Ultrasensitive detection of non-amplified genomic DNA by nanoparticle-enhanced surface plasmon resonance imaging
CNR Ibb | back to homepage
▲NavBar
Ricerca avanzata▼
Contiene: [X]      Estesa     Autori: [X]  Tipo di lavoro: [X]   Data iniziale: Data finale: [X]      Sede: Affiliazione IBB     
    
[Pulisci modulo]


Ultrasensitive detection of non-amplified genomic DNA by nanoparticle-enhanced surface plasmon resonance imaging (126 visite)

D'Agata R, Corradini R, Ferretti C, Zanoli L, Gatti M, Marchelli R, Spoto G

Biosens Bioelectron (ISSN: 0956-5663, 1873-4235electronic), 2010 May 15; 25(9): 2095-2100.



Tipo di articolo: Journal Article,

Impact factor: 5.361, Impact factor a 5 anni: 5.397

Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-77951622977&partnerID=40&md5=0197784a9f4f3c1c0364eb8176933242

Parole chiave: Biosensors, Dna Sensing, Genomic Dna, Pcr-Free, Peptide Nucleic Acids, Surface-Plasmon Resonance, Biosensing, Certified Reference Materials, Detection Methods, Direct Detection, Dna Detection, Enhanced Surface, Genetically Modified, Labeling Steps, Selectivity And Sensitivity, Target Sequences, Ultrasensitive Detection, Biomolecules, Dna Sequences, Nanoparticles, Polymerase Chain Reaction, Surface Plasmon Resonance, Complementary Dna, Analytic Method, Controlled Study, Dna Determination, Gene Amplification, Gene Targeting, Image Enhancement, Sensitivity Analysis, Base Sequence, Recombinant, Gold, Metal Nanoparticles, Plants, Soybeans,

Affiliazioni:

*** IBB - CNR ***
Dipartimento di Scienze Chimiche, Università di Catania, Viale Andrea Doria 6, I-95125 Catania, Italy
Dipartimento di Chimica Organica ed Industriale, Università di Parma, Viale G.P. Usberti 17/a, I-43100 Parma, Italy
Neotron S.p.a., Stradello Aggazzotti 104, I-41010 Modena, Italy
Scuola Superiore di Catania, C/o Dipartimento di Scienze Chimiche, Università di Catania, Viale Andrea Doria 6, Catania, Italy
Istituto Biostrutture e Bioimmagini, CNR, Viale A. Doria 6, Catania, Italy


Riferimenti:

Arena, G., Contino, A., Longo, E., Sgarlata, C., Spoto, G., Zito, V., (2004) Chem. Commun., 16, pp. 1812-181

Berdal, K.G., Bøydler, C., Tengs, T., Holst-Jensen, A., (2008) Eur. Food Res. Technol., 227, pp. 1149-1157

Burns, C., Spendel, W.U., Puckett, S., Pacey, G.E., (2006) Talanta, 69, pp. 873-876

D'Agata, R., Corradini, R., Grasso, G., Marchelli, R., Spoto, G., (2008) ChemBioChem, 9, pp. 2067-2070

D'Agata, R., Grasso, G., Iacono, G., Spoto, G., Vecchio, G., (2006) Org. Biomol. Chem., 4, pp. 610-612

Dos Santos Riccardi, C., Kranz, C., Kowalik, J., Yamanaka, H., Mizaikoff, B., Josowicz, M., (2008) Anal. Chem., 80, pp. 237-245

Germini, A., Rossi, S., Zanetti, A., Corradini, R., Fogher, C., Marchelli, R., (2005) J. Agric. Food Chem., 53, pp. 3958-3962

Gibson, G., (2008) Nat. Rev. Genet., 9, pp. 575-581

(2009), http://ec.europa.eu/food/dyna/gm_register/index_en.cfm, GM Food & Feed, Community Register of GM Food and Feed, Event MON 40-3-2. (accessed 20.11.09)Goodrich, T.T., Lee, H.J., Corn, R.M., (2004) J. Am. Chem. Soc., 126, pp. 4086-4087

Grabar, K.C., Freeman, R.G., Hommer, M.B., Natan, M.J., (1995) Anal. Chem., 67, pp. 735-743

Grasso, G., Bush, A.I., D'Agata, R., Rizzarelli, E., Spoto, G., (2009) Eur. Biophys. J., Biophys. Lett., 38, pp. 407-414

Grasso, G., D'Agata, R., Zanoli, L., Spoto, G., (2009) Microchem. J., 93, pp. 82-86

Grasso, G., Fragai, M., Rizzarelli, E., Spoto, G., Yeo, K.J., (2006) J. Mass Spectrom., 41, pp. 1561-1569

Haiss, W., Thanh, N.T.K., Aveyard, J., Fernig, D.G., (2007) Anal. Chem., 79, pp. 4215-4221

He, L., Musick, M.D., Nicewarner, S.R., Salinas, F.G., Benkovic, S.J., Natan, M.J., Keating, C.D., (2000) J. Am. Chem. Soc., 122, pp. 9071-9077

Ho, H.A., Doré, K., Boissinot, M., Bergeron, M.G., Tanguay, R.M., Boudreau, D., Leclerc, M., (2005) J. Am. Chem. Soc., 127, pp. 12673-12676

(2005), ISO 21569:, Foodstuffs - Methods of Analysis for the Detection of Genetically Modified Organisms and Derived Products - Qualitative Nucleic Acid Based Methods(2005), ISO 21570:, Foodstuffs - Methods of Analysis for the Detection of Genetically Modified Organisms and Derived Products - Quantitative Nucleic Acid Based MethodsLee, H.J., Wark, A.W., Corn, A.W., (2006) Langmuir, 22, pp. 5241-5250

Li-Qiang, C., Foerch, R., Knoll, W., (2007) Angew. Chem. Int. Ed., 46, pp. 4944-4947

Minunni, M., Tombelli, S., Mascini, M., (2007) Anal. Lett., 40, pp. 1360-1370

Perkel, J., (2008) Nat. Methods, 5, pp. 447-453

Rosi, N.L., Mirkin, C.A., (2005) Chem. Rev., 105, pp. 1547-1562

Rossi, S., Scaravelli, E., Germini, A., Corradini, R., Fogher, C., Marchelli, R., (2006) Eur. Food Res. Technol., 223, pp. 1-6

Rothenhäusler, B., Knoll, W., (1988) Nature, 332, pp. 615-617

Ruemmele, J.A., Golden, M.S., Gao, Y., Cornelius, E.M., Anderson, M.E., Postelnicu, L., Georgiadis, R.M., (2008) Anal. Chem., 80, pp. 4752-4756

Sassolas, A., Leca-Bouvier, B.D., Blum, L.J., (2008) Chem. Rev., 108, pp. 109-139

Scarano, S., Mascini, M., Turner, A.P.F., Minunni, M., (2009) Biosens. Bioelectron.

Shi, L., Perkins, R.G., Fang, H., Tong, W., (2008) Curr. Opin. Biotechnol., 19, pp. 10-18

Shultz, J.L., Kurunam, D., Shopinski, D., Iqbal, M.J., Kazi, S., Zobrist, K., Bashir, R., Lightfoot, D.A., (2006) Nucl. Acids Res., 34, pp. D758-D765

Sohni, Y., Kanjilal, S., Kapur, V., (2008) Clin. Biochem., 41, pp. 640-644

Stoeva, S.I., Lee, J., Thaxton, C.S., Mirkin, C.A., (2006) Angew. Chem. Int. Ed., 45, pp. 3303-3306

Storhoff, J.J., Lucas, A.D., Garimella, V., Bao, Y.P., Müller, U.R., (2004) Nat. Biotechnol., 22, pp. 883-887

Sujit, K.G., Tarasankar, P., (2007) Chem. Rev., 107, pp. 4797-4862

Totsingan, F., Rossi, S., Corradini, R., Tedeschi, T., Sforza, S., Juris, A., Scaravelli, E., Marchelli, R., (2008) Org. Biomol. Chem., 6, pp. 1232-1237

Wark, A.W., Lee, H.J., Corn, R.M., (2008) Angew. Chem. Int. Ed., 47, pp. 644-652

Yang, K., Moon, J.-K., Jeong, N., Back, K., Kim, H.M., Jeong, S.C., (2008) Genomics, 92, pp. 52-59

Zanoli, L., D'Agata, R., Spoto, G., (2008) Minerva Biotechnol., 20, pp. 165-174

Zhang, N., Appella, D.H., (2007) J. Am. Chem. Soc., 129, pp. 8424-8425

Zhao, W., Brook, M.A., Li, Y.F., (2008) ChemBioChem, 9, pp. 2363-2371

Zhu, D., Tang, Y., Xing, D., Chen, W.R., (2008) Anal. Chem., 80, pp. 3566-3571



Technologies today available for the DNA detection rely on a combination of labeled probes hybridized to target sequences which are amplified by polymerase chain reaction (PCR). Direct detection methods that eliminate the requirement for both PCR and labeling steps could afford faster, cheaper and simpler devices for the analysis of small amounts of unamplified DNA. In this work we describe the results obtained in the ultrasensitive detection of non-amplified genomic DNA. We analyzed certified reference materials containing different amounts of genetically modified DNA by using a detection method which combines the nanoparticle-enhanced surface plasmon resonance imaging (SPRI) biosensing to the peptide nucleic acids (PNAs) improved selectivity and sensitivity in targeting complementary DNA sequences. The method allowed us to obtain a 41 zM sensitivity in targeting genomic DNA even in the presence of a large excess of non-complementary DNA. (C) 2010 Elsevier B.V. All rights reserved.
Nessun risultato.

Ricerca avanzata▼
Contiene: [X]      Estesa     Autori: [X]  Tipo di lavoro: [X]   Data iniziale: Data finale: [X]      Sede: Affiliazione IBB     
    
[Pulisci modulo]
Vai a fine pagina   Versione per copia e incolla facile   Esporta tutto in BibTeX   Esporta tutto in EndNote


Smaldone G, Berisio R, Balasco N, D'Auria S, Vitagliano L, Ruggiero A
* Domain swapping dissection in Thermotoga maritima arginine binding protein: How structural flexibility may compensate destabilization (51 visite)
Biochim Biophys Acta Proteins Proteom (ISSN: 1570-9639print, 1570-9639linking), 2018 May 31; 1866(9): 952-962.
Impact Factor: 2.773
Dettagli    Esporta in BibTeX    Esporta in EndNote

Avitabile C, Diaferia C, Della Ventura B, Mercurio FA, Leone M, Roviello V, Saviano M, Velotta R, Morelli G, Accardo A, Romanelli A
* Self-Assembling of Fmoc-GC Peptide Nucleic Acid Dimers into Highly Fluorescent Aggregates (124 visite)
Chemistry (ISSN: 1521-3765electronic, 0947-6539linking), 2018 Mar 26; 24(18): 4729-4735.
Impact Factor: 5.476
Dettagli    Esporta in BibTeX    Esporta in EndNote

Maglio O, Costanzo S, Cercola R, Zambrano G, Mauro M, Battaglia R, Ferrini G, Nastri F, Pavone V, Lombardi A
* A Quartz Crystal Microbalance Immunosensor for Stem Cell Selection and Extraction (96 visite) (PDF 60 visite)
Sensors (ISSN: 1424-8220, 1424-3210, 1424-8220linking), 2017 Nov 28; 17(12): N/D-N/D.
Impact Factor: 2.475
Dettagli    Esporta in BibTeX    Esporta in EndNote

Piras L, Avitabile C, D'Andrea LD, Saviano M, Romanelli A
* Detection of oligonucleotides by PNA-peptide conjugates recognizing the biarsenical fluorescein complex FlAsH-EDT2 (95 visite)
Biochem Bioph Res Co (ISSN: 0006-291x), 2017 Sep 15; N/D: N/D-N/D.
Impact Factor: 2.559
Dettagli    Esporta in BibTeX    Esporta in EndNote

Platella C, Riccardi C, Montesarchio D, Roviello GN, Musumeci D
* G-quadruplex-based aptamers against protein targets in therapy and diagnostics (97 visite)
Bba-Gen Subjects (ISSN: 0304-4165, 0006-3002, 1872-8006electronic), 2017 May; 1861(5PtB): 1429-1447.
Impact Factor: 3.679
Dettagli    Esporta in BibTeX    Esporta in EndNote

Giaquinto M, Micco A, Aliberti A, Ricciardi A, Ruvo M, Cutolo A, Cusano A
* Microgel photonics and lab on fiber technology for advanced label-free fiber optic nanoprobes (17 visite)
Proc Spie Int Soc Opt Eng (ISSN: 0277-786x9781510602199), 2016; 9916: N/D-N/D.
Impact Factor: 0.958
Dettagli    Esporta in BibTeX    Esporta in EndNote

Palladino P, Aura AM, Spoto G
* Surface plasmon resonance for the label-free detection of Alzheimer's β-amyloid peptide aggregation (204 visite)
Anal Bioanal Chem (ISSN: 1618-2642), 2016; 408(3): 849-854.
Impact Factor: 3.431
Dettagli    Esporta in BibTeX    Esporta in EndNote

Avitabile C, Accardo A, Ringhieri P, Morelli G, Saviano M, Montagner G, Fabbri E, Gallerani E, Gambari R, Romanelli A
* Incorporation of Naked Peptide Nucleic Acids into Liposomes Leads to Fast and Efficient Delivery (126 visite)
Bioconjug Chem (ISSN: 1043-1802, 1520-4812), 2015; 26(8): 1533-1541.
Impact Factor: 4.5
Dettagli    Esporta in BibTeX    Esporta in EndNote

Olgiati S, De Rosa A, Quadri M, Criscuolo C, Breedveld GJ, Picillo M, Pappata S, Quarantelli M, Barone P, De Michele G, Bonifati V
* Park20 Caused By Synj1 Homozygous Arg258gln Mutation In A New Italian Family (154 visite)
Neurogenetics (ISSN: 1364-6745, 1364-6753), 2014 Aug; 15(3): 183-188.
Impact Factor: 2.884
Dettagli    Esporta in BibTeX    Esporta in EndNote

Giaquinto M, Micco A, Aliberti A, Ricciardi A, Ruvo M, Cutolo A, Cusano A
* Lab on fiber biosensors integrated with microgels (24 visite)
Opt Infobase Conf Pap (ISSN: 9780-960038053), 2014; N/D: N/D-N/D.
Impact Factor: 0
Dettagli    Esporta in BibTeX    Esporta in EndNote

Pica A, Russo Krauss I, Merlino A, Nagatoishi S, Sugimoto N, Sica F
* Dissecting the contribution of thrombin exosite I in the recognition of thrombin binding aptamer (176 visite)
Febs Journal (ISSN: 1742-464x), 2013 Dec; 280(24): 6581-6588.
Impact Factor: 3.986
Dettagli    Esporta in BibTeX    Esporta in EndNote

Quadri M, Fang M, Picillo M, Olgiati S, Breedveld Gj Graafland J, Wu B, Xu F, Erro R, Amboni M, Pappata S, Quarantelli M, Annesi G, Quattrone A, Chien Hf Barbosa ER, International Parkinsonism Genetics Network Oostra Ba Barone P, Wang J, Bonifati V
* Mutation in the SYNJ1 gene associated with autosomal recessive, early-onset Parkinsonism (158 visite)
Hum Mutat (ISSN: 1059-7794, 1098-1004, 1098-1004electronic), 2013 Sep; 34(9): 1208-1215.
Impact Factor: 5.122
Dettagli    Esporta in BibTeX    Esporta in EndNote

Grasso G, Spoto G
* Plasmonics for the study of metal ion-protein interactions (161 visite)
Anal Bioanal Chem (ISSN: 1618-2642), 2013 Feb; 405(6): 1833-1843.
Impact Factor: 3.578
Dettagli    Esporta in BibTeX    Esporta in EndNote

Zanoli LM, Licciardello M, D'Agata R, Lantano C, Calabretta A, Corradini R, Marchelli R, Spoto G
* Peptide nucleic acid molecular beacons for the detection of PCR amplicons in droplet-based microfluidic devices (107 visite)
Anal Bioanal Chem (ISSN: 1618-2642), 2013 Jan; 405(2-3): 615-624.
Impact Factor: 3.578
Dettagli    Esporta in BibTeX    Esporta in EndNote

Arena G, Attanasio F, Zhang D, Yang Y, Bartsch RA, Sgarlata C
* Selective sensing of Hg2+ by a proton-ionizable calix[4]arene fluoroionophore (170 visite)
Anal Bioanal Chem (ISSN: 1618-2642), 2013 Jan; 405(2-3): 1133-1137.
Impact Factor: 3.578
Dettagli    Esporta in BibTeX    Esporta in EndNote

D'Agata R, Spoto G
* Surface plasmon resonance imaging for nucleic acid detection (153 visite)
Anal Bioanal Chem (ISSN: 1618-2642), 2013 Jan; 405(2-3): 573-584.
Impact Factor: 3.578
Dettagli    Esporta in BibTeX    Esporta in EndNote

Roviello GN, Musumeci D, Bucci EM, Pedone C
* Synthesis of a diaminopropanoic acid-based nucleoamino acid and assembly of cationic nucleopeptides for biomedical applications (180 visite)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2012 Dec; 43(6): 2537-2543.
Impact Factor: 3.914
Dettagli    Esporta in BibTeX    Esporta in EndNote

Roviello GN, Roviello G, Musumeci D, Bucci EM, Pedone C
* Dakin-West reaction on 1-thyminyl acetic acid for the synthesis of 1, 3-bis(1-thyminyl)-2-propanone, a heteroaromatic compound with nucleopeptide-binding properties (142 visite)
Amino Acids (ISSN: 1438-2199, 0939-4451, 1438-2199electronic), 2012 Oct; 43(4): 1615-1623.
Impact Factor: 3.914
Dettagli    Esporta in BibTeX    Esporta in EndNote

D'Agata R, Spoto G
* Artificial DNA and surface plasmon resonance (210 visite)
Artificial Dna Pna & Xna (ISSN: 1949-095x), 2012 Apr; 3(2): N/D-N/D.
Impact Factor: 0
Dettagli    Esporta in BibTeX    Esporta in EndNote

Avitabile C, Saviano M, D'Andrea LD, Bianchi N, Fabbri E, Brognara E, Gambari R, Romanelli A
* Targeting pre-miRNA by peptide nucleic acids: a new strategy to interfere in the miRNA maturation (181 visite)
Artif Dna Pna Xnaartificial Dna Pna & Xna (ISSN: 1949-9096, 1949-0968, 1949-095x), 2012 Apr; 3(2): 88-96.
Impact Factor: 0
Dettagli    Esporta in BibTeX    Esporta in EndNote

Zanoli LM, D'Agata R, Spoto G
* Functionalized gold nanoparticles for ultrasensitive DNA detection (110 visite)
Anal Bioanal Chem (ISSN: 1618-2642), 2012 Feb; 402(5): 1759-1771.
Impact Factor: 3.659
Dettagli    Esporta in BibTeX    Esporta in EndNote

Pilla P, Sandomenico A, Malachovsk V, Borriello A, Giordano M, Cutolo A, Ruvo M, Cusano A
* A protein-based biointerfacing route toward label-free immunoassays with long period gratings in transition mode (154 visite)
Biosens Bioelectron (ISSN: 0956-5663, 1873-4235electronic, 0956-5663linking), 2012 Jan 15; 31(1): 486-491.
Impact Factor: 5.437
Dettagli    Esporta in BibTeX    Esporta in EndNote

Magliulo M, Cella L, Pacelli R
* Novel technique radio frequency identification (RFID) based to manage patient flow in a radiotherapy department (110 visite)
Proc Ieee Embs Int Conf Biomed Health Informatics (ISSN: 9781-4577, 9781-457721779), 2012; N/D: 972-975.
Impact Factor: 0.41
Dettagli    Esporta in BibTeX    Esporta in EndNote

D'Agata R, Breveglieri G, Zanoli LM, Borgatti M, Spoto G, Gambari R
* Direct Detection of Point Mutations in Nonamplified Human Genomic DNA (467 visite)
Analytical Chemistry (ISSN: 0003-2700), 2011 Nov 15; 83(22): 8711-8717.
Impact Factor: 5.856
Dettagli    Esporta in BibTeX    Esporta in EndNote

Ruggiero A, Dattelbaum JD, Pennacchio A, Iozzino L, Staiano M, Luchansky MS, Der BS, Berisio R, D'Auria S, Vitagliano L
* Crystallization and preliminary X-ray crystallographic analysis of ligand-free and arginine-bound forms of Thermotoga maritima arginine-binding protein (161 visite)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2011 Nov 1; 67(11): 1462-1465.
Impact Factor: 0.506
Dettagli    Esporta in BibTeX    Esporta in EndNote

Roviello GN, Musumeci D, Bucci EM, Pedone C
* Synthesis and characterization of a novel ester-based nucleoamino acid for the assembly of aromatic nucleopeptides for biomedical applications (234 visite)
Int J Pharm (ISSN: 0378-5173, 1873-3476), 2011 Sep 30; 415(1-2): 206-210.
Impact Factor: 3.35
Dettagli    Esporta in BibTeX    Esporta in EndNote

Roviello GN, Crescenzo C, Capasso D, Di Gaetano S, Franco S, Bucci EM, Pedone C
* Synthesis of a novel Fmoc-protected nucleoaminoacid for the solid phase assembly of 4-piperidyl glycine/L-arginine-containing nucleopeptides and preliminary RNA interaction studies (179 visite)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010 Sep; 39(3): 795-800.
Impact Factor: 4.106
Dettagli    Esporta in BibTeX    Esporta in EndNote

D'Agata R, Corradini R, Ferretti C, Zanoli L, Gatti M, Marchelli R, Spoto G
* Ultrasensitive detection of non-amplified genomic DNA (195 visite)
Lect Notes Electr Eng, 2010 May 15; 91LNEE: 485-488.
Impact Factor: 0
Dettagli    Esporta in BibTeX    Esporta in EndNote

D'Agata R, Corradini R, Ferretti C, Zanoli L, Gatti M, Marchelli R, Spoto G
* Detection Of Non Amplified Genomic Dna By Advanced Spri Methods (114 visite)
Chimica & L Industria, 2010; 7: 140-145.
Impact Factor: 0
Dettagli    Esporta in BibTeX    Esporta in EndNote

D'Antò V, Michelotti A, Esposito L, Zagari A, Liguori R, Sacchetti L
* Nonsynonimous mutation of catechol-O-methyl-transferase (COMT) gene in a patient with temporomandibular disorder (156 visite)
J Sci Med Sport (ISSN: 1440-2440), 2010; 13(6): 174-179.
Impact Factor: 3.194
Dettagli    Esporta in BibTeX    Esporta in EndNote

D'Agata R, Breveglieri G, Zanoli L, Borgatti M, Spoto G, Gambari R
* Surface Plasmon Resonance Imaging (SPR-I), peptide nucleic acid (PNA) probes and nanoparticle-enhancement for PCR-free ultrasensitive detection of beta-thalassemia mutations in human genomic DNA (122 visite)
International Journal Of Molecular Medicine (ISSN: 1107-3756), 2010; 26: N/D-N/D.
Impact Factor: 1.814
Dettagli    Esporta in BibTeX    Esporta in EndNote

Roviello GN, Musumeci D, Bucci EM, Castiglione M, Cesarani A, Pedone C, Piccialli G
* Evidences for complex formation between l-dabPNA and aegPNA (117 visite)
Bioorg Med Chem Lett (ISSN: 0960-894x, 1464-3405, 1464-3405electronic), 2008 Sep 1; 18(17): 4757-4760.
Impact Factor: 2.531
Dettagli    Esporta in BibTeX    Esporta in EndNote

D'Agata R, Corradini R, Grasso G, Marchelli R, Spoto G
* Ultrasensitive detection of DNA by PNA and nanoparticle-enhanced surface plasmon resonance imaging (183 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2008 Sep 1; 9(13): 2067-2070.
Impact Factor: 3.322
Dettagli    Esporta in BibTeX    Esporta in EndNote

Breveglieri G, Pensato S, Salvatori F, Saviano M, Pedone C, Romanelli A, Gambari R
* PNA-mediated alteration of mRNA splicing (121 visite)
Minerva Biotecnol (ISSN: 1120-4826), 2008; 20(4): 175-181.
Impact Factor: 0.1
Dettagli    Esporta in BibTeX    Esporta in EndNote

Marchelli R, Saviano M, Licandro E, Spoto G, Borgatti M, Gambari R
* PNAs targeting the "RNA world": Micro RNA next? (137 visite)
Minerva Biotecnol (ISSN: 1120-4826), 2008; 20(4): 183-188.
Impact Factor: 0.1
Dettagli    Esporta in BibTeX    Esporta in EndNote

Zanoli L, Dagata R, Spoto G
* Surface plasmon-based optical detection of DNA peptide nucleic acids (133 visite)
Minerva Biotecnol (ISSN: 1120-4826), 2008; 20(4): 165-174.
Impact Factor: 0.1
Dettagli    Esporta in BibTeX    Esporta in EndNote

Staiano M, Saviano M, Herman P, Grycznyski Z, Fini C, Varriale A, Parracino A, Kold AB, Rossi M, D'Auria S
* Time-resolved fluorescence spectroscopy and molecular dynamics simulations point out the effects of pressure on the stability and dynamics of the porcine odorant-binding protein (211 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2008; 89(4): 284-291.
Impact Factor: 2.823
Dettagli    Esporta in BibTeX    Esporta in EndNote

Moccia M, Musumeci D, Valente M, Roviello GN, Sapio R, Pedone C, Bucci EM
* Thermodynamic studies on PNA and PNA/DNA dendrimer formation (91 visite)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1525-7770), 2007; 26(8-9): 1173-1176.
Impact Factor: 0.723
Dettagli    Esporta in BibTeX    Esporta in EndNote

Roviello GN, Moccia M, Sapio R, Valente M, Bucci EM, Castiglione M, Pedone C, Perretta G, Benedetti E, Musumeci D
* Synthesis, Characterization And Hybridization Studies Of New Nucleo-Gamma-Peptides Based On Diaminobutyric Acid (176 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2006 Dec; 12(12): 829-835.
Impact Factor: 1.801
Dettagli    Esporta in BibTeX    Esporta in EndNote

Borgatti M, Boyd DD, Lampronti I, Bianchi N, Fabbri E, Saviano M, Romanelli A, Pedone C, Gambari R
* Decoy molecules based on PNA-DNA chimeras and targeting Sp1 transcription factors inhibit the activity of urokinase-type plasminogen activator receptor (uPAR) promoter (155 visite)
Oncology Research (ISSN: 0965-0407), 2005; 15(7-8): 373-383.
Impact Factor: 1.844
Dettagli    Esporta in BibTeX    Esporta in EndNote

Borgatti M, Finotti A, Romanelli A, Saviano M, Bianchi N, Lampronti I, Lambertini E, Penolazzi L, Nastruzzi C, Mischiati C, Piva R, Pedone C, Gambari R
* Peptide nucleic acids (PNA)-DNA chimeras targeting transcription factors as a tool to modify gene expression (142 visite)
Curr Drug Targets (ISSN: 1389-4501), 2004 Nov; 5(8): 735-744.
Impact Factor: 4.104
Dettagli    Esporta in BibTeX    Esporta in EndNote

Cortesi R, Mischiati C, Borgatti M, Breda L, Romanelli A, Saviano M, Pedone C, Gambari R, Nastruzzi C
* Formulations for natural and peptide nucleic acids based on cationic polymeric submicron particles (140 visite)
The Aaps Journal (ISSN: 1522-1059, 1550-7416), 2004 Jan 20; 6(1): N/D-N/D.
Impact Factor: 1.938
Dettagli    Esporta in BibTeX    Esporta in EndNote

Musumeci D, Roviello  GN, Valente M, Sapio R, Pedone C, Bucci EM
* New synthesis of PNA-3′DNA linker monomers, useful building blocks to obtain PNA/DNA chimeras (141 visite)
Biopolymers, 2004; 76(6): 535-542.
Impact Factor: 2.248
Dettagli    Esporta in BibTeX    Esporta in EndNote

Gambari R, Borgatti M, Romanelli A, Capasso D, Saviano M, Bianchi N, Lampronti I, Mischiati C, Pedone C
* Transcription factor decoy (TFD) activity of peptide nucleic acids (PNA)-DNA chimeras (118 visite)
International Journal Of Molecular Medicine (ISSN: 1107-3756), 2003; 12(Supplement1): N/D-N/D.
Impact Factor: 1.94
Dettagli    Esporta in BibTeX    Esporta in EndNote

Romanelli A, Pedone C, Saviano M, Bianchi N, Borgatti M, Mischiati C, Gambari R
* Molecular interactions between nuclear factor κB (NF-κB) transcription factors and a PNA-DNA chimera mimicking NF-κB binding sites (133 visite)
Eur J Biochem (ISSN: 0014-2956, 0014-2956print, 0014-2956linking), 2001 Dec; 268(23): 6066-6075.
Impact Factor: 2.849
Dettagli    Esporta in BibTeX    Esporta in EndNote

Romanelli A, Pedone C, Saviano M, Bianchi N, Borgatti M, Mischiati C, Gambari R
* Molecular interactions with nuclear factor kappaB (NF-kappaB) transcription factors of a PNA-DNA chimera mimicking NF-kappaB binding sites (108 visite)
Eur J Biochem (ISSN: 0014-2956print, 0014-2956linking), 2001 Dec; 268(23): 6066-6075.
Impact Factor: 4.779
Dettagli    Esporta in BibTeX    Esporta in EndNote



46 Records (38 escludendo Abstract e Conferenze).
Impact factor totale: 119.517 (108.778 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 123.724 (108.911 escludendo Abstract e Conferenze).







    Esporta in BibTeX    Esporta in EndNote