Multivariate normal tissue complication probability modeling of gastrointestinal toxicity after external beam radiotherapy for localized prostate cancer (354 views)
Radiation Oncology (ISSN: 1748-717x), 2013 Sep 23; 8(1): 221-221.
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Paper type: Journal Article,
Impact factor: 2.36, 5-year impact factor: 2.59
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84884381700&partnerID=40&md5=d12fd25b82e611356f030dd7e4545329
Keywords: Anticoagulant Agent, Antihypertensive Agent, Acute Toxicity, Adult, Article, Cancer Hormone Therapy, Cancer Radiotherapy, Cancer Size, External Beam Radiotherapy, Follow Up, Gastrointestinal Toxicity, Gleason Score, Human, Major Clinical Study, Probability, Prostate Cancer, Radiation Dose, Risk Assessment, Scoring System, Area Under The Curve, Computer Assisted Radiotherapy, Gastrointestinal Tract, Middle Aged, Multivariate Analysis, Procedures, Prostatic Neoplasms, Radiation Injuries, Radiation Response, Radiometry, Receiver Operating Characteristic, Very Elderly, 80 And Over, Area Under Curve, Radiotherapy Dosage, Radiotherapy Planning, Computer-Assisted, Roc Curve,
Affiliations:
*** IBB - CNR ***
Institute of Biostructures and Bioimaging, National Council of Research (CNR), Naples, Italy
Department of Advanced Biomedical Sciences, Federico II University School of Medicine, Naples, Italy
Department of Physics, University Federico II, Naples, Italy
References:
Michalski, J.M., Gay, H., Jackson, A., Radiation dose-volume effects in radiation-induced rectal injury (2010) Int J Radiat Oncol Biol Phys, 76 (3 SUPPL.), pp. S123-S129. , 3319467, 2017150
Cella, L., Lomax, A., Miralbell, R., New techniques in hadrontherapy: intensity modulated proton beams (2001) Phys Med, 17 (SUPPL. 1), pp. 100-102
Skala, M., Rosewall, T., Dawson, L., Patient-assessed late toxicity rates and principal component analysis after image-guided radiation therapy for prostate cancer (2007) Int J Radiat Oncol Biol Phys, 68 (3), pp. 690-698. , 10.1016/j.ijrobp.2006.12.064, 17379434
Efstathiou, J.A., Gray, P.J., Zietman, A.L., Proton beam therapy and localised prostate cancer: current status and controversies (2013) Br J Cancer, 108 (6), pp. 1225-1230. , 10.1038/bjc.2013.100, 23481182
Gulliford, S.L., Partridge, M., Sydes, M.R., Parameters for the Lyman Kutcher Burman (LKB) model of Normal Tissue Complication Probability (NTCP) for specific rectal complications observed in clinical practise (2012) Radiother Oncol, 102 (3), pp. 347-351. , 10.1016/j.radonc.2011.10.022, 22119373
Defraene, G., Van den Bergh, L., Al-Mamgani, A., The benefits of including clinical factors in rectal normal tissue complication probability modeling after radiotherapy for prostate cancer (2012) Int J Radiat Oncol Biol Phys, 82 (3), pp. 1233-1242. , 10.1016/j.ijrobp.2011.03.056, 21664059
Fellin, G., Fiorino, C., Rancati, T., Clinical and dosimetric predictors of late rectal toxicity after conformal radiation for localized prostate cancer: results of a large multicenter observational study (2009) Radiother Oncol, 93 (2), pp. 197-202. , 10.1016/j.radonc.2009.09.004, 19828205
Valdagni, R., Kattan, M.W., Rancati, T., Is it time to tailor the prediction of radio-induced toxicity in prostate cancer patients? Building the first set of nomograms for late rectal syndrome (2012) Int J Radiat Oncol Biol Phys, 82 (5), pp. 1957-1966. , 10.1016/j.ijrobp.2011.03.028, 21640511
Valdagni, R., Vavassori, V., Rancati, T., Increasing the risk of late rectal bleeding after high-dose radiotherapy for prostate cancer: the case of previous abdominal surgery. Results from a prospective trial (2012) Radiother Oncol, 103 (2), pp. 252-255. , 10.1016/j.radonc.2012.03.012, 22521747
Cella, L., Conson, M., Caterino, M., Thyroid V30 predicts radiation-induced hypothyroidism in patients treated with sequential chemo-radiotherapy for Hodgkin's lymphoma (2012) Int J Radiat Oncol Biol Phys, 82 (5), pp. 1802-1808. , 10.1016/j.ijrobp.2010.09.054, 21514076
Cella, L., Liuzzi, R., Conson, M., Multivariate normal tissue complication probability modeling of heart valve dysfunction in hodgkin lymphoma survivors (2013) Int J Radiat Oncol Biol Phys, 87 (2), pp. 304-310. , 10.1016/j.ijrobp.2013.05.049, 23886419
El Naqa, I., Bradley, J., Blanco, A.I., Multivariable modeling of radiotherapy outcomes, including dose-volume and clinical factors (2006) Int J Radiat Oncol Biol Phys, 64 (4), pp. 1275-1286. , 10.1016/j.ijrobp.2005.11.022, 16504765
El Naqa, I., Suneja, G., Lindsay, P.E., Dose response explorer: an integrated open-source tool for exploring and modelling radiotherapy dose-volume outcome relationships (2006) Phys Med Biol, 51 (22), pp. 5719-5735. , 10.1088/0031-9155/51/22/001, 17068361
Gay, H.A., Barthold, H.J., O'Meara, E., Pelvic normal tissue contouring guidelines for radiation therapy: a radiation therapy oncology group consensus panel atlas (2012) Int J Radiat Oncol Biol Phys, 83 (3), pp. e353-e362. , 10.1016/j.ijrobp.2012.01.023, 22483697
Cox, J.D., Stetz, J., Pajak, T.F., Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC) (1995) Int J Radiat Oncol Biol Phys, 31 (5), pp. 1341-1346. , 10.1016/0360-3016(95)00060-C, 7713792
Pacelli, R., Conson, M., Cella, L., Radiation therapy following surgery for localized breast cancer: outcome prediction by classical prognostic factors and approximatedgenetic subtypes (2013) J Radiat Res, 54 (2), pp. 292-298. , 10.1093/jrr/rrs087, 3589925, 23019151
Pedicini, P., Caivano, R., Strigari, L., In regard to Miralbell et al. Re: Dose-fractionation sensitivity of prostate cancer deduced from radiotherapy outcomes of 5969 patients in seven international institutional datasets: alpha/beta = 1.4 (0.9-2.2) Gy (2013) Int J Radiat Oncol Biol Phys, 85 (1), pp. 10-11. , 10.1016/j.ijrobp.2012.03.056, 23237001
Pedicini, P., Strigari, L., Benassi, M., Estimation of a self-consistent set of radiobiological parameters from hypofractionated versus standard radiation therapy of prostate cancer (2013) Int J Radiat Oncol Biol Phys, 85 (5), pp. e231-7. , 10.1016/j.ijrobp.2012.11.033, 23332226
Hamstra, D.A., Stenmark, M.H., Ritter, T., Age and comorbid illness are associated with late rectal toxicity following dose-escalated radiation therapy for prostate cancer (2013) Int J Radiat Oncol Biol Phys, 85 (5), pp. 1246-1253. , 10.1016/j.ijrobp.2012.10.042, 23265567
Trott, K.R., Doerr, W., Facoetti, A., Biological mechanisms of normal tissue damage: importance for the design of NTCP models (2012) Radiother Oncol, 105 (1), pp. 79-85. , 10.1016/j.radonc.2012.05.008, 22748390
van der Schaaf, A., Xu, C.J., van Luijk, P., Multivariate modeling of complications with data driven variable selection: guarding against overfitting and effects of data set size (2012) Radiother Oncol, 105 (1), pp. 115-121. , 10.1016/j.radonc.2011.12.006, 22264894
Heemsbergen, W.D., Peeters, S.T., Koper, P.C., Acute and late gastrointestinal toxicity after radiotherapy in prostate cancer patients: consequential late damage (2006) Int J Radiat Oncol Biol Phys, 66 (1), pp. 3-10. , 10.1016/j.ijrobp.2006.03.055, 16814954
Kharofa, J., Cohen, E.P., Tomic, R., Decreased risk of radiation pneumonitis with incidental concurrent use of angiotensin-converting enzyme inhibitors and thoracic radiation therapy (2012) Int J Radiat Oncol Biol Phys, 84 (1), pp. 238-243. , 10.1016/j.ijrobp.2011.11.013, 22300564
Lee, T.C., Greene-Schloesser, D., Payne, V., Chronic administration of the angiotensin-converting enzyme inhibitor, ramipril, prevents fractionated whole-brain irradiation-induced perirhinal cortex-dependent cognitive impairment (2012) Radiat Res, 178 (1), pp. 46-56. , 10.1667/RR2731.1, 3422865, 22687052
Rehman, A., Schiffrin, E.L., Vascular effects of antihypertensive drug therapy (2010) Curr Hypertens Rep, 12 (4), pp. 226-232. , 10.1007/s11906-010-0117-3, 20514556
Dorr, W., Hendry, J.H., Consequential late effects in normal tissues (2001) Radiother Oncol, 61 (3), pp. 223-231. , 10.1016/S0167-8140(01)00429-7, 11730991
Buettner, F., Gulliford, S.L., Webb, S., Using Bayesian logistic regression to evaluate a new type of dosimetric constraint for prostate radiotherapy treatment planning (2010) Med Phys, 37 (4), pp. 1768-1777. , 10.1118/1.3367013, 20443499
Valdagni, R., Rancati, T., Reducing rectal injury during external beam radiotherapy for prostate cancer (2013) Nat Rev Urol, 10 (6), pp. 345-357. , 10.1038/nrurol.2013.96, 23670182
Loeffler, J.S., Durante, M., Charged particle therapy-optimization, challenges and future directions (2013) Nat Rev Clin Oncol, 10 (7), pp. 411-424. , 10.1038/nrclinonc.2013.79, 23689752
Michalski, J. M., Gay, H., Jackson, A., Radiation dose-volume effects in radiation-induced rectal injury (2010) Int J Radiat Oncol Biol Phys, 76 (3 SUPPL.), pp. S123-S129. , 3319467, 2017150
Efstathiou, J. A., Gray, P. J., Zietman, A. L., Proton beam therapy and localised prostate cancer: current status and controversies (2013) Br J Cancer, 108 (6), pp. 1225-1230. , 10. 1038/bjc. 2013. 100, 23481182
Gulliford, S. L., Partridge, M., Sydes, M. R., Parameters for the Lyman Kutcher Burman (LKB) model of Normal Tissue Complication Probability (NTCP) for specific rectal complications observed in clinical practise (2012) Radiother Oncol, 102 (3), pp. 347-351. , 10. 1016/j. radonc. 2011. 10. 022, 22119373
Gay, H. A., Barthold, H. J., O'Meara, E., Pelvic normal tissue contouring guidelines for radiation therapy: a radiation therapy oncology group consensus panel atlas (2012) Int J Radiat Oncol Biol Phys, 83 (3), pp. e353-e362. , 10. 1016/j. ijrobp. 2012. 01. 023, 22483697
Cox, J. D., Stetz, J., Pajak, T. F., Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC) (1995) Int J Radiat Oncol Biol Phys, 31 (5), pp. 1341-1346. , 10. 1016/0360-3016 (95) 00060-C, 7713792
Hamstra, D. A., Stenmark, M. H., Ritter, T., Age and comorbid illness are associated with late rectal toxicity following dose-escalated radiation therapy for prostate cancer (2013) Int J Radiat Oncol Biol Phys, 85 (5), pp. 1246-1253. , 10. 1016/j. ijrobp. 2012. 10. 042, 23265567
Trott, K. R., Doerr, W., Facoetti, A., Biological mechanisms of normal tissue damage: importance for the design of NTCP models (2012) Radiother Oncol, 105 (1), pp. 79-85. , 10. 1016/j. radonc. 2012. 05. 008, 22748390
Heemsbergen, W. D., Peeters, S. T., Koper, P. C., Acute and late gastrointestinal toxicity after radiotherapy in prostate cancer patients: consequential late damage (2006) Int J Radiat Oncol Biol Phys, 66 (1), pp. 3-10. , 10. 1016/j. ijrobp. 2006. 03. 055, 16814954
Lee, T. C., Greene-Schloesser, D., Payne, V., Chronic administration of the angiotensin-converting enzyme inhibitor, ramipril, prevents fractionated whole-brain irradiation-induced perirhinal cortex-dependent cognitive impairment (2012) Radiat Res, 178 (1), pp. 46-56. , 10. 1667/RR2731. 1, 3422865, 22687052
Loeffler, J. S., Durante, M., Charged particle therapy-optimization, challenges and future directions (2013) Nat Rev Clin Oncol, 10 (7), pp. 411-424. , 10. 1038/nrclinonc. 2013. 79, 23689752
Radiation Oncology (ISSN: 1748-717x), 2013 Sep 23; 8(1): 221-221.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 2.36, 5-year impact factor: 2.59
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84884381700&partnerID=40&md5=d12fd25b82e611356f030dd7e4545329
Keywords: Anticoagulant Agent, Antihypertensive Agent, Acute Toxicity, Adult, Article, Cancer Hormone Therapy, Cancer Radiotherapy, Cancer Size, External Beam Radiotherapy, Follow Up, Gastrointestinal Toxicity, Gleason Score, Human, Major Clinical Study, Probability, Prostate Cancer, Radiation Dose, Risk Assessment, Scoring System, Area Under The Curve, Computer Assisted Radiotherapy, Gastrointestinal Tract, Middle Aged, Multivariate Analysis, Procedures, Prostatic Neoplasms, Radiation Injuries, Radiation Response, Radiometry, Receiver Operating Characteristic, Very Elderly, 80 And Over, Area Under Curve, Radiotherapy Dosage, Radiotherapy Planning, Computer-Assisted, Roc Curve,
Affiliations:
*** IBB - CNR ***
Institute of Biostructures and Bioimaging, National Council of Research (CNR), Naples, Italy
Department of Advanced Biomedical Sciences, Federico II University School of Medicine, Naples, Italy
Department of Physics, University Federico II, Naples, Italy
References:
Michalski, J.M., Gay, H., Jackson, A., Radiation dose-volume effects in radiation-induced rectal injury (2010) Int J Radiat Oncol Biol Phys, 76 (3 SUPPL.), pp. S123-S129. , 3319467, 2017150
Cella, L., Lomax, A., Miralbell, R., New techniques in hadrontherapy: intensity modulated proton beams (2001) Phys Med, 17 (SUPPL. 1), pp. 100-102
Skala, M., Rosewall, T., Dawson, L., Patient-assessed late toxicity rates and principal component analysis after image-guided radiation therapy for prostate cancer (2007) Int J Radiat Oncol Biol Phys, 68 (3), pp. 690-698. , 10.1016/j.ijrobp.2006.12.064, 17379434
Efstathiou, J.A., Gray, P.J., Zietman, A.L., Proton beam therapy and localised prostate cancer: current status and controversies (2013) Br J Cancer, 108 (6), pp. 1225-1230. , 10.1038/bjc.2013.100, 23481182
Gulliford, S.L., Partridge, M., Sydes, M.R., Parameters for the Lyman Kutcher Burman (LKB) model of Normal Tissue Complication Probability (NTCP) for specific rectal complications observed in clinical practise (2012) Radiother Oncol, 102 (3), pp. 347-351. , 10.1016/j.radonc.2011.10.022, 22119373
Defraene, G., Van den Bergh, L., Al-Mamgani, A., The benefits of including clinical factors in rectal normal tissue complication probability modeling after radiotherapy for prostate cancer (2012) Int J Radiat Oncol Biol Phys, 82 (3), pp. 1233-1242. , 10.1016/j.ijrobp.2011.03.056, 21664059
Fellin, G., Fiorino, C., Rancati, T., Clinical and dosimetric predictors of late rectal toxicity after conformal radiation for localized prostate cancer: results of a large multicenter observational study (2009) Radiother Oncol, 93 (2), pp. 197-202. , 10.1016/j.radonc.2009.09.004, 19828205
Valdagni, R., Kattan, M.W., Rancati, T., Is it time to tailor the prediction of radio-induced toxicity in prostate cancer patients? Building the first set of nomograms for late rectal syndrome (2012) Int J Radiat Oncol Biol Phys, 82 (5), pp. 1957-1966. , 10.1016/j.ijrobp.2011.03.028, 21640511
Valdagni, R., Vavassori, V., Rancati, T., Increasing the risk of late rectal bleeding after high-dose radiotherapy for prostate cancer: the case of previous abdominal surgery. Results from a prospective trial (2012) Radiother Oncol, 103 (2), pp. 252-255. , 10.1016/j.radonc.2012.03.012, 22521747
Cella, L., Conson, M., Caterino, M., Thyroid V30 predicts radiation-induced hypothyroidism in patients treated with sequential chemo-radiotherapy for Hodgkin's lymphoma (2012) Int J Radiat Oncol Biol Phys, 82 (5), pp. 1802-1808. , 10.1016/j.ijrobp.2010.09.054, 21514076
Cella, L., Liuzzi, R., Conson, M., Multivariate normal tissue complication probability modeling of heart valve dysfunction in hodgkin lymphoma survivors (2013) Int J Radiat Oncol Biol Phys, 87 (2), pp. 304-310. , 10.1016/j.ijrobp.2013.05.049, 23886419
El Naqa, I., Bradley, J., Blanco, A.I., Multivariable modeling of radiotherapy outcomes, including dose-volume and clinical factors (2006) Int J Radiat Oncol Biol Phys, 64 (4), pp. 1275-1286. , 10.1016/j.ijrobp.2005.11.022, 16504765
El Naqa, I., Suneja, G., Lindsay, P.E., Dose response explorer: an integrated open-source tool for exploring and modelling radiotherapy dose-volume outcome relationships (2006) Phys Med Biol, 51 (22), pp. 5719-5735. , 10.1088/0031-9155/51/22/001, 17068361
Gay, H.A., Barthold, H.J., O'Meara, E., Pelvic normal tissue contouring guidelines for radiation therapy: a radiation therapy oncology group consensus panel atlas (2012) Int J Radiat Oncol Biol Phys, 83 (3), pp. e353-e362. , 10.1016/j.ijrobp.2012.01.023, 22483697
Cox, J.D., Stetz, J., Pajak, T.F., Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC) (1995) Int J Radiat Oncol Biol Phys, 31 (5), pp. 1341-1346. , 10.1016/0360-3016(95)00060-C, 7713792
Pacelli, R., Conson, M., Cella, L., Radiation therapy following surgery for localized breast cancer: outcome prediction by classical prognostic factors and approximatedgenetic subtypes (2013) J Radiat Res, 54 (2), pp. 292-298. , 10.1093/jrr/rrs087, 3589925, 23019151
Pedicini, P., Caivano, R., Strigari, L., In regard to Miralbell et al. Re: Dose-fractionation sensitivity of prostate cancer deduced from radiotherapy outcomes of 5969 patients in seven international institutional datasets: alpha/beta = 1.4 (0.9-2.2) Gy (2013) Int J Radiat Oncol Biol Phys, 85 (1), pp. 10-11. , 10.1016/j.ijrobp.2012.03.056, 23237001
Pedicini, P., Strigari, L., Benassi, M., Estimation of a self-consistent set of radiobiological parameters from hypofractionated versus standard radiation therapy of prostate cancer (2013) Int J Radiat Oncol Biol Phys, 85 (5), pp. e231-7. , 10.1016/j.ijrobp.2012.11.033, 23332226
Hamstra, D.A., Stenmark, M.H., Ritter, T., Age and comorbid illness are associated with late rectal toxicity following dose-escalated radiation therapy for prostate cancer (2013) Int J Radiat Oncol Biol Phys, 85 (5), pp. 1246-1253. , 10.1016/j.ijrobp.2012.10.042, 23265567
Trott, K.R., Doerr, W., Facoetti, A., Biological mechanisms of normal tissue damage: importance for the design of NTCP models (2012) Radiother Oncol, 105 (1), pp. 79-85. , 10.1016/j.radonc.2012.05.008, 22748390
van der Schaaf, A., Xu, C.J., van Luijk, P., Multivariate modeling of complications with data driven variable selection: guarding against overfitting and effects of data set size (2012) Radiother Oncol, 105 (1), pp. 115-121. , 10.1016/j.radonc.2011.12.006, 22264894
Heemsbergen, W.D., Peeters, S.T., Koper, P.C., Acute and late gastrointestinal toxicity after radiotherapy in prostate cancer patients: consequential late damage (2006) Int J Radiat Oncol Biol Phys, 66 (1), pp. 3-10. , 10.1016/j.ijrobp.2006.03.055, 16814954
Kharofa, J., Cohen, E.P., Tomic, R., Decreased risk of radiation pneumonitis with incidental concurrent use of angiotensin-converting enzyme inhibitors and thoracic radiation therapy (2012) Int J Radiat Oncol Biol Phys, 84 (1), pp. 238-243. , 10.1016/j.ijrobp.2011.11.013, 22300564
Lee, T.C., Greene-Schloesser, D., Payne, V., Chronic administration of the angiotensin-converting enzyme inhibitor, ramipril, prevents fractionated whole-brain irradiation-induced perirhinal cortex-dependent cognitive impairment (2012) Radiat Res, 178 (1), pp. 46-56. , 10.1667/RR2731.1, 3422865, 22687052
Rehman, A., Schiffrin, E.L., Vascular effects of antihypertensive drug therapy (2010) Curr Hypertens Rep, 12 (4), pp. 226-232. , 10.1007/s11906-010-0117-3, 20514556
Dorr, W., Hendry, J.H., Consequential late effects in normal tissues (2001) Radiother Oncol, 61 (3), pp. 223-231. , 10.1016/S0167-8140(01)00429-7, 11730991
Buettner, F., Gulliford, S.L., Webb, S., Using Bayesian logistic regression to evaluate a new type of dosimetric constraint for prostate radiotherapy treatment planning (2010) Med Phys, 37 (4), pp. 1768-1777. , 10.1118/1.3367013, 20443499
Valdagni, R., Rancati, T., Reducing rectal injury during external beam radiotherapy for prostate cancer (2013) Nat Rev Urol, 10 (6), pp. 345-357. , 10.1038/nrurol.2013.96, 23670182
Loeffler, J.S., Durante, M., Charged particle therapy-optimization, challenges and future directions (2013) Nat Rev Clin Oncol, 10 (7), pp. 411-424. , 10.1038/nrclinonc.2013.79, 23689752
Michalski, J. M., Gay, H., Jackson, A., Radiation dose-volume effects in radiation-induced rectal injury (2010) Int J Radiat Oncol Biol Phys, 76 (3 SUPPL.), pp. S123-S129. , 3319467, 2017150
Efstathiou, J. A., Gray, P. J., Zietman, A. L., Proton beam therapy and localised prostate cancer: current status and controversies (2013) Br J Cancer, 108 (6), pp. 1225-1230. , 10. 1038/bjc. 2013. 100, 23481182
Gulliford, S. L., Partridge, M., Sydes, M. R., Parameters for the Lyman Kutcher Burman (LKB) model of Normal Tissue Complication Probability (NTCP) for specific rectal complications observed in clinical practise (2012) Radiother Oncol, 102 (3), pp. 347-351. , 10. 1016/j. radonc. 2011. 10. 022, 22119373
Gay, H. A., Barthold, H. J., O'Meara, E., Pelvic normal tissue contouring guidelines for radiation therapy: a radiation therapy oncology group consensus panel atlas (2012) Int J Radiat Oncol Biol Phys, 83 (3), pp. e353-e362. , 10. 1016/j. ijrobp. 2012. 01. 023, 22483697
Cox, J. D., Stetz, J., Pajak, T. F., Toxicity criteria of the Radiation Therapy Oncology Group (RTOG) and the European Organization for Research and Treatment of Cancer (EORTC) (1995) Int J Radiat Oncol Biol Phys, 31 (5), pp. 1341-1346. , 10. 1016/0360-3016 (95) 00060-C, 7713792
Hamstra, D. A., Stenmark, M. H., Ritter, T., Age and comorbid illness are associated with late rectal toxicity following dose-escalated radiation therapy for prostate cancer (2013) Int J Radiat Oncol Biol Phys, 85 (5), pp. 1246-1253. , 10. 1016/j. ijrobp. 2012. 10. 042, 23265567
Trott, K. R., Doerr, W., Facoetti, A., Biological mechanisms of normal tissue damage: importance for the design of NTCP models (2012) Radiother Oncol, 105 (1), pp. 79-85. , 10. 1016/j. radonc. 2012. 05. 008, 22748390
Heemsbergen, W. D., Peeters, S. T., Koper, P. C., Acute and late gastrointestinal toxicity after radiotherapy in prostate cancer patients: consequential late damage (2006) Int J Radiat Oncol Biol Phys, 66 (1), pp. 3-10. , 10. 1016/j. ijrobp. 2006. 03. 055, 16814954
Lee, T. C., Greene-Schloesser, D., Payne, V., Chronic administration of the angiotensin-converting enzyme inhibitor, ramipril, prevents fractionated whole-brain irradiation-induced perirhinal cortex-dependent cognitive impairment (2012) Radiat Res, 178 (1), pp. 46-56. , 10. 1667/RR2731. 1, 3422865, 22687052
Loeffler, J. S., Durante, M., Charged particle therapy-optimization, challenges and future directions (2013) Nat Rev Clin Oncol, 10 (7), pp. 411-424. , 10. 1038/nrclinonc. 2013. 79, 23689752
Multivariate normal tissue complication probability modeling of gastrointestinal toxicity after external beam radiotherapy for localized prostate cancer
Background: The risk of radio-induced gastrointestinal (GI) complications is affected by several factors other than the dose to the rectum such as patient characteristics, hormonal or antihypertensive therapy, and acute rectal toxicity. Purpose of this work is to study clinical and dosimetric parameters impacting on late GI toxicity after prostate external beam radiotherapy (RT) and to establish multivariate normal tissue complication probability (NTCP) model for radiation-induced GI complications.Methods: A total of 57 men who had undergone definitive RT for prostate cancer were evaluated for GI events classified using the RTOG/EORTC scoring system. Their median age was 73 years (range 53-85). The patients were assessed for GI toxicity before, during, and periodically after RT completion. Several clinical variables along with rectum dose-volume parameters (Vx) were collected and their correlation to GI toxicity was analyzed by Spearman's rank correlation coefficient (Rs). Multivariate logistic regression method using resampling techniques was applied to select model order and parameters for NTCP modeling. Model performance was evaluated through the area under the receiver operating characteristic curve (AUC).Results: At a median follow-up of 30 months, 37% (21/57) patients developed G1-2 acute GI events while 33% (19/57) were diagnosed with G1-2 late GI events. An NTCP model for late mild/moderate GI toxicity based on three variables including V65 (OR = 1.03), antihypertensive and/or anticoagulant (AH/AC) drugs (OR = 0.24), and acute GI toxicity (OR = 4.3) was selected as the most predictive model (Rs = 0.47, p < 0.001; AUC = 0.79). This three-variable model outperforms the logistic model based on V65 only (Rs = 0.28, p < 0.001; AUC = 0.69).Conclusions: We propose a logistic NTCP model for late GI toxicity considering not only rectal irradiation dose but also clinical patient-specific factors. Accordingly, the risk of G1-2 late GI increases as V65 increases, it is higher for patients experiencing previous acute toxicity and it is lower for patients who take AH/AC drugs. The developed NTCP model could represent a potentially useful tool to be used in prospective trial and for comparison among different RT techniques. © 2013 Cella et al.; licensee BioMed Central Ltd.
Background: The risk of radio-induced gastrointestinal (GI) complications is affected by several factors other than the dose to the rectum such as patient characteristics, hormonal or antihypertensive therapy, and acute rectal toxicity. Purpose of this work is to study clinical and dosimetric parameters impacting on late GI toxicity after prostate external beam radiotherapy (RT) and to establish multivariate normal tissue complication probability (NTCP) model for radiation-induced GI complications.Methods: A total of 57 men who had undergone definitive RT for prostate cancer were evaluated for GI events classified using the RTOG/EORTC scoring system. Their median age was 73 years (range 53-85). The patients were assessed for GI toxicity before, during, and periodically after RT completion. Several clinical variables along with rectum dose-volume parameters (Vx) were collected and their correlation to GI toxicity was analyzed by Spearman's rank correlation coefficient (Rs). Multivariate logistic regression method using resampling techniques was applied to select model order and parameters for NTCP modeling. Model performance was evaluated through the area under the receiver operating characteristic curve (AUC).Results: At a median follow-up of 30 months, 37% (21/57) patients developed G1-2 acute GI events while 33% (19/57) were diagnosed with G1-2 late GI events. An NTCP model for late mild/moderate GI toxicity based on three variables including V65 (OR = 1.03), antihypertensive and/or anticoagulant (AH/AC) drugs (OR = 0.24), and acute GI toxicity (OR = 4.3) was selected as the most predictive model (Rs = 0.47, p < 0.001; AUC = 0.79). This three-variable model outperforms the logistic model based on V65 only (Rs = 0.28, p < 0.001; AUC = 0.69).Conclusions: We propose a logistic NTCP model for late GI toxicity considering not only rectal irradiation dose but also clinical patient-specific factors. Accordingly, the risk of G1-2 late GI increases as V65 increases, it is higher for patients experiencing previous acute toxicity and it is lower for patients who take AH/AC drugs. The developed NTCP model could represent a potentially useful tool to be used in prospective trial and for comparison among different RT techniques. © 2013 Cella et al.; licensee BioMed Central Ltd.
Multivariate normal tissue complication probability modeling of gastrointestinal toxicity after external beam radiotherapy for localized prostate cancer
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Multivariate normal tissue complication probability modeling of gastrointestinal toxicity after external beam radiotherapy for localized prostate cancer
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Riccardi C, Napolitano E, Platella C, Musumeci D, Montesarchio D
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Porcellini M, Mainenti PP, Bracale U
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Cante D, Solla R, Manzo R, Chianese E, Punzo G, Cella L, Vassallo P, Morra A, Alterio D, Alberti D, Pacelli R, Canale Cama G
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Cella L, Lomax A, Miralbell R
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Cella L, Lomax A, Miralbell R
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Cuocolo A, Storto G, Izzo R, Iovino GL, Damiano M, Bertocchi F, Mann J, Trimarco B
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Pavone V, De Simone G, Nastri F, Galdiero S, Staiano N, Lombardi A, Pedone C
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Ferrara LA, Iannuzzi R, Gaeta I, Mancini M, Guida L, Marotta T
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Alfano B, Coucourde F, Malgieri F, Ragozzino A
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Q J Nucl Med Mol Imaging, 1980 Oct; 50(1): 4-14.
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Impact Factor: 11.127
View Export to BibTeX Export to EndNote
Russo M, Malandrino P, Moleti M, Vermiglio F, D'Angelo A, La Rosa G, Sapuppo G, Calaciura F, Regalbuto C, Belfiore A, Vigneri R, Pellegriti G
* Differentiated thyroid cancer in children: Heterogeneity of predictive risk factors (263 views)
Pediatr Blood Cancer (ISSN: 1545-5009linking), 2018 Sep; 65(9): e27226-e27226.
Impact Factor: 2.513
View Export to BibTeX Export to EndNote
Cennamo G, Rossi C, Breve MA, Velotti N, Farella A, Liuzzi R, Cennamo G
* Evaluation of vascular changes with optical coherence tomography angiography after ruthenium-106 brachytherapy of circumscribed choroidal hemangioma (238 views)
Eye (ISSN: 0950-222xlinking, 1476-5454electronic), 2018 Aug; 32(8): 1401-1405.
Impact Factor: 2.275
View Export to BibTeX Export to EndNote
Salvatore B, D'Amico D, Fonti R
* Metastasis to the Sellar/Suprasellar Region in a Patient With Endometrial Carcinoma Detected by 18F-FDG PET/CT (287 views)
Clin Nucl Med (ISSN: 1536-0229electronic, 0363-9762linking), 2018 May; 43(5): 363-364.
Impact Factor: 0.253
View Export to BibTeX Export to EndNote
Alterio D, Gerardi MA, Cella L, Spoto R, Zurlo V, Sabbatini A, Fodor C, D'Avino V, Conson M, Valoriani F, Ciardo D, Pacelli R, Ferrari A, Maisonneuve P, Preda L, Bruschini R, Cossu Rocca M, Rondi E, Colangione S, Palma G, Dicuonzo S, Orecchia R, Sanguineti G, Jereczek-fossa BA
* Radiation-induced acute dysphagia: Prospective observational study on 42 head and neck cancer patients (421 views)
Strahlenther Onkol (ISSN: 0179-7158, 0179-7158linking), 2017 Sep 07; 193(11): 971-981.
Impact Factor: 2.459
View Export to BibTeX Export to EndNote
D'Avino V, Palma G, Liuzzi R, Conson M, Doria F, Salvatore M, Pacelli R, Cella L
* Prediction of gastrointestinal toxicity after external beam radiotherapy for localized prostate cancer (369 views)
Radiat Oncol (ISSN: 1748-717x), 2015 Apr 8; 10(1): 80-80.
Impact Factor: 2.466
View Export to BibTeX Export to EndNote
Cella L, Oh JH, Deasy JO, Palma G, Liuzzi R, D'Avino V, Conson M, Picardi M, Salvatore M, Pacelli R
* Predicting radiation-induced valvular heart damage (307 views)
Acta Oncol (ISSN: 0284-186x, 0284-186xlinking), 2015 Mar 24; 54(10): 1796-1804.
Impact Factor: 3.73
View Export to BibTeX Export to EndNote
Perri F, Pacelli R, Della Vittoria Scarpati G, Cella L, Giuliano M, Caponigro F, Pepe S
* Radioresistance in head and neck squamous cell carcinoma: Biological bases and therapeutic implications (454 views)
Head Neck-J Sci Spec (ISSN: 1043-3074), 2015; 37(5): 763-770.
Impact Factor: 2.76
View Export to BibTeX Export to EndNote
Formicola F, Riccardi A, Vigliar E, Biondi B, Accurso A, Del Vecchio W, Imbriaco M
* Multimetastatic medullary thyroid carcinoma to the breast: PET/CT--mammographic-US and MR findings (241 views)
Breast J (ISSN: 1075-122x), 2014 Nov; 20(6): 653-654.
Impact Factor: 1.411
View Export to BibTeX Export to EndNote
Pedicini P, Fiorentino A, Simeon V, Tini P, Chiumento C, Pirtoli L, Salvatore M, Storto G
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Strahlenther Onkol (ISSN: 0179-7158, 0179-7158linking), 2014 Oct; 190(10): 925-932.
Impact Factor: 2.914
View Export to BibTeX Export to EndNote
Gallicchio R, Giacomobono S, Nardelli A, Pellegrino T, Simeon V, Gattozzi D, Maddalena F, Mainenti PP, Storto G
* Palliative Treatment Of Bone Metastases With Samarium-153 Edtmp At Onset Of Pain (369 views)
J Bone Miner Metab (ISSN: 0914-8779), 2014 Jul; 32(4): 434-440.
Impact Factor: 2.46
View Export to BibTeX Export to EndNote
Cella L, Liuzzi R, D'Avino V, Conson M, Di Biase A, Picardi M, Pugliese N, Solla R, Salvatore M, Pacelli R
* Pulmonary damage in Hodgkin's lymphoma patients treated with sequential chemo-radiotherapy: Predictors of radiation-induced lung injury (305 views)
Acta Oncol (ISSN: 0284-186x), 2014 May; 53(5): 613-619.
Impact Factor: 2.997
View Export to BibTeX Export to EndNote
Dynkevich Y, Rother KI, Whitford I, Qureshi S, Galiveeti S, Szulc AL, Danoff A, Breen TL, Kaviani N, Shanik MH, LeRoith D, Vigneri R, Koch CA, Roth J
* Tumors, IGF-2, and Hypoglycemia: Insights From the Clinic, the Laboratory, and the Historical Archive (1417 views)
Endocrine Reviews (ISSN: 0163-769x), 2013 Dec; 34(6): 798-826.
Impact Factor: 19.358
View Export to BibTeX Export to EndNote
Pedicini P, Fiorentino A, Improta G, Nappi A, Salvatore M, Storto G
* Estimate of the accelerated proliferation by protein tyrosine phosphatase (PTEN) over expression in postoperative radiotherapy of head and neck squamous cell carcinoma (280 views)
Clin Transl Oncol (ISSN: 1699-048x), 2013 Nov; 15(11): 919-924.
Impact Factor: 1.6
View Export to BibTeX Export to EndNote
Passaro C, Abagnale A, Libertini S, Volpe M, Botta G, Cella L, Pacelli R, Halldèn G, Gillespie D, Portella G
* Ionizing radiation enhances dl922-947-mediated cell death of anaplastic thyroid carcinoma cells (408 views)
Endocr Relat Cancerendocrine Related Cancer (ISSN: 1351-0088), 2013 Sep 19; 20(5): 633-647.
Impact Factor: 4.907
View Export to BibTeX Export to EndNote
Storto G, Gallicchio R, Pellegrino T, Nardelli A, Capacchione D, Sirignano C, Pace L
* Impact of F-18-fluoride PET-CT on implementing early treatment of painful bone metastases with Sm-153 EDTMP (324 views) (PDF 6 views)
Nucl Med Biol (ISSN: 0969-8051, 0883-2897, 0969-8051linking), 2013 May; 40(4): 518-523.
Impact Factor: 2.408
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Cella L, Conson M, Pressello MC, Molinelli S, Schneider U, Donato V, Orecchia R, Salvatore M, Pacelli R
* Hodgkin's lymphoma emerging radiation treatment techniques: Trade-offs between late radio-induced toxicities and secondary malignant neoplasms (366 views)
Radiat Oncol Radiation Oncology (ISSN: 1748-717x), 2013 Jan 30; 8(1): 22-22.
Impact Factor: 2.36
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Cella L, Liuzzi R, Conson M, D'Avino V, Salvatore M, Pacelli R
* Development of multivariate NTCP models for radiation-induced hypothyroidism: A comparative analysis (435 views) (PDF 227 views)
Radiat Oncol Radiation Oncology (ISSN: 1748-717x), 2012 Dec 27; 7(1): 224-224.
Impact Factor: 2.107
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Pedicini P, Nappi A, Strigari L, Jereczek-Fossa BA, Alterio D, Cremonesi M, Botta F, Vischioni B, Caivano R, Fiorentino A, Improta G, Storto G, Benassi M, Orecchia R, Salvatore M
* Correlation between EGFr expression and accelerated proliferation during radiotherapy of head and neck squamous cell carcinoma (415 views)
Radiation Oncology (ISSN: 1748-717x), 2012 Sep 24; 7: 143-143.
Impact Factor: 2.107
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Elefante A, Peca C, Del Basso DCM, Russo C, Formicola F, Mariniello G, Brunetti A, Maiuri F
* Symptomatic spinal cord metastasis from cerebral oligodendroglioma (297 views)
Neurol Sci (ISSN: 1590-1874, 1590-3478, 1590-1874linking), 2012 Jun; 33(3): 609-613.
Impact Factor: 1.412
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Orditura M, Galizia G, Morgillo F, Martinelli E, Lieto E, Vitiello F, Di Martino N, Pacelli R, Renda A, Ciardiello F, De Vita F
* Complete Response To Preoperative Chemoradiation And Survival In Esophageal Cancer: A Pooled Analysis Of Three Single-Institution Phase Ii Trials (379 views)
Diseases Of The Esophagus, 2012 Feb; 142(5): 130-136.
Impact Factor: 2.057
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Cella L, Liuzzi R, Conson M, Torre G, Caterino M, De Rosa N, Picardi M, Camera L, Solla R, Farella A, Salvatore M, Pacelli R
* Dosimetric predictors of asymptomatic heart valvular dysfunction following mediastinal irradiation for Hodgkin's lymphoma (414 views)
Radiother Oncol (ISSN: 0167-8140, 1879-0887, 1879-0887electronic), 2011 Nov; 101(2): 316-321.
Impact Factor: 5.58
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Piazza O, De Robertis E, Caranci F, Quarantelli M, Tufano R
* Riedel's thyroiditis and cerebral venous sinuses thrombosis: A case report (259 views)
Panminerva Med (ISSN: 0031-0808, 1827-1898electronic, 0031-0808linking), 2010 Dec; 52(4): 362-364.
Impact Factor: 1.957
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Strianese D, Tranfa F, Finelli M, De Renzo A, Staibano S, Schiemer R, Cardone D, Pacelli R, Perna F, Mascolo M, De Rosa G, Bonavolonta G
* Hepatitis C virus infection in ocular adnexal lymphomas (323 views)
Arch Ophthalmol (ISSN: 1538-3601, 0003-9950), 2010 Oct; 128(10): 1295-1299.
Impact Factor: 3.516
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Bombardieri E, Ambrosini V, Aktolun C, Baum RP, Bishof-delaloye A, Del Vecchio S, Maffioli L, Mortelmans L, Oyen W, Pepe G, Chiti A
* In-111-pentetreotide scintigraphy: procedure guidelines for tumour imaging (453 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2010 Jul; 37(7): 1441-1448.
Impact Factor: 5.036
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Cella L, Liuzzi R, Magliulo M, Conson M, Camera L, Salvatore M, Pacelli R
* Radiotherapy of large target volumes in Hodgkin's lymphoma: Normal tissue sparing capability of forward IMRT versus conventional techniques (424 views) (PDF 227 views)
Radiat Oncol Radiation Oncology (ISSN: 1748-717x), 2010 May 11; 5(1): 33-33.
Impact Factor: 2.409
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Storto G, De Renzo A, Pellegrino T, Perna F, De Falco T, Erra P, Nardelli A, Speranza A, Klain M, Rotoli B, Pace L
* Assessment of Metabolic Response to Radioimmunotherapy with (90)Y-Ibritumomab Tiuxetan in Patients with Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma (377 views)
Radiology (ISSN: 0033-8419, 1527-1315, 0033-8419linking), 2010 Jan; 254(1): 245-252.
Impact Factor: 6.069
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De Cicco L, Cella L, Liuzzi R, Solla R, Farella A, Punzo G, Tranfa F, Strianese D, Conson M, Bonavolontà G, Salvatore M, Pacelli R
* Radiation therapy in primary orbital lymphoma: A single institution retrospective analysis (450 views)
Radiat Oncol Radiation Oncology (ISSN: 1748-717x), 2009 Dec 7; 4(1): 60-60.
Impact Factor: 2.36
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Peca C, Pacelli R, Elefante A, Del Basso De Caro ML, Vergara P, Mariniello G, Giamundo A, Maiuri F
* Early clinical and neuroradiological worsening after radiotherapy and concomitant temozolomide in patients with glioblastoma: Tumour progression or radionecrosis? (332 views)
Clin Neurol Neurosurg (ISSN: 0303-8467), 2009 May; 111(4): 331-334.
Impact Factor: 1.303
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Storto G, Nicolai E, Salvatore M
* [18F]FDG-PET-CT for early monitoring of tumor response: When and why (357 views)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2009 Apr; 53(2): 167-180.
Impact Factor: 1.724
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Pedone C, Di Pasquale G, Greco C, Gonzini L, Maggioni AP, Pavesi PC, Sabini A, Boccanelli A; In-Acs Outcome Investigators
* Prescription at discharge of recommended treatments for secondary prevention in patients with ST-segment elevation myocardial infarction according to reperfusion strategies. Results from the IN-ACS outcome study (349 views)
Acute Cardiac Care (ISSN: 1748-295x, 1748-2941), 2009; 11(4): 222-228.
Impact Factor: 0
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De Bonis S, Rendina D, Vargas G, Minno DD, Piedimonte V, Gallotta G, Postiglione A
* Predictors of In-Hospital and Long-Term Clinical Outcome in Elderly Patients with Massive Pulmonary Embolism Receiving Thrombolytic Therapy (312 views)
J Am Geriatr Soc (ISSN: 0002-8614), 2008 Dec; 56(12): 2273-2277.
Impact Factor: 3.805
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Hesse B, Lindhardt TB, Acampa W, Anagnostopoulos C, Ballinger J, Bax JJ, Edenbrandt L, Flotats A, Germano G, Stopar TG, Franken P, Kelion A, Kjaer A, Le Guludec D, Ljungberg M, Maenhout AF, Marcassa C, Marving J, Mckiddie F, Schaefer WM, Stegger L, Underw
* EANM/ESC guidelines for radionuclide imaging of cardiac function (526 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2008 Apr; 35(4): 851-885.
Impact Factor: 4.532
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Picardi M, De Renzo A, Pane F, Nicolai E, Pacelli R, Salvatore M, Rotoli B
* Randomized comparison of consolidation radiation versus observation in bulky Hodgkin's lymphoma with post-chemotherapy negative positron emission tomography scans (369 views)
Leuk Lymphoma (ISSN: 1042-8194, 1026-8022linking), 2007 Sep; 48(9): 1721-1727.
Impact Factor: 1.512
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Catalano L, Del Vecchio S, Petruzziello F, Fonti R, Salvatore B, Martorelli C, Califano C, Caparrotti G, Segreto S, Pace L, Rotoli B
* Sestamibi and FDG-PET scans to support diagnosis of jaw osteonecrosis (387 views)
Ann Hematol (ISSN: 0939-5555, 0939-5555linking), 2007 Jun; 86(6): 415-423.
Impact Factor: 2.342
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Iaccarino G, Izzo R, Trimarco V, Cipolletta E, Lanni F, Sorriento D, Iovino GL, Rozza F, De Luca N, Priante O, Di Renzo G, Trimarco B
* β 2-Adrenergic receptor polymorphisms and treatment-induced regression of left ventricular hypertrophy in hypertension (360 views)
Clin Pharmacol Ther Clinical Pharmacology And Therapeutics (ISSN: 0009-9236), 2006; 80(6): 633-645.
Impact Factor: 8.066
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Porcellini M, Mainenti PP, Bracale U
* Endograft repair of spontaneous infrarenal abdominal aortic dissection (154 views)
Journal Of Vascular Surgery (ISSN: 0741-5214), 2005 Jan; 41(1): 155-155.
Impact Factor: 3.173
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Portella G, Pacelli R, Libertini S, Cella L, Vecchio G, Salvatore M, Fusco A
* ONYX-015 Enhances Radiation-Induced Death of Human Anaplastic Thyroid Carcinoma Cells (422 views)
J Clin Endocrinol Metab Journal Of Clinical Endocrinology And Metabolism (ISSN: 0021-972x), 2003 Oct 1; 88(10): 5027-5032.
Impact Factor: 5.873
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Del Vecchio S, Zannetti A, Aloj L, Caracò C, Ciarmiello A, Salvatore M
* Inhibition of early Tc-99m-MIBI uptake by Bcl-2 anti-apoptotic protein overexpression in untreated breast carcinoma (496 views)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2003 Jun; 30(6): 879-887.
Impact Factor: 3.324
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Lomax AJ, Cella L, Weber D, Kurtz JM, Miralbell R
* Potential role of IMRT and protons in the treatment of the breast and regional nodes (319 views)
Int J Rad Oncol Biol Phys, 2003 Mar 1; 48(3Supplement): 785-792.
Impact Factor: 0.155
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Del Vecchio S, Zannetti A, Aloj L, Salvatore M
* MIBI as prognostic factor in breast cancer (425 views)
Q J Nucl Med (ISSN: 1124-3937, 1125-0135), 2003 Mar; 47(1): 46-50.
Impact Factor: 2.222
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Lomax AJ, Cella L, Weber D, Kurtz JM, Miralbell R
* Potential role of intensity-modulated photons and protons in the treatment of the breast and regional nodes (326 views)
Int J Radiat Oncol (ISSN: 0360-3016, 1879-355x, 1879-355xelectronic), 2003; 55(3): 785-792.
Impact Factor: 4.285
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Cama G, Vassallo P, Alberti D, Cante D, Solla R, Punzo G, Cella L, Pacelli R
* Primary non-Hodgkin's lymphoma of the lacrimal sac: A case report (383 views)
Tumori (ISSN: 0300-8916, 0300-8916print, 0300-8916linking), 2002 Nov; 88(6): 530-531.
Impact Factor: 0.267
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Cante D, Solla R, Manzo R, Chianese E, Punzo G, Cella L, Vassallo P, Morra A, Alterio D, Alberti D, Pacelli R, Canale Cama G
* A case report of a primary NHL of the lacrimal sac (388 views)
Tumori (ISSN: 0300-8916, 0300-8916print, 0300-8916linking), 2001 Jul; 87(4): 530-531.
Impact Factor: 0.49
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Cella L, Lomax A, Miralbell R
* New techniques in hadrontherapy: Intensity modulated proton beams (245 views)
Phys Med (ISSN: 1120-1797, 1120-1797linking), 2001; 17(SUPPL.1): 100-102.
Impact Factor: 0.556
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Cella L, Lomax A, Miralbell R
* Potential role of intensity modulated proton beams in prostate cancer radiotherapy (303 views)
Int J Radiat Oncol (ISSN: 0360-3016, 1879-355x, 1879-355xelectronic), 2001; 49(1): 217-223.
Impact Factor: 3.327
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Cuocolo A, Storto G, Izzo R, Iovino GL, Damiano M, Bertocchi F, Mann J, Trimarco B
Effects of valsartan on left ventricular diastolic function in patients with mild or moderate essential hypertension: Comparison with enalapril (273 views)
Journal Of Hypertension (ISSN: 0263-6352), 1999 Dec; 17(12): 1759-1766.
Impact Factor: 3.039
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Pavone V, De Simone G, Nastri F, Galdiero S, Staiano N, Lombardi A, Pedone C
Multiple binding mode of reversible synthetic thrombin inhibitors. A comparative structural analysis (571 views)
Biol Chem Biological Chemistry (ISSN: 1431-6730, 1437-4315), 1998 Sep; 379(8-9): 987-1006.
Impact Factor: 2.636
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Ferrara LA, Iannuzzi R, Gaeta I, Mancini M, Guida L, Marotta T
Left ventricular hypertrophy and hypertension (334 views)
Clin Exp Hypertens Informa Healthcare, 1996 Jul; 15(6): 1025-1032.
Impact Factor: 0
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Alfano B, Coucourde F, Malgieri F, Ragozzino A
PET/CT and radiotherapy (2585 views)
Q J Nucl Med Mol Imaging, 1980 Oct; 50(1): 4-14.
Impact Factor: 0
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50 Records (46 excluding Abstracts).
Total impact factor: 155.239 (147.061 excluding Abstracts).
Total 5 year impact factor: 155.829 (146.633 excluding Abstracts).
Total impact factor: 155.239 (147.061 excluding Abstracts).
Total 5 year impact factor: 155.829 (146.633 excluding Abstracts).
354 views. Last view on Sunday 19 June 2022, 8:54:22
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