Ultrasensitive detection of non-amplified genomic DNA by nanoparticle-enhanced surface plasmon resonance imaging (237 views visite)
Biosens Bioelectron (ISSN: 0956-5663, 1873-4235electronic), 2010 May 15; 25(9): 2095-2100.
Export to Esporta in BibTeX Export to Esporta in EndNote
Paper type Tipo di articolo: Journal Article,
Impact factor: 5.361, 5-year impact factor Impact factor a 5 anni: 5.397
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-77951622977&partnerID=40&md5=0197784a9f4f3c1c0364eb8176933242
Keywords Parole chiave: Biosensors, Dna Sensing, Genomic Dna, Pcr-Free, Peptide Nucleic Acids, Surface-Plasmon Resonance, Biosensing, Certified Reference Materials, Detection Methods, Direct Detection, Dna Detection, Enhanced Surface, Genetically Modified, Labeling Steps, Selectivity And Sensitivity, Target Sequences, Ultrasensitive Detection, Biomolecules, Dna Sequences, Nanoparticles, Polymerase Chain Reaction, Surface Plasmon Resonance, Complementary Dna, Analytic Method, Controlled Study, Dna Determination, Gene Amplification, Gene Targeting, Image Enhancement, Sensitivity Analysis, Base Sequence, Recombinant, Gold, Metal Nanoparticles, Plants, Soybeans,
Affiliations Affiliazioni:
*** IBB - CNR ***
Dipartimento di Scienze Chimiche, Università di Catania, Viale Andrea Doria 6, I-95125 Catania, Italy
Dipartimento di Chimica Organica ed Industriale, Università di Parma, Viale G.P. Usberti 17/a, I-43100 Parma, Italy
Neotron S.p.a., Stradello Aggazzotti 104, I-41010 Modena, Italy
Scuola Superiore di Catania, C/o Dipartimento di Scienze Chimiche, Università di Catania, Viale Andrea Doria 6, Catania, Italy
Istituto Biostrutture e Bioimmagini, CNR, Viale A. Doria 6, Catania, Italy
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Arena, G., Contino, A., Longo, E., Sgarlata, C., Spoto, G., Zito, V., (2004) Chem. Commun., 16, pp. 1812-181
Berdal, K.G., Bøydler, C., Tengs, T., Holst-Jensen, A., (2008) Eur. Food Res. Technol., 227, pp. 1149-1157
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D'Agata, R., Corradini, R., Grasso, G., Marchelli, R., Spoto, G., (2008) ChemBioChem, 9, pp. 2067-2070
D'Agata, R., Grasso, G., Iacono, G., Spoto, G., Vecchio, G., (2006) Org. Biomol. Chem., 4, pp. 610-612
Dos Santos Riccardi, C., Kranz, C., Kowalik, J., Yamanaka, H., Mizaikoff, B., Josowicz, M., (2008) Anal. Chem., 80, pp. 237-245
Germini, A., Rossi, S., Zanetti, A., Corradini, R., Fogher, C., Marchelli, R., (2005) J. Agric. Food Chem., 53, pp. 3958-3962
Gibson, G., (2008) Nat. Rev. Genet., 9, pp. 575-581
(2009), http://ec.europa.eu/food/dyna/gm_register/index_en.cfm, GM Food & Feed, Community Register of GM Food and Feed, Event MON 40-3-2. (accessed 20.11.09)Goodrich, T.T., Lee, H.J., Corn, R.M., (2004) J. Am. Chem. Soc., 126, pp. 4086-4087
Grabar, K.C., Freeman, R.G., Hommer, M.B., Natan, M.J., (1995) Anal. Chem., 67, pp. 735-743
Grasso, G., Bush, A.I., D'Agata, R., Rizzarelli, E., Spoto, G., (2009) Eur. Biophys. J., Biophys. Lett., 38, pp. 407-414
Grasso, G., D'Agata, R., Zanoli, L., Spoto, G., (2009) Microchem. J., 93, pp. 82-86
Grasso, G., Fragai, M., Rizzarelli, E., Spoto, G., Yeo, K.J., (2006) J. Mass Spectrom., 41, pp. 1561-1569
Haiss, W., Thanh, N.T.K., Aveyard, J., Fernig, D.G., (2007) Anal. Chem., 79, pp. 4215-4221
He, L., Musick, M.D., Nicewarner, S.R., Salinas, F.G., Benkovic, S.J., Natan, M.J., Keating, C.D., (2000) J. Am. Chem. Soc., 122, pp. 9071-9077
Ho, H.A., Doré, K., Boissinot, M., Bergeron, M.G., Tanguay, R.M., Boudreau, D., Leclerc, M., (2005) J. Am. Chem. Soc., 127, pp. 12673-12676
(2005), ISO 21569:, Foodstuffs - Methods of Analysis for the Detection of Genetically Modified Organisms and Derived Products - Qualitative Nucleic Acid Based Methods(2005), ISO 21570:, Foodstuffs - Methods of Analysis for the Detection of Genetically Modified Organisms and Derived Products - Quantitative Nucleic Acid Based MethodsLee, H.J., Wark, A.W., Corn, A.W., (2006) Langmuir, 22, pp. 5241-5250
Li-Qiang, C., Foerch, R., Knoll, W., (2007) Angew. Chem. Int. Ed., 46, pp. 4944-4947
Minunni, M., Tombelli, S., Mascini, M., (2007) Anal. Lett., 40, pp. 1360-1370
Perkel, J., (2008) Nat. Methods, 5, pp. 447-453
Rosi, N.L., Mirkin, C.A., (2005) Chem. Rev., 105, pp. 1547-1562
Rossi, S., Scaravelli, E., Germini, A., Corradini, R., Fogher, C., Marchelli, R., (2006) Eur. Food Res. Technol., 223, pp. 1-6
Rothenhäusler, B., Knoll, W., (1988) Nature, 332, pp. 615-617
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Sohni, Y., Kanjilal, S., Kapur, V., (2008) Clin. Biochem., 41, pp. 640-644
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Storhoff, J.J., Lucas, A.D., Garimella, V., Bao, Y.P., Müller, U.R., (2004) Nat. Biotechnol., 22, pp. 883-887
Sujit, K.G., Tarasankar, P., (2007) Chem. Rev., 107, pp. 4797-4862
Totsingan, F., Rossi, S., Corradini, R., Tedeschi, T., Sforza, S., Juris, A., Scaravelli, E., Marchelli, R., (2008) Org. Biomol. Chem., 6, pp. 1232-1237
Wark, A.W., Lee, H.J., Corn, R.M., (2008) Angew. Chem. Int. Ed., 47, pp. 644-652
Yang, K., Moon, J.-K., Jeong, N., Back, K., Kim, H.M., Jeong, S.C., (2008) Genomics, 92, pp. 52-59
Zanoli, L., D'Agata, R., Spoto, G., (2008) Minerva Biotechnol., 20, pp. 165-174
Zhang, N., Appella, D.H., (2007) J. Am. Chem. Soc., 129, pp. 8424-8425
Zhao, W., Brook, M.A., Li, Y.F., (2008) ChemBioChem, 9, pp. 2363-2371
Zhu, D., Tang, Y., Xing, D., Chen, W.R., (2008) Anal. Chem., 80, pp. 3566-3571
Biosens Bioelectron (ISSN: 0956-5663, 1873-4235electronic), 2010 May 15; 25(9): 2095-2100.
Export to Esporta in BibTeX Export to Esporta in EndNote
Paper type Tipo di articolo: Journal Article,
Impact factor: 5.361, 5-year impact factor Impact factor a 5 anni: 5.397
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-77951622977&partnerID=40&md5=0197784a9f4f3c1c0364eb8176933242
Keywords Parole chiave: Biosensors, Dna Sensing, Genomic Dna, Pcr-Free, Peptide Nucleic Acids, Surface-Plasmon Resonance, Biosensing, Certified Reference Materials, Detection Methods, Direct Detection, Dna Detection, Enhanced Surface, Genetically Modified, Labeling Steps, Selectivity And Sensitivity, Target Sequences, Ultrasensitive Detection, Biomolecules, Dna Sequences, Nanoparticles, Polymerase Chain Reaction, Surface Plasmon Resonance, Complementary Dna, Analytic Method, Controlled Study, Dna Determination, Gene Amplification, Gene Targeting, Image Enhancement, Sensitivity Analysis, Base Sequence, Recombinant, Gold, Metal Nanoparticles, Plants, Soybeans,
Affiliations Affiliazioni:
*** IBB - CNR ***
Dipartimento di Scienze Chimiche, Università di Catania, Viale Andrea Doria 6, I-95125 Catania, Italy
Dipartimento di Chimica Organica ed Industriale, Università di Parma, Viale G.P. Usberti 17/a, I-43100 Parma, Italy
Neotron S.p.a., Stradello Aggazzotti 104, I-41010 Modena, Italy
Scuola Superiore di Catania, C/o Dipartimento di Scienze Chimiche, Università di Catania, Viale Andrea Doria 6, Catania, Italy
Istituto Biostrutture e Bioimmagini, CNR, Viale A. Doria 6, Catania, Italy
References Riferimenti:
Arena, G., Contino, A., Longo, E., Sgarlata, C., Spoto, G., Zito, V., (2004) Chem. Commun., 16, pp. 1812-181
Berdal, K.G., Bøydler, C., Tengs, T., Holst-Jensen, A., (2008) Eur. Food Res. Technol., 227, pp. 1149-1157
Burns, C., Spendel, W.U., Puckett, S., Pacey, G.E., (2006) Talanta, 69, pp. 873-876
D'Agata, R., Corradini, R., Grasso, G., Marchelli, R., Spoto, G., (2008) ChemBioChem, 9, pp. 2067-2070
D'Agata, R., Grasso, G., Iacono, G., Spoto, G., Vecchio, G., (2006) Org. Biomol. Chem., 4, pp. 610-612
Dos Santos Riccardi, C., Kranz, C., Kowalik, J., Yamanaka, H., Mizaikoff, B., Josowicz, M., (2008) Anal. Chem., 80, pp. 237-245
Germini, A., Rossi, S., Zanetti, A., Corradini, R., Fogher, C., Marchelli, R., (2005) J. Agric. Food Chem., 53, pp. 3958-3962
Gibson, G., (2008) Nat. Rev. Genet., 9, pp. 575-581
(2009), http://ec.europa.eu/food/dyna/gm_register/index_en.cfm, GM Food & Feed, Community Register of GM Food and Feed, Event MON 40-3-2. (accessed 20.11.09)Goodrich, T.T., Lee, H.J., Corn, R.M., (2004) J. Am. Chem. Soc., 126, pp. 4086-4087
Grabar, K.C., Freeman, R.G., Hommer, M.B., Natan, M.J., (1995) Anal. Chem., 67, pp. 735-743
Grasso, G., Bush, A.I., D'Agata, R., Rizzarelli, E., Spoto, G., (2009) Eur. Biophys. J., Biophys. Lett., 38, pp. 407-414
Grasso, G., D'Agata, R., Zanoli, L., Spoto, G., (2009) Microchem. J., 93, pp. 82-86
Grasso, G., Fragai, M., Rizzarelli, E., Spoto, G., Yeo, K.J., (2006) J. Mass Spectrom., 41, pp. 1561-1569
Haiss, W., Thanh, N.T.K., Aveyard, J., Fernig, D.G., (2007) Anal. Chem., 79, pp. 4215-4221
He, L., Musick, M.D., Nicewarner, S.R., Salinas, F.G., Benkovic, S.J., Natan, M.J., Keating, C.D., (2000) J. Am. Chem. Soc., 122, pp. 9071-9077
Ho, H.A., Doré, K., Boissinot, M., Bergeron, M.G., Tanguay, R.M., Boudreau, D., Leclerc, M., (2005) J. Am. Chem. Soc., 127, pp. 12673-12676
(2005), ISO 21569:, Foodstuffs - Methods of Analysis for the Detection of Genetically Modified Organisms and Derived Products - Qualitative Nucleic Acid Based Methods(2005), ISO 21570:, Foodstuffs - Methods of Analysis for the Detection of Genetically Modified Organisms and Derived Products - Quantitative Nucleic Acid Based MethodsLee, H.J., Wark, A.W., Corn, A.W., (2006) Langmuir, 22, pp. 5241-5250
Li-Qiang, C., Foerch, R., Knoll, W., (2007) Angew. Chem. Int. Ed., 46, pp. 4944-4947
Minunni, M., Tombelli, S., Mascini, M., (2007) Anal. Lett., 40, pp. 1360-1370
Perkel, J., (2008) Nat. Methods, 5, pp. 447-453
Rosi, N.L., Mirkin, C.A., (2005) Chem. Rev., 105, pp. 1547-1562
Rossi, S., Scaravelli, E., Germini, A., Corradini, R., Fogher, C., Marchelli, R., (2006) Eur. Food Res. Technol., 223, pp. 1-6
Rothenhäusler, B., Knoll, W., (1988) Nature, 332, pp. 615-617
Ruemmele, J.A., Golden, M.S., Gao, Y., Cornelius, E.M., Anderson, M.E., Postelnicu, L., Georgiadis, R.M., (2008) Anal. Chem., 80, pp. 4752-4756
Sassolas, A., Leca-Bouvier, B.D., Blum, L.J., (2008) Chem. Rev., 108, pp. 109-139
Scarano, S., Mascini, M., Turner, A.P.F., Minunni, M., (2009) Biosens. Bioelectron.
Shi, L., Perkins, R.G., Fang, H., Tong, W., (2008) Curr. Opin. Biotechnol., 19, pp. 10-18
Shultz, J.L., Kurunam, D., Shopinski, D., Iqbal, M.J., Kazi, S., Zobrist, K., Bashir, R., Lightfoot, D.A., (2006) Nucl. Acids Res., 34, pp. D758-D765
Sohni, Y., Kanjilal, S., Kapur, V., (2008) Clin. Biochem., 41, pp. 640-644
Stoeva, S.I., Lee, J., Thaxton, C.S., Mirkin, C.A., (2006) Angew. Chem. Int. Ed., 45, pp. 3303-3306
Storhoff, J.J., Lucas, A.D., Garimella, V., Bao, Y.P., Müller, U.R., (2004) Nat. Biotechnol., 22, pp. 883-887
Sujit, K.G., Tarasankar, P., (2007) Chem. Rev., 107, pp. 4797-4862
Totsingan, F., Rossi, S., Corradini, R., Tedeschi, T., Sforza, S., Juris, A., Scaravelli, E., Marchelli, R., (2008) Org. Biomol. Chem., 6, pp. 1232-1237
Wark, A.W., Lee, H.J., Corn, R.M., (2008) Angew. Chem. Int. Ed., 47, pp. 644-652
Yang, K., Moon, J.-K., Jeong, N., Back, K., Kim, H.M., Jeong, S.C., (2008) Genomics, 92, pp. 52-59
Zanoli, L., D'Agata, R., Spoto, G., (2008) Minerva Biotechnol., 20, pp. 165-174
Zhang, N., Appella, D.H., (2007) J. Am. Chem. Soc., 129, pp. 8424-8425
Zhao, W., Brook, M.A., Li, Y.F., (2008) ChemBioChem, 9, pp. 2363-2371
Zhu, D., Tang, Y., Xing, D., Chen, W.R., (2008) Anal. Chem., 80, pp. 3566-3571
Ultrasensitive detection of non-amplified genomic DNA by nanoparticle-enhanced surface plasmon resonance imaging
Technologies today available for the DNA detection rely on a combination of labeled probes hybridized to target sequences which are amplified by polymerase chain reaction (PCR). Direct detection methods that eliminate the requirement for both PCR and labeling steps could afford faster, cheaper and simpler devices for the analysis of small amounts of unamplified DNA. In this work we describe the results obtained in the ultrasensitive detection of non-amplified genomic DNA. We analyzed certified reference materials containing different amounts of genetically modified DNA by using a detection method which combines the nanoparticle-enhanced surface plasmon resonance imaging (SPRI) biosensing to the peptide nucleic acids (PNAs) improved selectivity and sensitivity in targeting complementary DNA sequences. The method allowed us to obtain a 41 zM sensitivity in targeting genomic DNA even in the presence of a large excess of non-complementary DNA. (C) 2010 Elsevier B.V. All rights reserved.
Technologies today available for the DNA detection rely on a combination of labeled probes hybridized to target sequences which are amplified by polymerase chain reaction (PCR). Direct detection methods that eliminate the requirement for both PCR and labeling steps could afford faster, cheaper and simpler devices for the analysis of small amounts of unamplified DNA. In this work we describe the results obtained in the ultrasensitive detection of non-amplified genomic DNA. We analyzed certified reference materials containing different amounts of genetically modified DNA by using a detection method which combines the nanoparticle-enhanced surface plasmon resonance imaging (SPRI) biosensing to the peptide nucleic acids (PNAs) improved selectivity and sensitivity in targeting complementary DNA sequences. The method allowed us to obtain a 41 zM sensitivity in targeting genomic DNA even in the presence of a large excess of non-complementary DNA. (C) 2010 Elsevier B.V. All rights reserved.
Ultrasensitive detection of non-amplified genomic DNA by nanoparticle-enhanced surface plasmon resonance imaging
| ▼ Structural characterization of proteins and enzymes isolated from organisms living under unusual conditions |
Ultrasensitive detection of non-amplified genomic DNA by nanoparticle-enhanced surface plasmon resonance imaging
Martinez-fernandez L, Banyasz A, Markovitsi D, Improta R
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* Selective sensing of Hg2+ by a proton-ionizable calix[4]arene fluoroionophore (292 visite)
Anal Bioanal Chem (ISSN: 1618-2642), 2013 Jan; 405(2-3): 1133-1137.
Impact Factor: 3.578
Dettagli Esporta in BibTeX Esporta in EndNote
D'Agata R, Spoto G
* Surface plasmon resonance imaging for nucleic acid detection (255 visite)
Anal Bioanal Chem (ISSN: 1618-2642), 2013 Jan; 405(2-3): 573-584.
Impact Factor: 3.578
Dettagli Esporta in BibTeX Esporta in EndNote
D'Agata R, Spoto G
* Artificial DNA and surface plasmon resonance (441 visite)
Artificial Dna Pna & Xna (ISSN: 1949-095x), 2012 Apr; 3(2): N/D-N/D.
Impact Factor: 0
Dettagli Esporta in BibTeX Esporta in EndNote
Zanoli LM, D'Agata R, Spoto G
* Functionalized gold nanoparticles for ultrasensitive DNA detection (217 visite)
Anal Bioanal Chem (ISSN: 1618-2642), 2012 Feb; 402(5): 1759-1771.
Impact Factor: 3.659
Dettagli Esporta in BibTeX Esporta in EndNote
Pilla P, Sandomenico A, Malachovsk V, Borriello A, Giordano M, Cutolo A, Ruvo M, Cusano A
* A protein-based biointerfacing route toward label-free immunoassays with long period gratings in transition mode (293 visite)
Biosens Bioelectron (ISSN: 0956-5663, 1873-4235electronic, 0956-5663linking), 2012 Jan 15; 31(1): 486-491.
Impact Factor: 5.437
Dettagli Esporta in BibTeX Esporta in EndNote
Magliulo M, Cella L, Pacelli R
* Novel technique radio frequency identification (RFID) based to manage patient flow in a radiotherapy department (217 visite)
Proc Ieee Embs Int Conf Biomed Health Informatics (ISSN: 9781-4577, 9781-457721779), 2012; N/D: 972-975.
Impact Factor: 0.41
Dettagli Esporta in BibTeX Esporta in EndNote
D'Agata R, Breveglieri G, Zanoli LM, Borgatti M, Spoto G, Gambari R
* Direct Detection of Point Mutations in Nonamplified Human Genomic DNA (597 visite)
Analytical Chemistry (ISSN: 0003-2700), 2011 Nov 15; 83(22): 8711-8717.
Impact Factor: 5.856
Dettagli Esporta in BibTeX Esporta in EndNote
Ruggiero A, Dattelbaum JD, Pennacchio A, Iozzino L, Staiano M, Luchansky MS, Der BS, Berisio R, D'Auria S, Vitagliano L
* Crystallization and preliminary X-ray crystallographic analysis of ligand-free and arginine-bound forms of Thermotoga maritima arginine-binding protein (283 visite)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2011 Nov 1; 67(11): 1462-1465.
Impact Factor: 0.506
Dettagli Esporta in BibTeX Esporta in EndNote
D'Agata R, Corradini R, Ferretti C, Zanoli L, Gatti M, Marchelli R, Spoto G
* Ultrasensitive detection of non-amplified genomic DNA (283 visite)
Lect Notes Electr Eng, 2010 May 15; 91LNEE: 485-488.
Impact Factor: 0
Dettagli Esporta in BibTeX Esporta in EndNote
D'Agata R, Corradini R, Ferretti C, Zanoli L, Gatti M, Marchelli R, Spoto G
* Detection Of Non Amplified Genomic Dna By Advanced Spri Methods (192 visite)
Chimica & L Industria, 2010; 7: 140-145.
Impact Factor: 0
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D'Antò V, Michelotti A, Esposito L, Zagari A, Liguori R, Sacchetti L
* Nonsynonimous mutation of catechol-O-methyl-transferase (COMT) gene in a patient with temporomandibular disorder (230 visite)
J Sci Med Sport (ISSN: 1440-2440), 2010; 13(6): 174-179.
Impact Factor: 3.194
Dettagli Esporta in BibTeX Esporta in EndNote
D'Agata R, Breveglieri G, Zanoli L, Borgatti M, Spoto G, Gambari R
* Surface Plasmon Resonance Imaging (SPR-I), peptide nucleic acid (PNA) probes and nanoparticle-enhancement for PCR-free ultrasensitive detection of beta-thalassemia mutations in human genomic DNA (219 visite)
International Journal Of Molecular Medicine (ISSN: 1107-3756), 2010; 26: N/D-N/D.
Impact Factor: 1.814
Dettagli Esporta in BibTeX Esporta in EndNote
Karunakaran V, Kleinermanns K, Improta R, Kovalenko SA
* Photoinduced dynamics of guanosine monophosphate in water from broad-band transient absorption spectroscopy and quantum-chemical calculations (233 visite)
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126), 2009; 131(16): 5839-5850.
Impact Factor: 8.58
Dettagli Esporta in BibTeX Esporta in EndNote
D'Agata R, Corradini R, Grasso G, Marchelli R, Spoto G
* Ultrasensitive detection of DNA by PNA and nanoparticle-enhanced surface plasmon resonance imaging (302 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2008 Sep 1; 9(13): 2067-2070.
Impact Factor: 3.322
Dettagli Esporta in BibTeX Esporta in EndNote
Zanoli L, Dagata R, Spoto G
* Surface plasmon-based optical detection of DNA peptide nucleic acids (203 visite)
Minerva Biotecnol (ISSN: 1120-4826), 2008; 20(4): 165-174.
Impact Factor: 0.1
Dettagli Esporta in BibTeX Esporta in EndNote
Staiano M, Saviano M, Herman P, Grycznyski Z, Fini C, Varriale A, Parracino A, Kold AB, Rossi M, D'Auria S
* Time-resolved fluorescence spectroscopy and molecular dynamics simulations point out the effects of pressure on the stability and dynamics of the porcine odorant-binding protein (433 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2008; 89(4): 284-291.
Impact Factor: 2.823
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Aloj L, Panico M, Caracó C, Zannetti A, Del Vecchio S, Di Nuzzo C, Arra C, Morelli G, Tesauro D, De Luca S, Pedone C, Salvatore M
* Radiolabeling approaches for cholecystokinin B receptor imaging (426 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2002; 66(6): 370-380.
Impact Factor: 2.372
Dettagli Esporta in BibTeX Esporta in EndNote
Vai a fine pagina Versione per copia e incolla facile Esporta tutto in BibTeX Esporta tutto in EndNote
Martinez-fernandez L, Banyasz A, Markovitsi D, Improta R
* Topology Controls the Electronic Absorption and Delocalization of Electron Holes in Guanine Quadruplexes (174 visite)
Chemistry (ISSN: 1521-3765electronic, 0947-6539linking), 2018 Oct 12; 24(57): 15185-15189.
Impact Factor: 5.476
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Smaldone G, Berisio R, Balasco N, D'Auria S, Vitagliano L, Ruggiero A
* Domain swapping dissection in Thermotoga maritima arginine binding protein: How structural flexibility may compensate destabilization (128 visite)
Bba-Gen Subjects (ISSN: 1570-9639print, 1570-9639linking, 0005-2728), 2018 May 31; 1866(9): 952-962.
Impact Factor: 2.773
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Avitabile C, Diaferia C, Della Ventura B, Mercurio FA, Leone M, Roviello V, Saviano M, Velotta R, Morelli G, Accardo A, Romanelli A
* Self-Assembling of Fmoc-GC Peptide Nucleic Acid Dimers into Highly Fluorescent Aggregates (287 visite)
Chemistry (ISSN: 1521-3765electronic, 0947-6539linking), 2018 Mar 26; 24(18): 4729-4735.
Impact Factor: 5.476
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Deiana M, Mettra B, Martinez-fernandez L, Mazur LM, Pawlik K, Andraud C, Samoc M, Improta R, Monnereau C, Matczyszyn K
* Specific Recognition of G-Quadruplexes Over Duplex-DNA by a Macromolecular NIR Two-Photon Fluorescent Probe (174 visite)
J Phys Chem Lett (ISSN: 1948-7185, 1948-7185electronic, 1948-7185linking), 2017 Dec 7; 8(23): 5915-5920.
Impact Factor: 8.709
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Maglio O, Costanzo S, Cercola R, Zambrano G, Mauro M, Battaglia R, Ferrini G, Nastri F, Pavone V, Lombardi A
* A Quartz Crystal Microbalance Immunosensor for Stem Cell Selection and Extraction (228 visite) (PDF 129 visite)
Sensors (ISSN: 1424-8220, 1424-3210, 1424-8220linking), 2017 Nov 28; 17(12): N/D-N/D.
Impact Factor: 2.475
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Platella C, Riccardi C, Montesarchio D, Roviello GN, Musumeci D
* G-quadruplex-based aptamers against protein targets in therapy and diagnostics (201 visite)
Bba-Gen Subjects (ISSN: 0304-4165, 0006-3002, 1872-8006electronic), 2017 May; 1861(5PtB): 1429-1447.
Impact Factor: 3.679
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Pepino AJ, Segarra-marti J, Nenov A, Improta R, Garavelli M
* Resolving Ultrafast Photoinduced Deactivations in Water-Solvated Pyrimidine Nucleosides (192 visite)
J Phys Chem Lett (ISSN: 1948-7185, 1948-7185electronic, 1948-7185linking), 2017 Apr 20; 8(8): 1777-1783.
Impact Factor: 8.709
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De Rosa L, Romanelli A, D'Andrea LD
* Chemical ligation in Structural Biology in “Chemical Ligation: Tools for Biomolecules Synthesis and Modification” (205 visite)
John Wiley & Sons, 2017; N/D: N/D-N/D.
Impact Factor: 0
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De Rosa L, Romanelli A, D'Andrea LD
* Introduction to chemical ligation reactions in Chemical Ligation: Tools for Biomolecules Synthesis and Modification (201 visite)
John Wiley & Sons, 2017; N/D: N/D-N/D.
Impact Factor: 0
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Giaquinto M, Micco A, Aliberti A, Ricciardi A, Ruvo M, Cutolo A, Cusano A
* Microgel photonics and lab on fiber technology for advanced label-free fiber optic nanoprobes (133 visite)
Proc Spie Int Soc Opt Eng (ISSN: 0277-786x9781510602199), 2016; 9916: N/D-N/D.
Impact Factor: 0.958
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Palladino P, Aura AM, Spoto G
* Surface plasmon resonance for the label-free detection of Alzheimer's β-amyloid peptide aggregation (387 visite)
Anal Bioanal Chem (ISSN: 1618-2642), 2016; 408(3): 849-854.
Impact Factor: 3.431
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Fahleson T, Kauczor J, Norman P, Santoro F, Improta R, Coriani S
* TD-DFT investigation of the magnetic circular dichroism spectra of some purine and pyrimidine bases of nucleic acids (250 visite)
J Phys Chem A (ISSN: 1089-5639, 1520-5215electronic), 2015; 119(21): 5476-5489.
Impact Factor: 2.883
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Changenet-Barret P, Gustavsson T, Improta R, Markovitsi D
* Ultrafast Excited-State Deactivation of 8-Hydroxy-2′-deoxyguanosine Studied by Femtosecond Fluorescence Spectroscopy and Quantum-Chemical Calculations (257 visite)
J Phys Chem A (ISSN: 1089-5639, 1520-5215electronic), 2015; 119(23): 6131-6139.
Impact Factor: 2.883
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Esposito L, Banyasz A, Douki T, Perron M, Markovitsi D, Improta R
* Effect of C5-methylation of cytosine on the photoreactivity of DNA: A joint experimental and computational study of TCG trinucleotides (229 visite)
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 0002-7863print), 2014 Sep 6; 136(31): 10838-10841.
Impact Factor: 12.113
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Olgiati S, De Rosa A, Quadri M, Criscuolo C, Breedveld GJ, Picillo M, Pappata S, Quarantelli M, Barone P, De Michele G, Bonifati V
* Park20 Caused By Synj1 Homozygous Arg258gln Mutation In A New Italian Family (386 visite)
Neurogenetics (ISSN: 1364-6745, 1364-6753), 2014 Aug; 15(3): 183-188.
Impact Factor: 2.884
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Giaquinto M, Micco A, Aliberti A, Ricciardi A, Ruvo M, Cutolo A, Cusano A
* Lab on fiber biosensors integrated with microgels (160 visite)
Opt Infobase Conf Pap (ISSN: 9780-960038053), 2014; N/D: N/D-N/D.
Impact Factor: 0
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Pica A, Russo Krauss I, Merlino A, Nagatoishi S, Sugimoto N, Sica F
* Dissecting the contribution of thrombin exosite I in the recognition of thrombin binding aptamer (281 visite)
Febs Journal (ISSN: 1742-464x), 2013 Dec; 280(24): 6581-6588.
Impact Factor: 3.986
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Quadri M, Fang M, Picillo M, Olgiati S, Breedveld Gj Graafland J, Wu B, Xu F, Erro R, Amboni M, Pappata S, Quarantelli M, Annesi G, Quattrone A, Chien Hf Barbosa ER, International Parkinsonism Genetics Network Oostra Ba Barone P, Wang J, Bonifati V
* Mutation in the SYNJ1 gene associated with autosomal recessive, early-onset Parkinsonism (306 visite)
Hum Mutat (ISSN: 1059-7794, 1098-1004, 1098-1004electronic), 2013 Sep; 34(9): 1208-1215.
Impact Factor: 5.122
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Hunger K, Buschhaus L, Biemann L, Braun M, Kovalenko S, Improta R, Kleinermanns K
* UV-light-induced hydrogen transfer in guanosine-guanosine aggregates (348 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2013 Apr; 19(17): 5425-5431.
Impact Factor: 5.696
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Grasso G, Spoto G
* Plasmonics for the study of metal ion-protein interactions (275 visite)
Anal Bioanal Chem (ISSN: 1618-2642), 2013 Feb; 405(6): 1833-1843.
Impact Factor: 3.578
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Causa F, Della Moglie R, Iaccino E, Mimmi S, Marasco D, Scognamiglio PL, Battista E, Palmieri C, Cosenza C, Sanguigno L, Quinto I, Scala G, Netti PA
* Evolutionary screening and adsorption behavior of engineered M13 bacteriophage and derived dodecapeptide for selective decoration of gold interfaces (321 visite)
J Colloid Interface Sci (ISSN: 0021-9797, 1095-7103electronic, 0021-9797linking), 2013 Jan 1; 389(1): 220-229.
Impact Factor: 1.646
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Zanoli LM, Licciardello M, D'Agata R, Lantano C, Calabretta A, Corradini R, Marchelli R, Spoto G
* Peptide nucleic acid molecular beacons for the detection of PCR amplicons in droplet-based microfluidic devices (209 visite)
Anal Bioanal Chem (ISSN: 1618-2642), 2013 Jan; 405(2-3): 615-624.
Impact Factor: 3.578
Dettagli Esporta in BibTeX Esporta in EndNote
Arena G, Attanasio F, Zhang D, Yang Y, Bartsch RA, Sgarlata C
* Selective sensing of Hg2+ by a proton-ionizable calix[4]arene fluoroionophore (292 visite)
Anal Bioanal Chem (ISSN: 1618-2642), 2013 Jan; 405(2-3): 1133-1137.
Impact Factor: 3.578
Dettagli Esporta in BibTeX Esporta in EndNote
D'Agata R, Spoto G
* Surface plasmon resonance imaging for nucleic acid detection (255 visite)
Anal Bioanal Chem (ISSN: 1618-2642), 2013 Jan; 405(2-3): 573-584.
Impact Factor: 3.578
Dettagli Esporta in BibTeX Esporta in EndNote
D'Agata R, Spoto G
* Artificial DNA and surface plasmon resonance (441 visite)
Artificial Dna Pna & Xna (ISSN: 1949-095x), 2012 Apr; 3(2): N/D-N/D.
Impact Factor: 0
Dettagli Esporta in BibTeX Esporta in EndNote
Zanoli LM, D'Agata R, Spoto G
* Functionalized gold nanoparticles for ultrasensitive DNA detection (217 visite)
Anal Bioanal Chem (ISSN: 1618-2642), 2012 Feb; 402(5): 1759-1771.
Impact Factor: 3.659
Dettagli Esporta in BibTeX Esporta in EndNote
Pilla P, Sandomenico A, Malachovsk V, Borriello A, Giordano M, Cutolo A, Ruvo M, Cusano A
* A protein-based biointerfacing route toward label-free immunoassays with long period gratings in transition mode (293 visite)
Biosens Bioelectron (ISSN: 0956-5663, 1873-4235electronic, 0956-5663linking), 2012 Jan 15; 31(1): 486-491.
Impact Factor: 5.437
Dettagli Esporta in BibTeX Esporta in EndNote
Magliulo M, Cella L, Pacelli R
* Novel technique radio frequency identification (RFID) based to manage patient flow in a radiotherapy department (217 visite)
Proc Ieee Embs Int Conf Biomed Health Informatics (ISSN: 9781-4577, 9781-457721779), 2012; N/D: 972-975.
Impact Factor: 0.41
Dettagli Esporta in BibTeX Esporta in EndNote
D'Agata R, Breveglieri G, Zanoli LM, Borgatti M, Spoto G, Gambari R
* Direct Detection of Point Mutations in Nonamplified Human Genomic DNA (597 visite)
Analytical Chemistry (ISSN: 0003-2700), 2011 Nov 15; 83(22): 8711-8717.
Impact Factor: 5.856
Dettagli Esporta in BibTeX Esporta in EndNote
Ruggiero A, Dattelbaum JD, Pennacchio A, Iozzino L, Staiano M, Luchansky MS, Der BS, Berisio R, D'Auria S, Vitagliano L
* Crystallization and preliminary X-ray crystallographic analysis of ligand-free and arginine-bound forms of Thermotoga maritima arginine-binding protein (283 visite)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2011 Nov 1; 67(11): 1462-1465.
Impact Factor: 0.506
Dettagli Esporta in BibTeX Esporta in EndNote
D'Agata R, Corradini R, Ferretti C, Zanoli L, Gatti M, Marchelli R, Spoto G
* Ultrasensitive detection of non-amplified genomic DNA (283 visite)
Lect Notes Electr Eng, 2010 May 15; 91LNEE: 485-488.
Impact Factor: 0
Dettagli Esporta in BibTeX Esporta in EndNote
D'Agata R, Corradini R, Ferretti C, Zanoli L, Gatti M, Marchelli R, Spoto G
* Detection Of Non Amplified Genomic Dna By Advanced Spri Methods (192 visite)
Chimica & L Industria, 2010; 7: 140-145.
Impact Factor: 0
Dettagli Esporta in BibTeX Esporta in EndNote
D'Antò V, Michelotti A, Esposito L, Zagari A, Liguori R, Sacchetti L
* Nonsynonimous mutation of catechol-O-methyl-transferase (COMT) gene in a patient with temporomandibular disorder (230 visite)
J Sci Med Sport (ISSN: 1440-2440), 2010; 13(6): 174-179.
Impact Factor: 3.194
Dettagli Esporta in BibTeX Esporta in EndNote
D'Agata R, Breveglieri G, Zanoli L, Borgatti M, Spoto G, Gambari R
* Surface Plasmon Resonance Imaging (SPR-I), peptide nucleic acid (PNA) probes and nanoparticle-enhancement for PCR-free ultrasensitive detection of beta-thalassemia mutations in human genomic DNA (219 visite)
International Journal Of Molecular Medicine (ISSN: 1107-3756), 2010; 26: N/D-N/D.
Impact Factor: 1.814
Dettagli Esporta in BibTeX Esporta in EndNote
Karunakaran V, Kleinermanns K, Improta R, Kovalenko SA
* Photoinduced dynamics of guanosine monophosphate in water from broad-band transient absorption spectroscopy and quantum-chemical calculations (233 visite)
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126), 2009; 131(16): 5839-5850.
Impact Factor: 8.58
Dettagli Esporta in BibTeX Esporta in EndNote
D'Agata R, Corradini R, Grasso G, Marchelli R, Spoto G
* Ultrasensitive detection of DNA by PNA and nanoparticle-enhanced surface plasmon resonance imaging (302 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2008 Sep 1; 9(13): 2067-2070.
Impact Factor: 3.322
Dettagli Esporta in BibTeX Esporta in EndNote
Zanoli L, Dagata R, Spoto G
* Surface plasmon-based optical detection of DNA peptide nucleic acids (203 visite)
Minerva Biotecnol (ISSN: 1120-4826), 2008; 20(4): 165-174.
Impact Factor: 0.1
Dettagli Esporta in BibTeX Esporta in EndNote
Staiano M, Saviano M, Herman P, Grycznyski Z, Fini C, Varriale A, Parracino A, Kold AB, Rossi M, D'Auria S
* Time-resolved fluorescence spectroscopy and molecular dynamics simulations point out the effects of pressure on the stability and dynamics of the porcine odorant-binding protein (433 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2008; 89(4): 284-291.
Impact Factor: 2.823
Dettagli Esporta in BibTeX Esporta in EndNote
Aloj L, Panico M, Caracó C, Zannetti A, Del Vecchio S, Di Nuzzo C, Arra C, Morelli G, Tesauro D, De Luca S, Pedone C, Salvatore M
* Radiolabeling approaches for cholecystokinin B receptor imaging (426 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2002; 66(6): 370-380.
Impact Factor: 2.372
Dettagli Esporta in BibTeX Esporta in EndNote
39 Records (33 escludendo Abstract e Conferenze).
Impact factor totale: 131.284 (124.423 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 134.246 (126.305 escludendo Abstract e Conferenze).
Impact factor totale: 131.284 (124.423 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 134.246 (126.305 escludendo Abstract e Conferenze).
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