Liver fat in obesity: role of type 2 diabetes mellitus and adipose tissue distribution (156 visite)
Eur J Clin Invest (ISSN: 0014-2972, 1365-2362), 2011 Jan; 41(1): 39-44.
Tipo di articolo: Letter, Journal Article,
Impact factor: 3.018, Impact factor a 5 anni: 2.797
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-0022135321&partnerID=40&md5=bd8bcc7356106c9be31064fb180f138b
Parole chiave: Female, Human, Letter, Liver Disease, Obesity, Adipose Tissue Physiopathology, Adult, Aged, Blood Glucose Metabolism, Body Mass Index, Case-Control Studies, Diabetes Mellitus, Type 2 Blood Physiopathology, Fatty Liver Physiopathology, Glucose Clamp Technique, Insulin Blood, Insulin Resistance Physiology, Intra-Abdominal Fat Metabolism Physiopathology, Middle Aged, Obesity Blood Physiopathology, Triglycerides Blood Metabolism, Fat Distribution, Insulin-Resistance, Liver Fat, Subcutaneous Fat, Type 2 Diabetes, Hemoglobin A1c, Metformin, Triacylglycerol, Article, Body Fat Distribution, Clinical Article, Controlled Study, Glycemic Control, Hyperinsulinemia, Insulin Sensitivity, Intraabdominal Fat, Non Insulin Dependent Diabetes Mellitus, Nuclear Magnetic Resonance Imaging, Priority Journal, Proton Nuclear Magnetic Resonance, Waist Circumference,
Affiliazioni:
*** IBB - CNR ***
Department of Medicine, University of Naples, Naples, Italy
Department of Metabolic Diseases, University of Naples, Naples, Italy
Department of Gastroenterology, University of Naples, Naples, Italy
Department of Clinical and Experimental Medicine, Federico II University, Naples, Italy.
Institute of Biostructure and Bioimage, National Research Council, Naples, Italy
SDN Foundation, Institute of Diagnostic and Nuclear Development, Naples, Italy
Institute of Food Sciences, National Research Council, Avellino, Italy
Department of Biomorphological and Functional Science, Federico II University, Naples, Italy
Riferimenti:
Bellentani, S., Saccoccio, G., Masutti, F., Croce, L.S., Brandi, G., Sasso, F., Prevalence of and risk factors for hepatic steatosis in Northern Italy (2000) Ann Intern Med, 132, pp. 112-11
Luyckx, F.H., Desaive, C., Thiry, A., Dewe, W., Scheen, A.J., Gielen, J.E., Liver abnormalities in severely obese subjects: effect of drastic weight loss after gastroplasty (1998) Int J Obes Relat Metab Disord, 22, pp. 222-226
Gastaldelli, A., Cusi, K., Pettiti, M., Hardies, J., Miyazaki, Y., Berria, R., Relationship between hepatic/visceral fat and hepatic insulin resistance in nondiabetic and type 2 diabetic subjects (2007) Gastroenterology, 133, pp. 496-506
Bugianesi, E., McCullough, A.J., Marchesini, G., Insulin resistance: a metabolic pathway to chronic liver disease (2005) Hepatology, 42, pp. 987-1000
Cnop, M., Landchild, M.J., Vidal, J., Havel, P.J., Knowles, N.G., Carr, D.R., The concurrent accumulation of intra-abdominal and subcutaneous fat explains the association between insulin resistance and plasma leptin concentrations: distinct metabolic effects of two fat compartments (2002) Diabetes, 51, pp. 1005-1015
Ross, R., Aru, J., Freeman, J., Hudson, R., Janssen, I., Abdominal adiposity and insulin resistance in obese men (2002) Am J Physiol Endocrinol Metab, 282, pp. E657-E663
Marchesini, G., Brizi, M., Morselli-Labate, A.M., Bianchi, G., Bugianesi, E., McCullough, A.J., Association of nonalcoholic fatty liver disease with insulin resistance (1999) Am J Med, 107, pp. 450-455
Seppala-Lindroos, A., Vehkavaara, S., Hakkinen, A.M., Goto, T., Westerbacka, J., Sovijarvi, A., Fat accumulation in the liver is associated with defects in insulin suppression of glucose production and serum free fatty acids independent of obesity in normal men (2002) J Clin Endocrinol Metab, 87, pp. 3023-3028
Venturi, C., Zoppini, G., Zamboni, C., Muggeo, M., Insulin sensitivity and hepatic steatosis in obese subjects with normal glucose tolerance (2004) Nutr Metab Cardiovasc Dis, 14, pp. 200-204
Silverman, J.F., O'Brien, K.F., Long, S., Leggett, N., Khazanie, P.G., Pories, W.J., Liver pathology in morbidly obese patients with and without diabetes (1990) Am J Gastroenterol, 85, pp. 1349-1355
Kelley, D.E., McKolanis, T.M., Hegazi, R.A., Kuller, L.H., Kalhan, S.C., Fatty liver in type 2 diabetes mellitus: relation to regional adiposity, fatty acids, and insulin resistance (2003) Am J Physiol Endocrinol Metab, 285, pp. E906-E916
Kotronen, A., Juurinen, L., Hakkarainen, A., Westerbacka, J., Corner, A., Bergholm, R., Liver fat is increased in type 2 diabetic patients and underestimated by serum alanine aminotransferase compared with equally obese nondiabetic subjects (2008) Diabetes Care, 31, pp. 165-169
Gallagher, D., Kelley, D.E., Yim, J.E., Spence, N., Albu, J., Boxt, L., Adipose tissue distribution is different in type 2 diabetes (2009) Am J Clin Nutr, 89, pp. 807-814
Longo, R., Pollesello, P., Ricci, C., Masutti, F., Kvam, B.J., Bercich, L., Proton MR spectroscopy in quantitative in vivo determination of fat content in human liver steatosis (1995) J Magn Reson Imaging, 5, pp. 281-285
Longo, R., Ricci, C., Masutti, F., Vidimari, R., Croce, L.S., Bercich, L., Fatty infiltration of the liver. Quantification by 1H localized magnetic resonance spectroscopy and comparison with computed tomography (1993) Invest Radiol, 28, pp. 297-302
Ryysy, L., Hakkinen, A.M., Goto, T., Vehkavaara, S., Westerbacka, J., Halavaara, J., Hepatic fat content and insulin action on free fatty acids and glucose metabolism rather than insulin absorption are associated with insulin requirements during insulin therapy in type 2 diabetic patients (2000) Diabetes, 49, pp. 749-758
DeFronzo, R.A., Tobin, J.D., Andres, R., Glucose clamp technique: a method for quantifying insulin secretion and resistance (1979) Am J Physiol, 237, pp. E214-E223
Palmeira, C.M., Rolo, A.P., Berthiaume, J., Bjork, J.A., Wallace, K.B., Hyperglycemia decreases mitochondrial function: the regulatory role of mitochondrial biogenesis (2007) Toxicol Appl Pharmacol, 225, pp. 214-220
Caldwell, S.H., Swerdlow, R.H., Khan, E.M., Iezzoni, J.C., Hespenheide, E.E., Parks, J.K., Mitochondrial abnormalities in non-alcoholic steatohepatitis (1999) J Hepatol, 31, pp. 430-434
Demeilliers, C., Maisonneuve, C., Grodet, A., Mansouri, A., Nguyen, R., Tinel, M., Impaired adaptive resynthesis and prolonged depletion of hepatic mitochondrial DNA after repeated alcohol binges in mice (2002) Gastroenterology, 123, pp. 1278-1290
Bugianesi, E., Gastaldelli, A., Vanni, E., Gambino, R., Cassader, M., Baldi, S., Insulin resistance in non-diabetic patients with non-alcoholic fatty liver disease: sites and mechanisms (2005) Diabetologia, 48, pp. 634-642
Korenblat, K.M., Fabbrini, E., Mohammed, B.S., Klein, S., Liver, muscle, and adipose tissue insulin action is directly related to intrahepatic triglyceride content in obese subjects (2008) Gastroenterology, 134, pp. 1369-1375
Kotronen, A., Westerbacka, J., Bergholm, R., Pietilainen, K.H., Yki-Jarvinen, H., Liver fat in the metabolic syndrome (2007) J Clin Endocrinol Metab, 92, pp. 3490-3497
Tushuizen, M.E., Bunck, M.C., Pouwels, P.J., Bontemps, S., Mari, A., Diamant, M., Lack of association of liver fat with model parameters of beta-cell function in men with impaired glucose tolerance and type 2 diabetes (2008) Eur J Endocrinol, 159, pp. 251-257
Weyer, C., Foley, J.E., Bogardus, C., Tataranni, P.A., Pratley, R.E., Enlarged subcutaneous abdominal adipocyte size, but not obesity itself, predicts type II diabetes independent of insulin resistance (2000) Diabetologia, 43, pp. 1498-1506
Dubois, S.G., Heilbronn, L.K., Smith, S.R., Albu, J.B., Kelley, D.E., Ravussin, E., Decreased expression of adipogenic genes in obese subjects with type 2 diabetes (2006) Obesity (Silver Spring), 14, pp. 1543-1552
Kim, J.Y., Van De Wall, E., Laplante, M., Azzara, A., Trujillo, M.E., Hofmann, S.M., Obesity-associated improvements in metabolic profile through expansion of adipose tissue (2007) J Clin Invest, 117, pp. 2621-2637
Luyckx, F. H., Desaive, C., Thiry, A., Dewe, W., Scheen, A. J., Gielen, J. E., Liver abnormalities in severely obese subjects: effect of drastic weight loss after gastroplasty (1998) Int J Obes Relat Metab Disord, 22, pp. 222-226
Silverman, J. F., O'Brien, K. F., Long, S., Leggett, N., Khazanie, P. G., Pories, W. J., Liver pathology in morbidly obese patients with and without diabetes (1990) Am J Gastroenterol, 85, pp. 1349-1355
Kelley, D. E., McKolanis, T. M., Hegazi, R. A., Kuller, L. H., Kalhan, S. C., Fatty liver in type 2 diabetes mellitus: relation to regional adiposity, fatty acids, and insulin resistance (2003) Am J Physiol Endocrinol Metab, 285, pp. E906-E916
DeFronzo, R. A., Tobin, J. D., Andres, R., Glucose clamp technique: a method for quantifying insulin secretion and resistance (1979) Am J Physiol, 237, pp. E214-E223
Palmeira, C. M., Rolo, A. P., Berthiaume, J., Bjork, J. A., Wallace, K. B., Hyperglycemia decreases mitochondrial function: the regulatory role of mitochondrial biogenesis (2007) Toxicol Appl Pharmacol, 225, pp. 214-220
Caldwell, S. H., Swerdlow, R. H., Khan, E. M., Iezzoni, J. C., Hespenheide, E. E., Parks, J. K., Mitochondrial abnormalities in non-alcoholic steatohepatitis (1999) J Hepatol, 31, pp. 430-434
Korenblat, K. M., Fabbrini, E., Mohammed, B. S., Klein, S., Liver, muscle, and adipose tissue insulin action is directly related to intrahepatic triglyceride content in obese subjects (2008) Gastroenterology, 134, pp. 1369-1375
Tushuizen, M. E., Bunck, M. C., Pouwels, P. J., Bontemps, S., Mari, A., Diamant, M., Lack of association of liver fat with model parameters of beta-cell function in men with impaired glucose tolerance and type 2 diabetes (2008) Eur J Endocrinol, 159, pp. 251-257
Dubois, S. G., Heilbronn, L. K., Smith, S. R., Albu, J. B., Kelley, D. E., Ravussin, E., Decreased expression of adipogenic genes in obese subjects with type 2 diabetes (2006) Obesity (Silver Spring), 14, pp. 1543-1552
Kim, J. Y., Van De Wall, E., Laplante, M., Azzara, A., Trujillo, M. E., Hofmann, S. M., Obesity-associated improvements in metabolic profile through expansion of adipose tissue (2007) J Clin Invest, 117, pp. 2621-2637
Eur J Clin Invest (ISSN: 0014-2972, 1365-2362), 2011 Jan; 41(1): 39-44.
Tipo di articolo: Letter, Journal Article,
Impact factor: 3.018, Impact factor a 5 anni: 2.797
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-0022135321&partnerID=40&md5=bd8bcc7356106c9be31064fb180f138b
Parole chiave: Female, Human, Letter, Liver Disease, Obesity, Adipose Tissue Physiopathology, Adult, Aged, Blood Glucose Metabolism, Body Mass Index, Case-Control Studies, Diabetes Mellitus, Type 2 Blood Physiopathology, Fatty Liver Physiopathology, Glucose Clamp Technique, Insulin Blood, Insulin Resistance Physiology, Intra-Abdominal Fat Metabolism Physiopathology, Middle Aged, Obesity Blood Physiopathology, Triglycerides Blood Metabolism, Fat Distribution, Insulin-Resistance, Liver Fat, Subcutaneous Fat, Type 2 Diabetes, Hemoglobin A1c, Metformin, Triacylglycerol, Article, Body Fat Distribution, Clinical Article, Controlled Study, Glycemic Control, Hyperinsulinemia, Insulin Sensitivity, Intraabdominal Fat, Non Insulin Dependent Diabetes Mellitus, Nuclear Magnetic Resonance Imaging, Priority Journal, Proton Nuclear Magnetic Resonance, Waist Circumference,
Affiliazioni:
*** IBB - CNR ***
Department of Medicine, University of Naples, Naples, Italy
Department of Metabolic Diseases, University of Naples, Naples, Italy
Department of Gastroenterology, University of Naples, Naples, Italy
Department of Clinical and Experimental Medicine, Federico II University, Naples, Italy.
Institute of Biostructure and Bioimage, National Research Council, Naples, Italy
SDN Foundation, Institute of Diagnostic and Nuclear Development, Naples, Italy
Institute of Food Sciences, National Research Council, Avellino, Italy
Department of Biomorphological and Functional Science, Federico II University, Naples, Italy
Riferimenti:
Bellentani, S., Saccoccio, G., Masutti, F., Croce, L.S., Brandi, G., Sasso, F., Prevalence of and risk factors for hepatic steatosis in Northern Italy (2000) Ann Intern Med, 132, pp. 112-11
Luyckx, F.H., Desaive, C., Thiry, A., Dewe, W., Scheen, A.J., Gielen, J.E., Liver abnormalities in severely obese subjects: effect of drastic weight loss after gastroplasty (1998) Int J Obes Relat Metab Disord, 22, pp. 222-226
Gastaldelli, A., Cusi, K., Pettiti, M., Hardies, J., Miyazaki, Y., Berria, R., Relationship between hepatic/visceral fat and hepatic insulin resistance in nondiabetic and type 2 diabetic subjects (2007) Gastroenterology, 133, pp. 496-506
Bugianesi, E., McCullough, A.J., Marchesini, G., Insulin resistance: a metabolic pathway to chronic liver disease (2005) Hepatology, 42, pp. 987-1000
Cnop, M., Landchild, M.J., Vidal, J., Havel, P.J., Knowles, N.G., Carr, D.R., The concurrent accumulation of intra-abdominal and subcutaneous fat explains the association between insulin resistance and plasma leptin concentrations: distinct metabolic effects of two fat compartments (2002) Diabetes, 51, pp. 1005-1015
Ross, R., Aru, J., Freeman, J., Hudson, R., Janssen, I., Abdominal adiposity and insulin resistance in obese men (2002) Am J Physiol Endocrinol Metab, 282, pp. E657-E663
Marchesini, G., Brizi, M., Morselli-Labate, A.M., Bianchi, G., Bugianesi, E., McCullough, A.J., Association of nonalcoholic fatty liver disease with insulin resistance (1999) Am J Med, 107, pp. 450-455
Seppala-Lindroos, A., Vehkavaara, S., Hakkinen, A.M., Goto, T., Westerbacka, J., Sovijarvi, A., Fat accumulation in the liver is associated with defects in insulin suppression of glucose production and serum free fatty acids independent of obesity in normal men (2002) J Clin Endocrinol Metab, 87, pp. 3023-3028
Venturi, C., Zoppini, G., Zamboni, C., Muggeo, M., Insulin sensitivity and hepatic steatosis in obese subjects with normal glucose tolerance (2004) Nutr Metab Cardiovasc Dis, 14, pp. 200-204
Silverman, J.F., O'Brien, K.F., Long, S., Leggett, N., Khazanie, P.G., Pories, W.J., Liver pathology in morbidly obese patients with and without diabetes (1990) Am J Gastroenterol, 85, pp. 1349-1355
Kelley, D.E., McKolanis, T.M., Hegazi, R.A., Kuller, L.H., Kalhan, S.C., Fatty liver in type 2 diabetes mellitus: relation to regional adiposity, fatty acids, and insulin resistance (2003) Am J Physiol Endocrinol Metab, 285, pp. E906-E916
Kotronen, A., Juurinen, L., Hakkarainen, A., Westerbacka, J., Corner, A., Bergholm, R., Liver fat is increased in type 2 diabetic patients and underestimated by serum alanine aminotransferase compared with equally obese nondiabetic subjects (2008) Diabetes Care, 31, pp. 165-169
Gallagher, D., Kelley, D.E., Yim, J.E., Spence, N., Albu, J., Boxt, L., Adipose tissue distribution is different in type 2 diabetes (2009) Am J Clin Nutr, 89, pp. 807-814
Longo, R., Pollesello, P., Ricci, C., Masutti, F., Kvam, B.J., Bercich, L., Proton MR spectroscopy in quantitative in vivo determination of fat content in human liver steatosis (1995) J Magn Reson Imaging, 5, pp. 281-285
Longo, R., Ricci, C., Masutti, F., Vidimari, R., Croce, L.S., Bercich, L., Fatty infiltration of the liver. Quantification by 1H localized magnetic resonance spectroscopy and comparison with computed tomography (1993) Invest Radiol, 28, pp. 297-302
Ryysy, L., Hakkinen, A.M., Goto, T., Vehkavaara, S., Westerbacka, J., Halavaara, J., Hepatic fat content and insulin action on free fatty acids and glucose metabolism rather than insulin absorption are associated with insulin requirements during insulin therapy in type 2 diabetic patients (2000) Diabetes, 49, pp. 749-758
DeFronzo, R.A., Tobin, J.D., Andres, R., Glucose clamp technique: a method for quantifying insulin secretion and resistance (1979) Am J Physiol, 237, pp. E214-E223
Palmeira, C.M., Rolo, A.P., Berthiaume, J., Bjork, J.A., Wallace, K.B., Hyperglycemia decreases mitochondrial function: the regulatory role of mitochondrial biogenesis (2007) Toxicol Appl Pharmacol, 225, pp. 214-220
Caldwell, S.H., Swerdlow, R.H., Khan, E.M., Iezzoni, J.C., Hespenheide, E.E., Parks, J.K., Mitochondrial abnormalities in non-alcoholic steatohepatitis (1999) J Hepatol, 31, pp. 430-434
Demeilliers, C., Maisonneuve, C., Grodet, A., Mansouri, A., Nguyen, R., Tinel, M., Impaired adaptive resynthesis and prolonged depletion of hepatic mitochondrial DNA after repeated alcohol binges in mice (2002) Gastroenterology, 123, pp. 1278-1290
Bugianesi, E., Gastaldelli, A., Vanni, E., Gambino, R., Cassader, M., Baldi, S., Insulin resistance in non-diabetic patients with non-alcoholic fatty liver disease: sites and mechanisms (2005) Diabetologia, 48, pp. 634-642
Korenblat, K.M., Fabbrini, E., Mohammed, B.S., Klein, S., Liver, muscle, and adipose tissue insulin action is directly related to intrahepatic triglyceride content in obese subjects (2008) Gastroenterology, 134, pp. 1369-1375
Kotronen, A., Westerbacka, J., Bergholm, R., Pietilainen, K.H., Yki-Jarvinen, H., Liver fat in the metabolic syndrome (2007) J Clin Endocrinol Metab, 92, pp. 3490-3497
Tushuizen, M.E., Bunck, M.C., Pouwels, P.J., Bontemps, S., Mari, A., Diamant, M., Lack of association of liver fat with model parameters of beta-cell function in men with impaired glucose tolerance and type 2 diabetes (2008) Eur J Endocrinol, 159, pp. 251-257
Weyer, C., Foley, J.E., Bogardus, C., Tataranni, P.A., Pratley, R.E., Enlarged subcutaneous abdominal adipocyte size, but not obesity itself, predicts type II diabetes independent of insulin resistance (2000) Diabetologia, 43, pp. 1498-1506
Dubois, S.G., Heilbronn, L.K., Smith, S.R., Albu, J.B., Kelley, D.E., Ravussin, E., Decreased expression of adipogenic genes in obese subjects with type 2 diabetes (2006) Obesity (Silver Spring), 14, pp. 1543-1552
Kim, J.Y., Van De Wall, E., Laplante, M., Azzara, A., Trujillo, M.E., Hofmann, S.M., Obesity-associated improvements in metabolic profile through expansion of adipose tissue (2007) J Clin Invest, 117, pp. 2621-2637
Luyckx, F. H., Desaive, C., Thiry, A., Dewe, W., Scheen, A. J., Gielen, J. E., Liver abnormalities in severely obese subjects: effect of drastic weight loss after gastroplasty (1998) Int J Obes Relat Metab Disord, 22, pp. 222-226
Silverman, J. F., O'Brien, K. F., Long, S., Leggett, N., Khazanie, P. G., Pories, W. J., Liver pathology in morbidly obese patients with and without diabetes (1990) Am J Gastroenterol, 85, pp. 1349-1355
Kelley, D. E., McKolanis, T. M., Hegazi, R. A., Kuller, L. H., Kalhan, S. C., Fatty liver in type 2 diabetes mellitus: relation to regional adiposity, fatty acids, and insulin resistance (2003) Am J Physiol Endocrinol Metab, 285, pp. E906-E916
DeFronzo, R. A., Tobin, J. D., Andres, R., Glucose clamp technique: a method for quantifying insulin secretion and resistance (1979) Am J Physiol, 237, pp. E214-E223
Palmeira, C. M., Rolo, A. P., Berthiaume, J., Bjork, J. A., Wallace, K. B., Hyperglycemia decreases mitochondrial function: the regulatory role of mitochondrial biogenesis (2007) Toxicol Appl Pharmacol, 225, pp. 214-220
Caldwell, S. H., Swerdlow, R. H., Khan, E. M., Iezzoni, J. C., Hespenheide, E. E., Parks, J. K., Mitochondrial abnormalities in non-alcoholic steatohepatitis (1999) J Hepatol, 31, pp. 430-434
Korenblat, K. M., Fabbrini, E., Mohammed, B. S., Klein, S., Liver, muscle, and adipose tissue insulin action is directly related to intrahepatic triglyceride content in obese subjects (2008) Gastroenterology, 134, pp. 1369-1375
Tushuizen, M. E., Bunck, M. C., Pouwels, P. J., Bontemps, S., Mari, A., Diamant, M., Lack of association of liver fat with model parameters of beta-cell function in men with impaired glucose tolerance and type 2 diabetes (2008) Eur J Endocrinol, 159, pp. 251-257
Dubois, S. G., Heilbronn, L. K., Smith, S. R., Albu, J. B., Kelley, D. E., Ravussin, E., Decreased expression of adipogenic genes in obese subjects with type 2 diabetes (2006) Obesity (Silver Spring), 14, pp. 1543-1552
Kim, J. Y., Van De Wall, E., Laplante, M., Azzara, A., Trujillo, M. E., Hofmann, S. M., Obesity-associated improvements in metabolic profile through expansion of adipose tissue (2007) J Clin Invest, 117, pp. 2621-2637
BACKGROUND: Fatty liver is commonly associated with insulin-resistant conditions, often related to increased abdominal visceral fat. Our objective was to elucidate the specific roles of obesity, type 2 diabetes mellitus, insulin-resistance and abdominal fat distribution.; MATERIALS AND METHODS: The study population comprised 13 diabetic obese (DO), 10 nondiabetic obese (NDO), and nine normal-weight control (C) men aged 28-65years, with normal plasma triglyceride levels. DO were in good glycaemic control (HbA1c = 6·8 ± 0·8%) (M ± SD) with diet (n = 8) or diet + metformin (n = 5). Liver fat content was measured by (1) H-magnetic resonance spectroscopy, abdominal fat distribution by magnetic resonance imaging and insulin sensitivity by hyperinsulinaemic euglycaemic clamp.; RESULTS: DO and NDO subjects had similar whole-body insulin resistance, BMI and waist circumference, higher than those of C subjects (P < 0·001). DO had more liver fat (11·9 ± 7·0%) than NDO (5·2 ± 2·8%, P < 0·05) and C (1·6 ± 1·0%, P < 0·001). Abdominal fat was greater in DO and NDO than in C (visceral: DO 3184 ± 843, NDO 2843 ± 1378 vs. C 1212 ± 587 cm(3), P < 0·001; subcutaneous: DO 4029 ± 362, NDO 5197 ± 1398 vs. C 2312 ± 626 cm(3), P < 0·001), visceral fat being not significantly different between the two obese groups, and subcutaneous fat significantly less in DO than in NDO (P < 0·05).; CONCLUSIONS: Type 2 diabetes is associated with increased fat accumulation in the liver, independent of obesity and whole-body insulin resistance. The increased liver fat in DO patients may be part of an altered regional fat distribution that includes an inadequate subcutaneous fat storing capacity, rather than simply being a consequence of increased abdominal visceral content. 2010 The Authors. European Journal of Clinical Investigation 2010 Stichting European Society for Clinical Investigation Journal Foundation.
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Tumminia A, Milluzzo A, Cinti F, Parisi M, Tata F, Frasca F, Frittitta L, Vigneri R, Sciacca L
* Abnormal 1-hour post-load glycemia during pregnancy impairs post-partum metabolic status: a single-center experience (63 visite)
J Endocrinol Invest (ISSN: 1720-8386, 0391-4097, 1720-8386electronic), 2017 Oct 24; N/D: N/D-N/D.
Impact Factor: 3.166
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Mancini M, Salomone Megna A, Ragucci M, De Luca M, Marino Marsilia G, Nardone G, Coccoli P, Prinster A, Mannelli L, Vergara E, Monti S, Liuzzi R, Incoronato M
* Reproducibility of shear wave elastography (SWE) in patients with chronic liver disease (88 visite)
Plosone (ISSN: 1932-6203, 1932-6203electronic), 2017 Oct 12; 12(10): e0185391-e0185391.
Impact Factor: 2.766
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Nappi C, Gaudieri V, Acampa W, Assante R, Zampella E, Mainolfi CG, Petretta M, Germano G, Cuocolo A
* Comparison of left ventricular shape by gated SPECT imaging in diabetic and nondiabetic patients with normal myocardial perfusion: A propensity score analysis (112 visite)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2017 Aug 14; 25(2): 394-403.
Impact Factor: 4.011
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Assante R, Acampa W, Zampella E, Arumugam P, Nappi C, Gaudieri V, Panico M, Magliulo M, Tonge CM, Petretta M, Cuocolo A
* Coronary atherosclerotic burden vs. coronary vascular function in diabetic and nondiabetic patients with normal myocardial perfusion: a propensity score analysis (167 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 1619-7070print), 2017 Mar 14; N/D: N/D-N/D.
Impact Factor: 7.704
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Fagoonee S, Famulari ES, Silengo L, Camussi G, Altruda F
* Prospects for Adult Stem Cells in the Treatment of Liver Diseases (110 visite)
Stem Cells Dev (ISSN: 1547-3287), 2016 Sep 7; N/D: N/D-N/D.
Impact Factor: 3.562
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Pisani A, Sabbatini M, Imbriaco M, Riccio E, Rubis N, Prinster A, Perna A, Liuzzi R, Spinelli L, Santangelo M, Remuzzi G, Ruggenenti P
* Long-term Effects of Octreotide on Liver Volume in Patients With Polycystic Kidney and Liver Disease (107 visite)
Clin Gastroenterol H (ISSN: 1542-3565), 2016 Feb 1; N/D: N/D-N/D.
Impact Factor: 7.398
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Petta S, Valenti L, Bugianesi E, Targher G, Bellentani S, Bonino F, Fargion S, Vanni E, Ferrannini E, Loguercio C, Lonardo A, Marra F, Mancini M, Miele L, Nobili V, Baroni GS, Alessandro F, Ballestri S, Brunetto MR, Coco B, Grieco A, Kondili L, Nascimbeni F, Prinster A, Romagnoli D, Taddei S, Vella S
* A "systems medicine" approach to the study of non-alcoholic fatty liver disease (203 visite)
Digest Liver Dis (ISSN: 1590-8658), 2016; 48(3): 333-342.
Impact Factor: 3.061
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Monti SM, Supuran CT, De Simone G
* DPP-4 inhibitors: a patent review (2012 - 2014) (143 visite)
Expert Opin Ther Pat (ISSN: 1354-3776, 1744-7674electronic), 2015 Feb; 25(2): 209-236.
Impact Factor: 4.626
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Tomasello MF, Sinopoli A, Pappalardo G
* On the Environmental Factors Affecting the Structural and Cytotoxic Properties of IAPP Peptides (208 visite)
J Diabetes Res (ISSN: 2314-6745), 2015; articleID918573: 918573-918573.
Impact Factor: 2.431
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Ribaldone DG, Garavagno M, Pellicano R, Bresso F, Fagoonee S, David E, Sapone N, Bonagura AG, Resegotti A, Astegiano M
* Prevalence and prognostic value of hepatic histological alterations in patients with Crohn's disease (146 visite)
Scand J Gastroentero (ISSN: 0036-5521), 2015; 50(12): 1463-1468.
Impact Factor: 2.199
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Coppo C, Bonfanti D, Bo S, Giordanino C, Gallo M, Cococcia S, Ciccone G, Smedile A, Ciancio A, Bugianesi E, Fagoonee S, Pellicano R, Rizzetto M, Saracco GM
* Risk of microangiopathy in type 2 diabetes mellitus patients with or without chronic hepatitis C: Results of a retrospective long-term controlled cohort study (129 visite)
Digest Liver Dis (ISSN: 1590-8658), 2015; 47(5): 405-410.
Impact Factor: 2.719
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Le Moli R, Muscia V, Tumminia A, Frittitta L, Buscema M, Palermo F, Sciacca L, Squatrito S, Vigneri R
* Type 2 diabetic patients with Graves' disease have more frequent and severe Graves' orbitopathy (586 visite)
Nutrition (ISSN: 0939-4753, 1590-3729electronic), 2015; 25(5): 452-457.
Impact Factor: 3.39
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Petretta M, Acampa W, Cuocolo A
* Cardiovascular risk stratification in diabetic patients: is all in METS? (178 visite)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2014 Dec; 21(6): 1144-1147.
Impact Factor: 2.942
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Acampa W, Cantoni V, Green R, Maio F, Daniele S, Nappi C, Gaudieri V, Punzo G, Petretta M, Cuocolo A
* Prognostic value of normal stress myocardial perfusion imaging in diabetic patients: a meta-analysis (140 visite)
J Nucl Cardiol (ISSN: 1071-3581, 1071-3581linking, 1532-6551), 2014 Oct; 21(5): 893-902.
Impact Factor: 2.942
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Salvatore E, Tedeschi E, Mollica C, Vicidomini C, Varrone A, Coda ARD, Brunetti A, Salvatore M, De Michele G, Filla A, Pappata S
* Supratentorial and infratentorial damage in spinocerebellar ataxia 2: a diffusion-weighted MRI study (177 visite)
Mov Disord (ISSN: 0885-3185, 1531-8257), 2014 May; 29(6): 780-786.
Impact Factor: 5.68
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Mancini M, Lanzillo R, Liuzzi R, Di Donato O, Ragucci M, Monti S, Salvatore E, Morra VB, Salvatore M
* Internal jugular vein blood flow in multiple sclerosis patients and matched controls (163 visite) (PDF 137 visite)
Plosone (ISSN: 1932-6203, 1932-6203electronic), 2014 Mar 27; 9(3): e92730-e92730.
Impact Factor: 3.234
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Storto G, Gallicchio R, Maddalena F, Pellegrino T, Petretta M, Fiumara G, Cuocolo A
* Estimation of coronary flow reserve by sestamibi imaging in patients with mild hypertension and normal coronary arteries (128 visite)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1827-1936), 2014 Mar 14; 59(3): 336-341.
Impact Factor: 2.033
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Acampa W, Petretta M, Cuocolo R, Daniele S, Cantoni V, Cuocolo A
* Warranty period of normal stress myocardial perfusion imaging in diabetic patients: A propensity score analysis (172 visite)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2014 Feb; 21(1): 50-56.
Impact Factor: 2.942
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Molino I, Cavaliere C, Salvatore E, Quarantelli M, Colucci L, Fasanaro AM
* Is anterior communicating artery syndrome related to fornix lesions? (121 visite)
J Alzheimers Dis (ISSN: 1387-2877), 2014; 42Suppl3: S199-S199.
Impact Factor: 4.151
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Petretta M, Acampa W, Evangelista L, Daniele S, Zampella E, Assante R, Nappi C, Cantoni V, Fiumara G, Cuocolo A
* Reclassification of cardiovascular risk by myocardial perfusion imaging in diabetic patients with abnormal resting electrocardiogram (159 visite)
Nutrition (ISSN: 0939-4753, 1590-3729electronic), 2014; 24(6): 588-593.
Impact Factor: 3.323
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Milardi D, Sciacca MF, Randazzo L, Raudino A, La Rosa C
* The role of calcium, lipid membranes and islet amyloid polypeptide in the onset of type 2 diabetes: Innocent bystanders or partners in a crime? (206 visite)
Front Endocrinol (ISSN: 1664-2392, 1664-2392linking, 1664-2392print), 2014; 5(DEC): 216-216.
Impact Factor: 3.675
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Bellia F, GrassoG
* The role of copper(II) and zinc(II) in the degradation of human and murine IAPP by insulin-degrading enzyme (171 visite)
J Mass Spectrom (ISSN: 1076-5174, 1096-9888), 2014; 49(4): 274-279.
Impact Factor: 2.379
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Ferro A, Petretta M, Acampa W, Fiumara G, Daniele S, Petretta MP, Cantoni V, Cuocolo A
* Post-stress left ventricular ejection fraction drop in patients with diabetes: A gated myocardial perfusion imaging study (145 visite)
Bmc Cardiovasc Disor (ISSN: 1471-2261), 2013 Nov 14; 13: 99-99.
Impact Factor: 1.5
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Petretta M, Acampa W, Daniele S, Petretta MP, Plaitano M, Cuocolo A
* Transient ischemic dilation in patients with diabetes mellitus: prognostic value and effect on clinical outcome after coronary revascularization (146 visite)
Circ Cardiovasc Imaging (ISSN: 1942-0080, 1941-9651), 2013 Nov; 6(6): 908-915.
Impact Factor: 1.783
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Petretta M, Fiumara G, Petretta MP, Cuocolo A
* Detection of silent myocardial ischemia: is it clinically relevant? (134 visite)
J Nucl Cardiol (ISSN: 1532-6551, 1071-3581, 1532-6551electronic), 2013 Oct; 20(5): 707-710.
Impact Factor: 2.645
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Comi G, Battaglia MA, Bertolotto A, Del Sette M, Ghezzi A, Malferrari G, Salvetti M, Sormani MP, Tesio L, Stolz E, Zaratin P, Mancardi G, Mancini M
* Observational case-control study of the prevalence of chronic cerebrospinal venous insufficiency in multiple sclerosis: results from the CoSMo study (123 visite)
Mult Scler (ISSN: 1477-0970, 1352-4585, 1352-4585linking), 2013 Oct; 19(11): 1508-1517.
Impact Factor: 4.863
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Paolillo S, Rengo G, Pagano G, Pellegrino T, Savarese G, Femminella GD, Tuccillo M, Boemio A, Attena E, Formisano R, Petraglia L, Scopacasa F, Galasso G, Leosco D, Trimarco B, Cuocolo A, Perrone-Filardi P
* Impact of diabetes on cardiac sympathetic innervation in patients with heart failure: a 123I meta-iodobenzylguanidine (123I MIBG) scintigraphic study (152 visite)
Diabetes Care (ISSN: 1935-5548, 0149-5992), 2013 Sep; 36(8): 2395-2401.
Impact Factor: 8.57
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Vitale M, Luongo D, Naviglio D, Bozzetto L, Mirabella M, Rivieccio AM, Giacco A, Rivellese AA
* Trans fatty acids consumption in type 1 diabetic patients: evaluation by dietary records and measurement in serum phospholipids (179 visite)
Acta Diabetol (ISSN: 0940-5429, 1432-5233electronic), 2013 Aug; 50(4): 651-654.
Impact Factor: 3.679
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Mancini M, Masulli M, Liuzzi R, Mainenti PP, Ragucci M, Maurea S, Riccardi G, Vaccaro O
* Renal duplex sonographic evaluation of type 2 diabetic patients (182 visite)
J Ultrasound Med (ISSN: 1550-9613, 0278-4297), 2013 Jun; 32(6): 1033-1040.
Impact Factor: 1.532
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Acampa W, Petretta M, Daniele S, Del Prete G, Assante R, Zampella E, Cuocolo A
* Incremental prognostic value of stress myocardial perfusion imaging in asymptomatic diabetic patients (129 visite)
Atherosclerosis (ISSN: 0021-9150, 1879-1484), 2013 Apr; 227(2): 307-312.
Impact Factor: 3.971
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Paolillo S, Rengo G, Pagano G, Pellegrino T, Savarese G, Femminella GD, Tuccillo M, Boemio A, Attena E, Formisano R, Petraglia L, Scopacasa F, Galasso G, Leosco D, Trimarco B, Cuocolo A, Perrone-Filardi P
* IMPACT OF DIABETES MELLITUS IN IODINE-123 META-IODOBENZYLGUANIDINE (I123MIBG) CARDIAC UPTAKE IN PATIENTS WITH HEART FAILURE (136 visite)
Journal Of The American College Of Cardiology (ISSN: 0735-1097), 2013 Mar 12; 61(10): 2395-2401.
Impact Factor: 15.343
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Pasanisi F, Pace L, Fonti R, Marra M, Sgambati D, De Caprio C, De Filippo E, Vaccaro A, Salvatore M, Contaldo F
* Evidence of brown fat activity in constitutional leanness (167 visite)
J Clin Endocrinol Metab (ISSN: 1945-7197, 0021-972x, 0021-972xlinking), 2013 Mar; 98(3): 1214-1218.
Impact Factor: 6.31
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Lanzillo R, Mancini M, Liuzzi R, Di Donato O, Salvatore E, Maglio V, Vacca G, Amato L, D'Anna G, Brunetti A, Brescia Morra V
* Chronic cerebrospinal venous insufficiency in multiple sclerosis: a highly prevalent age-dependent phenomenon (176 visite)
Bmc Neurol (ISSN: 1471-2377), 2013 Feb 13; 13: 20-20.
Impact Factor: 2.486
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Petretta M, Acampa W, Daniele S, Petretta MP, Nappi C, Assante R, Zampella E, Costanzo P, Perrone-Filardi P, Cuocolo A
* Transient ischemic dilation in SPECT myocardial perfusion imaging for prediction of severe coronary artery disease in diabetic patients (160 visite)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2013 Feb; 20(1): 45-52.
Impact Factor: 2.645
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Petretta M, Acampa W, Fiumara G, Cuocolo A
* Cardiovascular risk stratification in diabetic patients (40 visite)
Clin Transl Imaging (ISSN: 2281-5872, 2281-5872print, 2281-7565online), 2013; 1(5): 325-339.
Impact Factor: 0
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Bellia F, Pietropaolo A, Grasso G
* Formation of insulin fragments by insulin-degrading enzyme: The role of zinc(II) and cystine bridges (139 visite)
J Mass Spectrom (ISSN: 1076-5174, 1096-9888), 2013; 48(2): 135-140.
Impact Factor: 2.709
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Grasso G, Salomone F, Tundo GR, Pappalardo G, Ciaccio C, Spoto G, Pietropaolo A, Coletta M, Rizzarelli E
* Metal ions affect insulin-degrading enzyme activity (139 visite)
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2012 Dec; 117: 351-358.
Impact Factor: 3.197
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Erro R, Pappata S, Amboni M, Vicidomini C, Longo K, Santangelo G, Picillo M, Vitale C, Moccia M, Giordano F, Brunetti A, Pellecchia MT, Salvatore M, Barone P
* Anxiety is associated with striatal dopamine transporter availability in newly diagnosed untreated Parkinson's disease patients (189 visite)
Parkinsonism Relat D (ISSN: 1873-5126, 1353-8020, 1873-5126electronic), 2012 Nov; 18(9): 1034-1038.
Impact Factor: 3.274
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Stanzione F, De Simone A, Esposito L, Vitagliano L
* Dynamical Properties of Steric Zipper Polymorphs Formed by a IAPP-Derived Peptide (204 visite)
Protein Pept Lett (ISSN: 0929-8665, 1875-5305), 2012 Sep; 19(8): 846-851.
Impact Factor: 1.994
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Marciano C, Galderisi M, Gargiulo P, Acampa W, D'Amore C, Esposito R, Capasso E, Savarese G, Casaretti L, Lo Iudice F, Esposito G, Rengo G, Leosco D, Cuocolo A, Perrone-Filardi P
* Effects of type 2 diabetes mellitus on coronary microvascular function and myocardial perfusion in patients without obstructive coronary artery disease (215 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2012 Jul; 39(7): 1199-1206.
Impact Factor: 5.114
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Bozzetto L, Prinster A, Annuzzi G, Costagliola L, Mangione A, Vitelli A, Mazzarella R, Longobardo M, Mancini M, Vigorito C, Riccardi G, Rivellese AA
* Liver fat is reduced by an isoenergetic MUFA diet in a controlled randomized study in type 2 diabetic patients (180 visite)
Diabetes Care (ISSN: 1935-5548, 0149-5992), 2012 Jul; 35(7): 1429-1435.
Impact Factor: 7.735
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Perrone-Filardi P, Musella F, Savarese G, Cecere M, Marciano C, Scala O, Rengo G, Dellegrottaglie S, Cuocolo A, Leosco D
* Coronary computed tomography: current role and future perspectives for cardiovascular risk stratification (208 visite)
Eur Heart J-Card Img (ISSN: 2047-2412, 2047-2404, 2047-2412electronic), 2012 Jun; 13(6): 453-458.
Impact Factor: 3.669
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Franchin A, Corradin ML, Giantin V, Rossi F, Zanatta F, Attanasio F, Toffanello ED, Manzato E
* Diabetes in a geriatric ward: Efficacy and safety of new insulin analogs in very old inpatients (146 visite)
Aging Clin Exp Res (ISSN: 1594-0667, 1720-8319), 2012 Jun; 24(SUPPL.3): 17-19.
Impact Factor: 1.006
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Pier PM
* RE: Imaging Features of Hepato-Splenic Amyloidosis at PET/CT (139 visite)
Korean Journal Of Radiology (ISSN: 1229-6929), 2012 May; 13(3): 368-369.
Impact Factor: 1.555
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Mancini M, Morra VB, Di Donato O, Maglio V, Lanzillo R, Liuzzi R, Salvatore E, Brunetti A, Iaccarino V, Salvatore M
* Multiple sclerosis: cerebral circulation time (135 visite)
Radiology (ISSN: 1527-1315, 0033-8419, 1527-1315electronic), 2012 Mar; 262(3): 947-955.
Impact Factor: 6.339
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Acampa W, Petretta M, Evangelista L, Daniele S, Xhoxhi E, De Rimini ML, Cittanti C, Marranzano F, Spadafora M, Baldari S, Mansi L, Cuocolo A
* Myocardial perfusion imaging and risk classification for coronary heart disease in diabetic patients. The IDIS study: A prospective, multicentre trial (145 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2012 Mar; 39(3): 387-395.
Impact Factor: 5.114
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Lanzillo R, Di Somma C, Quarantelli M, Ventrella G, Gasperi M, Prinster A, Vacca G, Pivonello C, Orefice G, Colao A, Morra VB
* Insulin-like growth factor (IGF)-I and IGF-binding protein-3 serum levels in relapsing-remitting and secondary progressive multiple sclerosis patients (151 visite)
Eur J Neurol (ISSN: 1351-5101, 1468-1331electronic), 2011 Dec; 18(12): 1402-1406.
Impact Factor: 3.692
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Giacco R, Della Pepa G, Luongo D, Riccardi G
* Whole grain intake in relation to body weight: From epidemiological evidence to clinical trials (182 visite)
Nutrition (ISSN: 0939-4753, 1590-3729electronic), 2011 Dec; 21(12): 901-908.
Impact Factor: 3.731
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Pappata S, Santangelo G, Aarsland D, Vicidomini C, Longo K, Bronnick K, Amboni M, Erro R, Vitale C, Caprio MG, Pellecchia MT, Brunetti A, De Michele G, Salvatore M, Barone P
* Mild cognitive impairment in drug-naive patients with PD is associated with cerebral hypometabolism (182 visite)
Neurology (ISSN: 0028-3878, 1526-632x, 1526-632xelectronic), 2011 Oct 4; 77(14): 1357-1362.
Impact Factor: 8.312
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Acampa W, Di Taranto MD, Morgante A, Salvatore B, Evangelista L, Ricci F, Costanzo P, De Sisto E, Filardi PP, Petretta M, Fortunato G, Cuocolo A
* C-reactive protein levels are associated with paraoxonase polymorphism L55M in patients undergoing cardiac SPECT imaging (166 visite)
Scand J Clin Lab Invest (ISSN: 0036-5513, 1502-7686), 2011 May; 71(3): 179-184.
Impact Factor: 1.156
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Scognamiglio PL, Doti N, Grieco P, Pedone C, Ruvo M, Marasco D
* Discovery Of Small Peptide Antagonists Of Ped/Pea15-D4alpha Interaction From Simplified Combinatorial Libraries (221 visite)
Chem Biol Drug Des Chemical Biology And Drug Design (ISSN: 1747-0277, 1747-0285), 2011 May; 77(5): 319-327.
Impact Factor: 2.282
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Striano P, Caranci F, Pappata S, Zara F, Striano S
* Hemidystonia in uncontrolled type 2 diabetes mellitus (90 visite)
Arch Neurol (ISSN: 1538-3687electronic, 0003-9942linking), 2011 May; 68(5): 674-675.
Impact Factor: 7.584
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Dinacci D, Tessitore A, Russo AA, De Bonis ML, Lavorgna L, Picconi O, Sacco R, Bonavita S, Gallo A, Servillo G, Marcuccio L, Comerci M, Galletti P, Alfano B, Tedeschi G
* BDNF Val66Met polymorphism and brain volumes in multiple sclerosis (204 visite) (PDF 154 visite)
Neurol Sci (ISSN: 1590-1874, 1590-3478, 1590-1874linking), 2011 Feb; 32(1): 117-123.
Impact Factor: 1.315
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Milardi D, Sciacca MFM, Pappalardo M, Grasso DM, La Rosa C
* The Role Of Aromatic Side-Chains In Amyloid Growth And Membrane Interaction Of The Islet Amyloid Polypeptide Fragment Lanflvh (178 visite)
Eur Biophys J, 2011 Jan; 40(1): 1-12.
Impact Factor: 3.832
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Bombardieri E, Ambrosini V, Aktolun C, Baum RP, Bishof-delaloye A, Del Vecchio S, Maffioli L, Mortelmans L, Oyen W, Pepe G, Chiti A
* In-111-pentetreotide scintigraphy: procedure guidelines for tumour imaging (187 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2010 Jul; 37(7): 1441-1448.
Impact Factor: 5.036
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Pappata S, Varrone A, Vicidomini C, Milan G, De Falco C, Sansone V, Iavarone A, Comerci M, Loré E, Panico M, Quarantelli M, Postiglione A, Salvatore M
* SPECT imaging of GABAA/benzodiazepine receptors and cerebral perfusion in mild cognitive impairment (225 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2010 Jun; 37(6): 1156-1163.
Impact Factor: 5.036
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Capaccio D, Ciccodicola A, Sabatino L, Casamassimi A, Pancione M, Fucci A, Febbraro, Merlino A, Graziano G, Colantuoni V
* A novel germline mutation in Peroxisome Proliferator-Activated Receptor γ gene associated with large intestine polyp formation and dyslipidemia (130 visite)
Bba-Mol Basis Dis (ISSN: 0925-4439, 0006-3002, 1570-9639), 2010; 1802(6): 572-581.
Impact Factor: 2.773
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Galasso G, De Rosa R, Piscione F, Iaccarino G, Vosa C, Sorriento D, Piccolo R, Rapacciuolo A, Walsh K, Chiariello M
* Myocardial expression of FOXO3a-Atrogin-1 pathway in human heart failure (119 visite)
Eur J Heart Fail European Journal Of Heart Failure (ISSN: 1388-9842), 2010; 12(12): 1290-1296.
Impact Factor: 4.512
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Coppola G, Fortunato D, Auricchio G, Mainolfi C, Operto FF, Signoriello G, Pascotto A, Salvatore M
* Bone mineral density in children, adolescents, and young adults with epilepsy (169 visite)
Epilepsia (ISSN: 1528-1167, 0013-9580), 2009 Sep; 50(9): 2140-2146.
Impact Factor: 4.052
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Cuocolo A, Concilio C, Acampa W, Ferro A, Evangelista L, Daniele S, Petretta M
* Cardiovascular risk stratification of diabetic patients (421 visite)
Minerva Endocrinol (ISSN: 0391-1977, 1827-1634electronic), 2009 Sep; 34(3): 205-221.
Impact Factor: 1.464
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Palladino P, Ronga L, Benedetti E, Rossi F, Ragone R
* Peptide Fragment Approach to Prion Misfolding: The Alpha-2 Domain (149 visite)
Int J Pept Res Ther (ISSN: 1573-3149, 0929-5666), 2009 Sep; 15(3): 165-176.
Impact Factor: 0.869
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Lanzillo R, Di Somma C, Quarantelli M, Gasperi M, Ventrella G, Prinster A, Vacca G, Orefice G, Colao A, Morra VB
* Serum levels of insulin like growth factor-1 and insulin like growth factor binding protein-3 in relapsing and secondary progressive multiple sclerosis (167 visite)
Mult Scler (ISSN: 1352-4585, 1477-0970, 1352-4585linking), 2009 Sep; 15(9): 1402-1406.
Impact Factor: 3.279
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Masulli M, Mancini M, Liuzzi R, Daniele S, Mainenti PP, Vergara E, Genovese S, Salvatore M, Vaccaro O
* Measurement of the intrarenal arterial resistance index for the identification and prediction of diabetic nephropathy (195 visite)
Nutrition (ISSN: 0939-4753, 1590-3729electronic, 0939-4753linking), 2009 Jun; 19(5): 358-364.
Impact Factor: 3.517
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Sandomenico A, Monti SM, Sabatella M, De Capua A, Tornatore L, Doti N, Viparelli F, Dathan NA, Pedone C, Ruvo M, Marasco D
* Protein-protein interactions: a simple strategy to identify binding sites and peptide antagonists (189 visite)
Chem Biol Drug Des Chemical Biology And Drug Design (ISSN: 1747-0285, 1747-0277), 2009 May; 73(5): 483-493.
Impact Factor: 2.473
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Gentile I, Viola C, Graf M, Liuzzi R, Quarto M, Cerini R, Piazza M, Borgia G
* A simple noninvasive score predicts gastroesophageal varices in patients with chronic viral hepatitis (190 visite)
J Clin Gastroenterol (ISSN: 0192-0790), 2009 Jan; 43(1): 81-87.
Impact Factor: 2.207
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De Simone G, Supuran CT
* Drug Design of Antiobesity Carbonic Anhydrase Inhibitors (153 visite)
Drug Des Of Zinc Enzyme Inhibitors (ISSN: 9780-4702, 9780-470275009), 2009; 66(DECEMBERSPEC.I): 241-254.
Impact Factor: 1.156
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Spinelli L, Nicolai E, Acampa W, Imbriaco M, Pisani A, Rao MA, Scopacasa F, Cianciaruso B, De Luca N, Cuocolo A
* Cardiac performance during exercise in patients with Fabry's disease (139 visite)
Eur J Clin Invest (ISSN: 0014-2972, 1365-2362), 2008 Dec; 38(12): 910-917.
Impact Factor: 2.784
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De Bonis S, Rendina D, Vargas G, Minno DD, Piedimonte V, Gallotta G, Postiglione A
* Predictors of In-Hospital and Long-Term Clinical Outcome in Elderly Patients with Massive Pulmonary Embolism Receiving Thrombolytic Therapy (104 visite)
J Am Geriatr Soc (ISSN: 0002-8614), 2008 Dec; 56(12): 2273-2277.
Impact Factor: 3.805
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Milardi D, Pappalardo M, Pannuzzo M, Grasso DM, Rosa CL
* The role of the Cys2-Cys7 disulfide bridge in the early steps of Islet amyloid polypeptide aggregation: A molecular dynamics study (229 visite)
Chem Phys Lett (ISSN: 0009-2614), 2008 Oct 1; 463(4-6): 396-399.
Impact Factor: 2.169
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Sciacca MFM, Pappalardo M, Milardi D, Grasso DM, La Rosa C
* Calcium-Activated Membrane Interaction Of The Islet Amyloid Polypeptide: Implications In The Pathogenesis Of Type Ii Diabetes Mellitus (272 visite)
Arch Biochem Biophys, 2008 Sep 15; 65(1-2): 291-298.
Impact Factor: 3.043
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Viparelli F, Cassese A, Doti N, Paturzo F, Marasco D, Dathan NA, Monti SM, Basile G, Ungaro P, Sabatella M, Miele C, Teperino R, Consiglio E, Pedone C, Beguinot F, Formisano P, Ruvo M
* Targeting of PED/PEA-15 molecular interaction with phospholipase D1 enhances insulin sensitivity in skeletal muscle cells (187 visite)
J Biol Chem (ISSN: 0021-9258, 1083-351x), 2008 Sep 1; 283(31): 21769-21778.
Impact Factor: 5.52
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Varrone A, Sansone V, Pellecchia MT, Amboni M, Salvatore E, De Michele G, Filla A, Barone P, Pappata S, Salvatore M
* Comparison between a dual-head and a brain-dedicated SPECT system in the measurement of the loss of dopamine transporters with [123I]FP-CIT (159 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2008 Jul; 35(7): 1343-1349.
Impact Factor: 4.532
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Acampa W, Petretta M, Evangelista L, Nappi G, Luongo L, Petretta MP, Cuocolo A
* Stress cardiac single-photon emission computed tomographic imaging late after coronary artery bypass surgery for risk stratification and estimation of time to cardiac events (116 visite)
J Thorac Cardiovasc Surg (ISSN: 0022-5223, 1097-685x), 2008 Jul; 136(1): 46-51.
Impact Factor: 3.037
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Petretta M, Soricelli A, Storto G, Cuocolo A
* Assessment of coronary flow reserve using single photon emission computed tomography with technetium 99m-labeled tracers (172 visite)
J Nucl Cardiol (ISSN: 1532-6551, 1071-3581, 1532-6551electronic), 2008 May; 15(3): 456-465.
Impact Factor: 2.442
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Cigliano L, Maresca B, Salvatore A, Nino M, Monfrecola G, Ayala F, Carlucci A, Pugliese RC, Pedone C, Abrescia P
* Haptoglobin from psoriatic patients exhibits decreased activity in binding haemoglobin and inhibiting lecithin-cholesterol acyltransferase activity (145 visite)
Journal Of The European Academy Of Dermatology And Venereology (ISSN: 1468-3083, 0926-9959), 2008 Apr; 22(4): 417-425.
Impact Factor: 2.276
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Goldfine ID, Maddux BA, Youngren JF, Reaven G, Accili D, Trischitta V, Vigneri R, Frittitta L
* The role of membrane glycoprotein plasma cell antigen 1 ectonucleotide pyrophosphatase phosphodiesterase 1 in the pathogenesis of insulin resistance and related abnormalities (214 visite)
Endocrine Reviews (ISSN: 0163-769x), 2008 Feb; 29(1): 62-75.
Impact Factor: 18.562
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Petretta M, Acampa W, Evangelista L, Daniele S, Ferro A, Cuocolo A
* Impact of inducible ischemia by stress SPECT in cardiac risk assessment in diabetic patients: Rationale and design of a prospective, multicenter trial (131 visite)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 2008 Jan; 15(1): 100-104.
Impact Factor: 2.442
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Tauchmanova L, Pivonello R, De Martino MC, Rusciano A, De Leo M, Ruosi C, Mainolfi C, Lombardi G, Salvatore M, Colao A
* Effects of sex steroids on bone in women with subclinical or overt endogenous hypercortisolism (148 visite)
Eur J Endocrinol (ISSN: 0804-4643), 2007 Sep; 157(3): 359-366.
Impact Factor: 3.239
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Sorrentino AR, Acampa W, Petretta M, Mainolfi C, Salvatore M, Cuocolo A
* Comparison of the prognostic value of SPECT after nitrate administration and metabolic imaging by PET in patients with ischaemic left ventricular dysfunction (150 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2007 Apr; 34(4): 558-562.
Impact Factor: 4.101
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Storto G, Pellegrino T, Sorrentino AR, Luongo L, Petretta M, Cuocolo A
* Estimation of coronary flow reserve by sestamibi imaging in type 2 diabetic patients with normal coronary arteries (126 visite)
J Nucl Cardiol (ISSN: 1532-6551, 1071-3581, 1532-6551electronic), 2007 Apr; 14(2): 194-199.
Impact Factor: 2.359
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Evangelista L, Ferro A, Acampa W, Capasso R, De Rimini ML, Cittanti C, Marranzano F, Spadafora M, Baldari S, Mansi L, Petretta M, Cuocolo A
* A prospective, multi-center trial to assess the prevalence and the clinical predictors of myocardial ischemia in patients presenting with diabetes mellitus and suspected or documented coronary artery disease (110 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2006 Sep; 33: N/D-N/D.
Impact Factor: 4.041
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Tauchmanovà L, Pivonello R, Di Somma C, Rossi R, De Martino MC, Camera L, Klain M, Salvatore M, Lombardi G, Colao A
* Bone demineralization and vertebral fractures in endogenous cortisol excess: Role of disease etiology and gonadal status (159 visite)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2006 May; 91(5): 1779-1784.
Impact Factor: 5.799
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Di Bonito P, Rinaldi M, Genovese S, Parillo M, Gruppo di studio regionale FADOI, Lucibelli L, Miano P, Piantadosi S, Sassi G, Caiazzo G, Marrone G, De Feo EM, Piscopo G, Di Domenico A, Visconti M, Nicoletti A, Luca S, Cunzolo D, Cianciullo M, Tortora A, Zinno A, D’Auria S, Rinaldi C, Pascucci D, Gennaro MD, Zerella F, Forte R, Grimaldi U, Foschi A, Boniello B, Garrulo A, Pontieri A, Dello Iacono N, Mancini M, D’avanzo A, Di Guglielmo G, Sossio F
* Known And Unknown Diabetes Mellitus Among Patients Hositalized In Internal Medicine Units Of The Campania Region (southern Italy) (111 visite)
G It Diabetol Metab, 2006; 26: 5-9.
Impact Factor: 0
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Colao A, Di Somma C, Cuocolo A, Spinelli L, Acampa W, Spiezia S, Rota F, Savanelli MC, Lombardi G
* Does a gender-related effect of growth hormone (GH) replacement exist on cardiovascular risk factors, cardiac morphology, and performance and atherosclerosis? Results of a two-year open, prospective study in young adult men and women with severe GH deficiency (141 visite)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2005 Sep; 90(9): 5146-5155.
Impact Factor: 6.02
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Vicario MLE, Cirillo L, Storto G, Pellegrino T, Ragone N, Fontanella L, Petretta M, Bonaduce D, Cuocolo A
* Influence of risk factors on coronary flow reserve in patients with 1-vessel coronary artery disease (128 visite)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2005 Sep; 46(9): 1438-1443.
Impact Factor: 4.684
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Foti D, Chiefari E, Fedele M, Iuliano R, Brunetti L, Paonessa F, Manfioletti G, Barbetti F, Brunetti A, Croce CM, Fusco A, Brunetti A
* Lack of the architectural factor HMGA1 causes insulin resistance and diabetes in humans and mice (133 visite)
Nat Med (ISSN: 1078-8956, 0034-7264), 2005 Jul; 11(7): 765-773.
Impact Factor: 28.878
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Colao A, Di Somma C, Cuocolo A, Filippella M, Rota F, Acampa W, Savastano S, Salvatore M, Lombardi G
* The severity of growth hormone deficiency correlates with the severity of cardiac impairment in 100 adult patients with hypopituitarism: An observational, case-control study (134 visite)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2004 Dec; 89(12): 5998-6004.
Impact Factor: 5.778
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Giacco R, Clemente G, Luongo D, Lasorella G, Fiume I, Brouns F, Bornet F, Patti L, Cipriano P, Rivellese AA, Riccardi G
* Effects of short-chain fructo-oligosaccharides on glucose and lipid metabolism in mild hypercholesterolaemic individuals (164 visite)
Clin Nutr (ISSN: 0261-5614), 2004 Jun; 23(3): 331-340.
Impact Factor: 2.019
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Varrone A, Salvatore E, De Michele G, Barone P, Sansone V, Pellecchia MT, Castaldo I, Coppola G, Brunetti A, Salvatore M, Pappata S, Filla A
* Reduced Striatal [123I]FP-CIT Binding in SCA2 Patients without Parkinsonism (135 visite)
Annals Of Neurology, 2004 Mar; 55(3): 426-430.
Impact Factor: 11.91
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Clemente G, Mancini M, Nazzaro F, Lasorella G, Rivieccio A, Palumbo AM, Rivellese AA, Ferrara L, Giacco R
* Effects of different dairy products on postprandial lipemia (133 visite)
Nutrition (ISSN: 0939-4753, 1590-3729electronic), 2003 Dec; 13(6): 377-383.
Impact Factor: 2.148
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Mainenti PP, D'Agostino L, Soscia E, Romano M, Salvatore M
* Hepatic and splenic amyloidosis: Dual-phase spiral CT findings (145 visite)
Abdom Imaging (ISSN: 0942-8925, 1432-0509), 2003 Sep; 28(5): 688-690.
Impact Factor: 0.996
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Tauchmanova L, De Rosa G, Serio B, Fazioli F, Mainolfi C, Lombardi G, Colao A, Salvatore M, Rotoli B, Selleri C
* Avascular necrosis in long-term survivors after allogeneic or autologous stem cell transplantation: A single center experience and a review (159 visite)
Cancer (ISSN: 0008-543x), 2003 May 15; 97(10): 2453-2461.
Impact Factor: 2.045
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Di Somma C, Pivonello R, Loche S, Faggiano A, Klain M, Salvatore M, Lombardi G, Colao A
* Effect of 2 years of cortisol normalization on the impaired bone mass and turnover in adolescent and adult patients with Cushing's disease: A prospective study (179 visite)
Clin Endocrinol (ISSN: 0300-0664, 1365-2265, 1365-2265electronic), 2003 Mar; 58(3): 302-308.
Impact Factor: 2.767
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Le Provost JB, Bartres-faz D, Paillere-martinot ML, Artiges E, Pappata S, Recasens C, Perez-gomez M, Bernardo M, Baeza I, Bayle F, Martinot JL
* Paracingulate sulcus morphology in men with early-onset schizophrenia (127 visite)
Br J Psychiatry (ISSN: 0007-1250), 2003 Mar; 182(MAR.): 228-232.
Impact Factor: 4.421
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Colao A, Marzullo P, Cuocolo A, Spinelli L, Pivonello R, Bonaduce D, Salvatore M, Lombardi G
* Reversal of acromegalic cardiomyopathy in young but not in middle-aged patients after 12 months of treatment with the depot long-acting somatostatin analogue octreotide (162 visite)
Clin Endocrinol (ISSN: 0300-0664, 1365-2265, 1365-2265electronic), 2003 Feb; 58(2): 169-176.
Impact Factor: 2.767
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Petretta M, Vicario ML, Spinelli L, Ferro A, Cuocolo A, Condorelli M, Bonaduce D
* Combined effect of the force-frequency and length-tension mechanisms on left ventricular function in patients with dilated cardiomyopathy (128 visite)
Eur J Heart Fail European Journal Of Heart Failure (ISSN: 1388-9842), 2002 Dec; 4(6): 727-735.
Impact Factor: 2.134
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Ciampi Q, Betocchi S, Lombardi R, Manganelli F, Storto G, Losi MA, Pezzella E, Finizio F, Cuocolo A, Chiariello M
* Hemodynamic determinants of exercise-induced abnormal blood pressure response in hypertrophic cardiomyopathy (109 visite)
Journal Of The American College Of Cardiology (ISSN: 0735-1097), 2002 Jul 17; 40(2): 278-284.
Impact Factor: 6.278
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Manganelli F, Betocchi S, Ciampi Q, Storto G, Losi MA, Violante A, Briguori C, Tocchetti CG, Lombardi R, Cuocolo A, Chiariello M
* Myopia and IOP (161 visite)
Ann Ottalmol Clin Ocul, 2002 Jun 15; 115(10): 1053-1058.
Impact Factor: 0
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Colao A, Cuocolo A, Di Somma C, Cerbone G, Della Morte A, Pivonello R, Nicolai E, Salvatore M, Lombardi G
Does the age of onset of growth hormone deficiency affect cardiac performance? A radionuclide angiography study (120 visite)
Clin Endocrinol (ISSN: 0300-0664, 1365-2265, 1365-2265electronic), 2000 Apr; 52(4): 447-455.
Impact Factor: 2.922
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Tedeschi E, Marano I, Savarese F, Olibet G, Di Salvo E, Brunetti A, Sodano A
Neurological deficit following spinal anaesthesia: MRI and CT evidence of spinal cord gas embolism (135 visite)
Neuroradiology (ISSN: 0028-3940, 1432-1920electronic, 0028-3940linking), 1999 Apr; 41(4): 275-278.
Impact Factor: 1.287
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Pace L, Perrone-Filardi P, Mainenti PP, Cuocolo A, Vezzuto P, Prastaro M, Varrone A, De Luca G, Soricelli A, Betocchi S, Chiariello M, Salvatore M
Identification of viable myocardium in patients with chronic coronary artery disease using rest-redistribution thallium-201 tomography: Optimal image analysis (127 visite)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1998 Nov; 39(11): 1869-1874.
Impact Factor: 3.064
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De Michele G, Mainenti PP, Soricelli A, Di Salle F, Salvatore E, Longobardi MR, Postiglione A, Salvatore M, Filla A
Cerebral blood flow in spinocerebellar degenerations: a single photon emission tomography study in 28 patients (119 visite)
J Neurol (ISSN: 0340-5354, 1432-1459, 1432-1459electronic), 1998 Sep; 245(9): 603-608.
Impact Factor: 2.3
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Petretta M, Cuocolo A, Nicolai E, Acampa W, Salvatore M, Bonaduce D
Combined assessment of left ventricular function and rest-redistribution regional myocardial thallium-201 activity for prognostic evaluation of patients with chronic coronary artery disease and left ventricular dysfunction (145 visite)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 1998 Jul; 5(4): 378-386.
Impact Factor: 1.336
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Fonti R, Latella G, Caprilli R, Frieri G, Marcheggiano A, Sambuy Y
Carbonic anhydrase I reduction in colonic mucosa of patients with active ulcerative colitis (107 visite)
Digestive Diseases And Sciences (ISSN: 0163-2116), 1998; 43(9): 2086-2092.
Impact Factor: 1.972
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Giacco R, Mancini M, Clemente G, Coppola S, Lasorella G, D’Avanzo G, Rivieccio A M, Ruffa G, Brighenti F, Rivellese AA, Riccardi G
Metabolic effects of resistant starch in patients with Type 2 diabetes (233 visite)
Diabetes Nutr Metab Clin Exp (ISSN: 0394-3402), 1998; 11(6): 330-335.
Impact Factor: 0.629
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Cuocolo A, Nicolai E, Petretta M, Morisco C, DeLuca N, Salvatore M, Trimarco B
One-year effect of myocardial revascularization on resting left ventricular function and regional thallium uptake in chronic CAD (109 visite)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1997 Nov; 38(11): 1684-1692.
Impact Factor: 3.491
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Nappi A, Cuocolo A, Imbriaco M, Nicolai E, Varrone A, Morisco C, Romano M, Trimarco B, Salvatore M
Ambulatory monitoring of left ventricular function: Walk and bicycle exercise in congestive heart failure (111 visite)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1997 Jun; 38(6): 948-953.
Impact Factor: 3.491
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Soricelli A, Postiglione A, GrivetFojaja M, Mainenti PP, Discepolo A, Varrone A, Salvatore M, Lassen N
Reduced cortical distribution volume of iodine-123 iomazenil in Alzheimer's disease as a measure of loss of synapses (131 visite)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1996 Oct; 23(10): 1323-1328.
Impact Factor: 2.692
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Ferrara LA, Iannuzzi R, Gaeta I, Mancini M, Guida L, Marotta T
Left ventricular hypertrophy and hypertension (142 visite)
Clin Exp Hypertens Informa Healthcare, 1996 Jul; 15(6): 1025-1032.
Impact Factor: 0
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Nicolai E, Cuocolo A, Pace L, Maurea S, Nappi A, Imbriaco M, Morisco C, Argenziano L, Salvatore M
Assessment of systolic wall thickening using technetium-99m methoxyisobutylisonitrile in patients with coronary artery disease: relation to thallium-201 scintigraphy with re-injection (151 visite)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1995 Sep; 22(9): 1017-1022.
Impact Factor: 2.692
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Ferrara LA, Mancini M, Iannuzzi R, Marotta T, Gaeta I, Pasanisi F, Postiglione A, Guida L
CAROTID DIAMETER AND BLOOD-FLOW VELOCITIES IN CEREBRAL-CIRCULATION IN HYPERTENSIVE PATIENTS (124 visite)
Stroke (ISSN: 0039-2499), 1995 Mar; 26(3): 418-421.
Impact Factor: 4.323
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Ferrara LA, Mancini M, Celentano A, Galderisi M, Iannuzzi R, Marotta T, Gaeta I
Early changes of the arterial carotid wall in uncomplicated primary hypertensive patients: Study by ultrasound high-resolution B-mode imaging (118 visite)
Arterioscler Thromb Vasc Biol Arteriosclerosis Thrombosis And Vascular Biology (ISSN: 1079-5642, 1049-8834), 1994 Sep; 14(8): 1290-1296.
Impact Factor: 5.317
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Manna R, Salvatore M, Di Leo MA, Scuderi F, Greco AV, Ghirlanda G, Gambassi G
Relationship between urinary neopterin excretion and islet cell antibodies in type 1 (insulin-dependent) diabetes (115 visite)
Diabetes Res (ISSN: 0265-5985), 1991 May; 17(1): 33-36.
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Benzi L, Trischitta V, Ciccarone A, Cecchetti P, Brunetti A, Squatrito S, Marchetti P, Vigneri R, Navalesi R
Improvement with metformin in insulin internalization and processing in monocytes from NIDDM patients (100 visite)
Diabetesdiabetes (ISSN: 0012-1797), 1990 Jul; 39(7): 844-849.
Impact Factor: 8.675
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Trischitta V, Brunetti A, Chiavetta A, Benzi L, Papa V, Vigneri R
Defects in insulin-receptor internalization and processing in monocytes of obese subjects and obese NIDDM patients (108 visite)
Diabetesdiabetes (ISSN: 0012-1797), 1989 Dec; 38(12): 1579-1584.
Impact Factor: 8.675
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Manna R, Salvatore M, Scuderi F, Papa G, Marietti G, Greco AV, Ghirlanda G, Gambassi G
Negative correlation between ICA persistence and beta cell restoration after IDDM diagnosis (100 visite)
Diabetes Res (ISSN: 0265-5985), 1988 Nov; 9(3): 101-103.
Impact Factor: 0
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Serum vitamin A deficiency and increased intrahepatic expression of cytokeratin antigen in alcoholic liver disease (33 visite)
Hepatology (ISSN: 1827-1669electronic, 0026-4806linking), 1988 Sep; 83120693611123109(5): 1019-1026.
Impact Factor: 0.913
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Trischitta V, Benzi L, Brunetti A, Cecchetti P, Marchetti P, Vigneri R, Navalesi R
Intracellular insulin processing is altered in monocytes from patients with type II diabetes mellitus (111 visite)
J Clin Endocrinol Metab (ISSN: 0021-972x), 1987 May; 64(5): 914-920.
Impact Factor: 4.575
Dettagli Esporta in BibTeX Esporta in EndNote
128 Records (122 escludendo Abstract e Conferenze).
Impact factor totale: 485.169 (467.05 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 501.803 (485.902 escludendo Abstract e Conferenze).
Impact factor totale: 485.169 (467.05 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 501.803 (485.902 escludendo Abstract e Conferenze).
Esporta in BibTeX Esporta in EndNote
Ultima modifica di Marco Comerci in data Friday 16 March 2018, 13:45:58
156 visite. Ultima visita in data Friday 08 November 2019, 3:03:43
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