Home Research Locations About us Organization Staff Contacts Education Login Documents IT
Projects highlights

INCIPIT

ISTAPCA (874 views)

Euro-BioImaging

Instruct-IT

Fondazione Veronesi

Fondo Europeo Pesca (282 views)

 INMiND (943 views)

 PRIN (1047 views)

 eHealthNet (870 views)

  Ponrec (826 views)

MFAG Grant (896 views)

(42 views)


Links

 |<  < >  >| 

    Export to BibTeX    Export to EndNote

UV-Induced Proton Transfer between DNA Strands (71 views) (PDF restricted 58 views)

Zhang Y, de La Harpe K, Beckstead AA, Improta R, Kohler B

J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126), 2015 Jun 10; 137(22): 7059-7062.

Abstract
UV radiation creates excited states in DNA that lead to mutagenic photoproducts. Photoexcitation of single-stranded DNA can transfer an electron between stacked bases, but the fate of excited states in the double helix has been intensely debated. Here, photoinduced interstrand proton transfer (PT) triggered by intrastrand electron transfer (ET) is detected for the first time by time-resolved vibrational spectroscopy and quantum mechanical calculations. Long-lived excited states are shown to be oppositely charged base pair radical ions. In two of the duplexes, the base pair radical anions are present as tautomers formed by interstrand PT. Charge recombination occurs on the picosecond time scale preventing the accumulation of damaging radicals or mutagenic tautomers. © 2015 American Chemical Society.

Affiliations ▼
*** IBB - CNR Affiliation

Department of Chemistry and Biochemistry, Montana State University, Bozeman, MT, United States

Department of Physics, United States Air Force Academy, USAF AcademyCO, United States

Consiglio Nationale Delle Ricerche, Istituto di Biostrutture e Bioimmagini, Via Mezzocannone 16, Naples, Italy

daggerDepartment of Chemistry and Biochemistry, Montana State University, Bozeman, Montana 59717, United States., double daggerDepartment of Physics, United States Air Force Academy, USAF Academy, Colorado 80840, United States., section signConsiglio Nationale delle Ricerche, Istituto di Biostrutture e Bioimmagini, Via Mezzocannone 16, 80136 Naples, Italy.,

Details ▼
Impact factor: 13.038, 5-year impact factor: 12.376

Paper type: Journal Article, Research Support, Non-U. S. Gov'T, Non-P. H. S.,

Keywords: Excited States, Free Radical Reactions, Proton Transfer, Quantum Theory, Vibrations (mechanical), Charge Recombinations, Electron Transfer, Mutagenic Tautomers, Photo-Induced, Picosecond Time Scale, Quantum-Mechanical Calculation, Radical Anions, Single-Stranded Dna, Double Stranded Dna, Acid Dissociation Constant, Article, Base Pairing, Dna Helix, Dna Strand, Electron Transport, Nucleotide Sequence, Proton Transport, Quantum Mechanics, Spectroscopy, Ultraviolet Radiation,

Url: http://www.scopus.com/inward/record.url?eid=2-s2.0-84935863950&partnerID=40&md5=e5ec12d4c827729bc7c5d5879ddcd610

References ▼
Crespo-Hernández, C.E., Cohen, B., Kohler, B., (2005) Nature, 436, p. 114

Markovitsi, D., Gustavsson, T., Vayá, I., (2010) J. Phys. Chem. Lett., 1, p. 3271

Bucher, D.B., Schlueter, A., Carell, T., Zinth, W., (2014) Angew. Chem., Int. Ed., 53

Doorley, G.W., Wojdyla, M., Watson, G.W., Towrie, M., Parker, A.W., Kelly, J.M., Quinn, S.J., (2013) J. Phys. Chem. Lett., 4, p. 2739

Bucher, D.B., Pilles, B.M., Carell, T., Zinth, W., (2014) Proc. Natl. Acad. Sci. U.S.A., 111, p. 4369

Zhang, Y., Dood, J., Beckstead, A.A., Li, X.B., Nguyen, K.V., Burrows, C.J., Improta, R., Kohler, B., (2014) Proc. Natl. Acad. Sci. U.S.A., 111

De La Harpe, K., Kohler, B., (2011) J. Phys. Chem. Lett., 2, p. 133

Sobolewski, A.L., Domcke, W., (2004) Phys. Chem. Chem. Phys., 6, p. 2763

Perun, S., Sobolewski, A.L., Domcke, W., (2006) J. Phys. Chem. A, 110, p. 9031

Steenken, S., (1992) Free Radical Res. Commun., 16, p. 349

Kumar, A., Sevilla, M.D., (2010) Chem. Rev., 110, p. 7002

Kobayashi, K., Tagawa, S., (2003) J. Am. Chem. Soc., 125

Yamagami, R., Kobayashi, K., Tagawa, S., (2008) J. Am. Chem. Soc., 130

Yates, B.F., Bouma, W.J., Radom, L., (1984) J. Am. Chem. Soc., 106, p. 5805

Huynh, M.H.V., Meyer, T.J., (2007) Chem. Rev., 107, p. 5004

Colson, A.-O., Besler, B., Close, D.M., Sevilla, M.D., (1992) J. Phys. Chem., 96, p. 661

Bertran, J., Oliva, A., Rodríguez-Santiago, L., Sodupe, M., (1998) J. Am. Chem. Soc., 120, p. 8159

Li, X., Cai, Z., Sevilla, M.D., (2001) J. Phys. Chem. B, 105

Zhao, Y., Truhlar, D.G., (2008) Acc. Chem. Res., 41, p. 157

Krummel, A.T., Mukherjee, P., Zanni, M.T., (2003) J. Phys. Chem. B, 107, p. 9165

Peng, C.S., Jones, K.C., Tokmakoff, A., (2011) J. Am. Chem. Soc., 133

Doorley, G.W., McGovern, D.A., George, M.W., Towrie, M., Parker, A.W., Kelly, J.M., Quinn, S.J., (2009) Angew. Chem., Int. Ed., 48, p. 123

Ko, C., Hammes-Schiffer, S., (2013) J. Phys. Chem. Lett., 4, p. 2540

Kuimova, M.K., Cowan, A.J., Matousek, P., Parker, A.W., Sun, X.Z., Towrie, M., George, M.W., (2006) Proc. Natl. Acad. Sci. U.S.A., 103, p. 2150

Parker, A.W., Lin, C.Y., George, M.W., Towrie, M., Kuimova, M.K., (2010) J. Phys. Chem. B, 114, p. 3660

Lange, A.W., Herbert, J.M., (2009) J. Am. Chem. Soc., 131, p. 3913

Chen, J., Thazhathveetil, A.K., Lewis, F.D., Kohler, B., (2013) J. Am. Chem. Soc., 135

Moser, C.C., Keske, J.M., Warncke, K., Farid, R.S., Dutton, P.L., (1992) Nature, 355, p. 796

Löwdin, P.O., (1963) Rev. Mod. Phys., 35, p. 724

Lewis, F.D., Wasielewski, M.R., (2013) Pure Appl. Chem., 85, p. 1379

Black, P.J., Bernhard, W.A., (2012) J. Phys. Chem. B, 116

Gust, D., Moore, T.A., Moore, A.L., (2001) Acc. Chem. Res., 34, p. 40

Pettersen, E.F., Goddard, T.D., Huang, C.C., Couch, G.S., Greenblatt, D.M., Meng, E.C., Ferrin, T.E., (2004) J. Comput. Chem., 25, p. 1605


Related activities ▼
No results.

Related papers ▼
UV-Induced Proton Transfer between DNA Strands (restricted access) (58 views)

Related bibliography ▼

Content: [X]
Extended

Authors: [X]
AND Paper type: [X]

AND Start date: End date: [X]   AND Site:    AND  IBB affiliation

[Clear form]

<=2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018   ALL YEARS

Sort by: date    title    journal    authors      impact factor

* Photoinduced Electron Transfer in DNA: Charge Shift Dynamics between 8-Oxo-Guanine Anion and Adenine (78 views)
Zhang Y, Dood J, Beckstead AA, Li X-B, Nguyen KV, Burrows CJ, Improta R, Kohler B
J Phys Chem B (ISSN: 1520-6106, 1520-5207, 1520-5207electronic), 2015; 119(24): 7491-7502.

View    Export to BibTeX    Export to EndNote    Upload PDF


1 Records (1 excluding Abstracts and Conferences).
Total impact factor: 3.187 (3.187 excluding Abstracts and Conferences).
Total 5-year impact factor: 3.265 (3.265 excluding Abstracts and Conferences).



Your bibliography query: (([btitle, keywords, abstract] EXCITED AND [btitle, keywords, abstract] STATES AND [btitle, keywords, abstract] FREE AND [btitle, keywords, abstract] RADICAL AND [btitle, keywords, abstract] REACTIONS AND [btitle, keywords, abstract] PROTON AND [btitle, keywords, abstract] TRANSFER AND [btitle, keywords, abstract] QUANTUM AND [btitle, keywords, abstract] THEORY)) AND NOT [id] = 52896



Last modified by Marco Comerci on Thursday 08 October 2015, 10:34:44
71 views. Last viewed on Sunday 19 November 2017, 20:59:26


Webmaster and developer: Marco Comerci
For problems and suggestions: adminibb.cnr.it
Last updated: Friday 24 November 2017, 7:20:14