Interaction between AIF and CHCHD4 Regulates Respiratory Chain Biogenesis(170 visite) Hangen E, Féraud O, Lachkar S, Mou H, Doti N, Fimia GM, Lam N-V, Zhu C, Godin I, Muller K, Chatzi A, Nuebel E, Ciccosanti F, Flamant S, Bénit P, Perfettini J-L, Sauvat A, Bennaceur-Griscelli A, Ser-Le Roux K, Gonin P, Tokatlidis K, Rustin P, Piacentini M, Ruvo M, Blomgren K, Kroemer G, Modjtahedi N
Parole chiave: Small Interfering Rna, Thiol Oxidase, Apoptosis, Article, Biogenesis, Breathing, Cell Death, Deletion Mutant, Depletion, Embryo Development, Escherichia Coli, Image Analysis, Immunoprecipitation, Inner Membrane, Isothermal Titration Calorimetry, Membrane Potential, Mitochondrial Targeting Signal, Morphogenesis, Phenotype, Protein Expression, Protein Protein Interaction, Respiratory Chain, Respiratory Function, Stable Transfection,
Affiliazioni:
*** IBB - CNR *** Equipe 11 labellisée par la Ligue Nationale contre le Cancer, Centre de Recherche des Cordeliers, Paris, France INSERM, UMRS 1138, Paris, France Gustave Roussy Comprehensive Cancer Center, Villejuif, France Université Paris Descartes/Paris V, Sorbonne Paris Cité, Paris, France Université Pierre et Marie Curie, Paris, France Université Paris Sud/Paris XI, Kremlin Bicêtre, France INSERM U935, Villejuif, France ESTeam Paris Sud, Stem Cell Core Facility, Institut André Lwoff, Villejuif, France Istituto di Biostrutture e Bioimmagini, CNR, Napoli, Italy Department of Epidemiology and Preclinical Research, National Institute for Infectious Diseases IRCCS L. Spallanzani, Rome, Italy Department of Biological and Environmental Sciences and Technologies (DiSTeBA), University of Salento, Lecce, Italy Center for Brain Repair and Rehabilitation, Institute of Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden INSERM U1009, Villejuif, France Institute of Molecular Cell and Systems Biology, University of Glasgow, Glasgow, United Kingdom INSERM UMR1141, Hôpital Robert Debré, Paris, France Faculté de Médecine Denis Diderot, Université Paris 7, Paris, France Cell Death and Aging Team, Gustave Roussy, Villejuif, France INSERM U1030, Gustave Roussy, Villejuif, France Cell Biology and Metabolomics Platforms, Gustave Roussy Comprehensive Cancer Center, Villejuif, France Laboratoire d'Hématologie, Hôpital Paul Brousse AP-HP, Villejuif, France Animal and Veterinary Resources, Villejuif, France Department of Pediatrics, University of Gothenburg, The Queen Silvia Children's Hospital, Gothenburg, Sweden Karolinska Institute, Department of Women's and Children's Health, Karolinska University Hospital, Stockholm, Sweden Pôle de Biologie, Hôpital Européen Georges Pompidou, AP-HP, Paris, France 1Equipe 11 labellise´ e par la Ligue Nationale contre le Cancer, Centre de Recherche des Cordeliers, 75006 Paris, Fran
Riferimenti:
Allen, S., Balabanidou, V., Sideris, D.P., Lisowsky, T., Tokatlidis, K., Erv1 mediates the Mia40-dependent protein import pathway and provides a functional link to the respiratory chain by shuttling electrons to cytochrome c (2005) J. Mol. Biol., 353, pp. 937-94
Baker, M.J., Mooga, V.P., Guiard, B., Langer, T., Ryan, M.T., Stojanovski, D., Impaired folding of the mitochondrial small TIM chaperones induces clearance by the i-AAA protease (2012) J. Mol. Biol., 424, pp. 227-239
Banci, L., Bertini, I., Cefaro, C., Ciofi-Baffoni, S., Gallo, A., Martinelli, M., Sideris, D.P., Tokatlidis, K., MIA40 is an oxidoreductase that catalyzes oxidative protein folding in mitochondria (2009) Nat. Struct. Mol. Biol., 16, pp. 198-206
Bénit, P., Goncalves, S., Dassa, E.P., Brière, J.J., Rustin, P., The variability of the harlequin mouse phenotype resembles that of human mitochondrial-complex I-deficiency syndromes (2008) PLoS ONE, 3, p. e3208
Berger, I., Ben-Neriah, Z., Dor-Wolman, T., Shaag, A., Saada, A., Zenvirt, S., Raas-Rothschild, A., Elpeleg, O., Early prenatal ventriculomegaly due to an AIFM1 mutation identified by linkage analysis and whole exome sequencing (2011) Mol. Genet. Metab., 104, pp. 517-520
Bihlmaier, K., Mesecke, N., Terziyska, N., Bien, M., Hell, K., Herrmann, J.M., The disulfide relay system of mitochondria is connected to the respiratory chain (2007) J. Cell Biol., 179, pp. 389-395
Brown, D., Yu, B.D., Joza, N., Bénit, P., Meneses, J., Firpo, M., Rustin, P., Martin, G.R., Loss of Aif function causes cell death in the mouse embryo, but the temporal progression of patterning is normal (2006) Proc. Natl. Acad. Sci. USA, 103, pp. 9918-9923
Chacinska, A., Pfannschmidt, S., Wiedemann, N., Kozjak, V., Sanjuán Szklarz, L.K., Schulze-Specking, A., Truscott, K.N., Pfanner, N., Essential role of Mia40 in import and assembly of mitochondrial intermembrane space proteins (2004) EMBO J., 23, pp. 3735-3746
Chacinska, A., Guiard, B., Müller, J.M., Schulze-Specking, A., Gabriel, K., Kutik, S., Pfanner, N., Mitochondrial biogenesis, switching the sorting pathway of the intermembrane space receptor Mia40 (2008) J. Biol. Chem., 283, pp. 29723-29729
Churbanova, I.Y., Sevrioukova, I.F., Redox-dependent changes in molecular properties of mitochondrial apoptosis-inducing factor (2008) J. Biol. Chem., 283, pp. 5622-5631
Dabir, D.V., Leverich, E.P., Kim, S.K., Tsai, F.D., Hirasawa, M., Knaff, D.B., Koehler, C.M., A role for cytochrome c and cytochrome c peroxidase in electron shuttling from Erv1 (2007) EMBO J., 26, pp. 4801-4811
Darshi, M., Trinh, K.N., Murphy, A.N., Taylor, S.S., Targeting and import mechanism of coiled-coil helix coiled-coil helix domain-containing protein 3 (ChChd3) into the mitochondrial intermembrane space (2012) J. Biol. Chem., 287, pp. 39480-39491
de Boer, E., Rodriguez, P., Bonte, E., Krijgsveld, J., Katsantoni, E., Heck, A., Grosveld, F., Strouboulis, J., Efficient biotinylation and single-step purification of tagged transcription factors in mammalian cells and transgenic mice (2003) Proc. Natl. Acad. Sci. USA, 100, pp. 7480-7485
de Felipe, P., Luke, G.A., Hughes, L.E., Gani, D., Halpin, C., Ryan, M.D., E unum pluribus: multiple proteins from a self-processing polyprotein (2006) Trends Biotechnol., 24, pp. 68-75
Di Fonzo, A., Ronchi, D., Lodi, T., Fassone, E., Tigano, M., Lamperti, C., Corti, S., Nizzardo, M., The mitochondrial disulfide relay system protein GFER is mutated in autosomal-recessive myopathy with cataract and combined respiratory-chain deficiency (2009) Am. J. Hum. Genet., 84, pp. 594-604
Feraud, O., Debili, N., Penninger, J.M., Kroemer, G., Cavitation of embryoid bodies requires optimal oxidative phosphorylation and AIF (2007) Cell Death Differ., 14, pp. 385-387
Fischer, M., Horn, S., Belkacemi, A., Kojer, K., Petrungaro, C., Habich, M., Ali, M., Kauff, F., Protein import and oxidative folding in the mitochondrial intermembrane space of intact mammalian cells (2013) Mol. Biol. Cell, 24, pp. 2160-2170
Fraga, H., Bech-Serra, J.J., Canals, F., Ortega, G., Millet, O., Ventura, S., The mitochondrial intermembrane space oxireductase Mia40 funnels the oxidative folding pathway of the cytochrome c oxidase assembly protein Cox19 (2014) J. Biol. Chem., 289, pp. 9852-9864
Ghezzi, D., Sevrioukova, I., Invernizzi, F., Lamperti, C., Mora, M., D'Adamo, P., Novara, F., Zeviani, M., Severe X-linked mitochondrial encephalomyopathy associated with a mutation in apoptosis-inducing factor (2010) Am. J. Hum. Genet., 86, pp. 639-649
Hangen, E., Blomgren, K., Bénit, P., Kroemer, G., Modjtahedi, N., Life with or without AIF (2010) Trends Biochem. Sci., 35, pp. 278-287
Hangen, E., De Zio, D., Bordi, M., Zhu, C., Dessen, P., Caffin, F., Lachkar, S., Benard, J., A brain-specific isoform of mitochondrial apoptosis-inducing factor: AIF2 (2010) Cell Death Differ., 17, pp. 1155-1166
Hofmann, S., Rothbauer, U., Mühlenbein, N., Baiker, K., Hell, K., Bauer, M.F., Functional and mutational characterization of human MIA40 acting during import into the mitochondrial intermembrane space (2005) J. Mol. Biol., 353, pp. 517-528
Jensen, M.B., Jasper, H., Mitochondrial proteostasis in the control of aging and longevity (2014) Cell Metab., 20, pp. 214-225
Joza, N., Susin, S.A., Daugas, E., Stanford, W.L., Cho, S.K., Li, C.Y., Sasaki, T., Ravagnan, L., Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death (2001) Nature, 410, pp. 549-554
Koch, J.R., Schmid, F.X., Mia40 targets cysteines in a hydrophobic environment to direct oxidative protein folding in the mitochondria (2014) Nat. Commun., 5, p. 3041
Li, X., Zhao, X., Fang, Y., Jiang, X., Duong, T., Fan, C., Huang, C.C., Kain, S.R., Generation of destabilized green fluorescent protein as a transcription reporter (1998) J. Biol. Chem., 273, pp. 34970-34975
Maté, M.J., Ortiz-Lombardía, M., Boitel, B., Haouz, A., Tello, D., Susin, S.A., Penninger, J., Alzari, P.M., The crystal structure of the mouse apoptosis-inducing factor AIF (2002) Nat. Struct. Biol., 9, pp. 442-446
Milenkovic, D., Ramming, T., Müller, J.M., Wenz, L.S., Gebert, N., Schulze-Specking, A., Stojanovski, D., Chacinska, A., Identification of the signal directing Tim9 and Tim10 into the intermembrane space of mitochondria (2009) Mol. Biol. Cell, 20, pp. 2530-2539
Murray, P., Edgar, D., The regulation of embryonic stem cell differentiation by leukaemia inhibitory factor (LIF) (2001) Differentiation, 68, pp. 227-234
Naoé, M., Ohwa, Y., Ishikawa, D., Ohshima, C., Nishikawa, S., Yamamoto, H., Endo, T., Identification of Tim40 that mediates protein sorting to the mitochondrial intermembrane space (2004) J. Biol. Chem., 279, pp. 47815-47821
Norberg, E., Karlsson, M., Korenovska, O., Szydlowski, S., Silberberg, G., Uhlén, P., Orrenius, S., Zhivotovsky, B., Critical role for hyperpolarization-activated cyclic nucleotide-gated channel 2 in the AIF-mediated apoptosis (2010) EMBO J., 29, pp. 3869-3878
Otera, H., Ohsakaya, S., Nagaura, Z., Ishihara, N., Mihara, K., Export of mitochondrial AIF in response to proapoptotic stimuli depends on processing at the intermembrane space (2005) EMBO J., 24, pp. 1375-1386
Parrish, J.Z., Xue, D., Functional genomic analysis of apoptotic DNA degradation in C. elegans (2003) Mol. Cell, 11, pp. 987-996
Pfanner, N., van der Laan, M., Amati, P., Capaldi, R.A., Caudy, A.A., Chacinska, A., Darshi, M., Icho, T., Uniform nomenclature for the mitochondrial contact site and cristae organizing system (2014) J. Cell Biol., 204, pp. 1083-1086
Pospisilik, J.A., Knauf, C., Joza, N., Benit, P., Orthofer, M., Cani, P.D., Ebersberger, I., Neely, G., Targeted deletion of AIF decreases mitochondrial oxidative phosphorylation and protects from obesity and diabetes (2007) Cell, 131, pp. 476-491
Qi, Y., Tian, X., Liu, J., Han, Y., Graham, A.M., Simon, M.C., Penninger, J.M., Li, S., Bnip3 and AIF cooperate to induce apoptosis and cavitation during epithelial morphogenesis (2012) J. Cell Biol., 198, pp. 103-114
Rinaldi, C., Grunseich, C., Sevrioukova, I.F., Schindler, A., Horkayne-Szakaly, I., Lamperti, C., Landouré, G., Bönnemann, C., Cowchock syndrome is associated with a mutation in apoptosis-inducing factor (2012) Am. J. Hum. Genet., 91, pp. 1095-1102
Sideris, D.P., Petrakis, N., Katrakili, N., Mikropoulou, D., Gallo, A., Ciofi-Baffoni, S., Banci, L., Tokatlidis, K., A novel intermembrane space-targeting signal docks cysteines onto Mia40 during mitochondrial oxidative folding (2009) J. Cell Biol., 187, pp. 1007-1022
Susin, S.A., Lorenzo, H.K., Zamzami, N., Marzo, I., Snow, B.E., Brothers, G.M., Mangion, J., Loeffler, M., Molecular characterization of mitochondrial apoptosis-inducing factor (1999) Nature, 397, pp. 441-446
Szklarczyk, R., Wanschers, B.F., Nabuurs, S.B., Nouws, J., Nijtmans, L.G., Huynen, M.A., NDUFB7 and NDUFA8 are located at the intermembrane surface of complex I (2011) FEBS Lett., 585, pp. 737-743
Weis, B.L., Schleiff, E., Zerges, W., Protein targeting to subcellular organelles via MRNA localization (2013) Biochim. Biophys. Acta, 1833, pp. 260-273
Yang, J., Staples, O., Thomas, L.W., Briston, T., Robson, M., Poon, E., Simões, M.L., Ahmed, A., Human CHCHD4 mitochondrial proteins regulate cellular oxygen consumption rate and metabolism and provide a critical role in hypoxia signaling and tumor progression (2012) J. Clin. Invest., 122, pp. 600-611
Ye, H., Cande, C., Stephanou, N.C., Jiang, S., Gurbuxani, S., Larochette, N., Daugas, E., Wu, H., DNA binding is required for the apoptogenic action of apoptosis inducing factor (2002) Nat. Struct. Biol., 9, pp. 680-684
Petraglia F, Singh AA, Carafa V, Nebbioso A, Conte M, Scisciola L, Valente S, Baldi A, Mandoli A, Petrizzi VB, Ingenito C, De Falco S, Cicatiello V, Apicella I, Janssen-megens EM, Kim B, Yi G, Logie C, Heath S, Ruvo M, Wierenga ATJ, Flicek P, Yaspo ML, Della Valle V, Bernard O, Tomassi S, Novellino E, Feoli A, Sbardella G, Gut I, Vellenga E, Stunnenberg HG, Mai A, Martens JHA, Altucci L * Combined HAT/EZH2 modulation leads to cancer-selective cell death(64 visite) Oncotarget (ISSN: 1949-2553electronic, 1949-2553linking), 2018 May 22; 9(39): 25630-25646. Impact Factor:5.008 DettagliEsporta in BibTeXEsporta in EndNote
Kim YH, Shin SW, Pellicano R, Fagoonee S, Choi IJ, Kim YI, Park B, Choi JM, Kim SG, Choi J, Park JY, Oh S, Yang HJ, Lim JH, Im JP, Kim JS, Jung HC, Ponzetto A, Figura N, Malfertheiner P, Choi IJ, Kook MC, Kim YI, Cho SJ, Lee JY, Kim CG, Park B, Nam BH, Bae SE, Choi KD, Choe J, Kim SO, Na HK, Choi JY, Ahn JY, Jung KW, Lee J, Kim DH, Chang HS, Song HJ, Lee GH, Jung HY, Seta T, Takahashi Y, Noguchi Y, Shikata S, Sakai T, Sakai K, Yamashita Y, Nakayama T, Leja M, Park JY, Murillo R, Liepniece-karele I, Isajevs S, Kikuste I, Rudzite D, Krike P, Parshutin S, Polaka I, Kirsners A, Santare D, Folkmanis V, Daugule I, Plummer M, Herrero R, Tsukamoto T, Nakagawa M, Kiriyama Y, Toyoda T, Cao X, Corral JE, Mera R, Dye CW, Morgan DR, Lee YC, Lin JT, Garcia Martin R, Matia Cubillo A, Lee SH, Park JM, Han YM, Ko WJ, Hahm KB, Leontiadis GI, Ford AC, Ichinose M, Sugano K, Jeong M, Park JM, Han YM, Park KY, Lee DH, Yoo JH, Cho JY, Hahm KB, Bang CS, Baik GH, Shin IS, Kim JB, Suk KT, Yoon JH, Kim YS, Kim DJ * Helicobacter pylori Eradication for Prevention of Metachronous Recurrence after Endoscopic Resection of Early Gastric Cancer(42 visite) N Engl J Med (ISSN: 0028-4793, 0028-4793linking, 1533-4406electronic), 2015 Jun; 30642104201566393291: 749-756. Impact Factor:59.558 DettagliEsporta in BibTeXEsporta in EndNote
Ntziachristos V, Cuénod CA, Fournier L, Balvay D, Pradel C, Siauve N, Clement O, Jouannot E, Lucidarme O, Vecchio SD, Salvatore M, Law B, Tung C-H, Jain RK, Fukumura D, Munn LL, Brown EB, Schellenberger E, Montet X, Weissleder R, Clerck ND, Postnov A * Tumor Imaging(146 visite) Textbook Of In Vivo Imaging In Vertebrates (ISSN: 9780-4700), 2007 Jul 16; 1: 277-309. Impact Factor:1.148 DettagliEsporta in BibTeXEsporta in EndNote
135 Records (115 escludendo Abstract e Conferenze). Impact factor totale: 640.119 (559.953 escludendo Abstract e Conferenze). Impact factor a 5 anni totale: 645.054 (560.534 escludendo Abstract e Conferenze).
ibb.cnr.it