015 Jan 24; 202: 21-30.
Tipo di articolo: Journal Article,
Impact factor: 7.441, Impact factor a 5 anni: 8.407
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84921957698&partnerID=40&md5=b3ea740a30eba97245ac851bcc56ea81
Parole chiave: Chemotherapy, Drug Products, Fluorescence Microscopy, Medical Nanotechnology, Tumors, Ultrasonic Applications, Antitumor Drugs, Focused Ultrasound, Imaging Agent, Mri Contrasts, Theranostic Agents, Therapeutic Benefits, Therapeutic Outcomes, Translatability, Liposomes, Doxorubicin, Gadoteridol, Animal Cell, Animal Experiment, Animal Model, Article, Breast Cancer, Cancer Cell, Confocal Microscopy, Contrast Enhancement, Contrast To Noise Ratio, Controlled Study, Drug Release, Ex Vivo Study, Female, In Vitro Study, In Vivo Study, Liposomal Delivery, Mouse, Nonhuman, Nuclear Magnetic Resonance Imaging, Priority Journal, Pulsed Low Intensity Non Focused Ultrasound,
Affiliazioni:
*** IBB - CNR ***
Center for Molecular Imaging, Department of Molecular Biotechnology and Health Sciences, University of Torino, Via Nizza 52Torino, Italy
Center for Preclinical Imaging, Department of Molecular Biotechnology and Health Sciences, University of Torino, Via Ribes 5Colleretto Giacosa (TO), Italy
Institute for Biostructures and Bioimages (CNR), C/o Molecular Biotechnology Center, University of Torino, Italy
Biolab, Department of Electronics and Telecommunications, Politecnico di TorinoTorino, Italy
Riferimenti:
Terreno, E., Uggeri, F., Aime, S., Image guided therapy: The advent of theranostic agents (2012) J. Control. Release, 161 (2), pp. 328-33
Prabhu, P., Patravale, V., The upcoming field of theranostic nanomedicine: An overview (2012) J. Biomed. Nanotechnol., 8 (6), pp. 859-882
Sumer, B., Gao, J.M., Theranostic nanomedicine for cancer (2008) Nanomedicine, 3 (2), pp. 137-140
Weissleder, R., Pittet, M.J., Imaging in the era of molecular oncology (2008) Nature, 452 (7187), pp. 580-589
Massoud, T.F., Gambhir, S.S., Molecular imaging in living subjects: Seeing fundamental biological processes in a new light (2003) Genes Dev., 17 (5), pp. 545-580
Weissleder, R., Molecular imaging: Exploring the next frontier (1999) Radiology, 212 (3), pp. 609-614
Jacobs, R.E., Cherry, S.R., Complementary emerging techniques: High-resolution PET and MRI (2001) Curr. Opin. Neurobiol., 11 (5), pp. 621-629
Manzoor, A.A., Overcoming limitations in nanoparticle drug delivery: Triggered, intravascular release to improve drug penetration into tumors (2012) Cancer Res., 72 (21), pp. 5566-5575
Lammers, T., Theranostic nanomedicine (2011) Acc. Chem. Res., 44 (10), pp. 1029-1038
Torchilin, V., Liposomes in drug delivery (2012) Fundamentals and Applications of Controlled Release Drug Delivery, pp. 289-328. , J. Siepmann, R.A. Siegel, M.J. Rathbone, Springer New York
Ponce, A.M., Hyperthermia mediated liposomal drug delivery (2006) Int. J. Hyperth., 22 (3), pp. 205-213
Koning, G.A., Hyperthermia and thermosensitive liposomes for improved delivery of chemotherapeutic drugs to solid tumors (2010) Pharm. Res., 27 (8), pp. 1750-1754
Needham, D., A new temperature-sensitive liposome for use with mild hyperthermia: Characterization and testing in a human tumor xenograft model (2000) Cancer Res., 60 (5), pp. 1197-1201
Torres, E., Improved paramagnetic liposomes for MRI visualization of pH triggered release (2011) J. Control. Release, 154 (2), pp. 196-202
Kuppusamy, P., Noninvasive imaging of tumor redox status and its modification by tissue glutathione levels (2002) Cancer Res., 62 (1), pp. 307-312
Mellal, D., Zumbuehl, A., Exit-strategies - Smart ways to release phospholipid vesicle cargo (2014) J. Mater. Chem. B, 2 (3), pp. 247-252
Zhu, L., Torchilin, V.P., Stimulus-responsive nanopreparations for tumor targeting (2013) Integr. Biol., 5 (1), pp. 96-107
Singh, R., Torti, S.V., Carbon nanotubes in hyperthermia therapy (2013) Adv. Drug Deliv. Rev., 65 (15), pp. 2045-2060
Bazrafshan, B., Temperature imaging of laser-induced thermotherapy (LITT) by MRI: Evaluation of different sequences in phantom (2014) Lasers Med. Sci., 29 (1), pp. 173-183
Kostrzewa, M., Microwave ablation of osteoid osteomas using dynamic MR imaging for early treatment assessment: Preliminary experience (2014) J. Vasc. Interv. Radiol., 25 (1), pp. 106-111
De Smet, M., Magnetic resonance guided high-intensity focused ultrasound mediated hyperthermia improves the intratumoral distribution of temperature-sensitive liposomal doxorubicin (2013) Investig. Radiol., 48 (6), pp. 395-405
Grull, H., Langereis, S., Hyperthermia-triggered drug delivery from temperature-sensitive liposomes using MRI-guided high intensity focused ultrasound (2012) J. Control. Release, 161 (2), pp. 317-327
Negussie, A.H., Formulation and characterisation of magnetic resonance imageable thermally sensitive liposomes for use with magnetic resonance-guided high intensity focused ultrasound (2011) Int. J. Hyperth., 27 (2), pp. 140-155
Ranjan, A., Image-guided drug delivery with magnetic resonance guided high intensity focused ultrasound and temperature sensitive liposomes in a rabbit Vx2 tumor model (2012) J. Control. Release, 158 (3), pp. 487-494
Li, L., Mild hyperthermia triggered doxorubicin release from optimized stealth thermosensitive liposomes improves intratumoral drug delivery and efficacy (2013) J. Control. Release, 168 (2), pp. 142-150
Lanza, G.M., Assessing the barriers to image-guided drug delivery (2014) Wiley Interdiscip. Rev. Nanomed. Nanobiotechnol., 6 (1), pp. 1-14
Fernando, R., MRI-guided monitoring of thermal dose and targeted drug delivery for cancer therapy (2013) Pharm. Res., 30 (11), pp. 2709-2717
Dewhirst, M.W., Novel Approaches to Treatment of Hepatocellular Carcinoma and Hepatic Metastases Using Thermal Ablation and Thermosensitive Liposomes (2013) Surgical Oncology Clinics of North America, 22 (3), pp. 545-561
McDaniel, J.R., Dewhirst, M.W., Chilkoti, A., Actively targeting solid tumours with thermoresponsive drug delivery systems that respond to mild hyperthermia (2013) Int. J. Hyperth., 29 (6), pp. 501-510
Sharma, D., Chelvi, T.P., Ralhan, R., Thermosensitive liposomal taxol formulation: Heat-mediated targeted drug delivery in murine melanoma (1998) Melanoma Res., 8 (3), pp. 240-244
Papahadjopoulos, D., Phase transitions in phospholipid vesicles. Fluorescence polarization and permeability measurements concerning the effect of temperature and cholesterol (1973) Biochim. Biophys. Acta, 311 (3), pp. 330-348
Dicheva, B.M., Koning, G.A., Targeted thermosensitive liposomes: An attractive novel approach for increased drug delivery to solid tumors (2014) Expert Opin. Drug Deliv., 11 (1), pp. 83-100
Li, L., A novel two-step mild hyperthermia for advanced liposomal chemotherapy (2014) J. Control. Release, 174, pp. 202-208
Nakayama, M., Akimoto, J., Okano, T., Polymeric micelles with stimuli-triggering systems for advanced cancer drug targeting (2014) J. Drug Target., 22 (7), pp. 584-599
May, J.P., Li, S.D., Hyperthermia-induced drug targeting (2013) Expert Opin. Drug Deliv., 10 (4), pp. 511-527
Needham, D., Materials characterization of the low temperature sensitive liposome (LTSL): Effects of the lipid composition (lysolipid and DSPE-PEG2000) on the thermal transition and release of doxorubicin (2013) Faraday Discuss., 161, pp. 515-534
Langereis, S., Paramagnetic liposomes for molecular MRI and MRI-guided drug delivery (2013) NMR Biomed., 26 (7), pp. 728-744
Wang, S., Pulsed high intensity focused ultrasound increases penetration and therapeutic efficacy of monoclonal antibodies in murine xenograft tumors (2012) J. Control. Release, 162 (1), pp. 218-224
Chen, X.Y., Gambhlr, S.S., Cheon, J., Theranostic nanomedicine (2011) Acc. Chem. Res., 44 (10). , p. 841
Lin, C.Y., Ultrasound sensitive eLiposomes containing doxorubicin for drug targeting therapy (2014) Nanomedicine, 10 (1), pp. 67-76
Lin, H.Y., Thomas, J.L., Factors affecting responsivity of unilamellar liposomes to 20 kHz ultrasound (2004) Langmuir, 20 (15), pp. 6100-6106
Evjen, T.J., In vivo monitoring of liposomal release in tumours following ultrasound stimulation (2013) Eur. J. Pharm. Biopharm., 84 (3), pp. 526-531
Giustetto, P., Release of a paramagnetic magnetic resonance imaging agent from liposomes triggered by low intensity non-focused ultrasound (2013) J. Med. Imaging Health Inform., 3 (3), pp. 356-366
Datta, S., Correlation of cavitation with ultrasound enhancement of thrombolysis (2006) Ultrasound Med. Biol., 32 (8), pp. 1257-1267
Schroeder, A., Kost, J., Barenholz, Y., Ultrasound, liposomes, and drug delivery: Principles for using ultrasound to control the release of drugs from liposomes (2009) Chem. Phys. Lipids, 162 (12), pp. 1-16
Yudina, A., Ultrasound-mediated intracellular drug delivery using microbubbles and temperature-sensitive liposomes (2011) J. Control. Release, 155 (3), pp. 442-448
Schroeder, A., Controlling liposomal drug release with low frequency ultrasound: Mechanism and feasibility (2007) Langmuir, 23 (7), pp. 4019-4025
Afadzi, M., Mechanisms of the ultrasound-mediated intracellular delivery of liposomes and dextrans (2013) IEEE Trans. Ultrason. Ferroelectr. Freq. Control, 60 (1), pp. 21-33
Staples, B.J., Role of frequency and mechanical index in ultrasonic-enhanced chemotherapy in rats (2009) Cancer Chemother. Pharmacol., 64 (3), pp. 593-600
Knodler, M., An analysis of toxicity in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck (R/M SCCHN) receiving cetuximab, fluorouracil and cisplatin alone or with docetaxel in a phase II clinical trial (CeFCiD) (2012) Onkologie, 35, p. 153
Fattahi, H., Magnetoliposomes as multimodal contrast agents for molecular imaging and cancer nanotheragnostics (2011) Nanomedicine, 6 (3), pp. 529-544
Aime, S., Pushing the sensitivity envelope of lanthanide-based magnetic resonance imaging (MRI) contrast agents for molecular imaging applications (2009) Acc. Chem. Res., 42 (7), pp. 822-831
Terreno, E., Paramagnetic liposomes as innovative contrast agents for magnetic resonance (MR) molecular imaging applications (2008) Chem. Biodivers., 5 (10), pp. 1901-1912
Fossheim, S.L., Paramagnetic liposomes as MRI contrast agents: Influence of liposomal physicochemical properties on the in vitro relaxivity (1999) Magn. Reson. Imaging, 17 (1), pp. 83-89
Castelli, D.D., Metal containing nanosized systems for MR-molecular imaging applications (2008) Coord. Chem. Rev., 252 (2122), pp. 2424-2443
Rizzitelli, S., Giustetto, P., Boffa, C., Delli Castelli, D., Cutrin, J.C., Aime, S., Terreno, E., In vivo MRI visualization of release from liposomes triggered by local application of pulsed low intensity non focused ultrasound (2014) Nanomedicine, 10 (5), pp. 901-904
Barge, A., How to determine free Gd and free ligand in solution of Gd chelates. A technical note (2006) Contrast Media Mol. Imaging, 1 (5), pp. 184-188
Nanni, P., TS/A: A new metastasizing cell line from a BALB/c spontaneous mammary adenocarcinoma (1983) Clin. Exp. Metastasis, 1 (4), pp. 373-380
Steckner, M.C., Liu, B., Ying, L., A new single acquisition, two-image difference method for determining MR image SNR (2009) Med. Phys., 36 (2), pp. 662-671
Dietrich, O., Measurement of signal-to-noise ratios in MR images: Influence of multichannel coils, parallel imaging, and reconstruction filters (2007) J. Magn. Reson. Imaging, 26 (2), pp. 375-385
Henkelman, R.M., Measurement of signal intensities in the presence of noise in mr images (1985) Med. Phys., 12 (2), pp. 232-233
Castellano, G., Li, L.M., Cendes, F., Texture analysis of medical images (2004) Clin. Radiol., 59 (12), pp. 1061-1069
Haralick, R.M., Dinstein, I.H., Textural features for image classification (1973) IEEE Trans. Syst. Man Cybern., 3 (6), pp. 610-621. , SMC
Da, A.A.J.R., Quantification of histochemical staining by color deconvolution (2001) Anal. Quant. Cytol. Histol., 23 (4), pp. 291-299
Sumer, B., Gao, J. M., Theranostic nanomedicine for cancer (2008) Nanomedicine, 3 (2), pp. 137-140
Massoud, T. F., Gambhir, S. S., Molecular imaging in living subjects: Seeing fundamental biological processes in a new light (2003) Genes Dev., 17 (5), pp. 545-580
Jacobs, R. E., Cherry, S. R., Complementary emerging techniques: High-resolution PET and MRI (2001) Curr. Opin. Neurobiol., 11 (5), pp. 621-629
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The main goal of this study was to assess the theranostic performance of a nanomedicine able to generate MRI contrast as a response to the release from liposomes of the antitumor drug Doxorubicin triggered by the local exposure to pulsed low intensity non focused ultrasounds (pLINFU). In vitro experiments showed that Gadoteridol was an excellent imaging agent for probing the release of Doxorubicin following pLINFU stimulation. On this basis, the theranostic system was investigated in vivo on a syngeneic murine model of TS/A breast cancer. MRI offered an excellent guidance for monitoring the pLINFU-stimulated release of the drug. Moreover, it provided: i) an in vivo proof of the effective release of the liposomal content, and ii) a confirmation of the therapeutic benefits of the overall protocol. Ex vivo fluorescence microscopy indicated that the good therapeutic outcome was originated from a better diffusion of the drug in the tumor following the pLINFU stimulus. Very interestingly, the broad diffusion of the drug in the tumor stroma appeared to be mediated by the presence of the liposomes themselves. The results of this study highlighted either the great potential of US-based stimuli to safely trigger the release of a drug from its nanocarrier or the associated significant therapeutic improvement. Finally, MRI demonstrated to be a valuable technique to support chemotherapy and monitoring the outcome. Furthermore, in this specific case, the theranostic agent developed has a high clinical translatability because the MRI agent utilized is already approved for human use. © 2015 Elsevier B.V. All rights reserved.
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Zaccaro L, Del Gatto A, Pedone C, Saviano M
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Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2009 Mar; 16(7): 780-795.
Impact Factor: 4.708
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Salvatore B, Simeone R, Fonti R, Marciano R, Bianco R, Damiano V, Tortora G, Pace L, Del Vecchio S, Salvatore M
* 18F-FDG PET/CT in the assessment of early response to chemotherapy and molecularly targeted agents in metastatic colorectal cancer (167 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2008 Oct; 35: N/D-N/D.
Impact Factor: 4.532
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Cirioni O, Ghiselli R, Orlando F, Silvestri C, De Luca S, Salzano AM, Mocchegiani F, Saba V, Scalise G, Scaloni A, Giacometti A
* Efficacy of the amphibian peptide distinctin in a neutropenic mouse model of staphylococcal sepsis (185 visite)
Critical Care Medicine (ISSN: 0090-3493), 2008 Sep; 36(9): 2629-2633.
Impact Factor: 6.594
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Picardi M, De Renzo A, Pane F, Nicolai E, Pacelli R, Salvatore M, Rotoli B
* Randomized comparison of consolidation radiation versus observation in bulky Hodgkin's lymphoma with post-chemotherapy negative positron emission tomography scans (264 visite)
Leuk Lymphoma (ISSN: 1042-8194, 1026-8022linking), 2007 Sep; 48(9): 1721-1727.
Impact Factor: 1.512
Dettagli Esporta in BibTeX Esporta in EndNote
Del Vecchio S, Zannetti A, Fonti R, Pace L, Salvatore M
* Nuclear imaging in cancer theranostics (449 visite)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2007 Jun; 51(2): 152-163.
Impact Factor: 1.724
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De Renzo A, Perna F, Persico M, Mainolfi C, Pace L
* 18F-fluorodeoxyglucose positron emission tomography/computed tomography in the evaluation of early response in a primary hepatic lymphoma (166 visite)
Br J Haematol (ISSN: 0007-1048, 0007-1048linking, 1365-2141electronic), 2006 Jun; 133(6): 580-580.
Impact Factor: 4.498
Dettagli Esporta in BibTeX Esporta in EndNote
Pace L, Catalano L, Del Vecchio S, De Renzo A, Fonti R, Salvatore B, Andretta C, Di Nuzzo C, Rotoli B, Salvatore M
* Washout of [99mTc] sestamibi in predicting response to chemotherapy in patients with multiple myeloma (222 visite)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2005 Sep; 49(3): 281-285.
Impact Factor: 1.724
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Merlino A, Mazzarella L, Carannante A, Di Fiore A, Di Donato A, Notomista E, Sica F
* The importance of dynamic effects on the enzyme activity: X-ray structure and molecular dynamics of onconase mutants (320 visite)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2005 May 6; 280(18): 17953-17960.
Impact Factor: 5.854
Dettagli Esporta in BibTeX Esporta in EndNote
Tauchmanovà L, Pensabene M, Capuano I, Spagnoletti I, Zeppa P, Del Vecchio S, Mainenti PP, De Rosa G, Colao A, Contegiacomo A
* Poorly differentiated small cell neuroendocrine carcinoma localized in three different endocrine glands: Response to chemotherapy and octreotide LAR (252 visite)
J Endocrinol Invest (ISSN: 0391-4097, 1720-8386electronic), 2005 Apr; 28(4): 371-378.
Impact Factor: 1.496
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d'Alesio V, Pacelli R, Durante M, Canale Cama G, Cella L, Gialanella G, Grossi G, Pugliese M, Punzo G, Sardi I, Scampoli P, Solla R, Salvatore M
* Lymph nodes in the irradiated field influence the yield of radiation-induced chromosomal aberrations in lymphocytes from breast cancer patients (228 visite)
Int J Radiat Oncol (ISSN: 0360-3016, 1879-355x, 1879-355xelectronic), 2003 Nov 1; 57(3): 732-738.
Impact Factor: 4.285
Dettagli Esporta in BibTeX Esporta in EndNote
Mainenti PP, Romano L, Contegiacomo A, Romano M, Casella V, Cuccuru A, Insabato L, Salvatore M
* Rare diffuse peritoneal malignant neoplasms: CT findings in two cases (184 visite)
Abdom Imaging (ISSN: 0942-8925, 1432-0509), 2003 Nov; 28(6): 827-830.
Impact Factor: 0.996
Dettagli Esporta in BibTeX Esporta in EndNote
Del Vecchio S, Zannetti A, Aloj L, Caracò C, Ciarmiello A, Salvatore M
* Inhibition of early Tc-99m-MIBI uptake by Bcl-2 anti-apoptotic protein overexpression in untreated breast carcinoma (379 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2003 Jun; 30(6): 879-887.
Impact Factor: 3.324
Dettagli Esporta in BibTeX Esporta in EndNote
Del Vecchio S, Zannetti A, Aloj L, Salvatore M
* MIBI as prognostic factor in breast cancer (310 visite)
Q J Nucl Med (ISSN: 1124-3937, 1125-0135), 2003 Mar; 47(1): 46-50.
Impact Factor: 2.222
Dettagli Esporta in BibTeX Esporta in EndNote
Acampa W, Petretta M, Cuocolo A
* Nuclear medicine procedures in cardiovascular diseases: An evidence based approach (348 visite)
Q J Nucl Med (ISSN: 1124-3937, 1125-0135), 2002 Dec; 46(4): 323-330.
Impact Factor: 1.903
Dettagli Esporta in BibTeX Esporta in EndNote
Monfrecola G, Procaccini EM, D'Onofrio D, Roberti G, Liuzzi R, Staibano S, Manco A, De Rosa G, Santoianni P
* Hyperpigmentation induced by topical 5-aminolaevulinic acid plus visible light (228 visite)
J Photochem Photobiol B (ISSN: 1011-1344, 1011-1344print, 1011-1344linking), 2002 Nov; 68(2-3): 147-155.
Impact Factor: 1.573
Dettagli Esporta in BibTeX Esporta in EndNote
Aloj L, Panico M, Caracó C, Zannetti A, Del Vecchio S, Di Nuzzo C, Arra C, Morelli G, Tesauro D, De Luca S, Pedone C, Salvatore M
* Radiolabeling approaches for cholecystokinin B receptor imaging (398 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2002; 66(6): 370-380.
Impact Factor: 2.372
Dettagli Esporta in BibTeX Esporta in EndNote
Danforth Dn JR, Aloj L, Carrasquillo JA, Bacharach SL, Chow C, Zujewski J, Whatley M, Galen B, Merino M, Neumann RD
* The role of 18F-FDG-PET in the local/regional evaluation of women with breast cancer (202 visite)
Breast Cancer Res Tr Kluwer Academic Publishers (ISSN: 0167-6806), 2002; 75(2): 135-146.
Impact Factor: 3.132
Dettagli Esporta in BibTeX Esporta in EndNote
Pace L, Catalano L, Del Vecchio S, De Renzo A, Fonti R, Sica G, Annunziata G, Califano C, Rotoli B, Salvatore M
* Wash-out of 99mTc-sestamibi (99mTc-MIBI) in evaluating response to chemotherapy in patients with multiple myeloma (MM) (222 visite)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 2001 Sep; 28(8): N/D-N/D.
Impact Factor: 3.464
Dettagli Esporta in BibTeX Esporta in EndNote
Pace L, Catalano L, Del Vecchio S, Di Gennaro F, De Renzo A, Sica G, Califano C, Tedesco N, Borrelli G, Rotoli B, Salvatore M
* Predictive value of technetium-99m sestamibi in patients with multiple myeloma and potential role in the follow-up (246 visite)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 2001 Mar; 28(3): 304-312.
Impact Factor: 3.464
Dettagli Esporta in BibTeX Esporta in EndNote
Gridelli C, Manzione L, Perrone F, Veltri E, Cioffi R, Caprio MG, Frontini L, Rossi A, Barletta E, Barzelloni ML, Bilancia D, Gallo C
* Carboplatin plus paclitaxel in extensive small cell lung cancer: a multicentre phase 2 study (158 visite) (PDF 194 visite)
Br J Cancer (ISSN: 0007-0920print, 0007-0920linking), 2001 Jan 5; 84(1): 38-41.
Impact Factor: 3.942
Dettagli Esporta in BibTeX Esporta in EndNote
Colasanti A, Kisslinger A, Liuzzi R, Quarto M, Riccio P, Roberti G, Tramontano D, Villani F
Hypericin photosensitization of tumor and metastatic cell lines of human prostate (177 visite)
J Photochem Photobiol B (ISSN: 1011-1344print, 1011-1344linking), 2000 Feb; 54(2-3): 103-107.
Impact Factor: 1.529
Dettagli Esporta in BibTeX Esporta in EndNote
Lombardi A, De Simone G, Galdiero S, Staiano N, Nastri F, Pavone V
From natural to synthetic multisite thrombin inhibitors (198 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1999; 51(1): 19-39.
Impact Factor: 2.331
Dettagli Esporta in BibTeX Esporta in EndNote
Imbriaco M, De Iuri A, Camera L
Isolated uterine relapse in a child with acute lymphoblastic leukemia (153 visite)
Ajr Am J Roentgenol (ISSN: 0361-803x), 1998 Oct; 171(4): 1166-1167.
Impact Factor: 2.179
Dettagli Esporta in BibTeX Esporta in EndNote
Ciarmiello A, Del Vecchio S, Silvestro P, Potena MI, Carriero MV, Thomas R, Botti G, D'Aiuto G, Salvatore M
Tumor clearance of technetium 99m-sestamibi as a predictor of response to neoadjuvant chemotherapy for locally advanced breast cancer (234 visite)
Journal Of Clinical Oncology (ISSN: 0732-183x), 1998 May; 16(5): 1677-1683.
Impact Factor: 8.228
Dettagli Esporta in BibTeX Esporta in EndNote
MAUREA S, LASTORIA S, CARACO C, INDOLFI P, CASALE F, DITULLIO M, SALVATORE M
IODINE-131-MIBG IMAGING TO MONITOR CHEMOTHERAPY RESPONSE IN ADVANCED NEUROBLASTOMA - COMPARISON WITH LABORATORY ANALYSIS (219 visite)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1994 Sep; 35(9): 1429-1435.
Impact Factor: 3.491
Dettagli Esporta in BibTeX Esporta in EndNote
Gurrieri S, Rizzarelli E, Beach D, Bustamante C
Imaging of kinked configurations of DNA molecules undergoing orthogonal field alternating gel electrophoresis by fluorescence microscopy (444 visite)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 1990 Apr 3; 29(13): 3396-3401.
Impact Factor: 4.572
Dettagli Esporta in BibTeX Esporta in EndNote
Iaffaioli RV, Frasci G, Di Tuoro AS, Facchini G, Pacelli R, Scala S, Fasolino A, Bianco AR
Malignant lymphoma of the ovary: report on two cases and review of the literature (230 visite)
Eur J Gynaecol Oncol (ISSN: 0392-2936), 1990; 11(3): 205-208.
Impact Factor: 0.397
Dettagli Esporta in BibTeX Esporta in EndNote
Iaffaioli RV, Frasci G, Tortora G, Ciardiello F, Nuzzo F, Scala S, Pacelli R, Bianco AR
Effect of thymic extract 'thymostimulin' on the incidence of infections and myelotoxicity during adjuvant chemotherapy for breast cancer (400 visite)
Thymus (ISSN: 0165-6090), 1988; 12(2): 69-75.
Impact Factor: 0.643
Dettagli Esporta in BibTeX Esporta in EndNote
73 Records (69 escludendo Abstract e Conferenze).
Impact factor totale: 317.947 (301.042 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 337.768 (318.93 escludendo Abstract e Conferenze).
Impact factor totale: 317.947 (301.042 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 337.768 (318.93 escludendo Abstract e Conferenze).
Esporta in BibTeX Esporta in EndNote
Ultima modifica di Marco Comerci in data Sunday 12 July 2020, 13:14:49
327 visite. Ultima visita in data Sunday 06 September 2020, 11:09:45
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