Expression and purification of the D4 region of PLD1 and characterization of its interaction with PED-PEA15 (185 visite)
Protein Expr Purif (ISSN: 1046-5928), 2008 Jun; 59(2): 302-308.
Tipo di articolo: Journal Article,
Impact factor: 1.621, Impact factor a 5 anni: 1.761
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-42749089546&partnerID=40&md5=17dd299046dc8eb5c67b73e880bcba43
Parole chiave: Phospholipase, Phosphoprotein Enriched In Diabetes (ped), Protein-Protein Interaction, Pea15 Protein, Human, Phospholipase D1, Signal Peptide, Article, Biosynthesis, Chemistry, Enzyme Linked Immunosorbent Assay, Genetics, Isolation And Purification, Molecular Cloning, Protein Tertiary Structure, Surface Plasmon Resonance, Enzyme-Linked Immunosorbent Assay, Intracellular Signaling Peptides And Proteins, Protein Structure,
Affiliazioni:
*** IBB - CNR ***
Istituto di Biostrutture e Bioimmagini (IBB), CNR, via Mezzocannone, 16, 80134 Napoli, Italy
Dipartimento di Scienze Biologiche, Università di Napoli Federico II, via Mezzocannone, 16, 80134 Napoli, Italy
Dipartimento di Biochimica e Biofisica, Seconda Università di Napoli, Via S.M. di Costantinopoli 16, 80138 Napoli, Italy
Istituto di Endocrinologia ed Oncologia Sperimentale (IEOS), CNR, Via Pansini, 5, 80131 Napoli, Italy
Riferimenti:
McDermott, M., Wakelam, M.J.O., Morris, A.J., Phospholipase D 1,2, Biochem (2004) Cell Biol., 82, pp. 225-25
Besterman, J.M., Duronio, V., Cuatrecasa, P., Rapid formation of diacylglycerol from phosphatidylcholine: a pathway for generation of a second messenger (1986) Proc. Natl. Acad. Sci. USA, 83, pp. 6785-6789
Sung, T.C., Zhang, Y., Morris, A.J., Frohman, M.A., Structural analysis of human phospholipase D1 (1999) J. Biol. Chem., 274, pp. 3659-3666
Sung, T.C., Altshuller, Y.M., Morris, A.J., Frohman, M.A., Molecular analysis of mammalian phospholipase D2 (1999) J. Biol. Chem., 274, pp. 494-502
Sung, T.C., Roper, R., Zhang, Y., Rudge, S.A., Temel, R., Hammond, S.M., Morris, A.J., Frohman, M.A., Mutagenesis of Phospholipase D defines a superfamily including a trans-golgi viral protein required for poxvirus pathogenicity (1997) EMBO J., 16, pp. 4519-4539
Stuckey, J.A., Dixon, J.E., Crystal structure of a phospholipase D member (1999) Nat. Struct. Biol., 6, pp. 278-284
Davies, D.R., Interthal, H., Champoux, J.J., Hol, W.G., The crystal structure of human tyrosyl-DNA phosphodiesterase, Tdp1 (2002) Structure, 10, pp. 237-248
Leiros, I., Secundo, F., Zambonelli, C., Servi, S., Hough, E., The first crystal structure of a phospholipase D (2000) Structure, 8, pp. 655-667
Ponting, C.P., Kerr, I.D., A novel family of phospholipase D homologues that includes phospholipid synthases and putative endonucleases: identification of duplicated repeats and potential active site residues (1996) Protein Sci., 5, pp. 914-922
Xie, Z., Ho, W.T., Exton, J., Association of the N- and C-terminal domains of Phospholipase D (2000) J. Biol. Chem., 275, pp. 24962-24969
Kam, Y., Exton, J.H., Dimerization of phospholipase D isozymes (2002) Biochem. Biophys. Res. Commun., 290, pp. 375-380
Exton, J.H., Phospholipase D-structure, regulation and function (2002) Rev. Physiol. Biochem. Pharmacol., 144, pp. 1-94
Zhang, Y., Redina, O., Altshuller, Y.M., Yamazaki, M., Ramos, J., Chneiweiss, H., Kanaho, Y., Frohman, M.A., Regulation of expression of Phospholipase D1 and D2 by PEA-15, a novel protein that interacts with them (2000) J. Biol. Chem., 275, pp. 35224-35232
Vigliotta, G., Miele, C., Santopietro, S., Portella, G., Perfetti, A., Maitan, M.A., Cassese, A., Beguinot, F., Overexpression of the PED/PEA15 gene causes diabetes by impairing glucose-stimulated insulin secretion in addition to insulin action (2004) Mol. Cell. Biol., 24, pp. 5005-5015
Condorelli, G., Vigliotta, G., Iavarone, C., Caruso, M., Tocchetti, C.G., Andreozzi, F., Cafieri, A., Beguinot, F., PED/PEA-15 gene controls glucose transport and is overexpressed in type 2 diabetes mellitus (1998) EMBO J., 17, pp. 3858-3866
Xiao, C., Yang, B.F., Asadi, N., Beguinot, F., Hao, C., Tumor necrosis factor-related apoptosis-inducing signaling complex and its modulation by c-Flip and PED/PEA-15 in glioma cells (2002) J. Biol. Chem., 277 (28), pp. 25020-25025
Condorelli, G., Trencia, A., Vigliotta, G., Perfetti, A., Goglia, U., Cassese, A., Musti, A.M., Beguinot, F., Multiple members of the mitogen-activated protein kinase family are necessary for PED/PEA15 anti-apoptotic function (2002) J. Biol. Chem., 277, pp. 11013-11018
Johnsson, B., Lofas, S., Lindquist, G., Immobilization of proteins to a carboxylmethyl dextran modified gold surface for biospecific interaction analysis in SPR sensors (1991) Anal. Biochem., 198, pp. 268-277
Hill, J.M., Vaidyanathan, H., Ramos, J.W., Ginsberg, M.H., Werner, M.H., Recognition of ERK MAP kinase by PEA-15 reveals a common docking site within the death domain and death effector domain (2002) EMBO J., 21, pp. 6494-6504
Protein Expr Purif (ISSN: 1046-5928), 2008 Jun; 59(2): 302-308.
Tipo di articolo: Journal Article,
Impact factor: 1.621, Impact factor a 5 anni: 1.761
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-42749089546&partnerID=40&md5=17dd299046dc8eb5c67b73e880bcba43
Parole chiave: Phospholipase, Phosphoprotein Enriched In Diabetes (ped), Protein-Protein Interaction, Pea15 Protein, Human, Phospholipase D1, Signal Peptide, Article, Biosynthesis, Chemistry, Enzyme Linked Immunosorbent Assay, Genetics, Isolation And Purification, Molecular Cloning, Protein Tertiary Structure, Surface Plasmon Resonance, Enzyme-Linked Immunosorbent Assay, Intracellular Signaling Peptides And Proteins, Protein Structure,
Affiliazioni:
*** IBB - CNR ***
Istituto di Biostrutture e Bioimmagini (IBB), CNR, via Mezzocannone, 16, 80134 Napoli, Italy
Dipartimento di Scienze Biologiche, Università di Napoli Federico II, via Mezzocannone, 16, 80134 Napoli, Italy
Dipartimento di Biochimica e Biofisica, Seconda Università di Napoli, Via S.M. di Costantinopoli 16, 80138 Napoli, Italy
Istituto di Endocrinologia ed Oncologia Sperimentale (IEOS), CNR, Via Pansini, 5, 80131 Napoli, Italy
Riferimenti:
McDermott, M., Wakelam, M.J.O., Morris, A.J., Phospholipase D 1,2, Biochem (2004) Cell Biol., 82, pp. 225-25
Besterman, J.M., Duronio, V., Cuatrecasa, P., Rapid formation of diacylglycerol from phosphatidylcholine: a pathway for generation of a second messenger (1986) Proc. Natl. Acad. Sci. USA, 83, pp. 6785-6789
Sung, T.C., Zhang, Y., Morris, A.J., Frohman, M.A., Structural analysis of human phospholipase D1 (1999) J. Biol. Chem., 274, pp. 3659-3666
Sung, T.C., Altshuller, Y.M., Morris, A.J., Frohman, M.A., Molecular analysis of mammalian phospholipase D2 (1999) J. Biol. Chem., 274, pp. 494-502
Sung, T.C., Roper, R., Zhang, Y., Rudge, S.A., Temel, R., Hammond, S.M., Morris, A.J., Frohman, M.A., Mutagenesis of Phospholipase D defines a superfamily including a trans-golgi viral protein required for poxvirus pathogenicity (1997) EMBO J., 16, pp. 4519-4539
Stuckey, J.A., Dixon, J.E., Crystal structure of a phospholipase D member (1999) Nat. Struct. Biol., 6, pp. 278-284
Davies, D.R., Interthal, H., Champoux, J.J., Hol, W.G., The crystal structure of human tyrosyl-DNA phosphodiesterase, Tdp1 (2002) Structure, 10, pp. 237-248
Leiros, I., Secundo, F., Zambonelli, C., Servi, S., Hough, E., The first crystal structure of a phospholipase D (2000) Structure, 8, pp. 655-667
Ponting, C.P., Kerr, I.D., A novel family of phospholipase D homologues that includes phospholipid synthases and putative endonucleases: identification of duplicated repeats and potential active site residues (1996) Protein Sci., 5, pp. 914-922
Xie, Z., Ho, W.T., Exton, J., Association of the N- and C-terminal domains of Phospholipase D (2000) J. Biol. Chem., 275, pp. 24962-24969
Kam, Y., Exton, J.H., Dimerization of phospholipase D isozymes (2002) Biochem. Biophys. Res. Commun., 290, pp. 375-380
Exton, J.H., Phospholipase D-structure, regulation and function (2002) Rev. Physiol. Biochem. Pharmacol., 144, pp. 1-94
Zhang, Y., Redina, O., Altshuller, Y.M., Yamazaki, M., Ramos, J., Chneiweiss, H., Kanaho, Y., Frohman, M.A., Regulation of expression of Phospholipase D1 and D2 by PEA-15, a novel protein that interacts with them (2000) J. Biol. Chem., 275, pp. 35224-35232
Vigliotta, G., Miele, C., Santopietro, S., Portella, G., Perfetti, A., Maitan, M.A., Cassese, A., Beguinot, F., Overexpression of the PED/PEA15 gene causes diabetes by impairing glucose-stimulated insulin secretion in addition to insulin action (2004) Mol. Cell. Biol., 24, pp. 5005-5015
Condorelli, G., Vigliotta, G., Iavarone, C., Caruso, M., Tocchetti, C.G., Andreozzi, F., Cafieri, A., Beguinot, F., PED/PEA-15 gene controls glucose transport and is overexpressed in type 2 diabetes mellitus (1998) EMBO J., 17, pp. 3858-3866
Xiao, C., Yang, B.F., Asadi, N., Beguinot, F., Hao, C., Tumor necrosis factor-related apoptosis-inducing signaling complex and its modulation by c-Flip and PED/PEA-15 in glioma cells (2002) J. Biol. Chem., 277 (28), pp. 25020-25025
Condorelli, G., Trencia, A., Vigliotta, G., Perfetti, A., Goglia, U., Cassese, A., Musti, A.M., Beguinot, F., Multiple members of the mitogen-activated protein kinase family are necessary for PED/PEA15 anti-apoptotic function (2002) J. Biol. Chem., 277, pp. 11013-11018
Johnsson, B., Lofas, S., Lindquist, G., Immobilization of proteins to a carboxylmethyl dextran modified gold surface for biospecific interaction analysis in SPR sensors (1991) Anal. Biochem., 198, pp. 268-277
Hill, J.M., Vaidyanathan, H., Ramos, J.W., Ginsberg, M.H., Werner, M.H., Recognition of ERK MAP kinase by PEA-15 reveals a common docking site within the death domain and death effector domain (2002) EMBO J., 21, pp. 6494-6504
PLD's (Phospholipases D) are ubiquitously expressed proteins involved in many transphosphatidylation reactions. They have a bi-lobed structure composed by two similar domains which at their interface reconstitute the catalytic site through the association of the two conserved HxKx4Dx6GSxN motifs. PLD1 interacts with the small phosphoprotein PED-PEA15 by an unknown mechanism that, by enhancing PLD1 stability, apparently increases its enzymatic activity; the minimum interacting region of PLD1 was previously identified as spanning residues 712-1074 (D4 region). Since the D4/PED-PEA15 interaction has been claimed to be one of the multiple molecular events that can trigger type 2 diabetes, we purified the two recombinant proteins to study in vitro this binding by both ELISA and SPR techniques. Whilst PED-PEA15 was easily expressed and purified, expression of recombinant D4 was more problematic and only the fusion protein with Thioredoxin A and a six Histidine Tag (Trx-His6-D4) demonstrated sufficient stability for further characterization. We have found that Trx-His6-D4 is present as two different oligomeric forms, though only the monomeric variant is able to interact with PED-PEA15. All these findings may have important implications for both the mechanisms of phospholipase activity and PED-PEA15 regulative functions. © 2008 Elsevier Inc. All rights reserved.
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Impact Factor: 4.859
Dettagli Esporta in BibTeX Esporta in EndNote
Scognamiglio PL, Doti N, Grieco P, Pedone C, Ruvo M, Marasco D
* Discovery Of Small Peptide Antagonists Of Ped/Pea15-D4alpha Interaction From Simplified Combinatorial Libraries (236 visite)
Chem Biol Drug Des Chemical Biology And Drug Design (ISSN: 1747-0277, 1747-0285), 2011 May; 77(5): 319-327.
Impact Factor: 2.282
Dettagli Esporta in BibTeX Esporta in EndNote
Correale S, Pirone L, Di Marcotullio L, De Smaele E, Greco A, Mazzà D, Moretti M, Alterio V, Vitagliano L, Di Gaetano S, Gulino A, Pedone E
* Molecular organization of the cullin E3 ligase adaptor KCTD11 (197 visite)
Biochimie (ISSN: 0300-9084, 1638-6183, 1638-6183electronic), 2011 Apr; 93(4): 715-724.
Impact Factor: 3.022
Dettagli Esporta in BibTeX Esporta in EndNote
Lanzillo R, Orefice G, Prinster A, Ventrella G, Liuzzi R, Scarano V, Florio C, Vacca G, Brunetti A, Alfano B, Brescia Morra V, Bonavita V
* Predictive factors of neutralizing antibodies development in relapsing-remitting multiple sclerosis patients on interferon Beta-1b therapy (120 visite) (PDF 137 visite)
Neurol Sci (ISSN: 1590-1874, 1590-3478), 2011 Apr; 32(2): 287-292.
Impact Factor: 1.315
Dettagli Esporta in BibTeX Esporta in EndNote
Ruggiero A, Squeglia F, Pirone L, Correale S, Berisio R
* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a major fragment of the resuscitation-promoting factor RpfB from Mycobacterium tuberculosis (179 visite)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2011 Jan 1; 67(1): 164-168.
Impact Factor: 0.506
Dettagli Esporta in BibTeX Esporta in EndNote
Farina B, Pirone L, Russo L, Viparelli F, Doti N, Pedone C, Pedone E, Fattorusso R
* NMR backbone dynamics studies of human PED/PEA-15 outline protein functional sites (278 visite)
Febs J (ISSN: 1742-4658, 1742-464x, 1742-4658electronic), 2010 Oct; 277(20): 4229-4240.
Impact Factor: 3.129
Dettagli Esporta in BibTeX Esporta in EndNote
Doti N, Cassese A, Marasco D, Paturzo F, Sabatella M, Viparelli F, Dathan N, Monti SM, Miele C, Formisano P, Beguinot F, Ruvo M
* Residues 762-801 of PLD1 mediate the interaction with PED/PEA15 (173 visite)
Mol Biosyst (ISSN: 1742-206x), 2010 Oct; 6(10): 2039-2048.
Impact Factor: 3.825
Dettagli Esporta in BibTeX Esporta in EndNote
Berisio R, Ruggiero A, Vitagliano L
* Elongation Factors Efia And Ef-Tu: Their Role In Translation And Beyond (182 visite)
Israel Journal Of Chemistry, 2010 Jun; 50(1): 71-79.
Impact Factor: 2.561
Dettagli Esporta in BibTeX Esporta in EndNote
Ruggiero A, Squeglia F, Esposito C, Marasco D, Pedone E, Pedone C, Berisio R
* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of the resuscitation promoting factor interacting protein RipA from M. tuberculosis (153 visite)
Protein Pept Lett (ISSN: 0929-8665, 1875-5305), 2010 Jan; 17(1): 70-73.
Impact Factor: 1.849
Dettagli Esporta in BibTeX Esporta in EndNote
Di Stasi R, Diana D, Capasso D, Palumbo R, Romanelli A, Pedone C, Fattorusso R, D'Andrea LD
* VEGFR1(D2) in drug discovery: Expression and molecular characterization (153 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2010; 94(6): 800-809.
Impact Factor: 2.572
Dettagli Esporta in BibTeX Esporta in EndNote
Sandomenico A, Monti SM, Sabatella M, De Capua A, Tornatore L, Doti N, Viparelli F, Dathan NA, Pedone C, Ruvo M, Marasco D
* Protein-protein interactions: a simple strategy to identify binding sites and peptide antagonists (205 visite)
Chem Biol Drug Des Chemical Biology And Drug Design (ISSN: 1747-0285, 1747-0277), 2009 May; 73(5): 483-493.
Impact Factor: 2.473
Dettagli Esporta in BibTeX Esporta in EndNote
Vitagliano L, Ruggiero A, Pedone C, Berisio R
* Molecular dynamics studies of the P pilus rod subunit PapA (228 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 192-199.
Impact Factor: 1.807
Dettagli Esporta in BibTeX Esporta in EndNote
Wekselman I, Davidovich C, Agmon I, Zimmerman E, Rozenberg H, Bashan A, Berisio R, Yonath A
* Ribosome's mode of function: Myths, facts and recent results (154 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 122-130.
Impact Factor: 1.807
Dettagli Esporta in BibTeX Esporta in EndNote
Viparelli F, Doti N, Monti SM, Marasco D, Dathan N, Pedone C, Miele C, Formisano P, Beguinot F, Ruvo M
* Peptide antagonists of the PED-hPLD1 binding (158 visite)
Adv Exp Med Biol (ISSN: 0065-2598, 0065-2598print, 0065-2598linking), 2009; 611: 445-446.
Impact Factor: 2.02
Dettagli Esporta in BibTeX Esporta in EndNote
Merlino A, Varriale S, Coscia MR, Mazzarella L, Oreste U
* Structure and dimerization of the teleost transmembrane immunoglobulin region (187 visite)
Journal Of Molecular Graphics & Modelling (ISSN: 1093-3263), 2008 Oct; 27(3): 401-407.
Impact Factor: 2.347
Dettagli Esporta in BibTeX Esporta in EndNote
Vitagliano L, Ruggiero A, Pedone C, Berisio R
* Conformational states and association mechanism of Yersinia pestis Caf1 subunits (143 visite)
Biochem Biophys Res Commun (ISSN: 0006-291x, 1090-2104, 1090-2104electronic), 2008 Sep 8; 372(4): 804-810.
Impact Factor: 2.648
Dettagli Esporta in BibTeX Esporta in EndNote
Viparelli F, Cassese A, Doti N, Paturzo F, Marasco D, Dathan NA, Monti SM, Basile G, Ungaro P, Sabatella M, Miele C, Teperino R, Consiglio E, Pedone C, Beguinot F, Formisano P, Ruvo M
* Targeting of PED/PEA-15 molecular interaction with phospholipase D1 enhances insulin sensitivity in skeletal muscle cells (203 visite)
J Biol Chem (ISSN: 0021-9258, 1083-351x), 2008 Sep 1; 283(31): 21769-21778.
Impact Factor: 5.52
Dettagli Esporta in BibTeX Esporta in EndNote
Ruvo M, Marasco D, Viparelli F, Tornatore L, Sandomenico A, Doti N, Pedone C, Benedetti E, Monti SM
* Peptide antagonists of protein-protein interactions identified by screening protein fragments derived by enzyme degradation (154 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2008 Sep; 14(8): N/D-N/D.
Impact Factor: 1.654
Dettagli Esporta in BibTeX Esporta in EndNote
Tornatore L, Marasco D, Dathan N, Vitale RM, Benedetti E, Papa S, Franzoso G, Ruvo M, Monti SM
* Gadd45 beta forms a homodimeric complex that binds tightly to MKK7 (235 visite)
J Mol Biol (ISSN: 0022-2836, 0022-2283, 1089-8638), 2008 Apr 18; 378(1): 97-111.
Impact Factor: 5.673
Dettagli Esporta in BibTeX Esporta in EndNote
Hilvo M, Innocenti A, Monti SM, De Simone G, Supuran CT, Parkkila S
* Recent advances in research on the most novel carbonic anhydrases, CA XIII and XV (164 visite)
Curr Pharm Des Current Pharmaceutical Design (ISSN: 1381-6128, 1873-4286), 2008; 14(7): 672-678.
Impact Factor: 4.399
Dettagli Esporta in BibTeX Esporta in EndNote
Ruggiero A, Tizzano B, Geerlof A, Pedone E, Pedone C, Wilmanns M, Berisio R
* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a resuscitation-promoting factor from Mycobacterium tuberculosis (162 visite)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2007 Oct 1; 63(10): 870-873.
Impact Factor: 0.645
Dettagli Esporta in BibTeX Esporta in EndNote
Vitagliano L, Ruggiero A, Pedone C, Berisio R
* A Molecular Dynamics Study of Pilus Subunits: Insights into Pilus Biogenesis (199 visite)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2007 Apr 6; 367(4): 935-941.
Impact Factor: 4.472
Dettagli Esporta in BibTeX Esporta in EndNote
Galdiero S, Galdiero M, Pedone C
* Beta-Barrel Membrane Bacterial Proteins: Structure, Function, Assembly And Interaction With Lipids (134 visite)
Curr Protein Pept Sci (ISSN: 1389-2037), 2007 Feb; 8(1): 63-82.
Impact Factor: 3.259
Dettagli Esporta in BibTeX Esporta in EndNote
Chiechio S, Copani A, Gereau R, Nicoletti F
* Acetyl-l-carnitine in neuropathic pain (117 visite)
Cns Drugs (ISSN: 1172-7047), 2007; 21: 38-38.
Impact Factor: 4.514
Dettagli Esporta in BibTeX Esporta in EndNote
Del Gatto A, Zaccaro L, Grieco P, Novellino E, Zannetti A, Del Vecchio S, Iommelli F, Salvatore M, Pedone C, Saviano M
* Novel And Selective Alpha (v) Beta3 Receptor Peptide Antagonist: Design, Synthesis, And Biological Behavior (295 visite)
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2006 Jun 1; 49(11): 3416-3420.
Impact Factor: 5.115
Dettagli Esporta in BibTeX Esporta in EndNote
Amit M, Berisio R, Baram D, Harms J, Bashan A, Yonath A
* A crevice adjoining the ribosome tunnel: Hints for cotranslational folding (184 visite)
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 2005 Jun 13; 579(15): 3207-3213.
Impact Factor: 3.415
Dettagli Esporta in BibTeX Esporta in EndNote
Rivieccio V, Mannini R, Concilio L, D'Auria S, Pedone C, Grimaldi G
* Expression, purification and partial characterization of the Krüppel-associated box (KRAB) from the human ZNF2 protein (134 visite)
Protein Pept Lett (ISSN: 0929-8665, 1875-5305), 2005; 12(6): 527-532.
Impact Factor: 0.84
Dettagli Esporta in BibTeX Esporta in EndNote
Giacco R, Clemente G, Luongo D, Lasorella G, Fiume I, Brouns F, Bornet F, Patti L, Cipriano P, Rivellese AA, Riccardi G
* Effects of short-chain fructo-oligosaccharides on glucose and lipid metabolism in mild hypercholesterolaemic individuals (182 visite)
Clin Nutr (ISSN: 0261-5614), 2004 Jun; 23(3): 331-340.
Impact Factor: 2.019
Dettagli Esporta in BibTeX Esporta in EndNote
Cortesi R, Mischiati C, Borgatti M, Breda L, Romanelli A, Saviano M, Pedone C, Gambari R, Nastruzzi C
* Formulations for natural and peptide nucleic acids based on cationic polymeric submicron particles (191 visite)
The Aaps Journal (ISSN: 1522-1059, 1550-7416), 2004 Jan 20; 6(1): N/D-N/D.
Impact Factor: 1.938
Dettagli Esporta in BibTeX Esporta in EndNote
Zarivach R, Bashan A, Berisio R, Harms J, Auerbach T, Schluenzen F, Bartels H, Baram D, Pyetan E, Sittner A, Amit M, Hansen HAS, Kessler M, Liebe C, Wolff A, Agmon I, Yonath A
* Functional aspects of ribosomal architecture: Symmetry, chirality and regulation (167 visite)
J Phys Org Chem (ISSN: 0894-3230), 2004; 17(11): 901-912.
Impact Factor: 1.211
Dettagli Esporta in BibTeX Esporta in EndNote
Musumeci D, Roviello GN, Valente M, Sapio R, Pedone C, Bucci EM
* New synthesis of PNA-3′DNA linker monomers, useful building blocks to obtain PNA/DNA chimeras (179 visite)
Biopolymers, 2004; 76(6): 535-542.
Impact Factor: 2.248
Dettagli Esporta in BibTeX Esporta in EndNote
Mansi R, Tesauro D, De Capua A, Fattorusso R, Carac C, Aloj L, Benedetti E, Morelli G
* Peptide-chelating agent conjugate for selective targeting of somatostatin receptor type 1: Synthesis and characterization (230 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2004; 76(6): 527-534.
Impact Factor: 2.863
Dettagli Esporta in BibTeX Esporta in EndNote
Sorrentino N, De Simone G, Menchise V, Mandrich L, Rossi M, Manco G, Pedone C
* Crystallization and preliminary X-ray diffraction studies of Aes acetyl-esterase from Escherichia coli (142 visite)
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2003 Oct; 59(10): 1846-1848.
Impact Factor: 2.208
Dettagli Esporta in BibTeX Esporta in EndNote
Bashan A, Zarivach R, Schluenzen F, Agmon I, Harms J, Auerbach T, Baram D, Berisio R, Bartels H, Hansen HAS, Fucini P, Wilson D, Peretz M, Kessler M, Yonath A
* Ribosomal crystallography: Peptide bond formation and its inhibition (214 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2003 Sep; 70(1): 19-41.
Impact Factor: 2.733
Dettagli Esporta in BibTeX Esporta in EndNote
Berisio R, Schluenzen F, Harms J, Bashan A, Auerbach T, Baram D, Yonath A
* Structural insight into the role of the ribosomal tunnel in cellular regulation (148 visite)
Nat Struct Biol (ISSN: 1072-8368), 2003 May; 10(5): 366-370.
Impact Factor: 11.579
Dettagli Esporta in BibTeX Esporta in EndNote
Isernia C, Bucci E, Leone M, Zaccaro L, Di Lello P, Digilio G, Esposito S, Saviano M, Di Blasio B, Pedone C, Pedone PV, Fattorusso R
* NMR structure of the single QALGGH zinc finger domain from the Arabidopsis thaliana SUPERMAN protein (212 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2003 Mar 3; 4(2-3): 171-180.
Impact Factor: 3.992
Dettagli Esporta in BibTeX Esporta in EndNote
Bashan A, Agmon I, Zarivach R, Schluenzen F, Harms J, Berisio R, Bartels H, Franceschi F, Auerbach T, Hansen HAS, Kossoy E, Kessler M, Yonath A
* Structural basis of the ribosomal machinery for peptide bond formation, translocation, and nascent chain progression (191 visite)
Mol Cell (ISSN: 1097-2765, 1097-4164), 2003 Jan; 11(1): 91-102.
Impact Factor: 16.835
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Peggion C, Formaggio F, Crisma M, Toniolo C, Jimenez AI, Cativiela C, Kaptein B, Broxterman QB, Saviano M, Benedetti E
* Folding of peptides characterized by c3Val, a highly constrained analogue of valine (218 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2003; 68(2): 178-191.
Impact Factor: 2.733
Dettagli Esporta in BibTeX Esporta in EndNote
Fassina G, Ruvo M, Palombo G, Verdoliva A, Marino M
* Novel ligands for the affinity-chromatographic purification of antibodies (220 visite)
J Biochem Biophys Methods (ISSN: 0165-022x, 0165-022xlinking), 2001 Oct 30; 49(1-3): 481-490.
Impact Factor: 1.218
Dettagli Esporta in BibTeX Esporta in EndNote
De Falco S, Ruvoletto MG, Verdoliva A, Ruvo M, Raucci A, Marino M, Senatore S, Cassani G, Alberti A, Pontisso P, Fassina G
* Cloning and Expression of a Novel Hepatitis B Virus-binding Protein from HepG2 Cells (207 visite)
J Biol Chem (ISSN: 0021-9258, 1083-351x), 2001 Sep 28; 276(39): 36613-36623.
Impact Factor: 7.258
Dettagli Esporta in BibTeX Esporta in EndNote
Romanelli A, Garella I, Menchise V, Iacovino R, Saviano M, Montesarchio D, Didierjean C, Lello PD, Rossi F, Benedetti E
* Crystal-state conformation of Cα, α-dialkylated peptides containing chiral β-homo-residues (211 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2001; 7(1): 15-26.
Impact Factor: 1.451
Dettagli Esporta in BibTeX Esporta in EndNote
Caraglia M, Tagliaferri P, Correale P, Genua G, Pinto A, Del Vecchio S, Esposito G, Bianco AR
Cytosine arabinoside increases the binding of 125I-labelled epidermal growth factor and 125I-transferrin and enhances the in vitro targeting of human tumour cells with anti-(growth factor receptor) mAb (32 visite)
Cancer Immunol Immunother (ISSN: 0340-7004linking), 1993 Aug; 37 (3 ): 150-156.
Impact Factor: 4.293
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Oliva A, Della Ragione F, Fratta M, Marrone G, Palumbo R, Zappia V
Effect of retinoic acid on osteocalcin gene expression in human osteoblasts (102 visite)
Biochem Biophys Res Commun (ISSN: 0006-291xprint, 0006-291xlinking), 1993 Mar 31; 191(3): 908-914.
Impact Factor: 2.671
Dettagli Esporta in BibTeX Esporta in EndNote
Oliva A, Marrone G, Della Ragione F, Riccio V, Palumbo R, Rossano F, Zappia V
Isolation and characterization of human embryonic osteoblasts (129 visite)
Calcif Tissue Int (ISSN: 0171-967xprint, 0171-967xlinking), 1992 Nov; 51(5): 356-362.
Impact Factor: 2.364
Dettagli Esporta in BibTeX Esporta in EndNote
Margotta V, Fonti R, Palladini G, Filoni S, Lauro GM
Transient expression of glial-fibrillary acidic protein (GFAP) in the ependyma of the regenerating spinal cord in adult newts (123 visite)
Journal Fur Hirnforschung (ISSN: 0021-8359), 1991; 32(4): 485-490.
Impact Factor: 0
Dettagli Esporta in BibTeX Esporta in EndNote
78 Records (73 escludendo Abstract e Conferenze).
Impact factor totale: 264.373 (247.36 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 279.216 (259.719 escludendo Abstract e Conferenze).
Impact factor totale: 264.373 (247.36 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 279.216 (259.719 escludendo Abstract e Conferenze).
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Ultima modifica di Marco Comerci in data Thursday 19 March 2015, 13:05:49
185 visite. Ultima visita in data Tuesday 10 December 2019, 10:50:35
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