CEREBRAL CIRCULATION IN PATIENTS WITH MULTIPLE SCLEROSIS. A COLOR-DOPPLER STUDY OF EXTRACRANIAL ARTERIAL AND VENOUS VESSELS(227 views visite) Cervo A, Caprio MG, Ragucci M, Mancini M
Veins And Lymphatics (ISSN: 2279-7483), 2015; 4(s1): 12-12.
1Department of Advanced Biomedical Sciences, University Federico II, Naples; 2Institute of Biostructure and Bioimaging,National Research Council, Naples, Italy
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CEREBRAL CIRCULATION IN PATIENTS WITH MULTIPLE SCLEROSIS. A COLOR-DOPPLER STUDY OF EXTRACRANIAL ARTERIAL AND VENOUS VESSELS
Background: Recent studies hypothesized Multiple Sclerosis (MS) to be influenced by alterations of cerebral circulation. Objectives: To assess whether there is a relation between MS and cerebral circulation, by quantifying arterial inflow and venous outflow and by measuring carotid wall intima-media thickness (IMT). Methods: 82 MS patients and 53 healthy controls (HC) underwent to bifurcation.Vertebral artery (VA) was examined in the V2-segment.Cerebral Blood Flow (CBF) was calculated as the sum of flow volumes in both ICA and VA. Mean intima-media thickness (IMT) was measured over a segment of the common carotid artery. Cross-sectional areas of J1, J2 and J3 tracts of IJVs and venous blood flow in the J3 tract of IJV and in the most caudal tract of VV were measured. Results: The MS group showed lower IJV blood flow than HC in supine position (258.1 mL/m vs 327.7 mL/m; P=0.025). No difference was found in the VVs flow. No parameters in the upright position were different. No difference was found in prevalence of IJV stenosis between the two groups. No differences between groups were seen in arterial inflow (CBF MS mean and range: 597.7 mL,400.2-821 mL, HC 561.7 mL, 242.2-896.7 mL, P=0.055) and IMT (MS 0.54 mm, 0.42-0.92 mm, HC 0.49 mm, 0.4-1.09 mm; P=0.033). Conclusions: The results indicate an association between abnormal cerebral venous flow and MS. No differences between MS and HC in CBF and carotid IMT were detected.
CEREBRAL CIRCULATION IN PATIENTS WITH MULTIPLE SCLEROSIS. A COLOR-DOPPLER STUDY OF EXTRACRANIAL ARTERIAL AND VENOUS VESSELS
116 Records (89 escludendo Abstract e Conferenze). Impact factor totale: 364.935 (305.589 escludendo Abstract e Conferenze). Impact factor a 5 anni totale: 382.494 (319.205 escludendo Abstract e Conferenze).
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