Ultrasensitive detection of non-amplified genomic DNA by nanoparticle-enhanced surface plasmon resonance imaging (191 visite)
Biosens Bioelectron (ISSN: 0956-5663, 1873-4235electronic), 2010 May 15; 25(9): 2095-2100.
Tipo di articolo: Journal Article,
Impact factor: 5.361, Impact factor a 5 anni: 5.397
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-77951622977&partnerID=40&md5=0197784a9f4f3c1c0364eb8176933242
Parole chiave: Biosensors, Dna Sensing, Genomic Dna, Pcr-Free, Peptide Nucleic Acids, Surface-Plasmon Resonance, Biosensing, Certified Reference Materials, Detection Methods, Direct Detection, Dna Detection, Enhanced Surface, Genetically Modified, Labeling Steps, Selectivity And Sensitivity, Target Sequences, Ultrasensitive Detection, Biomolecules, Dna Sequences, Nanoparticles, Polymerase Chain Reaction, Surface Plasmon Resonance, Complementary Dna, Analytic Method, Controlled Study, Dna Determination, Gene Amplification, Gene Targeting, Image Enhancement, Sensitivity Analysis, Base Sequence, Recombinant, Gold, Metal Nanoparticles, Plants, Soybeans,
Affiliazioni:
*** IBB - CNR ***
Dipartimento di Scienze Chimiche, Università di Catania, Viale Andrea Doria 6, I-95125 Catania, Italy
Dipartimento di Chimica Organica ed Industriale, Università di Parma, Viale G.P. Usberti 17/a, I-43100 Parma, Italy
Neotron S.p.a., Stradello Aggazzotti 104, I-41010 Modena, Italy
Scuola Superiore di Catania, C/o Dipartimento di Scienze Chimiche, Università di Catania, Viale Andrea Doria 6, Catania, Italy
Istituto Biostrutture e Bioimmagini, CNR, Viale A. Doria 6, Catania, Italy
Riferimenti:
Arena, G., Contino, A., Longo, E., Sgarlata, C., Spoto, G., Zito, V., (2004) Chem. Commun., 16, pp. 1812-181
Berdal, K.G., Bøydler, C., Tengs, T., Holst-Jensen, A., (2008) Eur. Food Res. Technol., 227, pp. 1149-1157
Burns, C., Spendel, W.U., Puckett, S., Pacey, G.E., (2006) Talanta, 69, pp. 873-876
D'Agata, R., Corradini, R., Grasso, G., Marchelli, R., Spoto, G., (2008) ChemBioChem, 9, pp. 2067-2070
D'Agata, R., Grasso, G., Iacono, G., Spoto, G., Vecchio, G., (2006) Org. Biomol. Chem., 4, pp. 610-612
Dos Santos Riccardi, C., Kranz, C., Kowalik, J., Yamanaka, H., Mizaikoff, B., Josowicz, M., (2008) Anal. Chem., 80, pp. 237-245
Germini, A., Rossi, S., Zanetti, A., Corradini, R., Fogher, C., Marchelli, R., (2005) J. Agric. Food Chem., 53, pp. 3958-3962
Gibson, G., (2008) Nat. Rev. Genet., 9, pp. 575-581
(2009), http://ec.europa.eu/food/dyna/gm_register/index_en.cfm, GM Food & Feed, Community Register of GM Food and Feed, Event MON 40-3-2. (accessed 20.11.09)Goodrich, T.T., Lee, H.J., Corn, R.M., (2004) J. Am. Chem. Soc., 126, pp. 4086-4087
Grabar, K.C., Freeman, R.G., Hommer, M.B., Natan, M.J., (1995) Anal. Chem., 67, pp. 735-743
Grasso, G., Bush, A.I., D'Agata, R., Rizzarelli, E., Spoto, G., (2009) Eur. Biophys. J., Biophys. Lett., 38, pp. 407-414
Grasso, G., D'Agata, R., Zanoli, L., Spoto, G., (2009) Microchem. J., 93, pp. 82-86
Grasso, G., Fragai, M., Rizzarelli, E., Spoto, G., Yeo, K.J., (2006) J. Mass Spectrom., 41, pp. 1561-1569
Haiss, W., Thanh, N.T.K., Aveyard, J., Fernig, D.G., (2007) Anal. Chem., 79, pp. 4215-4221
He, L., Musick, M.D., Nicewarner, S.R., Salinas, F.G., Benkovic, S.J., Natan, M.J., Keating, C.D., (2000) J. Am. Chem. Soc., 122, pp. 9071-9077
Ho, H.A., Doré, K., Boissinot, M., Bergeron, M.G., Tanguay, R.M., Boudreau, D., Leclerc, M., (2005) J. Am. Chem. Soc., 127, pp. 12673-12676
(2005), ISO 21569:, Foodstuffs - Methods of Analysis for the Detection of Genetically Modified Organisms and Derived Products - Qualitative Nucleic Acid Based Methods(2005), ISO 21570:, Foodstuffs - Methods of Analysis for the Detection of Genetically Modified Organisms and Derived Products - Quantitative Nucleic Acid Based MethodsLee, H.J., Wark, A.W., Corn, A.W., (2006) Langmuir, 22, pp. 5241-5250
Li-Qiang, C., Foerch, R., Knoll, W., (2007) Angew. Chem. Int. Ed., 46, pp. 4944-4947
Minunni, M., Tombelli, S., Mascini, M., (2007) Anal. Lett., 40, pp. 1360-1370
Perkel, J., (2008) Nat. Methods, 5, pp. 447-453
Rosi, N.L., Mirkin, C.A., (2005) Chem. Rev., 105, pp. 1547-1562
Rossi, S., Scaravelli, E., Germini, A., Corradini, R., Fogher, C., Marchelli, R., (2006) Eur. Food Res. Technol., 223, pp. 1-6
Rothenhäusler, B., Knoll, W., (1988) Nature, 332, pp. 615-617
Ruemmele, J.A., Golden, M.S., Gao, Y., Cornelius, E.M., Anderson, M.E., Postelnicu, L., Georgiadis, R.M., (2008) Anal. Chem., 80, pp. 4752-4756
Sassolas, A., Leca-Bouvier, B.D., Blum, L.J., (2008) Chem. Rev., 108, pp. 109-139
Scarano, S., Mascini, M., Turner, A.P.F., Minunni, M., (2009) Biosens. Bioelectron.
Shi, L., Perkins, R.G., Fang, H., Tong, W., (2008) Curr. Opin. Biotechnol., 19, pp. 10-18
Shultz, J.L., Kurunam, D., Shopinski, D., Iqbal, M.J., Kazi, S., Zobrist, K., Bashir, R., Lightfoot, D.A., (2006) Nucl. Acids Res., 34, pp. D758-D765
Sohni, Y., Kanjilal, S., Kapur, V., (2008) Clin. Biochem., 41, pp. 640-644
Stoeva, S.I., Lee, J., Thaxton, C.S., Mirkin, C.A., (2006) Angew. Chem. Int. Ed., 45, pp. 3303-3306
Storhoff, J.J., Lucas, A.D., Garimella, V., Bao, Y.P., Müller, U.R., (2004) Nat. Biotechnol., 22, pp. 883-887
Sujit, K.G., Tarasankar, P., (2007) Chem. Rev., 107, pp. 4797-4862
Totsingan, F., Rossi, S., Corradini, R., Tedeschi, T., Sforza, S., Juris, A., Scaravelli, E., Marchelli, R., (2008) Org. Biomol. Chem., 6, pp. 1232-1237
Wark, A.W., Lee, H.J., Corn, R.M., (2008) Angew. Chem. Int. Ed., 47, pp. 644-652
Yang, K., Moon, J.-K., Jeong, N., Back, K., Kim, H.M., Jeong, S.C., (2008) Genomics, 92, pp. 52-59
Zanoli, L., D'Agata, R., Spoto, G., (2008) Minerva Biotechnol., 20, pp. 165-174
Zhang, N., Appella, D.H., (2007) J. Am. Chem. Soc., 129, pp. 8424-8425
Zhao, W., Brook, M.A., Li, Y.F., (2008) ChemBioChem, 9, pp. 2363-2371
Zhu, D., Tang, Y., Xing, D., Chen, W.R., (2008) Anal. Chem., 80, pp. 3566-3571
Biosens Bioelectron (ISSN: 0956-5663, 1873-4235electronic), 2010 May 15; 25(9): 2095-2100.
Tipo di articolo: Journal Article,
Impact factor: 5.361, Impact factor a 5 anni: 5.397
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-77951622977&partnerID=40&md5=0197784a9f4f3c1c0364eb8176933242
Parole chiave: Biosensors, Dna Sensing, Genomic Dna, Pcr-Free, Peptide Nucleic Acids, Surface-Plasmon Resonance, Biosensing, Certified Reference Materials, Detection Methods, Direct Detection, Dna Detection, Enhanced Surface, Genetically Modified, Labeling Steps, Selectivity And Sensitivity, Target Sequences, Ultrasensitive Detection, Biomolecules, Dna Sequences, Nanoparticles, Polymerase Chain Reaction, Surface Plasmon Resonance, Complementary Dna, Analytic Method, Controlled Study, Dna Determination, Gene Amplification, Gene Targeting, Image Enhancement, Sensitivity Analysis, Base Sequence, Recombinant, Gold, Metal Nanoparticles, Plants, Soybeans,
Affiliazioni:
*** IBB - CNR ***
Dipartimento di Scienze Chimiche, Università di Catania, Viale Andrea Doria 6, I-95125 Catania, Italy
Dipartimento di Chimica Organica ed Industriale, Università di Parma, Viale G.P. Usberti 17/a, I-43100 Parma, Italy
Neotron S.p.a., Stradello Aggazzotti 104, I-41010 Modena, Italy
Scuola Superiore di Catania, C/o Dipartimento di Scienze Chimiche, Università di Catania, Viale Andrea Doria 6, Catania, Italy
Istituto Biostrutture e Bioimmagini, CNR, Viale A. Doria 6, Catania, Italy
Riferimenti:
Arena, G., Contino, A., Longo, E., Sgarlata, C., Spoto, G., Zito, V., (2004) Chem. Commun., 16, pp. 1812-181
Berdal, K.G., Bøydler, C., Tengs, T., Holst-Jensen, A., (2008) Eur. Food Res. Technol., 227, pp. 1149-1157
Burns, C., Spendel, W.U., Puckett, S., Pacey, G.E., (2006) Talanta, 69, pp. 873-876
D'Agata, R., Corradini, R., Grasso, G., Marchelli, R., Spoto, G., (2008) ChemBioChem, 9, pp. 2067-2070
D'Agata, R., Grasso, G., Iacono, G., Spoto, G., Vecchio, G., (2006) Org. Biomol. Chem., 4, pp. 610-612
Dos Santos Riccardi, C., Kranz, C., Kowalik, J., Yamanaka, H., Mizaikoff, B., Josowicz, M., (2008) Anal. Chem., 80, pp. 237-245
Germini, A., Rossi, S., Zanetti, A., Corradini, R., Fogher, C., Marchelli, R., (2005) J. Agric. Food Chem., 53, pp. 3958-3962
Gibson, G., (2008) Nat. Rev. Genet., 9, pp. 575-581
(2009), http://ec.europa.eu/food/dyna/gm_register/index_en.cfm, GM Food & Feed, Community Register of GM Food and Feed, Event MON 40-3-2. (accessed 20.11.09)Goodrich, T.T., Lee, H.J., Corn, R.M., (2004) J. Am. Chem. Soc., 126, pp. 4086-4087
Grabar, K.C., Freeman, R.G., Hommer, M.B., Natan, M.J., (1995) Anal. Chem., 67, pp. 735-743
Grasso, G., Bush, A.I., D'Agata, R., Rizzarelli, E., Spoto, G., (2009) Eur. Biophys. J., Biophys. Lett., 38, pp. 407-414
Grasso, G., D'Agata, R., Zanoli, L., Spoto, G., (2009) Microchem. J., 93, pp. 82-86
Grasso, G., Fragai, M., Rizzarelli, E., Spoto, G., Yeo, K.J., (2006) J. Mass Spectrom., 41, pp. 1561-1569
Haiss, W., Thanh, N.T.K., Aveyard, J., Fernig, D.G., (2007) Anal. Chem., 79, pp. 4215-4221
He, L., Musick, M.D., Nicewarner, S.R., Salinas, F.G., Benkovic, S.J., Natan, M.J., Keating, C.D., (2000) J. Am. Chem. Soc., 122, pp. 9071-9077
Ho, H.A., Doré, K., Boissinot, M., Bergeron, M.G., Tanguay, R.M., Boudreau, D., Leclerc, M., (2005) J. Am. Chem. Soc., 127, pp. 12673-12676
(2005), ISO 21569:, Foodstuffs - Methods of Analysis for the Detection of Genetically Modified Organisms and Derived Products - Qualitative Nucleic Acid Based Methods(2005), ISO 21570:, Foodstuffs - Methods of Analysis for the Detection of Genetically Modified Organisms and Derived Products - Quantitative Nucleic Acid Based MethodsLee, H.J., Wark, A.W., Corn, A.W., (2006) Langmuir, 22, pp. 5241-5250
Li-Qiang, C., Foerch, R., Knoll, W., (2007) Angew. Chem. Int. Ed., 46, pp. 4944-4947
Minunni, M., Tombelli, S., Mascini, M., (2007) Anal. Lett., 40, pp. 1360-1370
Perkel, J., (2008) Nat. Methods, 5, pp. 447-453
Rosi, N.L., Mirkin, C.A., (2005) Chem. Rev., 105, pp. 1547-1562
Rossi, S., Scaravelli, E., Germini, A., Corradini, R., Fogher, C., Marchelli, R., (2006) Eur. Food Res. Technol., 223, pp. 1-6
Rothenhäusler, B., Knoll, W., (1988) Nature, 332, pp. 615-617
Ruemmele, J.A., Golden, M.S., Gao, Y., Cornelius, E.M., Anderson, M.E., Postelnicu, L., Georgiadis, R.M., (2008) Anal. Chem., 80, pp. 4752-4756
Sassolas, A., Leca-Bouvier, B.D., Blum, L.J., (2008) Chem. Rev., 108, pp. 109-139
Scarano, S., Mascini, M., Turner, A.P.F., Minunni, M., (2009) Biosens. Bioelectron.
Shi, L., Perkins, R.G., Fang, H., Tong, W., (2008) Curr. Opin. Biotechnol., 19, pp. 10-18
Shultz, J.L., Kurunam, D., Shopinski, D., Iqbal, M.J., Kazi, S., Zobrist, K., Bashir, R., Lightfoot, D.A., (2006) Nucl. Acids Res., 34, pp. D758-D765
Sohni, Y., Kanjilal, S., Kapur, V., (2008) Clin. Biochem., 41, pp. 640-644
Stoeva, S.I., Lee, J., Thaxton, C.S., Mirkin, C.A., (2006) Angew. Chem. Int. Ed., 45, pp. 3303-3306
Storhoff, J.J., Lucas, A.D., Garimella, V., Bao, Y.P., Müller, U.R., (2004) Nat. Biotechnol., 22, pp. 883-887
Sujit, K.G., Tarasankar, P., (2007) Chem. Rev., 107, pp. 4797-4862
Totsingan, F., Rossi, S., Corradini, R., Tedeschi, T., Sforza, S., Juris, A., Scaravelli, E., Marchelli, R., (2008) Org. Biomol. Chem., 6, pp. 1232-1237
Wark, A.W., Lee, H.J., Corn, R.M., (2008) Angew. Chem. Int. Ed., 47, pp. 644-652
Yang, K., Moon, J.-K., Jeong, N., Back, K., Kim, H.M., Jeong, S.C., (2008) Genomics, 92, pp. 52-59
Zanoli, L., D'Agata, R., Spoto, G., (2008) Minerva Biotechnol., 20, pp. 165-174
Zhang, N., Appella, D.H., (2007) J. Am. Chem. Soc., 129, pp. 8424-8425
Zhao, W., Brook, M.A., Li, Y.F., (2008) ChemBioChem, 9, pp. 2363-2371
Zhu, D., Tang, Y., Xing, D., Chen, W.R., (2008) Anal. Chem., 80, pp. 3566-3571
Technologies today available for the DNA detection rely on a combination of labeled probes hybridized to target sequences which are amplified by polymerase chain reaction (PCR). Direct detection methods that eliminate the requirement for both PCR and labeling steps could afford faster, cheaper and simpler devices for the analysis of small amounts of unamplified DNA. In this work we describe the results obtained in the ultrasensitive detection of non-amplified genomic DNA. We analyzed certified reference materials containing different amounts of genetically modified DNA by using a detection method which combines the nanoparticle-enhanced surface plasmon resonance imaging (SPRI) biosensing to the peptide nucleic acids (PNAs) improved selectivity and sensitivity in targeting complementary DNA sequences. The method allowed us to obtain a 41 zM sensitivity in targeting genomic DNA even in the presence of a large excess of non-complementary DNA. (C) 2010 Elsevier B.V. All rights reserved.
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Impact Factor: 5.856
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Ruggiero A, Dattelbaum JD, Pennacchio A, Iozzino L, Staiano M, Luchansky MS, Der BS, Berisio R, D'Auria S, Vitagliano L
* Crystallization and preliminary X-ray crystallographic analysis of ligand-free and arginine-bound forms of Thermotoga maritima arginine-binding protein (253 visite)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2011 Nov 1; 67(11): 1462-1465.
Impact Factor: 0.506
Dettagli Esporta in BibTeX Esporta in EndNote
Roviello GN, Musumeci D, Bucci EM, Pedone C
* Synthesis and characterization of a novel ester-based nucleoamino acid for the assembly of aromatic nucleopeptides for biomedical applications (333 visite)
Int J Pharm (ISSN: 0378-5173, 1873-3476), 2011 Sep 30; 415(1-2): 206-210.
Impact Factor: 3.35
Dettagli Esporta in BibTeX Esporta in EndNote
Roviello GN, Crescenzo C, Capasso D, Di Gaetano S, Franco S, Bucci EM, Pedone C
* Synthesis of a novel Fmoc-protected nucleoaminoacid for the solid phase assembly of 4-piperidyl glycine/L-arginine-containing nucleopeptides and preliminary RNA interaction studies (260 visite)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2010 Sep; 39(3): 795-800.
Impact Factor: 4.106
Dettagli Esporta in BibTeX Esporta in EndNote
D'Agata R, Corradini R, Ferretti C, Zanoli L, Gatti M, Marchelli R, Spoto G
* Ultrasensitive detection of non-amplified genomic DNA (247 visite)
Lect Notes Electr Eng, 2010 May 15; 91LNEE: 485-488.
Impact Factor: 0
Dettagli Esporta in BibTeX Esporta in EndNote
D'Agata R, Corradini R, Ferretti C, Zanoli L, Gatti M, Marchelli R, Spoto G
* Detection Of Non Amplified Genomic Dna By Advanced Spri Methods (167 visite)
Chimica & L Industria, 2010; 7: 140-145.
Impact Factor: 0
Dettagli Esporta in BibTeX Esporta in EndNote
D'Antò V, Michelotti A, Esposito L, Zagari A, Liguori R, Sacchetti L
* Nonsynonimous mutation of catechol-O-methyl-transferase (COMT) gene in a patient with temporomandibular disorder (196 visite)
J Sci Med Sport (ISSN: 1440-2440), 2010; 13(6): 174-179.
Impact Factor: 3.194
Dettagli Esporta in BibTeX Esporta in EndNote
D'Agata R, Breveglieri G, Zanoli L, Borgatti M, Spoto G, Gambari R
* Surface Plasmon Resonance Imaging (SPR-I), peptide nucleic acid (PNA) probes and nanoparticle-enhancement for PCR-free ultrasensitive detection of beta-thalassemia mutations in human genomic DNA (193 visite)
International Journal Of Molecular Medicine (ISSN: 1107-3756), 2010; 26: N/D-N/D.
Impact Factor: 1.814
Dettagli Esporta in BibTeX Esporta in EndNote
Roviello GN, Musumeci D, Bucci EM, Castiglione M, Cesarani A, Pedone C, Piccialli G
* Evidences for complex formation between l-dabPNA and aegPNA (188 visite)
Bioorg Med Chem Lett (ISSN: 0960-894x, 1464-3405, 1464-3405electronic), 2008 Sep 1; 18(17): 4757-4760.
Impact Factor: 2.531
Dettagli Esporta in BibTeX Esporta in EndNote
D'Agata R, Corradini R, Grasso G, Marchelli R, Spoto G
* Ultrasensitive detection of DNA by PNA and nanoparticle-enhanced surface plasmon resonance imaging (248 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2008 Sep 1; 9(13): 2067-2070.
Impact Factor: 3.322
Dettagli Esporta in BibTeX Esporta in EndNote
Breveglieri G, Pensato S, Salvatori F, Saviano M, Pedone C, Romanelli A, Gambari R
* PNA-mediated alteration of mRNA splicing (206 visite)
Minerva Biotecnol (ISSN: 1120-4826), 2008; 20(4): 175-181.
Impact Factor: 0.1
Dettagli Esporta in BibTeX Esporta in EndNote
Marchelli R, Saviano M, Licandro E, Spoto G, Borgatti M, Gambari R
* PNAs targeting the "RNA world": Micro RNA next? (213 visite)
Minerva Biotecnol (ISSN: 1120-4826), 2008; 20(4): 183-188.
Impact Factor: 0.1
Dettagli Esporta in BibTeX Esporta in EndNote
Zanoli L, Dagata R, Spoto G
* Surface plasmon-based optical detection of DNA peptide nucleic acids (177 visite)
Minerva Biotecnol (ISSN: 1120-4826), 2008; 20(4): 165-174.
Impact Factor: 0.1
Dettagli Esporta in BibTeX Esporta in EndNote
Staiano M, Saviano M, Herman P, Grycznyski Z, Fini C, Varriale A, Parracino A, Kold AB, Rossi M, D'Auria S
* Time-resolved fluorescence spectroscopy and molecular dynamics simulations point out the effects of pressure on the stability and dynamics of the porcine odorant-binding protein (352 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2008; 89(4): 284-291.
Impact Factor: 2.823
Dettagli Esporta in BibTeX Esporta in EndNote
Moccia M, Musumeci D, Valente M, Roviello GN, Sapio R, Pedone C, Bucci EM
* Thermodynamic studies on PNA and PNA/DNA dendrimer formation (156 visite)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1525-7770), 2007; 26(8-9): 1173-1176.
Impact Factor: 0.723
Dettagli Esporta in BibTeX Esporta in EndNote
Roviello GN, Moccia M, Sapio R, Valente M, Bucci EM, Castiglione M, Pedone C, Perretta G, Benedetti E, Musumeci D
* Synthesis, Characterization And Hybridization Studies Of New Nucleo-Gamma-Peptides Based On Diaminobutyric Acid (286 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2006 Dec; 12(12): 829-835.
Impact Factor: 1.801
Dettagli Esporta in BibTeX Esporta in EndNote
Borgatti M, Boyd DD, Lampronti I, Bianchi N, Fabbri E, Saviano M, Romanelli A, Pedone C, Gambari R
* Decoy molecules based on PNA-DNA chimeras and targeting Sp1 transcription factors inhibit the activity of urokinase-type plasminogen activator receptor (uPAR) promoter (248 visite)
Oncology Research (ISSN: 0965-0407), 2005; 15(7-8): 373-383.
Impact Factor: 1.844
Dettagli Esporta in BibTeX Esporta in EndNote
Borgatti M, Finotti A, Romanelli A, Saviano M, Bianchi N, Lampronti I, Lambertini E, Penolazzi L, Nastruzzi C, Mischiati C, Piva R, Pedone C, Gambari R
* Peptide nucleic acids (PNA)-DNA chimeras targeting transcription factors as a tool to modify gene expression (258 visite)
Curr Drug Targets (ISSN: 1389-4501), 2004 Nov; 5(8): 735-744.
Impact Factor: 4.104
Dettagli Esporta in BibTeX Esporta in EndNote
Cortesi R, Mischiati C, Borgatti M, Breda L, Romanelli A, Saviano M, Pedone C, Gambari R, Nastruzzi C
* Formulations for natural and peptide nucleic acids based on cationic polymeric submicron particles (261 visite)
The Aaps Journal (ISSN: 1522-1059, 1550-7416), 2004 Jan 20; 6(1): N/D-N/D.
Impact Factor: 1.938
Dettagli Esporta in BibTeX Esporta in EndNote
Musumeci D, Roviello GN, Valente M, Sapio R, Pedone C, Bucci EM
* New synthesis of PNA-3′DNA linker monomers, useful building blocks to obtain PNA/DNA chimeras (276 visite)
Biopolymers, 2004; 76(6): 535-542.
Impact Factor: 2.248
Dettagli Esporta in BibTeX Esporta in EndNote
Gambari R, Borgatti M, Romanelli A, Capasso D, Saviano M, Bianchi N, Lampronti I, Mischiati C, Pedone C
* Transcription factor decoy (TFD) activity of peptide nucleic acids (PNA)-DNA chimeras (148 visite)
International Journal Of Molecular Medicine (ISSN: 1107-3756), 2003; 12(Supplement1): N/D-N/D.
Impact Factor: 1.94
Dettagli Esporta in BibTeX Esporta in EndNote
Romanelli A, Pedone C, Saviano M, Bianchi N, Borgatti M, Mischiati C, Gambari R
* Molecular interactions between nuclear factor κB (NF-κB) transcription factors and a PNA-DNA chimera mimicking NF-κB binding sites (216 visite)
Eur J Biochem (ISSN: 0014-2956, 0014-2956print, 0014-2956linking), 2001 Dec; 268(23): 6066-6075.
Impact Factor: 2.849
Dettagli Esporta in BibTeX Esporta in EndNote
Romanelli A, Pedone C, Saviano M, Bianchi N, Borgatti M, Mischiati C, Gambari R
* Molecular interactions with nuclear factor kappaB (NF-kappaB) transcription factors of a PNA-DNA chimera mimicking NF-kappaB binding sites (268 visite)
Eur J Biochem (ISSN: 0014-2956print, 0014-2956linking), 2001 Dec; 268(23): 6066-6075.
Impact Factor: 4.779
Dettagli Esporta in BibTeX Esporta in EndNote
47 Records (39 escludendo Abstract e Conferenze).
Impact factor totale: 124.993 (114.254 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 129.201 (114.388 escludendo Abstract e Conferenze).
Impact factor totale: 124.993 (114.254 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 129.201 (114.388 escludendo Abstract e Conferenze).
Esporta in BibTeX Esporta in EndNote
Ultima modifica di Marco Comerci in data Thursday 19 March 2015, 19:54:49
191 visite. Ultima visita in data Tuesday 16 June 2020, 19:19:44
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