Semiautomatic regional segmentation to measure orbital fat volumes in thyroid-associated ophthalmopathy. A validation study
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Semiautomatic regional segmentation to measure orbital fat volumes in thyroid-associated ophthalmopathy. A validation study (219 visite) (PDF privato 163 visite)

Comerci M, Elefante A, Strianese D, Senese R, Bonavolonta P, Alfano B, Bonavolonta B, Brunetti A

Neuroradiol J (ISSN: 1971-4009, 1971-4009print, 1971-4009linking), 2013 Aug; 26(4): 373-379.



Tipo di articolo: Journal Article, Clinical Trial, Validation Studies,

Impact factor: 2.16, Impact factor a 5 anni: 2.304

Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84884711917&partnerID=40&md5=61e04db53b2edda52d151d2887c8bf4f

Parole chiave: Graves, Orbitopathy, Mri Segmentation, Orbital Quadrant Definition, Regional Orbital Fat Quantification, Semiautomatic Numeric Segmentation, Validation, Adipose Tissue, Adult, Article, Clinical Article, Controlled Study, Endocrine Ophthalmopathy, Female, Graves Disease, Human, Measurement, Nuclear Magnetic Resonance Imaging, Validation Study, Exophthalmos, Graves Ophthalmopathy, Middle Aged, Reproducibility Of Results, Adipose Tissue Pathology, Exophthalmos Pathology, Graves Ophthalmopathy Pathology, Magnetic Resonance Imaging Methods Standards, Orbit Pathology,

Affiliazioni:

*** IBB - CNR ***
Biostructure and Bioimaging Institute, National Research Council, Naples, Italy
Department of Advanced Biomedical Sciences, Neuroradiology, Federico II University, Naples, Italy
Department of Neurosciences, Reproductive Sciences and Odontostomatology, Federico II University, Naples, Italy
Naples, Italy - marco. comerci@ibb. cnr. it.
Consiglio Nazionale delle Ricerche
Universita degli Studi di Napoli Federico II


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Peyster, R.G., Ginsberg, F., Silber, J.H., Adler, L.P., Exophthalmos caused by excessive fat: CT volumetric analysis and differential diagnosis (1986) American Journal of Roentgenology, 146 (3), pp. 459-464

Weetman, A.P., Cohen, S., Gatter, K.C., Fells, P., Shine, B., Immunohistochemical analysis of the retrobulbar tissues in Graves' ophthalmopathy (1989) Clinical and Experimental Immunology, 75 (2), pp. 222-227

Bartley, G.B., Fatourechi, V., Kadrmas, E.F., Jacobsen, S.J., Ilstrup, D.M., Garrity, J.A., Gorman, C.A., Clinical features of Graves' ophthalmopathy in an incidence cohort (1996) American Journal of Ophthalmology, 121 (3), pp. 284-290

Feldon, S.E., Lee, C.P., Muramatsu, S.K., Weiner, J.M., Quantitative computed tomography of Graves' ophthalmopathy. Extraocular muscle and orbital fat in development of optic neuropathy (1985) Archives of Ophthalmology, 103 (2), pp. 213-215

Boboridis, K.G., Gogakos, A., Krassas, G.E., Orbital fat decompression for Graves' orbitopathy: A literature review (2010) Pediatr Endocrinol Rev, 7 (SUPPL. 2), pp. 222-226

Prummel, M.F., Gerding, M.N., Zonneveld, F.W., Wiersinga, W.M., The usefulness of quantitative orbital magnetic resonance imaging in Graves' ophthalmopathy (2001) Clinical Endocrinology, 54 (2), pp. 205-209. , DOI 10.1046/j.1365-2265.2001.01220.x

Dolman, P.J., Cahill, K., Czyz, C.N., Reliability of estimating ductions in thyroid eye disease: An International Thyroid Eye Disease Society multicenter study (2012) Ophthalmology, 119 (2), pp. 382-389

Ossoinig, K.C., The role of standardized ophthalmic echography in the management of Graves' ophthalmopathy (1989) Dev Ophthalmol, 20, pp. 28-37

Feldon, S.E., Weiner, J.M., Clinical significance of extraocular muscle volumes in Graves' ophthalmopathy. A quantitative computed tomography study (1982) Archives of Ophthalmology, 100 (8), pp. 1266-1269

Bahn, R.S., Clinical review 157 - Pathophysiology of Graves' ophthalmopathy: The cycle of disease (2003) Journal of Clinical Endocrinology and Metabolism, 88 (5), pp. 1939-1946. , DOI 10.1210/jc.2002-030010

Ben, S.G.J., Schwarcz, R.M., Mansury, A.M., Wang, L., McCann, J.D., Goldberg, R.A., Minimally invasive orbital decompression: Local anesthesia and hand-carved bone (2005) Archives of Ophthalmology, 123 (12), pp. 1671-1675. , http://archopht.ama-assn.org/cgi/reprint/123/12/1671, DOI 10.1001/archopht.123.12.1671



This study was designed to validate a novel semi-automated segmentation method to measure regional intra-orbital fat tissue volume in Graves' ophthalmopathy. Twenty-four orbits from 12 patients with Graves' ophthalmopathy, 24 orbits from 12 controls, ten orbits from five MRI study simulations and two orbits from a digital model were used. Following manual region of interest definition of the orbital volumes performed by two operators with different levels of expertise, an automated procedure calculated intra-orbital fat tissue volumes (global and regional, with automated definition of four quadrants). In patients with Graves' disease, clinical activity score and degree of exophthalmos were measured and correlated with intra-orbital fat volumes. Operator performance was evaluated and statistical analysis of the measurements was performed. Accurate intra-orbital fat volume measurements were obtained with coefficients of variation below 5\\%. The mean operator difference in total fat volume measurements was 0.56\\%. Patients had significantly higher intra-orbital fat volumes than controls (p<0.001 using Student's t test). Fat volumes and clinical score were significantly correlated (p<0.001). The semi-automated method described here can provide accurate, reproducible intra-orbital fat measurements with low inter-operator variation and good correlation with clinical data.
Nessun risultato.

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Cittadini A, Fazio S, Stromer H, Cuocolo A, Sabatini D, Imbriaco M, Sacca L, Douglas PS
New method for optimal echo determination of right ventricular filling: Scintigraphic validation and application in hypertension (77 visite)
Circulationcirculation (ISSN: 0009-7322), 1994; 90(4PART2): N/D-N/D.
Impact Factor: 9.762
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Testino G, Leone S, Fagoonee S, Del Bas JM, Rodriguez B, Puiggros F, Marine S, Rodriguez MA, Morina D, Armengol L, Caimari A, Arola L, Cimini FA, Barchetta I, Carotti S, Bertoccini L, Baroni MG, Vespasiani-gentilucci U, Cavallo MG, Morini S, Nelson JE, Roth CL, Wilson LA, Yates KP, Aouizerat B, Morgan-stevenson V, Whalen E, Hoofnagle A, Mason M, Gersuk V, Yeh MM, Kowdley KV, Lee SM, Jun DW, Cho YK, Jang KS, Kucukazman M, Ata N, Dal K, Yeniova AO, Kefeli A, Basyigit S, Aktas B, Akin KO, Agladioglu K, Ure OS, Topal F, Nazligul Y, Beyan E, Ertugrul DT, Catena C, Cosma C, Camozzi V, Plebani M, Ermani M, Sechi LA, Fallo F, Goto Y, Ray MB, Mendenhall CL, French SW, Gartside PS
Serum vitamin A deficiency and increased intrahepatic expression of cytokeratin antigen in alcoholic liver disease (9 visite)
Hepatology (ISSN: 1827-1669electronic, 0026-4806linking), 1988 Sep; 83120693611123109(5): 1019-1026.
Impact Factor: 0.913
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35 Records (30 escludendo Abstract e Conferenze).
Impact factor totale: 132.757 (111.027 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 144.121 (119.035 escludendo Abstract e Conferenze).







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