Diabetes in a geriatric ward: Efficacy and safety of new insulin analogs in very old inpatients(111 visite) Franchin A, Corradin ML, Giantin V, Rossi F, Zanatta F, Attanasio F, Toffanello ED, Manzato E
Parole chiave: Diabetes Prevalence, Elderly Diabetic Inpatients, Insulin Analogs, Insulin Derivative, Long Acting Insulin, Short Acting Insulin, Aged, Article, Diabetes Mellitus, Drug Efficacy, Drug Safety, Geriatrics, Glycemic Control, Hospital Patient, Hospitalization, Human, Hyperglycemia, Hypoglycemia, Insulin Treatment, Major Clinical Study, Medical Record Review, Mortality, Observational Study, Outcome Assessment, Retrospective Study, Age Factors, 80 And Over, Health Services For The Aged, Hypoglycemic Agents, Retrospective Studies,
Affiliazioni:
*** IBB - CNR *** Geriatric Unit, Department of Medicine, University of Padova Hospital, Via Giustiniani 2, 35128 Padova, Italy
Riferimenti:
Tanwani, L.K., Insulin therapy in the elderly patient with diabetes (2011) Am J Geriatr Pharmacother, 9, pp. 24-3
Umpierrez, G.E., Isaacs, S.D., Bazargan, N., You, X., Thaler, L.M., Kitabchi, A.E., Hyperglycemia: An independent marker of in-hospital mortality in patients with undiagnosed diabetes (2002) J Clin Endocrinol Metab, 87, pp. 978-982
Clement, S., Braithwaite, S.S., Magee, M.F., Management of diabetes and hyperglycemia in hospitals (2004) Diabetes Care, 27, pp. 553-591
Wexler, D.J., Nathan, D.M., Grant, R.W., Regan, S., Van Leuvan, A.L., Cagliero, E., Prevalence of elevated haemoglobin A1c among patients admitted to the hospital without a diagnosis of diabetes (2008) J Clin Endocrinol Metab, 93, pp. 4238-4244
Garber, A.J., Moghissi, E.S., Bransome Jr., E.D., American college of endocrinology position statement on inpatient diabetes and metabolic control (2004) Endocr Pract, 10, pp. 77-82
Yang, Y., Goh, S.Y., Tan, S.B., The burden of diabetes mellitus in elderly patients from an asian tertiary hospital (2012) Eur J Intern Med, 23, pp. e1-4
Sloan, F.A., Bethel, M.A., Ruiz Jr., D., Shea, A.M., Feinglos, M.N., The growing burden of diabetes mellitus in the US elderly population (2008) Arch Intern Med, 168, pp. 192-199
Standards of medical care in diabetes - 2012 (2012) Diabetes Care, 35 (SUPPL. 1), pp. S11-63. , American Diabetes Association
Heller, S., McCance, D.R., Moghissi, E., Nazeri, A., Kordonouri, O., Diversity in diabetes: The role of insulin aspart (2012) Diabetes Metab Res Rev, 28, pp. 50-61
Lecomte, P., Diabetes in the elderly: Considerations for clinical practice (2005) Diabetes Metab, 31 (SPEC. NO 2), pp. 5S105-11
(2011) National Diabetes Information Clearinghouse (NDIC): National Diabetes Statistics, , http://diabetes.niddk.nih.gov/dm/pubs/statistics/, Accessed September 19, 2012
Suh, D.C., Kim, C.M., Choi, I.S., Plauschinat, C.A., Comorbid conditions and glycemic control in elderly patients with type 2 diabetes mellitus, 1988 to 1994 to 1999 to 2004 (2008) J Am Geriatr Soc, 56, pp. 484-492
Cryer, P.E., Hypoglycaemia: The limiting factor in the glycaemic management of type i and type II diabetes (2002) Diabetologia, 45, pp. 937-948
Umpierrez, G.E., Hellman, R., Korytkowski, M.T., Management of hyperglycemia in hospitalized patients in non-critical care setting: An Endocrine Society Clinical Practice Guideline (2012) J Clin Endocrinol Metab, 97, pp. 16-38
Hirsch, I.B., Insulin analogues (2005) N Engl J Med, 352, pp. 174-183
Tanwani, L. K., Insulin therapy in the elderly patient with diabetes (2011) Am J Geriatr Pharmacother, 9, pp. 24-3
Umpierrez, G. E., Isaacs, S. D., Bazargan, N., You, X., Thaler, L. M., Kitabchi, A. E., Hyperglycemia: An independent marker of in-hospital mortality in patients with undiagnosed diabetes (2002) J Clin Endocrinol Metab, 87, pp. 978-982
Wexler, D. J., Nathan, D. M., Grant, R. W., Regan, S., Van Leuvan, A. L., Cagliero, E., Prevalence of elevated haemoglobin A1c among patients admitted to the hospital without a diagnosis of diabetes (2008) J Clin Endocrinol Metab, 93, pp. 4238-4244
Garber, A. J., Moghissi, E. S., Bransome Jr., E. D., American college of endocrinology position statement on inpatient diabetes and metabolic control (2004) Endocr Pract, 10, pp. 77-82
Yang, Y., Goh, S. Y., Tan, S. B., The burden of diabetes mellitus in elderly patients from an asian tertiary hospital (2012) Eur J Intern Med, 23, pp. e1-4
Sloan, F. A., Bethel, M. A., Ruiz Jr., D., Shea, A. M., Feinglos, M. N., The growing burden of diabetes mellitus in the US elderly population (2008) Arch Intern Med, 168, pp. 192-199
(2011) National Diabetes Information Clearinghouse (NDIC): National Diabetes Statistics, , http: //diabetes. niddk. nih. gov/dm/pubs/statistics/, Accessed September 19, 2012
Suh, D. C., Kim, C. M., Choi, I. S., Plauschinat, C. A., Comorbid conditions and glycemic control in elderly patients with type 2 diabetes mellitus, 1988 to 1994 to 1999 to 2004 (2008) J Am Geriatr Soc, 56, pp. 484-492
Cryer, P. E., Hypoglycaemia: The limiting factor in the glycaemic management of type i and type II diabetes (2002) Diabetologia, 45, pp. 937-948
Umpierrez, G. E., Hellman, R., Korytkowski, M. T., Management of hyperglycemia in hospitalized patients in non-critical care setting: An Endocrine Society Clinical Practice Guideline (2012) J Clin Endocrinol Metab, 97, pp. 16-38
Hirsch, I. B., Insulin analogues (2005) N Engl J Med, 352, pp. 174-183
Aims: 1) to evaluate the prevalence of diabetes mellitus (DM) in a geriatric ward; 2) to assess the efficacy and safety of insulin analogs in elderly inpatients over 65 years of age. Methods: We analysed the medical records of 1851 elderly inpatients admitted to our geriatric clinic from March 2009 to September 2011, to identify patients with DM. The efficacy and safety of insulin analogs were measured in patients with a hospital stay of at least 9 days, by assessing the means of all glycemic sticks (4-7 sticks/day), number of hyperglycemic events (>250 mg/dL) and number of hypoglycemic events (
Petraglia F, Singh AA, Carafa V, Nebbioso A, Conte M, Scisciola L, Valente S, Baldi A, Mandoli A, Petrizzi VB, Ingenito C, De Falco S, Cicatiello V, Apicella I, Janssen-megens EM, Kim B, Yi G, Logie C, Heath S, Ruvo M, Wierenga ATJ, Flicek P, Yaspo ML, Della Valle V, Bernard O, Tomassi S, Novellino E, Feoli A, Sbardella G, Gut I, Vellenga E, Stunnenberg HG, Mai A, Martens JHA, Altucci L * Combined HAT/EZH2 modulation leads to cancer-selective cell death(47 visite) Oncotarget (ISSN: 1949-2553electronic, 1949-2553linking), 2018 May 22; 9(39): 25630-25646. Impact Factor:5.008 DettagliEsporta in BibTeXEsporta in EndNote
157 Records (132 escludendo Abstract e Conferenze). Impact factor totale: 613.854 (507.947 escludendo Abstract e Conferenze). Impact factor a 5 anni totale: 632.872 (519.282 escludendo Abstract e Conferenze).
ibb.cnr.it