Functional Binding Surface Of A Beta-Hairpin Vegf Receptor Targeting Peptide Determined By Nmr Spectroscopy In Living Cells (411 views visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2015 Jan 2; 21(1): 91-95.
Export to Esporta in BibTeX Export to Esporta in EndNote
Paper type Tipo di articolo: Journal Article, Research Support, Non-U. S. Gov'T,
Impact factor: 5.771, 5-year impact factor Impact factor a 5 anni: 5.572
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84920579931&partnerID=40&md5=3afe27390297fb1e8630bb85206fc464
Keywords Parole chiave: 15n Labelled Peptides, Living Cells, Nmr Spectroscopy, Peptide-Protein Interaction, Vegf Receptors, Cell Engineering, Cytology, Isotopes, Nuclear Magnetic Resonance Spectroscopy, Binding Surface, Functional Interaction, Receptor Targeting, Relaxation Measurements, Vascular Endothelial Growth Factor Receptor, Endothelial Cells, Nitrogen Isotopes, Agonists, Animals, Cell Line, Chemistry, Genetics, Metabolism, Biomolecular, Protein Interaction Domains And Motifs, Protein Structure, Secondary, Swine,
Affiliations Affiliazioni:
*** IBB - CNR ***
Dipartimento di Scienze e Tecnologie Ambientali, Biologiche e Farmaceutiche, Seconda Universitädegli Studi Napoli, via Vivaldi 46Caserta, Italy
Istituto di Biostrutture e Bioimmagini C.N.R., via Mezzocannone 16Napoli, Italy
Dipartimento di Farmacia, Università Degli Studi di Napoli Federico II, via Mezzocannone 16Napoli, Italy
References Riferimenti:
Carmeliet, P., (2005) Nature, 438, pp. 932-93
Ferrara, N., Gerber, H.P., Le Couter, J., (2003) Nat. Med., 9, pp. 669-676
Ferrara, N., (2000) Curr. Opin. Biotechnol., 11, pp. 617-624
Ferrara, N., Kerbel, R.S., (2005) Nature, 438, pp. 967-974
Maglione, D., Guerriero, V., Viglietto, G., Delli-Bovi, P., Persico, M.G., (1991) Proc. Natl. Acad. Sci. USA, 88, pp. 9267-9271
Fischer, Mazzone, M., Jonckx, B., Carmeliet, P., (2008) Nat. Rev. Cancer, 8, pp. 942-956
Cao, Y., (2009) Sci. Signaling, 2, p. re12
Wiesmann, C., Fuh, G., Christinger, H.W., Eigenbro, C., Wells, J.A., De Vos, A.M., (1998) Biochemistry, 37, pp. 17765-17772
Christinger, H.W., Fuh, G., De Vos, A.M., Wiesmann, C., (2004) J. Biol. Chem., 279, pp. 10382-10388
D'Andrea, L.D., Laccarino, G., Fattorusso, R., Sorriento, D., Carannante, C., Capasso, D., Trimarco, B., Pedone, C., (2005) Proc. Natl. Acad. Sci. USA, 102, pp. 14215-14220
Diana, D., Ziaco, B., Colombo, G., Scarabelli, G., Romanelli, A., Pedone, C., Fattorusso, R., D'Andrea, L.D., (2008) Chem. Eur. J., 14, pp. 4164-4166
Diana, D., Basile, A., De Rosa, L., Di Stasi, R., Auriemma, S., Arra, C., Pedone, C., D'Andrea, L.D., (2011) J. Biol. Chem., 286, pp. 41680-41691
Basile, A., Del Gatto, A., Diana, D., Di Stasi, R., Falco, A., Festa, M., Rosati, A., D'Andrea, L.D., (2011) J. Med. Chem., 54, pp. 1391-1400
De Rosa, L., Diana, D., Basile, A., Russomanno, A., Isernia, C., Turco, M.C., Fattorusso, R., D'Andrea, L.D., (2014) Eur. J. Med. Chem., 73, pp. 210-216
Ito, Y., Selenko, P., (2010) Curr. Opin. Struct. Biol., 20, pp. 640-648
Reckel, S., Lohr, F., Dotsch, V., (2005) Chem Bio Chem, 6, pp. 1601-1606
Serber, Z., Keatinge-Clay, A.T., Kelly, A.E., Miller, S.M., Dotsch, V., (2001) J. Am. Chem. Soc., 123, pp. 2446-2447
Selenko, P., Wagner, G., (2007) J. Struct. Biol., 158, pp. 244-253
Diana, D., Smaldone, G., De Antonellis, P., Pirone, L., Carotenuto, M., Alonzi, A., Di Gaetano, S., Fattorusso, R., (2013) Chem. Eur. J., 19, pp. 12217-12220
Mayer, M., Meyer, B., (2001) J. Am. Chem. Soc., 123, pp. 6108-6117
Clore, G.M., Gronenborn, A.M., (1982) J. Magn. Reson., 48, pp. 402-417
Claasen, B., Axmann, M., Meinecke, R., Meyer, B., (2005) J. Am. Chem. Soc., 127, pp. 916-919
Potenza, D., Vasile, F., Belvisi, L., Civera, M., Araldi, E.M.V., (2011) Chem Bio Chem, 12, pp. 695-699
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Waltenberger, J., Claesson-Welsh, L., Siegbahnll, A., Shibuya, M., Heldin, C.H., (1994) J. Biol. Chem., 269, pp. 26988-26995
Selenko, P., Serber, Z., Gadea, B., Ruderman, J., Wagner, G., (2006) Proc. Natl. Acad. Sci. USA, 103, pp. 11904-11909
Crowley, P.B., Chow, E., Papkovskaia, T., (2011) Chem Bio Chem, 12, pp. 1043-1048
D'Silva, L., Ozdowy, P., Krajewski, M., Rothweiler, U., Singh, M., Holak, T.A., (2005) J. Am. Chem. Soc., 127, pp. 13220-13226
Grinstead, J.S., Schuman, J.T., Campbell, A.P., (2003) Biochemistry, 42, pp. 14293-14305
Peto, H., Scott, K., Sunde, M., Broadhurst, R.W., (2004) J. Struct. Biol., 148, pp. 214-225
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D'Andrea, L. D., Laccarino, G., Fattorusso, R., Sorriento, D., Carannante, C., Capasso, D., Trimarco, B., Pedone, C., (2005) Proc. Natl. Acad. Sci. USA, 102, pp. 14215-14220
Clore, G. M., Gronenborn, A. M., (1982) J. Magn. Reson., 48, pp. 402-417
Crowley, P. B., Chow, E., Papkovskaia, T., (2011) Chem Bio Chem, 12, pp. 1043-1048
Grinstead, J. S., Schuman, J. T., Campbell, A. P., (2003) Biochemistry, 42, pp. 14293-14305
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2015 Jan 2; 21(1): 91-95.
Export to Esporta in BibTeX Export to Esporta in EndNote
Paper type Tipo di articolo: Journal Article, Research Support, Non-U. S. Gov'T,
Impact factor: 5.771, 5-year impact factor Impact factor a 5 anni: 5.572
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84920579931&partnerID=40&md5=3afe27390297fb1e8630bb85206fc464
Keywords Parole chiave: 15n Labelled Peptides, Living Cells, Nmr Spectroscopy, Peptide-Protein Interaction, Vegf Receptors, Cell Engineering, Cytology, Isotopes, Nuclear Magnetic Resonance Spectroscopy, Binding Surface, Functional Interaction, Receptor Targeting, Relaxation Measurements, Vascular Endothelial Growth Factor Receptor, Endothelial Cells, Nitrogen Isotopes, Agonists, Animals, Cell Line, Chemistry, Genetics, Metabolism, Biomolecular, Protein Interaction Domains And Motifs, Protein Structure, Secondary, Swine,
Affiliations Affiliazioni:
*** IBB - CNR ***
Dipartimento di Scienze e Tecnologie Ambientali, Biologiche e Farmaceutiche, Seconda Universitädegli Studi Napoli, via Vivaldi 46Caserta, Italy
Istituto di Biostrutture e Bioimmagini C.N.R., via Mezzocannone 16Napoli, Italy
Dipartimento di Farmacia, Università Degli Studi di Napoli Federico II, via Mezzocannone 16Napoli, Italy
References Riferimenti:
Carmeliet, P., (2005) Nature, 438, pp. 932-93
Ferrara, N., Gerber, H.P., Le Couter, J., (2003) Nat. Med., 9, pp. 669-676
Ferrara, N., (2000) Curr. Opin. Biotechnol., 11, pp. 617-624
Ferrara, N., Kerbel, R.S., (2005) Nature, 438, pp. 967-974
Maglione, D., Guerriero, V., Viglietto, G., Delli-Bovi, P., Persico, M.G., (1991) Proc. Natl. Acad. Sci. USA, 88, pp. 9267-9271
Fischer, Mazzone, M., Jonckx, B., Carmeliet, P., (2008) Nat. Rev. Cancer, 8, pp. 942-956
Cao, Y., (2009) Sci. Signaling, 2, p. re12
Wiesmann, C., Fuh, G., Christinger, H.W., Eigenbro, C., Wells, J.A., De Vos, A.M., (1998) Biochemistry, 37, pp. 17765-17772
Christinger, H.W., Fuh, G., De Vos, A.M., Wiesmann, C., (2004) J. Biol. Chem., 279, pp. 10382-10388
D'Andrea, L.D., Laccarino, G., Fattorusso, R., Sorriento, D., Carannante, C., Capasso, D., Trimarco, B., Pedone, C., (2005) Proc. Natl. Acad. Sci. USA, 102, pp. 14215-14220
Diana, D., Ziaco, B., Colombo, G., Scarabelli, G., Romanelli, A., Pedone, C., Fattorusso, R., D'Andrea, L.D., (2008) Chem. Eur. J., 14, pp. 4164-4166
Diana, D., Basile, A., De Rosa, L., Di Stasi, R., Auriemma, S., Arra, C., Pedone, C., D'Andrea, L.D., (2011) J. Biol. Chem., 286, pp. 41680-41691
Basile, A., Del Gatto, A., Diana, D., Di Stasi, R., Falco, A., Festa, M., Rosati, A., D'Andrea, L.D., (2011) J. Med. Chem., 54, pp. 1391-1400
De Rosa, L., Diana, D., Basile, A., Russomanno, A., Isernia, C., Turco, M.C., Fattorusso, R., D'Andrea, L.D., (2014) Eur. J. Med. Chem., 73, pp. 210-216
Ito, Y., Selenko, P., (2010) Curr. Opin. Struct. Biol., 20, pp. 640-648
Reckel, S., Lohr, F., Dotsch, V., (2005) Chem Bio Chem, 6, pp. 1601-1606
Serber, Z., Keatinge-Clay, A.T., Kelly, A.E., Miller, S.M., Dotsch, V., (2001) J. Am. Chem. Soc., 123, pp. 2446-2447
Selenko, P., Wagner, G., (2007) J. Struct. Biol., 158, pp. 244-253
Diana, D., Smaldone, G., De Antonellis, P., Pirone, L., Carotenuto, M., Alonzi, A., Di Gaetano, S., Fattorusso, R., (2013) Chem. Eur. J., 19, pp. 12217-12220
Mayer, M., Meyer, B., (2001) J. Am. Chem. Soc., 123, pp. 6108-6117
Clore, G.M., Gronenborn, A.M., (1982) J. Magn. Reson., 48, pp. 402-417
Claasen, B., Axmann, M., Meinecke, R., Meyer, B., (2005) J. Am. Chem. Soc., 127, pp. 916-919
Potenza, D., Vasile, F., Belvisi, L., Civera, M., Araldi, E.M.V., (2011) Chem Bio Chem, 12, pp. 695-699
Airoldi, C., Giovannardi, S., La Ferla, B., Barbero, J.J., Nicotra, F., (2011) Chem. Eur. J., 17, pp. 13395-13399
Waltenberger, J., Claesson-Welsh, L., Siegbahnll, A., Shibuya, M., Heldin, C.H., (1994) J. Biol. Chem., 269, pp. 26988-26995
Selenko, P., Serber, Z., Gadea, B., Ruderman, J., Wagner, G., (2006) Proc. Natl. Acad. Sci. USA, 103, pp. 11904-11909
Crowley, P.B., Chow, E., Papkovskaia, T., (2011) Chem Bio Chem, 12, pp. 1043-1048
D'Silva, L., Ozdowy, P., Krajewski, M., Rothweiler, U., Singh, M., Holak, T.A., (2005) J. Am. Chem. Soc., 127, pp. 13220-13226
Grinstead, J.S., Schuman, J.T., Campbell, A.P., (2003) Biochemistry, 42, pp. 14293-14305
Peto, H., Scott, K., Sunde, M., Broadhurst, R.W., (2004) J. Struct. Biol., 148, pp. 214-225
Sakakibara, D., Sasaki, A., Ikeya, T., Hamatsu, J., Hanashima, T., Mishima, M., Yoshimasu, M., Ito, Y., (2009) Nat. Struct. Mol. Biol., 458, pp. 102-105
D'Andrea, L. D., Laccarino, G., Fattorusso, R., Sorriento, D., Carannante, C., Capasso, D., Trimarco, B., Pedone, C., (2005) Proc. Natl. Acad. Sci. USA, 102, pp. 14215-14220
Clore, G. M., Gronenborn, A. M., (1982) J. Magn. Reson., 48, pp. 402-417
Crowley, P. B., Chow, E., Papkovskaia, T., (2011) Chem Bio Chem, 12, pp. 1043-1048
Grinstead, J. S., Schuman, J. T., Campbell, A. P., (2003) Biochemistry, 42, pp. 14293-14305
Functional Binding Surface Of A Beta-Hairpin Vegf Receptor Targeting Peptide Determined By Nmr Spectroscopy In Living Cells
In this study, the functional interaction of HPLW peptide with VEGFR2 (Vascular Endothelial Growth Factor Receptor 2) was determined by using fast (15)N-edited NMR spectroscopic experiments. To this aim, (15)N uniformly labelled HPLW has been added to Porcine Aortic Endothelial Cells. The acquisition of isotope-edited NMR spectroscopic experiments, including (15)N relaxation measurements, allowed a precise characterization of the in-cell HPLW epitope recognized by VEGFR2. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
In this study, the functional interaction of HPLW peptide with VEGFR2 (Vascular Endothelial Growth Factor Receptor 2) was determined by using fast (15)N-edited NMR spectroscopic experiments. To this aim, (15)N uniformly labelled HPLW has been added to Porcine Aortic Endothelial Cells. The acquisition of isotope-edited NMR spectroscopic experiments, including (15)N relaxation measurements, allowed a precise characterization of the in-cell HPLW epitope recognized by VEGFR2. © 2015 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.
Functional Binding Surface Of A Beta-Hairpin Vegf Receptor Targeting Peptide Determined By Nmr Spectroscopy In Living Cells
Functional Binding Surface Of A Beta-Hairpin Vegf Receptor Targeting Peptide Determined By Nmr Spectroscopy In Living Cells
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Farina B, Pirone L, Russo L, Viparelli F, Doti N, Pedone C, Pedone E, Fattorusso R
* NMR backbone dynamics studies of human PED/PEA-15 outline protein functional sites (621 visite)
Febs J (ISSN: 1742-4658, 1742-464x, 1742-4658electronic), 2010 Oct; 277(20): 4229-4240.
Impact Factor: 3.129
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Diana D, Ziaco B, Scarabelli G, Pedone C, Colombo G, D'Andrea LD, Fattorusso R
* Structural analysis of a helical peptide unfolding pathway (404 visite)
Chemistry (ISSN: 1521-3765, 0947-6539, 1521-3765electronic), 2010 May 10; 16(18): 5400-5407.
Impact Factor: 5.476
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Abbate M, Casella G, Fiore T, Grasso G, Pellerito C, Scopelliti M, Spinella A, Pellerito L
* Structural characterization of triorganotin(IV) complexes with sodium fusidate and DFT calculations (332 visite)
J Organomet Chem (ISSN: 0022-328x), 2010 May 1; 695(9): 1405-1413.
Impact Factor: 2.205
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Puglisi A, Rizzarelli E, Vecchio G, Iacovino R, Benedetti E, Pedone C, Saviano M
* Crystal And Molecular Structure Of Beta-Cyclodextrins Functionalized With The Anti-Inflammatory Drug Etodolac (387 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2009 Dec; 91(12): 1227-1235.
Impact Factor: 2.605
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Kaczmarek K, Farina B, Zubrzak P, Jankowski S, Zimecki M, Suder P, Benedetti E, Fattorusso R, Saviano M, Zabrocki J
* Synthesis, conformational analysis and immunological activity of β3Phe-substituted Cyclolinopeptide A analogues (440 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 166-174.
Impact Factor: 1.807
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Diana D, Ziaco B, Colombo G, Scarabelli G, Romanelli A, Fedone C, Fattorusso R, D'Andrea LD
* Structural determinants of the unusual helix stability of a de novo engineered vascular endothelial growth factor (VEGF) mimicking peptide (405 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2008; 14(14): 4164-4166.
Impact Factor: 5.454
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Malgieri G, Russo L, Esposito S, Baglivo I, Zaccaro L, Pedone EM, Di Blasio B, Isernia C, Pedone PV, Fattorusso R
* The Prokaryotic Cys2his2 Zinc Finger Domain Adopts A Novel Fold As Revealed By The Solution Structure Of Agrobacterium Tumefaciens Ros Dna Binding Domain (346 visite)
P Natl Acad Sci Usa (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2007 Oct 30; 104(44): 17341-17346.
Impact Factor: 9.598
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De Pinto V, Tomasello F, Messina A, Guarino F, Benz R, La Mendola D, Magrì A, Milardi D, Pappalardo G
* Determination of the conformation of the human VDAC1 N-terminal peptide, a protein moiety essential for the functional properties of the pore (408 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2007 May 7; 8(7): 744-756.
Impact Factor: 3.446
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Milardi D, Arnesano F, Grasso G, Magrì A, Tabbì G, Scintilla S, Natile G, Rizzarelli E
* Ubiquitin stability and the Lys63-linked polyubiquitination site are compromised on copper binding (292 visite)
Angew Chem Int Ed (ISSN: 1433-7851, 1521-3773electronic), 2007; 46(42): 7993-7995.
Impact Factor: 10.031
Dettagli Esporta in BibTeX Esporta in EndNote
De Capua A, Goodman M, Amino Y, Saviano M, Benedetti E
* Conformation analysis of aspartame-based sweeteners by NMR spectroscopy, molecular dynamics simulations, and X-ray diffraction studies (595 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2006 Feb; 7(2): 377-387.
Impact Factor: 4.1
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D'Andrea LD, Iaccarino G, Fattorusso R, Sorriento D, Carannante C, Capasso D, Trimarco B, Pedone C
* Targeting angiogenesis: Structural characterization and biological properties of a de novo engineered VEGF mimicking peptide (483 visite)
P Natl Acad Sci Usa (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2005 Oct 4; 102(40): 14215-14220.
Impact Factor: 10.231
Dettagli Esporta in BibTeX Esporta in EndNote
Falcigno L, Oliva R, D'Auria G, Maletta M, Dettin M, Pasquato A, Di Bello C, Paolillo L
* Structural investigation of the HIV-1 envelope glycoprotein gp160 cleavage site 3: Role of site-specific mutations (335 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2004 Dec 3; 5(12): 1653-1661.
Impact Factor: 3.474
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Lombardi A, Nastri F, Marasco D, Maglio O, De Sanctis G, Sinibaldi F, Santucci R, Coletta M, Pavone V
* Design of a new mimochrome with unique topology (453 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2003 Nov 21; 9(22): 5643-5654.
Impact Factor: 4.353
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Oliva R, Falcigno L, D'Auria G, Dettin M, Scarinci C, Pasquato A, Di Bello C, Paolillo L
* Structural investigation of the HIV-1 envelope glycoprotein gp160 cleavage site (347 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2003 Sep 4; 4(8): 727-733.
Impact Factor: 3.992
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Oliva R, Falcigno L, D'Auria G, Dettin M, Scarinci C, Pasquato A, Di Bello C, Paolillo L
* Structural investigation of the HIV-1 envelope glycoprotein gp160 cleavage site, 2: relevance of an N-terminal helix (293 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2003 Aug 4; 4(8): 727-733.
Impact Factor: 2.92
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Isernia C, Bucci E, Leone M, Zaccaro L, Di Lello P, Digilio G, Esposito S, Saviano M, Di Blasio B, Pedone C, Pedone PV, Fattorusso R
* NMR structure of the single QALGGH zinc finger domain from the Arabidopsis thaliana SUPERMAN protein (384 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2003 Mar 3; 4(2-3): 171-180.
Impact Factor: 3.992
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D’Andrea LD, Fattorusso R, Carannante C, Pedone C
* Targeting VEGF Receptors Using Designed Polypeptide (230 visite)
Peptides 2002, 2002; ConferenceBook: 454-455.
Impact Factor: 0
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Saviano G, Rossi F, Benedetti E, Pedone C, Mierke DF, Maione A, Zanotti G, Tancredi T, Saviano M
* Structural consequences of metal complexation of cyclo[Pro-Phe-Phe-Ala-Xaa]2 decapeptides (401 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2001 Mar 16; 7(6): 1176-1183.
Impact Factor: 4.614
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Zanotti G, Falcigno L, Saviano M, D'Auria G, Bruno BM, Campanile T, Paolillo L
* Solid state and solution conformation of [Ala7]-phalloidin: A synthetic phallotoxin analogue (406 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2001; 7(7): 1479-1485.
Impact Factor: 4.614
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Impellizzeri G, Pappalardo G, Purrello R, Rizzarelli E, Santoro AM
Synthesis, spectroscopic characterisation, and metal ion interaction of a new α-helical peptide (440 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 1998; 4(9): 1791-1798.
Impact Factor: 5.153
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D'Auria G, Maglio O, Nastri F, Lombardi A, Mazzeo M, Morelli G, Paolillo L, Pedone C, Pavone V
Hemoprotein models based on a covalent helix-heme-helix sandwich: 2. Structural characterization of Co(III) mimochrome I Δ and Λ isomers (387 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 1997; 3(3): 350-362.
Impact Factor: 4.828
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47 Records (46 escludendo Abstract e Conferenze).
Impact factor totale: 192.369 (192.369 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 192.312 (192.312 escludendo Abstract e Conferenze).
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Monti A, Bruckmann C, Blasi F, Ruvo M, Vitagliano L, Doti N
* Amyloid-like Prep1 peptides exhibit reversible blue-green-red fluorescence in vitro and in living cells (11 visite)
Chem Commun (ISSN: 1359-7345linking), 2021 Apr 18; 57(30): 3720-3723.
Impact Factor: 5.996
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Vincenzi M, Mercurio FA, Leone M
* NMR spectroscopy in the conformational analysis of peptides: an overview (62 visite)
Curr Med Chem (ISSN: 0929-8673linking), 2021; 28(14): 2729-2782.
Impact Factor: 4.184
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Riccardi C, Capasso D, Coppola A, Platella C, Montesarchio D, Di Gaetano S, Roviello GN, Musumeci D
* Synthesis, Antiproliferative Activity, and DNA Binding Studies of Nucleoamino Acid-Containing Pt(II) Complexes (122 visite)
Pharmaceuticals (ISSN: 1424-8247linking), 2020 Sep 30; 13(10): 284-284.
Impact Factor: 4.421
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Mercurio FA, Di Natale C, Pirone L, Vincenzi M, Marasco D, De Luca S, Pedone EM, Leone M
* Exploring the ability of cyclic peptides to target SAM domains: a computational and experimental study (237 visite)
Chembiochem (ISSN: 1439-4227linking, 1439-7633), 2020 Mar 2; 21(5): 702-711.
Impact Factor: 2.641
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Riccardi C, Capasso D, Rozza GM, Platella C, Montesarchio D, Di Gaetano S, Marzo T, Pratesi A, Messori L, Roviello GN, Musumeci D
* Synthesis, DNA binding studies, and antiproliferative activity of novel Pt(II)- complexes with an L-alanyl-based ligand (232 visite)
J Inorg Biochem (ISSN: 0162-0134linking), 2020 Feb; 203: 110868-110868.
Impact Factor: 3.224
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Farina B, Del Gatto A, Comegna D, Di Gaetano S, Capasso D, Isernia C, Saviano M, Fattorusso R, Zaccaro L, Russo L
* Conformational studies of RGDechi peptide by natural-abundance NMR spectroscopy (230 visite)
J Pept Sci (ISSN: 1075-2617linking, 1099-1387electronic), 2019 May; 25(5): e3166-e3166.
Impact Factor: 1.807
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Caporale A, Martin AD, Capasso D, Foca G, Sandomenico A, D'Andrea LD, Grieco P, Ruvo M, Doti N
* Short PlGF-derived peptides bind VEGFR-1 and VEGFR-2 in vitro and on the surface of endothelial cells (262 visite)
J Pept Sci (ISSN: 1075-2617linking, 1099-1387electronic), 2019 May; 25 (5 ): e3146-e3146.
Impact Factor: 1.807
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Grage SL, Kara S, Bordessa A, Doan V, Rizzolo F, Putzu M, Kubar T, Papini AM, Chaume G, Brigaud T, Afonin S, Ulrich AS
* Orthogonal (19) F-Labeling for Solid-State NMR Spectroscopy Reveals the Conformation and Orientation of Short Peptaibols in Membranes (318 visite)
Chemistry (ISSN: 1521-3765electronic, 0947-6539linking), 2018 Jan 11; N/D: N/D-N/D.
Impact Factor: 5.476
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Siepia M, Oliva R, Petraccone L, Del Vecchio P, Ricca E, Isticato R, Lanzilli M, Maglio O, Lombardi A, Leone L, Notomista E, Donadio G
* Fluorescent peptide dH3w: sensor for environmental and living cells monitoring of mercury (II) (149 visite)
Plos One, 2018; N/D: N/D-N/D.
Impact Factor: 2.766
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Di Stasi R, Diana D, Capasso D, Di Gaetano S, De Rosa L, Celentano V, Isernia C, Fattorusso R, D'Andrea LD
* VEGFR Recognition Interface of a Proangiogenic VEGF-Mimetic Peptide Determined In Vitro and in the Presence of Endothelial Cells by NMR Spectroscopy (301 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2018; 24(44): 11461-11466.
Impact Factor: 5.16
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Calvanese L, Foca A, Sandomenico A, Foca G, Caporale A, Doti N, Iaccarino E, Leonardi A, D'Auria G, Ruvo M, Falcigno L
* Structural insights into the interaction of a monoclonal antibody and Nodal peptides by STD-NMR spectroscopy (471 visite)
Bioorg Med Chem (ISSN: 0968-0896, 1464-3391, 0968-0896linking), 2017 Dec 15; 25(24): 6589-6596.
Impact Factor: 2.881
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Calvanese L, Caporale A, Focà G, Iaccarino E, Sandomenico A, Doti N, Apicella I, Incisivo GM, De Falco S, Falcigno L, D’auria G, Ruvo M
* Targeting VEGF receptors with non-neutralizing cyclopeptides for imaging applications (386 visite)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2017 Dec 2; 50(2): 321-329.
Impact Factor: 2.906
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Cavallari E, Carrera C, Aime S, Reineri F
* (13) C MR Hyperpolarization of Lactate by Using ParaHydrogen and Metabolic Transformation in Vitro (236 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2017 Jan 23; 23(5): 1200-1204.
Impact Factor: 5.16
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Celentano V, Diana D, Di Salvo C, De Rosa L, Romanelli A, Fattorusso R, D'Andrea LD
* 1, 2, 3-Triazole Bridge as Conformational Constrain in beta-Hairpin Peptides: Analysis of Hydrogen-Bonded Positions (402 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2016 Apr 11; 22(16): 5534-5537.
Impact Factor: 5.317
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Farina B, De Paola I, Russo L, Capasso D, Liguoro A, Gatto AD, Saviano M, Pedone PV, Di Gaetano S, Malgieri G, Zaccaro L, Fattorusso R
* A Combined NMR and Computational Approach to Determine the RGDechi-hCit-alphav beta3 Integrin Recognition Mode in Isolated Cell Membranes (538 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2016 Jan 11; 22(2): 681-693.
Impact Factor: 5.317
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Bottini A, Wu B, Barile E, De SK, Leone M, Pellecchia M
* High-Throughput Screening (HTS) by NMR Guided Identification of Novel Agents Targeting the Protein Docking Domain of YopH (380 visite)
Chemmedchem (ISSN: 1860-7179, 1860-7187, 1860-7179linking), 2015 Nov 23; 11(8): 919-927.
Impact Factor: 2.98
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Smaldone G, Diana D, Pollegioni L, Di Gaetano S, Fattorusso R, Pedone E
* Insight into conformational modification of alpha-synuclein in the presence of neuronal whole cells and of their isolated membranes (364 visite)
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468), 2015 Feb 18; 589(7): 798-804.
Impact Factor: 3.519
Dettagli Esporta in BibTeX Esporta in EndNote
Mercurio FA, Di Natale C, Pirone L, Scognamiglio PL, Marasco D, Pedone EM, Saviano M, Leone M
* Peptide Fragments of Odin-Sam1: Conformational Analysis and Interaction Studies with EphA2-Sam (434 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-4227linking), 2015; 16(11): 1629-1636.
Impact Factor: 2.85
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Vitale RM, Zaccaro L, Di Blasio B, Fattorusso R, Isernia C, Amodeo P, Pedone C, Saviano M
* Conformational features of human melanin-concentrating hormone: an NMR and computational analysis (414 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-4227linking), 2014 Sep 17; 4(1): 73-81.
Impact Factor: 3.088
Dettagli Esporta in BibTeX Esporta in EndNote
De Rosa L, Diana D, Basile A, Russomanno A, Isernia C, Turco MC, Fattorusso R, D'Andrea LD
* Design, Structural And Biological Characterization Of A Vegf Inhibitor Beta-Hairpin-Constrained Peptide (477 visite)
Eur J Med Chem (ISSN: 0223-5234, 1768-3254, 0223-5234linking), 2014; 73: 210-216.
Impact Factor: 3.447
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Diana D, Smaldone G, De Antonellis P, Pirone L, Carotenuto M, Alonzi A, Di Gaetano S, Zollo M, Pedone E, Fattorusso R
* Mapping Functional Interaction Sites of Human Prune C-Terminal Domain by NMR Spectroscopy in Human Cell Lysates (322 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2013 Sep 9; 19(37): 12217-12220.
Impact Factor: 5.696
Dettagli Esporta in BibTeX Esporta in EndNote
Farina B, Doti N, Pirone L, Malgieri G, Pedone E, Ruvo M, Fattorusso R
* Molecular basis of the PED/PEA15 interaction with the C-terminal fragment of phospholipase D1 revealed by NMR spectroscopy (433 visite)
Bba-Gen Subjects (ISSN: 1570-9639, 0006-3002, 0925-4439), 2013 Sep; 1834(8): 1572-1580.
Impact Factor: 3.191
Dettagli Esporta in BibTeX Esporta in EndNote
Mercurio FA, Marasco D, Pirone L, Scognamiglio PL, Pedone E, Pellecchia M, Leone M
* Heterotypic Sam-Sam Association Between Odin-Sam1 And Arap3-Sam: Binding Affinity And Structural Insights (315 visite)
Chembiochem (ISSN: 1439-4227, 1439-9422, 1439-7633), 2013 Jan 2; 14(1): 100-106.
Impact Factor: 2.92
Dettagli Esporta in BibTeX Esporta in EndNote
Malgieri G, Zaccaro L, Leone M, Bucci E, Esposito S, Baglivo I, Del Gatto A, Russo L, Scandurra R, Pedone PV, Fattorusso R, Isernia C
* Zinc to Cadmium Replacement in the A. thaliana SUPERMAN Cys(2)His(2) Zinc Finger Induces Structural Rearrangements of Typical DNA Base Determinant Positions (381 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2011 Nov; 95(11): 801-810.
Impact Factor: 2.87
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Cucinotta V, Giuffrida A, Grasso G, MacCarrone G, Mazzaglia A, Messina M, Vecchio G
* Diaminotrehalose-capped β-cyclodextrin, a new member of hemispherodextrins: Synthesis, thermodynamic and spectroscopic characterization and its exploitation in chiral electrokinetic chromatography (355 visite)
J Sep Sci (ISSN: 1615-9306), 2011 Jan; 34(1): 70-76.
Impact Factor: 2.733
Dettagli Esporta in BibTeX Esporta in EndNote
Verardi R, Traaseth NJ, Shi L, Porcelli F, Monfregola L, De Luca S, Amodeo P, Veglia G, Scaloni A
* Probing membrane topology of the antimicrobial peptide distinctin by solid-state NMR spectroscopy in zwitterionic and charged lipid bilayers (461 visite)
Bba-Gen Subjects (ISSN: 0005-2736, 0006-3002, 0925-4439), 2011 Jan; 1808(1): 34-40.
Impact Factor: 3.99
Dettagli Esporta in BibTeX Esporta in EndNote
Farina B, Pirone L, Russo L, Viparelli F, Doti N, Pedone C, Pedone E, Fattorusso R
* NMR backbone dynamics studies of human PED/PEA-15 outline protein functional sites (621 visite)
Febs J (ISSN: 1742-4658, 1742-464x, 1742-4658electronic), 2010 Oct; 277(20): 4229-4240.
Impact Factor: 3.129
Dettagli Esporta in BibTeX Esporta in EndNote
Diana D, Ziaco B, Scarabelli G, Pedone C, Colombo G, D'Andrea LD, Fattorusso R
* Structural analysis of a helical peptide unfolding pathway (404 visite)
Chemistry (ISSN: 1521-3765, 0947-6539, 1521-3765electronic), 2010 May 10; 16(18): 5400-5407.
Impact Factor: 5.476
Dettagli Esporta in BibTeX Esporta in EndNote
Abbate M, Casella G, Fiore T, Grasso G, Pellerito C, Scopelliti M, Spinella A, Pellerito L
* Structural characterization of triorganotin(IV) complexes with sodium fusidate and DFT calculations (332 visite)
J Organomet Chem (ISSN: 0022-328x), 2010 May 1; 695(9): 1405-1413.
Impact Factor: 2.205
Dettagli Esporta in BibTeX Esporta in EndNote
Puglisi A, Rizzarelli E, Vecchio G, Iacovino R, Benedetti E, Pedone C, Saviano M
* Crystal And Molecular Structure Of Beta-Cyclodextrins Functionalized With The Anti-Inflammatory Drug Etodolac (387 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2009 Dec; 91(12): 1227-1235.
Impact Factor: 2.605
Dettagli Esporta in BibTeX Esporta in EndNote
Kaczmarek K, Farina B, Zubrzak P, Jankowski S, Zimecki M, Suder P, Benedetti E, Fattorusso R, Saviano M, Zabrocki J
* Synthesis, conformational analysis and immunological activity of β3Phe-substituted Cyclolinopeptide A analogues (440 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 166-174.
Impact Factor: 1.807
Dettagli Esporta in BibTeX Esporta in EndNote
Diana D, Ziaco B, Colombo G, Scarabelli G, Romanelli A, Fedone C, Fattorusso R, D'Andrea LD
* Structural determinants of the unusual helix stability of a de novo engineered vascular endothelial growth factor (VEGF) mimicking peptide (405 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2008; 14(14): 4164-4166.
Impact Factor: 5.454
Dettagli Esporta in BibTeX Esporta in EndNote
Malgieri G, Russo L, Esposito S, Baglivo I, Zaccaro L, Pedone EM, Di Blasio B, Isernia C, Pedone PV, Fattorusso R
* The Prokaryotic Cys2his2 Zinc Finger Domain Adopts A Novel Fold As Revealed By The Solution Structure Of Agrobacterium Tumefaciens Ros Dna Binding Domain (346 visite)
P Natl Acad Sci Usa (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2007 Oct 30; 104(44): 17341-17346.
Impact Factor: 9.598
Dettagli Esporta in BibTeX Esporta in EndNote
De Pinto V, Tomasello F, Messina A, Guarino F, Benz R, La Mendola D, Magrì A, Milardi D, Pappalardo G
* Determination of the conformation of the human VDAC1 N-terminal peptide, a protein moiety essential for the functional properties of the pore (408 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2007 May 7; 8(7): 744-756.
Impact Factor: 3.446
Dettagli Esporta in BibTeX Esporta in EndNote
Milardi D, Arnesano F, Grasso G, Magrì A, Tabbì G, Scintilla S, Natile G, Rizzarelli E
* Ubiquitin stability and the Lys63-linked polyubiquitination site are compromised on copper binding (292 visite)
Angew Chem Int Ed (ISSN: 1433-7851, 1521-3773electronic), 2007; 46(42): 7993-7995.
Impact Factor: 10.031
Dettagli Esporta in BibTeX Esporta in EndNote
De Capua A, Goodman M, Amino Y, Saviano M, Benedetti E
* Conformation analysis of aspartame-based sweeteners by NMR spectroscopy, molecular dynamics simulations, and X-ray diffraction studies (595 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2006 Feb; 7(2): 377-387.
Impact Factor: 4.1
Dettagli Esporta in BibTeX Esporta in EndNote
D'Andrea LD, Iaccarino G, Fattorusso R, Sorriento D, Carannante C, Capasso D, Trimarco B, Pedone C
* Targeting angiogenesis: Structural characterization and biological properties of a de novo engineered VEGF mimicking peptide (483 visite)
P Natl Acad Sci Usa (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2005 Oct 4; 102(40): 14215-14220.
Impact Factor: 10.231
Dettagli Esporta in BibTeX Esporta in EndNote
Falcigno L, Oliva R, D'Auria G, Maletta M, Dettin M, Pasquato A, Di Bello C, Paolillo L
* Structural investigation of the HIV-1 envelope glycoprotein gp160 cleavage site 3: Role of site-specific mutations (335 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2004 Dec 3; 5(12): 1653-1661.
Impact Factor: 3.474
Dettagli Esporta in BibTeX Esporta in EndNote
Lombardi A, Nastri F, Marasco D, Maglio O, De Sanctis G, Sinibaldi F, Santucci R, Coletta M, Pavone V
* Design of a new mimochrome with unique topology (453 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2003 Nov 21; 9(22): 5643-5654.
Impact Factor: 4.353
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Oliva R, Falcigno L, D'Auria G, Dettin M, Scarinci C, Pasquato A, Di Bello C, Paolillo L
* Structural investigation of the HIV-1 envelope glycoprotein gp160 cleavage site (347 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2003 Sep 4; 4(8): 727-733.
Impact Factor: 3.992
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Oliva R, Falcigno L, D'Auria G, Dettin M, Scarinci C, Pasquato A, Di Bello C, Paolillo L
* Structural investigation of the HIV-1 envelope glycoprotein gp160 cleavage site, 2: relevance of an N-terminal helix (293 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2003 Aug 4; 4(8): 727-733.
Impact Factor: 2.92
Dettagli Esporta in BibTeX Esporta in EndNote
Isernia C, Bucci E, Leone M, Zaccaro L, Di Lello P, Digilio G, Esposito S, Saviano M, Di Blasio B, Pedone C, Pedone PV, Fattorusso R
* NMR structure of the single QALGGH zinc finger domain from the Arabidopsis thaliana SUPERMAN protein (384 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2003 Mar 3; 4(2-3): 171-180.
Impact Factor: 3.992
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D’Andrea LD, Fattorusso R, Carannante C, Pedone C
* Targeting VEGF Receptors Using Designed Polypeptide (230 visite)
Peptides 2002, 2002; ConferenceBook: 454-455.
Impact Factor: 0
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Saviano G, Rossi F, Benedetti E, Pedone C, Mierke DF, Maione A, Zanotti G, Tancredi T, Saviano M
* Structural consequences of metal complexation of cyclo[Pro-Phe-Phe-Ala-Xaa]2 decapeptides (401 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2001 Mar 16; 7(6): 1176-1183.
Impact Factor: 4.614
Dettagli Esporta in BibTeX Esporta in EndNote
Zanotti G, Falcigno L, Saviano M, D'Auria G, Bruno BM, Campanile T, Paolillo L
* Solid state and solution conformation of [Ala7]-phalloidin: A synthetic phallotoxin analogue (406 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2001; 7(7): 1479-1485.
Impact Factor: 4.614
Dettagli Esporta in BibTeX Esporta in EndNote
Impellizzeri G, Pappalardo G, Purrello R, Rizzarelli E, Santoro AM
Synthesis, spectroscopic characterisation, and metal ion interaction of a new α-helical peptide (440 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 1998; 4(9): 1791-1798.
Impact Factor: 5.153
Dettagli Esporta in BibTeX Esporta in EndNote
D'Auria G, Maglio O, Nastri F, Lombardi A, Mazzeo M, Morelli G, Paolillo L, Pedone C, Pavone V
Hemoprotein models based on a covalent helix-heme-helix sandwich: 2. Structural characterization of Co(III) mimochrome I Δ and Λ isomers (387 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 1997; 3(3): 350-362.
Impact Factor: 4.828
Dettagli Esporta in BibTeX Esporta in EndNote
47 Records (46 escludendo Abstract e Conferenze).
Impact factor totale: 192.369 (192.369 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 192.312 (192.312 escludendo Abstract e Conferenze).
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