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Imaging of brain TSPO expression in a mouse model of amyotrophic lateral sclerosis with F-DPA-714 and micro-PET/CT (429 visite) (PDF privato 140 visite)

Gargiulo S, Anzilotti S, Coda ARD, Gramanzini M, Greco A, Panico M, Vinciguerra A, Zannetti A, Vicidomini C, Dolle F, Pignataro G, Quarantelli M, Annunziato L, Brunetti A, Salvatore M, Pappata S

Eur J Nucl Med Mol Imaging (ISSN: 1619-7089electronic, 1619-7070linking, 1619-7070print), 2016 Jan 27; N/D: 1-12.

Tipo di articolo: Journal Article,

Impact factor: 7.277

Impact factor a 5 anni: 6.218


Parole chiave: 18f-Dpa-714, Sod1g93a, Tspo, Mice, Pet Ct,

Url: https://www2.scopus.com/inward/record.uri?eid=2-s2.0-84955614300&partnerID=40&md5=2184058c348d2cba42ba2dd9fb3b1a01

Purpose: To evaluate the feasibility and sensitivity of 18F-DPA-714 for the study of microglial activation in the brain and spinal cord of transgenic SOD1G93A mice using high-resolution PET/CT and to evaluate the Iba1 and TSPO expression with immunohistochemistry. Methods: Nine symptomatic SOD1G93A mice (aged 117 ± 12.7 days, clinical score range 1 – 4) and five WT SOD1 control mice (aged 108 ± 28.5 days) underwent 18F-DPA-714 PET/CT. SUV ratios were calculated by normalizing the cerebellar (rCRB), brainstem (rBS), motor cortex (rMCX) and cervical spinal cord (rCSC) activities to that of the frontal association cortex. Two WT SOD1 and six symptomatic SOD1G93A mice were studied by immunohistochemistry. Results: In the symptomatic SOD1G93A mice, rCRB, rBS and rCSC were increased as compared to the values in WT SOD1 mice, with a statistically significantly difference in rBS (2.340 ± 0.784 vs 1.576 ± 0.287, p = 0.014). Immunofluorescence studies showed that TSPO expression was increased in the trigeminal, facial, ambiguus and hypoglossal nuclei, as well as in the spinal cord, of symptomatic SOD1G93A mice and was colocalized with increased Iba1 staining. Conclusion: Increased 18F-DPA-714 uptake can be detected with high-resolution PET/CT in the brainstem of transgenic SOD1G93A mice, a region known to be a site of degeneration and increased microglial activation in amyotrophic lateral sclerosis, in agreement with increased TSPO expression in the brainstem nuclei shown by immunostaining. Therefore, 18F-DPA-714 PET/CT might be a suitable tool to evaluate microglial activation in the SOD1G93A mouse model. © 2016 Springer-Verlag Berlin Heidelberg
*** IBB - CNR ***

Institute of Biostructure and Bioimaging, National Research Council, Via T. De Amicis 95, 80145, Naples, Italy., Ceinge Biotecnologie Avanzate s. c. a r. l., Via G. Salvatore 486, 80145, Naples, Italy., IRCCS SDN, Via E. Gianturco 113, 80143, Naples, Italy., Department of Advanced Biomedical Sciences, University "Federico II", Via S. Pansini 5, 80131, Naples, Italy., Division of Pharmacology, Department of Neuroscience, Reproductive and Dentistry Sciences, School of Medicine, University "Federico II", Via S. Pansini 5, 80131, Naples, Italy., CEA, Institute for Biomedical Imaging, 4 Place du General Leclerc, 91401, Orsay, France., Institute of Biostructure and Bioimaging, National Research Council, Via T. De Amicis 95, 80145, Naples, Italy. sabina.pappata@ibb.cnr.it.,
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A voxel-based morphometry study of disease severity correlates in relapsing– remitting multiple sclerosis (dominio pubblico) (82 visite)
An Ontology Approach for Classification of Abnormal White Matter in Patients with Multiple Sclerosis (accesso riservato) (124 visite)
Automated Segmentation and Measurement of Global White Matter Lesion Volume in Patients With Multiple Sclerosis (accesso riservato) (407 visite)
BDNF Val66Met polymorphism and brain volumes in multiple sclerosis (accesso riservato) (104 visite)
Brain atrophy and lesion load in a large population of patients with multiple sclerosis (accesso riservato) (128 visite)
Brain atrophy evolution and lesion load accrual in multiple sclerosis: a 2-year follow-up study (accesso riservato) (126 visite)
Brain tissue volume changes in relapsing-remitting multiple sclerosis: correlation with lesion load (dominio pubblico) (100 visite)
Changes in magnetic resonance imaging disease measures over 3 years in mildly disabled patients with relapsing-remitting multiple sclerosis receiving interferon beta 1a in the COGnitive Impairment in MUltiple Sclerosis (COGIMUS) study (dominio pubblico) (87 visite)
Clinical and magnetic resonance imaging predictors of disease progression in multiple sclerosis: a nine-year follow-up study (accesso riservato) (113 visite)
Clinical Applications of Imaging Disease Burden in Multiple Sclerosis - MRI and Advanced Imaging Techniques (accesso riservato) (108 visite)
Clinical Evaluation of a New Concept: Resting Myocardial Perfusion Heterogeneity Quantified by Markovian Analysis of PET Identifies Coronary Microvascular Dysfunction and Early Atherosclerosis in 1,034 Subjects (accesso riservato) (83 visite)
Correlation between fatigue and brain atrophy and lesion load in multiple sclerosis patients independent of disability (accesso riservato) (102 visite)
Early development of multiple sclerosis is associated with progressive grey matter atrophy in patients presenting with clinically isolated syndromes (dominio pubblico) (82 visite)
Global and regional brain atrophy is associated with low or retrograde facial vein flow in multiple sclerosis (dominio pubblico) (44 visite)
Grey matter loss in relapsing–remitting multiple sclerosis: A voxel-based morphometry study (accesso riservato) (105 visite)
Imaging of brain perfusion in multiple sclerosis and neurodegenerative diseases: association with endothelial factors. An interim analysis (dominio pubblico) (92 visite)
Imaging of brain TSPO expression in a mouse model of amyotrophic lateral sclerosis with 18F-DPA-714 and micro-PET/CT (accesso riservato) (140 visite)
Internal Jugular Vein Blood Flow in Multiple Sclerosis Patients and Matched Controls (dominio pubblico) (92 visite)
Measurement of Whole-Brain Atrophy in Multiple Sclerosis (accesso riservato) (90 visite)
Predictive factors of neutralizing antibodies development in relapsing-remitting multiple sclerosis patients on interferon Beta-1b therapy (accesso riservato) (82 visite)
Quantitative assessment of blood-brain barrier permeability in multiple sclerosis using 68-Ga-EDTA and positron emission tomography (dominio pubblico) (102 visite)
The measurement and clinical relevance of brain atrophy in multiple sclerosis (accesso riservato) (80 visite)
Thermus thermophilus as source of thermozymes for biotechnologicalapplications: homologous expression and biochemical characterization of anα-galactosidase. (dominio pubblico) (47 visite)
Vascular Disease in Multiple Sclerosis: A Real Thing? (dominio pubblico) (74 visite)
Vascular Disease in Patients with Multiple Sclerosis: A Review (dominio pubblico) (71 visite)
White matter lesion detection in multiple sclerosis: improved interobserver concordance with multispectral MRI display (accesso riservato) (95 visite)
Whole-brain atrophy in multiple sclerosis measured by two segmentation processes from various MRI sequences (accesso riservato) (91 visite)


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* Autocrine signals increase Ovine Mesenchymal Stem Cells migration through Aquaporin-1 and CXCR4 overexpression (26 visite)
Pelagalli A, Nardelli A, Lucarelli E, Zannetti A, Brunetti A
J Cell Physiol (ISSN: 1097-4652electronic, 0021-9541linking), 2018 Jan 18; N/D: N/D-N/D.
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* Global and regional brain atrophy is associated with low or retrograde facial vein flow in multiple sclerosis (40 visite) (PDF 44 visite)
Jakimovski D, Marr K, Mancini M, Caprio MG, Gandhi S, Bergsland N, Paunkoski I, Hagemeier J, Chandra A, Weinstock-guttman B, Zivadinov R
Veins And Lymphatics, 2017 Sep; 6: N/D-N/D.
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* Predictors of Asymptomatic Radiation-induced Abdominal Atherosclerosis (40 visite)
Cella L, Liuzzi R, Romanelli P, Conson M, D'Avino V, Ottaviano M, Damiano V, Palmieri G, Pacelli R, Mancini M
Clin Oncol (ISSN: 1433-2981electronic, 0936-6555linking), 2017 Aug 10; N/D: N/D-N/D.
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* Centralized and local color Doppler ultrasound reading agreement for diagnosis of the chronic cerebrospinal venous insufficiency in patients with Multiple Sclerosis (38 visite)
Caprio MG, Marr K, Gandhi S, Jakimovski D, Hagemeier J, Weinstock-guttman B, Zivadinov R, Mancini M
Curr Neurovasc Res (ISSN: 1875-5739electronic, 1567-2026linking), 2017 Jul 17; N/D: N/D-N/D.
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* Thermus thermophilus as source of thermozymes for biotechnologicalapplications: homologous expression and biochemical characterization of anα-galactosidase (26 visite) (PDF 47 visite)
Aulitto M, Fusco S, Fiorentino G, Limauro D, Pedone E, Bartolucci S, Contursi P
Microbial Cell Fact, 2017 Feb; N/D: N/D-N/D.
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* Grey: white matter ratio at diagnosis and the risk of 10-year multiple sclerosis progression (77 visite)
Moccia M, Quarantelli M, Lanzillo R, Cocozza S, Carotenuto A, Carotenuto B, Alfano B, Prinster A, Triassi M, Nardone A, Palladino R, Brunetti A, Brescia Morra V
Eur J Neurol (ISSN: 1468-1331electronic, 1351-5101linking), 2017 Jan; 24(1): 195-204.
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* Growth hormone/IGF-1 axis longitudinal evaluation in clinically isolated syndrome patients on interferon beta-1b therapy: stimulation tests and correlations with clinical and radiological conversion to multiple sclerosis (51 visite)
Lanzillo R, Di Somma C, Quarantelli M, Carotenuto A, Pivonello C, Moccia M, Cianflone A, Marsili A, Puorro G, Sacca F, Russo CV, De Luca Picione C, Ausiello F, Colao A, Brescia Morra V
Eur J Neurol (ISSN: 1468-1331electronic, 1351-5101linking), 2017; 24(2): 446-449.
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* Immunometabolic profiling of patients with multiple sclerosis identifies new biomarkers to predict disease activity during treatment with interferon beta-1a (31 visite)
Lanzillo R, Carbone F, Quarantelli M, Bruzzese D, Carotenuto A, De RosaV, Colamatteo A, Micillo T, De Luca Picione C, Saccà F, De Rosa A, Moccia M, Brescia Morra V, Matarese G
Clin Immunol, 2017; 183: 249-253.
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* Vascular Disease in Multiple Sclerosis: A Real Thing? (60 visite) (PDF 74 visite)
Caprio MG, Mancini M
Blood Disorders & Transfusion, 2016 Oct; 7: N/D-N/D.
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* No evidence for an effect on brain atrophy rate of atorvastatin add-on to interferon beta1a therapy in relapsing-remitting multiple sclerosis (the ARIANNA study) (183 visite)
Lanzillo R, Quarantelli M, Pozzilli C, Trojano M, Amato MP, Marrosu MG, Francia A, Florio C, Orefice G, Tedeschi G, Bellantonio P, Annunziata P, Grimaldi LM, Comerci M, Brunetti A, Bonavita V, Alfano B, Marini S, Brescia Morra V
Mult Scler (ISSN: 1352-4585linking, 1477-0970electronic), 2016 Aug; 22(9): 1163-1173.
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* Cloning, expression and purification of the complete domain of the eta-carbonic anhydrase from Plasmodium falciparum (52 visite)
Del Prete S, De Luca V, De Simone G, Supuran CT, Capasso C
J Enzyme Inhib Med Chem (ISSN: 1475-6374electronic, 1475-6366linking), 2016 Jun; 31(sup4): 54-59.
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* Lack of correlation between extracranial venous abnormalities and multiple sclerosis: a quantitative MRI study (67 visite)
Cocozza S, Canna A, Lanzillo R, Russo C, Postiglione E, Liuzzi R, Vastola M, Brunetti A, Salvatore M, Brescia Morra V, Palma G, Tedeschi E
The British Institute Of Radiology, 2016 Jun; N/D: N/D-N/D.
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* No association of extra-cranial neous abnormalities and clinical outcomes in multiple sclerosis patients over 5 years (67 visite)
Gandhi S, Mancini M, Marr K, Caprio MG, Jakimovski D, Chandra A, Hagemeier J, Weinstock-guttman B, Zivadinov R
6th Annual Meeting Of The International Society For Neurovascular Disease, 2016 Apr; N/D: N/D-N/D.
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* Overexpression of human SOD1 in VDAC1-less yeast restores mitochondrial functionality modulating beta-barrel outer membrane protein genes (94 visite)
Magri A, Di Rosa MC, Tomasello MF, Guarino F, Reina S, Messina A, De Pinto V
Biochim Biophys Acta (ISSN: 0005-2728, 0006-3002print), 2016 Mar 4; 1857(6): 789-798.
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* Animal Care in a Mouse Model of Amyotrophic Lateral Sclerosis Studied with [18F]DPA-714 Micro-PET/CT (44 visite)
Gargiulo S, Gramanzini M, Coda ARD, Megna R, Panico M, Mancini M, Pappata S
Comparative Medicine, 2016 Feb; 66(1): 76-76.
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* Quality of life and cognitive functions in early onset multiple sclerosis (67 visite)
Lanzillo R, Chiodi A, Carotenuto A, Magri V, Napolitano A, Liuzzi R, Costabile T, Rainone N, Freda MF, Valerio P, Brescia Morra V
Eur J Paediatr Neurol (ISSN: 1090-3798, 1532-2130), 2016 Jan; 20(1): 158-163.
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* Vascular Disease in Patients with Multiple Sclerosis: A Review (87 visite) (PDF 71 visite)
Caprio MG, Russo C, Giugliano A, Ragucci M, Mancini M
J Vasc Med Surg, 2016; 4: 1-12.
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* Variants Within TSC2 Exons 25 and 31 are Very Unlikely to Cause Clinically Diagnosable Tuberous Sclerosis (78 visite)
Ekong R, Nellist M, Hoogeveen-westerveld M, Wentink M, Panzer J, Sparagana S, Emmett W, Dawson NL, Malinge MC, Nabbout R, Carbonara C, Barberis M, Padovan S, Futema M, Plagnol V, Humphries SE, Migone N, Povey S
Hum Mutat (ISSN: 1098-1004electronic, 1059-7794linking), 2015 Dec 25; N/D: N/D-N/D.
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* Combination of Abeta Secretion and Oxidative Stress in an Alzheimer-Like Cell Line Leads to the Over-Expression of the Nucleotide Excision Repair Proteins DDB2 and XPC (84 visite)
Forestier A, Douki T, De Rosa V, Beal D, Rachidi W
Int J Mol Sci (ISSN: 1422-0067linking, 1422-0067electronic, 1661-6596), 2015 Jul 30; 16(8): 17422-17444.
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* A composite enhancer regulates p63 gene expression in epidermal morphogenesis and in keratinocyte differentiation by multiple mechanisms (195 visite)
Antonini D, Sirico A, Aberdam E, Ambrosio R, Campanile C, Fagoonee S, Altruda F, Aberdam D, Brissette JL, Missero C
Nucleic Acids Res (ISSN: 0305-1048, 1362-4962, 1362-4962electronic), 2015 Jan; 43(2): 862-874.
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* The combined use of conventional MRI and MR spectroscopic imaging increases the diagnostic accuracy in amyotrophic lateral sclerosis (82 visite)
Cervo A, Cocozza S, Saccà F, Giorgio SM, Morra VB, Tedeschi E, Marsili A, Vacca G, Palma V, Brunetti A, Quarantelli M
European Journal Of Radiology (ISSN: 0720-048x), 2015 Jan; 84(1): 151-157.
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* CEREBRAL CIRCULATION IN PATIENTS WITH MULTIPLE SCLEROSIS. A COLOR-DOPPLER STUDY OF EXTRACRANIAL ARTERIAL AND VENOUS VESSELS (84 visite)
Cervo A, Caprio MG, Ragucci M, Mancini M
Veins And Lymphatics (ISSN: 2279-7483), 2015; 4(s1): 12-12.
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* Correlation between Neck Venous Drainage and Multiple Sclerosis (74 visite)
Cocozza S, Canna A, Lanzillo R, Palma G, Postiglione E, Russo C, Borrelli P, Brescia Morra V, Brunetti A, Salvatore M, Tedeschi E
Rsna 101st Scientific Assembly And Annual Meeting, 2015; N/D: N/D-N/D.
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* Expression and Localization of Aquaporin-1 Along the Intestine of Colostrum Suckling Buffalo Calves (60 visite)
De Luca A, Vassalotti G, Pelagalli A, Pero ME, Squillacioti C, Mirabella N, Lombardi P, Avallone L
Journal Of Veterinary Medicine Series C (ISSN: 0340-2096), 2015; 44(5): 391-400.
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* INCREASED ENDOTHELIN-1 SERUM LEVELS IN PATIENTS WITH MULTIPLE SCLEROSIS (129 visite)
Cianflone A, Criscuolo C, Lanzillo R, Liuzzi R, Mancini M, Tedeschi E, Postiglione E, Vacca G, Vacchiano V, Moccia M, VastoLa M, Puorro G, Marsili A, Incoronato M, Salvatore M, Brescia-Morra V
Veins And Lymphatics (ISSN: 2279-7483), 2015; 4(s1): 22-22.
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* Lesion load may predict long-term cognitive dysfunction in multiple sclerosis patients (90 visite)
Patti F, De Stefano M, Lavorgna L, Messina S, Chisari CG, Ippolito D, Lanzillo R, Vacchiano V, Realmuto S, Valentino P, Coniglio G, Buccafusca M, Paolicelli D, D'Ambrosio A, Montella P, Morra VB, Savettieri G, Alfano B, Gallo A, Simone I, Viterbo R, Zappia M, Bonavita S, Tedeschi G
Plos One (ISSN: 1932-6203, 1932-6203electronic), 2015; 10(3): N/D-N/D.
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* SPG5 and multiple sclerosis: Clinical and genetic overlap? (63 visite)
Criscuolo C, Carbone R, Lieto M, Peluso S, Guacci A, Filla A, Quarantelli M, Lanzillo R, Brescia Morra V, De Michele G
Acta Neurologica Scandinavica (ISSN: 0001-6314, 1600-0404), 2015; 133(6): 410-414.
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* Visceral adiposity and subclinical atherosclerosis in healthy young men (46 visite)
Clemente G, Mancini M, Giacco R, Tornatore A, Ragucci M, Riccardi G
International Journal Of Food Sciences And Nutrition (ISSN: 0963-7486, 1465-3478electronic, 0963-7486linking), 2015; 66(4): 466-470.
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* CXCR4 expression affects overall survival of HCC patients whereas CXCR7 expression does not (78 visite)
Neve Polimeno M, Ierano C, D'Alterio C, Losito NS, Napolitano M, Portella L, Scognamiglio G, Tatangelo F, Maria Trotta A, Curley S, Costantini S, Liuzzi R, Izzo F, Scala S
Cellular And Molecular Immunology (ISSN: 1672-7681), 2014 Nov 3; 12(4): 474-482.
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* Diagnostic challenges of Parkinsonism occurring in multiple sclerosis (51 visite)
Moccia M, Erro R, Montella S, Carotenuto A, Pappata S, Orefice G
Acta Neurol Belg (ISSN: 0300-9009), 2014 Oct 12; N/D: N/D-N/D.
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* CBX7 gene expression plays a negative role in adipocyte cell growth and differentiation (64 visite)
Forzati F, Federico A, Pallante P, Colamaio M, Esposito F, Sepe R, Gargiulo S, Luciano A, Arra C,  Palma G, Bon G, Bucher S, Falcioni R, Brunetti A, Battista S, Fedele M, Fusco A
Biology Open (ISSN: 2046-6390), 2014 Sep 15; 3(9): 871-879.
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* Deletion of exons 1-3 of the MEN1 gene in a large Italian family causes the loss of menin expression (90 visite)
Zatelli MC, Tagliati F, Di Ruvo M, Castermans E, Cavazzini L, Daly AF, Ambrosio MR, Beckers A, degli Uberti E
Fam Cancer Kluwer Academic Publishers (ISSN: 1389-9600), 2014 Jun; 13(2): 273-280.
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* Brain atrophy in Relapsing-remitting multiple sclerosis patients treated with interferon-beta and atorvastatin (The ARIANNA study) (153 visite)
Lanzillo R, Quarantelli M, Veria V, Orefice G, Marrosu MG, Trojano M, Amato MP, Francia AM, Florio C, Tedeschi G, Bellantonio P, Annunziata P, Comerci M, Brunetti A, Bonavita V, Alfano B, Marini S, Pozzilli C, Morra VB
J Neurol (ISSN: 0340-5354, 1432-1459, 1432-1459electronic), 2014 May 31; 261(Suppl.1): S43-S43.
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* Brain atrophy in relapsing-remitting multiple sclerosis patients treated with interferon-beta and atorvastatin (The ARIANNA study) (133 visite)
Lanzillo R, Quarantelli M, Veria V, Orefice G, Marrosu MG, Trojano M, Amato MP, Francia AM, Florio C, Tedeschi G, Bellantonio P, Annunziata P, Comerci M, Brunetti A, Bonavita V, Alfano B, Marini S, Pozzilli C, Morra VB
Eur J Neurol (ISSN: 1351-5101, 1468-1331electronic), 2014 May; 21(S.I.Suppl.1): 58-58.
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* Imaging Of Brain Perfusion In Multiple Sclerosis And Neurodegenerative Diseases: Association With Endothelial Factors. An Interim Analysis (81 visite) (PDF 92 visite)
Tedeschi E, Lanzillo R, Mancini M, Russo C, Cianflone A, Liuzzi R, Cocozza S, Postiglione E, Palma G, Caprio MG, Incoronato MR, Criscuolo C, Brescia Morra V, Salvatore M
2014 Joint Actrims-Ectrims Meeting, 2014 Apr 28; N/D: N/D-N/D.
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* Internal jugular vein blood flow in multiple sclerosis patients and matched controls (107 visite) (PDF 92 visite)
Mancini M, Lanzillo R, Liuzzi R, Di Donato O, Ragucci M, Monti S, Salvatore E, Morra VB, Salvatore M
Plos One (ISSN: 1932-6203, 1932-6203electronic), 2014 Mar 27; 9(3): e92730-e92730.
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* SIRT1 gene expression upon genotoxic damage is regulated by APE1 through nCaRE-promoter elements (137 visite)
Antoniali G, Lirussi L, D'Ambrosio C, Dal Piaz F, Vascotto C, Casarano E, Marasco D, Scaloni A, Fogolari F, Tell G
Molecular Biology Of The Cell (ISSN: 1059-1524), 2014 Feb 15; 25(4): 532-547.
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* Clinical And Magnetic Resonance Imaging Predictors Of Disease Progression In Multiple Sclerosis: A Nine-Year Follow-Up Study (157 visite) (PDF 113 visite)
Lavorgna L, Bonavita S, Ippolito D, Lanzillo R, Salemi G, Patti F, Valentino P, Coniglio G, Buccafusca M, Paolicelli D, D'Ambrosio A, Bresciamorra V, Savettieri G, Zappia M, Alfano B, Gallo A, Simone I, Tedeschi G
Mult Scler (ISSN: 1352-4585, 1352-2458, 1477-0970), 2014 Feb; 20(2): 220-226.
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* Estimate of the accelerated proliferation by protein tyrosine phosphatase (PTEN) over expression in postoperative radiotherapy of head and neck squamous cell carcinoma (94 visite)
Pedicini P, Fiorentino A, Improta G, Nappi A, Salvatore M, Storto G
Clin Transl Oncol (ISSN: 1699-048x), 2013 Nov; 15(11): 919-924.
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* Imaging of brain TSPO expression in a mouse model of stroke with [18F]DPA-714 and micro-PET (86 visite)
Vicidomini C, Vinciguerra A, Greco A, Panico M, Gargiulo S, Gramanzini M, Coda ARD, Pignataro G, Quarantelli M, Tavitian B, Dollé F, Brunetti A, Salvatore M, Annunziato L, Pappata S
Eur J Nucl Med Mol Imaging (ISSN: 1619-7070, 1619-7089, 0340-6997), 2013 Oct; 40: 450-450.
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* Management of multiple sclerosis patients after the 24th Natalizumab course: the Ty-STOP study (69 visite)
Clerico M, De Mercanti S, Versino E, Piazza F, Gned D, Brescia Morra V, Lanzillo R, Amato L, Quarantelli M, Ghezzi A, Bianchi A, Baroncini D, Salemi G, Realmuto S, Ferro MT, Vitetta F, Donghia M, Paolicelli D, Trojano M, Durelli L
Mult Scler (ISSN: 1352-4585, 1477-0970, 1352-4585linking), 2013 Oct; 19(11): N/D-N/D.
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* Observational case-control study of the prevalence of chronic cerebrospinal venous insufficiency in multiple sclerosis: results from the CoSMo study (64 visite)
Comi G, Battaglia MA, Bertolotto A, Del Sette M, Ghezzi A, Malferrari G, Salvetti M, Sormani MP, Tesio L, Stolz E, Zaratin P, Mancardi G, Mancini M
Mult Scler (ISSN: 1477-0970, 1352-4585, 1352-4585linking), 2013 Oct; 19(11): 1508-1517.
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* Endothelial function as a marker of pre-clinical atherosclerosis: assessment techniques and clinical implications (67 visite)
Ruggiero D, Paolillo S, Ratta GD, Mariniello A, Formisano T, Pellegrino AM, Filardi PP
Monaldi Archives For Chest Disease = Archivio Monaldi Per Le Malattie Del Torace / Fondazione Clinica Del Lavoro Irccs [and] Istituto Di Clinica Tisiologica E Malattie Apparato Respiratorio Universita Di Napoli Secondo Ateneo, 2013 Sep; 80(3): 106-110.
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* Thymidine Kinase-Mediated Shut Down of Bone Morphogenetic Protein-4 Expression Allows Regulated Bone Production (91 visite)
Lombardo B, Rocco T, Esposito MT, Cantilena B, Gargiulo S, Greco A, Montanaro D, Brunetti A, Pastore L
Current Gene Therapy (ISSN: 1566-5232, 1875-5631), 2013 Jun 1; 13(3): 202-210.
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* Natalizumab is effective in multiple sclerosis patients switching from other disease modifying therapies in clinical practice (50 visite)
Lanzillo R, Bonavita S, Quarantelli M, Vacca G, Lus G, Amato L, Carotenuto A, Tedeschi G, Orefice G, Brescia Morra V
Neurol Sci (ISSN: 1590-1874, 1590-0187, 1590-3478), 2013 Apr; 34(4): 521-528.
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* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of the l, d-transpeptidase LdtMt1 from Mycobacterium tuberculosis (97 visite)
Correale S, Ruggiero A, Pedone E, Berisio R
Communicationsacta Crystallographica Section F Structural Biology And Crystallization (ISSN: 1744-3091, 1744-4309), 2013 Mar 1; 69(3): 253-256.
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* Chronic cerebrospinal venous insufficiency in multiple sclerosis: a highly prevalent age-dependent phenomenon (87 visite)
Lanzillo R, Mancini M, Liuzzi R, Di Donato O, Salvatore E, Maglio V, Vacca G, Amato L, D'Anna G, Brunetti A, Brescia Morra V
Bmc Neurol (ISSN: 1471-2377), 2013 Feb 13; 13: 20-20.
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* Sphingosine Kinase 1 Overexpression Contributes to Cetuximab Resistance in Human Colorectal Cancer Models (117 visite)
Rosa R, Marciano R, Malapelle U, Formisano L, Nappi L, D'Amato C, D'Amato V, Damiano V, Marf G, Del Vecchio S, Zannetti A, Greco A, De Stefano A, Carlomagno C, Veneziani BM, Troncone G, De Placido S, Bianco R
Clin Cancer Res (ISSN: 1078-0432, 1078-0432linking), 2013 Jan 1; 19(1): 138-147.
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* Italian Multicentre Observational Study Of The Prevalence Of Ccsvi In Multiple Sclerosis (cosmo Study): Rationale, Design, And Methodology (60 visite)
Comi G, Battaglia MA, Bertolotto A, Del Sette M, Ghezzi A, Malferrari G, Salvetti M, Sormani MP, Tesio L, Stolz E, Mancardi G, Mancini M
Neurol Sci, 2013 Jan; N/D: N/D-N/D.
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* Natalizumab vs interferon beta 1a in relapsing-remitting multiple sclerosis: A head-to-head retrospective study (85 visite)
Lanzillo R, Quarantelli M, Bonavita S, Ventrella G, Lus G, Vacca G, Prinster A, Orefice G, Tedeschi G, Brescia Morra V
Acta Neurologica Scandinavica (ISSN: 0001-6314, 1600-0404), 2012 Nov; 126(5): 306-314.
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* Efficacy, Safety And Tolerability Of Atorvastatin In Patients With Relapsing-Remitting Multiple Sclerosis In Treatment With Interferon-Beta (arianna): A Multicentre, Randomised, Double-Blind, Placebo-Controlled, Parallel-Group-Study, Lyon. France (132 visite)
Brescia Morra V, Alfano B, Lanzillo R, Quarantelli M, Comerci M, Marini S, Vacca G, Amato MP, Trojano M, Brunetti A, Pozzilli C
Proceedings Of The 23rd Ectrims Meeting Lyon France, 2012 Oct 10; AbstractBook: 477-477.
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* Efficacy, safety and tolerability of Atorvastatin in patients with Relapsing-remitting multiple sclerosis in treAtment with INterferoN-beta (ARIANNA): a multicentre, randomised, double-blind, placebo-controlled, parallel-group-study (121 visite)
Brescia Morra V, Alfano B, Lanzillo R, Quarantelli M, Comerci M, Marini S, Vacca G, Amato MP, Trojano M, Brunetti A, Pozzilli C
Mult Scler (ISSN: 1352-4585, 1477-0970, 1352-4585linking), 2012 Oct; 18: 197-197.
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* F-18 FDG PET/CT metabolic tumor volume correlates with epidermal grow factor receptor expression in patients with NSCLC (59 visite)
Nappi A, Giacomobono S, Improta G, Nardelli A, Gallicchio R, Soscia E, Leggiadro F, Zupa A, Giudice G, Capacchione D, Vita G, Lequaglie C, Storto G
Eur J Nucl Med Mol Imaging (ISSN: 1619-7070, 1619-7089, 0340-6997), 2012 Oct; 39: N/D-N/D.
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* Correlation between EGFr expression and accelerated proliferation during radiotherapy of head and neck squamous cell carcinoma (70 visite)
Pedicini P, Nappi A, Strigari L, Jereczek-Fossa BA, Alterio D, Cremonesi M, Botta F, Vischioni B, Caivano R, Fiorentino A, Improta G, Storto G, Benassi M, Orecchia R, Salvatore M
Radiation Oncology (ISSN: 1748-717x), 2012 Sep 24; 7: 143-143.
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* Modelling the correlation between EGFr expression and tumour cell radiosensitivity, and combined treatments of radiation and monoclonal antibody EGFr inhibitors (80 visite)
Pedicini P, Caivano R, Jereczek-Fossa BA, Strigari L, Vischioni B, Alterio D, Cremonesi M, Botta F, Nappi A, Improta G, Storto G, Benassi M, Orecchia R
Theor Biol Med Model (ISSN: 1742-4682), 2012 Jun 19; 9(1): 23-23.
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* Native expression and purification of hormone-sensitive lipase from Psychrobacter sp. TA144 enhances protein stability and activity (108 visite)
Ascione G, de Pascale D, De Santi C, Pedone C, Dathan NA, Monti SM
Biochem Biophys Res Commun (ISSN: 1090-2104, 0006-291x, 1090-2104electronic), 2012 Apr 13; 420(3): 542-546.
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* Multiple sclerosis: cerebral circulation time (80 visite)
Mancini M, Morra VB, Di Donato O, Maglio V, Lanzillo R, Liuzzi R, Salvatore E, Brunetti A, Iaccarino V, Salvatore M
Radiology (ISSN: 1527-1315, 0033-8419), 2012 Mar; 262(3): 947-955.
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* A randomized controlled clinical trial of growth hormone in amyotrophic lateral sclerosis: clinical, neuroimaging, and hormonal results (90 visite)
Saccà F, Quarantelli M, Rinaldi C, Tucci T, Piro R, Perrotta G, Carotenuto B, Marsili A, Palma V, De Michele G, Brunetti A, Brescia Morra V, Filla A, Salvatore M
J Neurol (ISSN: 1432-1459, 0340-5354, 1432-1459electronic), 2012 Jan; 259(1): 132-138.
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* Contrast-Enhanced Ultrasound Evaluation Of The Cerebral Circulation Time In Patients With Multiple Sclerosis (64 visite)
Mancini M, Brescia Morra V, Di Donato O, Maglio V, Lanzillo R, Liuzzi R, Brunetti A, Salvatore M
J Ultrasound Med, 2012; N/D: 49-49.
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* Italian multicenter study on venous hemodynamics in multiple sclerosis: Advanced Sonological Protocol (76 visite)
Malferrari G, Del Sette M, Zedde M, Sanguigni S, Carraro C, Baracchini C, Mancini M, Stolz E
Perspect Med (ISSN: 2211-968x), 2012; 1-12: 399-403.
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* Insulin-like growth factor (IGF)-I and IGF-binding protein-3 serum levels in relapsing-remitting and secondary progressive multiple sclerosis patients (90 visite)
Lanzillo R, Di Somma C, Quarantelli M, Ventrella G, Gasperi M, Prinster A, Vacca G, Pivonello C, Orefice G, Colao A, Morra VB
Eur J Neurol (ISSN: 1351-5101, 1468-1331electronic), 2011 Dec; 18(12): 1402-1406.
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* Chronic cerebrospinal venous insufficiency in multiple sclerosis: clinical correlates from a multicentre study (68 visite)
Bastianello S, Romani A, Viselner G, Tibaldi EC, Giugni E, Altieri M, Cecconi P, Mendozzi L, Farina M, Mariani D, Galassi A, Quattrini C, Mancini M, Brescia VM, Lagace A, Mcdonald S, Bono G, Bergamaschi R
Bmc Neurol (ISSN: 1471-2377), 2011 Oct 26; 11: 132-132.
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* Changes In Magnetic Resonance Imaging Disease Measures Over 3 Years In Mildly Disabled Patients With Relapsing-Remitting Multiple Sclerosis Receiving Interferon Beta-1a In The Cognitive Impairment In Multiple Sclerosis (cogimus) Study (66 visite) (PDF 87 visite)
Bastianello S, Giugni E, Amato MP, Tola MR, Trojano M, Galletti S, Luccichenti G, Quarantelli M, Picconi O, Patti F, COGIMUS
Bmc Neurol (ISSN: 1471-2377), 2011 Oct 14; 11: 125-125.
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* HMGA proteins promote ATM expression and enhance cancer cell resistance to genotoxic agents (81 visite)
Palmieri D, Valentino T, D'Angelo D, De Martino I, Postiglione I, Pacelli R, Croce CM, Fedele M, Fusco A
Oncogene (ISSN: 0950-9232, 1476-5594), 2011 Jul 7; 30(27): 3024-3035.
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* Molecular imaging of atherosclerosis in translational medicine (152 visite)
Perrone-filardi P, Dellegrottaglie S, Rudd JH, Costanzo P, Marciano C, Vassallo E, Marsico F, Ruggiero D, Petretta MP, Chiariello M, Cuocolo A
Eur J Nucl Med Mol Imaging (ISSN: 1619-7089, 1619-7070, 0340-6997), 2011 May; 38(5): 969-975.
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* Predictive factors of neutralizing antibodies development in relapsing-remitting multiple sclerosis patients on interferon Beta-1b therapy (67 visite) (PDF 82 visite)
Lanzillo R, Orefice G, Prinster A, Ventrella G, Liuzzi R, Scarano V, Florio C, Vacca G, Brunetti A, Alfano B, Brescia Morra V, Bonavita V
Neurol Sci (ISSN: 1590-1874, 1590-3478), 2011 Apr; 32(2): 287-292.
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* BDNF Val66Met polymorphism and brain volumes in multiple sclerosis (150 visite) (PDF 104 visite)
Dinacci D, Tessitore A, Russo AA, De Bonis ML, Lavorgna L, Picconi O, Sacco R, Bonavita S, Gallo A, Servillo G, Marcuccio L, Comerci M, Galletti P, Alfano B, Tedeschi G
Neurol Sci (ISSN: 1590-1874, 1590-3478, 1590-1874linking), 2011 Feb; 32(1): 117-123.
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* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a major fragment of the resuscitation-promoting factor RpfB from Mycobacterium tuberculosis (75 visite)
Ruggiero A, Squeglia F, Pirone L, Correale S, Berisio R
Communicationsacta Crystallographica Section F Structural Biology And Crystallization (ISSN: 1744-3091, 1744-4309), 2011 Jan 1; 67(1): 164-168.
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* Gene cloning and protein expression of γ-glutamyltranspeptidases from Thermus thermophilus and Deinococcus radiodurans: Comparison of molecular and structural properties with mesophilic counterparts (66 visite)
Castellano I, Di Salle A, Merlino A, Rossi M, La Cara F
Extremophilesextremophiles (ISSN: 1431-0651, 1433-4909), 2011; 15(2): 259-270.
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* Growth Hormone Axis In Early Multiple Sclerosis Patients Before And After 2 Years Treatment With Interferon Beta-1b - An Interim Analysis (50 visite)
Lanzillo R, Di Somma C, Quarantelli M, Ventrella G, Vacca G, Liuzzi R, Amato L, Orefice G, Colao A, Brescia Morra V
Proceedings Of The Xlii Meeting Of The Italian Society Of Neurology, 2011; nd: 360-360.
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* Modulation of PARP-1 and PARP-2 expression by L-carnosine and trehalose after LPS and INFγ-induced oxidative stress (83 visite)
Spina-Purrello V, Giliberto S, Barresi V, Nicoletti VG, Giuffrida Stella AM, Rizzarelli E
Neurochemical Research (ISSN: 0364-3190, 1573-6903), 2010 Dec; 35(12): 2144-2153.
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* Expression, purification, crystallization and preliminary x-ray crystallographic analysis of the peptidoglycan binding region of the ser/thr kinase PrkC from staphylococcus aureus (72 visite)
Ruggiero A, Squeglia F, Izzo V, Silipo A, Vitagliano L, Molinaro A, Berisio R
Protein And Peptide Letters (ISSN: 0929-8665, 1875-5305), 2010 Oct; 17(10): 1296-1299.
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* Atorvastatin combined to interferon to verify the efficacy (ACTIVE) in relapsing-remitting active multiple sclerosis patients: A longitudinal controlled trial of combination therapy (79 visite)
Lanzillo R, Orefice G, Quarantelli M, Rinaldi C, Prinster A, Ventrella G, Spitaleri D, Lus G, Vacca G, Carotenuto B, Salvatore E, Brunetti A, Tedeschi G, Brescia Morra V
Mult Scler (ISSN: 1352-4585, 1477-0970, 1352-4585linking), 2010 Apr; 16(4): 450-454.
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* A voxel-based morphometry study of disease severity correlates in relapsing- remitting multiple sclerosis (110 visite) (PDF 82 visite)
Prinster A, Quarantelli M, Lanzillo R, Orefice G, Vacca G, Carotenuto B, Alfano B, Brunetti A, Brescia Morra V, Salvatore M
Mult Scler (ISSN: 1352-4585, 1477-0970, 1352-4585linking), 2010 Jan; 16(1): 45-54.
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* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of the resuscitation promoting factor interacting protein RipA from M. tuberculosis (67 visite)
Ruggiero A, Squeglia F, Esposito C, Marasco D, Pedone E, Pedone C, Berisio R
Protein And Peptide Letters (ISSN: 0929-8665, 1875-5305), 2010 Jan; 17(1): 70-73.
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* Intracardiac injection of AdGRK5-NT reduces left ventricular hypertrophy by inhibiting NF-κB-Dependent hypertrophic gene expression (66 visite)
Sorriento D, Santulli G, Fusco A, Anastasio A, Trimarco B, Iaccarino G
Hypertensionhypertension (ISSN: 0194-911x), 2010; 56(4): 696-704.
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* Myocardial expression of FOXO3a-Atrogin-1 pathway in human heart failure (62 visite)
Galasso G, De Rosa R, Piscione F, Iaccarino G, Vosa C, Sorriento D, Piccolo R, Rapacciuolo A, Walsh K, Chiariello M
Eur J Heart Fail European Journal Of Heart Failure (ISSN: 1388-9842), 2010; 12(12): 1290-1296.
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* VEGFR1(D2) in drug discovery: Expression and molecular characterization (77 visite)
Di Stasi R, Diana D, Capasso D, Palumbo R, Romanelli A, Pedone C, Fattorusso R, D'Andrea LD
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2010; 94(6): 800-809.
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* Imaging of alpha(v)beta(3) expression by a bifunctional chimeric RGD peptide not cross-reacting with alpha(v)beta(5) (86 visite)
Zannetti A, Del Vecchio S, Iommelli F, Del Gatto A,  De Luca S, Zaccaro L, Papaccioli A, Sommella J, Panico M, Speranza A, Grieco P, Novellino E, Saviano M, Pedone C, Salvatore M
Clin Cancer Res (ISSN: 1078-0432, 1078-0432linking), 2009 Sep 15; 15(16): 5224-5233.
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* Imaging of αvβ3 expression by a bifunctional chimeric RGD peptide not cross-reacting with α vβ5 (96 visite)
Zannetti A, Del Vecchio S, Iommelli F, Del Gatto A, De Luca S, Zaccaro L, Papaccioli A, Sommella J, Panico M, Speranza A, Grieco P, Novellino E, Saviano M, Pedone C, Salvatore M
Clin Cancer Res (ISSN: 1078-0432, 1078-0432linking), 2009 Sep 15; 15(16): 5224-5233.
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* Serum levels of insulin like growth factor-1 and insulin like growth factor binding protein-3 in relapsing and secondary progressive multiple sclerosis (98 visite)
Lanzillo R, Di Somma C, Quarantelli M, Gasperi M, Ventrella G, Prinster A, Vacca G, Orefice G, Colao A, Morra VB
Mult Scler (ISSN: 1352-4585, 1477-0970, 1352-4585linking), 2009 Sep; 15(9): 1402-1406.
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* Regulated BMP-4 Expression for Bone Regeneration by Thymidine Kinase and Ganciclovir Treatments (62 visite)
Lombardo B, Rocco T, Esposito MT, Cantilena B, Gargiulo S, Brunetti A, Montanaro D, Troncone G, Salvatore F, Pastore L
Molecular Therapy (ISSN: 1525-0016, 1525-0024), 2009 May; 17: N/D-N/D.
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* A Double-Blind, Placebo-Controlled, Randomized Trial of Growth Hormone as Add-On Therapy to Riluzole in Patients with Amyotrophic Lateral Sclerosis: Preliminary MRS, Hormonal, and Population Analysis (84 visite)
Sacca F, Quarantelli M, Rinaldi C, Tucci T, Piro R, Carotenuto B, Marsili A, Palma V, Bresciamorra V, Brunetti A, De Michele G, Filla A, Salvatore M
Neurology (ISSN: 0028-3878, 1526-632x), 2009 Mar 17; 72(11): N/D-N/D.
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* A Randomized Trial of Growth Hormone as Add. On Therapy to Riluzole in Patients with Amyotrophic Lateral Sclerosis (65 visite)
Sacca F, Quarantelli M, Rinaldi C, Tucci T, Piro R, Carotenuto B, Marsili A, Palma V, Bresciamorra V, Brunetti A, De Michele G, Filla A, Salvatore M
Neurology (ISSN: 0028-3878, 1526-632x), 2009 Mar 17; 76(9): N/D-N/D.
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* BDNF V4166Met Polymorphism and Brain Volumes in Multiple Sclerosis: A Relationship Still Debated (119 visite)
Dinacci D, Russo AA, Tessitore A, De Bonis ML, Lavorgna L, Picconi O, Sacco R, Bonavita S, Gallo A, Servillo G, Comerci M, Galletti P, Alfano B, Tedeschi G
Neurology (ISSN: 0028-3878, 1526-632x), 2009 Mar 17; 72(11): N/D-N/D.
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* Relationship between Clinical Aspects in Early Phases of Relapsing-Remitting Multiple Sclerosis and Subsequent Brain Volume Changes (73 visite)
Quarantelli M, Lanzillo R, Prinster A, Mollica C, Orefice G, Brunetti A, Vacca G, Salvatore M, Morra VB
Neurology (ISSN: 0028-3878, 1526-632x), 2009 Mar 17; 72(11): N/D-N/D.
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* Brain atrophy evolution and lesion load accrual in multiple sclerosis: A 2-year follow-up study (161 visite) (PDF 126 visite)
Tedeschi G, Dinacci D, Comerci M, Lavorgna L, Savettieri G, Quattrone A, Livrea P, Patti F, Morra VB, Servillo G, Orefice G, Paciello M, Prinster A, Coniglio G, Bonavita S, Di Costanzo A, Bellacosa A, Valentino P, Quarantelli M, Brunetti A, Salemi G, D'Amelio M, Simone I, Salvatore M, Bonavita V, Alfano B
Mult Scler (ISSN: 1352-4585, 1477-0970, 1352-4585linking), 2009 Feb; 15(2): 204-211.
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* Elevated Expression of the Tyrosine Phosphatase SHP-1 Defines a Subset of High-Grade Breast Tumors (79 visite)
Insabato L, Amelio I, Quarto M, Zannetti A, Tolino F, De Mauro G, Cerchia L, Riccio P, Baumhoer D, Condorelli G, Terracciano L, De Franciscis V
Oncology (ISSN: 0030-2414), 2009; 77(6): 378-384.
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* Correlation of disease severity and regional brain tissue loss in relapsing-remitting multiple sclerosis: a voxel-based morphometry study in a large population (112 visite) (PDF 82 visite)
Morra VB, Prinster A, Lanzillo R, Quarantelli M, Vacca G, Mollica C, Schiavone V, Brunetti A, Salvatore E, Alfano B, Orefice G
Mult Scler (ISSN: 1352-4585, 1477-0970, 1352-4585linking), 2008 Sep; 14: 45-54.
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* Combined Mri And Pet-18fdg Study In Patients With Primary Progressive (pp) And Relapsing Remitting (rr) Multiple Sclerosis (ms) (148 visite)
Vicidomini C, Comerci M, Salvatore E, Quarantelli M, Varrone A, Evangelista L, Prinster A, Morra VB, Brunetti A, Salvatore M,  Alfano B, Pappata S
Abstract Book Of Dimi/Emil Annual Meeting 2008, 2008 Jun 1; N/D: N/D-N/D.
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* An open-label randomised clinical trial of atorvastatin in combination with IFN Beta 1a in active multiple sclerosis patients: preliminary results (57 visite)
Orefice G, Quarantelli M, Lanzillo R, Brunetti A, Salvatore P, Prinster A, Vacca G, Mollica C, Bonavita V, Morra VB, Prinster A
J Neurol (ISSN: 0340-5354, 1432-1459, 1432-1459electronic), 2008 Jun; 255: N/D-N/D.
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* Expression and purification of the D4 region of PLD1 and characterization of its interaction with PED-PEA15 (67 visite)
Viparelli F, Doti N, Sandomenico A, Marasco D, Dathan NA, Miele C, Beguinot F, Monti SM, Ruvo M
Protein Expr Purif (ISSN: 1046-5928), 2008 Jun; 59(2): 302-308.
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* Correlation between fatigue and brain atrophy and lesion load in multiple sclerosis patients independent of disability (140 visite) (PDF 102 visite)
Tedeschi G, Dinacci D, Lavorgna L, Prinster A, Savettieri G, Quattrone A, Livrea P, Messina C, Reggio A, Servillo G, Bresciamorra V, Orefice G, Paciello M, Brunetti A, Paolillo A, Coniglio G, Bonavita S, Di Costanzo A, Bellacosa A, Valentino P, Quarantelli M, Patti F, Salemi G, Cammarata E, Simone I, Salvatore M, Bonavita V, Alfano B
J Neurol Sci (ISSN: 0022-510x), 2007 Dec 15; 263(1-2): 15-19.
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* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a resuscitation-promoting factor from Mycobacterium tuberculosis (57 visite)
Ruggiero A, Tizzano B, Geerlof A, Pedone E, Pedone C, Wilmanns M, Berisio R
Communicationsacta Crystallographica Section F Structural Biology And Crystallization (ISSN: 1744-3091, 1744-4309), 2007 Oct 1; 63(10): 870-873.
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* In vivo imaging of alpha(v) beta(3) integrin expression with a radiolabeled chimeric RGD peptide (80 visite)
Del Vecchio S, Zannetti A, Panico M, Speranza A, Iommelli F, Papaccioli A, Sommella J, Lettieri A, Saviano M, Zaccaro L, Del Gatto A, Lang L, Pedone C, Salvatore M
Eur J Nucl Med Mol Imaging (ISSN: 1619-7070, 1619-7089, 0340-6997), 2007 Oct; 34: N/D-N/D.
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* An ontology approach for classification of abnormal white matter in patients with Multiple Sclerosis (141 visite) (PDF 124 visite)
Alfano B, Brunetti A, De Pietro G, Esposito A
Lecture Notes In Computer Science (ISSN: 0302-9743, 0302-974335404636319783540463634, 0302-974335402975459783540297543), 2007; 4799LNCS: 389-402.
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* Increased CD154 expression in uninfected infants born to HIV-positive mothers exposed to antiretroviral prophylaxis (50 visite)
Romano MF, Buffolano W, Bisogni R, Russo R, Liuzzi R, Newell ML, Carandente P
Viral Immunol (ISSN: 0882-8245), 2006 Jun; 19(3): 363-372.
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* Grey matter loss in relapsing-remitting multiple sclerosis: A voxel-based morphometry study (79 visite) (PDF 105 visite)
Prinster A, Quarantelli M, Orefice G, Lanzillo R, Brunetti A, Mollica C, Salvatore E, Morra VB, Coppola G, Vacca G, Alfano B, Salvatore M
Neuroimage (ISSN: 1053-8119, 1053-8119linking), 2006 Feb 1; 29(3): 859-867.
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* Inhibition of Sp1 activity by a decoy PNA-DNA chimera prevents urokinase receptor expression and migration of breast cancer cells (85 visite)
Zannetti A, Del Vecchio S, Romanelli A, Scala S, Saviano M, Cali' G, Stoppelli MP, Pedone C, Salvatore M
Biochem Pharmacol Biochemical Pharmacology (ISSN: 0006-2952, 1873-2968), 2005 Nov 1; 70(9): 1277-1287.
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* Characterization of a novel RGD-containing peptide with improved selectivity for imaging alpha v beta 3 integrin expression (89 visite)
Del Vecchio S, Zannetti A, Del Gatto A, Grieco P, Iommelli F, Zaccaro L, Panico M, Saviano M, Blystone SD, Pedone C, Salvatore M
Eur J Nucl Med Mol Imaging (ISSN: 1619-7070, 1619-7089, 0340-6997), 2005 Sep; 32: N/D-N/D.
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* Does a gender-related effect of growth hormone (GH) replacement exist on cardiovascular risk factors, cardiac morphology, and performance and atherosclerosis? Results of a two-year open, prospective study in young adult men and women with severe GH deficiency (69 visite)
Colao A, Di Somma C, Cuocolo A, Spinelli L, Acampa W, Spiezia S, Rota F, Savanelli MC, Lombardi G
J Clin Endocrinol Metab (ISSN: 0021-972x), 2005 Sep; 90(9): 5146-5155.
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* Brain atrophy and lesion load in a large population of patients with multiple sclerosis (144 visite) (PDF 128 visite)
Tedeschi G, Lavorgna L, Russo P, Prinster A, Dinacci D, Savettieri G, Quattrone A, Livrea P, Messina C, Reggio A, Bresciamorra V, Orefice G, Paciello M, Brunetti A, Coniglio G, Bonavita S, Di Costanzo A, Bellacosa A, Valentino P, Quarantelli M, Patti F, Salemi G, Cammarata E, Simone IL, Salvatore M, Bonavita V, Alfano B
Neurology (ISSN: 0028-3878, 1526-632x), 2005 Jul 26; 65(2): 280-285.
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* Expression, purification and partial characterization of the Krüppel-associated box (KRAB) from the human ZNF2 protein (66 visite)
Rivieccio V, Mannini R, Concilio L, D'Auria S, Pedone C, Grimaldi G
Protein And Peptide Letters (ISSN: 0929-8665, 1875-5305), 2005; 12(6): 527-532.
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* Ischemic neoangiogenesis enhanced by β2-adrenergic receptor overexpression: A novel role for the endothelial adrenergic system (82 visite)
Iaccarino G, Ciccarelli M, Sorriento D, Galasso G, Campanile A, Santulli G, Cipolletta E, Cerullo V, Cimini V, Altobelli GG, Piscione F, Priante O, Pastore L, Chiariello M, Salvatore F, Koch WJ, Trimarco B
Circ Res (ISSN: 0009-7330, 1524-4571electronic), 2005; 97(11): 1182-1189.
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* Peptide nucleic acids (PNA)-DNA chimeras targeting transcription factors as a tool to modify gene expression (89 visite)
Borgatti M, Finotti A, Romanelli A, Saviano M, Bianchi N, Lampronti I, Lambertini E, Penolazzi L, Nastruzzi C, Mischiati C, Piva R, Pedone C, Gambari R
Curr Drug Targets (ISSN: 1389-4501), 2004 Nov; 5(8): 735-744.
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* Normal and abnormal brain tissue volumes and neuropsychological status in relapsing-remitting multiple sclerosis (71 visite)
Morra VB, Quarantelli M, Lanzillo R, Prinster A, Coppola G, Brunetti A, Salvatore E, Mollica C, Orefice R, Liuzzi R, Alfano B, Orefice G
Eur J Neurol (ISSN: 1351-5101, 1468-1331electronic, 1351-5101linking), 2004 Sep; 11: N/D-N/D.
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* Normal and abnormal brain tissue volumes and neuropsychological status in relapsing-remitting multiple sclerosis (68 visite)
Morra V, Quarantelli M, Lanzillo R, Prinster A, Coppola G, Brunetti A, Salvatore E, Mollica C, Orefice R, Liuzzi R, Alfano B, Orefice G
J Neurol (ISSN: 0340-5354, 1432-1459, 1432-1459electronic), 2004 Jun; 251: N/D-N/D.
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* Bcl-2 overexpression prevents 99mTc-MIBI uptake in breast cancer cell lines (80 visite)
Aloj L, Zannetti A, Caracó C, Del Vecchio S, Salvatore M
Eur J Nucl Med Mol Imaging (ISSN: 1619-7070, 1619-7089, 0340-6997), 2004; 31(4): 521-527.
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* High-level expression of Aliciclobacillus acidocaldarius thioredoxin in Pichia pastoris and Bacillus subtilis (58 visite)
Digilio Filomena A, Morra R, Pedone E, Bartolucci S, Rossi M
Protein Expr Purif (ISSN: 1046-5928), 2003 Sep; 30(2): 179-184.
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* Inhibition of early Tc-99m-MIBI uptake by Bcl-2 anti-apoptotic protein overexpression in untreated breast carcinoma (98 visite)
Del Vecchio S, Zannetti A, Aloj L, Caracò C, Ciarmiello A, Salvatore M
Eur J Nucl Med Mol Imaging (ISSN: 1619-7070, 1619-7089, 0340-6997), 2003 Jun; 30(6): 879-887.
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* Brain tissue volume changes in relapsing-remitting multiple sclerosis: Correlation with lesion load (151 visite) (PDF 100 visite)
Quarantelli M, Ciarmiello A, Morra VB, Orefice G, Larobina M, Lanzillo R, Schiavone V, Salvatore E, Alfano B, Brunetti A
Neuroimage (ISSN: 1053-8119, 1053-8119linking), 2003 Feb; 18(2): 360-366.
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* Cloning and Expression of a Novel Hepatitis B Virus-binding Protein from HepG2 Cells (96 visite)
De Falco S, Ruvoletto MG, Verdoliva A, Ruvo M, Raucci A, Marino M, Senatore S, Cassani G, Alberti A, Pontisso P, Fassina G
J Biol Chem Journal Of Biological Chemistry (ISSN: 0021-9258, 1083-351x), 2001 Sep 28; 276(39): 36613-36623.
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* 99mTc-MIBI uptake and Bcl-2 overexpression in untreated breast cancer patients (66 visite)
Del Vecchio S, Zannetti A, Ciarmiello A, Aloj L, Fonti R, Caraco C, Salvatore M
Eur J Nucl Med Mol Imaging (ISSN: 0340-6997, 1619-7070, 1619-7089), 2001 Sep; 28(8): N/D-N/D.
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Automated segmentation and measurement of global white matter lesion volume in patients with multiple sclerosis (167 visite) (PDF 407 visite)
Alfano B, Brunetti A, Larobina M, Quarantelli M, Tedeschi E, Ciarmiello A, Covelli EM, Salvatore M
Journal Of Magnetic Resonance Imaging (ISSN: 1053-1807), 2000 Dec; 12(6): 799-807.
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Coordinate up-regulation of Sp1 DNA-binding activity and urokinase receptor expression in breast carcinoma (83 visite)
Zannetti A, Del Vecchio S, Carriero MV, Fonti R, Franco P, Botti G, D'Aiuto G, Stoppelli MP, Salvatore M
Cancer Res (ISSN: 0008-5472, 1538-7445, 1538-7445electronic), 2000 Mar 15; 60(6): 1546-1551.
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Measurement of P-glycoprotein expression in human neuroblastoma xenografts using in vitro quantitative autoradiography (55 visite)
Fonti R, Levchenko A, Mehta BM, Zhang J, Tsuruo T, Larson SM
Nuclear Medicine And Biology (ISSN: 0969-8051, 0883-2897), 1999 Jan; 26(1): 35-41.
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Mucosal expression of carcinoembryonic antigen and carbohydrate antigen 19-9 in patients with gastritis and gastric cancer (62 visite)
Esposito G, Tempesta A, Galati MG, De Bellis M, Rossi GB, Potena MI, Marone P, Daniele B, Del Vecchio S
(ISSN: 0361-090x), 1999; 23(2): 116-122.
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Automated lesion identification and volumetric measurement of lesion load in multiple sclerosis using a multispectral relaxometric MR approach (61 visite)
Alfano B, Brunetti A, Ciarmiello A, Covelli E, Larobina M, Salvatore M
Radiology (ISSN: 0033-8419, 1527-1315), 1997 Nov; 205: N/D-N/D.
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Retinoic acid receptors α, β and γ, and cellular retinol binding protein-I expression in breast fibrocystic disease and cancer (72 visite)
Pasquali D, Bellastella A, Valente A, Botti G, Capasso I, del Vecchio S, Salvatore M, Colantuoni V, Sinisi AA
Eur J Endocrinol (ISSN: 0804-4643), 1997 Oct; 137(4): 410-414.
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Fractional retention of technetium-99m-sestamibi as an index of P- glycoprotein expression in untreated breast cancer patients (63 visite)
Del Vecchio S, Ciarmiello A, Pace L, Potena MI, Carriero MV, Mainolfi C, Thomas R, D'Aiuto G, Tsuruo T, Salvatore M
Journal Of Nuclear Medicine (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1997 Sep; 38(9): 1348-1351.
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White matter lesion detection in multiple sclerosis: Improved interobserver concordance with multispectral MRI display (115 visite) (PDF 95 visite)
Brunetti A, Tedeschi G, Di Costanzo A, Covelli EM, Aloj L, Bonavita S, Ciarmiello A, Alfano B, Salvatore M
J Neurol (ISSN: 0340-5354, 1432-1459, 1432-1459electronic), 1997 Sep; 244(9): 586-590.
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Measurement of P-glycoprotein expression in multidrug-resistant human neuroblastoma cell lines using self-competitive binding assay (81 visite)
Levchenko A, Mehta B, Spengler BA, Narkar A, Fonti R, Biedler JL, Tsuruo T, Larson SM
Anal Biochem (ISSN: 0003-2697), 1996 May 1; 236(2): 338-343.
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Tc-99m-SESTAMIBI efflux and P-glycoprotein expression in human breast carcinoma (57 visite)
Ciarmiello A, Del Vecchio S, Potena MI, Mainolfi C, Carriero MV, Tsuruo T, Marone A, Salvatore M
Journal Of Nuclear Medicine (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1995; 36(5SUPPL.): N/D-N/D.
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Multiparametric characterization of lesions of the white matter in multiple sclerosis patients (59 visite)
BRUNETTI A, TEDESCHI G, ALFANO B, DICOSTANZO A, ALOJ L, ARPAIA M, COVELLI E, BONAVITA S, SALVATORE M
Neuroradiology 1994, 1994; N/D: N/D-N/D.
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Effect of retinoic acid on osteocalcin gene expression in human osteoblasts (42 visite)
Oliva A, Della Ragione F, Fratta M, Marrone G, Palumbo R, Zappia V
Biochem Biophys Res Commun (ISSN: 0006-291xprint, 0006-291xlinking), 1993 Mar 31; 191(3): 908-914.
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Urokinase and urokinase receptor overexpression in breast carcinoma as compared to benign lesions (58 visite)
Del Vecchio S, Stoppelli P, Fonti R, Carriero MV, Li P, Salvatore M
Meetingproceedings Of The American Association For Cancer Research Annual (ISSN: 0197-016x), 1993; 34(0): N/D-N/D.
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Ultrasonographic Evaluation Of Carotid Wall Thickness And Atherosclerosis In Essential Hypertension (52 visite)
Ferrara LA, Mancini M, Iannuzzi R, Marotta T
Fifth European Meeting On Hypertension European Society Of Hypertension Milan, 1991 Oct; N/D: 210-210.
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Relative protection from cerebral atherosclerosis of young patients with homozygous familial hypercholesterolemia (64 visite)
Postiglione A, Nappi A, Brunetti A, Soricelli A, Rubba P, Gnasso A, Cammisa M, Frusciante V, Cortese C, Salvatore M
Atherosclerosis (ISSN: 0021-9150, 1879-1484), 1991 Sep; 90(1): 23-30.
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Transient expression of glial-fibrillary acidic protein (GFAP) in the ependyma of the regenerating spinal cord in adult newts (52 visite)
Margotta V, Fonti R, Palladini G, Filoni S, Lauro GM
Journal Fur Hirnforschung (ISSN: 0021-8359), 1991; 32(4): 485-490.
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Quantitative assessment of blood-brain barrier permeability in multiple sclerosis using 68-Ga-EDTA and positron emission tomography (65 visite) (PDF 102 visite)
Pozzilli C, Bernardi S, Mansi L, Picozzi P, Iannotti F, Alfano B, Bozzao L, Lenzi GL, Salvatore M, Conforti P
J Neurol Neurosurg Psychiatry (ISSN: 0022-3050), 1988 Sep; 51(8): 1058-1062.
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130 Records (92 escludendo Abstract e Conferenze).
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Impact factor a 5 anni totale: 413.32 (296.088 escludendo Abstract e Conferenze).

Interrogazione bibliografica effettuata: (([btitle] "18f-Dpa-714" OR [btitle] "Sod1g93a" OR [btitle] "expression" OR [btitle] "amyotrophic" OR [btitle] "sclerosis") AND NOT [id] = 53109)







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