Performance evaluation of the fully engineered YAP-(S)PET scanner for small animal imaging
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Performance evaluation of the fully engineered YAP-(S)PET scanner for small animal imaging (346 views visite)

Del Guerra A, Bartoli A, Belcari N, Herbert D, Motta A, Vaiano A, Di Domenico G, Sabba N, Moretti E, Zavattini G, Lazzarotti M, Sensi L, Larobina M

2004 Ieee Nuclear Science Symposium Conference Record Vols 1 7, 2004; 5: 2990-2994.



Paper type Tipo di articolo: Journal Article,

Impact factor: 0, 5-year impact factor Impact factor a 5 anni: 0

Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-23844558348&partnerID=40&md5=d3f30611a8e3fa089de5a3f3365d31bc

Keywords Parole chiave: Algorithms, Computer Simulation, Crystals, Electron Beam Computed Tomography, Photodiodes, Thin Films, Animal Imaging, Lutetium Oxyorthosilicate (lso) Crystals, Phantoms, Pixellated Array, Living Systems Studies,

Affiliations Affiliazioni:

*** IBB - CNR ***
Department of Physics, Center of Excellence AmbiSEN, University of Pisa, Largo Pontecorvo, 3, I-56127 Pisa, Italy
Ingegneria dei Sistemi Elettronici S.r.l., Pisa, Italy
C.N.R - Istituto di Biostrutture e Bioimmagini, Napoli, Italy


References Riferimenti:

Del Guerra, A., Domenico, D., Scandola, M., Zavattini, G., High spatial ' resolution small animal YAPPET (1998) Nucl. Instr. and Meth. Phys. Res., A409, pp. 537-54

Del Guerra, A., Damiani, C., Di Domenico, G., Motta, A., Sartori, L., Zavattini, G., An integrated PET-SPECT small animal imager: Preliminary results (2000) IEEE Trans Nucl Sci, 47, pp. 1537-1540

I.S.E. Ingegneria dei Sistemi Elettronici s.r.l., Vecchiano, Pisa, ItalyDel Guerra, A., Di Domenico, G., Gambaccini, M., Moretti, E., Sabba, N., Zavattini, G., Simultaneous PET/SPECT imaging with the small animal YAP-(S)PET scanner (2002) 2002 Annual Conference of the Academy of Molecular Imaging, , October 23-27, San Diego, CA, (USA) (abstract)

Motta, A., Damiani, C., Del Guerra, A., Di Domenico, G., Zavattini, G., Use of a fast deconvolution em algorithm for 3-D imaging reconstruction with the YAP-PET tomograph (2002) Comp. Med. Im. and Graph, 26, pp. 293-302

(2001) NEMA Standards Publication NU2-2001: Performance Measurements of Positron Emission Tomographs, , Rosslyn, VA: National Electrical Manufactures Association

(1994) NEMA Standards Publication NU2-1994: Performance Measurements of Positron Emission Tomographs, , Washington, DC: National Electrical Manufactures Association

Yang, Y., Tai, Y.-C., Siegel, S., Newport, D.F., Bai, B., Li, Q., Leahy, R.M., Cherry, S.R., Optimization and performance evaluation of the microPET II scanner for in vivo small-animal imaging (2004) Phys. Med. Biol., 49, pp. 2527-2545



At the Department of Physics of the University of Pisa, a new and fully engineered version of the YAP-(S)PET small animal scanner has been recently installed. The new YAP-(S)PET is able to perform both PET and SPECT studies on small animals. The scanner is made up of four heads: each one is composed of a 4 x 4 cm(2) YAIO(3):Ce (or YAP:Ce) matrix of 20 x 20 elements, 2 x 2 x 25 mm(3) each, coupled to a PS-PMT (Hamamatsu R2486). The four modules are positioned on a rotating gantry. The switching to the SPECT modality is easily made by mounting a high resolution parallel hole (0.6 mm O, 0.15 mm septum) lead collimator in front of each crystal. This paper reports the performance of the system in termsi of absolute sensitivity and spatial resolution for both PET and SPECT modalities. The scatter fraction and noise-equivalent count rate (NEC) for a mouse phantom for different energy windows have been measured. Images of phantoms and animals are also presented.
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