Interactions of gold-based drugs with proteins: crystal structure of the adduct formed between ribonuclease A and a cytotoxic gold(III) compound (172 visite)
Metallomics (ISSN: 1756-5901, 1756-591x), 2014; 6(2): 233-236.
Tipo di articolo: Journal Article,
Impact factor: 3.585, Impact factor a 5 anni: 3.98
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84893276097&partnerID=40&md5=6ba50ce6078b2777e720fe9dcdca3ca6
Parole chiave: Adduct Formation, Bovine Pancreatic Ribonuclease, Cytotoxic, Dinuclear, Esi Mass Spectrometry, Mode Of Action, Model Proteins, X Ray Diffraction, Gold, Auoxo6, Auranofin, Gold Complex, Histidine, Ligand, Metallodrug, Peroxiredoxin, Prodrug, Thioredoxin Reductase, Unclassified Drug, Antineoplastic Activity, Cattle, Chemical Structure, Complex Formation, Conference Paper, Crystal Structure, Electrospray Mass Spectrometry, Enzyme Activity, Nonhuman, Priority Journal, Animals, Cell Death, Crystallography, X-Ray, Hydrolysis, Molecular, Saccharomyces Cerevisiae, Electrospray Ionization,
Affiliazioni:
*** IBB - CNR ***
Department of Chemistry Ugo Schiff, Via della Lastruccia 3, 50019 Sesto Fiorentino (FI), Italy
Department of Chemical Sciences, University of Naples Federico II, Complesso Universitario di Monte sant'Angelo, Via Cintia I-80126, Napoli, Italy
CNR Institute of Biostructures and Bioimages, Napoli, Italy
Riferimenti:
Sun, R.W.-Y., Lok, C.-N., Fong, T.T.-H., Li, C.K.-L., Yang, Z.F., Zou, T., Siu, A.F.-M., Che, C.-M., (2013) Chem. Sci., 4, p. 197
Zhang, J.-J., Sun, R.W.-Y., Che, C.-M., (2012) Chem. Commun., 48, p. 3388
Zhang, J.-J., Lu, W., Sun, R.W.-Y., Che, C.-M., (2012) Angew. Chem., Int. Ed., 51, p. 4882
Yan, J.J., Chow, A.L.-F., Leung, C.H., Sun, R.W.-Y., Ma, D.L., Che, C.-M., (2010) Chem. Commun., 46, p. 3893
Li, C.K.-L., Sun, R.W.-Y., Kui, S.C.-F., Zhu, N., Che, C.-M., (2006) Chem.-Eur. J., 12, p. 5253
Nobili, S., Mini, E., Landini, I., Gabbiani, C., Casini, A., Messori, L., (2010) Med. Res. Rev., 30, p. 550
Barnes, K.R., Lippard, S.J., (2004) Metal Ions Biol. Syst., Cisplatin and Related Anticancer Drugs: Recent Advances and Insights, 42, pp. 43-77. , ed. A. Sigel and H. Sigel, Marcel Dekker Inc., New York Basel Netherlands
Sun, R.W.-Y., Li, C.K.-L., Ma, D.-L., Yan, J.J., Lock, C.-N., Leung, C.-H., Zhu, N., Che, C.-M., (2010) Chem.-Eur. J., 16, p. 3097
Chow, K.H.-M., Sun, R.W.-Y., Lam, J.B.B., Li, C.K.-L., Xu, A., Ma, D.-L., Abagyan, R., Che, C.-M., (2010) Cancer Res., 70, p. 329
Lum, C.T., Yang, Z.F., Li, H.J., Sun, R.W.-Y., Fan, S.T., Poon, R.T., Lin, M.C.M., Kung, H.F., (2006) Int. J. Cancer, 118, p. 1527
Wang, Y., He, Q.Y., Sun, R.W.-Y., Che, C.-M., Chiu, J.F., (2005) Cancer Res., 65, p. 11553
Che, C.-M., Sun, R.W.-Y., Yu, W.-Y., Ko, C.-B., Zhu, N., Sun, H., (2003) Chem. Commun., p. 1718
Cattaruzza, L., Fregona, D., Mongiat, M., Ronconi, L., Fassina, A., Colombatti, A., Aldinucci, D., (2011) Int. J. Cancer, 128, p. 206
Milacic, V., Chen, D., Ronconi, L., Landis-Piwowar, K.R., Fregona, D., Dou, Q.P., (2006) Cancer Res., 66, p. 10478
Ronconi, L., Giovagnini, L., Marzano, C., Bettio, F., Graziani, R., Pilloni, G., Fregona, D., (2005) Inorg. Chem., 44, p. 1867
Giovagnini, L., Ronconi, L., Aldinucci, D., Lorenzon, D., Sitran, S., Fregona, D., (2005) J. Med. Chem., 48, p. 1588
De Vos, D., Ho, S.Y., Tiekink, E.R., (2004) Bioinorg. Chem. Appl., 2, p. 141
Zhang, C.X., Lippard, S.J., (2003) Curr. Opin. Chem. Biol., 7, p. 481
Rosenberg, B., Van Camp, L., Trosko, J.E., Mansour, V.H., (1969) Nature, 222, p. 385
Zou, J., Taylor, P., Dornan, J., Robinson, S.P., Walkinshaw, M.D., Sadler, P.J., (2000) Angew. Chem., Int. Ed., 39, pp. 2931-2934
Urig, S., Fritz-Wolf, K., Réau, R., Herold-Mende, C., Tóth, K., Davioud-Charvet, E., Becker, K., (2006) Angew. Chem., Int. Ed., 45, p. 1881
Bhabak, K.P., Bhuyan, B.J., Mugesh, G., (2011) Dalton Trans., 40, p. 2099
Richards, F.M., Wyckoff, H.W., (1971) The Enzymes, 4, pp. 647-806. , ed. D. Boyer, Academic Press, San Diego
Raines, R.T., (1998) Chem. Rev., 98, p. 1045
Marshal, G.R., Fengand, J.A., Kuster, D.J., (2008) Biopolymers, 90, p. 259
D'Alessio, G., Riordan, J.F., (1997) Ribonucleases. Structures and Functions, , Academic Press, New York
Gutte, B., Merryfield, R.B., (1971) J. Biol. Chem., 246, p. 1922
Kartha, G., Bello, J., Harker, D., (1967) Nature, 213, p. 862
Merlino, A., Sica, F., Mazzarella, L., (2007) J. Phys. Chem., 111, p. 5483
Balakrishnan, R., Ramasubbu, N., Varughese, K.I., Parthasarathy, R., (1997) Proc. Natl. Acad. Sci. U. S. A., 94, p. 9620
Vergara, A., Montesarchio, D., Russo Krauss, I., Paduano, L., Merlino, A., (2013) Inorg. Chem., 52, p. 10714
Isab, A.A., Sadler, P.J., (1977) Biochim. Biophys. Acta, 492, p. 322
Maruyama, T., Sonokawa, S., Matsushita, H., Goto, M., (2007) J. Inorg. Biochem, 101, p. 180
Vitagliano, L., Merlino, A., Zagari, A., Mazzarella, L., (2000) Protein Sci., 9, p. 1217
Casini, A., Cinellu, M.A., Minghetti, G., Gabbiani, C., Coronnello, M., Mini, E., Messori, L., (2006) J. Med. Chem., 49, p. 5524
Cinellu, M.A., Maiore, L., Manassero, M., Casini, A., Arca, M., Fiebig, H.-H., Kelter, G., Messori, L., (2010) ACS Med. Chem. Lett., 1, p. 336
Messori, L., Scaletti, F., Massai, L., Cinellu, M.A., Gabbiani, C., Vergara, A., Merlino, A., (2013) Chem. Commun., 49, p. 10100
Mendes, F., Groessl, M., Nazarov, A.A., Tsybin, Y.O., Sava, G., Santos, I., Dyson, P.J., Casini, A., (2011) J. Med. Chem., 54, p. 2196
Kunitz, M., (1946) J. Biol. Chem., 164, p. 563
Merlino, A., Vitagliano, L., Ceruso, M.A., Di Nola, A., Mazzarella, L., (2002) Biopolymers, 65, p. 274
Sun, R. W. -Y., Lok, C. -N., Fong, T. T. -H., Li, C. K. -L., Yang, Z. F., Zou, T., Siu, A. F. -M., Che, C. -M., (2013) Chem. Sci., 4, p. 197
Zhang, J. -J., Sun, R. W. -Y., Che, C. -M., (2012) Chem. Commun., 48, p. 3388
Zhang, J. -J., Lu, W., Sun, R. W. -Y., Che, C. -M., (2012) Angew. Chem., Int. Ed., 51, p. 4882
Yan, J. J., Chow, A. L. -F., Leung, C. H., Sun, R. W. -Y., Ma, D. L., Che, C. -M., (2010) Chem. Commun., 46, p. 3893
Li, C. K. -L., Sun, R. W. -Y., Kui, S. C. -F., Zhu, N., Che, C. -M., (2006) Chem. -Eur. J., 12, p. 5253
Barnes, K. R., Lippard, S. J., (2004) Metal Ions Biol. Syst., Cisplatin and Related Anticancer Drugs: Recent Advances and Insights, 42, pp. 43-77. , ed. A. Sigel and H. Sigel, Marcel Dekker Inc., New York Basel Netherlands
Sun, R. W. -Y., Li, C. K. -L., Ma, D. -L., Yan, J. J., Lock, C. -N., Leung, C. -H., Zhu, N., Che, C. -M., (2010) Chem. -Eur. J., 16, p. 3097
Chow, K. H. -M., Sun, R. W. -Y., Lam, J. B. B., Li, C. K. -L., Xu, A., Ma, D. -L., Abagyan, R., Che, C. -M., (2010) Cancer Res., 70, p. 329
Lum, C. T., Yang, Z. F., Li, H. J., Sun, R. W. -Y., Fan, S. T., Poon, R. T., Lin, M. C. M., Kung, H. F., (2006) Int. J. Cancer, 118, p. 1527
Wang, Y., He, Q. Y., Sun, R. W. -Y., Che, C. -M., Chiu, J. F., (2005) Cancer Res., 65, p. 11553
Che, C. -M., Sun, R. W. -Y., Yu, W. -Y., Ko, C. -B., Zhu, N., Sun, H., (2003) Chem. Commun., p. 1718
De Vos, D., Ho, S. Y., Tiekink, E. R., (2004) Bioinorg. Chem. Appl., 2, p. 141
Zhang, C. X., Lippard, S. J., (2003) Curr. Opin. Chem. Biol., 7, p. 481
Bhabak, K. P., Bhuyan, B. J., Mugesh, G., (2011) Dalton Trans., 40, p. 2099
Richards, F. M., Wyckoff, H. W., (1971) The Enzymes, 4, pp. 647-806. , ed. D. Boyer, Academic Press, San Diego
Raines, R. T., (1998) Chem. Rev., 98, p. 1045
Marshal, G. R., Fengand, J. A., Kuster, D. J., (2008) Biopolymers, 90, p. 259
Isab, A. A., Sadler, P. J., (1977) Biochim. Biophys. Acta, 492, p. 322
Cinellu, M. A., Maiore, L., Manassero, M., Casini, A., Arca, M., Fiebig, H. -H., Kelter, G., Messori, L., (2010) ACS Med. Chem. Lett., 1, p. 336
Metallomics (ISSN: 1756-5901, 1756-591x), 2014; 6(2): 233-236.
Tipo di articolo: Journal Article,
Impact factor: 3.585, Impact factor a 5 anni: 3.98
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84893276097&partnerID=40&md5=6ba50ce6078b2777e720fe9dcdca3ca6
Parole chiave: Adduct Formation, Bovine Pancreatic Ribonuclease, Cytotoxic, Dinuclear, Esi Mass Spectrometry, Mode Of Action, Model Proteins, X Ray Diffraction, Gold, Auoxo6, Auranofin, Gold Complex, Histidine, Ligand, Metallodrug, Peroxiredoxin, Prodrug, Thioredoxin Reductase, Unclassified Drug, Antineoplastic Activity, Cattle, Chemical Structure, Complex Formation, Conference Paper, Crystal Structure, Electrospray Mass Spectrometry, Enzyme Activity, Nonhuman, Priority Journal, Animals, Cell Death, Crystallography, X-Ray, Hydrolysis, Molecular, Saccharomyces Cerevisiae, Electrospray Ionization,
Affiliazioni:
*** IBB - CNR ***
Department of Chemistry Ugo Schiff, Via della Lastruccia 3, 50019 Sesto Fiorentino (FI), Italy
Department of Chemical Sciences, University of Naples Federico II, Complesso Universitario di Monte sant'Angelo, Via Cintia I-80126, Napoli, Italy
CNR Institute of Biostructures and Bioimages, Napoli, Italy
Riferimenti:
Sun, R.W.-Y., Lok, C.-N., Fong, T.T.-H., Li, C.K.-L., Yang, Z.F., Zou, T., Siu, A.F.-M., Che, C.-M., (2013) Chem. Sci., 4, p. 197
Zhang, J.-J., Sun, R.W.-Y., Che, C.-M., (2012) Chem. Commun., 48, p. 3388
Zhang, J.-J., Lu, W., Sun, R.W.-Y., Che, C.-M., (2012) Angew. Chem., Int. Ed., 51, p. 4882
Yan, J.J., Chow, A.L.-F., Leung, C.H., Sun, R.W.-Y., Ma, D.L., Che, C.-M., (2010) Chem. Commun., 46, p. 3893
Li, C.K.-L., Sun, R.W.-Y., Kui, S.C.-F., Zhu, N., Che, C.-M., (2006) Chem.-Eur. J., 12, p. 5253
Nobili, S., Mini, E., Landini, I., Gabbiani, C., Casini, A., Messori, L., (2010) Med. Res. Rev., 30, p. 550
Barnes, K.R., Lippard, S.J., (2004) Metal Ions Biol. Syst., Cisplatin and Related Anticancer Drugs: Recent Advances and Insights, 42, pp. 43-77. , ed. A. Sigel and H. Sigel, Marcel Dekker Inc., New York Basel Netherlands
Sun, R.W.-Y., Li, C.K.-L., Ma, D.-L., Yan, J.J., Lock, C.-N., Leung, C.-H., Zhu, N., Che, C.-M., (2010) Chem.-Eur. J., 16, p. 3097
Chow, K.H.-M., Sun, R.W.-Y., Lam, J.B.B., Li, C.K.-L., Xu, A., Ma, D.-L., Abagyan, R., Che, C.-M., (2010) Cancer Res., 70, p. 329
Lum, C.T., Yang, Z.F., Li, H.J., Sun, R.W.-Y., Fan, S.T., Poon, R.T., Lin, M.C.M., Kung, H.F., (2006) Int. J. Cancer, 118, p. 1527
Wang, Y., He, Q.Y., Sun, R.W.-Y., Che, C.-M., Chiu, J.F., (2005) Cancer Res., 65, p. 11553
Che, C.-M., Sun, R.W.-Y., Yu, W.-Y., Ko, C.-B., Zhu, N., Sun, H., (2003) Chem. Commun., p. 1718
Cattaruzza, L., Fregona, D., Mongiat, M., Ronconi, L., Fassina, A., Colombatti, A., Aldinucci, D., (2011) Int. J. Cancer, 128, p. 206
Milacic, V., Chen, D., Ronconi, L., Landis-Piwowar, K.R., Fregona, D., Dou, Q.P., (2006) Cancer Res., 66, p. 10478
Ronconi, L., Giovagnini, L., Marzano, C., Bettio, F., Graziani, R., Pilloni, G., Fregona, D., (2005) Inorg. Chem., 44, p. 1867
Giovagnini, L., Ronconi, L., Aldinucci, D., Lorenzon, D., Sitran, S., Fregona, D., (2005) J. Med. Chem., 48, p. 1588
De Vos, D., Ho, S.Y., Tiekink, E.R., (2004) Bioinorg. Chem. Appl., 2, p. 141
Zhang, C.X., Lippard, S.J., (2003) Curr. Opin. Chem. Biol., 7, p. 481
Rosenberg, B., Van Camp, L., Trosko, J.E., Mansour, V.H., (1969) Nature, 222, p. 385
Zou, J., Taylor, P., Dornan, J., Robinson, S.P., Walkinshaw, M.D., Sadler, P.J., (2000) Angew. Chem., Int. Ed., 39, pp. 2931-2934
Urig, S., Fritz-Wolf, K., Réau, R., Herold-Mende, C., Tóth, K., Davioud-Charvet, E., Becker, K., (2006) Angew. Chem., Int. Ed., 45, p. 1881
Bhabak, K.P., Bhuyan, B.J., Mugesh, G., (2011) Dalton Trans., 40, p. 2099
Richards, F.M., Wyckoff, H.W., (1971) The Enzymes, 4, pp. 647-806. , ed. D. Boyer, Academic Press, San Diego
Raines, R.T., (1998) Chem. Rev., 98, p. 1045
Marshal, G.R., Fengand, J.A., Kuster, D.J., (2008) Biopolymers, 90, p. 259
D'Alessio, G., Riordan, J.F., (1997) Ribonucleases. Structures and Functions, , Academic Press, New York
Gutte, B., Merryfield, R.B., (1971) J. Biol. Chem., 246, p. 1922
Kartha, G., Bello, J., Harker, D., (1967) Nature, 213, p. 862
Merlino, A., Sica, F., Mazzarella, L., (2007) J. Phys. Chem., 111, p. 5483
Balakrishnan, R., Ramasubbu, N., Varughese, K.I., Parthasarathy, R., (1997) Proc. Natl. Acad. Sci. U. S. A., 94, p. 9620
Vergara, A., Montesarchio, D., Russo Krauss, I., Paduano, L., Merlino, A., (2013) Inorg. Chem., 52, p. 10714
Isab, A.A., Sadler, P.J., (1977) Biochim. Biophys. Acta, 492, p. 322
Maruyama, T., Sonokawa, S., Matsushita, H., Goto, M., (2007) J. Inorg. Biochem, 101, p. 180
Vitagliano, L., Merlino, A., Zagari, A., Mazzarella, L., (2000) Protein Sci., 9, p. 1217
Casini, A., Cinellu, M.A., Minghetti, G., Gabbiani, C., Coronnello, M., Mini, E., Messori, L., (2006) J. Med. Chem., 49, p. 5524
Cinellu, M.A., Maiore, L., Manassero, M., Casini, A., Arca, M., Fiebig, H.-H., Kelter, G., Messori, L., (2010) ACS Med. Chem. Lett., 1, p. 336
Messori, L., Scaletti, F., Massai, L., Cinellu, M.A., Gabbiani, C., Vergara, A., Merlino, A., (2013) Chem. Commun., 49, p. 10100
Mendes, F., Groessl, M., Nazarov, A.A., Tsybin, Y.O., Sava, G., Santos, I., Dyson, P.J., Casini, A., (2011) J. Med. Chem., 54, p. 2196
Kunitz, M., (1946) J. Biol. Chem., 164, p. 563
Merlino, A., Vitagliano, L., Ceruso, M.A., Di Nola, A., Mazzarella, L., (2002) Biopolymers, 65, p. 274
Sun, R. W. -Y., Lok, C. -N., Fong, T. T. -H., Li, C. K. -L., Yang, Z. F., Zou, T., Siu, A. F. -M., Che, C. -M., (2013) Chem. Sci., 4, p. 197
Zhang, J. -J., Sun, R. W. -Y., Che, C. -M., (2012) Chem. Commun., 48, p. 3388
Zhang, J. -J., Lu, W., Sun, R. W. -Y., Che, C. -M., (2012) Angew. Chem., Int. Ed., 51, p. 4882
Yan, J. J., Chow, A. L. -F., Leung, C. H., Sun, R. W. -Y., Ma, D. L., Che, C. -M., (2010) Chem. Commun., 46, p. 3893
Li, C. K. -L., Sun, R. W. -Y., Kui, S. C. -F., Zhu, N., Che, C. -M., (2006) Chem. -Eur. J., 12, p. 5253
Barnes, K. R., Lippard, S. J., (2004) Metal Ions Biol. Syst., Cisplatin and Related Anticancer Drugs: Recent Advances and Insights, 42, pp. 43-77. , ed. A. Sigel and H. Sigel, Marcel Dekker Inc., New York Basel Netherlands
Sun, R. W. -Y., Li, C. K. -L., Ma, D. -L., Yan, J. J., Lock, C. -N., Leung, C. -H., Zhu, N., Che, C. -M., (2010) Chem. -Eur. J., 16, p. 3097
Chow, K. H. -M., Sun, R. W. -Y., Lam, J. B. B., Li, C. K. -L., Xu, A., Ma, D. -L., Abagyan, R., Che, C. -M., (2010) Cancer Res., 70, p. 329
Lum, C. T., Yang, Z. F., Li, H. J., Sun, R. W. -Y., Fan, S. T., Poon, R. T., Lin, M. C. M., Kung, H. F., (2006) Int. J. Cancer, 118, p. 1527
Wang, Y., He, Q. Y., Sun, R. W. -Y., Che, C. -M., Chiu, J. F., (2005) Cancer Res., 65, p. 11553
Che, C. -M., Sun, R. W. -Y., Yu, W. -Y., Ko, C. -B., Zhu, N., Sun, H., (2003) Chem. Commun., p. 1718
De Vos, D., Ho, S. Y., Tiekink, E. R., (2004) Bioinorg. Chem. Appl., 2, p. 141
Zhang, C. X., Lippard, S. J., (2003) Curr. Opin. Chem. Biol., 7, p. 481
Bhabak, K. P., Bhuyan, B. J., Mugesh, G., (2011) Dalton Trans., 40, p. 2099
Richards, F. M., Wyckoff, H. W., (1971) The Enzymes, 4, pp. 647-806. , ed. D. Boyer, Academic Press, San Diego
Raines, R. T., (1998) Chem. Rev., 98, p. 1045
Marshal, G. R., Fengand, J. A., Kuster, D. J., (2008) Biopolymers, 90, p. 259
Isab, A. A., Sadler, P. J., (1977) Biochim. Biophys. Acta, 492, p. 322
Cinellu, M. A., Maiore, L., Manassero, M., Casini, A., Arca, M., Fiebig, H. -H., Kelter, G., Messori, L., (2010) ACS Med. Chem. Lett., 1, p. 336
The reaction of Auoxo6, a dinuclear gold(III) complex, with the model protein bovine pancreatic ribonuclease is explored here by X-ray diffraction and ESI mass spectrometry. Data provide clues on the processes of adduct formation and of enzyme inhibition and, inductively, on the likely mode of action of this metallodrug.
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Esposito R, Calvanese L, Cucciolito ME, D'Auria G, Falcigno L, Fiorini V, Pezzella P, Roviello G, Stagni S, Talarico G, Ruffo F
* Oxidative coupling of imino, amide platinum(II) complexes yields highly conjugated blue dimers (70 visite)
Organometallics (ISSN: 0276-7333), 2017; 36(2): 384-390.
Impact Factor: 4.051
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Cucciolito ME, Trinchillo M, Iannitti R, Palumbo R, Tesauro D, Tuzi A, Ruffo F, D'Amora A
* Sugar-Incorporated N-Heterocyclic-Carbene-Containing Gold(I) Complexes: Synthesis, Characterization, and Cytotoxic Evaluation (190 visite)
Eur J Inorg Chem (ISSN: 1434-1948, 1099-0682e), 2017; 2017(42): 4855-4961.
Impact Factor: 2.507
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Magri A, La Mendola D, Nicoletti VG, Pappalardo G, Rizzarelli E
* New Insight in Copper-Ion Binding to Human Islet Amyloid: The Contribution of Metal-Complex Speciation To Reveal the Polypeptide Toxicity (260 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2016 Sep 5; 22(37): 13287-13300.
Impact Factor: 5.317
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Sinopoli A, Giuffrida A, Tomasello MF, Giuffrida ML, Leone M, Attanasio F, Caraci F, De Bona P, Naletova I, Saviano M, Copani A, Pappalardo G, Rizzarelli E
* Ac-LPFFD-Th: A Trehalose-Conjugated Peptidomimetic as a Strong Suppressor of Amyloid-beta Oligomer Formation and Cytotoxicity (252 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-4227linking), 2016 Aug 17; 17(16): 1541-1549.
Impact Factor: 2.847
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Barresi V, Spampinato G, Musso N, Trovato Salinaro A, Rizzarelli E, Condorelli DF
* ATOX1 gene silencing increases susceptibility to anticancer therapy based on copper ionophores or chelating drugs (565 visite)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2016; 156: 145-152.
Impact Factor: 3.348
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Desplat V, Vincenzi M, Lucas R, Moreau S, Savrimoutou S, Pinaud N, Lesbordes J, Peyrilles E, Marchivie M, Routier S, Sonnet P, Rossi F, Ronga L, Guillon J
* Synthesis and evaluation of the cytotoxic activity of novel ethyl 4-[4-(4-substitutedpiperidin-1-yl)]benzyl-phenylpyrrolo[1, 2-a]quinoxaline-carboxylate derivatives in myeloid and lymphoid leukemia cell lines (225 visite)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 0223-5234linking), 2016; 113: 214-227.
Impact Factor: 4.519
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Tabbì G, Magrì A, Giuffrida A, Lanza V, Pappalardo G, Naletova I, Nicoletti VG, Attanasio F, Rizzarelli E
* Semax, an ACTH4-10 peptide analog with high affinity for copper(II) ion and protective ability against metal induced cell toxicity (287 visite)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2015 Jan; 142: 39-46.
Impact Factor: 3.205
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Nardon C, Boscutti G, Dalla Via L, Ringhieri P, Di Noto V, Morelli G, Accardo A, Fregona D
* CCK8 peptide-labeled Pluronic® F127 micelles as a targeted vehicle of gold-based anticancer chemotherapeutics (262 visite)
Medchemcomm (ISSN: 2040-2503), 2015; 6(1): 155-163.
Impact Factor: 2.319
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Avitabile C, Accardo A, Ringhieri P, Morelli G, Saviano M, Montagner G, Fabbri E, Gallerani E, Gambari R, Romanelli A
* Incorporation of Naked Peptide Nucleic Acids into Liposomes Leads to Fast and Efficient Delivery (277 visite)
Bioconjug Chem (ISSN: 1043-1802, 1520-4812), 2015; 26(8): 1533-1541.
Impact Factor: 4.5
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Tomasello MF, Sinopoli A, Pappalardo G
* On the Environmental Factors Affecting the Structural and Cytotoxic Properties of IAPP Peptides (292 visite)
J Diabetes Res (ISSN: 2314-6745), 2015; articleID918573: 918573-918573.
Impact Factor: 2.431
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Marasco D, Messori L, Marzo T, Merlino A
* Oxaliplatin vs. cisplatin: Competition experiments on their binding to lysozyme (591 visite)
Dalton T (ISSN: 1477-9226, 1477-9234, 1477-9226linking), 2015; 44(22): 10392-10398.
Impact Factor: 4.177
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Napolitano M, D'Alterio C, Cardone E, Trotta AM, Pecori B, Rega D, Pace U, Scala D, Scognamiglio G, Tatangelo F, Cacciapuoti C, Pacelli R, Delrio P, Scala S
* Peripheral myeloid-derived suppressor and T regulatory PD-1 positive cells predict response to neoadjuvant short-course radiotherapy in rectal cancer patients (212 visite)
Oncotarget (ISSN: 1949-2553, 1949-2553electronic), 2015; 6(10): 8261-8270.
Impact Factor: 5.008
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Picone D, Donnarumma F, Ferraro G, Russo Krauss I, Fagagnini A, Gotte G, Merlino A
* Platinated oligomers of bovine pancreatic ribonuclease: Structure and stability (269 visite)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2015; 146: 37-43.
Impact Factor: 3.205
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Petruk AA, Vergara A, Marasco D, Bikiel D, Doctorovich F, Estrin DA, Merlino A
* Interaction between Proteins and Ir Based CO Releasing Molecules: Mechanism of Adduct Formation and CO Release (262 visite)
Inorg Chem (ISSN: 0020-1669, 1520-510x, 0020-1669linking), 2014 Oct 6; 53(19): 10456-10462.
Impact Factor: 4.762
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Ringhieri P, Iannitti R, Nardon C, Palumbo R, Fregona D, Morelli G, Accardo A
* Target selective micelles for bombesin receptors incorporating Au(III)-dithiocarbamato complexes (262 visite)
Int J Pharm (ISSN: 0378-5173, 1873-3476), 2014 Oct 1; 473(1-2): 194-202.
Impact Factor: 3.65
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Capasso D, De Paola I, Liguoro A, Del Gatto A, Di Gaetano S, Guarnieri D, Saviano M, Zaccaro L
* Rgdechi-Hcit: Alpha V Beta 3 Selective Pro-Apoptotic Peptide As Potential Carrier For Drug Delivery Into Melanoma Metastatic Cells (264 visite)
Plosone (ISSN: 1932-6203, 1932-6203electronic), 2014 Sep 23; 9(9): e106441-e106441.
Impact Factor: 3.234
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Oppermann S, Schrader FC, Elsasser K, Dolga AM, Kraus AL, Doti N, Wegscheid-Gerlach C, Schlitzer M, Culmsee C
* Novel N-Phenyl-Substituted Thiazolidinediones Protect Neural Cells against Glutamate- and tBid-Induced Toxicity (336 visite)
J Pharmacol Exp Ther (ISSN: 0022-3565, 1521-0103), 2014 Sep; 350(2): 273-289.
Impact Factor: 3.972
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Tomasello MF, Sinopoli A, Attanasio F, Giuffrida ML, Campagna T, Milardi D, Pappalardo G
* Molecular and cytotoxic properties of hIAPP17-29 and rIAPP17-29 fragments: A comparative study with the respective full-length parent polypeptides (484 visite)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 0223-5234linking), 2014 Jun 23; 81: 442-455.
Impact Factor: 3.447
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Rai M, Kon K, Ingle A, Duran N, Galdiero S, Galdiero M
* Broad-spectrum bioactivities of silver nanoparticles: the emerging trends and future prospects (528 visite)
Appl Microbiol Biot (ISSN: 0175-7598), 2014 Mar; 98(5): 1951-1961.
Impact Factor: 3.337
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Russo Krauss I, Messori L, Cinellu MA, Marasco D, Sirignano R, Merlino A
* Interactions of gold-based drugs with proteins: the structure and stability of the adduct formed in the reaction between lysozyme and the cytotoxic gold(III) compound Auoxo3 (241 visite)
Dalton T (ISSN: 1477-9226, 1477-9234, 1477-9226linking), 2014; 43(46): 17483-17488.
Impact Factor: 4.197
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Milardi D, Sciacca MF, Randazzo L, Raudino A, La Rosa C
* The role of calcium, lipid membranes and islet amyloid polypeptide in the onset of type 2 diabetes: Innocent bystanders or partners in a crime? (290 visite)
Front Endocrinol (ISSN: 1664-2392, 1664-2392linking, 1664-2392print), 2014; 5(DEC): 216-216.
Impact Factor: 3.675
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Sica F, Pica A, Merlino A, Russo Krauss I, Ercole C, Picone D
* The multiple forms of bovine seminal ribonuclease: Structure and stability of a C-terminal swapped dimer (193 visite)
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 2013 Nov 29; 587(23): 3755-3762.
Impact Factor: 3.341
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Passaro C, Abagnale A, Libertini S, Volpe M, Botta G, Cella L, Pacelli R, Halldèn G, Gillespie D, Portella G
* Ionizing radiation enhances dl922-947-mediated cell death of anaplastic thyroid carcinoma cells (275 visite)
Endocr Relat Cancerendocrine Related Cancer (ISSN: 1351-0088), 2013 Sep 19; 20(5): 633-647.
Impact Factor: 4.907
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Pellerito O, Prinzivalli C, Foresti E, Sabatino P, Abbate M, Casella G, Fiore T, Scopelliti M, Pellerito C, Giuliano M, Grasso G, Pellerito L
* Synthesis, chemical characterization and biological activity of new histone acetylation/deacetylation specific inhibitors: A novel and potential approach to cancer therapy (268 visite)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 2013 Sep; 125: 16-25.
Impact Factor: 3.274
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De Simonea A, Stanzione F, Marasco D, Vitagliano L, Esposito L
* The Intrinsic Stability Of The Human Prion Beta-Sheet Region Investigated By Molecular Dynamics (365 visite)
Journal Of Biomolecular Structure & Dynamics, 2013 May 1; 31(5): 441-452.
Impact Factor: 2.983
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Falciani C, Brunetti J, Lelli B, Accardo A, Tesauro D, Morelli G, Bracci L
* Nanoparticles exposing neurotensin tumor-specific drivers (292 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2013 Apr; 19(4): 198-204.
Impact Factor: 1.862
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D'Angelo D, Borbone E, Palmieri D, Uboldi S, Esposito F, Frapolli R, Pacelli R, D'Incalci M, Fusco A
* The impairment of the High Mobility Group A (HMGA) protein function contributes to the anticancer activity of trabectedin (260 visite)
European Journal Of Cancer (ISSN: 0959-8049), 2013 Mar; 49(5): 1142-1151.
Impact Factor: 4.819
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Tedesco I, Russo M, Bilotto S, Spagnuolo C, Scognamiglio A, Palumbo R, Nappo A, Iacomino G, Moio L, Russo GL
* Dealcoholated red wine induces autophagic and apoptotic cell death in an osteosarcoma cell line (261 visite)
Food Chem Toxicol (ISSN: 0278-6915), 2013; 60: 377-384.
Impact Factor: 2.61
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Messori L, Scaletti F, Massai L, Cinellu MA, Gabbiani C, Vergara A, Merlino A
* The mode of action of anticancer gold-based drugs: a structural perspective (227 visite)
Chem Commun (ISSN: 1359-7345, 1364-548x, 1364-548xelectronic), 2013; 49(86): 10100-10102.
Impact Factor: 6.718
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Accardo A, Mansi R, Salzano G, Morisco A, Aurilio M, Parisi A, Maione F, Cicala C, Ziaco B, Tesauro D, Aloj L, De Rosa G, Morelli G
* Bombesin peptide antagonist for target-selective delivery of liposomal doxorubicin on cancer cells (264 visite)
Journal Of Drug Targeting (ISSN: 1061-186x), 2012 Nov 21; 21(3): 240-249.
Impact Factor: 2.768
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Merlino A, Picone D, Ercole C, Balsamo A, Sica F
* Chain termini cross-talk in the swapping process of bovine pancreatic ribonuclease (162 visite)
Biochimie (ISSN: 0300-9084, 1638-6183, 1638-6183electronic), 2012 May; 94(5): 1108-1118.
Impact Factor: 3.142
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De Rosa V, Erkekoǧlu P, Forestier A, Favier A, Hincal F, Diamond AM, Douki T, Rachidi W
* Low doses of selenium specifically stimulate the repair of oxidative DNA damage in LNCaP prostate cancer cells (255 visite)
Free Radic Res Free Radical Research (ISSN: 1071-5762), 2012; 46(2): 105-115.
Impact Factor: 3.279
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Accardo A, Salsano G, Morisco A, Aurilio M, Parisi A, Maione F, Cicala C, Tesauro D, Aloj L, De Rosa G, Morelli G
* Peptide-modified liposomes for selective targeting of bombesin receptors overexpressed by cancer cells: A potential theranostic agent (261 visite)
Int J Nanomed (ISSN: 1176-9114, 1178-2013, 1178-2013electronic), 2012; 7: 2007-2017.
Impact Factor: 3.463
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D'Errico G, Ercole C, Lista M, Pizzo E, Falanga A, Galdiero S, Spadaccini R, Picone D
* Enforcing the positive charge of N-termini enhances membrane interaction and antitumor activity of bovine seminal ribonuclease (288 visite)
Bba-Gen Subjects (ISSN: 0005-2736, 0006-3002, 0925-4439), 2011 Dec; 1808(12): 3007-3015.
Impact Factor: 3.99
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Tarallo R, Accardo A, Falanga A, Guarnieri D, Vitiello G, Netti P, D'Errico G, Morelli G, Galdiero S
* Clickable functionalization of liposomes with the gH625 peptide from herpes simplex virus type i for intracellular drug delivery (289 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2011 Nov 4; 17(45): 12659-12668.
Impact Factor: 5.925
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Adinolfi M, Capasso D, Di Gaetano S, Iadonisi A, Leone L, Pastore A
* A straightforward synthetic access to symmetrical glycosyl disulfides and biological evaluation thereof (233 visite)
Org Biomol Chem (ISSN: 1477-0520, 1477-0539, 1477-0539electronic), 2011 Sep 21; 9(18): 6278-6283.
Impact Factor: 3.696
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Falciani C, Accardo A, Brunetti J, Tesauro D, Lelli B, Pini A, Bracci L, Morelli G
* Target-Selective Drug Delivery through Liposomes Labeled with Oligobranched Neurotensin Peptides (300 visite)
Chemmedchem (ISSN: 1860-7179, 1860-7187, 1860-7187electronic), 2011 Apr 4; 6(4): 678-685.
Impact Factor: 3.151
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Rachidi W, De Rosa V
Selenium protects against the cytotoxic and genotoxic effects of oxidative stress both as an anti-oxidant and by stimulating DNA damage repair (145 visite)
Bulletin Du Cancer (ISSN: 0007-4551), 2011 Mar; 98: N/D-N/D.
Impact Factor: 0.672
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Józsa E, Osz K, Kállay C, de Bona P, Damante CA, Pappalardo G, Rizzarelli E, Sóvágó I
* Nickel(ii) and mixed metal complexes of amyloid-β N-terminus (305 visite)
Dalton T (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2010 Sep 14; 39(30): 7046-7053.
Impact Factor: 3.647
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Erkekoǧlu P, Rachidi W, De Rosa V, Giray B, Favier A, Hincal F
* Protective effect of selenium supplementation on the genotoxicity of di(2-ethylhexyl)phthalate and mono(2-ethylhexyl)phthalate treatment in LNCaP cells (228 visite)
Free Radic Biol Med (ISSN: 0891-5849, 0891-5849linking, 1873-4596electronic), 2010 Aug 15; 49(4): 559-566.
Impact Factor: 5.707
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Jozsa E, Hosz K, Kallay C, De Bona P, Damante CA, Pappalardo G, Rizzarelli E, Sovago I
* Nickel (ii) And Mixed Metal Complexes Of Amyloid-B N-Terminus. Results Of Potentiometric And Spectroscopic Studies On The Binary Nickel (ii) And Mixed Metal Nickel (ii)-Copper (ii) And Nickel (ii)-Copper (ii)-Zinc (ii) Complexes Of Peptide Fragments (257 visite)
Dalton T (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2010; 39(30): 7046-7053.
Impact Factor: 3.647
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Merlino A, Russo Krauss I, Perillo M, Mattia CA, Ercole C, Picone D, Vergara A, Sica F
* Toward an Antitumor Form of Bovine Pancreatic Ribonuclease: The Crystal Structure of Three Noncovalent Dimeric Mutants (245 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2009 Dec; 91(12): 1029-1037.
Impact Factor: 2.605
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Calabrese V, Cornelius C, Rizzarelli E, Owen JB, Dinkova-Kostova AT, Butterfield DA
* Nitric oxide in cell survival: a janus molecule (222 visite)
Antioxid Redox Signal (ISSN: 1557-7716, 1523-0864, 1523-0864linking), 2009 Nov; 11(11): 2717-2739.
Impact Factor: 7.581
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Merlino A, Avella G, Di Gaetano S, Arciello A, Piccoli R, Mazzarella L, Sica F
* Structural features for the mechanism of antitumor action of a dimeric human pancreatic ribonuclease variant (225 visite)
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic, 0961-8368linking), 2009 Jan; 18(1): 50-57.
Impact Factor: 2.937
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Bonomo RP, Pappalardo G, Rizzarelli E, Tabbì G, Vagliasindi LI
* Studies of nitric oxide interaction with mono- and dinuclear copper(II) complexes of prion protein bis-octarepeat fragments (215 visite)
Dalton T (ISSN: 1477-9226, 1477-9234, 1477-9234electronic), 2008 Sep 7; (29): 3805-3816.
Impact Factor: 3.58
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Merlino A, Ercole C, Picone D, Pizzo E, Mazzarella L, Sica F
* The buried diversity of bovine seminal ribonuclease: Shape and cytotoxicity of the swapped non-covalent form of the enzyme (239 visite)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2008 Feb 15; 376(2): 427-437.
Impact Factor: 4.146
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Zeni O, Palumbo R, Bernini R, Zeni L, Sarti M, Scarfi MR
* Cytotoxicity investigation on cultured human blood cells treated with single-wall carbon nanotubes (201 visite)
Sensors (ISSN: 1424-3210, 1424-8220, 1424-8220electronic), 2008 Jan; 8(1): 488-499.
Impact Factor: 1.87
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Zeni O, Palumbo R, Bernini R, Zeni L, Sarti M, Scarf MR
* Cytotoxicity Investigation On Cultured Human Blood Cells Treated With Single-Wall Carbon Nanoyubes (143 visite)
Sensors, 2008; 8: 488-499.
Impact Factor: 2.245
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Dalla Bona A, Formaggio F, Peggion C, Kaptein B, Broxterman Quirinus B, Galdiero S, Galdiero M, Vitiello M, Benedetti E, Toniolo C
* Synthesis, conformation, and bioactivity of novel analogues of the antiviral lipopeptide halovir (288 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2006 Dec; 12(12): 748-757.
Impact Factor: 1.801
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Marrazzo A, Caraci F, Salinaro ET, Su TP, Copani A, Ronsisvalle G
* Neuroprotective effects of sigma-1 receptor agonists against beta-amyloid-induced toxicity (358 visite)
Neuroreport (ISSN: 0959-4965), 2005 Sep 1; 16(11): 1223-1226.
Impact Factor: 1.995
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Naddeo M, Vitagliano L, Russo A, Gotte G, D'Alessio G, Sorrentino S
* Interactions of the cytotoxic RNase A dimers with the cytosolic ribonuclease inhibitor (202 visite)
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 2005 May 9; 579(12): 2663-2668.
Impact Factor: 3.415
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Cozzolino R, Palladino P, Rossi F, Cali G, Benedetti E, Laccetti P
* Antineoplastic cyclic astin analogues kill tumour cells via caspase-mediated induction of apoptosis (287 visite)
Carcinogenesis (ISSN: 0143-3334), 2005 Apr; 26(4): 733-739.
Impact Factor: 5.108
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Esposito L, Daggett V
* Insight into ribonuclease A domain swapping by molecular dynamics unfolding simulations (278 visite)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2005 Mar 8; 44(9): 3358-3368.
Impact Factor: 3.848
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Tedesco I, Nappo A, Petitto F, Iacomino G, Nazzaro F, Palumbo R, Russo Gian L
* Antioxidant and cytotoxic properties of lyophilized beer extracts on HL-60 cell line (243 visite)
Nutr Cancer (ISSN: 0163-5581), 2005; 52(1): 74-83.
Impact Factor: 2.426
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Sica F, Di Fiore A, Merlino A, Mazzarella L
* Structure and stability of the non-covalent swapped dimer of bovine seminal ribonuclease - An enzyme tailored to evade ribonuclease protein inhibitor (196 visite)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2004 Sep 27; 279(35): 36753-36760.
Impact Factor: 6.355
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Cortesi R, Mischiati C, Borgatti M, Breda L, Romanelli A, Saviano M, Pedone C, Gambari R, Nastruzzi C
* Formulations for natural and peptide nucleic acids based on cationic polymeric submicron particles (261 visite)
The Aaps Journal (ISSN: 1522-1059, 1550-7416), 2004 Jan 20; 6(1): N/D-N/D.
Impact Factor: 1.938
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Portella G, Pacelli R, Libertini S, Cella L, Vecchio G, Salvatore M, Fusco A
* ONYX-015 Enhances Radiation-Induced Death of Human Anaplastic Thyroid Carcinoma Cells (270 visite)
J Clin Endocrinol Metab Journal Of Clinical Endocrinology And Metabolism (ISSN: 0021-972x), 2003 Oct 1; 88(10): 5027-5032.
Impact Factor: 5.873
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Russo M, Palumbo R, Mupo A, Tosto M, Iacomino G, Scognamiglio A, Tedesco I, Galano G, Russo GL
* Flavonoid quercetin sensitizes a CD95-resistant cell line to apoptosis by activating protein kinase Cα (235 visite)
Oncogene (ISSN: 0950-9232, 1476-5594), 2003; 22(21): 3330-3342.
Impact Factor: 6.495
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Esposito G, Ligresti A, Izzo AA, Bisogno T, Ruvo M, Di Rosa M, Di Marzo V, Iuvone T
* The endocannabinoid system protects rat glioma cells against HIV-1 Tat protein-induced cytotoxicity: Mechanism and regulation (302 visite)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2002 Dec 27; 277(52): 50348-50354.
Impact Factor: 6.696
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Tabbì G, Cassino C, Cavigiolio G, Colangelo D, Ghiglia A, Viano I, Osella D
* Water stability and cytotoxic activity relationship of a series of ferrocenium derivatives. ESR insights on the radical production during the degradation process (329 visite)
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2002 Dec 19; 45(26): 5786-5796.
Impact Factor: 4.566
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Casella L, Monzani E, Gullotti M, Zoppellaro G, Pagliarin R, Bonomo RP, Tabbì G, Nardin G, Randaccio L
Synthetic Models For Biological Trinuclear Copper Clusters. Trinuclear And Dinuclear Complexes Derived From An Octadentate Tetraamin-Tetrabenzimidazole Ligand (197 visite)
Inorg Chim Acta, 1998; 282: 180-192.
Impact Factor: 0
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Monzani E, Quinti L, Perrotti A, Casella L, Gullotti M, Randaccio L, Geremia S, Nardin G, Faleschini P, Tabbì G
Tyrosinase Models. Synthesis, Structure, Catechol Oxidase Activity, And Phenol Monoxygenase Activity Of A Dinuclear Copper Complex Derived From A Triamino Pentabenzimidazole Ligand (181 visite)
Inorg Chem, 1998; 37: 553-562.
Impact Factor: 0
Dettagli Esporta in BibTeX Esporta in EndNote
Cook JA, Krishna MC, Pacelli R, DeGraff W, Liebmann J, Mitchell JB, Russo A, Wink DA
Nitric oxide enhancement of melphalan-induced cytotoxicity (302 visite)
Br J Cancer (ISSN: 0007-0920, 0007-0920print, 0007-0920linking), 1997 Sep; 76(3): 325-334.
Impact Factor: 2.938
Dettagli Esporta in BibTeX Esporta in EndNote
Wink DA, Cook JA, Christodoulou D, Krishna MC, Pacelli R, Kim S, DeGraff W, Gamson J, Vodovotz Y, Russo A, Mitchell JB
Nitric oxide and some nitric oxide donor compounds enhance the cytotoxicity of cisplatin (301 visite)
Nitric Oxide Biology And Chemistry (ISSN: 1089-8603), 1997 Feb; 1(1): 88-94.
Impact Factor: 2.151
Dettagli Esporta in BibTeX Esporta in EndNote
Wink DA, Cook JA, Pacelli R, DeGraff W, Gamson J, Liebmann J, Krishna MC, Mitchell JB
The effect of various nitric oxide-donor agents on hydrogen peroxide-mediated toxicity: A direct correlation between nitric oxide formation and protection (312 visite)
Arch Biochem Biophys (ISSN: 0003-9861), 1996 Jul 15; 331(2): 241-248.
Impact Factor: 2.649
Dettagli Esporta in BibTeX Esporta in EndNote
Veldman N, Spek AL, Tabbì G, Driessen WL, Reedijk J
A dinuclear nickel(II) compound: μ-{N, N, N′, N′-tetrakis[2-(3, 5-dimethyl-1-pyrazolyl)ethyl]-1, 2- ethylenediamine}-bis[aqua(nitrato-Ο, Ο + ′)nickel(II)] dinitrate dimethanol solvate (170 visite)
Acta Crystallogr Sect C Cryst Struct Commun (ISSN: 0108-2701), 1996; 52(11): 2698-2701.
Impact Factor: 0.459
Dettagli Esporta in BibTeX Esporta in EndNote
Wink DA, Hanbauer I, Grisham MB, Laval F, Nims RW, Laval J, Cook J, Pacelli R, Liebmann J, Krishna M, Ford PC, Mitchell JB
Chemical biology of nitric oxide: Regulation and protective and toxic mechanisms (257 visite)
Current Topics In Cellular Regulation (ISSN: 0070-2137), 1996; 34: 159-187.
Impact Factor: 4.375
Dettagli Esporta in BibTeX Esporta in EndNote
Capasso S, Di Donato A, Esposito L, Sica F, Sorrentino G, Vitagliano L, Zagari A, Mazzarella L
Deamidation in proteins: The crystal structure of bovine pancreatic ribonuclease with an isoaspartyl residue at position 67 (258 visite)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 1996; 257(3): 492-496.
Impact Factor: 5.673
Dettagli Esporta in BibTeX Esporta in EndNote
Wink DA, Cook JA, Pacelli R, Liebmann J, Krishna MC, Mitchell JB
Nitric oxide (NO) protects against cellular damage by reactive oxygen species (273 visite)
Toxicology Letters (ISSN: 0378-4274), 1995 Dec; 82-3: 221-226.
Impact Factor: 1.128
Dettagli Esporta in BibTeX Esporta in EndNote
Pacelli R, Wink DA, Cook JA, Krishna MC, DeGraff W, Friedman N, Tsokos M, Samuni A, Mitchell JB
NITRIC-OXIDE POTENTIATES HYDROGEN PEROXIDE-INDUCED KILLING OF ESCHERICHIA-COLI (317 visite)
Journal Of Experimental Medicine (ISSN: 0022-1007), 1995 Nov 1; 182(5): 1469-1479.
Impact Factor: 14.384
Dettagli Esporta in BibTeX Esporta in EndNote
Arena G, Bindoni M, Cardile V, Maccarrone G, Riello MC, Rizzarelli E, Sciuto S
Cytotoxic and cytostatic activity of copper(II) complexes. Importance of the speciation for the correct interpretation of the in vitro biological results (347 visite)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 1993 Apr 1; 50(1): 31-45.
Impact Factor: 1.342
Dettagli Esporta in BibTeX Esporta in EndNote
80 Records (77 escludendo Abstract e Conferenze).
Impact factor totale: 288.144 (279.297 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 283.633 (274.961 escludendo Abstract e Conferenze).
Impact factor totale: 288.144 (279.297 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 283.633 (274.961 escludendo Abstract e Conferenze).
Esporta in BibTeX Esporta in EndNote
Ultima modifica di Marco Comerci in data Thursday 19 March 2015, 16:43:13
172 visite. Ultima visita in data Tuesday 07 July 2020, 18:09:55
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