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The antineoplastic drug flavopiridol reverses memory impairment induced by Amyloid-ss1-42 oligomers in mice (106 visite)

Leggio GM, Catania MV, Puzzo D, Spatuzza M, Pellitteri R, Gulisano W, Torrisi SA, Giurdanella G, Piazza C, Impellizzeri AR, Gozzo L, Navarria A, Bucolo C, Nicoletti F, Palmeri A, Salomone S, Copani A, Caraci F, Drago F

Pharmacol Res (ISSN: 1096-1186electronic, 1043-6618linking), 2016 Apr; 106: 10-20.

Tipo di articolo: Journal Article,

Impact factor: 4.48

Impact factor a 5 anni: 4.497


Parole chiave: Alzheimer, S Disease, Cell Cycle, Flavopiridol, Flavopiridol (pubchem Cid: 9910986), Memory Deficit, Oligomers, Beta-Amyloid, β-Amyloid,

Url: https://www2.scopus.com/inward/record.uri?eid=2-s2.0-84958280806&partnerID=40&md5=f8641bd7b0cd2a98f09add524f2a1687

The ectopic re-activation of cell cycle in neurons is an early event in the pathogenesis of Alzheimer's disease (AD), which could lead to synaptic failure and ensuing cognitive deficits before frank neuronal death. Cytostatic drugs that act as cyclin-dependent kinase (CDK) inhibitors have been poorly investigated in animal models of AD. In the present study, we examined the effects of flavopiridol, an inhibitor of CDKs currently used as antineoplastic drug, against cell cycle reactivation and memory loss induced by intracerebroventricular injection of Aß1-42 oligomers in CD1 mice. Cycling neurons, scored as NeuN-positive cells expressing cyclin A, were found both in the frontal cortex and in the hippocampus of Aβ-injected mice, paralleling memory deficits. Starting from three days after Aβ injection, flavopiridol (0.5, 1 and 3 mg/kg) was intraperitoneally injected daily, for eleven days. Here we show that a treatment with flavopiridol (0.5 and 1 mg/kg) was able to rescue the loss of memory induced by Aβ1-42, and to prevent the occurrence of ectopic cell-cycle events in the mouse frontal cortex and hippocampus. This is the first evidence that a cytostatic drug can prevent cognitive deficits in a non-transgenic animal model of AD. © 2016 Elsevier Ltd. All rights reserved.
*** IBB - CNR ***

Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy., National Research Council, Institute of Neurological Sciences (ISN-CNR), Catania, Italy; IRCCS Associazione Oasi Maria S.S., Institute for Research on Mental Retardation and Brain Aging, Troina, EN, Italy., National Research Council, Institute of Neurological Sciences (ISN-CNR), Catania, Italy., Pharmacokinetic Unit, Unifarm Research Center, Catania, Italy., Department of Biomedical and Biotechnological Sciences, University of Catania, Catania, Italy; Pharmacokinetic Unit, Unifarm Research Center, Catania, Italy., IRCCS Neuromed, Pozzilli IS, Italy; Department of Physiology and Pharmacology, University of Rome Sapienza, Italy., National Research Council, Institute of Biostructure and Bioimaging (IBB-CNR), Catania, Italy; Department of Drug Sciences, University of Catania, Catania, Italy., IRCCS Associazione Oasi Maria S.S., Institute for Research on Mental Retardation and Brain Aging, Troina, EN, Italy; Department of Drug Sciences, University of Catania, Catania, Italy. Electronic address: carafil@hotmail.com.,
Hardy, J., The amyloid hypothesis for Alzheimer's disease: a critical reappraisal (2009) J. Neurochem., 110, pp. 1129-113

Giacobini, E., Gold, G., Alzheimer disease therapy-moving from amyloid-β to tau (2013) Nat. Rev. Neurol., 9, pp. 677-686

Walsh, D.M., Selkoe, D.J., A beta oligomers - a decade of discovery (2007) J. Neurochem., 101, pp. 1172-1184

Hynd, M.R., Scott, H.L., Dodd, P.R., Glutamate-mediated excitotoxicity and neurodegeneration in Alzheimer's disease (2004) Neurochem. Int., 45, pp. 583-595

Caricasole, A., Copani, A., Caraci, F., Aronica, E., Rozemuller, A.J., Caruso, A., Storto, M., Nicoletti, F., Induction of Dickkopf-1 a negative modulator of the Wnt pathway, is associated with neuronal degeneration in Alzheimer's brain (2004) J. Neurosci., 24, pp. 6021-6027

Herrup, K., Neve, R., Ackerman, S.L., Copani, A., Divide and die: cell cycle events as triggers of nerve cell death (2004) J. Neurosci., 24, pp. 9232-9239

Copani, A., Condorelli, F., Caruso, A., Vancheri, C., Sala, A., Giuffrida Stella, A.M., Canonico, P.L., Sortino, M.A., Mitotic signaling by beta-amyloid causes neuronal death (1999) FASEB J., 13, pp. 2225-2234

Copani, A., Hoozemans, J.J., Caraci, F., Calafiore, M., Van Haaster, E.S., Veerhius, R., Rozemuller, A.J.M., Nicoletti, F., DNA polymerase-ß is early expressed in neurons of Alzheimer's disease brain and is loaded into DNA replication forks ni neurons challenged with ß-amyloid (2006) J. Neurosci., 26, pp. 10949-10957

Arendt, T., Brückner, M.K., Linking cell-cycle dysfunction in Alzheimer's disease to a failure of synaptic plasticity (2010) Biochim. Biophys. Acta., 1772, pp. 413-421

Ueberham, U., Arendt, T., The expression of cell cycle proteins in neurons and its relevance for Alzheimer's disease (2005) Curr. Drug Targets CNS Neurol. Disord., 4, pp. 293-306

Wu, J., Stoica, B.A., Dinizo, M., Pajoohesh-Ganji, A., Piao, C., Faden, A.I., Delayed cell cycle pathway modulation facilitates recovery after spinal cord injury (2012) Cell Cycle, 11, pp. 1782-1795

Pallàs, M., Verdaguer, E., Jordà, E.G., Jiménez, A., Canudas, A.M., Camins, A., Flavopiridol: an antitumor drug with potential application in the treatment of neurodegenerative diseases (2005) Med. Hypotheses, 64 (2005), pp. 120-123

Osuga, H., Osuga, S., Wang, F., Fetni, R., Hogan, M.J., Slack, R.S., Hakim, A.M., Park, D.S., Cyclin-dependent kinases as a therapeutic target for stroke (2000) Proc. Natl. Acad. Sci. U. S. A., 97, pp. 10254-10259

Carlson, B.A., Dubay, M.M., Sausville, E.A., Worland, P.J., Flavopiridol induces G1 arrest with inhibition of cyclin-dependent kinase (cdk) 2 and cdk4 in human breast carcinoma cells (1996) Cancer Res., 56, pp. 2973-2978

Ledo, J.H., Azevedo, E.P., Clarke, J.R., Ribeiro, F.C., Figueiredo, C.P., Foguel, D., De Felice, F.G., Ferreira, S.T., Amyloid-β oligomers link depression-like behavior and cognitive deficits in mice (2001) Mol. Psychiatry, 18, pp. 1053-1054

Gong, Y., Klein, W.L., Alzheimer's disease-affected brain: presence of oligomeric Abeta ligands (ADDLs) suggests a molecular basis for reversible memory loss (2003) PNAS., 100, pp. 10417-10422

Maurice, T., Lockhart, B.P., Privat, A., Amnesia induced in mice by centrally administered beta-amyloid peptides involves cholinergic dysfunction (1996) Brain Res., 706, pp. 181-193

Micale, V., Cristino, L., Tamburella, A., Petrosino, S., Leggio, G.M., Di Marzo, V., Drago, F., Enhanced cognitive performance of dopamine D3 receptor knock-out mice in the step-through passive-avoidance test: assessing the role of the endocannabinoid/endovanilloid systems (2010) Pharmacol. Res., 61, pp. 531-536

Puzzo, D., Bizzoca, A., Loreto, C., Guida, C.A., Gulisano, W., Frasca, G., Bellomo, M., Palmeri, A., Role of F3/contactin expression profile in synaptic plasticity and memory in aged mice (2015) Neurobiol. Aging, 36, pp. 1702-1715

Varvel, N.H., Bhaskar, K., Patil, A.R., Pimplikar, S.W., Herrup, K., Lamb, B.T., Abeta oligomers induce neuronal cell cycle events in Alzheimer's disease (2008) J. Neurosci., 28, pp. 10786-10793

Caraci, F., Gulisano, W., Guida, A.C., Impellizzeri, A.R., Drago, F., Puzzo, D., Palmeri, A., A key role for TGF-β1 in hippocampal synaptic plasticity and memory (2015) Sci. Rep., 5, p. 11252

Zhou, L., Schmidt, K., Nelson, F.R., Zelesky, V., Troutman, M.D., Feng, B., The effect of breast cancer resistance protein and P-glycoprotein on the brain penetration of flavopiridol imatinib mesylate (Gleevec), prazosin, and 2-methoxy-3-(4-(2-(5-methyl-2-phenyloxazol-4-yl) ethoxy) phenyl) propanoic acid (PF-407288) in mice (2009) Drug. Metab. Dispos., 37, pp. 946-955

Kodaira, H., Kusuhara, H., Fujita, T., Ushiki, J., Fuse, E., Sugiyama, Y., Quantitative evaluation of the impact of active efflux by p-glycoprotein and breast cancer resistance protein at the blood-brain barrier on the predictability of the unbound concentrations of drugs in the brain using cerebrospinal fluid concentration as a surrogate (2011) J. Pharmacol. Exp. Ther., 339, pp. 935-944

Broadbent, N.J., Gaskin, S., Squire, L.R., Clark, R.E., Object recognition memory and the rodent hippocampus (2009) Learn. Mem., 17, pp. 5-11

Barker, G.R., Bird, F., Alexander, V., Warburton, E.C., Recognition memory for objects place, and temporal order: a disconnection analysis of the role of the medial prefrontal cortex and perirhinal cortex (2007) J. Neurosci., 27, pp. 2948-2957

De La Torre, A.V., Junyent, F., Folch, J., Pelegrí, C., Vilaplana, J., Auladell, C., Beas-Zarate, C., Camins, A., GSK3β inhibition is involved in the neuroprotective effects of cyclin-dependent kinase inhibitors in neurons (2012) Pharmacol. Res., 65, pp. 66-73

Tu, S., Okamoto, S., Lipton, S.A., Xu, H., Oligomeric Aβ-induced synaptic dysfunction in alzheimer's disease (2014) Mol. Neurodegener., 9, p. 48

Klein, W.L., Synaptotoxic amyloid-β oligomers: a molecular basis for the cause, diagnosis, and treatment of Alzheimer's disease (2013) J. Alzheimers Dis., 33 (S1), pp. S49-S65

Ferretti, M.T., Bruno, M.A., Ducatenzeiler, A., Klein, W.L., Cuello, A.C., Intracellular abeta-oligomers and early inflammation in a model of Alzheimer's disease (2012) Neurobiol. Aging, 33, pp. 1329-1342

Giuffrida, M.L., Caraci, F., Pignataro, B., Cataldo, S., De Bona, P., Bruno, V., Molinaro, G., Copani, A., Beta-amyloidmonomers are neuroprotective (2009) J. Neurosci., 29, pp. 10582-10587

Caraci, F., Pappalardo, G., Basile, L., Giuffrida, A., Copani, A., Tosto, R., Sinopoli, A., Guccione, S., Neuroprotective effects of the monoamine oxidase inhibitor tranylcypromine and its amide derivatives against Aβ(1-42)-induced toxicity (2015) Eur. J. Pharmacol., 764, pp. 256-263

Epelbaum, S., Youssef, I., Lacor, P.N., Chaurand, P., Duplus, E., Brugg, B., Duyckaerts, C., Delatour, B., Acute amnestic encephalopathy in amyloid-β oligomer-injected mice is due to their widespread diffusion in vivo (2015) Neurobiol. Aging, 36, pp. 2043-2052

Fluharty, B.R., Biasini, E., Stravalaci, M., Sclip, A., Diomede, L., Balducci, C., La Vitola, P., Harris, D.A., An N-terminal fragment of the prion protein binds to amyloid-β oligomers and inhibits their neurotoxicity in vivo (2013) J. Biol. Chem., 288, pp. 7857-7866

Balducci, C., Beeg, M., Stravalaci, M., Bastone, A., Sclip, A., Biasini, E., Tapella, L., Forloni, G., Synthetic amyloid-beta oligomers impair long-term memory independently of cellular prion protein (2010) Proc. Natl. Acad. Sci. U. S. A., 107, pp. 2295-2300

Youssef, I., Florent-Béchard, S., Malaplate-Armand, C., Koziel, V., Bihain, B., Olivier, J.-L., Leininger-Muller, B., Pillot, T., N-truncated amyloid-beta oligomers induce learning impairment and neuronal apoptosis (2008) Neurobiol. Aging, 29, pp. 1319-1333

McLean, C.A., Cherny, R.A., Fraser, F.W., Fuller, S.J., Smith, M.J., Beyreuther, K., Bush, A.I., Masters, C.L., Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease (1999) Ann. Neurol., 46, pp. 860-866

Webster, S.J., Bachstetter, A.D., Nelson, P.T., Schmitt, F.A., Van Eldik, L.J., Using mice to model Alzheimer's dementia: an overview of the clinical disease and the preclinical behavioral changes in 10 mouse models (2014) Front. Genet., 5, p. 88

Van DerPoel, A.M., Ethological study of the behaviour of the albino rat in a passive-avoidance test (1967) Acta Physiol. Pharmacol. Neerl., 14, pp. 503-505

Filali, M., Lalonde, R., Theriault, P., Julien, C., Calon, F., Planel, E., Cognitive and non-cognitive behaviors in the triple transgenic mouse model of Alzheimer's disease expressing mutated APP PS1, and Mapt (3xTg-AD) (2012) Behav. Brain Res., 234, pp. 334-342

Herrup, K., The contributions of unscheduled neuronal cell cycle events to the death of neurons in Alzheimer's disease (2012) Front. Biosci., 24, pp. 2101-2109

Yang, Y., Geldmacher, D.S., Herrup, K., DNA replication precedes neuronal cell death in Alzheimer's disease (2001) J. Neurosci., 21, pp. 2661-2668

Van Leeuwen, L.A., Hoozemans, J.J., Physiological and pathophysiological functions of cell cycle proteins in post-mitotic neurons: implications for Alzheimer's disease (2015) Acta Neuropathol., 129, pp. 511-525

Bhaskar, K., Maphis, N., Xu, G., Varvel, N.H., Kokiko-Cochran, O.N., Weick, J.P., Staugaitis, S.M., Lamb, B.T., Microglial derived tumor necrosis factor-α drives Alzheimer's disease-related neuronal cell cycle events (2014) Neurobiol. Dis., 62, pp. 273-285

Sivilia, S., Lorenzini, L., Giuliani, A., Gusciglio, M., Fernandez, M., Baldassarro, V.A., Mangano, C., Giardino, L., Multi-target action of the novel anti-Alzheimer compound CHF5074: in vivo study of long term treatment in Tg2576 mice (2013) BMC Neurosci., 14, p. 44

Yang, Y., Varvel, N.H., Lamb, B.T., Herrup, K., Ectopic cell cycle events link human Alzheimer's disease and amyloid precursor protein transgenic mouse models (2006) J. Neurosci., 26, pp. 775-784

Morris, D.G., Bramwell, V.H., Turcotte, R., Figueredo, A.T., Blackstein, M.E., Verma, S., Matthews, S., Eisenhauer, E.A., A phase II study of flavopiridol in patients with previously untreated advanced soft tissue sarcoma (2006) Sarcoma, 2006, p. 64374

Bose, P., Simmons, G.L., Grant, S., Cyclin-dependent kinase inhibitor therapy for hematologic malignancies (2013) Expert Opin. Investig. Drugs, 22, pp. 723-738

Sanphui, P., Pramanik, S.K., Chatterjee, N., Moorthi, P., Banerji, B., Biswas, S.C., Efficacy of cyclin dependent kinase 4 inhibitors as potent neuroprotective agents against insults relevant to Alzheimer's disease (2013) PLoS One, 8

Giovanni, A., Wirtz-Brugger, F., Keramaris, E., Slack, R., Park, D.S., Involvement of cell cycle elements cyclin-dependent kinases, pRb, and E2F x DP, in B-amyloid-induced neuronal death (1999) J. Biol. Chem., 274, pp. 19011-19016

Stinson, S.F., Hill, K., Siford, T.J., Phillips, L.R., Daw, T.W., Determination of flavopiridol (L86 8275

NSC 649890) in human plasma by reversed-phase liquid chromatography with electrochemical detection (1998) Cancer Chemother. Pharmacol., 42, pp. 261-265

Ganguli, M., Cancer and dementia: it's complicated (2015) Alzheimer Dis. Assoc. Disord., 29, pp. 177-182

Leclerc, S., Garnier, M., Hoessel, R., Marko, D., Bibb, J.A., Snyder, G.L., Greengard, P., Meijer, L., Indirubins inhibit glycogen synthase kinase-3 beta and CDK5/p25: two protein kinases involved in abnormal tau phosphorylation in Alzheimer's disease A property common to most cyclin-dependent kinase inhibitors? (2001) J. Biol. Chem., 276, pp. 251-260

Martinez, A., Perez, D.I., Gil, C., Lessons learnt from glycogen synthase kinase 3 inhibitors development for Alzheimer's disease (2013) Curr. Top. Med. Chem., 13, pp. 1808-1819

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De Rosa A, Pappata S, Pellegrino T, De Leva MF, Maddaluno G, Fiumara G, Carotenuto R, Petretta M, Filla A, De Michele G, Cuocolo A
* Reduced Cardiac 123i-Metaiodobenzylguanidine Uptake In Patients With Spinocerebellar Ataxia Type 2: A Comparative Study With Parkinson'S Disease (93 visite)
Eur J Nucl Med (ISSN: 1619-7089, 1619-7070, 0340-6997), 2013 Dec; 40(12): 1914-1921.
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Salvatore E, Quarantelli M, Russo C, Giorgio SM, Cervo A, Cocozza S, Di Maio L, Brunetti A, Filla A, De Michele G
* Default-Mode Network Alterations In Huntington'S Disease (100 visite)
Second Joint Limpe / Dismov Sin Meeting Rome, 2013 Nov; N/D: N/D-N/D.
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Quarantelli M, Salvatore E, Giorgio SM, Filla A, Cervo A, Russo CV, Cocozza S, Massarelli M, Brunetti A, De Michele G
* Default-mode network changes in Huntington's disease: an integrated MRI study of functional connectivity and morphometry (112 visite)
Plos One (ISSN: 1932-6203, 1932-6203electronic), 2013 Sep 19; 8(8): e72159-e72159.
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Erro R, Barone P, Vicidomini C, Picillo M, Pappata S
* Patients with Parkinson's disease and scans with (predominant) ipsilateral dopaminergic deficit (97 visite)
J Neurol (ISSN: 0340-5354, 1432-1459, 1432-1459electronic), 2013 Sep; 260(9): 2405-2406.
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McNeill A, Wu RM, Tzen KY, Aguiar PC, Arbelo JM, Barone P, Bhatia K, Barsottini O, Bonifati V, Bostantjopoulou S, Bressan R, Cossu G, Cortelli P, Felicio A, Ferraz HB, Herrera J, Houlden H, Hoexter M, Isla C, Lees A, Lorenzo-Betancor O, Mencacci NE, Pastor P, Pappata S, Pellecchia MT, Silveria-Moriyama L, Varrone A, Foltynie T, Schapira AH
* Dopaminergic Neuronal Imaging in Genetic Parkinson's Disease: Insights into Pathogenesis (127 visite)
Plos One (ISSN: 1932-6203, 1932-6203electronic), 2013 Jul 23; 8(7): e69190-e69190.
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Mariconda M, Soscia E, Sirignano C, Smeraglia F, Soldati A, Balato G
* Long-Term Clinical Results And Mri Changes After Tendon Ball Arthroplasty For Advanced Kienbock'S Disease (112 visite)
J Hand Surg Eur Vol (ISSN: 2043-6289, 0266-7681, 2043-6289electronic), 2013 Jun; 38(5): 508-514.
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Castiglione F, Mainenti PP, De Palma GD, Testa A, Bucci L, Pesce G, Camera L, Diaferia M, Rea M, Caporaso N, Salvatore M, Rispo A
* Noninvasive diagnosis of small bowel crohn's disease: Direct comparison of bowel sonography and magnetic resonance enterography (119 visite)
Inflamm Bowel Dis (ISSN: 1078-0998, 1536-4844electronic, 1078-0998linking), 2013 Apr; 19(4): 991-998.
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Giuffrida ML, Tomasello F, Caraci F, Chiechio S, Nicoletti F, Copani A
* Beta-Amyloid monomer and insulin/IGF-1 signaling in Alzheimer's disease (139 visite)
Mol Neurobiol (ISSN: 0893-7648), 2012 Dec; 46(3): 605-613.
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Forestier A, Douki T, Sauvaigo S, De Rosa V, Demeilliers C, Rachidi W
* Alzheimer's disease-associated neurotoxic peptide amyloid-beta impairs base excision repair in human neuroblastoma cells (111 visite)
Int J Mol Sc (ISSN: 1422-0067linking, 1422-0067electronic, 1661-6596), 2012 Nov 13; 13(11): 14766-14787.
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Erro R, Pappata S, Amboni M, Vicidomini C, Longo K, Santangelo G, Picillo M, Vitale C, Moccia M, Giordano F, Brunetti A, Pellecchia MT, Salvatore M, Barone P
* Anxiety is associated with striatal dopamine transporter availability in newly diagnosed untreated Parkinson's disease patients (132 visite)
Parkinsonism Relat Disord (ISSN: 1873-5126, 1353-8020, 1873-5126electronic), 2012 Nov; 18(9): 1034-1038.
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Pascual B, Prieto E, Arbizu J, Marti-climent JM, Peñuelas I, Quincoces G, Zarauza R, Pappata S, Masdeu JC
* Decreased carbon-11-flumazenil binding in early Alzheimer's disease (120 visite) (PDF 130 visite)
(ISSN: 0006-8950, 1460-2156electronic, 0006-8950linking), 2012 Sep; 135(9): 2817-2825.
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Travaglia A, Pietropaolo A, La Mendola D, Nicoletti VG, Rizzarelli E
* The inorganic perspectives of neurotrophins and Alzheimer's disease (177 visite)
J Chem Res (ISSN: 1873-3344, 0162-0134, 0162-0134print), 2012 Jun; 111: 130-137.
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Caraci F, Spampinato S, Sortino MA, Bosco P, Battaglia G, Bruno V, Drago F, Nicoletti F, Copani A
* Dysfunction of TGF-β1 signaling in Alzheimer's disease: Perspectives for neuroprotection (202 visite)
Cell Tissue Res (ISSN: 0302-766x), 2012 Jan; 347(1): 291-301.
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Pizzuti LM, Todaro P, Caleo A, Pace L, Vajro P
* Lymph node fine needle cytology in the diagnosis of infectious diseases and instrumental guides: Ultrasound and computed tomography (100 visite)
Infez Med (ISSN: 1124-9390), 2012; 20(SUPPL.3): 26-29.
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De Rosa A, Rinaldi C, Tucci T, Pappata S, Rossi F, Morra VB, Faggiano A, Colao A, De Michele G
* Co-existence of primary hyperparathyroidism and Parkinson's disease in three patients: An incidental finding? (129 visite)
Parkinsonism Relat Disord (ISSN: 1353-8020, 1873-5126, 1873-5126electronic), 2011 Dec; 17(10): 771-773.
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Esmaeilzadeh M, Farde L, Karlsson P, Varrone A, Halldin C, Waters S, Tedroff J
* Extrastriatal dopamine D 2 receptor binding in Huntington's disease (161 visite)
Hum Brain Mapp (ISSN: 1065-9471, 1097-0193electronic, 1065-9471linking), 2011 Oct; 32(10): 1626-1636.
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Damante CA, Ösz K, Nagy Z, Grasso G, Pappalardo G, Rizzarelli E, Sóvágó I
* Zn2+'s ability to alter the distribution of Cu2+ among the available binding sites of A beta(1-16)-polyethylenglycol-ylated peptide: Implications in Alzheimer's disease (108 visite)
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 2011 Jun 20; 50(12): 5342-5350.
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Caraci F, Molinaro G, Battaglia G, Giuffrida ML, Riozzi B, Traficante A, Bruno V, Cannella M, Merlo S, Wang X, Heinz BA, Nisenbaum ES, Britton TC, Drago F, Sortino MA, Copani A, Nicoletti F
* Targeting group II Metabotropic Glutamate (mGlu) receptors for the treatment of psychosis associated with alzheimer's disease: Selective activation of mGlu2 receptors amplifies β-amyloid toxicity in cultured neurons, whereas dual activation of mGlu2 and mGlu3 receptors is neuroprotective (250 visite)
Mol Pharmacol (ISSN: 0026-895x), 2011 Mar; 79(3): 618-626.
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Grasso G, Pietropaolo A, Spoto G, Pappalardo G, Tundo GR, Ciaccio C, Coletta M, Rizzarelli E
* Copper(I) and Copper(II) Inhibit A beta Peptides Proteolysis by Insulin-Degrading Enzyme Differently: Implications for Metallostasis Alteration in Alzheimer's Disease (152 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2011 Feb 25; 17(9): 2752-2762.
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Pappalardo G, Milardi D, Rizzarelli E, Sovago I
* The Inorganic Side of Alzheimer's Disease (110 visite)
Neurodegeneration (ISSN: 2041-3203), 2011; (7): N/D-N/D.
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Maurea S, Mollica C, Imbriaco M, Fusari M, Camera L, Salvatore M
* Magnetic resonance cholangiography with mangafodipir trisodium in Caroli's disease with pancreas involvement (109 visite)
Jop (ISSN: 1590-8577, 1590-0857), 2010 Sep 06; 11(5): 460-463.
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Lonardo E, Parish CL, Ponticelli S, Marasco D, Ribeiro D, Ruvo M, De Falco S, Arenas E, Minchiotti G
* A Small Synthetic Cripto Blocking Peptide Improves Neural Induction, Dopaminergic Differentiation, and Functional Integration of Mouse Embryonic Stem Cells in a Rat Model of Parkinson's Disease (118 visite)
Stem Cells (ISSN: 1066-5099), 2010 Sep; 28(8): 1326-1337.
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Cella L, Conson M, Liuzzi R, Caterino M, De Rosa N, Picardi M, Grimaldi F, Solla R, Farella A, Salvatore M, Pacelli R
* Radiation Induced Thyroid Disorders After Radiotherapy For Hodgkin S Disease: A Dosimetric Analysis (107 visite)
Radiotherapy And Oncology (ISSN: 0167-8140, 1879-0887, 1879-0887electronic), 2010; 96: N/D-N/D.
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Giuffrida ML, Caraci F, De Bona P, Pappalardo G, Nicoletti F, Rizzarelli E, Copani A
* The monomer state of beta-amyloid: where the Alzheimer's disease protein meets physiology (132 visite)
Rev Neurosci (ISSN: 0334-1763), 2010; 21(2): 83-93.
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De Rosa A, Criscuolo C, Mancini P, De Martino M, Giordano IA, Pappata S, Filla A, De Michele G
* Genetic screening for LRRK2 gene G2019S mutation in Parkinson's disease patients from Southern Italy (58 visite)
Parkinsonism Relat Disord (ISSN: 1353-8020print, 1353-8020linking, 1873-5126electronic), 2009 Mar; 15(3): 242-244.
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Spinelli L, Nicolai E, Acampa W, Imbriaco M, Pisani A, Rao MA, Scopacasa F, Cianciaruso B, De Luca N, Cuocolo A
* Cardiac performance during exercise in patients with Fabry's disease (101 visite)
European Journal Of Clinical Investigation (ISSN: 0014-2972, 1365-2362), 2008 Dec; 38(12): 910-917.
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De Bona P, Giuffrida ML, Attanasio F, Copani A, Pignataro B, Cataldo S, Rizzarelli E, Pappalardo G
* Designing trehalose-conjugated peptides for the inhibition of Alzheimer's A beta oligornerization and neurotoxicity (125 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2008 Sep; 14(8): N/D-N/D.
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Copani A, Guccione S, Giurato L, Caraci F, Calafiore M, Sortino MA
* The cell cycle molecules behind neurodegeneration in Alzheimer's disease: Perspectives for drug development (105 visite)
Curr Med Chem (ISSN: 0929-8673, 1875-533x, 1875-533xelectronic), 2008; 15(24): 2420-2432.
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Varrone A, Pagani M, Salvatore E, Salmaso D, Sansone V, Amboni M, Nobili F, De Michele G, Filla A, Barone P, Pappata S, Salvatore M
* Identification by [Tc-99]ECD SPECT of anterior cingulate hypoperfusion in progressive supranuclear palsy, in comparison with Parkinson's disease (156 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2007 Jul; 34(7): 1071-1081.
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Copani A, Caraci F, Hoozemans J, Calafiore M, Sortino M, Nicoletti F
* The nature of the cell cycle in neurons: Focus on a "non-canonical" pathway of DNA replication causally related to death (107 visite)
Biochim Biophys Acta (ISSN: 0925-4439, 0006-3002, 1570-9639), 2007 Apr; 1772(4): 409-412.
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Imbriaco M, Spinelli L, Cuocolo A, Maurea S, Sica G, Quarantelli M, Pisani A, Liuzzi R, Cianciaruso B, Sabbatini M, Salvatore M
* MRI characterization of myocardial tissue in patients with Fabry's disease (110 visite)
Ajr Am J Roentgenol (ISSN: 1546-3141, 0361-803x, 1546-3141electronic), 2007 Mar; 188(3): 850-853.
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Minopoli G, Stante M, Napolitano F, Telese F, Aloia L, De Felice M, Di Lauro R, Pacelli R, Brunetti A, Zambrano N, Russo T
* Essential roles for Fe65, Alzheimer amyloid precursor-binding protein, in the cellular response to DNA damage (101 visite)
J Biol Chem Journal Of Biological Chemistry (ISSN: 0021-9258, 1083-351x), 2007 Jan 12; 282(2): 831-835.
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Bosco P, Caraci F, Copani A, Spada R, Sortino M, Salluzzo R, Salemi M, Nicoletti F, Ferri R
* The CDC2 I-G-T haplotype associated with the APOE ε4 allele increases the risk of sporadic Alzheimer's disease in Sicily (112 visite)
Neurosci Lett (ISSN: 0304-3940), 2007; 419(3): 195-198.
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Copani A, Hoozemans JJM, Caraci F, Calafiore M, Van Haastert ES, Veerhuis R, Rozemuller AJM, Aronica E, Sortino MA, Nicoletti F
* Dna Polymerase-Beta Is Expressed Early In Neurons Of Alzheimer'S Disease Brain And Is Loaded Into Dna Replication Forks In Neurons Challenged With Beta-Amyloid (131 visite)
Journal Of Neuroscience (ISSN: 0270-6474, 0361-803x), 2006; 26(43): 10949-10957.
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Varrone A, Pagani M, Salmaso D, Salvatore E, Sansone V, Nobili F, Rodriguez G, Barone P, Larsson SA, De Michele G, Filla A, Pappata S, Salvatore M
* Anterior Cingulate Hypoperfusion Can Differentiate Progressive Supranuclear Palsy From Parkinson's Disease; Voxel-Based Analysis And CBA-Based PCA Analysis Of 99mTc-ECD SPECT Data (101 visite)
European Journal Of Nuclear Medicine And Molecular Imaging, 2005 Sep; 32: N/D-N/D.
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Rispo A, Imbriaco M, Celentano L, Cozzolino A, Camera L, Mainenti PP, Manguso F, Sabbatini F, D'Amico P, Castiglione F
* Noninvasive diagnosis of small bowel Crohn's disease: Combined use of bowel sonography and Tc-99m-HMPAO leukocyte scintigraphy (100 visite)
Inflamm Bowel Dis (ISSN: 1078-0998, 1536-4844electronic), 2005 Apr; 11(4): 376-382.
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Covelli EM, Brunetti A, Di Lauro A, Sullo P, Mazzarella G, Tedeschi E, Belfiore G
* Clinical impact of correlative [123I]-FP-CIT brain imaging and neurological findings in suspect Parkinson's disease (104 visite)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 2004 Oct; 108(4): 417-425.
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Varrone A, Pappata S, Quarantelli M, Sansone V, Mollica C, Lore E, Carlomagno S, Iavarone A, Postiglione A, Alfano B, Salvatore M
* Partial volume effect correction of rCBF SPET studies in mild cognitive impairment and Alzheimer's disease (117 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2004 Sep; 31: N/D-N/D.
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Rispo A, Imbriaco M, Celentano L, Cozzolino A, Mainenti PP, Camera L, Di Girolamo E, De Falco T, Castiglione F
* Small bowel Crohn's disease: Comparison of enteroclysis, bowel sonography and Tc-99m-HMPAO leukocyte scintigraphy (110 visite)
Eur Rev Med Pharmacol Sci (ISSN: 1128-3602), 2004 Sep; 8(5): 219-224.
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Caricasole A, Copani A, Caraci F, Aronica E, Rozemuller AJ, Caruso A, Storto M, Gaviraghi G, Terstappen GC, Nicoletti F
* Induction of Dickkopf-1, a negative modulator of the Wnt pathway, is associated with neuronal degeneration in Alzheimer's brain (110 visite)
Journal Of Neuroscience (ISSN: 0270-6474, 0361-803x), 2004 Jun 30; 24(26): 6021-6027.
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Rendina D, Mossetti G, Soscia E, Sirignano C, Insabato L, Viceconti R, Ignarra R, Salvatore M, Nunziata V
* Giant cell tumor and Paget's disease of bone in one family: geographic clustering (95 visite)
Clinical Orthopaedics And Related Research (ISSN: 0009-921x), 2004 Apr; (421): 218-224.
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Castiglione F, Rispo A, Imbriaco M, Celentano L, Cozzolino A, Camera L, Mainenti PP, Manguso F, Di Girolamo E, Mazzacca G
* Small bowel Crohn's disease: Enteroclysis, bowel sonography and Tc-99m-HMPAO leukocyte scintigraphy at comparison (95 visite)
Gastroenterology (ISSN: 0016-5085), 2004 Apr; 126(4): N/D-N/D.
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Varrone A, Pappata S, Amboni M, Pellecchia M, Salvatore E, Salvatore M
* Imaging of dopaminergic dysfunction with [I-123]FP-CIT SPECT in early-onset Parkinson's disease (93 visite)
Mov Disord (ISSN: 0885-3185, 1531-8257), 2004; 19: N/D-N/D.
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Covelli E, Brunetti A, Tedeschi E, Sullo P, Mazzarella G, Nuzzo M, Lombardi E, Di Lauro A, Belfiore G
* Parkinson's disease - Correlation between MRI analyses, perfusion SPECT with I-123FP-CIT SPECT and the clinical stage of the disease (89 visite)
Rivista Di Neuroradiologia (ISSN: 1120-9976), 2003 May; 16: N/D-N/D.
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Di Somma C, Pivonello R, Loche S, Faggiano A, Klain M, Salvatore M, Lombardi G, Colao A
* Effect of 2 years of cortisol normalization on the impaired bone mass and turnover in adolescent and adult patients with Cushing's disease: A prospective study (106 visite)
Clin Endocrinol (ISSN: 0300-0664, 1365-2265, 1365-2265electronic), 2003 Mar; 58(3): 302-308.
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Wiesehan K, Buder K, Linke RP, Patt S, Stoldt M, Unger E, Schmitt B, Bucci E, Willbold D
* Selection of D-amino-acid peptides that bind to Alzheimer's disease amyloid peptide Aβ1-42 by mirror image phage display (133 visite)
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2003; 4(8): 748-753.
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Varrone A, Pappata S, Caracò C, Soricelli A, Milan G, Quarantelli M, Alfano B, Postiglione A, Salvatore M
* Voxel-based comparison of rCBF SPET images in frontotemporal dementia and Alzheimer's disease highlights the involvement of different cortical networks (136 visite) (PDF 126 visite)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 2002 Nov; 29(11): 1447-1454.
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Pappata S, Varrone A, Caraco C, Soricelli A, Brunetti A, Milan G, Postiglione A, Alfano B, Salvatore M
* Voxel-based comparison of 99mTc-HMPAO SPECT images in Alzheimer and fronto-temporal dementia revealed distinct patterns of CBF alterations (97 visite)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 2001 Sep; 28(8): N/D-N/D.
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Camera L, Selva G, Puzziello A, Sparano L, Ignarra R, Quarantelli M
* [Castleman's disease: CT and MR findings in a case localized in the portocaval space] (91 visite)
Radiol Med (ISSN: 0033-8362, 1826-6983, 1826-6983electronic), 2001 Sep; 102(3): 186-188.
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Brunetti A, Postiglione A, Tedeschi E, Ciarmiello A, Quarantelli M, Covelli EM, Milan G, Larobina M, Soricelli A, Sodano A, Alfano B
Measurement of global brain atrophy in Alzheimer's disease with unsupervised segmentation of spin-echo MRI studies (179 visite) (PDF 155 visite)
J Magn Reson Imaging (ISSN: 1053-1807, 1522-2586electronic), 2000 Mar; 11(3): 260-266.
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Brunetti A, Postiglione A, Tedeschi E, Ciarmiello A, Quarantelli M, Covelli E, Milan G, Larobina M, Soricelli A, Sodano A, Alfano B
Measurement of global drain atrophy in Alzheimer's disease with unsupervised segmentation of spin-echo MRI studies (166 visite)
J Magn Reson Imaging (ISSN: 1053-1807, 1522-2586electronic), 2000 Mar; 11(3): N/D-N/D.
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Cirillo LC, Camera L, Della Noce M, Castiglione F, Mazzacca G, Salvatore M
Accuracy of enteroclysis in Crohn's disease of the small bowel: A retrospective study (92 visite)
Eur Radiol (ISSN: 0938-7994, 1432-1084electronic), 2000; 10(12): 1894-1898.
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Varrone A, Soricelli A, Postiglione A, Salvatore M
Comparison Between Cortical Distribution Of I-123 Iomazenil And Tc-99m Hmpao In Patients With Alzheimer'S Disease Using Spect (89 visite)
Clin Nucl Med, 1999 Sep; 24(9): 660-665.
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Varrone A, Soricelli A, Postiglione A, Salvatore M
Comparison between cortical distribution of I-123 lomazenil and Tc-99m HMPAO in patients with Alzheimer's disease using SPECT (100 visite)
Clin Nucl Med (ISSN: 0363-9762, 1536-0229, 1536-0229electronic), 1999 Sep; 24(9): 660-665.
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Messina G, Viceconti N, Trinti B
Diagnostic items and treatment of Plummer's disease: A study on 180 patients (101 visite)
Clinica Terapeutica (ISSN: 0009-9074), 1998 May; 149(3): 191-195.
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Postiglione A, Soricelli A, Grossi D, Romano M, Mainenti PP, Ruocco A, Fragrassi N, Chiacchio L, Milan G, De Chiara S, Brunetti A
Changes in cerebral blood flow during cognitive activation evaluated by single photon emission computed tomography in patients with Alzheimer's disease (93 visite)
Alzheimer S Res (ISSN: 1356-918x), 1997 Jun; 3(3): 93-99.
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Varrone A, Soricelli A, Postiglione A, Salvatore M, Lassen N
Benzodiazepine receptor distribution in Alzheimer's disease with (123)I-iomazenil by SPECT (98 visite)
Textbook Of Spect In Neurology And Psychiatry, 1997; N/D: N/D-N/D.
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Soricelli A, Varrone A, Acampa W, Postiglione A, Salvatore M, Lassen N
Brain perfusion with Tc-99m HMPAO and neuronal loss with 123-iomazenil in Alzheimer disease (102 visite)
Radiology (ISSN: 0033-8419, 1527-1315, 1527-1315electronic), 1996 Nov; 201: N/D-N/D.
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Soricelli A, Postiglione A, GrivetFojaja M, Mainenti PP, Discepolo A, Varrone A, Salvatore M, Lassen N
Reduced cortical distribution volume of iodine-123 iomazenil in Alzheimer's disease as a measure of loss of synapses (92 visite)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1996 Oct; 23(10): 1323-1328.
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Soricelli A, Postiglione A, Mainenti PP, GrivetFojaja M, Discepolo A, Varrone A, Salvatore M, Lassen N
Preliminary evaluation of distribution volume for 123I-Iomazenil in Alzheimer's disease as a measure of neuronal loss (84 visite)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1996 May; 37(5SUPPL.): N/D-N/D.
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NAPPI A, CUOCOLO A, MAROTTA T, FERRARA L, IAZZETTA N, PACE L, NICOLAI E, DEMICHELE G, SALVATORE M, CAMPANELLA G, POSTIGLIONE A
Usefulness of monitoring left ventricular function by an ambulatory radionuclide detector (VEST) in patients with Parkinson's disease and postural hypotension (78 visite)
Alzheimer S And Parkinson S Diseases (ISSN: 0099-9962), 1995; 44: N/D-N/D.
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SORICELLI A, TEDESCHI E, POSTIGLIONE A, GROSSI D, BRUNETTI A, ROMANO M, CASTELLI L, MAINENTI PP, SALVATORE M
BRAIN PERFUSION AT REST AND DURING COGNITIVE ACTIVATION IN PATIENTS WITH DEMENTIA OF ALZHEIMERS TYPE (100 visite)
J Nucl Med (ISSN: 0161-5505, 1535-5667, 1535-5667electronic), 1994 May; 35(5): N/D-N/D.
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Nappi A, Cuocolo A, Iazzetta N, Ferrara LA, Marotta T, Pace L, Nicolai E, De Michele G, Campanella G, Salvatore M, Postiglione A
Ambulatory monitoring of left ventricular function in patients with Parkinson's disease and postural hypotension (105 visite)
Eur J Nucl Med (ISSN: 0340-6997, 1619-7070, 1619-7089), 1994; 21(12): 1312-1317.
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85 Records (66 escludendo Abstract e Conferenze).
Impact factor totale: 278.794 (218.522 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 302.125 (225.866 escludendo Abstract e Conferenze).







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