Structural and binding properties of the PASTA domain of PonA2, a key penicillin binding protein from Mycobacterium tuberculosis (449 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2014 Jul; 101(7): 712-719.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 2.385, 5-year impact factor: 2.498
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84898955995&partnerID=40&md5=e09d6c40b41e0fa7eb75d7512c6a52b9
Keywords: Binding, Structure, Tuberculosis, Antibiotics, Polymers, Proteins, Structure (composition), Antibiotic Binding, Binding Properties, Mycobacterium Tuberculosis, Penicillin-Binding Proteins, Solution Structures, Structural Similarity, Binding Energy, Beta Lactam, Penicillin Binding Protein, Peptidoglycan, Pona2 Protein, Unclassified Drug, Alpha Helix, Article, Carboxy Terminal Sequence, Centrifugation, Complex Formation, Controlled Study, Dormancy, Enzyme Active Site, Heteronuclear Nuclear Magnetic Resonance, Heteronuclear Single Quantum Coherence, Isothermal Titration Calorimetry, Ligand Binding, Nonhuman, Nuclear Overhauser Effect, Pasta Domain, Protein Binding, Protein Conformation, Protein Domain, Protein Expression, Protein Secondary Structure, Sequence Analysis, Surface Plasmon Resonance, Surface Property,
Affiliations:
*** IBB - CNR ***
CIRPeB, University of Naples Federico II, Naples, Italy
Department of Pharmacy, University of Naples Federico II, via Mezzocannone 16, 80134 Naples, Italy
Institute of Biostructures and Bioimaging-CNR, via Mezzocannone 16, 80134 Naples, Italy
Department of Chemical Sciences, University of Naples Federico II, via Cintia 45, 80126 Naples, Italy
References:
Morandi, M., Sali, M., Manganelli, R., Delogu, G., (2013) J Infect Dev Ctries, 7, pp. 169-18
Ruggiero, A., Marchant, J., Squeglia, F., Makarov, V., De Simone, A., Berisio, R., (2013) J Biomol Struct Dyn, 31, pp. 195-205
Ruggiero, A., De Simone, P., Smaldone, G., Squeglia, F., Berisio, R., (2012) Curr Protein Pept Sci, 13, pp. 756-766
Ruggiero, A., Marasco, D., Squeglia, F., Soldini, S., Pedone, E., Pedone, C., Berisio, R., (2010) Structure, 18, pp. 1184-1190
Ruggiero, A., Tizzano, B., Pedone, E., Pedone, C., Wilmanns, M., Berisio, R., (2009) J Mol Biol, 385, pp. 153-162
Correale, S., Ruggiero, A., Capparelli, R., Pedone, E., Berisio, R., (2013) Acta Crystallogr D Biol Crystallogr, 69, pp. 1697-1706
Sauvage, E., Kerff, F., Terrak, M., Ayala, J. A., Charlier, P., (2008) FEMS Microbiol Rev, 32, pp. 234-258
Mukamolova, G. V., Turapov, O. A., Young, D. I., Kaprelyants, A. S., Kell, D. B., Young, M., (2002) Mol Microbiol, 46, pp. 623-635
Van Gunsteren, W. F., Berendsen, H. J., Hermans, J., Hol, W. G., Postma, J. P., (1983) Proc Natl Acad Sci USA, 80, pp. 4315-4319
Chao, M. C., Kieser, K. J., Minami, S., Mavrici, D., Aldridge, B. B., Fortune, S. M., Alber, T., Rubin, E., (2013) J. PLOS Pathogens, 9, pp. e1003197
Chao, M. C., Rubin, E., (2010) J. Annu Rev Microbiol, 64, pp. 293-311
Sung, M. T., Lai, Y. T., Huang, C. Y., Chou, L. Y., Shih, H. W., Cheng, W. C., Wong, C. H., Ma, C., (2009) Proc Natl Acad Sci USA, 106, pp. 8824-8829
Dessen, A., Mouz, N., Gordon, E., Hopkins, J., Dideberg, O., (2001) J Biol Chem, 276, pp. 45106-45112
Yeats, C., Finn, R. D., Bateman, A., (2002) Trends Biochem Sci, 27, p. 438
Shah, I. M., Laaberki, M. H., Popham, D. L., Dworkin, (2008) J. Cell, 135, pp. 486-496
Squeglia, F., Marchetti, R., Ruggiero, A., Lanzetta, R., Marasco, D., Dworkin, J., Petoukhov, M., Silipo, A., (2011) J Am Chem Soc, 133, pp. 20676-20679
Mir, M., Asong, J., Li, X., Cardot, J., Boons, G. J., Husson, R. N., (2011) PLOS Pathogens, 7, pp. e1002182
Maestro, B., Novakova, L., Hesek, D., Lee, M., Leyva, E., Mobashery, S., Sanz, J. M., Branny, P., (2011) FEBS Lett, 585, pp. 357-363
Vandal, O. H., Pierini, L. M., Schnappinger, D., Nathan, C. F., Ehrt, S., (2008) Nat Med, 14, pp. 849-854
Patru, M. M., Pavelka, Jr. M. S., (2010) J Bacteriol, 192, pp. 3043-3054
Ruggiero, A., Squeglia, F., Marasco, D., Marchetti, R., Molinaro, A., Berisio, R., (2011) Biochem J, 435, pp. 33-41
Gordon, E., Mouz, N., Duee, E., Dideberg, O., (2000) J Mol Biol, 299, pp. 477-485
Hildebrand, A., Remmert, M., Biegert, A., Soding, (2009) J. Proteins, 77 (SUPPL. 9), pp. 128-132
Mathur, A., Shankaracharya, Vidyarthi, A. S., (2012) J Mol Model, 18, pp. 3021-3023
Cheng, T. J., Sung, M. T., Liao, H. Y., Chang, Y. F., Chen, C. W., Huang, C. Y., Chou, L. Y., Cheng, W. C., (2008) Proc Natl Acad Sci USA, 105, pp. 431-436
Hett, E. C., Chao, M. C., Steyn, A. J., Fortune, S. M., Deng, L. L., Rubin, E., (2007) J. Mol Microbiol, 66, pp. 658-668
Rodriguez, R., Chinea, G., Lopez, N., Pons, T., Vriend, G., (1998) Bioinformatics, 14, pp. 523-528
Koradi, R., Billeter, M., Wuthrich, K., (1996) J Mol Graph, 14, pp. 51-55. , 29-32
Poletto, M., Vascotto, C., Scognamiglio, P. L., Lirussi, L., Marasco, D., Tell, G., (2013) Biochem J, 452, pp. 545-557
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2014 Jul; 101(7): 712-719.
Export to BibTeX Export to EndNote
Paper type: Journal Article,
Impact factor: 2.385, 5-year impact factor: 2.498
Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84898955995&partnerID=40&md5=e09d6c40b41e0fa7eb75d7512c6a52b9
Keywords: Binding, Structure, Tuberculosis, Antibiotics, Polymers, Proteins, Structure (composition), Antibiotic Binding, Binding Properties, Mycobacterium Tuberculosis, Penicillin-Binding Proteins, Solution Structures, Structural Similarity, Binding Energy, Beta Lactam, Penicillin Binding Protein, Peptidoglycan, Pona2 Protein, Unclassified Drug, Alpha Helix, Article, Carboxy Terminal Sequence, Centrifugation, Complex Formation, Controlled Study, Dormancy, Enzyme Active Site, Heteronuclear Nuclear Magnetic Resonance, Heteronuclear Single Quantum Coherence, Isothermal Titration Calorimetry, Ligand Binding, Nonhuman, Nuclear Overhauser Effect, Pasta Domain, Protein Binding, Protein Conformation, Protein Domain, Protein Expression, Protein Secondary Structure, Sequence Analysis, Surface Plasmon Resonance, Surface Property,
Affiliations:
*** IBB - CNR ***
CIRPeB, University of Naples Federico II, Naples, Italy
Department of Pharmacy, University of Naples Federico II, via Mezzocannone 16, 80134 Naples, Italy
Institute of Biostructures and Bioimaging-CNR, via Mezzocannone 16, 80134 Naples, Italy
Department of Chemical Sciences, University of Naples Federico II, via Cintia 45, 80126 Naples, Italy
References:
Morandi, M., Sali, M., Manganelli, R., Delogu, G., (2013) J Infect Dev Ctries, 7, pp. 169-18
Ruggiero, A., Marchant, J., Squeglia, F., Makarov, V., De Simone, A., Berisio, R., (2013) J Biomol Struct Dyn, 31, pp. 195-205
Ruggiero, A., De Simone, P., Smaldone, G., Squeglia, F., Berisio, R., (2012) Curr Protein Pept Sci, 13, pp. 756-766
Ruggiero, A., Marasco, D., Squeglia, F., Soldini, S., Pedone, E., Pedone, C., Berisio, R., (2010) Structure, 18, pp. 1184-1190
Ruggiero, A., Tizzano, B., Pedone, E., Pedone, C., Wilmanns, M., Berisio, R., (2009) J Mol Biol, 385, pp. 153-162
Correale, S., Ruggiero, A., Capparelli, R., Pedone, E., Berisio, R., (2013) Acta Crystallogr D Biol Crystallogr, 69, pp. 1697-1706
Sauvage, E., Kerff, F., Terrak, M., Ayala, J. A., Charlier, P., (2008) FEMS Microbiol Rev, 32, pp. 234-258
Mukamolova, G. V., Turapov, O. A., Young, D. I., Kaprelyants, A. S., Kell, D. B., Young, M., (2002) Mol Microbiol, 46, pp. 623-635
Van Gunsteren, W. F., Berendsen, H. J., Hermans, J., Hol, W. G., Postma, J. P., (1983) Proc Natl Acad Sci USA, 80, pp. 4315-4319
Chao, M. C., Kieser, K. J., Minami, S., Mavrici, D., Aldridge, B. B., Fortune, S. M., Alber, T., Rubin, E., (2013) J. PLOS Pathogens, 9, pp. e1003197
Chao, M. C., Rubin, E., (2010) J. Annu Rev Microbiol, 64, pp. 293-311
Sung, M. T., Lai, Y. T., Huang, C. Y., Chou, L. Y., Shih, H. W., Cheng, W. C., Wong, C. H., Ma, C., (2009) Proc Natl Acad Sci USA, 106, pp. 8824-8829
Dessen, A., Mouz, N., Gordon, E., Hopkins, J., Dideberg, O., (2001) J Biol Chem, 276, pp. 45106-45112
Yeats, C., Finn, R. D., Bateman, A., (2002) Trends Biochem Sci, 27, p. 438
Shah, I. M., Laaberki, M. H., Popham, D. L., Dworkin, (2008) J. Cell, 135, pp. 486-496
Squeglia, F., Marchetti, R., Ruggiero, A., Lanzetta, R., Marasco, D., Dworkin, J., Petoukhov, M., Silipo, A., (2011) J Am Chem Soc, 133, pp. 20676-20679
Mir, M., Asong, J., Li, X., Cardot, J., Boons, G. J., Husson, R. N., (2011) PLOS Pathogens, 7, pp. e1002182
Maestro, B., Novakova, L., Hesek, D., Lee, M., Leyva, E., Mobashery, S., Sanz, J. M., Branny, P., (2011) FEBS Lett, 585, pp. 357-363
Vandal, O. H., Pierini, L. M., Schnappinger, D., Nathan, C. F., Ehrt, S., (2008) Nat Med, 14, pp. 849-854
Patru, M. M., Pavelka, Jr. M. S., (2010) J Bacteriol, 192, pp. 3043-3054
Ruggiero, A., Squeglia, F., Marasco, D., Marchetti, R., Molinaro, A., Berisio, R., (2011) Biochem J, 435, pp. 33-41
Gordon, E., Mouz, N., Duee, E., Dideberg, O., (2000) J Mol Biol, 299, pp. 477-485
Hildebrand, A., Remmert, M., Biegert, A., Soding, (2009) J. Proteins, 77 (SUPPL. 9), pp. 128-132
Mathur, A., Shankaracharya, Vidyarthi, A. S., (2012) J Mol Model, 18, pp. 3021-3023
Cheng, T. J., Sung, M. T., Liao, H. Y., Chang, Y. F., Chen, C. W., Huang, C. Y., Chou, L. Y., Cheng, W. C., (2008) Proc Natl Acad Sci USA, 105, pp. 431-436
Hett, E. C., Chao, M. C., Steyn, A. J., Fortune, S. M., Deng, L. L., Rubin, E., (2007) J. Mol Microbiol, 66, pp. 658-668
Rodriguez, R., Chinea, G., Lopez, N., Pons, T., Vriend, G., (1998) Bioinformatics, 14, pp. 523-528
Koradi, R., Billeter, M., Wuthrich, K., (1996) J Mol Graph, 14, pp. 51-55. , 29-32
Poletto, M., Vascotto, C., Scognamiglio, P. L., Lirussi, L., Marasco, D., Tell, G., (2013) Biochem J, 452, pp. 545-557
Structural and binding properties of the PASTA domain of PonA2, a key penicillin binding protein from Mycobacterium tuberculosis
PonA2 is one of the two class A penicillin binding proteins of Mycobacterium tuberculosis, the etiologic agent of tuberculosis. It plays a complex role in mycobacterial physiology and is spotted as a promising target for inhibitors. PonA2 is involved in adaptation of M. tuberculosis to dormancy, an ability which has been attributed to the presence in its sequence of a C-terminal PASTA domain. Since PASTA modules are typically considered as beta-lactam antibiotic binding domains, we determined the solution structure of the PASTA domain from PonA2 and analyzed its binding properties versus a plethora of potential binders, including the beta-lactam antibiotics, two typical muropeptide mimics, and polymeric peptidoglycan. We show that, despite a high structural similarity with other PASTA domains, the PASTA domain of PonA2 displays different binding properties, as it is not able to bind muropeptides, or beta-lactams, or polymeric peptidoglycan. These results indicate that the role of PASTA domains cannot be generalized, as their specific binding properties strongly depend on surface residues, which are widely variable. (c) 2013 Wiley Periodicals, Inc. Biopolymers 101: 712-719, 2014.
PonA2 is one of the two class A penicillin binding proteins of Mycobacterium tuberculosis, the etiologic agent of tuberculosis. It plays a complex role in mycobacterial physiology and is spotted as a promising target for inhibitors. PonA2 is involved in adaptation of M. tuberculosis to dormancy, an ability which has been attributed to the presence in its sequence of a C-terminal PASTA domain. Since PASTA modules are typically considered as beta-lactam antibiotic binding domains, we determined the solution structure of the PASTA domain from PonA2 and analyzed its binding properties versus a plethora of potential binders, including the beta-lactam antibiotics, two typical muropeptide mimics, and polymeric peptidoglycan. We show that, despite a high structural similarity with other PASTA domains, the PASTA domain of PonA2 displays different binding properties, as it is not able to bind muropeptides, or beta-lactams, or polymeric peptidoglycan. These results indicate that the role of PASTA domains cannot be generalized, as their specific binding properties strongly depend on surface residues, which are widely variable. (c) 2013 Wiley Periodicals, Inc. Biopolymers 101: 712-719, 2014.
Structural and binding properties of the PASTA domain of PonA2, a key penicillin binding protein from Mycobacterium tuberculosis
Structural and binding properties of the PASTA domain of PonA2, a key penicillin binding protein from Mycobacterium tuberculosis
Other filter: ([btitle,keywords] "Tuberculosis" OR [bt ...
De Maio F, Salustri A, Battah B, Palucci I, Marchionni F, Bellesi S, Palmieri V, Papi M, Kramarska E, Sanguinetti M, Sali M, Berisio R, Delogu G
* PE_PGRS3 ensures provision of the vital phospholipids cardiolipin and phosphatidylinositols by promoting the interaction between M. tuberculosis and host cells (19 views)
Virulence (ISSN: 2150-5594linking), 2021 Dec; 12(1): 868-884.
Impact Factor: 5.542
View Export to BibTeX Export to EndNote
Kramarska E, Squeglia F, De Maio F, Delogu G, Berisio R
* PE_PGRS33, an Important Virulence Factor of Mycobacterium tuberculosis and Potential Target of Host Humoral Immune Response (13 views)
Cells (ISSN: 2073-4409linking, 2073-4409electronic), 2021 Jan 15; 10(1): N/D-N/D.
Impact Factor: 6.6
View Export to BibTeX Export to EndNote
Moreira M, Ruggiero A, Esposito L, Choi HG, Kim HJ, Berisio R
* Structural features of HtpGMtb and HtpG-ESAT6Mtb vaccine antigens against tuberculosis: Molecular determinants of antigenic synergy and cytotoxicity modulation (76 views) (PDF 6 views)
Int J Biol Macromol (ISSN: 0141-8130linking, 1879-0003electronic), 2020 May 4; 158: 305-317.
Impact Factor: 6.95
View Export to BibTeX Export to EndNote
De Maio F, Berisio R, Manganelli R, Delogu G
* PE_PGRS proteins of Mycobacterium tuberculosis: A specialized molecular task force at the forefront of host-pathogen interaction (88 views)
Virulence, 2020; N/D: 898-915.
Impact Factor: 5.54
View Export to BibTeX Export to EndNote
Calvanese L, Squeglia F, Romano M, D'Auria G, Falcigno L, Berisio R
* Structural and dynamic studies provide insights into specificity and allosteric regulation of Ribonuclease AS, a key enzyme in mycobacterial virulence (194 views) (PDF 5 views)
J Biomol Struct Dyn (ISSN: 0739-1102linking, 1538-0254electronic), 2020; N/D: 1-19.
Impact Factor: 3.11
View Export to BibTeX Export to EndNote
Mercurio V, Cuomo A, Della Pepa R, Ciervo D, Cella L, Pirozzi F, Parrella P, Campi G, Franco R, Varricchi G, Abete P, Marone G, Petretta M, Bonaduce D, Pacelli R, Picardi M, Tocchetti CG
* What Is the Cardiac Impact of Chemotherapy and Subsequent Radiotherapy in Lymphoma Patients? (172 views)
Antioxid Redox Signal (ISSN: 1523-0864linking, 1557-7716), 2019 Nov 20; 31 (15 ): 1166-1174.
Impact Factor: 7.581
View Export to BibTeX Export to EndNote
Gallo G, Antonucci I, Pirone L, Amoresano A, Contursi P, Limauro D, Pedone E, Bartolucci S, Fiorentino G
* A physicochemical investigation on the metal binding properties of TtSmtB, a thermophilic member of the ArsR/SmtB transcription factor family (187 views)
Int J Biol Macromol (ISSN: 0141-8130linking, 1879-0003electronic), 2019 Jul 26; 138: 1056-1063.
Impact Factor: 4.784
View Export to BibTeX Export to EndNote
Squeglia F, Moreira M, Ruggiero A, Berisio R
* The Cell Wall Hydrolytic NlpC/P60 Endopeptidases in Mycobacterial Cytokinesis: A Structural Perspective (200 views)
Cells (ISSN: 2073-4409linking, 2073-4409electronic), 2019 Jun 18; 8(6): N/D-N/D.
Impact Factor: 5.7
View Export to BibTeX Export to EndNote
Fagoonee S, Pellicano R
* Helicobacter pylori: molecular basis for colonization and survival in gastric environment and resistance to antibiotics. A short review (170 views)
Infect Dis (ISSN: 2374-4243linking), 2019 Jun; 51(6): 399-408.
Impact Factor: 1.47
View Export to BibTeX Export to EndNote
De Maio F, Squeglia F, Goletti D, Delogu G
* The Mycobacterial HBHA Protein: a Promising Biomarker for Tuberculosis (194 views)
Curr Med Chem (ISSN: 0929-8673linking, 1875-533xelectronic), 2018 Oct 29; 26(11): 2051-2060.
Impact Factor: 3.519
View Export to BibTeX Export to EndNote
Squeglia F, Ruggiero A, Berisio R
* Collagen degradation in tuberculosis pathogenesis: the biochemical consequences of hosting an undesired guest (372 views)
Biochem J (ISSN: 1470-8728electronic, 0264-6021linking, 0264-6021print), 2018 Oct 11; 475(19): 3123-3140.
Impact Factor: 4.897
View Export to BibTeX Export to EndNote
Chino M, Zhang SQ, Pirro F, Leone L, Maglio O, Lombardi A, Degrado WF
* Spectroscopic and metal binding properties of a de novo metalloprotein binding a tetrazinc cluster (300 views)
Biopolymers (ISSN: 1097-0282electronic, 0006-3525linking, 0006-3525print), 2018 Sep 11; 109(10): e23339-e23339.
Impact Factor: 2.572
View Export to BibTeX Export to EndNote
Squeglia F, Ruggiero A, Berisio R
* Chemistry of Peptidoglycan in Mycobacterium tuberculosis Life Cycle: An off-the-wall Balance of Synthesis and Degradation (86 views)
Chemistry (ISSN: 0947-6539linking, 1521-3765electronic), 2018 Feb 21; 24 (11 ): 2533-2546.
Impact Factor: 5.476
View Export to BibTeX Export to EndNote
Squeglia F, Ruggiero A, De Simone A, Berisio R
* A structural overview of mycobacterial adhesins: Key biomarkers for diagnostics and therapeutics (240 views)
Protein Sci (ISSN: 1469-896xelectronic, 0961-8368linking), 2018 Feb; 27(2): 369-380.
Impact Factor: 2.523
View Export to BibTeX Export to EndNote
Squeglia F, Ruggiero A, Berisio R
* Chemistry of Peptidoglycan in Mycobacterium tuberculosis life style: an off-the-wall balance of synthesis and degradation (465 views) (PDF 217 views)
Chemistry (ISSN: 1521-3765electronic, 0947-6539linking), 2018; 24: 2533-2546.
Impact Factor: 5.317
View Export to BibTeX Export to EndNote
Pirtskhalava M, Egoyan A, Mirtskhulava M, Roviello GN
* A COMPUTER MODELING STUDY OF BINDING PROPERTIES OF CHIRAL NUCLEOPEPTIDE FOR BIOMEDICAL APPLICATIONS (334 views)
Georgian Med News (ISSN: 1512-0112print, 1512-0112linking), 2017 Dec; (273): 1123-1128.
Impact Factor: 0
View Export to BibTeX Export to EndNote
Berisio R, Squeglia F, Ruggiero A
* Editorial: Molecular Scenarios Behind Infectious Diseases (300 views)
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2017 Nov 24; 24(36): 3939-3941.
Impact Factor: 3.469
View Export to BibTeX Export to EndNote
Squeglia F, Romano M, Ruggiero A, Berisio R
* Molecular players in Tuberculosis drug development: another break in the cell wall (303 views)
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2017 Nov 24; 24(36): 3954-3969.
Impact Factor: 3.469
View Export to BibTeX Export to EndNote
Calvanese L, Falcigno L, Squeglia F, D'Auria G, Berisio R
* PASTA in Penicillin Binding Proteins and Serine/Threonine Kinases: A Recipe of Structural, Dynamic and Binding Properties (294 views)
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2017 Nov 24; 24(36): 4038-4056.
Impact Factor: 3.469
View Export to BibTeX Export to EndNote
Ruggiero A, Squeglia F, Romano M, Vitagliano L, De Simone A, Berisio R
* Structure and dynamics of the multi-domain resuscitation promoting factor RpfB from Mycobacterium tuberculosis (339 views)
J Biomol Struct Dyn (ISSN: 0739-1102, 1538-0254electronic, 0739-1102linking), 2017 May; 35(6): 1322-1330.
Impact Factor: 3.107
View Export to BibTeX Export to EndNote
Diaferia C, Gianolio E, Sibillano T, Mercurio FA, Leone M, Giannini C, Balasco N, Vitagliano L, Morelli G, Accardo A
* Cross-beta nanostructures based on dinaphthylalanine Gd-conjugates loaded with doxorubicin (395 views)
Sci Rep (ISSN: 2045-2322, 2045-2322electronic, 2045-2322linking), 2017 Mar 22; 7(1): 307-307.
Impact Factor: 4.122
View Export to BibTeX Export to EndNote
Roviello GN, Vicidomini C, Di Gaetano S, Capasso D, Musumeci D, Roviello V
* Solid phase synthesis and RNA-binding activity of an arginine-containing nucleopeptide (375 views)
Rsc Adv (ISSN: 2046-2069), 2016; 6(17): 14140-14148.
Impact Factor: 3.108
View Export to BibTeX Export to EndNote
Ruggiero A, Squeglia F, Romano M, Vitagliano L, De Simone A, Berisio R
* The structure of Resuscitation promoting factor B from M. tuberculosis reveals unexpected ubiquitin-like domains (306 views)
Bba-Gen Subjects (ISSN: 0005-2728, 0006-3002print, 1570-9639print), 2015 Nov 5; 1860(2): 445-451.
Impact Factor: 4.864
View Export to BibTeX Export to EndNote
Romano M, Squeglia F, Berisio R
* Structure and Function of RNase AS, a Novel Virulence Factor from Mycobacterium Tuberculosis (382 views)
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2015 Apr 17; 22(14): 1745-1756.
Impact Factor: 3.455
View Export to BibTeX Export to EndNote
Squeglia F, Ruggiero A, Berisio R
* Exit from mycobacterial dormancy: a structural perspective (351 views)
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2015 Feb 9; 22(14): 1698-1709.
Impact Factor: 3.455
View Export to BibTeX Export to EndNote
Squeglia F, Ruggiero A, Romano M, Vitagliano L, Berisio R
* Mutational and structural study of RipA, a key enzyme in Mycobacterium tuberculosis cell division: Evidence for the l-to-d inversion of configuration of the catalytic cysteine (324 views)
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2014 Sep; 70(9): 2295-2300.
Impact Factor: 14.1
View Export to BibTeX Export to EndNote
Romano M, Van De Weerd R, Brouwer FCC, Roviello GN, Lacroix R, Sparrius M, Van Den Brink-van Stempvoort G, Maaskant JJ, Van Der Sar AM, Appelmelk BJ, Geurtsen JJ, Berisio R
* Structure and function of RNase AS, a polyadenylate-specific exoribonuclease affecting mycobacterial virulence in vivo (350 views)
Structure (ISSN: 0969-2126, 1878-4186, 0969-2126linking), 2014 May 6; 22(5): 719-730.
Impact Factor: 5.618
View Export to BibTeX Export to EndNote
Accardo A, Ringhieri P, Palumbo R, Morelli G
* Influence of PEG length on conformational and binding properties of CCK peptides exposed by supramolecular aggregates (365 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2014 Apr; 101(4): 304-312.
Impact Factor: 2.385
View Export to BibTeX Export to EndNote
Calvanese L, Sandomenico A, Caporale A, Focà A, Focà G, D'Auria G, Falcigno L, Ruvo M
* Conformational And Binding Properties Of Nodal Synthetic Fragments (256 views)
Journal Of Peptide Science, 2014; nd: nd-nd.
Impact Factor: 1.862
View Export to BibTeX Export to EndNote
Correale S, Ruggiero A, Capparelli R, Pedone E, Berisio R
* Structures of free and inhibited forms of the L, D-transpeptidase LdtMt1 from Mycobacterium tuberculosis (368 views)
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2013 Sep; 69(Pt9): 1697-1706.
Impact Factor: 7.232
View Export to BibTeX Export to EndNote
Squeglia F, Romano M, Ruggiero A, Vitagliano L, De Simone A, Berisio R
* Carbohydrate recognition by RpfB from mycobacterium tuberculosis unveiled by crystallographic and molecular dynamics analyses (402 views)
Biophysical Journal (ISSN: 0006-3495, 1542-0086), 2013 Jun 4; 104(11): 2530-2539.
Impact Factor: 3.832
View Export to BibTeX Export to EndNote
Falciani C, Brunetti J, Lelli B, Accardo A, Tesauro D, Morelli G, Bracci L
* Nanoparticles exposing neurotensin tumor-specific drivers (407 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2013 Apr; 19(4): 198-204.
Impact Factor: 1.862
View Export to BibTeX Export to EndNote
Accardo A, Mangiapia G, Paduano L, Morelli G, Tesauro D
* Octreotide labeled aggregates containing platinum complexes as nanovectors for drug delivery (374 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2013 Apr; 19(4): 190-197.
Impact Factor: 1.862
View Export to BibTeX Export to EndNote
Correale S, Ruggiero A, Pedone E, Berisio R
* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of the l, d-transpeptidase LdtMt1 from Mycobacterium tuberculosis (349 views)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2013 Mar 1; 69(3): 253-256.
Impact Factor: 0.568
View Export to BibTeX Export to EndNote
Ruggiero A, Marchant J, Squeglia F, Makarov V, De Simone A, Berisio R
* Molecular determinants of inactivation of the resuscitation promoting factor B from Mycobacterium tuberculosis (370 views)
J Biomol Struct Dyn (ISSN: 0739-1102, 1538-0254electronic, 0739-1102linking), 2013 Feb 1; 31(2): 195-205.
Impact Factor: 2.983
View Export to BibTeX Export to EndNote
Coppola D, Abbruzzetti S, Nicoletti F, Merlino A, Gambacurta A, Giordano D, Howes BD, De Sanctis G, Vitagliano L, Bruno S, di Prisco G, Mazzarella L, Smulevich G, Coletta M, Viappiani C, Vergara A, Verde C
* ATP regulation of the ligand-binding properties in temperate and cold-adapted haemoglobins. X-ray structure and ligand-binding kinetics in the sub-Antarctic fish Eleginops maclovinus (310 views)
Molecular Biosystems (ISSN: 1742-206x), 2012 Oct 30; 8(12): 3295-3304.
Impact Factor: 3.35
View Export to BibTeX Export to EndNote
Roviello GN, Roviello G, Musumeci D, Bucci EM, Pedone C
* Dakin-West reaction on 1-thyminyl acetic acid for the synthesis of 1, 3-bis(1-thyminyl)-2-propanone, a heteroaromatic compound with nucleopeptide-binding properties (398 views)
Amino Acids (ISSN: 1438-2199, 0939-4451, 1438-2199electronic), 2012 Oct; 43(4): 1615-1623.
Impact Factor: 3.914
View Export to BibTeX Export to EndNote
Kaprelyants AS, Mukamolova GV, Ruggiero A, Makarov VA, Demina GR, Shleeva MO, Potapov VD, Shramko PA
* Resuscitation-promoting Factors (Rpf): In Search of Inhibitors (451 views)
Protein Pept Lett (ISSN: 0929-8665, 1875-5305), 2012 Oct; 19(10): 1026-1034.
Impact Factor: 1.994
View Export to BibTeX Export to EndNote
Ziaco B, Diana D, Capasso D, Palumbo R, Celentano V, Di Stasi R, Fattorusso R, D'Andrea LD
* C-terminal truncation of Vascular Endothelial Growth Factor mimetic helical peptide preserves structural and receptor binding properties (339 views)
Biochem Biophys Res Commun (ISSN: 0006-291x), 2012 Jul 27; 424(2): 290-294.
Impact Factor: 2.406
View Export to BibTeX Export to EndNote
Esposito C, Cantisani M, D'Auria G, Falcigno L, Pedone E, Galdiero S, Berisio R
* Mapping key interactions in the dimerization process of HBHA from Mycobacterium tuberculosis, insights into bacterial agglutination (396 views)
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 2012 Mar 23; 586(6): 659-667.
Impact Factor: 3.582
View Export to BibTeX Export to EndNote
Castellano I, Merlino A
* γ-glutamyltranspeptidases: Sequence, structure, biochemical properties, and biotechnological applications (392 views)
Cell Mol Life Sci (ISSN: 1420-682x), 2012; 69(20): 3381-3394.
Impact Factor: 5.615
View Export to BibTeX Export to EndNote
Esposito C, Marasco D, Delogu G, Pedone E, Berisio R
* Heparin-binding hemagglutinin HBHA from Mycobacterium tuberculosis affects actin polymerisation (332 views)
Biochem Biophys Res Commun (ISSN: 0006-291x), 2011 Jul 1; 410(2): 339-344.
Impact Factor: 2.484
View Export to BibTeX Export to EndNote
Ruggiero A, Squeglia F, Pirone L, Correale S, Berisio R
* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a major fragment of the resuscitation-promoting factor RpfB from Mycobacterium tuberculosis (374 views)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2011 Jan 1; 67(1): 164-168.
Impact Factor: 0.506
View Export to BibTeX Export to EndNote
D'Auria G, Esposito C, Falcigno L, Calvanese L, Iaccarino E, Ruggiero A, Pedone C, Pedone E, Berisio R
* Dynamical properties of cold shock protein A from Mycobacterium tuberculosis (296 views)
Biochem Biophys Res Commun (ISSN: 0006-291x, 1090-2104, 1090-2104electronic), 2010 Nov 26; 402(4): 693-698.
Impact Factor: 2.595
View Export to BibTeX Export to EndNote
Ruggiero A, Marasco D, Squeglia F, Soldini S, Pedone E, Pedone C, Berisio R
* Structure and functional regulation of RipA, a mycobacterial enzyme essential for daughter cell separation (383 views)
Structure (ISSN: 0969-2126, 1878-4186, 0969-2126linking), 2010 Sep 8; 18(9): 1184-1190.
Impact Factor: 6.337
View Export to BibTeX Export to EndNote
Leone M, Barile E, Vazquez J, Mei A, Guiney D, Dahl R, Pellecchia M
* NMR-based design and evaluation of novel bidentate inhibitors of the protein tyrosine phosphatase YopH (440 views)
Chem Biol Drug Des (ISSN: 1747-0277, 1747-0285), 2010 Jul; 76(1): 10-16.
Impact Factor: 2.527
View Export to BibTeX Export to EndNote
Berisio R, Ruggiero A, Vitagliano L
* Elongation Factors Efia And Ef-Tu: Their Role In Translation And Beyond (509 views)
Israel Journal Of Chemistry, 2010 Jun; 50(1): 71-79.
Impact Factor: 2.561
View Export to BibTeX Export to EndNote
Torres Martin De Rosales R, Faiella M, Farquhar E, Que L, J , Andreozzi C, Pavone V, Maglio O, Nastri F, Lombardi A
* Spectroscopic and metal-binding properties of DF3: an artificial protein able to accommodate different metal ions (293 views)
J Biol Inorg Chem (ISSN: 1432-1327electronic, 0949-8257linking, 0949-8257print), 2010 Jun; 15(5): 717-728.
Impact Factor: 3.287
View Export to BibTeX Export to EndNote
Esposito C, Carullo C, Pedone E, Graziano G, Del Vecchio P, Berisio R
* Dimerisation and structural integrity of Heparin Binding Hemagglutinin A from Mycobacterium tuberculosis: Implications for bacterial agglutination (485 views)
Febs Lett (ISSN: 0014-5793, 0014-5793print, 0014-5793linking), 2010 Mar 19; 584(6): 1091-1096.
Impact Factor: 3.601
View Export to BibTeX Export to EndNote
Ruggiero A, Squeglia F, Esposito C, Marasco D, Pedone E, Pedone C, Berisio R
* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of the resuscitation promoting factor interacting protein RipA from M. tuberculosis (331 views)
Protein Pept Lett (ISSN: 0929-8665, 1875-5305), 2010 Jan; 17(1): 70-73.
Impact Factor: 1.849
View Export to BibTeX Export to EndNote
Sandomenico A, Monti SM, Marasco D, Dathan N, Palumbo R, Saviano M, Ruvo M
* Ige-Binding Properties And Selectivity Of Peptide Mimics Of The Fcvarepsilonri Binding Site (1614 views)
Mol Immunol (ISSN: 0161-5890), 2009 Oct; 46(16): 3300-3309.
Impact Factor: 3.202
View Export to BibTeX Export to EndNote
Giordano D, Boechi L, Vergara A, Marti MA, Samuni U, Dantsker D, Grassi L, Estrin DA, Friedman JM, Mazzarella L, Di Prisco G, Verde C
* The hemoglobins of the sub-Antarctic fish Cottoperca gobio, a phyletically basal species - oxygen-binding equilibria, kinetics and molecular dynamics (662 views)
Febs Journal (ISSN: 1742-464x), 2009 Apr; 276(8): 2266-2277.
Impact Factor: 3.042
View Export to BibTeX Export to EndNote
Wekselman I, Davidovich C, Agmon I, Zimmerman E, Rozenberg H, Bashan A, Berisio R, Yonath A
* Ribosome's mode of function: Myths, facts and recent results (372 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 122-130.
Impact Factor: 1.807
View Export to BibTeX Export to EndNote
Ruggiero A, Tizzano B, Pedone E, Pedone C, Wilmanns M, Berisio R
* Crystal Structure of the Resuscitation-Promoting Factor (Delta DUF)RpfB from M. tuberculosis (527 views)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2009 Jan 9; 385(1): 153-162.
Impact Factor: 3.871
View Export to BibTeX Export to EndNote
Esposito C, Pethoukov MV, Svergun DI, Ruggiero A, Pedone C, Pedone E, Berisio R
* Evidence for an elongated dimeric structure of heparin-binding hemagglutinin from Mycobacterium tuberculosis (436 views)
J Bacteriol Journal Of Bacteriology (ISSN: 0021-9193, 1098-5530), 2008 Jul; 190(13): 4749-4753.
Impact Factor: 3.636
View Export to BibTeX Export to EndNote
Ruggiero A, Tizzano B, Geerlof A, Pedone E, Pedone C, Wilmanns M, Berisio R
* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a resuscitation-promoting factor from Mycobacterium tuberculosis (363 views)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2007 Oct 1; 63(10): 870-873.
Impact Factor: 0.645
View Export to BibTeX Export to EndNote
Pastore C, Franzese M, Sica F, Temussi P, Pastore A
* Understanding the binding properties of an unusual metal-binding protein - a study of bacterial frataxin (347 views)
Febs Journal (ISSN: 1742-464x), 2007 Sep; 274(16): 4199-4210.
Impact Factor: 3.396
View Export to BibTeX Export to EndNote
Agmon I, Amit M, Auerbach T, Bashan A, Baram D, Bartels H, Berisio R, Greenberg I, Harms J, Hansen HAS, Kessler M, Pyetan E, Schluenzen F, Sittner A, Yonath A, Zarivach R
* Ribosomal crystallography: A flexible nucleotide anchoring tRNA translocation, facilitates peptide-bond formation, chirality discrimination and antibiotics synergism (292 views)
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 2004 Jun 1; 567(1): 20-26.
Impact Factor: 3.843
View Export to BibTeX Export to EndNote
Cimino P, Improta R, Bifulco G, Riccio R, Gomez-paloma L, Barone V
* Nucleophilic Cyclopropane Ring Opening in Duocarmycin SA Derivatives by Methanol under Acid Conditions: A Quantum Mechanical Study in the Gas-Phase and in Solution (399 views)
J Org Chem (ISSN: 0022-3263, 0022-3263linking), 2004; 69(8): 2816-2824.
Impact Factor: 3.462
View Export to BibTeX Export to EndNote
Yonath A, Bashan A, Zarivach R, Franceschi F, Schluenzen F, Harms J, Albrecht R, Berisio R
* Methods Of Growing Crystals Of Free, Antibiotic-Complexed, And Substrate-Complexed Large Ribosomal Subunits, And Methods Of Rational Designing Or Identifying Antibiotics Using Structure Coordinate Data Derived From Such Crystals (260 views)
International Publication Number, 2003; N/D: N/D-N/D.
Impact Factor: 4.622
View Export to BibTeX Export to EndNote
Oliva R, Falcigno L, D'Auria G, Zanotti G, Paolillo L
Conformation and calcium-binding properties of a bicyclic nonapeptide (331 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2000; 56(1): 27-36.
Impact Factor: 2.405
View Export to BibTeX Export to EndNote
Ciarmiello A, Del Vecchio S, Silvestro P, Potena MI, Carriero MV, Thomas R, Botti G, D'Aiuto G, Salvatore M
Tumor clearance of technetium 99m-sestamibi as a predictor of response to neoadjuvant chemotherapy for locally advanced breast cancer (432 views)
Journal Of Clinical Oncology (ISSN: 0732-183x), 1998 May; 16(5): 1677-1683.
Impact Factor: 8.228
View Export to BibTeX Export to EndNote
* PE_PGRS3 ensures provision of the vital phospholipids cardiolipin and phosphatidylinositols by promoting the interaction between M. tuberculosis and host cells (19 views)
Virulence (ISSN: 2150-5594linking), 2021 Dec; 12(1): 868-884.
Impact Factor: 5.542
View Export to BibTeX Export to EndNote
Kramarska E, Squeglia F, De Maio F, Delogu G, Berisio R
* PE_PGRS33, an Important Virulence Factor of Mycobacterium tuberculosis and Potential Target of Host Humoral Immune Response (13 views)
Cells (ISSN: 2073-4409linking, 2073-4409electronic), 2021 Jan 15; 10(1): N/D-N/D.
Impact Factor: 6.6
View Export to BibTeX Export to EndNote
Moreira M, Ruggiero A, Esposito L, Choi HG, Kim HJ, Berisio R
* Structural features of HtpGMtb and HtpG-ESAT6Mtb vaccine antigens against tuberculosis: Molecular determinants of antigenic synergy and cytotoxicity modulation (76 views) (PDF 6 views)
Int J Biol Macromol (ISSN: 0141-8130linking, 1879-0003electronic), 2020 May 4; 158: 305-317.
Impact Factor: 6.95
View Export to BibTeX Export to EndNote
De Maio F, Berisio R, Manganelli R, Delogu G
* PE_PGRS proteins of Mycobacterium tuberculosis: A specialized molecular task force at the forefront of host-pathogen interaction (88 views)
Virulence, 2020; N/D: 898-915.
Impact Factor: 5.54
View Export to BibTeX Export to EndNote
Calvanese L, Squeglia F, Romano M, D'Auria G, Falcigno L, Berisio R
* Structural and dynamic studies provide insights into specificity and allosteric regulation of Ribonuclease AS, a key enzyme in mycobacterial virulence (194 views) (PDF 5 views)
J Biomol Struct Dyn (ISSN: 0739-1102linking, 1538-0254electronic), 2020; N/D: 1-19.
Impact Factor: 3.11
View Export to BibTeX Export to EndNote
Mercurio V, Cuomo A, Della Pepa R, Ciervo D, Cella L, Pirozzi F, Parrella P, Campi G, Franco R, Varricchi G, Abete P, Marone G, Petretta M, Bonaduce D, Pacelli R, Picardi M, Tocchetti CG
* What Is the Cardiac Impact of Chemotherapy and Subsequent Radiotherapy in Lymphoma Patients? (172 views)
Antioxid Redox Signal (ISSN: 1523-0864linking, 1557-7716), 2019 Nov 20; 31 (15 ): 1166-1174.
Impact Factor: 7.581
View Export to BibTeX Export to EndNote
Gallo G, Antonucci I, Pirone L, Amoresano A, Contursi P, Limauro D, Pedone E, Bartolucci S, Fiorentino G
* A physicochemical investigation on the metal binding properties of TtSmtB, a thermophilic member of the ArsR/SmtB transcription factor family (187 views)
Int J Biol Macromol (ISSN: 0141-8130linking, 1879-0003electronic), 2019 Jul 26; 138: 1056-1063.
Impact Factor: 4.784
View Export to BibTeX Export to EndNote
Squeglia F, Moreira M, Ruggiero A, Berisio R
* The Cell Wall Hydrolytic NlpC/P60 Endopeptidases in Mycobacterial Cytokinesis: A Structural Perspective (200 views)
Cells (ISSN: 2073-4409linking, 2073-4409electronic), 2019 Jun 18; 8(6): N/D-N/D.
Impact Factor: 5.7
View Export to BibTeX Export to EndNote
Fagoonee S, Pellicano R
* Helicobacter pylori: molecular basis for colonization and survival in gastric environment and resistance to antibiotics. A short review (170 views)
Infect Dis (ISSN: 2374-4243linking), 2019 Jun; 51(6): 399-408.
Impact Factor: 1.47
View Export to BibTeX Export to EndNote
De Maio F, Squeglia F, Goletti D, Delogu G
* The Mycobacterial HBHA Protein: a Promising Biomarker for Tuberculosis (194 views)
Curr Med Chem (ISSN: 0929-8673linking, 1875-533xelectronic), 2018 Oct 29; 26(11): 2051-2060.
Impact Factor: 3.519
View Export to BibTeX Export to EndNote
Squeglia F, Ruggiero A, Berisio R
* Collagen degradation in tuberculosis pathogenesis: the biochemical consequences of hosting an undesired guest (372 views)
Biochem J (ISSN: 1470-8728electronic, 0264-6021linking, 0264-6021print), 2018 Oct 11; 475(19): 3123-3140.
Impact Factor: 4.897
View Export to BibTeX Export to EndNote
Chino M, Zhang SQ, Pirro F, Leone L, Maglio O, Lombardi A, Degrado WF
* Spectroscopic and metal binding properties of a de novo metalloprotein binding a tetrazinc cluster (300 views)
Biopolymers (ISSN: 1097-0282electronic, 0006-3525linking, 0006-3525print), 2018 Sep 11; 109(10): e23339-e23339.
Impact Factor: 2.572
View Export to BibTeX Export to EndNote
Squeglia F, Ruggiero A, Berisio R
* Chemistry of Peptidoglycan in Mycobacterium tuberculosis Life Cycle: An off-the-wall Balance of Synthesis and Degradation (86 views)
Chemistry (ISSN: 0947-6539linking, 1521-3765electronic), 2018 Feb 21; 24 (11 ): 2533-2546.
Impact Factor: 5.476
View Export to BibTeX Export to EndNote
Squeglia F, Ruggiero A, De Simone A, Berisio R
* A structural overview of mycobacterial adhesins: Key biomarkers for diagnostics and therapeutics (240 views)
Protein Sci (ISSN: 1469-896xelectronic, 0961-8368linking), 2018 Feb; 27(2): 369-380.
Impact Factor: 2.523
View Export to BibTeX Export to EndNote
Squeglia F, Ruggiero A, Berisio R
* Chemistry of Peptidoglycan in Mycobacterium tuberculosis life style: an off-the-wall balance of synthesis and degradation (465 views) (PDF 217 views)
Chemistry (ISSN: 1521-3765electronic, 0947-6539linking), 2018; 24: 2533-2546.
Impact Factor: 5.317
View Export to BibTeX Export to EndNote
Pirtskhalava M, Egoyan A, Mirtskhulava M, Roviello GN
* A COMPUTER MODELING STUDY OF BINDING PROPERTIES OF CHIRAL NUCLEOPEPTIDE FOR BIOMEDICAL APPLICATIONS (334 views)
Georgian Med News (ISSN: 1512-0112print, 1512-0112linking), 2017 Dec; (273): 1123-1128.
Impact Factor: 0
View Export to BibTeX Export to EndNote
Berisio R, Squeglia F, Ruggiero A
* Editorial: Molecular Scenarios Behind Infectious Diseases (300 views)
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2017 Nov 24; 24(36): 3939-3941.
Impact Factor: 3.469
View Export to BibTeX Export to EndNote
Squeglia F, Romano M, Ruggiero A, Berisio R
* Molecular players in Tuberculosis drug development: another break in the cell wall (303 views)
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2017 Nov 24; 24(36): 3954-3969.
Impact Factor: 3.469
View Export to BibTeX Export to EndNote
Calvanese L, Falcigno L, Squeglia F, D'Auria G, Berisio R
* PASTA in Penicillin Binding Proteins and Serine/Threonine Kinases: A Recipe of Structural, Dynamic and Binding Properties (294 views)
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2017 Nov 24; 24(36): 4038-4056.
Impact Factor: 3.469
View Export to BibTeX Export to EndNote
Ruggiero A, Squeglia F, Romano M, Vitagliano L, De Simone A, Berisio R
* Structure and dynamics of the multi-domain resuscitation promoting factor RpfB from Mycobacterium tuberculosis (339 views)
J Biomol Struct Dyn (ISSN: 0739-1102, 1538-0254electronic, 0739-1102linking), 2017 May; 35(6): 1322-1330.
Impact Factor: 3.107
View Export to BibTeX Export to EndNote
Diaferia C, Gianolio E, Sibillano T, Mercurio FA, Leone M, Giannini C, Balasco N, Vitagliano L, Morelli G, Accardo A
* Cross-beta nanostructures based on dinaphthylalanine Gd-conjugates loaded with doxorubicin (395 views)
Sci Rep (ISSN: 2045-2322, 2045-2322electronic, 2045-2322linking), 2017 Mar 22; 7(1): 307-307.
Impact Factor: 4.122
View Export to BibTeX Export to EndNote
Roviello GN, Vicidomini C, Di Gaetano S, Capasso D, Musumeci D, Roviello V
* Solid phase synthesis and RNA-binding activity of an arginine-containing nucleopeptide (375 views)
Rsc Adv (ISSN: 2046-2069), 2016; 6(17): 14140-14148.
Impact Factor: 3.108
View Export to BibTeX Export to EndNote
Ruggiero A, Squeglia F, Romano M, Vitagliano L, De Simone A, Berisio R
* The structure of Resuscitation promoting factor B from M. tuberculosis reveals unexpected ubiquitin-like domains (306 views)
Bba-Gen Subjects (ISSN: 0005-2728, 0006-3002print, 1570-9639print), 2015 Nov 5; 1860(2): 445-451.
Impact Factor: 4.864
View Export to BibTeX Export to EndNote
Romano M, Squeglia F, Berisio R
* Structure and Function of RNase AS, a Novel Virulence Factor from Mycobacterium Tuberculosis (382 views)
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2015 Apr 17; 22(14): 1745-1756.
Impact Factor: 3.455
View Export to BibTeX Export to EndNote
Squeglia F, Ruggiero A, Berisio R
* Exit from mycobacterial dormancy: a structural perspective (351 views)
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2015 Feb 9; 22(14): 1698-1709.
Impact Factor: 3.455
View Export to BibTeX Export to EndNote
Squeglia F, Ruggiero A, Romano M, Vitagliano L, Berisio R
* Mutational and structural study of RipA, a key enzyme in Mycobacterium tuberculosis cell division: Evidence for the l-to-d inversion of configuration of the catalytic cysteine (324 views)
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2014 Sep; 70(9): 2295-2300.
Impact Factor: 14.1
View Export to BibTeX Export to EndNote
Romano M, Van De Weerd R, Brouwer FCC, Roviello GN, Lacroix R, Sparrius M, Van Den Brink-van Stempvoort G, Maaskant JJ, Van Der Sar AM, Appelmelk BJ, Geurtsen JJ, Berisio R
* Structure and function of RNase AS, a polyadenylate-specific exoribonuclease affecting mycobacterial virulence in vivo (350 views)
Structure (ISSN: 0969-2126, 1878-4186, 0969-2126linking), 2014 May 6; 22(5): 719-730.
Impact Factor: 5.618
View Export to BibTeX Export to EndNote
Accardo A, Ringhieri P, Palumbo R, Morelli G
* Influence of PEG length on conformational and binding properties of CCK peptides exposed by supramolecular aggregates (365 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2014 Apr; 101(4): 304-312.
Impact Factor: 2.385
View Export to BibTeX Export to EndNote
Calvanese L, Sandomenico A, Caporale A, Focà A, Focà G, D'Auria G, Falcigno L, Ruvo M
* Conformational And Binding Properties Of Nodal Synthetic Fragments (256 views)
Journal Of Peptide Science, 2014; nd: nd-nd.
Impact Factor: 1.862
View Export to BibTeX Export to EndNote
Correale S, Ruggiero A, Capparelli R, Pedone E, Berisio R
* Structures of free and inhibited forms of the L, D-transpeptidase LdtMt1 from Mycobacterium tuberculosis (368 views)
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2013 Sep; 69(Pt9): 1697-1706.
Impact Factor: 7.232
View Export to BibTeX Export to EndNote
Squeglia F, Romano M, Ruggiero A, Vitagliano L, De Simone A, Berisio R
* Carbohydrate recognition by RpfB from mycobacterium tuberculosis unveiled by crystallographic and molecular dynamics analyses (402 views)
Biophysical Journal (ISSN: 0006-3495, 1542-0086), 2013 Jun 4; 104(11): 2530-2539.
Impact Factor: 3.832
View Export to BibTeX Export to EndNote
Falciani C, Brunetti J, Lelli B, Accardo A, Tesauro D, Morelli G, Bracci L
* Nanoparticles exposing neurotensin tumor-specific drivers (407 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2013 Apr; 19(4): 198-204.
Impact Factor: 1.862
View Export to BibTeX Export to EndNote
Accardo A, Mangiapia G, Paduano L, Morelli G, Tesauro D
* Octreotide labeled aggregates containing platinum complexes as nanovectors for drug delivery (374 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2013 Apr; 19(4): 190-197.
Impact Factor: 1.862
View Export to BibTeX Export to EndNote
Correale S, Ruggiero A, Pedone E, Berisio R
* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of the l, d-transpeptidase LdtMt1 from Mycobacterium tuberculosis (349 views)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2013 Mar 1; 69(3): 253-256.
Impact Factor: 0.568
View Export to BibTeX Export to EndNote
Ruggiero A, Marchant J, Squeglia F, Makarov V, De Simone A, Berisio R
* Molecular determinants of inactivation of the resuscitation promoting factor B from Mycobacterium tuberculosis (370 views)
J Biomol Struct Dyn (ISSN: 0739-1102, 1538-0254electronic, 0739-1102linking), 2013 Feb 1; 31(2): 195-205.
Impact Factor: 2.983
View Export to BibTeX Export to EndNote
Coppola D, Abbruzzetti S, Nicoletti F, Merlino A, Gambacurta A, Giordano D, Howes BD, De Sanctis G, Vitagliano L, Bruno S, di Prisco G, Mazzarella L, Smulevich G, Coletta M, Viappiani C, Vergara A, Verde C
* ATP regulation of the ligand-binding properties in temperate and cold-adapted haemoglobins. X-ray structure and ligand-binding kinetics in the sub-Antarctic fish Eleginops maclovinus (310 views)
Molecular Biosystems (ISSN: 1742-206x), 2012 Oct 30; 8(12): 3295-3304.
Impact Factor: 3.35
View Export to BibTeX Export to EndNote
Roviello GN, Roviello G, Musumeci D, Bucci EM, Pedone C
* Dakin-West reaction on 1-thyminyl acetic acid for the synthesis of 1, 3-bis(1-thyminyl)-2-propanone, a heteroaromatic compound with nucleopeptide-binding properties (398 views)
Amino Acids (ISSN: 1438-2199, 0939-4451, 1438-2199electronic), 2012 Oct; 43(4): 1615-1623.
Impact Factor: 3.914
View Export to BibTeX Export to EndNote
Kaprelyants AS, Mukamolova GV, Ruggiero A, Makarov VA, Demina GR, Shleeva MO, Potapov VD, Shramko PA
* Resuscitation-promoting Factors (Rpf): In Search of Inhibitors (451 views)
Protein Pept Lett (ISSN: 0929-8665, 1875-5305), 2012 Oct; 19(10): 1026-1034.
Impact Factor: 1.994
View Export to BibTeX Export to EndNote
Ziaco B, Diana D, Capasso D, Palumbo R, Celentano V, Di Stasi R, Fattorusso R, D'Andrea LD
* C-terminal truncation of Vascular Endothelial Growth Factor mimetic helical peptide preserves structural and receptor binding properties (339 views)
Biochem Biophys Res Commun (ISSN: 0006-291x), 2012 Jul 27; 424(2): 290-294.
Impact Factor: 2.406
View Export to BibTeX Export to EndNote
Esposito C, Cantisani M, D'Auria G, Falcigno L, Pedone E, Galdiero S, Berisio R
* Mapping key interactions in the dimerization process of HBHA from Mycobacterium tuberculosis, insights into bacterial agglutination (396 views)
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 2012 Mar 23; 586(6): 659-667.
Impact Factor: 3.582
View Export to BibTeX Export to EndNote
Castellano I, Merlino A
* γ-glutamyltranspeptidases: Sequence, structure, biochemical properties, and biotechnological applications (392 views)
Cell Mol Life Sci (ISSN: 1420-682x), 2012; 69(20): 3381-3394.
Impact Factor: 5.615
View Export to BibTeX Export to EndNote
Esposito C, Marasco D, Delogu G, Pedone E, Berisio R
* Heparin-binding hemagglutinin HBHA from Mycobacterium tuberculosis affects actin polymerisation (332 views)
Biochem Biophys Res Commun (ISSN: 0006-291x), 2011 Jul 1; 410(2): 339-344.
Impact Factor: 2.484
View Export to BibTeX Export to EndNote
Ruggiero A, Squeglia F, Pirone L, Correale S, Berisio R
* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a major fragment of the resuscitation-promoting factor RpfB from Mycobacterium tuberculosis (374 views)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2011 Jan 1; 67(1): 164-168.
Impact Factor: 0.506
View Export to BibTeX Export to EndNote
D'Auria G, Esposito C, Falcigno L, Calvanese L, Iaccarino E, Ruggiero A, Pedone C, Pedone E, Berisio R
* Dynamical properties of cold shock protein A from Mycobacterium tuberculosis (296 views)
Biochem Biophys Res Commun (ISSN: 0006-291x, 1090-2104, 1090-2104electronic), 2010 Nov 26; 402(4): 693-698.
Impact Factor: 2.595
View Export to BibTeX Export to EndNote
Ruggiero A, Marasco D, Squeglia F, Soldini S, Pedone E, Pedone C, Berisio R
* Structure and functional regulation of RipA, a mycobacterial enzyme essential for daughter cell separation (383 views)
Structure (ISSN: 0969-2126, 1878-4186, 0969-2126linking), 2010 Sep 8; 18(9): 1184-1190.
Impact Factor: 6.337
View Export to BibTeX Export to EndNote
Leone M, Barile E, Vazquez J, Mei A, Guiney D, Dahl R, Pellecchia M
* NMR-based design and evaluation of novel bidentate inhibitors of the protein tyrosine phosphatase YopH (440 views)
Chem Biol Drug Des (ISSN: 1747-0277, 1747-0285), 2010 Jul; 76(1): 10-16.
Impact Factor: 2.527
View Export to BibTeX Export to EndNote
Berisio R, Ruggiero A, Vitagliano L
* Elongation Factors Efia And Ef-Tu: Their Role In Translation And Beyond (509 views)
Israel Journal Of Chemistry, 2010 Jun; 50(1): 71-79.
Impact Factor: 2.561
View Export to BibTeX Export to EndNote
Torres Martin De Rosales R, Faiella M, Farquhar E, Que L, J , Andreozzi C, Pavone V, Maglio O, Nastri F, Lombardi A
* Spectroscopic and metal-binding properties of DF3: an artificial protein able to accommodate different metal ions (293 views)
J Biol Inorg Chem (ISSN: 1432-1327electronic, 0949-8257linking, 0949-8257print), 2010 Jun; 15(5): 717-728.
Impact Factor: 3.287
View Export to BibTeX Export to EndNote
Esposito C, Carullo C, Pedone E, Graziano G, Del Vecchio P, Berisio R
* Dimerisation and structural integrity of Heparin Binding Hemagglutinin A from Mycobacterium tuberculosis: Implications for bacterial agglutination (485 views)
Febs Lett (ISSN: 0014-5793, 0014-5793print, 0014-5793linking), 2010 Mar 19; 584(6): 1091-1096.
Impact Factor: 3.601
View Export to BibTeX Export to EndNote
Ruggiero A, Squeglia F, Esposito C, Marasco D, Pedone E, Pedone C, Berisio R
* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of the resuscitation promoting factor interacting protein RipA from M. tuberculosis (331 views)
Protein Pept Lett (ISSN: 0929-8665, 1875-5305), 2010 Jan; 17(1): 70-73.
Impact Factor: 1.849
View Export to BibTeX Export to EndNote
Sandomenico A, Monti SM, Marasco D, Dathan N, Palumbo R, Saviano M, Ruvo M
* Ige-Binding Properties And Selectivity Of Peptide Mimics Of The Fcvarepsilonri Binding Site (1614 views)
Mol Immunol (ISSN: 0161-5890), 2009 Oct; 46(16): 3300-3309.
Impact Factor: 3.202
View Export to BibTeX Export to EndNote
Giordano D, Boechi L, Vergara A, Marti MA, Samuni U, Dantsker D, Grassi L, Estrin DA, Friedman JM, Mazzarella L, Di Prisco G, Verde C
* The hemoglobins of the sub-Antarctic fish Cottoperca gobio, a phyletically basal species - oxygen-binding equilibria, kinetics and molecular dynamics (662 views)
Febs Journal (ISSN: 1742-464x), 2009 Apr; 276(8): 2266-2277.
Impact Factor: 3.042
View Export to BibTeX Export to EndNote
Wekselman I, Davidovich C, Agmon I, Zimmerman E, Rozenberg H, Bashan A, Berisio R, Yonath A
* Ribosome's mode of function: Myths, facts and recent results (372 views)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 122-130.
Impact Factor: 1.807
View Export to BibTeX Export to EndNote
Ruggiero A, Tizzano B, Pedone E, Pedone C, Wilmanns M, Berisio R
* Crystal Structure of the Resuscitation-Promoting Factor (Delta DUF)RpfB from M. tuberculosis (527 views)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2009 Jan 9; 385(1): 153-162.
Impact Factor: 3.871
View Export to BibTeX Export to EndNote
Esposito C, Pethoukov MV, Svergun DI, Ruggiero A, Pedone C, Pedone E, Berisio R
* Evidence for an elongated dimeric structure of heparin-binding hemagglutinin from Mycobacterium tuberculosis (436 views)
J Bacteriol Journal Of Bacteriology (ISSN: 0021-9193, 1098-5530), 2008 Jul; 190(13): 4749-4753.
Impact Factor: 3.636
View Export to BibTeX Export to EndNote
Ruggiero A, Tizzano B, Geerlof A, Pedone E, Pedone C, Wilmanns M, Berisio R
* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a resuscitation-promoting factor from Mycobacterium tuberculosis (363 views)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2007 Oct 1; 63(10): 870-873.
Impact Factor: 0.645
View Export to BibTeX Export to EndNote
Pastore C, Franzese M, Sica F, Temussi P, Pastore A
* Understanding the binding properties of an unusual metal-binding protein - a study of bacterial frataxin (347 views)
Febs Journal (ISSN: 1742-464x), 2007 Sep; 274(16): 4199-4210.
Impact Factor: 3.396
View Export to BibTeX Export to EndNote
Agmon I, Amit M, Auerbach T, Bashan A, Baram D, Bartels H, Berisio R, Greenberg I, Harms J, Hansen HAS, Kessler M, Pyetan E, Schluenzen F, Sittner A, Yonath A, Zarivach R
* Ribosomal crystallography: A flexible nucleotide anchoring tRNA translocation, facilitates peptide-bond formation, chirality discrimination and antibiotics synergism (292 views)
Febs Lett (ISSN: 0014-5793, 0014-5793print, 1873-3468electronic), 2004 Jun 1; 567(1): 20-26.
Impact Factor: 3.843
View Export to BibTeX Export to EndNote
Cimino P, Improta R, Bifulco G, Riccio R, Gomez-paloma L, Barone V
* Nucleophilic Cyclopropane Ring Opening in Duocarmycin SA Derivatives by Methanol under Acid Conditions: A Quantum Mechanical Study in the Gas-Phase and in Solution (399 views)
J Org Chem (ISSN: 0022-3263, 0022-3263linking), 2004; 69(8): 2816-2824.
Impact Factor: 3.462
View Export to BibTeX Export to EndNote
Yonath A, Bashan A, Zarivach R, Franceschi F, Schluenzen F, Harms J, Albrecht R, Berisio R
* Methods Of Growing Crystals Of Free, Antibiotic-Complexed, And Substrate-Complexed Large Ribosomal Subunits, And Methods Of Rational Designing Or Identifying Antibiotics Using Structure Coordinate Data Derived From Such Crystals (260 views)
International Publication Number, 2003; N/D: N/D-N/D.
Impact Factor: 4.622
View Export to BibTeX Export to EndNote
Oliva R, Falcigno L, D'Auria G, Zanotti G, Paolillo L
Conformation and calcium-binding properties of a bicyclic nonapeptide (331 views)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2000; 56(1): 27-36.
Impact Factor: 2.405
View Export to BibTeX Export to EndNote
Ciarmiello A, Del Vecchio S, Silvestro P, Potena MI, Carriero MV, Thomas R, Botti G, D'Aiuto G, Salvatore M
Tumor clearance of technetium 99m-sestamibi as a predictor of response to neoadjuvant chemotherapy for locally advanced breast cancer (432 views)
Journal Of Clinical Oncology (ISSN: 0732-183x), 1998 May; 16(5): 1677-1683.
Impact Factor: 8.228
View Export to BibTeX Export to EndNote
62 Records (61 excluding Abstracts).
Total impact factor: 235.17 (233.308 excluding Abstracts).
Total 5 year impact factor: 227.912 (226.197 excluding Abstracts).
Total impact factor: 235.17 (233.308 excluding Abstracts).
Total 5 year impact factor: 227.912 (226.197 excluding Abstracts).
449 views. Last view on Thursday 08 September 2022, 1:28:47
ibb.cnr.it