Reversal of Warburg Effect and Reactivation of Oxidative Phosphorylation by Differential Inhibition of EGFR Signaling Pathways in Non-Small Cell Lung Cancer (490 visite)
Clin Cancer Res (ISSN: 1078-0432, 1078-0432linking, 1078-0432print), 2015 Nov 15; 21(22): 5110-5120.
Tipo di articolo: Journal Article, Research Support, Non-U. S. Gov'T,
Impact factor: 8.738, Impact factor a 5 anni: 8.751
Url: Non disponibile.
Parole chiave: Egfr, Aerobic Glycolysis, Oxidative Phosphorylation, Non-Small Cell Lung Cancer, Animals , Apoptosis Drug Effects , Carcinoma, Non-Small-Cell Lung Drug Therapy Genetics Metabolism Pathology , Cell Line, Tumor , Cell Proliferation Drug Effects , Glucose Metabolism , Humans , Lactic Acid Metabolism , Mice , Mitochondria Drug Effects Metabolism Pathology , Oxidative Phosphorylation Drug Effects , Protein Kinase Inhibitors Administration, Dosage , Proto-Oncogene Proteins C-Met Antagonists, Inhibitors Genetics , Receptor, Epidermal Growth Factor Antagonists, Signal Transduction Drug Effects , Xenograft Model Antitumor Assays,
Affiliazioni:
*** IBB - CNR ***
Institute of Biostructures and Bioimages, National Research Council, Naples, Italy.
Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
Institute of Genetics and Biophysics, National Research Council, Naples, Italy.
Riferimenti:
Non disponibile.
Clin Cancer Res (ISSN: 1078-0432, 1078-0432linking, 1078-0432print), 2015 Nov 15; 21(22): 5110-5120.
Tipo di articolo: Journal Article, Research Support, Non-U. S. Gov'T,
Impact factor: 8.738, Impact factor a 5 anni: 8.751
Url: Non disponibile.
Parole chiave: Egfr, Aerobic Glycolysis, Oxidative Phosphorylation, Non-Small Cell Lung Cancer, Animals , Apoptosis Drug Effects , Carcinoma, Non-Small-Cell Lung Drug Therapy Genetics Metabolism Pathology , Cell Line, Tumor , Cell Proliferation Drug Effects , Glucose Metabolism , Humans , Lactic Acid Metabolism , Mice , Mitochondria Drug Effects Metabolism Pathology , Oxidative Phosphorylation Drug Effects , Protein Kinase Inhibitors Administration, Dosage , Proto-Oncogene Proteins C-Met Antagonists, Inhibitors Genetics , Receptor, Epidermal Growth Factor Antagonists, Signal Transduction Drug Effects , Xenograft Model Antitumor Assays,
Affiliazioni:
*** IBB - CNR ***
Institute of Biostructures and Bioimages, National Research Council, Naples, Italy.
Department of Advanced Biomedical Sciences, University of Naples Federico II, Naples, Italy.
Institute of Genetics and Biophysics, National Research Council, Naples, Italy.
Riferimenti:
Non disponibile.
PURPOSE: One of the hallmarks of cancer cells is the excessive conversion of glucose to lactate under normoxic conditions, also known as the Warburg effect. Here, we tested whether the targeted inhibition of EGFR may revert this effect and reactivate mitochondrial oxidative phosphorylation in non-small cell lung cancer (NSCLC). EXPERIMENTAL DESIGN: Sensitive (HCC827) and resistant (H1975 and H1993) NSCLC cells were treated with a panel of EGFR or MET inhibitors, and then tested for changes of EGFR signaling, glycolytic cascade, and mitochondrial function. Silencing of key glycolytic enzymes was then performed with targeted siRNAs. Furthermore, tumor-bearing nude mice treated with EGFR inhibitors were evaluated with (18)F-FDG PET/CT and tumors were analyzed for glycolytic and mitochondrial proteins. RESULTS: Effective inhibition of EGFR signaling in NSCLC cells induced a dramatic reduction of hexokinase II (HKII) and phospho-pyruvate kinase M2 (p-PKM2, Tyr105) levels as well as an upregulation of mitochondrial complexes subunits (OXPHOS). Accordingly, a decreased lactate secretion and increased intracellular ATP levels were also observed in response to EGFR inhibitors. Downregulation of HKII and PKM2 by targeted siRNA transfection did not cause upregulation of OXPHOS but enhanced the effects of EGFR TKIs. Conversely, selective inhibition of AKT and ERK1/2 caused OXPHOS upregulation and glycolysis inhibition, respectively. Similar findings were obtained in tumors from animals treated with appropriate EGFR inhibitors. CONCLUSIONS: Our findings indicate that EGFR inhibitors may reactivate oxidative phosphorylation of cancer cells and provide a mechanistic clue for the rational combination of agents targeting EGFR-dependent proliferation and glucose metabolism in cancer therapy. Clin Cancer Res; 21(22); 5110-20. (c)2015 AACR.
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Neve Polimeno M, Ierano C, D'Alterio C, Simona Losito N, Napolitano M, Portella L, Scognamiglio G, Tatangelo F, Maria Trotta A, Curley S, Costantini S, Liuzzi R, Izzo F, Scala S
* CXCR4 expression affects overall survival of HCC patients whereas CXCR7 expression does not (338 visite)
Cell Mol Immunol (ISSN: 1672-7681), 2014 Nov 3; 12(4): 474-482.
Impact Factor: 4.112
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Altieri F, Di Stadio CS, Severino V, Sandomenico A, Minopoli G, Miselli G, Di Maro A, Ruvo M, Chambery A, Quagliariello V, Masullo M, Rippa E, Arcari P
* Anti-amyloidogenic property of human gastrokine (364 visite)
Biochimie (ISSN: 0300-9084, 1638-6183, 0300-9084linking), 2014 Nov; 106C: 91-100.
Impact Factor: 2.963
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Formicola F, Riccardi A, Vigliar E, Biondi B, Accurso A, Del Vecchio W, Imbriaco M
* Multimetastatic medullary thyroid carcinoma to the breast: PET/CT--mammographic-US and MR findings (167 visite)
Breast J (ISSN: 1075-122x), 2014 Nov; 20(6): 653-654.
Impact Factor: 1.411
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De Rosa V, Iommelli F, Monti M, Fonti R, Del Vecchio S
* Early reduction of 18F-FDG uptake in non-small lung cancer treated with EGFR tyrosine kinase inhibitors reflects reversal of Warburg effect and reactivation of oxidative phosphorylation (173 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 1619-7070print), 2014 Oct; 41: N/D-N/D.
Impact Factor: 5.383
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Iommelli F, De Rosa V, Gargiulo S, Panico M, Monti M, Gramanzini M, Fonti R, Del Vecchio S
* Monitoring Reversal of Concurrent Mechanisms of Resistance to EGFR TKIs in Non-Small Cell Lung Cancer by 18F-FLT PET/CT (216 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 1619-7070print), 2014 Oct; 41: N/D-N/D.
Impact Factor: 5.383
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Capasso D, De Paola I, Liguoro A, Del Gatto A, Di Gaetano S, Guarnieri D, Saviano M, Zaccaro L
* Rgdechi-Hcit: Alpha V Beta 3 Selective Pro-Apoptotic Peptide As Potential Carrier For Drug Delivery Into Melanoma Metastatic Cells (269 visite)
Plosone (ISSN: 1932-6203, 1932-6203electronic), 2014 Sep 23; 9(9): e106441-e106441.
Impact Factor: 3.234
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Iommelli F, De Rosa V, Gargiulo S, Panico M, Monti M, Greco A, Gramanzini M, Ortosecco G, Fonti R, Brunetti A, Del Vecchio S
* Monitoring Reversal of MET-Mediated Resistance to EGFR Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer Using 3 '-Deoxy-3 '-[F-18]-Fluorothymidine Positron Emission Tomography (352 visite)
Clin Cancer Res (ISSN: 1078-0432, 1078-0432linking, 1078-0432print), 2014 Sep 15; 20(18): 4806-4815.
Impact Factor: 8.722
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Orditura M, Galizia G, Di Martino N, Ancona E, Castoro C, Pacelli R, Morgillo F, Rossetti S, Gambardella V, Farella A, Laterza MM, Ruol A, Fabozzi A, Napolitano V, Iovino F, Lieto E, Fei L, Conzo G, Ciardiello F, De Vita F
* Effect of preoperative chemoradiotherapy on outcome of patients with locally advanced esophagogastric junction adenocarcinoma-a pilot study (1730 visite)
Curr Oncol (ISSN: 1198-0052), 2014 Jun; 21(3): 125-133.
Impact Factor: 1.785
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Pedicini P, Strigari L, Benassi M, Caivano R, Fiorentino A, Nappi A, Salvatore M, Storto G
* Critical dose and toxicity index of organs at risk in radiotherapy: analyzing the calculated effects of modified dose fractionation in non-small cell lung cancer (293 visite)
Med Dosim (ISSN: 0958-3947, 1873-4022), 2014 Mar; 39(1): 23-30.
Impact Factor: 0.76
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Federico A, Zappavigna S, Romano M, Grieco P, Luce A, Marra M, Gravina AG, Stiuso P, D'Armiento FP, Vitale G, Tuccillo C, Novellino E, Loguercio C, Caraglia M
* Urotensin-II receptor is over-expressed in colon cancer cell lines and in colon carcinoma in humans (283 visite)
Eur J Clin Invest (ISSN: 0014-2972, 1365-2362), 2014 Mar; 44(3): 285-294.
Impact Factor: 2.734
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Iommelli F, De Rosa V, Fonti R, Del Vecchio S
* Molecular Imaging For Detection Of Sensitivity And Resistance To Egfr Tyrosine Kinase Inhibitors In Non-Small Cell Lung Cancer (185 visite)
Clin Transl Imaging (ISSN: 2281-5872print, 2281-7565online), 2014 Feb 20; 2(1): 43-53.
Impact Factor: 0
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D'Arco F, Pizzuti LM, Romano F, Natella V, Laccetti E, Storto G, Maurea S, Mainenti PP
* MRI findings of a remote and isolated vaginal metastasis revealing an adenocarcinoma of the mid-sigmoid colon (202 visite)
Pol J Radiol (ISSN: 1733-134x, 0137-7183, 1733-134xlinking), 2014 Feb 18; 79: 33-35.
Impact Factor: 0.567
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Dell'Aprovitola N, Guarino S, Del Vecchio W, Camera L, Chiancone F, Imbimbo C, Salvatore M, Imbriaco M
* Xanthogranulomatous pyelonephritis mimicking a renal cell carcinoma: a unique and challenging case (225 visite)
Acta Radiologica Short Reports (ISSN: 2047-9816), 2014 Jan; 3(1): 2047981613513763-2047981613513763.
Impact Factor: 1.35
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Perri F, Dell'Oca I, Muto P, Schiavone C, Aversa C, Fulciniti F, Solla R, Scarpati GD, Buonerba C, Di Lorenzo G, Caponigro F
* Optimal management of a patient with recurrent nasopharyngeal carcinoma (198 visite)
World Journal Of Clinical Cases (ISSN: 2307-8960), 2014; 2(7): 297-300.
Impact Factor: 0.895
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Ciarmiello A, Gaeta MC, Meniconi M, Milano A, Alfano B, Del Vecchio S, Salvatore M
* Parametric MR dynamic imaging for breast lesions characterization and prediction of lymph nodes involvement (241 visite)
Curr Radiopharm (ISSN: 1874-4710, 1874-4729), 2014; 7(2): 91-99.
Impact Factor: 0.643
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Sorriento D, Pascale AV, Finelli R, Carillo AL, Annunziata R, Trimarco B, Iaccarino G
* Targeting mitochondria as therapeutic strategy for metabolic disorders (358 visite)
Sci World J The Scientific World Journal (ISSN: 1537-744x), 2014; 2014: N/D-N/D.
Impact Factor: 1.219
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Dynkevich Y, Rother KI, Whitford I, Qureshi S, Galiveeti S, Szulc AL, Danoff A, Breen TL, Kaviani N, Shanik MH, LeRoith D, Vigneri R, Koch CA, Roth J
* Tumors, IGF-2, and Hypoglycemia: Insights From the Clinic, the Laboratory, and the Historical Archive (917 visite)
Endocrine Reviews (ISSN: 0163-769x), 2013 Dec; 34(6): 798-826.
Impact Factor: 19.358
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Montefusco S, Esposito R, D'Andrea L, Monti MC, Dunne C, Dolan B, Tosco A, Marzullo L, Clyne M
* Copper promotes TFF1-mediated Helicobacter pylori colonization (315 visite)
Plosone (ISSN: 1932-6203, 1932-6203electronic), 2013 Nov 13; 8(11): e79455-e79455.
Impact Factor: 3.534
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Pedicini P, Fiorentino A, Improta G, Nappi A, Salvatore M, Storto G
* Estimate of the accelerated proliferation by protein tyrosine phosphatase (PTEN) over expression in postoperative radiotherapy of head and neck squamous cell carcinoma (209 visite)
Clin Transl Oncol (ISSN: 1699-048x), 2013 Nov; 15(11): 919-924.
Impact Factor: 1.6
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Fonti R, Mainolfi C, Anzivino A, Camera L, Faggiano A, Colao A, Salvatore M, Del Vecchio S
* 18F-FDG-PET/CT and 111In-Octreotide SPECT in Patients with Metastatic Medullary Thyroid Carcinoma (178 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2013 Oct; 40: N/D-N/D.
Impact Factor: 5.217
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Iommelli F, De Rosa V, Gargiulo S, Panico M, Monti M, Ortosecco G, Greco A, Gramanzini M, Fonti R, Brunetti A, Del Vecchio S
* 18F-FLT PET/CT for Detection of Functional Cross-talk between MET and EGFR in Non-small Cell Lung Cancer Resistant to EGFR Inhibitors (254 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2013 Oct; 40: N/D-N/D.
Impact Factor: 5.217
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De Rosa V, Iommelli F, Votta G, Monti M, Ortosecco G, Fonti R, Mainolfi C, Stoppelli M, Del Vecchio S
* Changes of Glycolytic Pathway in Response to Efficient Inhibition of EGFR Signaling in Non-small Cell Lung Cancer (NSCLC) (186 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2013 Oct; 40: N/D-N/D.
Impact Factor: 5.217
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D'Antuono F, Gallicchio R, Venetucci A, Nardelli A, Giacomobono S, Pellegrino T, Tempone A, Di Leo A, Gattozzi D, Storto G
* Does remnant from differentiated thyroid microcarcinoma patients really not be treated with Iodine-131 ablation? (170 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2013 Oct; 40: N/D-N/D.
Impact Factor: 5.217
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Gallicchio R, Giacomobono S, Capacchione D, Nardelli A, Barbato F, Nappi A, Pellegrino T, Storto G
* Should patients with remnants from thyroid microcarcinoma really not be treated with iodine-131 ablation? (235 visite)
Endocrine (ISSN: 1355-008x, 1355-008xlinking), 2013 Oct; 44(2): 426-433.
Impact Factor: 3.527
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Passaro C, Abagnale A, Libertini S, Volpe M, Botta G, Cella L, Pacelli R, Halldèn G, Gillespie D, Portella G
* Ionizing radiation enhances dl922-947-mediated cell death of anaplastic thyroid carcinoma cells (290 visite)
Endocr Relat Cancerendocrine Related Cancer (ISSN: 1351-0088), 2013 Sep 19; 20(5): 633-647.
Impact Factor: 4.907
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D'Angelo D, Borbone E, Palmieri D, Uboldi S, Esposito F, Frapolli R, Pacelli R, D'Incalci M, Fusco A
* The impairment of the High Mobility Group A (HMGA) protein function contributes to the anticancer activity of trabectedin (267 visite)
European Journal Of Cancer (ISSN: 0959-8049), 2013 Mar; 49(5): 1142-1151.
Impact Factor: 4.819
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Buanne P, Renzone G, Monteleone F, Vitale M, Monti SM, Sandomenico A, Garbi C, Montanaro D, Accardo M, Troncone G, Zatovicova M, Csaderova L, Supuran CT, Pastorekova S, Scaloni A, De Simone G, Zambrano N
* Characterization of carbonic anhydrase ix interactome reveals proteins assisting its nuclear localization in hypoxic cells (261 visite)
J Proteome Res (ISSN: 1535-3893), 2013 Jan; 12(1): 282-292.
Impact Factor: 5.001
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Zannetti A, Iommelli F, De Rosa V, Nardelli A, Ortosecco G, Del Vecchio S
* Combined Imaging with 18F-FLT PET/CT and 99m-Tc-Hynic-Annexin V SPECT for Personalized Therapy with EGFR Antagonists and Bcl-xL Inhibitors in Non-Small Cell Lung Cancer (266 visite)
European Journal Of Cancer (ISSN: 0959-8049), 2012 Nov; 48: N/D-N/D.
Impact Factor: 5.061
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Campanile F, Maurea S, Mainenti PP, Corvino A, Imbriaco M
* Duodenal Involvement by Breast Cancer (159 visite)
Breast Journal (ISSN: 1075-122x), 2012 Nov; 18(6): 615-616.
Impact Factor: 1.831
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Fusari M, Sorrentino N, Bottazzi EC, Del Vecchio W, Cozzolino I, Maurea S, Salvatore M, Imbriaco M
* Primary signet ring cell carcinoma of the appendix mimicking acute appendicitis (153 visite)
Acta Radiologica Short Reports (ISSN: 2047-9816), 2012 Oct 5; 1(9): 2012-2012.
Impact Factor: 1.35
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Zannetti A, Iommelli F, De Rosa V, Salvatore M, Del Vecchio S
* Small animal SPECT with 99m-Tc-Hynic-annexin V for detection of non-small cell lung cancer resistance to EGFR antagonists and its reversal by Bcl-xL inhibitors (281 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2012 Oct; 39: N/D-N/D.
Impact Factor: 5.114
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Pedicini P, Nappi A, Strigari L, Jereczek-Fossa BA, Alterio D, Cremonesi M, Botta F, Vischioni B, Caivano R, Fiorentino A, Improta G, Storto G, Benassi M, Orecchia R, Salvatore M
* Correlation between EGFr expression and accelerated proliferation during radiotherapy of head and neck squamous cell carcinoma (226 visite)
Radiation Oncology (ISSN: 1748-717x), 2012 Sep 24; 7: 143-143.
Impact Factor: 2.107
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Zannetti A, Iommelli F, Speranza A, Salvatore M, Del Vecchio S
* 3'-deoxy-3'-18F-fluorothymidine (FLT) PET/CT to guide therapy with epidermal growth factor receptor (EGFR) antagonists and Bcl-xL inhibitors in non-small cell lung cancer (447 visite)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 2012 Mar 1; 53(3): 443-450.
Impact Factor: 5.774
Dettagli Esporta in BibTeX Esporta in EndNote
Zannetti A, Iommelli F, Speranza A, Salvatore M, Del Vecchio S
* 3'-deoxy-3'-18F-fluorothymidine PET/CT to guide therapy with epidermal growth factor receptor antagonists and Bcl-xL inhibitors in non-small cell lung cancer (337 visite)
J Nucl Med (ISSN: 1535-5667, 0161-5505, 1535-5667electronic), 2012 Mar 1; 53(3): 443-450.
Impact Factor: 5.774
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Vassallo M, Giuseppe M, Quarantelli M, Pastore G, Paladini D
* Choroid plexus carcinoma: Prenatal characterization by 3-dimensional sonography and magnetic resonance imaging perinatal management, and natural history (227 visite)
J Ultrasound Med (ISSN: 0278-4297, 1550-9613), 2012 Feb; 31(2): 337-340.
Impact Factor: 1.402
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Orditura M, Galizia G, Morgillo F, Martinelli E, Lieto E, Vitiello F, Di Martino N, Pacelli R, Renda A, Ciardiello F, De Vita F
* Complete Response To Preoperative Chemoradiation And Survival In Esophageal Cancer: A Pooled Analysis Of Three Single-Institution Phase Ii Trials (310 visite)
Diseases Of The Esophagus, 2012 Feb; 142(5): 130-136.
Impact Factor: 2.057
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De Rosa V, Erkekoǧlu P, Forestier A, Favier A, Hincal F, Diamond AM, Douki T, Rachidi W
* Low doses of selenium specifically stimulate the repair of oxidative DNA damage in LNCaP prostate cancer cells (259 visite)
Free Radic Res Free Radical Research (ISSN: 1071-5762), 2012; 46(2): 105-115.
Impact Factor: 3.279
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Zeppa P, Barra E, Napolitano V, Cozzolino I, Troncone G, Picardi M, De Renzo A, Mainenti PP, Vetrani A, Palombini L
* Impact of Endoscopic Ultrasound-Guided Fine Needle Aspiration (EUS-FNA) in Lymph Nodal and Mediastinal Lesions: A Multicenter Experience (344 visite)
Diagnostic Cytopathology (ISSN: 8755-1039), 2011 Oct; 39(10): 723-729.
Impact Factor: 1.16
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Ocak M, Helbok A, Rangger C, Peitl PK, Nock BA, Morelli G, Eek A, Sosabowskijk, Breeman WA, Reubi JC, Decristoforo C
* Comparison of biological stability and metabolism of CCK2 receptor targeting peptides, a collaborative project under COST BM0607 (417 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2011 Sep; 38(8): 1426-1435.
Impact Factor: 4.991
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Ruvo M, Sandomenico A, Tudisco L, De Falco S
* Branched peptides for the modulation of protein-protein interactions: More arms are better than one? (374 visite)
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2011 Jun; 18(16): 2429-2437.
Impact Factor: 4.859
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Cuocolo A
Current research in nuclear medicine and molecular imaging in Italy: Highlights of the 10th National Congress of the Italian Association of Nuclear Medicine and Molecular Imaging (299 visite)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2011 Jun; 55(3): 280-300.
Impact Factor: 1.724
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Maurea S, Corvino A, Imbriaco M, Avitabile G, Mainenti P, Camera L, Galizia G, Salvatore M
* Simultaneous non-functioning neuroendocrine carcinoma of the pancreas and extra-hepatic cholangiocarcinoma. A case of early diagnosis and favorable post-surgical outcome (190 visite)
Jop (ISSN: 1590-8577, 1590-0857), 2011 May 6; 12(3): 255-258.
Impact Factor: 0
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Falciani C, Accardo A, Brunetti J, Tesauro D, Lelli B, Pini A, Bracci L, Morelli G
* Target-Selective Drug Delivery through Liposomes Labeled with Oligobranched Neurotensin Peptides (327 visite)
Chemmedchem (ISSN: 1860-7179, 1860-7187, 1860-7187electronic), 2011 Apr 4; 6(4): 678-685.
Impact Factor: 3.151
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Mainenti PP, Iodice D, Segreto S, Storto G, Magliulo M, De Palma GD, Salvatore M, Pace L
* Colorectal cancer and 18FDG-PET/CT: what about adding the T to the N parameter in loco-regional staging? (189 visite)
World J Gastroentero (ISSN: 2219-2840, 1007-9327, 1007-9327linking), 2011 Mar 21; 17(11): 1427-1433.
Impact Factor: 2.471
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Mainenti PP, Mancini M, Mainolfi C, Camera L, Maurea S, Manchia A, Tanga M, Persico F, Addeo P, D'Antonio D, Speranza A, Bucci L, Persico G, Pace L, Salvatore M
* Detection of colo-rectal liver metastases: Prospective comparison of contrast enhanced US, multidetector CT, PET/CT, and 1. 5 Tesla MR with extracellular and reticulo-endothelial cell specific contrast agents (235 visite)
Abdom Imaging (ISSN: 0942-8925, 1432-0509), 2010 Oct; 35(5): 511-521.
Impact Factor: 1.95
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Orditura M, Galizia G, Napolitano V, Martinelli E, Pacelli R, Lieto E, Aurilio G, Vecchione L, Morgillo F, Catalano G, Ciardiello F, Del Genio A, Di Martino N, De Vita F
* Weekly Chemotherapy with Cisplatin and Paclitaxel and Concurrent Radiation Therapy as Preoperative Treatment in Locally Advanced Esophageal Cancer: A Phase II Study (201 visite)
Cancer Investigation (ISSN: 0735-7907), 2010 Oct; 28(8): 820-827.
Impact Factor: 2.39
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Di Lorenzo G, Imbimbo M, Leopardo D, Marciano R, Federico P, Buonerba C, Salvatore B, Marinelli A, Palmieri G. A
* A long-lasting response to sorafenib treatment in an advanced hepatocellular carcinoma patient (174 visite)
Int J Immunopathol Pharmacol (ISSN: 0394-6320), 2010 Jul; 23(3): 951-954.
Impact Factor: 2.685
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Bombardieri E, Ambrosini V, Aktolun C, Baum RP, Bishof-delaloye A, Del Vecchio S, Maffioli L, Mortelmans L, Oyen W, Pepe G, Chiti A
* In-111-pentetreotide scintigraphy: procedure guidelines for tumour imaging (313 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2010 Jul; 37(7): 1441-1448.
Impact Factor: 5.036
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Del Vecchio S, Zannetti A, Fonti R, Iommelli F, Pizzuti LM, Lettieri A, Salvatore M
* PET/CT in cancer research: From preclinical to clinical applications (443 visite)
Contrast Media Mol Imaging (ISSN: 1555-4309, 1555-4309linking), 2010 Jul; 5(4): 190-200.
Impact Factor: 4.02
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Del Vecchio S, Zannetti A, Iommelli F, Lettieri A, Brunetti A, Salvatore M
* Molecular imaging of tumor microenvironment (314 visite)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2010 Jun; 54(3): 243-258.
Impact Factor: 1.724
Dettagli Esporta in BibTeX Esporta in EndNote
Del Vecchio S, Zannetti A, Iommelli F, Lettieri A, Brunetti A, Salvatore M
* Molecular imaging of tumor microenvironment: Challenges and perspectives (426 visite)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2010 Jun; 54(3): 249-258.
Impact Factor: 1.724
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Fusari M, Maurea S, Imbriaco M, Mollica C, Avitabile G, Soscia F, Camera L, Salvatore M
* Comparison between multislice CT and MR imaging in the diagnostic evaluation of patients with pancreatic masses (195 visite)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 2010 Apr; 115(3): 453-466.
Impact Factor: 1.618
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Caprio MG, Cangiano A, Imbriaco M, Soscia F, Di Martino G, Farina A, Avitabile G, Pace L, Forestieri P, Salvatore M
* Dual-time-point [18F]-FDG PET/CT in the diagnostic evaluation of suspicious breast lesions (276 visite)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 2010 Mar; 115(2): 215-224.
Impact Factor: 1.618
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Alberobello AT, D'Esposito V, Marasco D, Doti N, Ruvo M, Bianco R, Tortora G, Esposito I, Fiory F, Miele C, Beguinot F, Formisano P
* Selective Disruption of Insulin-like Growth Factor-1 (IGF-1) Signaling via Phosphoinositide-dependent Kinase-1 Prevents the Protective Effect of IGF-1 on Human Cancer Cell Death (295 visite)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2010 Feb 26; 285(9): 6563-6572.
Impact Factor: 5.328
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Capaccio D, Ciccodicola A, Sabatino L, Casamassimi A, Pancione M, Fucci A, Febbraro, Merlino A, Graziano G, Colantuoni V
* A novel germline mutation in Peroxisome Proliferator-Activated Receptor γ gene associated with large intestine polyp formation and dyslipidemia (209 visite)
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2010; 1802(6): 572-581.
Impact Factor: 2.773
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Caleo O, Maurea S, Klain M, Salvatore B, Storto G, Mancini M, Pace L, Salvatore M
* Postsurgical diagnostic evaluation of patients with differentiated thyroid carcinoma: Comparison of ultrasound, iodine-131 scintigraphy and PET with fluorine-18 fluorodeoxyglucose (180 visite)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 2009 Dec; 114(8): 1385-1385.
Impact Factor: 1.454
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Ierano C, Giuliano P, D'Alterio C, Cioffi M, Mettivier V, Portella L, Napolitano M, Barbieri A, Arra C, Liguori G, Franco R, Palmieri G, Rozzo C, Pacelli R, Castello G, Scala S
* A point mutation (G574A) in the chemokine receptor CXCR4 detected in human cancer cells enhances migration (280 visite)
Cell Cycle (ISSN: 1538-4101), 2009 Apr 15; 8(8): 1228-1237.
Impact Factor: 4.087
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Maurea S, Caleo O, Mollica C, Imbriaco M, Mainenti PP, Palumbo C, Mancini M, Camera L, Salvatore M
* Comparative diagnostic evaluation with MR cholangiopancreatography, ultrasonography and CT in patients with pancreatobiliary disease (236 visite)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 2009 Apr; 114(3): 390-402.
Impact Factor: 1.454
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Storto G, Nicolai E, Salvatore M
* [18F]FDG-PET-CT for early monitoring of tumor response: When and why (272 visite)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2009 Apr; 53(2): 167-180.
Impact Factor: 1.724
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Zaccaro L, Del Gatto A, Pedone C, Saviano M
* Peptides for tumour therapy and diagnosis: current status and future directions (393 visite)
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2009 Mar; 16(7): 780-795.
Impact Factor: 4.708
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Maurea S, Soricelli A, Salvatore M
* Characterization of hypersecreting or non-hypersecreting adrenal adenomas: Comparison between iodine-131 nor-cholesterol scintigraphy and magnetic resonance imaging (184 visite) (PDF 190 visite)
Curr Radiopharm (ISSN: 1874-4710, 1874-4729), 2009; 2(1): 56-62.
Impact Factor: 0.643
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Imbriaco M, Caprio MG, Limite G, Pace L, De Falco T, Capuano E, Salvatore M
* Dual-time-point 18F-FDG PET/CT versus dynamic breast MRI of suspicious breast lesions (172 visite)
Ajr Am J Roentgenol (ISSN: 1546-3141, 0361-803x, 1546-3141electronic), 2008 Nov; 191(5): 1323-1330.
Impact Factor: 2.94
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Zannetti A, Iommelli F, Fonti R, Papaccioli A, Sommella J, Lettieri A, Pirozzi G, Bianco R, Tortora G, Salvatore M, Del Vecchio S
* Gefitinib induction of in vivo detectable signals by Bcl-2/Bcl-xL modulation of inositol trisphosphate receptor type (346 visite)
Clin Cancer Res (ISSN: 1078-0432, 1078-0432linking, 1078-0432print), 2008 Aug 15; 14(16): 5209-5219.
Impact Factor: 6.488
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Sinibaldi F, Fiorucci L, Patriarca A, Lauceri R, Ferri T, Coletta M, Santucci R
* Insights into cytochrome c-cardiolipin interaction. Role played by ionic strength (228 visite)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2008 Jul 1; 47(26): 6928-6935.
Impact Factor: 3.379
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Salvatore B, Paone G, Klain M, Storto G, Nicolai E, D'Amico D, Della Morte AM, Pace L, Salvatore M
* Fluorodeoxyglucose PET/CT in patients with differentiated thyroid cancer and elevated thyroglobulin after total thyroidectomy and 131I ablation (227 visite)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2008 Mar; 52(1): 2-8.
Impact Factor: 1.724
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Caleo O, Maurea S, Klain M, Salvatore B, Storto G, Mancini M, Pace L, Salvatore M
* Postsurgical diagnostic evaluation of patients with differentiated thyroid carcinoma: Comparison of ultrasound, iodine-131 scintigraphy and PET with fluorine-18 fluorodeoxyglucose (193 visite)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 2008 Mar; 113(2): 278-288.
Impact Factor: 0.955
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Atlante A, Amadoro G, Bobba A, de Bari L, Corsetti V, Pappalardo G, Marra E, Calissano P, Passarella S
* A peptide containing residues 26-44 of tau protein impairs mitochondrial oxidative phosphorylation acting at the level of the adenine nucleotide translocator (248 visite)
Bba-Gen Subjects (ISSN: 0005-2728, 0006-3002print, 0006-3002linking), 2008; 1777(10): 1289-1300.
Impact Factor: 4.447
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Mainenti PP, Mainolfi C, Storto G, Salvatore B, Nardelli A, De Marino M, Caliendo A, Nappi R, Pace L, Salvatore M
* Detection of liver Metastases in patients with colorectal carcinoma: Comparison of multidetector-CT, Mr, ultrasound and PET-CT (190 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2007 Oct; 34: N/D-N/D.
Impact Factor: 4.101
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Mainenti PP, Salvatore B, Sirignano C, De Falco T, Speranza A, Fiumara G, Ricci F, Evangelista L, Pace L, Salvatore M
* PET/CT colonography in patients with colo-rectal polyps: A feasibility study (192 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2007 Oct; 34(10): 1594-1603.
Impact Factor: 4.101
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Aloj L, Aurilio M, Rinaldi V, D'Ambrosio L, Tesauro D, Peitl PK, Maina T, Mansi R, Von Guggenberg E, Joosten L, Sosabowski JK, Breeman WA, De Blois E, Koelewijn S, Melis M, Waser B, Beetschen K, Reubi JC, De Jong M
* The EEE project (327 visite)
Proc Int Cosm Ray Conf Icrc Universidad Nacional Autonoma De Mexico, 2007; 5(HEPART2): 977-980.
Impact Factor: 0
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Leese MP, Leblond B, Smith A, Newman SP, Di Fiore A, De Simone G, Supuran CT, Purohit A, Reed MJ, Potter BVL
* 2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro SAR, protein crystallography, and in vivo activity (637 visite)
J Med Chem (ISSN: 0022-2623print, 0022-2623linking, 1520-4804), 2006 Dec 28; 49(26): 7683-7696.
Impact Factor: 5.115
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Mainenti PP, Cirillo LC, Camera L, Persico F, Cantalupo T, Pace L, De Palma GD, Persico G, Salvatore M
* Accuracy of single phase contrast enhanced multidetector CT colonography in the preoperative staging of colo-rectal cancer (205 visite)
Eur J Radiol (ISSN: 0720-048x), 2006 Dec; 60(3): 453-459.
Impact Factor: 1.332
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Maurea S, Imbriaco M, D'Angelillo M, Mollica C, Camera L, Salvatore M
* Diagnostic accuracy of chemical-shift MR imaging to differentiate between adrenal adenomas and non adenoma adrenal lesions (238 visite)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 2006 Sep; 111(5): 674-686.
Impact Factor: 1.368
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Tauchmanovà L, Pivonello R, Di Somma C, Rossi R, De Martino MC, Camera L, Klain M, Salvatore M, Lombardi G, Colao A
* Bone demineralization and vertebral fractures in endogenous cortisol excess: Role of disease etiology and gonadal status (231 visite)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2006 May; 91(5): 1779-1784.
Impact Factor: 5.799
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Iommelli F, Zannetti A, Pepe S, Sabbatino F, Laus G, Ghidelli L, Solla R, Scala S, Del Vecchio S, Salvatore M, Pacelli R
* Inhibition of NF-kappa B activity potentiates ionizing radiation and cisplatin induced cell killing of anaplastic thyroid carcinoma cells (303 visite)
Meetingproceedings Of The American Association For Cancer Research Annual (ISSN: 0197-016x), 2006 Apr; 47: N/D-N/D.
Impact Factor: 0
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Morante A, Romano M, Cuomo A, De Sio I, Cozzolino A, Mucherino C, Salerno R, Blanco C, Romano M
* Massive gastric ulceration after transarterial chemoembolization for hepatocellular carcinoma (126 visite)
Gastrointestinal Endoscopy (ISSN: 0016-5107), 2006 Apr; 63(4): 718-720.
Impact Factor: 4.825
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Imbriaco M, Smeraldo D, Liuzzi R, Carrillo F, Cacace G, Vecchione D, Diglio A, Salvatore M
* Multislice CT with single-phase technique in patients with suspected pancreatic cancer (173 visite)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 2006 Mar; 111(2): 159-166.
Impact Factor: 1.368
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Pace L, Klain M, Albanese C, Salvatore B, Storto G, Soricelli A, Salvatore M
* Short-term outcome of differentiated thyroid cancer patients receiving a second iodine-131 therapy on the basis of a detectable serum thyroglobulin level after initial treatment (260 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2006 Feb; 33(2): 179-183.
Impact Factor: 4.041
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Sirignano C, Soscia E, Mainenti PP, Camera L, Salvatore M
* Tumor Thrombus In The Right Atrium And In The Inferior Vena Cava As Primary Clinical Manifestations Of Hepatocellular Carcinoma. A Case Report (202 visite)
42 Congresso Nazionale Sirm Milano, 2006; N/D: 1-3.
Impact Factor: 0
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Sirignano C, Smeraldo D, Soscia E, Salvatore M
* Carcinoma Arising In A Zenker’s Diverticulum: A Case Report (134 visite)
1st World Congress Of Thoracic Imaging Firenze Italy, 2005 Oct; N/D: N/D-N/D.
Impact Factor: 0
Dettagli Esporta in BibTeX Esporta in EndNote
Pace L, Klain M, Soricelli A, Albanese C, Salvatore B, Storto G, Salvatore M
* Short Term Outcome of Differentiated Thyroid Cancer Patients with Detectable Serum Thyroglobulin after Initial Treatment Receiving a Second 131-IODINE Therapy (190 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2005 Sep; 32: 179-183.
Impact Factor: 3.883
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Cozzolino R, Palladino P, Rossi F, Cali G, Benedetti E, Laccetti P
* Antineoplastic cyclic astin analogues kill tumour cells via caspase-mediated induction of apoptosis (293 visite)
Carcinogenesis (ISSN: 0143-3334), 2005 Apr; 26(4): 733-739.
Impact Factor: 5.108
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Tauchmanovà L, Pensabene M, Capuano I, Spagnoletti I, Zeppa P, Del Vecchio S, Mainenti PP, De Rosa G, Colao A, Contegiacomo A
* Poorly differentiated small cell neuroendocrine carcinoma localized in three different endocrine glands: Response to chemotherapy and octreotide LAR (248 visite)
J Endocrinol Invest (ISSN: 0391-4097, 1720-8386electronic), 2005 Apr; 28(4): 371-378.
Impact Factor: 1.496
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Imbriaco M, Megibow AJ, Ragozzino A, Liuzzi R, Mainenti PP, Bortone S, Camera L, Salvatore M
* Value of the single-phase technique in MDCT assessment of pancreatic tumors (182 visite)
Am J Roentgenol (ISSN: 0361-803x), 2005 Apr; 184(4): 1111-1117.
Impact Factor: 2.209
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Mainenti PP, Romano M, Imbriaco M, Camera L, Pace L, D'Antonio D, Bucci L, Galloro G, Salvatore M
* Added value of CT colonography after a positive conventional colonoscopy: Impact on treatment strategy (265 visite)
Abdom Imaging (ISSN: 0942-8925, 1432-0509), 2005 Jan; 30(1): 42-47.
Impact Factor: 1.034
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Borgatti M, Boyd DD, Lampronti I, Bianchi N, Fabbri E, Saviano M, Romanelli A, Pedone C, Gambari R
* Decoy molecules based on PNA-DNA chimeras and targeting Sp1 transcription factors inhibit the activity of urokinase-type plasminogen activator receptor (uPAR) promoter (270 visite)
Oncology Research (ISSN: 0965-0407), 2005; 15(7-8): 373-383.
Impact Factor: 1.844
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Tauchmanovà L, Colao A, Marzano LA, Sparano L, Camera L, Rossi A, Palmieri G, Marzano E, Salvatore M, Pettinato G, Lombardi G, Rossi R
* Andrenocortical carcinomas: Twelve-year prospective experience (171 visite)
World J Surg (ISSN: 0364-2313), 2004 Sep; 28(9): 896-903.
Impact Factor: 1.952
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Aloj L, Caracò C, Panico M, Zannetti A, Del Vecchio S, Tesauro D, De Luca S, Arra C, Pedone C, Morelli G, Salvatore M
* In vitro and in vivo evaluation of In-111-DTPAGlu-G-CCK8 for cholecystokinin-B receptor imaging (416 visite)
J Nucl Med (ISSN: 1535-5667, 0161-5505, 1535-5667electronic), 2004 Mar; 45(3): 485-494.
Impact Factor: 5.362
Dettagli Esporta in BibTeX Esporta in EndNote
Aloj L, Panico M, Caraco C, Del Vecchio S, Arra C, Affuso A, Accardo A, Mansi R, Tesauro D, De Luca S, Pedone C, Visentin R, Mazzi U, Morelli G, Salvatore M
* In vitro and in vivo characterization of Indium-111 and Technetium-99m labeled CCK-8 derivatives for CCK-B receptor imaging (339 visite)
Cancer Biotherapy And Radiopharmaceuticals (ISSN: 1084-9785, 1084-4978), 2004 Feb; 19(1): 93-98.
Impact Factor: 1.091
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Cortesi R, Mischiati C, Borgatti M, Breda L, Romanelli A, Saviano M, Pedone C, Gambari R, Nastruzzi C
* Formulations for natural and peptide nucleic acids based on cationic polymeric submicron particles (265 visite)
The Aaps Journal (ISSN: 1522-1059, 1550-7416), 2004 Jan 20; 6(1): N/D-N/D.
Impact Factor: 1.938
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Maurea S, Caracò C, Klain M, Mainolfi C, Salvatore M
* Imaging characterization of non-hypersecreting adrenal masses. Comparison between MR and radionuclide techniques (239 visite) (PDF 190 visite)
Q J Nucl Med Mol Im (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2004; 48(3): 188-197.
Impact Factor: 1.724
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d'Alesio V, Pacelli R, Durante M, Canale Cama G, Cella L, Gialanella G, Grossi G, Pugliese M, Punzo G, Sardi I, Scampoli P, Solla R, Salvatore M
* Lymph nodes in the irradiated field influence the yield of radiation-induced chromosomal aberrations in lymphocytes from breast cancer patients (223 visite)
Int J Radiat Oncol (ISSN: 0360-3016, 1879-355x, 1879-355xelectronic), 2003 Nov 1; 57(3): 732-738.
Impact Factor: 4.285
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Portella G, Pacelli R, Libertini S, Cella L, Vecchio G, Salvatore M, Fusco A
* ONYX-015 Enhances Radiation-Induced Death of Human Anaplastic Thyroid Carcinoma Cells (284 visite)
J Clin Endocrinol Metab Journal Of Clinical Endocrinology And Metabolism (ISSN: 0021-972x), 2003 Oct 1; 88(10): 5027-5032.
Impact Factor: 5.873
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Daniele S, Imbriaco M, Riccardi A, Selva G, di Nuzzo L, Salvatore M, Sodano A
* Mammographic and sonographic features of tubular breast carcinoma (177 visite)
Tumori (ISSN: 0300-8916, 0300-8916print, 0300-8916linking), 2003 Jul; 89(4): 417-420.
Impact Factor: 0.348
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Spalletti-cernia D, Sorrentino R, Di Gaetano S, Arciello A, Garbi C, Piccoli R, D'Alessio G, Vecchio G, Laccetti P, Santoro M
* Antineoplastic ribonucleases selectively kill thyroid carcinoma cells via caspase-mediated induction of apoptosis (221 visite)
Journal Of Clinical Endocrinology & Metabolism (ISSN: 0021-972x), 2003 Jun; 88(6): 2900-2907.
Impact Factor: 5.873
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Del Vecchio S, Zannetti A, Aloj L, Caracò C, Ciarmiello A, Salvatore M
* Inhibition of early Tc-99m-MIBI uptake by Bcl-2 anti-apoptotic protein overexpression in untreated breast carcinoma (370 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2003 Jun; 30(6): 879-887.
Impact Factor: 3.324
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Romano M, Giojelli A, Tamburrini O, Salvatore M
* Chemoembolization for hepatocellular carcinoma: Effect of intraarterial lidocaine in peri- and post-procedural pain and hospitalization (264 visite)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 2003 Apr; 105(4): 350-355.
Impact Factor: 1.368
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Lomax AJ, Cella L, Weber D, Kurtz JM, Miralbell R
* Potential role of IMRT and protons in the treatment of the breast and regional nodes (229 visite)
Int J Rad Oncol Biol Phys, 2003 Mar 1; 48(3Supplement): 785-792.
Impact Factor: 0.155
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Biondi B, Palmieri EA, Pagano L, Klain M, Scherillo G, Salvatore M, Fenzi G, Lombardi G, Fazio S
* Cardiovascular safety of acute recombinant human thyrotropin administration to patients monitored for differentiated thyroid cancer (278 visite)
J Clin Endocrinol Metab (ISSN: 0021-972x), 2003 Jan; 88(1): 211-214.
Impact Factor: 5.873
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Lomax AJ, Cella L, Weber D, Kurtz JM, Miralbell R
* Potential role of intensity-modulated photons and protons in the treatment of the breast and regional nodes (218 visite)
Int J Radiat Oncol (ISSN: 0360-3016, 1879-355x, 1879-355xelectronic), 2003; 55(3): 785-792.
Impact Factor: 4.285
Dettagli Esporta in BibTeX Esporta in EndNote
Imbriaco M, Megibow AJ, Camera L, Pace L, Mainenti PP, Romano M, Selva G, Salvatore M
* Dual-phase versus single-phase helical CT to detect and assess resectability of pancreatic carcinoma (233 visite)
Am J Roentgenol (ISSN: 0361-803x), 2002 Jun; 178(6): 1473-1479.
Impact Factor: 2.424
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Del Vecchio S, Zannetti A, Ciarmiello A, Aloj L, Caracò C, Fonti R, Botti G, D'Aiuto G, Salvatore M
* Dynamic coupling of Tc-99m-MIBI efflux and apoptotic pathway activation in untreated breast cancer patients (312 visite)
Eur J Nucl Med (ISSN: 1619-7070, 0340-6997, 1619-7089), 2002 Jun; 29(6): 809-814.
Impact Factor: 3.568
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Aloj L, Panico M, Caracó C, Zannetti A, Del Vecchio S, Di Nuzzo C, Arra C, Morelli G, Tesauro D, De Luca S, Pedone C, Salvatore M
* Radiolabeling approaches for cholecystokinin B receptor imaging (379 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2002; 66(6): 370-380.
Impact Factor: 2.372
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De Falco S, Ruvoletto MG, Verdoliva A, Ruvo M, Raucci A, Marino M, Senatore S, Cassani G, Alberti A, Pontisso P, Fassina G
* Cloning and Expression of a Novel Hepatitis B Virus-binding Protein from HepG2 Cells (357 visite)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2001 Sep 28; 276(39): 36613-36623.
Impact Factor: 7.258
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Gridelli C, Manzione L, Perrone F, Veltri E, Cioffi R, Caprio MG, Frontini L, Rossi A, Barletta E, Barzelloni ML, Bilancia D, Gallo C
* Carboplatin plus paclitaxel in extensive small cell lung cancer: a multicentre phase 2 study (155 visite) (PDF 193 visite)
Br J Cancer (ISSN: 0007-0920print, 0007-0920linking), 2001 Jan 5; 84(1): 38-41.
Impact Factor: 3.942
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Imbriaco M, Del Vecchio S, Riccardi A, Pace L, Di Salle F, Di Gennaro F, Salvatore M, Sodano A
* Scintimammography with Tc-99m-MIBI versus dynamic MRI for non-invasive characterization of breast masses (273 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2001 Jan; 28(1): 56-63.
Impact Factor: 3.464
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Cirillo LC, Mainenti PP, Imbriaco M, Franco R, Gatta G, De Rosa G, Salvatore M
* Synchronous primary adenocarcinoma and adenosquamous carcinoma of the esophagus (159 visite)
Eur Radiol (ISSN: 0938-7994, 1432-1084electronic), 2001; 11(10): 1964-1967.
Impact Factor: 1.321
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Imbriaco M, Akhurst T, Hilton S, Yeung HW, Macapinlac HA, Mazumdar M, Pace L, Kemeny N, Erdi Y, Cohen A, Fong Y, Guillem J, Larson SM
Whole-Body FDG-PET in Patients with Recurrent Colorectal Carcinoma. A Comparative Study with CT (128 visite)
Clin Positron Imaging (ISSN: 1095-0397, 1095-0397linking), 2000 May; 3(3): 107-114.
Impact Factor: 0
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Zannetti A, Del Vecchio S, Carriero MV, Fonti R, Franco P, Botti G, D'Aiuto G, Stoppelli MP, Salvatore M
Coordinate up-regulation of Sp1 DNA-binding activity and urokinase receptor expression in breast carcinoma (326 visite)
Cancer Res (ISSN: 0008-5472, 1538-7445, 1538-7445electronic), 2000 Mar 15; 60(6): 1546-1551.
Impact Factor: 8.46
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Colasanti A, Kisslinger A, Liuzzi R, Quarto M, Riccio P, Roberti G, Tramontano D, Villani F
Hypericin photosensitization of tumor and metastatic cell lines of human prostate (173 visite)
J Photochem Photobiol B (ISSN: 1011-1344print, 1011-1344linking), 2000 Feb; 54(2-3): 103-107.
Impact Factor: 1.529
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Camera L, Imbriaco M, Marano I, Brunetti A, Selva G, Salvatore M
Dual-phase vs triphasic helical CT in the detection of hepato-cellular carcinoma in patients with liver cirrhosis (243 visite)
Radiology (ISSN: 0033-8419, 1527-1315, 1527-1315electronic), 1999 Nov; 213P: N/D-N/D.
Impact Factor: 4.621
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Maurea S, Mainolfi C, Bazzicalupo L, Panico MR, Imparato C, Alfano B, Ziviello M, Salvatore M
Imaging of adrenal tumors using FDG PET: comparison of benign and malignant lesions (216 visite) (PDF 190 visite)
Ajr Am J Roentgenol (ISSN: 0361-803x, 0361-803xlinking), 1999 Jul; 173(1): 25-29.
Impact Factor: 2.307
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Colao A, Lastoria S, Ferone D, Varrella P, Marzullo P, Pivonello R, Cerbone G, Acampa W, Salvatore M, Lombardi G
The pituitary uptake of In-111-DTPA-D-Phe(1)-octreotide in the normal pituitary and in pituitary adenomas (264 visite)
J Endocrinol Invest (ISSN: 0391-4097, 1720-8386electronic), 1999 Mar; 22(3): 176-183.
Impact Factor: 0.957
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Pasquali D, Bellastella A, Valente A, Botti G, Capasso I, del Vecchio S, Salvatore M, Colantuoni V, Sinisi AA
Retinoic acid receptors α, β and γ, and cellular retinol binding protein-I expression in breast fibrocystic disease and cancer (211 visite)
Eur J Endocrinol (ISSN: 0804-4643), 1997 Oct; 137(4): 410-414.
Impact Factor: 1.968
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Del Vecchio S, Ciarmiello A, Pace L, Potena MI, Carriero MV, Mainolfi C, Thomas R, D'Aiuto G, Tsuruo T, Salvatore M
Fractional retention of technetium-99m-sestamibi as an index of P- glycoprotein expression in untreated breast cancer patients (312 visite)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1997 Sep; 38(9): 1348-1351.
Impact Factor: 3.491
Dettagli Esporta in BibTeX Esporta in EndNote
Maurea S, Mainolfi C, Bazzicalupo L, Panico M, Imparato C, Alfano B, Ziviello M, Salvatore M
Characterization of adrenal tumors using F-18 FDG PET imaging: Comparison between benign and malignant lesions (340 visite) (PDF 190 visite)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1997 May; 38(5SUPPL.): 25-29.
Impact Factor: 3.491
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Ciarmiello A, Del Vecchio S, Carriero MV, Silvestro P, Botti G, Potena MI, D'Aiuto G, Salvatore M
Efflux rate of Tc-99m-Sestamibi as a predictor of the outcome of therapy in patients with advanced breast carcinoma (211 visite)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1997 May; 38(5SUPPL.): N/D-N/D.
Impact Factor: 3.491
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Vecchio SD, Ciarmiello A, Potena MI, Carriero MV, Mainolfi C, Botti G, Thomas R, Cerra M, D'Aiuto G, Tsuruo T, Salvatore M
In vivo detection of multidrug-resistant (MDR1) phenotype by technetium-99m sestamibi scan in untreated breast cancer patients (223 visite)
Eur J Nucl Med (ISSN: 0340-6997print, 0340-6997linking), 1997 Feb; 24(2): 150-159.
Impact Factor: 5.036
Dettagli Esporta in BibTeX Esporta in EndNote
Biondi B, Fazio S, Cuocolo A, Sabatini D, Nicolai E, Lombardi G, Salvatore M, Sacca L
Impaired cardiac reserve and exercise capacity in patients receiving long-term thyrotropin suppressive therapy with levothyroxine (200 visite)
J Clin Endocrinol Metab (ISSN: 0021-972x), 1996 Dec; 81(12): 4224-4228.
Impact Factor: 4.575
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Ciccotosto C, Storto ML, Merlino B, Sacco R, Buonsanto A, Bonomo L
Spiral Computerized Tomography And Videothoracoscopy In The Assessment Of Contralateral Nodular Lesions In Patients With Bronchogenic Carcinoma (185 visite)
Radiol Med, 1996 Jun; 91(6): 722-726.
Impact Factor: 0
Dettagli Esporta in BibTeX Esporta in EndNote
Li PY, Del Vecchio S, Fonti R, Carriero MV, Potena MI, Botti G, Miotti S, Lastoria S, Menard S, Colnaghi MI, Salvatore M
Local concentration of folate binding protein GP38 in sections of human ovarian carcinoma by in vitro quantitative autoradiography (318 visite)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1996 Apr; 37(4-6): 665-672.
Impact Factor: 3.491
Dettagli Esporta in BibTeX Esporta in EndNote
Ciarmiello A, Del Vecchio S, Potena MI, Carriero MV, Silvestro P, Botti G, D'Aiuto G, Tsuruo T, Salvatore M
99mTc-Sestamibi efflux and therapeutic response in patients with advanced breast carcinoma (170 visite)
Meetingproceedings Of The American Association For Cancer Research Annual (ISSN: 0197-016x), 1996; 37(0): N/D-N/D.
Impact Factor: 0
Dettagli Esporta in BibTeX Esporta in EndNote
Del Vecchio S, Ciarmiello A, Potena MI, Carriero MV, Thomas R, D'Aiuto G, Tsuruo T, Salvatore M
Detection of multidrug-resistant phenotype by 99mTc-Sestamibi scan in patients with breast carcinoma (165 visite)
Meetingproceedings Of The American Association For Cancer Research Annual (ISSN: 0197-016x), 1996; 37(0): N/D-N/D.
Impact Factor: 0
Dettagli Esporta in BibTeX Esporta in EndNote
Lastoria S, Maurea S, Vergara E, Acampa W, Varrella P, Klain M, Muto P, Bernardy JD, Salvatore M
Comparison of labeled MIBG and somatostatin analogs in imaging neuroendocrine tumors (244 visite)
Q J Nucl Med (ISSN: 1125-0135, 1124-3937), 1995 Dec; 39(4Suppl1): 145-149.
Impact Factor: 2.125
Dettagli Esporta in BibTeX Esporta in EndNote
Klain M, Maurea S, Lastoria S, Cuocolo A, Colao A, Salvatore M
Technetium-99m-tetrofosmin imaging of differentiated mixed thyroid cancer (178 visite)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1995 Dec; 36(12): 2248-2251.
Impact Factor: 3.491
Dettagli Esporta in BibTeX Esporta in EndNote
Sijens PE, Knopp MV, Brunetti A, Wicklow K, Alfano B, Bachert P, Sanders JA, Stillman AE, Kett H, Sauter R
1H MR spectroscopy in patients with metastatic brain tumors: A multicenter study (273 visite)
Magn Reson Med (ISSN: 0740-3194, 1522-2594electronic), 1995 Jun; 33(6): 818-826.
Impact Factor: 3.012
Dettagli Esporta in BibTeX Esporta in EndNote
Del Vecchio S, Ciarmiello A, Potena MI, Carriero MV, Mainolfi C, Botti G, Tsuruo T, Salvatore M
Quantitation of P-glycoprotein in sections of human breast carcinoma (214 visite)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1995; 36(5SUPPL.): N/D-N/D.
Impact Factor: 3.491
Dettagli Esporta in BibTeX Esporta in EndNote
Ciarmiello A, Del Vecchio S, Potena MI, Mainolfi C, Carriero MV, Tsuruo T, Marone A, Salvatore M
Tc-99m-SESTAMIBI efflux and P-glycoprotein expression in human breast carcinoma (173 visite)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1995; 36(5SUPPL.): N/D-N/D.
Impact Factor: 3.491
Dettagli Esporta in BibTeX Esporta in EndNote
Carriero MV, Franco P, Del Vecchio S, Massa O, Botti G, D'Aiuto G, Stoppelli MP, Salvatore M
Tissue distribution of soluble and receptor-bound urokinase in human breast cancer using a panel of monoclonal antibodies (299 visite)
Cancer Res (ISSN: 0008-5472, 1538-7445, 1538-7445electronic), 1994 Oct 15; 54(20): 5445-5454.
Impact Factor: 8.426
Dettagli Esporta in BibTeX Esporta in EndNote
Maurea S, Lastoria S, Klain M, Brunetti A, Boscaino A, Lupoli G, Salvatore M
Diagnostic evaluation of thyroid involvement by histiocytosis (205 visite)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1994 Feb; 35(2): 263-265.
Impact Factor: 3.491
Dettagli Esporta in BibTeX Esporta in EndNote
Correale P, Caraglia M, Pepe S, Ricciardi B, Barile C, Montagnani S, Pacelli R, Bianco A, Tagliaferri P
PHORBOL 12-MYRISTATE 13-ACETATE (PMA) INDUCES NEUROENDOCRINE-LIKE DIFFERENTIATION AND REVERSES DOXORUBICIN-RESISTANCE OF HUMAN COLON-CARCINOMA CELLS IN-VITRO (219 visite)
Int J Oncol (ISSN: 1019-6439, 1791-2423electronic, 1019-6439linking), 1994 Feb; 4(2): 423-427.
Impact Factor: 1.181
Dettagli Esporta in BibTeX Esporta in EndNote
Caraglia M, Tagliaferri P, Correale P, Genua G, Pinto A, Del Vecchio S, Esposito G, Bianco AR
CYTOSINE-ARABINOSIDE INCREASES THE BINDING OF I-125 LABELED EPIDERMAL GROWTH-FACTOR AND I-125 TRANSFERRIN AND ENHANCES THE IN-VITRO TARGETING OF HUMAN TUMOR-CELLS WITH ANTI-(GROWTH FACTOR-RECEPTOR) MAB (222 visite)
Cancer Immunol Immunother (ISSN: 0340-7004, 0340-7004linking), 1993 Sep; 37(3): 150-156.
Impact Factor: 1.269
Dettagli Esporta in BibTeX Esporta in EndNote
Caraglia M, Tagliaferri P, Correale P, Genua G, Pinto A, Del Vecchio S, Esposito G, Bianco AR
Cytosine arabinoside increases the binding of 125I-labelled epidermal growth factor and 125I-transferrin and enhances the in vitro targeting of human tumour cells with anti-(growth factor receptor) mAb (115 visite)
Cancer Immunol Immunother (ISSN: 0340-7004linking), 1993 Aug; 37 (3 ): 150-156.
Impact Factor: 4.293
Dettagli Esporta in BibTeX Esporta in EndNote
Del Vecchio S, Stoppelli MP, Carriere MV, Fonti R, Massa O, Li PY, Botti G, Cerra M, D'Aiuto G, Esposito G, Salvatore M
Human urokinase receptor concentration in malignant and benign breast tumors by in vitro quantitative autoradiography: Comparison with urokinase levels (177 visite)
Cancer Res (ISSN: 0008-5472, 1538-7445, 1538-7445electronic), 1993 Jul 1; 53(13): 3198-3206.
Impact Factor: 8.426
Dettagli Esporta in BibTeX Esporta in EndNote
Arena G, Bindoni M, Cardile V, Maccarrone G, Riello MC, Rizzarelli E, Sciuto S
Cytotoxic and cytostatic activity of copper(II) complexes. Importance of the speciation for the correct interpretation of the in vitro biological results (378 visite)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 1993 Apr 1; 50(1): 31-45.
Impact Factor: 1.342
Dettagli Esporta in BibTeX Esporta in EndNote
Maglione D, Guerriero V, Viglietto G, Ferraro MG, Aprelikova O, Alitalo K, Del Vecchio S, Lei KJ, Chou JY, Persico MG
Two alternative mRNAs coding for the angiogenic factor, placenta growth factor (PlGF), are transcribed from a single gene of chromosome 14 (331 visite)
Oncogene (ISSN: 0950-9232, 1476-5594), 1993; 8(4): 925-931.
Impact Factor: 6.772
Dettagli Esporta in BibTeX Esporta in EndNote
Del Vecchio S, Stoppelli P, Fonti R, Carriero MV, Li P, Salvatore M
Urokinase and urokinase receptor overexpression in breast carcinoma as compared to benign lesions (141 visite)
Meetingproceedings Of The American Association For Cancer Research Annual (ISSN: 0197-016x), 1993; 34(0): N/D-N/D.
Impact Factor: 0
Dettagli Esporta in BibTeX Esporta in EndNote
Sofia M, Del Vecchio S, Petrillo A, Mormile M, Salvatore M, Carratù L
Endobronchial deposition of radioactive monoclonal antibody in patients with inoperable non-small-cell carcinoma of the lung [4] (195 visite)
Chest (ISSN: 0012-3692), 1992 Nov; 102(5): 1632-1634.
Impact Factor: 2.341
Dettagli Esporta in BibTeX Esporta in EndNote
Lakshmanan M, Reynolds JC, Del Vecchio S, Merino MJ, Norton JA, Robbins J
PELVIC RADIOIODINE UPTAKE IN A RECTAL WALL TERATOMA AFTER THYROIDECTOMY FOR PAPILLARY CARCINOMA (181 visite)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1992 Oct; 33(10): 1848-1850.
Impact Factor: 3.491
Dettagli Esporta in BibTeX Esporta in EndNote
Scala S, Pacelli R, Iaffaioli RV, Normanno N, Pepe S, Frasci G, Genua G, Tsuruo T, Tagliaferri P, Bianco AR
Reversal of adriamycin resistance by recombinant α-interferon in multidrug-resistant human colon carcinoma LoVo-doxorubicin cells (412 visite)
Cancer Res (ISSN: 0008-5472, 1538-7445, 1538-7445electronic), 1991 Sep 15; 51(18): 4898-4902.
Impact Factor: 8.426
Dettagli Esporta in BibTeX Esporta in EndNote
Camera L, Del Vecchio S, Petrillo A, Esposito G, Frasci G, Iaffaioli RV, Bianco AR, Salvatore M
Evaluation of therapeutic response using iodine-131-B72. 3 monoclonal antibody in patients with ovarian carcinoma (327 visite)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1991 Apr; 18(4): 269-273.
Impact Factor: 2.692
Dettagli Esporta in BibTeX Esporta in EndNote
Iaffaioli RV, Frasci G, Facchini G, Pagliarulo C, Pacelli R, Scala S, Espinosa A, Bianco AR
Alpha 2b interferon (IFN) by intraperitoneal administration via temporary catheter in ovarian cancer. Preliminary data (312 visite)
Eur J Gynaecol Oncol (ISSN: 0392-2936), 1991; 12(1): 69-75.
Impact Factor: 0.397
Dettagli Esporta in BibTeX Esporta in EndNote
Del Vecchio S, Camera L, Petrillo A, Esposito G, Frasci G, Iaffaioli RV, Bianco AR, Salvatore M
Clinical studies with B72. 3 in ovarian cancer and probe-guided tumor localization (277 visite)
Nucl Med Biol (ISSN: 0883-2897, 0969-8051), 1991; 18(1): 85-87.
Impact Factor: 1.042
Dettagli Esporta in BibTeX Esporta in EndNote
Del Vecchio S, Mansi L, Petrillo A, Camera L, Sofia M, Marra A, Carratú L, Salvatore M
Endobronchial administration of iodine-131 B72. 3 monoclonal antibody in patients with lung cancer (190 visite)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1991; 18(2): 129-132.
Impact Factor: 2.692
Dettagli Esporta in BibTeX Esporta in EndNote
Papa V, Reese CC, Brunetti A, Vigneri R, Siiteri PK, Goldfine ID
Progestins increase insulin receptor content and insulin stimulation of growth in human breast carcinoma cells (345 visite)
Cancer Res (ISSN: 0008-5472, 1538-7445, 1538-7445electronic), 1990 Dec 15; 50(24): 7858-7862.
Impact Factor: 8.426
Dettagli Esporta in BibTeX Esporta in EndNote
Valenza V, Maussier ML, D'Errico G, Lemmo GF, Frontera D, Ferrante A, Saletnich I, Valli A, Quarantelli M
Cancer of the pancreas and the periampullary region: The usefulness of tumor marker products with the monoclonal antibody technique (181 visite)
J Nucl Med Allied Sci (ISSN: 0392-0208), 1990 Oct; 34(4SUPPL.): 131-134.
Impact Factor: 1.91
Dettagli Esporta in BibTeX Esporta in EndNote
Steis RG, Carrasquillo JA, Mccabe R, Bookman MA, Reynolds JC, Larson SM, Smith JW, Clark JW, Dailey V, Del Vecchio S
Toxicity, immunogenicity, and tumor radioimmunodetecting ability of two human monoclonal antibodies in patients with metastatic colorectal carcinoma (191 visite)
J Clin Oncol (ISSN: 0732-183x, 0732-183xlinking), 1990 Mar; 8(3): 476-490.
Impact Factor: 7.878
Dettagli Esporta in BibTeX Esporta in EndNote
Reynolds JC, Del Vecchio S, Sakahara H, Lora ME, Carrasquillo JA, Neumann RD, Larson SM
ANTI-MURINE ANTIBODY RESPONSE TO MOUSE MONOCLONAL ANTIBODIES CLINICAL FINDINGS AND IMPLICATIONS (417 visite)
Nucl Med Biol (ISSN: 0969-8051, 0883-2897), 1989; 16(2): 121-125.
Impact Factor: 1.042
Dettagli Esporta in BibTeX Esporta in EndNote
Salvatore M, Lastoria S, Del Vecchio S, Mansi L
Detection of colon cancer with radiolabelled monoclonal antibodies (219 visite)
Nucl Med Biol (ISSN: 0883-2897, 0969-8051), 1989; 16(2): 103-104.
Impact Factor: 1.042
Dettagli Esporta in BibTeX Esporta in EndNote
Alfano B, Coucourde F, Malgieri F, Ragozzino A
PET/CT and radiotherapy (1970 visite)
Q J Nucl Med Mol Imaging, 1980 Oct; 50(1): 4-14.
Impact Factor: 0
Dettagli Esporta in BibTeX Esporta in EndNote
Romano M, Cerra M, Salvatore M, Onorati A
Effects of ionizing radiations on the activity of valyl tRNA synthetase isolated from rat liver and from Morris hepatoma 7777 (635 visite)
Tumori (ISSN: 0300-8916, 0300-8916print, 0300-8916linking), 1974 Jul; 60(4): 301-306.
Impact Factor: 0.408
Dettagli Esporta in BibTeX Esporta in EndNote
200 Records (174 escludendo Abstract e Conferenze).
Impact factor totale: 619.439 (536.35 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 642.763 (551.133 escludendo Abstract e Conferenze).
Impact factor totale: 619.439 (536.35 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 642.763 (551.133 escludendo Abstract e Conferenze).
Esporta in BibTeX Esporta in EndNote
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