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Chitin-induced activation of immune signaling by the rice receptor CEBiP relies on a unique sandwich-type dimerization (153 visite)

Hayafune M, Berisio R, Marchetti R, Silipo A, Kayama M, Desaki Y, Arima S, Squeglia F, Ruggiero A, Tokuyasu K, Molinaro A, Kaku H, Shibuya N

Proc Natl Acad Sci U S A (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2014 Jan 21; 111(3): E404-E404.

Tipo di articolo: Journal Article,

Impact factor: 9.674

Impact factor a 5 anni: 10.563


Parole chiave: Chitin Signaling, Lysm-Receptor, Mti Pti, Plant Immunity, Receptor-Ligand Interaction, Amino Acid, Binding Protein, Chitin Elicitor Binding Protein, Oligosaccharide, Pattern Recognition Receptor, Reactive Oxygen Metabolite, Unclassified Drug, Affinity Labeling, Amino Acid Sequence, Article, Binding Affinity, Conformational Transition, Controlled Study, Deletion Mutant, Dimerization, Epitope Mapping, Hidden Markov Model, Hydrogen Bond, Microsome Membrane, Molecular Docking, Molecular Dynamics, Molecular Interaction, Molecular Mechanics, Molecular Model, Molecular Recognition, Nicotiana Benthamiana, Nonhuman, Priority Journal, Protein Function, Protein Motif, Proton Nuclear Magnetic Resonance, Signal Transduction, Site Directed Mutagenesis, Transient Expression, Amino Acid Motifs, Binding Sites, Lysine, Magnetic Resonance Spectroscopy, Molecular Sequence Data, Site-Directed, Oryza Sativa, Plant Proteins, Protein Multimerization, Protein Structure, Tertiary, Reactive Oxygen Species, Cell Surface, Sequence Homology, Tobacco, Chitin Chemistry, Epitopes Immunology, Lysine Chemistry, Oligosaccharides Chemistry, Oryza Sativa Immunology Metabolism, Plant Proteins Metabolism, Reactive Oxygen Species Metabolism, Cell Surface Metabolism, Receptor?igand Interaction, Receptor? Igand Interaction, Receptor Igand Interaction, Receptor Ligand Interaction,

Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84892922883&partnerID=40&md5=585fe746a199b04bbd61524402949320

Perception of microbe-associated molecular patterns (MAMPs) through pattern recognition receptors (PRRs) triggers various defense responses in plants. This MAMP-triggered immunity plays a major role in the plant resistance against various pathogens. To clarify the molecular basis of the specific recognition of chitin oligosaccharides by the rice PRR, CEBiP (chitin-elicitor binding protein), as well as the formation and activation of the receptor complex, biochemical, NMR spectroscopic, and computational studies were performed. Deletion and domain-swapping experiments showed that the central lysine motif in the ectodomain of CEBiP is essential for the binding of chitin oligosaccharides. Epitope mapping by NMR spectroscopy indicated the preferential binding of longer-chain chitin oligosaccharides, such as heptamer-octamer, to CEBiP, and also the importance of N-acetyl groups for the binding. Molecular modeling/docking studies clarified the molecular interaction between CEBiP and chitin oligosaccharides and indicated the importance of Ile (122) in the central lysine motif region for ligand binding, a notion supported by site-directed mutagenesis. Based on these results, it was indicated that two CEBiP molecules simultaneously bind to one chitin oligosaccharide from the opposite side, resulting in the dimerization of CEBiP. The model was further supported by the observations that the addition of (GlcNAc) (8) induced dimerization of the ectodomain of CEBiP in vitro, and the dimerization and (GlcNAc) (8) -induced reactive oxygen generation were also inhibited by a unique oligosaccharide, (GlcN beta 1, 4GlcNAc) (4), which is supposed to have N-acetyl groups only on one side of the molecule. Based on these observations, we proposed a hypothetical model for the ligand-induced activation of a receptor complex, involving both CEBiP and Oryza sativa chitin-elicitor receptor kinase-1
*** IBB - CNR ***

Department of Life Sciences, School of Agriculture, Meiji University, Kawasaki 214-8571, Japan

Institute of Biostructures and Bioimaging, National Research Council, I-80134 Naples, Italy

Department of Chemical Sciences, Universita di Napoli Federico II, I-80126 Naples, Italy

Food Resource Division, National Food Research Institute, Tsukuba, Ibaraki 305-8642, Japan
Boller, T., He, S.Y., Innate immunity in plants: An arms race between pattern recognition receptors in plants and effectors in microbial pathogens (2009) Science, 324 (5928), pp. 742-74

Zipfel, C., Pattern-recognition receptors in plant innate immunity (2008) Curr Opin Immunol, 20 (1), pp. 10-16

Kwon, C., Panstruga, R., Schulze-Lefert, P., Les liaisons dangereuses: Immunological synapse formation in animals and plants (2008) Trends Immunol, 29 (4), pp. 159-166

Nürnberger, T., Brunner, F., Kemmerling, B., Piater, L., Innate immunity in plants and animals: Striking similarities and obvious differences (2004) Immunol Rev, 198, pp. 249-266

Boller, T., Felix, G., A renaissance of elicitors: Perception of microbe-associated molecular patterns and danger signals by pattern-recognition receptors (2009) Annu Rev Plant Biol, 60, pp. 379-406

Kaku, H., Plant cells recognize chitin fragments for defense signaling through a plasma membrane receptor (2006) Proc Natl Acad Sci USA, 103 (29), pp. 11086-11091

Miya, A., CERK1, a LysM receptor kinase, is essential for chitin elicitor signaling in Arabidopsis (2007) Proc Natl Acad Sci USA, 104 (49), pp. 19613-19618

Wan, J., A LysM receptor-like kinase plays a critical role in chitin signaling and fungal resistance in Arabidopsis (2008) Plant Cell, 20 (2), pp. 471-481

Wan, J.R., LYK4, a lysin motif receptor-like kinase, is important for chitin signaling and plant innate immunity in Arabidopsis (2012) Plant Physiol, 160 (1), pp. 396-406

Shimizu, T., Two LysM receptor molecules, CEBiP and OsCERK1, cooperatively regulate chitin elicitor signaling in rice (2010) Plant J, 64 (2), pp. 204-214

Buist, G., Steen, A., Kok, J., Kuipers, O.P., LysM, a widely distributed protein motif for binding to (peptido) glycans (2008) Mol Microbiol, 68 (4), pp. 838-847

Shinya, T., Functional characterization of CEBiP and CERK1 homologs in arabidopsis and rice reveals the presence of different chitin receptor systems in plants (2012) Plant Cell Physiol, 53 (10), pp. 1696-1706

Liu, B., Lysin motif-containing proteins LYP4 and LYP6 play dual roles in peptidoglycan and chitin perception in rice innate immunity (2012) Plant Cell, 24 (8), pp. 3406-3419

Willmann, R., Arabidopsis lysin-motif proteins LYM1 LYM3 CERK1 mediate bacterial peptidoglycan sensing and immunity to bacterial infection (2011) Proc Natl Acad Sci USA, 108 (49), pp. 19824-19829

Shinya, T., Characterization of receptor proteins using affinity cross-linking with biotinylated ligands (2010) Plant Cell Physiol, 51 (2), pp. 262-270

Punta, M., The Pfam protein families database (2012) Nucleic Acids Res, 40, pp. D290-D301. , Database issue

Fliegmann, J., Biochemical and phylogenetic analysis of CEBiP-like LysM domain-containing extracellular proteins in higher plants (2011) Plant Physiol Biochem, 49 (7), pp. 709-720

Meyer, B., Peters, T., NMR spectroscopy techniques for screening and identifying ligand binding to protein receptors (2003) Angew Chem Int Ed Engl, 42 (8), pp. 864-890

Squeglia, F., Chemical basis of peptidoglycan discrimination by PrkC, a key kinase involved in bacterial resuscitation from dormancy (2011) J Am Chem Soc, 133 (51), pp. 20676-20679

Marchetti, R., Burkholderia cenocepacia lectin A binding to heptoses from the bacterial lipopolysaccharide (2012) Glycobiology, 22 (10), pp. 1387-1398

Silipo, A., NMR spectroscopic analysis reveals extensive binding interactions of complex xyloglucan oligosaccharides with the Cellvibrio japonicus glycoside hydrolase family 31 a-xylosidase (2012) Chemistry, 18 (42), pp. 13395-13404

Claasen, B., Axmann, M., Meinecke, R., Meyer, B., Direct observation of ligand binding to membrane proteins in living cells by a saturation transfer double difference (STDD) NMR spectroscopy method shows a significantly higher affinity of integrin alpha (IIb) beta3 in native platelets than in liposomes (2005) J Am Chem Soc, 127 (3), pp. 916-919

Haselhorst, T., Direct detection of ligand binding to Sepharose-immobilised protein using saturation transfer double difference (STDD) NMR spectroscopy (2007) Biochem Biophys Res Commun, 359 (4), pp. 866-870

Assadi-Porter, F.M., Direct NMR detection of the binding of functional ligands to the human sweet receptor, a heterodimeric family 3 GPCR (2008) J Am Chem Soc, 130 (23), pp. 7212-7213

Szczepina, M.G., Bleile, D.W., Pinto, B.M., Investigation of the binding of a carbohydrate-mimetic peptide to its complementary anticarbohydrate antibody by STD-NMR spectroscopy and molecular-dynamics simulations (2011) Chemistry, 17 (41), pp. 11446-11455

Angulo, J., Saturation transfer difference (STD) NMR spectroscopy characterization of dual binding mode of a mannose disaccharide to DC-SIGN (2008) Chem-BioChem, 9 (14), pp. 2225-2227

Enríquez-Navas, P.M., Marradi, M., Padro, D., Angulo, J., Penadés, S., A solution NMR study of the interactions of oligomannosides and the anti-HIV-1 2G12 antibody reveals distinct binding modes for branched ligands (2011) Chemistry, 17 (5), pp. 1547-1560

Mayer, M., James, T.L., NMR-based characterization of phenothiazines as a RNA binding scaffold (2004) J Am Chem Soc, 126 (13), pp. 4453-4460

Johnson, M.A., Pinto, B.M., NMR spectroscopic and molecular modeling studies of protein-carbohydrate and protein-peptide interactions (2004) Carbohydr Res, 339 (5), pp. 907-928

Jimenez-Barbero, J., (2002) NMR Spectroscopy of Glycoconjugates, , ed Peters T Wiley, Weinheim

Neuhaus, D., (2000) The Nuclear Overhauser Effect in Structural and Conformational Analysis, , ed Williamson MP Wiley, New York

Liu, T.T., Chitin-induced dimerization activates a plant immune receptor (2012) Science, 336 (6085), pp. 1160-1164

Shibuya, N., Minami, E., Oligosaccharide signalling for defense responses in plant (2001) Physiol Mol Plant Pathol, 59 (5), pp. 223-233

Yamada, A., Shibuya, N., Kodama, O., Akatsuka, T., Induction of phytoalexin formation in suspension-cultured rice cells by N-acetyl-chitooligosaccharides (1993) Biosci Biotechnol Biochem, 57 (3), pp. 405-409

Nishizawa, Y., Regulation of the chitinase gene expression in suspensioncultured rice cells by N-acetylchitooligosaccharides: Differences in the signal transduction pathways leading to the activation of elicitor-responsive genes (1999) Plant Mol Biol, 39 (5), pp. 907-914

Hubbard, S.R., Till, J.H., Protein tyrosine kinase structure and function (2000) Annu Rev Biochem, 69, pp. 373-398

Heldin, C.H., Dimerization of cell surface receptors in signal transduction (1995) Cell, 80 (2), pp. 213-223

Botos, I., Segal, D.M., Davies, D.R., The structural biology of Toll-like receptors (2011) Structure, 19 (4), pp. 447-459

Faulkner, C., LYM2-dependent chitin perception limits molecular flux via plasmodesmata (2013) Proc Natl Acad Sci USA, 110 (22), pp. 9166-9170

Narusaka, Y., Presence of LYM2 dependent but CERK1 independent disease resistance in Arabidopsis (2013) Plant Signal Behav, 8 (9), pp. e25345

Tokuyasu, K., Mori, Y., Kitagawa, Y., Hayashi, K., (1999) 2-methyl-(4-O-(2-amino-2-deoxy-.beta.-Glucopyranosyl)-1, 2-dideoxy-.alpha.-glucopyrano) (2, 1-D)-2-oxazoline and its Salt, 50% Deacetylated Chitin Or its Oligosaccharide and Salt Thereof, , US Patent 6, 437, 107

Kobayashi, S., Kiyosada, T., Shoda, S., Synthesis of artificial chitin: Irreversible catalytic behavior of a glycosyl hydrolase through a transition state analogue substrate (1996) J Am Chem Soc, 118 (51), pp. 13113-13114

Tsukada, K., Rice receptor for chitin oligosaccharide elicitor does not couple to heterotrimeric G-protein: Elicitor responses of suspension cultured rice cells from Daikoku dwarf (d1) mutants lacking a functional G-protein a-subunit (2002) Physiol Plant, 116 (3), pp. 373-382

Curtis, M.D., Grossniklaus, U., A gateway cloning vector set for high-throughput functional analysis of genes in planta (2003) Plant Physiol, 133 (2), pp. 462-469

Sainsbury, F., Thuenemann, E.C., Lomonossoff, G.P., PEAQ: Versatile expression vectors for easy and quick transient expression of heterologous proteins in plants (2009) Plant Biotechnol J, 7 (7), pp. 682-693

Shibuya, N., Kaku, H., Kuchitsu, K., Maliarik, M.J., Identification of a novel highaffinity binding site for N-acetylchitooligosaccharide elicitor in the membrane fraction from suspension-cultured rice cells (1993) FEBS Lett, 329 (1-2), pp. 75-78

Schwacke, R., Hager, A., Fungal elicitors induce a transient release of active oxygen species from cultured spruce cells that is dependent on Ca (2+) and proteinkinase activity (1992) Planta, 187 (1), pp. 136-141

Desaki, Y., Bacterial lipopolysaccharides induce defense responses associated with programmed cell death in rice cells (2006) Plant Cell Physiol, 47 (11), pp. 1530-1540

Van Der Spoel, D., GROMACS: Fast, flexible, and free (2005) J Comput Chem, 26 (16), pp. 1701-1718

States, D.J., Haberkorn, R.A., Ruben, D.J., A two-dimensional nuclear overhauser experiment with pure absorption phase in 4 quadrants (1982) J Magn Reson, 48 (2), pp. 286-292

Asensio, J.L., Jimenez-Barbero, J., The use of the AMBER force field in conformational analysis of carbohydrate molecules: Determination of the solution conformation of methyl a-lactoside by NMR spectroscopy, assisted by molecular mechanics and dynamics calculations (1995) Biopolymers, 35 (1), pp. 55-73

Bernardi, A., Second-generation mimics of ganglioside GM1 oligosaccharide: A three-dimensional view of their interactions with bacterial enterotoxins by NMR and computational methods (2002) Chemistry, 8 (20), pp. 4598-4612

Corzana, F., The pattern of distribution of amino groups modulates the structure and dynamics of natural aminoglycosides: Implications for RNA recognition (2007) J Am Chem Soc, 129 (10), pp. 2849-2865

Boller, T., He, S. Y., Innate immunity in plants: An arms race between pattern recognition receptors in plants and effectors in microbial pathogens (2009) Science, 324 (5928), pp. 742-74

N rnberger, T., Brunner, F., Kemmerling, B., Piater, L., Innate immunity in plants and animals: Striking similarities and obvious differences (2004) Immunol Rev, 198, pp. 249-266

Wan, J. R., LYK4, a lysin motif receptor-like kinase, is important for chitin signaling and plant innate immunity in Arabidopsis (2012) Plant Physiol, 160 (1), pp. 396-406

Assadi-Porter, F. M., Direct NMR detection of the binding of functional ligands to the human sweet receptor, a heterodimeric family 3 GPCR (2008) J Am Chem Soc, 130 (23), pp. 7212-7213

Szczepina, M. G., Bleile, D. W., Pinto, B. M., Investigation of the binding of a carbohydrate-mimetic peptide to its complementary anticarbohydrate antibody by STD-NMR spectroscopy and molecular-dynamics simulations (2011) Chemistry, 17 (41), pp. 11446-11455

Enr quez-Navas, P. M., Marradi, M., Padro, D., Angulo, J., Penad s, S., A solution NMR study of the interactions of oligomannosides and the anti-HIV-1 2G12 antibody reveals distinct binding modes for branched ligands (2011) Chemistry, 17 (5), pp. 1547-1560

Johnson, M. A., Pinto, B. M., NMR spectroscopic and molecular modeling studies of protein-carbohydrate and protein-peptide interactions (2004) Carbohydr Res, 339 (5), pp. 907-928

Liu, T. T., Chitin-induced dimerization activates a plant immune receptor (2012) Science, 336 (6085), pp. 1160-1164

Hubbard, S. R., Till, J. H., Protein tyrosine kinase structure and function (2000) Annu Rev Biochem, 69, pp. 373-398

Heldin, C. H., Dimerization of cell surface receptors in signal transduction (1995) Cell, 80 (2), pp. 213-223

Curtis, M. D., Grossniklaus, U., A gateway cloning vector set for high-throughput functional analysis of genes in planta (2003) Plant Physiol, 133 (2), pp. 462-469

States, D. J., Haberkorn, R. A., Ruben, D. J., A two-dimensional nuclear overhauser experiment with pure absorption phase in 4 quadrants (1982) J Magn Reson, 48 (2), pp. 286-292

Asensio, J. L., Jimenez-Barbero, J., The use of the AMBER force field in conformational analysis of carbohydrate molecules: Determination of the solution conformation of methyl -lactoside by NMR spectroscopy, assisted by molecular mechanics and dynamics calculations (1995) Biopolymers, 35 (1), pp. 55-73

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And Life Sciencesjournal Of Chromatography B Analytical Technologies In The Biomedical, 2004 Feb 5; 800(1-2): 127-133.
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D'Amore M, Improta R, Barone V
* Conformational behavior and magnetic properties of a nitroxide amino acid derivative in vacuo and in aqueous solution (91 visite)
J Phys Chem A (ISSN: 1089-5639, 1520-5215electronic), 2003; 107(32): 6264-6269.
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Caliendo G, Fiorino F, Grieco P, Perissutti E, De Luca S, Giuliano A, Santelli G, Califano D, Severino B, Santagada V
Synthesis and biological activity of pseudopeptides inhibitors of Ras farnesyl transferase containing unconventional amino acids (118 visite)
Farmaco (ISSN: 0014-827x), 1999 Nov; 54(11-12): 785-790.
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Campagna T, Grasso G, Rizzarelli E, Vecchio G
L- and D-cysteine derivatives of β-cyclodextrin: Different molecular recognition properties of their copper(II) complexes for amino acids (114 visite)
Inorg Chim Acta (ISSN: 0020-1693), 1998; 275-276: 395-400.
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Benedetti E, Iacovino R, Pedone C, Rossi F, Saviano M, Isernia C, Montesarchio D, DeNapoli L, Piccialli G
β-Amino acid residues: Conformational characterization of an N- and C-protected homo-β-(S)-leucine (80 visite)
International Journal Of Peptide Research And Therapeutics (ISSN: 0929-5666, 1573-3149), 1997 Jun; 4(3): 129-134.
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Crisma M, Formaggio F, Valle G, Toniolo C, Saviano M, Iacovino R, Zaccaro L, Benedetti E
Experimental evidence at atomic resolution for intramolecular N- H···π (phenyl) interactions in a family of amino acid derivatives (114 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1997; 42(1): 1-6.
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Bonomo RP, Pedotti S, Vecchio G, Rizzarelli E
Molecular Recognition of Amino Acids by Copper(II) Complexes of 6A, 6X-Diamino-6A, 6 X-dideoxy-β-cyclodextrin (X = B, C, D) (84 visite)
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 1996 Nov 6; 35(23): 6873-6877.
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Pavone V, Di Blasio B, Lombardi A, Maglio O, Isernia C, Pedone C, Benedetti E, Altmann E, Mutter M
Non coded C alpha, alpha-disubstituted amino acids. X-ray diffraction analysis of a dipeptide containing (S)-alpha-methylserine (106 visite)
Int J Pept Protein Res (ISSN: 0367-8377, 0367-8377print, 0367-8377linking), 1993 Jan; 41(1): 15-20.
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Lombardi A, Maglio O, Pavone B, Di Blasio V, Saviano M, Nastri F, Pedone C, Benedetti E
Pt(II) Complexes of Amino Acids and Peptides. III. X-Ray Diffraction Study of trans-[Cl-(Ph3P)-Pt-(H-Aib-O-)] (99 visite)
Inorg Chim Acta, 1993; 204: 87-92.
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Lombardi A, Maglio O, Benedetti B, Di Blasio E, Saviano M, Nastri F, Pedone C, Pavone V
Pt(II) Complexes of Amino Acids and Peptides. II. Structural Analysis of trans-[Cl2-Pt-(H-Aib-OH)2] (108 visite)
Inorg Chim Acta, 1992; 196: 241-246.
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34 Records (33 escludendo Abstract e Conferenze).
Impact factor totale: 100.708 (97.825 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 101.538 (98.829 escludendo Abstract e Conferenze).







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