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Beta-Hairpin Peptide That Targets Vascular Endothelial Growth Factor (vegf) Receptors: Design, Nmr Characterization, And Biological Activity (156 visite)

Diana D, Basile A, De Rosa L, Di Stasi R, Auriemma S, Arra C, Pedone C, Turco MC, Fattorusso R, D'Andrea LD

J Biol Chem Journal Of Biological Chemistry (ISSN: 1083-351x, 0021-9258), 2011 Dec 2; 286(48): 41680-41691.

Tipo di articolo: Journal Article, , Impact factor: 4.773, Impact factor a 5 anni: 5.117, Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-82355184426&partnerID=40&md5=6d8ea0e1943d3238fdaa4bf2584a162b

Parole chiave: Angiogenesis, Cell Binding, Conformational Analysis, Growth Factor, In-Vitro, Interaction Analysis, Intracellular Pathways, Molecular Levels, Proangiogenic Activities, Pure Water, Receptor Binding, Therapeutic Angiogenesis, Vascular Endothelial Growth Factor, X-Ray Structure, Bioactivity, Cell Death, Cell Proliferation, Endothelial Cells, Medical Applications, Peptides, Glutamine, Peptide Derivative, Placental Growth Factor, Valine, Vasculotropin Receptor, Animal Cell, Apoptosis, Article, Controlled Study, Endothelium Cell, Female, Human, Human Cell, In Vitro Study, In Vivo Study, Molecular Recognition, Mouse, Nonhuman, Nuclear Magnetic Resonance Spectroscopy, Priority Journal, Protein Binding, Protein Conformation, Protein Folding, Protein Function, Protein Interaction, Protein Structure, Protein Targeting, Biomolecular, Secondary, Vascular Endothelial Growth Factor Receptor-1,

Affiliazioni: *** IBB - CNR ***
Istituto di Biostrutture e Bioimmagini, Consiglio Nazionale Delle Ricerche, via Mezzocannone 16, 80134 Napoli, Italy
Dipartimento di Scienze Farmaceutiche e Biomediche, Universit di Salerno, via Ponte don Melillo, 84084 Fisciano (Salerno), Italy
Dipartimento Delle Scienze Biologiche, Universit di Napoli Federico II, via Mezzocannone 16, 80134 Napoli, Italy
Istituto Nazionale Tumori Fondazione G. Pascale, via Mariano Semmola 49, 80131 Napoli, Italy


Riferimenti: Ferrara, N., Davis-Smyth, T., (1997) Endocr. Rev., 18, pp. 4-2

Nagy, J. A., Dvorak, A. M., Dvorak, H. F., (2007) Annu. Rev. Pathol., 2, pp. 251-275

Ferrara, N., Gerber, H. P., LeCounter, J., (2003) Nat. Med., 9, pp. 669-676

Olsson, A. K., Dimberg, A., Kreuger, J., Claesson-Welsh, L., (2006) Nat. Rev. Mol. Cell Biol., 7, pp. 359-371

De Falco, S., Gigante, B., Persico, M. G., (2002) Trends Cardiovasc. Med., 12, pp. 241-246

Fischer, C., Mazzone, M., Jonckx, B., Carmeliet, P., (2008) Nat. Rev. Cancer, 8, pp. 942-956

Cao, Y., (2009) Sci. Signal., 2, pp. re1

Wiesmann, C., Fuh, G., Christinger, H. W., Eigenbrot, C., Wells, J. A., De Vos, A. M., (1997) Cell, 91, pp. 695-704

Di Stasi, R., Diana, D., Capasso, D., Palumbo, R., Romanelli, A., Pedone, C., Fattorusso, R., D'Andrea, L. D., (2010) Biopolymers, 94, pp. 800-809

Goddard, T. D., Kneller, D. G., (2001) SPARKY, , Version 3, University of California, San Francisco, CA

Masse, J. E., Keller, R., (2005) J. Magn. Reson., 174, pp. 133-151

Herrmann, T., G ntert, P., W thrich, K., (2002) J. Mol. Biol., 319, pp. 209-227

Koradi, R., Billeter, M., W thrich, K., (1996) J. Mol. Graph., 14, pp. 51-55+29-32

Guex, N., Peitsch, M. C., (1997) Electrophoresis, 18, pp. 2714-2723

Morris, K. F., Johnson, G. S., (1992) J. Am. Chem. Soc., 114, pp. 3139-3141

Maynard, A. J., Sharman, G. J., Searle, M. S., (1998) J. Am. Chem. Soc., 120, pp. 1996-2007

Fielding, L., (2003) Curr. Top. Med. Chem., 3, pp. 39-53

Cochran, A. G., Skelton, N. J., Starovasnik, M. A., (2001) Proc. Natl. Acad. Sci. U. S. A., 98, pp. 5578-5583

Yao, S., Howlett, G. J., Norton, R. S., (2000) J. Biomol. NMR, 16, pp. 109-119

W thrich, K., (1986) NMRof Proteins and Nucleic Acids, , Wiley, New York

Wishart, D. S., Sykes, B. D., Richards, F. M., (1991) J. Mol. Biol., 222, pp. 311-333

Eidenschink, L., Kier, B. L., Huggins, K. N., Andersen, N. H., (2009) Proteins, 75, pp. 308-322

Blanco, F. J., Jim nez, M. A., Pineda, A., Rico, M., Santoro, J., Nieto, J. L., (1994) Biochemistry, 33, pp. 6004-6014

Gautier, B., Goncalves, V., Diana, D., Di Stasi, R., Teillet, F., Lenoir, C., Huguenot, F., Inguimbert, N., (2010) J. Med. Chem., 53, pp. 4428-4440

Farmer II, B. T., Constantine, K. L., Goldfarb, V., Friedrichs, M. S., Wittekind, M., Yanchunas Jr., J., Robertson, J. G., Mueller, L., (1996) Nat. Struct. Biol., 3, pp. 995-997

Yilmaz, A., Kliche, S., Mayr-Beyrle, U., Fellbrich, G., Waltenberger, J., (2003) Biochem. Biophys. Res. Commun., 306, pp. 730-736

Diana, D., Ziaco, B., Colombo, G., Scarabelli, G., Romanelli, A., Pedone, C., Fattorusso, R., D'Andrea, L. D., (2008) Chemistry, 14, pp. 4164-4166

Dudar, G. K., D'Andrea, L. D., Di Stasi, R., Pedone, C., Wallace, J. L., (2008) Am. J. Physiol. Gastrointest. Liver Physiol., 295, pp. G374-G381

Santulli, G., Ciccarelli, M., Palumbo, G., Campanile, A., Galasso, G., Ziaco, B., Altobelli, G. G., Iaccarino, G., (2009) J. Transl. Med., 7, pp. 41-50

Keyt, B. A., Nguyen, H. V., Berleau, L. T., Duarte, C. M., Park, J., Chen, H., Ferrara, N., (1996) J. Biol. Chem., 271, pp. 5638-5646

Lepp nen, V. M., Prota, A. E., Jeltsch, M., Anisimov, A., Kalkkinen, N., Strandin, T., Lankinen, H., Alitalo, K., (2010) Proc. Natl. Acad. Sci. U. S. A., 107, pp. 2425-2430

Zilberberg, L., Shinkaruk, S., Lequin, O., Rousseau, B., Hagedorn, M., Costa, F., Caronzolo, D., Bikfalvi, A., (2003) J. Biol. Chem., 278, pp. 35564-35573

Garc a-Aranda, M. I., Marrero, P., Gautier, B., Mart n- Mart nez, M., Inguimbert, N., Vidal, M., Garc a-L pez, M. T., P rez De Vega, M. J., (2011) Bioorg. Med. Chem., 19, pp. 1978-1986

Vicari, D., Foy, K. C., Liotta, E. M., Kaumaya, P. T., (2011) J. Biol. Chem., 286, pp. 13612-13625. , 2011

Mirassou, Y., Santiveri, C. M., P rez De Vega, M. J., Gonz lez- Mu iz, R., Jim nez, M. A., (2009) ChemBioChem, 10, pp. 902-910

Santiveri, C. M., Jim nez, M. A., (2010) Biopolymers, 94, pp. 779-790

Russell, S. J., Blandl, T., Skelton, N. J., Cochran, A. G., (2003) J. Am. Chem. Soc., 125, pp. 388-395

Pastor, M. T., Gim nez-Giner, A., P rez-Pay, E., (2005) ChemBioChem, 6, pp. 1753-1756

Blanco, F., Ram rez-Alvarado, M., Serrano, L., (1998) Curr. Opin. Struct. Biol., 8, pp. 107-111

Pedram, A., Razandi, M., Levin, E. R., (1998) J. Biol. Chem., 273, pp. 26722-26728

Fujio, Y., Walsh, K., (1999) J. Biol. Chem., 274, pp. 16349-16354

Bais, C., Wu, X., Yao, J., Yang, S., Crawford, Y., McCutcheon, K., Tan, C., Ferrara, N., (2010) Cell, 141, pp. 166-177

Ziche, M., Maglione, D., Ribatti, D., Morbidelli, L., Lago, C. T., Battisti, M., Paoletti, I., Persico, M. G., (1997) Lab. Invest., 76, pp. 517-531

Cao, Y., Chen, H., Zhou, L., Chiang, M. K., Anand-Apte, B., Weatherbee, J. A., Wang, Y., Tsang, M. L., (1996) J. Biol. Chem., 271, pp. 3154-3162

Park, J. E., Chen, H. H., Winer, J., Houck, K. A., Ferrara, N., (1994) J. Biol. Chem., 269, pp. 25646-25654

Yang, Y., Xie, P., Opatowsky, Y., Schlessinger, J., (2010) Proc. Natl. Acad. Sci. U. S. A., 107, pp. 1906-1911

Deleted in proofSoro, S., Orecchia, A., Morbidelli, L., Lacal, P. M., Morea, V., Ballmer-Hofer, K., Ruffini, F., Failla, C. M., (2008) Blood, 111, pp. 3479-3488

Nagy, J.A., Dvorak, A.M., Dvorak, H.F., (2007) Annu. Rev. Pathol., 2, pp. 251-275

Olsson, A.K., Dimberg, A., Kreuger, J., Claesson-Welsh, L., (2006) Nat. Rev. Mol. Cell Biol., 7, pp. 359-371

Christinger, H.W., Fuh, G., De Vos, A.M., Wiesmann, C., (2004) J. Biol. Chem., 279, pp. 10382-10388

Goddard, T.D., Kneller, D.G., (2001) SPARKY, , Version 3, University of California, San Francisco, CA

Masse, J.E., Keller, R., (2005) J. Magn. Reson., 174, pp. 133-151

Herrmann, T., Güntert, P., Wüthrich, K., (2002) J. Mol. Biol., 319, pp. 209-227

Morris, K.F., Johnson, G.S., (1992) J. Am. Chem. Soc., 114, pp. 3139-3141

Maynard, A.J., Sharman, G.J., Searle, M.S., (1998) J. Am. Chem. Soc., 120, pp. 1996-2007

Cochran, A.G., Skelton, N.J., Starovasnik, M.A., (2001) Proc. Natl. Acad. Sci. U.S.A., 98, pp. 5578-5583

Wüthrich, K., (1986) NMRof Proteins and Nucleic Acids, , Wiley, New York

Wishart, D.S., Sykes, B.D., Richards, F.M., (1991) J. Mol. Biol., 222, pp. 311-333

Blanco, F.J., Jiménez, M.A., Pineda, A., Rico, M., Santoro, J., Nieto, J.L., (1994) Biochemistry, 33, pp. 6004-6014

Farmer II, B.T., Constantine, K.L., Goldfarb, V., Friedrichs, M.S., Wittekind, M., Yanchunas Jr., J., Robertson, J.G., Mueller, L., (1996) Nat. Struct. Biol., 3, pp. 995-997

D'Andrea, L.D., Del Gatto, A., De Rosa, L., Romanelli, A., Pedone, C., (2009) Curr. Pharm. Des., 15, pp. 2414-2429

D'Andrea, L.D., Iaccarino, G., Fattorusso, R., Sorriento, D., Carannante, C., Capasso, D., Trimarco, B., Pedone, C., (2005) Proc. Natl. Acad. Sci. U.S.A., 102, pp. 14215-14220

Dudar, G.K., D'Andrea, L.D., Di Stasi, R., Pedone, C., Wallace, J.L., (2008) Am. J. Physiol. Gastrointest. Liver Physiol., 295, pp. G374-G381

Keyt, B.A., Nguyen, H.V., Berleau, L.T., Duarte, C.M., Park, J., Chen, H., Ferrara, N., (1996) J. Biol. Chem., 271, pp. 5638-5646

Leppänen, V.M., Prota, A.E., Jeltsch, M., Anisimov, A., Kalkkinen, N., Strandin, T., Lankinen, H., Alitalo, K., (2010) Proc. Natl. Acad. Sci. U.S.A., 107, pp. 2425-2430

García-Aranda, M.I., Marrero, P., Gautier, B., Martín- Martínez, M., Inguimbert, N., Vidal, M., García-López, M.T., Pérez De Vega, M.J., (2011) Bioorg. Med. Chem., 19, pp. 1978-1986

Vicari, D., Foy, K.C., Liotta, E.M., Kaumaya, P.T., (2011) J. Biol. Chem., 286, pp. 13612-13625. , 2011

Santiveri, C.M., Jiménez, M.A., (2010) Biopolymers, 94, pp. 779-790

Russell, S.J., Blandl, T., Skelton, N.J., Cochran, A.G., (2003) J. Am. Chem. Soc., 125, pp. 388-395

Pastor, M.T., Giménez-Giner, A., Pérez-Payá, E., (2005) ChemBioChem, 6, pp. 1753-1756

Blanco, F., Ramírez-Alvarado, M., Serrano, L., (1998) Curr. Opin. Struct. Biol., 8, pp. 107-111

Park, J.E., Chen, H.H., Winer, J., Houck, K.A., Ferrara, N., (1994) J. Biol. Chem., 269, pp. 25646-25654

Starovasnik, M.A., Christinger, H.W., Wiesmann, C., Champe, M.A., De Vos, A.M., Skelton, N.J., (1999) J. Mol. Biol., 293, pp. 531-544



VEGF receptors have been the target of intense research aimed to develop molecules able to inhibit or stimulate angiogenesis. Based on the x-ray structure of the complex placental growth factor-VEGF receptor 1 D2, we designed a VEGF receptor-binding peptide reproducing the placental growth factor β-hairpin region Gln 87-Val 100 that is involved in receptor recognition. A conformational analysis showed that the designed peptide adopts the expected fold in pure water. Moreover, a combination of NMR interaction analysis and cell binding studies were used to demonstrate that the peptide targets VEGF receptors. The VEGF receptor 1 D2-interacting residues were characterized at the molecular level, and they correspond to the residues recognizing the placental growth factor sequence Gln 87-Val 100. Finally, the peptide biological activity was characterized in vitro and in vivo, and it showed a VEGF-like behavior. Indeed, the peptide activated VEGF-dependent intracellular pathways, induced endothelial cell proliferation and rescue from apoptosis, and promoted angiogenesis in vivo. This compound is one of the few peptides known with proangiogenic activity, which makes it a candidate for the development of a novel peptide-based drug for medical applications in therapeutic angiogenesis. © 2011 by The American Society for Biochemistry and Molecular Biology, Inc.

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Zannetti A, Iommelli F, Speranza A, Salvatore M, Del Vecchio S
* 3'-deoxy-3'-18F-fluorothymidine PET/CT to guide therapy with epidermal growth factor receptor antagonists and Bcl-xL inhibitors in non-small cell lung cancer (164 visite)
J Nucl Med (ISSN: 1535-5667, 0161-5505, 1535-5667electronic), 2012 Mar 1; 53(3): 443-450.
Impact Factor: 5.774
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Cirillo G, Colangelo AM, Bianco MR, Cavaliere C, Zaccaro L, Sarmientos P, Alberghina L, Papa M
* BB14, a Nerve Growth Factor (NGF)-like peptide shown to be effective in reducing reactive astrogliosis and restoring synaptic homeostasis in a rat model of peripheral nerve injury (105 visite)
Biotechnology Advances (ISSN: 0734-9750), 2012 Jan; 30(1): 223-232.
Impact Factor: 9.599
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Lanzillo R, Di Somma C, Quarantelli M, Ventrella G, Gasperi M, Prinster A, Vacca G, Pivonello C, Orefice G, Colao A, Morra VB
* Insulin-like growth factor (IGF)-I and IGF-binding protein-3 serum levels in relapsing-remitting and secondary progressive multiple sclerosis patients (115 visite)
Eur J Neurol (ISSN: 1351-5101, 1468-1331electronic), 2011 Dec; 18(12): 1402-1406.
Impact Factor: 3.692
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Travaglia A, Arena G, Fattorusso R, Isernia C, La Mendola D, Malgieri G, Nicoletti VG, Rizzarelli E
* The inorganic perspective of nerve growth factor: interactions of Cu2+ and Zn2+ with the N-terminus fragment of nerve growth factor encompassing the recognition domain of the TrkA receptor (119 visite)
Chemistry (ISSN: 1521-3765, 0947-6539, 1521-3765electronic), 2011 Mar 21; 17(13): 3726-3738.
Impact Factor: 5.925
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Basile A, Del Gatto A, Diana D, Di Stasi R, Falco A, Festa M, Rosati A, Barbieri A, Franco R, Arra C, Pedone C, Fattorusso R, Turco MC, D'Andrea LD
* Characterization of a designed vascular endothelial growth factor receptor antagonist helical peptide with antiangiogenic activity in vivo (126 visite)
J Med Chem (ISSN: 1520-4804, 0022-2623, 0022-2623print), 2011 Mar 10; 54(5): 1391-1400.
Impact Factor: 5.248
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Cirillo G, Bianco MR, Colangelo AM, Cavaliere C, Daniele DL, Zaccaro L, Alberghina L, Papa M
* Reactive astrocytosis-induced perturbation of synaptic homeostasis is restored by nerve growth factor (119 visite)
Neurobiology Of Disease (ISSN: 0969-9961), 2011 Mar; 41(3): 630-639.
Impact Factor: 5.403
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Ciccarelli M, Sorriento D, Cipolletta E, Santulli G, Fusco A, Zhou R-H, Eckhart AD, Peppel K, Koch WJ, Trimarco B, Iaccarino G
* Impaired neoangiogenesis in β2-adrenoceptor gene-deficient mice: Restoration by intravascular human β2-adrenoceptor gene transfer and role of NFkB and CREB transcription factors (103 visite)
Br J Pharmacol British Journal Of Pharmacology (ISSN: 0007-1188), 2011; 162(3): 712-721.
Impact Factor: 4.409
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La Mendola D, Magrì A, Vagliasindi LI, Hansson Ö, Bonomo RP, Rizzarelli E
* Copper(II) complex formation with a linear peptide encompassing the putative cell binding site of angiogenin (106 visite)
Dalton Trans (ISSN: 1477-9234, 1477-9226, 1477-9234electronic), 2010 Nov 28; 39(44): 10678-10684.
Impact Factor: 3.647
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D'Andrea LD, Romanelli A, Di Stasi R, Pedone C
* Bioinorganic aspects of angiogenesis (115 visite)
Dalton Trans (ISSN: 1477-9234, 1477-9226, 1477-9234electronic), 2010 Sep 7; 39(33): 7625-7636.
Impact Factor: 3.647
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Gautier B, Goncalves V, Diana D, Di Stasi R, Teillet F, Lenoir C, Huguenot F, Garbay C, Fattorusso R, D'Andrea LD, Vidal M, Inguimbert N
* Biochemical and Structural Analysis of the Binding Determinants of a Vascular Endothelial Growth Factor Receptor Peptidic Antagonist (105 visite)
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2010 Jun 10; 53(11): 4428-4440.
Impact Factor: 5.207
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Alberobello AT, D'Esposito V, Marasco D, Doti N, Ruvo M, Bianco R, Tortora G, Esposito I, Fiory F, Miele C, Beguinot F, Formisano P
* Selective Disruption of Insulin-like Growth Factor-1 (IGF-1) Signaling via Phosphoinositide-dependent Kinase-1 Prevents the Protective Effect of IGF-1 on Human Cancer Cell Death (104 visite)
J Biol Chem Journal Of Biological Chemistry (ISSN: 0021-9258, 1083-351x), 2010 Feb 26; 285(9): 6563-6572.
Impact Factor: 5.328
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Lanzillo R, Di Somma MC, Quarantelli M, Ventrella G, Prinster A, Vacca G, Orefice G, Colao AM, Morra VB
* Serum levels of insulin-like growth factor-1 and insulin-like growth factor binding protein-3 in relapsing and secondary progressive IFN beta treated MS patients (83 visite)
Journal Of The Neurological Sciences (ISSN: 0022-510x), 2009 Oct; 285: N/D-N/D.
Impact Factor: 2.324
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Lanzillo R, Di Somma C, Quarantelli M, Gasperi M, Ventrella G, Prinster A, Vacca G, Orefice G, Colao A, Morra VB
* Serum levels of insulin like growth factor-1 and insulin like growth factor binding protein-3 in relapsing and secondary progressive multiple sclerosis (126 visite)
Mult Scler (ISSN: 1352-4585, 1477-0970, 1352-4585linking), 2009 Sep; 15(9): 1402-1406.
Impact Factor: 3.279
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D'Andrea LD, Del Gatto A, De Rosa L, Romanelli A, Pedone C
* Peptides targeting angiogenesis related growth factor receptors (13882 visite)
Curr Pharm Des Current Pharmaceutical Design (ISSN: 1873-4286, 1381-6128), 2009 Jul; 15(21): 2414-2429.
Impact Factor: 4.414
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Kaczmarek K, Farina B, Zubrzak P, Jankowski S, Zimecki M, Suder P, Benedetti E, Fattorusso R, Saviano M, Zabrocki J
* Synthesis, conformational analysis and immunological activity of β3Phe-substituted Cyclolinopeptide A analogues (111 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Mar; 15(3): 166-174.
Impact Factor: 1.807
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Merlino A, Vergara A, Sica F, Mazzarella L
* The bis-histidyl complex in hemoproteins: A detailed conformational analysis of database protein structures and the case of Antarctic fish hemoglobins (120 visite)
Marine Genomics (ISSN: 1874-7787), 2009 Mar; 2(1): 51-56.
Impact Factor: 1.2
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Cittadini A, Monti MG, Castiello MC, D'Arco E, Galasso G, Sorriento D, Saldamarco L, De Paulis A, Napoli R, Iaccarino G, Saccà L
* Insulin-like growth factor-1 protects from vascular stenosis and accelerates re-endothelialization in a rat model of carotid artery injury (107 visite)
J Thromb Haemost Journal Of Thrombosis And Haemostasis (ISSN: 1538-7933), 2009; 7(11): 1920-1928.
Impact Factor: 6.069
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Ponticelli S, Marasco D, Tarallo V, Albuquerque RJC, Mitola S, Takeda A, Stassen J, Presta M, Ambati J, Ruvo M, De Falco S
* Modulation of Angiogenesis by a Tetrameric Tripeptide That Antagonizes Vascular Endothelial Growth Factor Receptor (112 visite)
J Biol Chem Journal Of Biological Chemistry (ISSN: 0021-9258, 1083-351x), 2008 Dec 5; 283(49): 34250-34259.
Impact Factor: 5.52
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Dudar GK, D'Andrea LD, Di Stasi R, Pedone C, Wallace JL
* A vascular endothelial growth factor mimetic accelerates gastric ulcer healing in an iNOS-dependent manner (142 visite)
Am J Physiol Gastrointest Liver Physiol American Journal Of Physiology Gastrointestinal And Liver Physiology (ISSN: 0193-1857), 2008 Sep; 295(2): G374-G374.
Impact Factor: 3.587
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Ponticelli S, Takeda A, Mitola S, Stassen J, Presta M, Ambati J, Ruvo M, De Falco S, Marasco D
* Angiogenesis modulation: identification of tetrameric tripeptide as inhibitor of VEGFR-1 by the screening of peptide combinatiorial libraries (108 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2008 Sep; 14(8): N/D-N/D.
Impact Factor: 1.654
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Di Stasi R, Capasso D, Diana D, Fattorusso R, Pedone C, D'Andrea LD
* Vascular Endothelial Growth Factor (VEGF) and its receptors: key regulators of angiogenesis (93 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2008 Sep; 14(8): N/D-N/D.
Impact Factor: 1.654
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Romano S, Mallardo M, Chiurazzi F, Bisogni R, D'Angelillo A, Liuzzi R, Compare G, Romano MF
* The effect of FK506 on transforming growth factor beta signaling and apaptosis in chronic lymphocytic leukemia B cells (98 visite)
Haematologica (ISSN: 0390-6078, 0006-4971, 0006-6497), 2008 Jul; 93(7): 1039-1048.
Impact Factor: 5.978
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Colangelo AM, Bianco MR, Vitagliano L, Cavaliere C, Cirillo G, De Gioia L, Diana D, Colombo D, Redaelli C, Zaccaro L, Morelli G, Papa M, Sarmientos P, Alberghina L, Martegani E
* A New Nerve Growth Factor (ngf)-Mimetic Peptide Active On Neuropathic Pain In Rats (142 visite)
Journal Of Neuroscience (ISSN: 0270-6474, 0270-0647), 2008 Mar 12; 28(11): 2698-2709.
Impact Factor: 7.452
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Migliore T, Parrella LS, Caputi A, Silvestri N, Romano R, Pace L, Imbriaco M, Losi MA, Betocchi S
* Pathogenesis of hypertrophic cardiomyopathy. Impact of growth factors on left ventricular anatomy (108 visite)
Minerva Cardioangiol (ISSN: 0026-4725), 2008 Feb; 56(1): 13-20.
Impact Factor: 0.481
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Diana D, Ziaco B, Colombo G, Scarabelli G, Romanelli A, Fedone C, Fattorusso R, D'Andrea LD
* Structural determinants of the unusual helix stability of a de novo engineered vascular endothelial growth factor (VEGF) mimicking peptide (121 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2008; 14(14): 4164-4166.
Impact Factor: 5.454
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Bianco MR, Cirillo G, Cavaliere C, Colangelo AM, Vitagliano L, Morelli G, Sarmientos P, Martegani E, Alberghina L, Papa M
* A new Nerve Growth Factor (NGF)-mimetic peptide reduces gliosis and is active on neuropathic pain in rats (113 visite)
Neuron Glia Biology (ISSN: 1740-925x), 2007; 2: N/D-N/D.
Impact Factor: 6.636
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D'Andrea LD, Del Gatto A, Pedone C, Benedetti E
* Peptide-based molecules in angiogenesis (151 visite)
Chem Biol Drug Des Chemical Biology And Drug Design (ISSN: 1747-0277, 1747-0285), 2006 Feb; 67(2): 115-126.
Impact Factor: 2.507
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Del Gatto A, D'Andrea LD, Zaccaro L, Saviano M, Pedone C, Benedetti E
* Engineering Peptides In Angiogenesis (121 visite)
Biopolymers, 2006; 0: 215-216.
Impact Factor: 2.288
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D'Andrea LD, Iaccarino G, Fattorusso R, Sorriento D, Carannante C, Capasso D, Trimarco B, Pedone C
* Targeting angiogenesis: Structural characterization and biological properties of a de novo engineered VEGF mimicking peptide (145 visite)
Proc Natl Acad Sci U S A (ISSN: 0027-8424, 1091-6490, 0027-8424print), 2005 Oct 4; 102(40): 14215-14220.
Impact Factor: 10.231
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Vacatello M, D'Auria G, Falcigno L, Dettin M, Gambaretto R, Di Bello C, Paolillo L
* Conformational Analysis Of Novel Heparin Binding Peptides (163 visite)
Biomaterials (ISSN: 0142-9612, 1878-5905electronic), 2005 Jun; 26(16): 3207-3214.
Impact Factor: 4.698
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Saviano M, Isernia C, Bassarello C, Di Lello P, Galdiero S, Mierke DF, Benedetti E, Pedone C
* Conformational analysis by NMR and distance geometry techniques of a peptide mimetic of the third helix of the Antennapedia homeodomain (116 visite)
J Pept Res (ISSN: 1397-002x), 2005 Feb; 65(2): 200-208.
Impact Factor: 1.741
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Iaccarino G, Ciccarelli M, Sorriento D, Galasso G, Campanile A, Santulli G, Cipolletta E, Cerullo V, Cimini V, Altobelli GG, Piscione F, Priante O, Pastore L, Chiariello M, Salvatore F, Koch WJ, Trimarco B
* Ischemic neoangiogenesis enhanced by β2-adrenergic receptor overexpression: A novel role for the endothelial adrenergic system (110 visite)
Circ Res (ISSN: 0009-7330, 1524-4571electronic), 2005; 97(11): 1182-1189.
Impact Factor: 9.408
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Langella E, Rega N, Improta R, Crescenzi O, Barone V
* Conformational analysis of the tyrosine dipeptide analogue in the gas phase and in aqueous solution by a density functional/continuum solvent model (106 visite)
J Comput Chem (ISSN: 0192-8651, 1096-987xelectronic), 2002 Apr 30; 23(6): 650-661.
Impact Factor: 2.931
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Colao A, Cuocolo A, Marzullo P, Nicolai E, Ferone D, Morte A, Pivonello R, Salvatore M, Lombardi G
* Is the acromegalic cardiomyopathy reversible? Effect of 5-year normalization of growth hormone and insulin-like growth factor I levels on cardiac performance (93 visite)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2001 Apr; 86(4): 1551-1557.
Impact Factor: 5.16
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Lombardi G, Colao A, Cuocolo A, Longobardi S, Di Somma C, Orio F, Merola B, Nicolai E, Salvatore M
Cardiological aspects of growth hormone and insulin-like growth factor- (91 visite)
J Pediatr Endocrinol Metab (ISSN: 0334-018x), 1997 Nov; 10(6): 553-560.
Impact Factor: 0.481
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Del Vecchio S, Stoppelli MP, Carriero MV, Fonti R, Massa O, Li PY, Botti G, Cerra M, D'Aiuto G, Esposito G, Salvatore M
IN-VITRO RECEPTOR IMAGING FOR CHARACTERIZATION OF HUMAN SOLID TUMORS (98 visite)
Nuclear Medicine And Biology (ISSN: 0883-2897, 0969-8051), 1994 Jul; 21(5): 771-774.
Impact Factor: 1.042
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Correale P, Caraglia M, Pepe S, Ricciardi B, Barile C, Montagnani S, Pacelli R, Bianco A, Tagliaferri P
PHORBOL 12-MYRISTATE 13-ACETATE (PMA) INDUCES NEUROENDOCRINE-LIKE DIFFERENTIATION AND REVERSES DOXORUBICIN-RESISTANCE OF HUMAN COLON-CARCINOMA CELLS IN-VITRO (70 visite)
Int J Oncol (ISSN: 1019-6439, 1791-2423electronic, 1019-6439linking), 1994 Feb; 4(2): 423-427.
Impact Factor: 1.181
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Caraglia M, Tagliaferri P, Correale P, Genua G, Pinto A, Del Vecchio S, Esposito G, Bianco AR
CYTOSINE-ARABINOSIDE INCREASES THE BINDING OF I-125 LABELED EPIDERMAL GROWTH-FACTOR AND I-125 TRANSFERRIN AND ENHANCES THE IN-VITRO TARGETING OF HUMAN TUMOR-CELLS WITH ANTI-(GROWTH FACTOR-RECEPTOR) MAB (115 visite)
Cancer Immunology Immunotherapy (ISSN: 0340-7004), 1993 Sep; 37(3): 150-156.
Impact Factor: 1.269
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Maglione D, Guerriero V, Viglietto G, Ferraro MG, Aprelikova O, Alitalo K, Del Vecchio S, Lei KJ, Chou JY, Persico MG
Two alternative mRNAs coding for the angiogenic factor, placenta growth factor (PlGF), are transcribed from a single gene of chromosome 14 (120 visite)
Oncogene (ISSN: 0950-9232, 1476-5594), 1993; 8(4): 925-931.
Impact Factor: 6.772
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61 Records (55 escludendo Abstract e Conferenze).
Impact factor totale: 256.553 (238.473 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 267.12 (251.207 escludendo Abstract e Conferenze).







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