REVERSE REDISTRIBUTION IN RESTING TL-201 MYOCARDIAL SCINTIGRAPHY IN CHRONIC CORONARY-ARTERY DISEASE - AN INDEX OF MYOCARDIAL VIABILITY(99 visite) PACE L, CUOCOLO A, MARZULLO P, NICOLAI E, GIMELLI A, DELUCA N, RICCIARDELLI B, SALVATORE M
Tipo di articolo: Journal Article, Abstract, Conference,
Impact factor: 3.491, Impact factor a 5 anni: 5.331
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The aim of this study was to evaluate whether segments with reverse redistribution on rest-redistribution (TI)-T-201 scintigraphy represent viable tissue or scar. Methods: Nineteen patients (17 men, 2 women; mean age 53 +/- 8 yr) with coronary artery disease underwent rest-redistribution (TI)-T-201 study before coronary revascularization. Regional (TI)-T-201 uptake was analyzed quantitatively. Regional left ventricular wall motion was assessed before and after coronary revascularization using two-dimensional echocardiography and a three-point scale (1 = normal, 2 = hypokinetic, 3 = akinetic/dyskinetic). Two patterns of reverse redistribution were identified: pattern with normal (TI)-T-201 uptake in rest and abnormal in redistribution images and pattern with abnormal (TI)-T-201 uptake in rest and a significant decrease in redistribution images. Results: Of the 247 segments analyzed, 85 were classified as normal, 37 as reversible defects, 83 as fixed defects and 42 as reverse redistribution (19 RR-A, 23 RR-B). Segments with RR-A differed from those with RR-B in wall motion score (1.4 +/- 0.7 versus 2.0 +/- 1.0). Electrocardiographic Q-waves were present in 26% of segments with RR-A and in 57% of segments with pattern B. After revascularization, all dyssynergic segments with pattern A showed improved wall motion, while only 40% of segments with pattern B and abnormal wall motion had such improvement. Conclusion: Our results suggest that dyssynergic segments with pattern A should be considered viable, while more caution should be used in classifying those with pattern B.
329 Records (259 escludendo Abstract e Conferenze). Impact factor totale: 981.498 (694.496 escludendo Abstract e Conferenze). Impact factor a 5 anni totale: 1093.804 (767.095 escludendo Abstract e Conferenze).
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