Multivariate normal tissue complication probability modeling of gastrointestinal toxicity after external beam radiotherapy for localized prostate cancer
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Multivariate normal tissue complication probability modeling of gastrointestinal toxicity after external beam radiotherapy for localized prostate cancer (153 visite)

Cella L, D'Avino V, Liuzzi R, Conson M, Doria F, Faiella A, Loffredo F, Salvatore M, Pacelli R

Radiation Oncology (ISSN: 1748-717x), 2013 Sep 23; 8(1): 221-221.



Tipo di articolo: Journal Article,

Impact factor: 2.36, Impact factor a 5 anni: 2.59

Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84884381700&partnerID=40&md5=d12fd25b82e611356f030dd7e4545329

Parole chiave: Anticoagulant Agent, Antihypertensive Agent, Acute Toxicity, Adult, Article, Cancer Hormone Therapy, Cancer Radiotherapy, Cancer Size, External Beam Radiotherapy, Follow Up, Gastrointestinal Toxicity, Gleason Score, Human, Major Clinical Study, Probability, Prostate Cancer, Radiation Dose, Risk Assessment, Scoring System, Area Under The Curve, Computer Assisted Radiotherapy, Gastrointestinal Tract, Middle Aged, Multivariate Analysis, Procedures, Prostatic Neoplasms, Radiation Injuries, Radiation Response, Radiometry, Receiver Operating Characteristic, Very Elderly, 80 And Over, Area Under Curve, Radiotherapy Dosage, Radiotherapy Planning, Computer-Assisted, Roc Curve,

Affiliazioni:

*** IBB - CNR ***
Institute of Biostructures and Bioimaging, National Council of Research (CNR), Naples, Italy
Department of Advanced Biomedical Sciences, Federico II University School of Medicine, Naples, Italy
Department of Physics, University Federico II, Naples, Italy


Riferimenti:

Michalski, J.M., Gay, H., Jackson, A., Radiation dose-volume effects in radiation-induced rectal injury (2010) Int J Radiat Oncol Biol Phys, 76 (3 SUPPL.), pp. S123-S129. , 3319467, 2017150

Cella, L., Lomax, A., Miralbell, R., New techniques in hadrontherapy: intensity modulated proton beams (2001) Phys Med, 17 (SUPPL. 1), pp. 100-102

Skala, M., Rosewall, T., Dawson, L., Patient-assessed late toxicity rates and principal component analysis after image-guided radiation therapy for prostate cancer (2007) Int J Radiat Oncol Biol Phys, 68 (3), pp. 690-698. , 10.1016/j.ijrobp.2006.12.064, 17379434

Efstathiou, J.A., Gray, P.J., Zietman, A.L., Proton beam therapy and localised prostate cancer: current status and controversies (2013) Br J Cancer, 108 (6), pp. 1225-1230. , 10.1038/bjc.2013.100, 23481182

Gulliford, S.L., Partridge, M., Sydes, M.R., Parameters for the Lyman Kutcher Burman (LKB) model of Normal Tissue Complication Probability (NTCP) for specific rectal complications observed in clinical practise (2012) Radiother Oncol, 102 (3), pp. 347-351. , 10.1016/j.radonc.2011.10.022, 22119373

Defraene, G., Van den Bergh, L., Al-Mamgani, A., The benefits of including clinical factors in rectal normal tissue complication probability modeling after radiotherapy for prostate cancer (2012) Int J Radiat Oncol Biol Phys, 82 (3), pp. 1233-1242. , 10.1016/j.ijrobp.2011.03.056, 21664059

Fellin, G., Fiorino, C., Rancati, T., Clinical and dosimetric predictors of late rectal toxicity after conformal radiation for localized prostate cancer: results of a large multicenter observational study (2009) Radiother Oncol, 93 (2), pp. 197-202. , 10.1016/j.radonc.2009.09.004, 19828205

Valdagni, R., Kattan, M.W., Rancati, T., Is it time to tailor the prediction of radio-induced toxicity in prostate cancer patients? Building the first set of nomograms for late rectal syndrome (2012) Int J Radiat Oncol Biol Phys, 82 (5), pp. 1957-1966. , 10.1016/j.ijrobp.2011.03.028, 21640511

Valdagni, R., Vavassori, V., Rancati, T., Increasing the risk of late rectal bleeding after high-dose radiotherapy for prostate cancer: the case of previous abdominal surgery. Results from a prospective trial (2012) Radiother Oncol, 103 (2), pp. 252-255. , 10.1016/j.radonc.2012.03.012, 22521747

Cella, L., Conson, M., Caterino, M., Thyroid V30 predicts radiation-induced hypothyroidism in patients treated with sequential chemo-radiotherapy for Hodgkin's lymphoma (2012) Int J Radiat Oncol Biol Phys, 82 (5), pp. 1802-1808. , 10.1016/j.ijrobp.2010.09.054, 21514076

Cella, L., Liuzzi, R., Conson, M., Multivariate normal tissue complication probability modeling of heart valve dysfunction in hodgkin lymphoma survivors (2013) Int J Radiat Oncol Biol Phys, 87 (2), pp. 304-310. , 10.1016/j.ijrobp.2013.05.049, 23886419

El Naqa, I., Bradley, J., Blanco, A.I., Multivariable modeling of radiotherapy outcomes, including dose-volume and clinical factors (2006) Int J Radiat Oncol Biol Phys, 64 (4), pp. 1275-1286. , 10.1016/j.ijrobp.2005.11.022, 16504765

El Naqa, I., Suneja, G., Lindsay, P.E., Dose response explorer: an integrated open-source tool for exploring and modelling radiotherapy dose-volume outcome relationships (2006) Phys Med Biol, 51 (22), pp. 5719-5735. , 10.1088/0031-9155/51/22/001, 17068361

Gay, H.A., Barthold, H.J., O'Meara, E., Pelvic normal tissue contouring guidelines for radiation therapy: a radiation therapy oncology group consensus panel atlas (2012) Int J Radiat Oncol Biol Phys, 83 (3), pp. e353-e362. , 10.1016/j.ijrobp.2012.01.023, 22483697

Cox, J.D., Stetz, J., Pajak, T.F., Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC) (1995) Int J Radiat Oncol Biol Phys, 31 (5), pp. 1341-1346. , 10.1016/0360-3016(95)00060-C, 7713792

Pacelli, R., Conson, M., Cella, L., Radiation therapy following surgery for localized breast cancer: outcome prediction by classical prognostic factors and approximatedgenetic subtypes (2013) J Radiat Res, 54 (2), pp. 292-298. , 10.1093/jrr/rrs087, 3589925, 23019151

Pedicini, P., Caivano, R., Strigari, L., In regard to Miralbell et al. Re: Dose-fractionation sensitivity of prostate cancer deduced from radiotherapy outcomes of 5969 patients in seven international institutional datasets: alpha/beta = 1.4 (0.9-2.2) Gy (2013) Int J Radiat Oncol Biol Phys, 85 (1), pp. 10-11. , 10.1016/j.ijrobp.2012.03.056, 23237001

Pedicini, P., Strigari, L., Benassi, M., Estimation of a self-consistent set of radiobiological parameters from hypofractionated versus standard radiation therapy of prostate cancer (2013) Int J Radiat Oncol Biol Phys, 85 (5), pp. e231-7. , 10.1016/j.ijrobp.2012.11.033, 23332226

Hamstra, D.A., Stenmark, M.H., Ritter, T., Age and comorbid illness are associated with late rectal toxicity following dose-escalated radiation therapy for prostate cancer (2013) Int J Radiat Oncol Biol Phys, 85 (5), pp. 1246-1253. , 10.1016/j.ijrobp.2012.10.042, 23265567

Trott, K.R., Doerr, W., Facoetti, A., Biological mechanisms of normal tissue damage: importance for the design of NTCP models (2012) Radiother Oncol, 105 (1), pp. 79-85. , 10.1016/j.radonc.2012.05.008, 22748390

van der Schaaf, A., Xu, C.J., van Luijk, P., Multivariate modeling of complications with data driven variable selection: guarding against overfitting and effects of data set size (2012) Radiother Oncol, 105 (1), pp. 115-121. , 10.1016/j.radonc.2011.12.006, 22264894

Heemsbergen, W.D., Peeters, S.T., Koper, P.C., Acute and late gastrointestinal toxicity after radiotherapy in prostate cancer patients: consequential late damage (2006) Int J Radiat Oncol Biol Phys, 66 (1), pp. 3-10. , 10.1016/j.ijrobp.2006.03.055, 16814954

Kharofa, J., Cohen, E.P., Tomic, R., Decreased risk of radiation pneumonitis with incidental concurrent use of angiotensin-converting enzyme inhibitors and thoracic radiation therapy (2012) Int J Radiat Oncol Biol Phys, 84 (1), pp. 238-243. , 10.1016/j.ijrobp.2011.11.013, 22300564

Lee, T.C., Greene-Schloesser, D., Payne, V., Chronic administration of the angiotensin-converting enzyme inhibitor, ramipril, prevents fractionated whole-brain irradiation-induced perirhinal cortex-dependent cognitive impairment (2012) Radiat Res, 178 (1), pp. 46-56. , 10.1667/RR2731.1, 3422865, 22687052

Rehman, A., Schiffrin, E.L., Vascular effects of antihypertensive drug therapy (2010) Curr Hypertens Rep, 12 (4), pp. 226-232. , 10.1007/s11906-010-0117-3, 20514556

Dorr, W., Hendry, J.H., Consequential late effects in normal tissues (2001) Radiother Oncol, 61 (3), pp. 223-231. , 10.1016/S0167-8140(01)00429-7, 11730991

Buettner, F., Gulliford, S.L., Webb, S., Using Bayesian logistic regression to evaluate a new type of dosimetric constraint for prostate radiotherapy treatment planning (2010) Med Phys, 37 (4), pp. 1768-1777. , 10.1118/1.3367013, 20443499

Valdagni, R., Rancati, T., Reducing rectal injury during external beam radiotherapy for prostate cancer (2013) Nat Rev Urol, 10 (6), pp. 345-357. , 10.1038/nrurol.2013.96, 23670182

Loeffler, J.S., Durante, M., Charged particle therapy-optimization, challenges and future directions (2013) Nat Rev Clin Oncol, 10 (7), pp. 411-424. , 10.1038/nrclinonc.2013.79, 23689752

Michalski, J. M., Gay, H., Jackson, A., Radiation dose-volume effects in radiation-induced rectal injury (2010) Int J Radiat Oncol Biol Phys, 76 (3 SUPPL.), pp. S123-S129. , 3319467, 2017150

Efstathiou, J. A., Gray, P. J., Zietman, A. L., Proton beam therapy and localised prostate cancer: current status and controversies (2013) Br J Cancer, 108 (6), pp. 1225-1230. , 10. 1038/bjc. 2013. 100, 23481182

Gulliford, S. L., Partridge, M., Sydes, M. R., Parameters for the Lyman Kutcher Burman (LKB) model of Normal Tissue Complication Probability (NTCP) for specific rectal complications observed in clinical practise (2012) Radiother Oncol, 102 (3), pp. 347-351. , 10. 1016/j. radonc. 2011. 10. 022, 22119373

Gay, H. A., Barthold, H. J., O'Meara, E., Pelvic normal tissue contouring guidelines for radiation therapy: a radiation therapy oncology group consensus panel atlas (2012) Int J Radiat Oncol Biol Phys, 83 (3), pp. e353-e362. , 10. 1016/j. ijrobp. 2012. 01. 023, 22483697

Cox, J. D., Stetz, J., Pajak, T. F., Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC) (1995) Int J Radiat Oncol Biol Phys, 31 (5), pp. 1341-1346. , 10. 1016/0360-3016 (95) 00060-C, 7713792

Hamstra, D. A., Stenmark, M. H., Ritter, T., Age and comorbid illness are associated with late rectal toxicity following dose-escalated radiation therapy for prostate cancer (2013) Int J Radiat Oncol Biol Phys, 85 (5), pp. 1246-1253. , 10. 1016/j. ijrobp. 2012. 10. 042, 23265567

Trott, K. R., Doerr, W., Facoetti, A., Biological mechanisms of normal tissue damage: importance for the design of NTCP models (2012) Radiother Oncol, 105 (1), pp. 79-85. , 10. 1016/j. radonc. 2012. 05. 008, 22748390

Heemsbergen, W. D., Peeters, S. T., Koper, P. C., Acute and late gastrointestinal toxicity after radiotherapy in prostate cancer patients: consequential late damage (2006) Int J Radiat Oncol Biol Phys, 66 (1), pp. 3-10. , 10. 1016/j. ijrobp. 2006. 03. 055, 16814954

Lee, T. C., Greene-Schloesser, D., Payne, V., Chronic administration of the angiotensin-converting enzyme inhibitor, ramipril, prevents fractionated whole-brain irradiation-induced perirhinal cortex-dependent cognitive impairment (2012) Radiat Res, 178 (1), pp. 46-56. , 10. 1667/RR2731. 1, 3422865, 22687052

Loeffler, J. S., Durante, M., Charged particle therapy-optimization, challenges and future directions (2013) Nat Rev Clin Oncol, 10 (7), pp. 411-424. , 10. 1038/nrclinonc. 2013. 79, 23689752



Background: The risk of radio-induced gastrointestinal (GI) complications is affected by several factors other than the dose to the rectum such as patient characteristics, hormonal or antihypertensive therapy, and acute rectal toxicity. Purpose of this work is to study clinical and dosimetric parameters impacting on late GI toxicity after prostate external beam radiotherapy (RT) and to establish multivariate normal tissue complication probability (NTCP) model for radiation-induced GI complications.Methods: A total of 57 men who had undergone definitive RT for prostate cancer were evaluated for GI events classified using the RTOG/EORTC scoring system. Their median age was 73 years (range 53-85). The patients were assessed for GI toxicity before, during, and periodically after RT completion. Several clinical variables along with rectum dose-volume parameters (Vx) were collected and their correlation to GI toxicity was analyzed by Spearman's rank correlation coefficient (Rs). Multivariate logistic regression method using resampling techniques was applied to select model order and parameters for NTCP modeling. Model performance was evaluated through the area under the receiver operating characteristic curve (AUC).Results: At a median follow-up of 30 months, 37% (21/57) patients developed G1-2 acute GI events while 33% (19/57) were diagnosed with G1-2 late GI events. An NTCP model for late mild/moderate GI toxicity based on three variables including V65 (OR = 1.03), antihypertensive and/or anticoagulant (AH/AC) drugs (OR = 0.24), and acute GI toxicity (OR = 4.3) was selected as the most predictive model (Rs = 0.47, p < 0.001; AUC = 0.79). This three-variable model outperforms the logistic model based on V65 only (Rs = 0.28, p < 0.001; AUC = 0.69).Conclusions: We propose a logistic NTCP model for late GI toxicity considering not only rectal irradiation dose but also clinical patient-specific factors. Accordingly, the risk of G1-2 late GI increases as V65 increases, it is higher for patients experiencing previous acute toxicity and it is lower for patients who take AH/AC drugs. The developed NTCP model could represent a potentially useful tool to be used in prospective trial and for comparison among different RT techniques. © 2013 Cella et al.; licensee BioMed Central Ltd.
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Storto G, De Renzo A, Pellegrino T, Perna F, De Falco T, Erra P, Nardelli A, Speranza A, Klain M, Rotoli B, Pace L
* Assessment of Metabolic Response to Radioimmunotherapy with (90)Y-Ibritumomab Tiuxetan in Patients with Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma (118 visite)
Radiology (ISSN: 0033-8419, 1527-1315, 0033-8419linking), 2010 Jan; 254(1): 245-252.
Impact Factor: 6.069
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De Cicco L, Cella L, Liuzzi R, Solla R, Farella A, Punzo G, Tranfa F, Strianese D, Conson M, Bonavolontà G, Salvatore M, Pacelli R
* Radiation therapy in primary orbital lymphoma: A single institution retrospective analysis (189 visite)
Radiat Oncol Radiation Oncology (ISSN: 1748-717x), 2009 Dec 7; 4(1): 60-60.
Impact Factor: 2.36
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Peca C, Pacelli R, Elefante A, Del Basso De Caro ML, Vergara P, Mariniello G, Giamundo A, Maiuri F
* Early clinical and neuroradiological worsening after radiotherapy and concomitant temozolomide in patients with glioblastoma: Tumour progression or radionecrosis? (129 visite)
Clin Neurol Neurosurg (ISSN: 0303-8467), 2009 May; 111(4): 331-334.
Impact Factor: 1.303
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Storto G, Nicolai E, Salvatore M
* [18F]FDG-PET-CT for early monitoring of tumor response: When and why (152 visite)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2009 Apr; 53(2): 167-180.
Impact Factor: 1.724
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Pedone C, Di Pasquale G, Greco C, Gonzini L, Maggioni AP, Pavesi PC, Sabini A, Boccanelli A; In-Acs Outcome Investigators
* Prescription at discharge of recommended treatments for secondary prevention in patients with ST-segment elevation myocardial infarction according to reperfusion strategies. Results from the IN-ACS outcome study (125 visite)
Acute Cardiac Care (ISSN: 1748-295x, 1748-2941), 2009; 11(4): 222-228.
Impact Factor: 0
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De Bonis S, Rendina D, Vargas G, Minno DD, Piedimonte V, Gallotta G, Postiglione A
* Predictors of In-Hospital and Long-Term Clinical Outcome in Elderly Patients with Massive Pulmonary Embolism Receiving Thrombolytic Therapy (92 visite)
J Am Geriatr Soc (ISSN: 0002-8614), 2008 Dec; 56(12): 2273-2277.
Impact Factor: 3.805
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Hesse B, Lindhardt TB, Acampa W, Anagnostopoulos C, Ballinger J, Bax JJ, Edenbrandt L, Flotats A, Germano G, Stopar TG, Franken P, Kelion A, Kjaer A, Le Guludec D, Ljungberg M, Maenhout AF, Marcassa C, Marving J, Mckiddie F, Schaefer WM, Stegger L, Underw
* EANM/ESC guidelines for radionuclide imaging of cardiac function (236 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2008 Apr; 35(4): 851-885.
Impact Factor: 4.532
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Picardi M, De Renzo A, Pane F, Nicolai E, Pacelli R, Salvatore M, Rotoli B
* Randomized comparison of consolidation radiation versus observation in bulky Hodgkin's lymphoma with post-chemotherapy negative positron emission tomography scans (143 visite)
Leuk Lymphoma (ISSN: 1042-8194, 1026-8022linking), 2007 Sep; 48(9): 1721-1727.
Impact Factor: 1.512
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Catalano L, Del Vecchio S, Petruzziello F, Fonti R, Salvatore B, Martorelli C, Califano C, Caparrotti G, Segreto S, Pace L, Rotoli B
* Sestamibi and FDG-PET scans to support diagnosis of jaw osteonecrosis (147 visite)
Ann Hematol (ISSN: 0939-5555, 0939-5555linking), 2007 Jun; 86(6): 415-423.
Impact Factor: 2.342
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Iaccarino G, Izzo R, Trimarco V, Cipolletta E, Lanni F, Sorriento D, Iovino GL, Rozza F, De Luca N, Priante O, Di Renzo G, Trimarco B
* β 2-Adrenergic receptor polymorphisms and treatment-induced regression of left ventricular hypertrophy in hypertension (115 visite)
Clin Pharmacol Ther Clinical Pharmacology And Therapeutics (ISSN: 0009-9236), 2006; 80(6): 633-645.
Impact Factor: 8.066
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Porcellini M, Mainenti PP, Bracale U
* Endograft repair of spontaneous infrarenal abdominal aortic dissection (68 visite)
Journal Of Vascular Surgery (ISSN: 0741-5214), 2005 Jan; 41(1): 155-155.
Impact Factor: 3.173
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Portella G, Pacelli R, Libertini S, Cella L, Vecchio G, Salvatore M, Fusco A
* ONYX-015 Enhances Radiation-Induced Death of Human Anaplastic Thyroid Carcinoma Cells (155 visite)
J Clin Endocrinol Metab Journal Of Clinical Endocrinology And Metabolism (ISSN: 0021-972x), 2003 Oct 1; 88(10): 5027-5032.
Impact Factor: 5.873
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Del Vecchio S, Zannetti A, Aloj L, Caracò C, Ciarmiello A, Salvatore M
* Inhibition of early Tc-99m-MIBI uptake by Bcl-2 anti-apoptotic protein overexpression in untreated breast carcinoma (172 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2003 Jun; 30(6): 879-887.
Impact Factor: 3.324
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Lomax AJ, Cella L, Weber D, Kurtz JM, Miralbell R
* Potential role of IMRT and protons in the treatment of the breast and regional nodes (127 visite)
Int J Rad Oncol Biol Phys, 2003 Mar 1; 48(3Supplement): 785-792.
Impact Factor: 0.155
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Del Vecchio S, Zannetti A, Aloj L, Salvatore M
* MIBI as prognostic factor in breast cancer (137 visite)
Q J Nucl Med (ISSN: 1124-3937, 1125-0135), 2003 Mar; 47(1): 46-50.
Impact Factor: 2.222
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Lomax AJ, Cella L, Weber D, Kurtz JM, Miralbell R
* Potential role of intensity-modulated photons and protons in the treatment of the breast and regional nodes (92 visite)
Int J Radiat Oncol (ISSN: 0360-3016, 1879-355x, 1879-355xelectronic), 2003; 55(3): 785-792.
Impact Factor: 4.285
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Cama G, Vassallo P, Alberti D, Cante D, Solla R, Punzo G, Cella L, Pacelli R
* Primary non-Hodgkin's lymphoma of the lacrimal sac: A case report (118 visite)
Tumori (ISSN: 0300-8916, 0300-8916print), 2002 Nov; 88(6): 530-531.
Impact Factor: 0.267
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Cante D, Solla R, Manzo R, Chianese E, Punzo G, Cella L, Vassallo P, Morra A, Alterio D, Alberti D, Pacelli R, Canale Cama G
* A case report of a primary NHL of the lacrimal sac (137 visite)
Tumori (ISSN: 0300-8916, 0300-8916print), 2001 Jul; 87(4): 530-531.
Impact Factor: 0.49
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Cella L, Lomax A, Miralbell R
* New techniques in hadrontherapy: Intensity modulated proton beams (99 visite)
Phys Med (ISSN: 1120-1797, 1120-1797linking), 2001; 17(SUPPL.1): 100-102.
Impact Factor: 0.556
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Cella L, Lomax A, Miralbell R
* Potential role of intensity modulated proton beams in prostate cancer radiotherapy (93 visite)
Int J Radiat Oncol (ISSN: 0360-3016, 1879-355x, 1879-355xelectronic), 2001; 49(1): 217-223.
Impact Factor: 3.327
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Cuocolo A, Storto G, Izzo R, Iovino GL, Damiano M, Bertocchi F, Mann J, Trimarco B
Effects of valsartan on left ventricular diastolic function in patients with mild or moderate essential hypertension: Comparison with enalapril (98 visite)
Journal Of Hypertension (ISSN: 0263-6352), 1999 Dec; 17(12): 1759-1766.
Impact Factor: 3.039
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Pavone V, De Simone G, Nastri F, Galdiero S, Staiano N, Lombardi A, Pedone C
Multiple binding mode of reversible synthetic thrombin inhibitors. A comparative structural analysis (204 visite)
Biol Chem Biological Chemistry (ISSN: 1431-6730, 1437-4315), 1998 Sep; 379(8-9): 987-1006.
Impact Factor: 2.636
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Ferrara LA, Iannuzzi R, Gaeta I, Mancini M, Guida L, Marotta T
Left ventricular hypertrophy and hypertension (124 visite)
Clin Exp Hypertens Informa Healthcare, 1996 Jul; 15(6): 1025-1032.
Impact Factor: 0
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Alfano B, Coucourde F, Malgieri F, Ragozzino A
PET/CT and radiotherapy (149 visite)
Q J Nucl Med Mol Imaging, 1980 Oct; 50(1): 4-14.
Impact Factor: 0
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51 Records (47 escludendo Abstract e Conferenze).
Impact factor totale: 148.073 (139.895 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 150.922 (141.726 escludendo Abstract e Conferenze).







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