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Balancing Radiation and Contrast Media Dose in Single-Pass Abdominal Multidetector CT: Prospective Evaluation of Image Quality (138 visite)

Camera L, Romano F, Liccardo I, Liuzzi R, Imbriaco M, Mainenti PP, Pizzuti LM, Segreto S, Maurea S, Brunetti A

Acad Radiol (ISSN: 1076-6332, 1878-4046electronic, 1076-6332linking), 2015 Nov; 22(11): 1419-1426.



Tipo di articolo: Journal Article,

Impact factor: 1.966, Impact factor a 5 anni: 1.945

Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84938703635&partnerID=40&md5=e388667c5dc626a3763afc02d7d22cb8

Parole chiave: Contrast Media, Ct Protocols, Ct Technique, Effective Dose, Image Quality, Abdomen Diagnostic Imaging , Adult , Age Factors , 80 And Over , Contrast Media Administration, Dosage , Female , Humans , Image Enhancement , Middle Aged , Multidetector Computed Tomography Methods , Prospective Studies , Radiation Dosage,

Affiliazioni:

*** IBB - CNR ***
Section of Diagnostic Imaging, Department of Advanced Biomedical Sciences, University Federico II, Via S. Pansini 5, Naples 80131, Italy
Institute of Biostructures and Bioimaging (C.N.R.), University Federico II, Naples, Italy



Riferimenti:

Non disponibile.


RATIONALE AND OBJECTIVES: As both contrast and radiation dose affect the quality of CT images, a constant image quality in abdominal contrast-enhanced multidetector computed tomography (CE-MDCT) could be obtained balancing radiation and contrast media dose according to the age of the patients. MATERIALS AND METHODS: Seventy-two (38 Men; 34 women; aged 20-83 years) patients underwent a single-pass abdominal CE-MDCT. Patients were divided into three different age groups: A (20-44 years); B (45-65 years); and C (>65 years). For each group, a different noise index (NI) and contrast media dose (370 mgI/mL) was selected as follows: A (NI, 15; 2.5 mL/kg), B (NI, 12.5; 2 mL/kg), and C (NI, 10; 1.5 mL/kg). Radiation exposure was reported as dose-length product (DLP) in mGy x cm. For quantitative analysis, signal-to-noise (SNR) and contrast-to-noise (CNR) ratios were calculated for both the liver (L) and the abdominal aorta (A). Statistical analysis was performed with a one-way analysis of variance. Standard imaging criteria were used for qualitative analysis. RESULTS: Although peak hepatic enhancement was 152 +/- 16, 128 +/- 12, and 101 +/- 14 Hounsfield units (P < .001) for groups A, B, and C, respectively, no significant differences were observed in the corresponding SNRL with 9.2 +/- 1.4, 9.1 +/- 1.2, and 9.2 +/- 3. Radiation (mGy x cm) and contrast media dose (mL) administered were 476 +/- 147 and 155 +/- 27 for group A, 926 +/- 291 and 130 +/- 16 for group B, and 1981 +/- 451 and 106 +/- 15 for group C, respectively (P < .001). None of the studies was graded as poor or inadequate by both readers, and the prevalence-adjusted bias-adjusted kappa ranged between 0.48 and 0.93 for all but one criteria. CONCLUSIONS: A constant image quality in CE-MDCT can be obtained balancing radiation and contrast media dose administered to patients of different age.
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Varrone A, Sansone V, Pellecchia MT, Amboni M, Salvatore E, De Michele G, Filla A, Barone P, Pappata S, Salvatore M
* Comparison between a dual-head and a brain-dedicated SPECT system in the measurement of the loss of dopamine transporters with [123I]FP-CIT (119 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2008 Jul; 35(7): 1343-1349.
Impact Factor: 4.532
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Lapi F, Cecchi E, Pedone C, Attanasio F, Banchelli G, Vannacci A, Di Pirro M, Moschini M, Berni V, Matucci R, Cini E, Scalia A, Tendi E, Mugelli A
* Safety aspects of iodinated contrast media related to their physicochemical properties: A pharmacoepidemiology study in two Tuscany hospitals (118 visite)
Eur J Clin Pharmacol Springer Verlag (ISSN: 0031-6970, 1432-1041), 2008 Jul; 64(7): 723-737.
Impact Factor: 2.497
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Takano A, Halldin C, Varrone A, Karlsson P, Sjoholm N, Stubbs JB, Schou M, Airaksinen AJ, Tauscher J, Gulyas B
* Biodistribution and radiation dosimetry of the norepinephrine transporter radioligand (S, S)-[18F]FMeNER-D2: A human whole-body PET study (100 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2008 Mar; 35(3): 630-636.
Impact Factor: 4.532
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Ragozzino A, Lassandro F, De Ritis R, Imbriaco M
* Value of MRI in three patients with major vascular injuries after laparoscopic cholecystectomy (83 visite)
Emergency Radiology (ISSN: 1070-3004), 2007 Nov; 14(6): 443-447.
Impact Factor: 6.214
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Storto G, Pellegrino T, Sorrentino AR, Luongo L, Petretta M, Cuocolo A
* Estimation of coronary flow reserve by sestamibi imaging in type 2 diabetic patients with normal coronary arteries (103 visite)
J Nucl Cardiol (ISSN: 1532-6551, 1071-3581, 1532-6551electronic), 2007 Apr; 14(2): 194-199.
Impact Factor: 2.359
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Berkouk K, Quarantelli M, Prinster A, Landeau B, Alfano B, Baron JC
* Mapping The Relative Contribution Of Gray Matter Activity Versus Volume In Brain Pet. A New Approach (166 visite) (PDF 137 visite)
J Neuroimaging (ISSN: 1051-2284), 2006 Jul; 16(3): 224-235.
Impact Factor: 1.298
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Imbriaco M, Smeraldo D, Liuzzi R, Carrillo F, Cacace G, Vecchione D, Diglio A, Salvatore M
* Multislice CT with single-phase technique in patients with suspected pancreatic cancer (88 visite)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 2006 Mar; 111(2): 159-166.
Impact Factor: 1.368
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Cuocolo A, Acampa W, Imbriaco M, De Luca N, Iovino GL, Salvatore M
* The many ways to myocardial perfusion imaging (204 visite)
Q J Nucl Med Mol Imaging (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2005 Mar; 49(1): 4-18.
Impact Factor: 1.724
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Pace L, Del Vecchio S, Salvatore M
* Technetium 99m sestamibi in multiple myeloma (87 visite)
Radiology (ISSN: 0033-8419, 1527-1315, 1527-1315electronic), 2005 Jan; 234(1): 312-313.
Impact Factor: 5.377
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Pace L, Del Vecchio S, Salvatore M, Walker RC, Angtuaco E, Sethi R, Fassas A, Barlogie B
* Technetium 99m sestamibi in multiple myeloma [3] (multiple letters) (97 visite)
Radiology (ISSN: 0033-8419, 1527-1315, 1527-1315electronic), 2005; 234(1): 312-313.
Impact Factor: 5.377
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Romano M, Amato B, Markabaoui K, Tamburrini O, Salvatore M
* Follow-up of patients with previous vascular interventions: Role of multidetector row computed tomographic angiography of the abdominal aorta and lower extremities [4] (81 visite)
J Cardiovasc Surg (ISSN: 0021-9509), 2004 Feb; 45(1): 89-91.
Impact Factor: 0.8
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Quarantelli M, Berkouk K, Prinster A, Landeau B, Svarer C, Balkay L, Alfano B, Brunetti A, Baron JC, Salvatore M
* Integrated software for the analysis of brain PET/SPECT studies with partial-volume-effect correction (191 visite) (PDF 146 visite)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2004 Feb; 45(2): 192-201.
Impact Factor: 5.362
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Kim KM, Varrone A, Watabe H, Shidahara M, Fujita M, Innis RB, Iida H
* Contribution of scatter and attenuation compensation to SPECT images of nonuniformly distributed brain activities (129 visite)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2003 Apr; 44(4): 512-519.
Impact Factor: 4.899
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Cella L, Lomax A, Miralbell R
* New techniques in hadrontherapy: Intensity modulated proton beams (83 visite)
Phys Med (ISSN: 1120-1797, 1120-1797linking), 2001; 17(SUPPL.1): 100-102.
Impact Factor: 0.556
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Cella L, Lomax A, Miralbell R
* Potential role of intensity modulated proton beams in prostate cancer radiotherapy (86 visite)
Int J Radiat Oncol Biol Phys (ISSN: 0360-3016, 1879-355x, 1879-355xelectronic), 2001; 49(1): 217-223.
Impact Factor: 3.327
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Cirillo LC, Camera L, Della Noce M, Castiglione F, Mazzacca G, Salvatore M
Accuracy of enteroclysis in Crohn's disease of the small bowel: A retrospective study (98 visite)
Eur Radiol (ISSN: 0938-7994, 1432-1084electronic), 2000; 10(12): 1894-1898.
Impact Factor: 1.119
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Acampa W, Cuocolo A, Sullo P, Varrone A, Nicolai E, Pace L, Petretta M, Salvatore M
Direct comparison of technetium 99m-sestamibi and technetium 99m-tetrofosmin cardiac single photon emission computed tomography in patients with coronary artery disease (108 visite)
J Nucl Cardiol (ISSN: 1071-3581, 1532-6551, 1532-6551electronic), 1998 May; 5(3): 265-274.
Impact Factor: 1.336
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Salvatore M, Del Vecchio S
Dynamic imaging: Scintimammography (139 visite)
Eur J Radiol Elsevier Sci Ireland Ltd (ISSN: 0720-048x), 1998 May; 27(SUPPL.2): S259-S259.
Impact Factor: 0.537
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Maurea S, Cuocolo A, Reynolds JC, Neumann RD, Salvatore M
Diagnostic imaging in patients with paragangliomas. Computer tomography, magnetic resonance and MIBG scintigraphy comparison (106 visite)
Q J Nucl Med (ISSN: 1124-3937, 1125-0135), 1996; 40(4): 365-371.
Impact Factor: 2.125
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Maurea S, Lastoria S, Klain M, Brunetti A, Boscaino A, Lupoli G, Salvatore M
Diagnostic evaluation of thyroid involvement by histiocytosis (83 visite)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1994 Feb; 35(2): 263-265.
Impact Factor: 3.491
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68 Records (67 escludendo Abstract e Conferenze).
Impact factor totale: 237.286 (236.749 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 256.893 (254.774 escludendo Abstract e Conferenze).







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