Simultaneous non-functioning neuroendocrine carcinoma of the pancreas and extra-hepatic cholangiocarcinoma. A case of early diagnosis and favorable post-surgical outcome
Simultaneous non-functioning neuroendocrine carcinoma of the pancreas and extra-hepatic cholangiocarcinoma. A case of early diagnosis and favorable post-surgical outcome(94 visite) Maurea S, Corvino A, Imbriaco M, Avitabile G, Mainenti P, Camera L, Galizia G, Salvatore M
Jop (ISSN: 1590-8577, 1590-0857), 2011 May 6; 12(3): 255-258.
Parole chiave: Diagnostic Imaging, Magnetic Resonance Imaging, Multiple Primary, Neoplasms, Chromogranin A, Synaptophysin, Abdominal Drainage, Adult, Article, Artificial Embolism, Bile Duct Carcinoma, Bile Duct Dilatation, Cancer Staging, Case Report, Comorbidity, Contrast Enhancement, Early Diagnosis, End To Side Anastomosis, Endoscopic Retrograde Cholangiopancreatography, Gastrointestinal Hemorrhage, Gastrojejunostomy, Hepatojejunostomy, Histopathology, Human, Human Tissue, Immunocytochemistry, Nuclear Magnetic Resonance Imaging, Pancreas Carcinoma, Pancreaticojejunostomy, Physical Examination, Treatment Outcome, Bile Duct Neoplasms, Extrahepatic, Neuroendocrine, Cholangiocarcinoma, Differential, Middle Aged, Pancreatic Neoplasms, Surgery,
Affiliazioni:
*** IBB - CNR *** Dept. of Biomorphological and Functional Sciences (DSBMF), University Federico II of Napoli (UNINA), Biostructures and Bioimages Institution (IBB), Universit degli Studi di Napoli Federico II, National Research Council (CNR), SDN Foundation (IRCCS), via S. Pansini, 80131 Naples, Italy Divisions of Surgical Oncology, F Magrassi A Lanzara Department of Clinical and Experimental Medicine and Surgery, Second University of Naples School of Medicine, Naples, Italy Department of Biomorphological and Functional Sciences (DSBMF), University Federico II of Napoli (UNINA), Naples, Italy. simone. maurea@unina. it
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CONTEXT: Thanks to the wide use of diagnostic imaging modalities, multiple primary malignancies are being diagnosed more frequently and different associations of malignancies have been reported in this setting. CASE REPORT: In this paper, we describe the case of a patient with non-functioning well-differentiated neuroendocrine carcinoma of the head of the pancreas associated with extra-hepatic cholangiocarcinoma, in which an early diagnosis using magnetic resonance imaging allowed a good outcome. CONCLUSION: The simultaneous association of neuroendocrine pancreatic tumors and cholangiocarcinoma has not yet been described; however, this association should be considered and, due to the high contrast of magnetic resonance imaging, this technique is recommended in such patient in order to reach an accurate diagnosis.
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