Cisplatin encapsulation within a ferritin nanocage: A high-resolution crystallographic study (208 views visite)
Chem Commun (ISSN: 1359-7345, 1364-548x, 1364-548xelectronic), 2016; 52(22): 4136-4139.
Export to Esporta in BibTeX Export to Esporta in EndNote
Paper type Tipo di articolo: Journal Article,
Impact factor: 6.319, 5-year impact factor Impact factor a 5 anni: 6.238
Url: https://www2.scopus.com/inward/record.uri?eid=2-s2.0-84960510052&partnerID=40&md5=5afef67189930c655b6c607a681d956d
Keywords Parole chiave: Not available. Non disponibili.
Affiliations Affiliazioni:
*** IBB - CNR ***
Department of Chemical Sciences, University of Naples Federico II, Complesso Universitario di Monte sant'Angelo, Via Cintia, Napoli, Italy
Department of Chemistry, University of Florence, Via della Lastruccia 3, Sesto Fiorentino, FI, Italy
CNR Institute of Biostructures and Bioimages, Via Mezzocannone 16, Napoli, Italy
References Riferimenti:
Siddik, Z.H., (2003) Oncogene, 22, pp. 7265-727
Kelland, L., (2007) Nat. Rev. Cancer, 7, pp. 573-584
Green, M.H., (1992) J. Natl. Cancer Inst., 84, pp. 306-312
Sanderson, B.J.S., Ferguson, L.R., Denny, W.A., (1996) Mutat. Res., Fundam. Mol. Mech. Mutagen., 355, pp. 59-70
Rixe, O., Ortuzar, W., Alvarez, M., Parker, R., Reed, E., Paull, K., Fojo, T., (1996) Biochem. Pharmacol., 52, pp. 1855-1865
Todd, R.C., Lippard, S.J., (2009) Metallomics, 1, pp. 280-291
Wang, D., Lippard, S.J., (2005) Nat. Rev. Drug Discovery, 4, pp. 307-320
Zhai, X., Beckmann, H., Jantzen, H.-M., Essigmann, J.M., (1998) Biochemistry, 37, pp. 16307-16315
Eastman, A., (1987) Pharmacol. Ther., 34, pp. 155-166
Ohndorf, M., Rould, M.A., He, Q., Pabo, C.O., Lippard, S.J., (1999) Nature, 399, pp. 708-712
Raymond, E., Faivre, S., Chaney, S., Woynarowski, J., Cvitkovic, E., (2002) Mol. Cancer Ther., 1, pp. 227-235
Zhang, Y., Orner, B.P., (2011) Int. J. Mol. Sci., 12, pp. 5406-5421
Maity, B., Fujita, K., Ueno, T., (2015) Curr. Opin. Chem. Biol., 25, pp. 88-97
Zhen, Z., Tang, W., Todd, T., Xie, J., (2014) Expert Opin. Drug Delivery, 11, pp. 1913-1922
Heger, Z., Skalickova, S., Zitka, O., Adam, V., Kizek, R., (2014) Nanomedicine, 9, pp. 2233-2245
Liu, G.D., Wang, J., Lea, S.A., Lin, Y.H., (2006) ChemBioChem, 7, pp. 1315-1319
He, D., Marles-Wright, J., (2015) New Biotechnol., 32 (6), pp. 651-657
Uchida, M., Klem, M.T., Allen, M., Suci, P., Flenniken, M., Gillitzer, E., Varpness, Z., Douglas, T., (2007) Adv. Mater., 19, pp. 1025-1042
Yan, F., Zhang, Y., Yuan, H.K., Gregas, M.K., VoDihn, T., (2008) Chem. Commun., pp. 4579-4581
Li, L., Fang, C.J., Ryan, J.C., Niemi, E.C., Lebrón, J.A., Björkman, P.J., Arase, H., Seaman, W.E., (2010) Proc. Natl. Acad. Sci. U. S. A., 107 (8), pp. 3505-3510
Valero, E., Tambalo, S., Marzola, P., Ortega-Munoz, M., Lopez-Jaramillo, F.J., Santoyo-Gonzalez, F., Lopez, J.D., Galvez, N., (2011) J. Am. Chem. Soc., 133, pp. 4889-4895
Fan, K., Cao, C., Pan, Y., Lu, D., Yang, D., Feng, J., Song, L., Yan, X., (2012) Nat. Nanotechnol., 7, pp. 459-464
Kang, H.J., Kang, Y.J., Lee, Y.M., Shin, H.H., Chung, S.J., Kang, S., (2012) Biomaterials, 33, pp. 5423-5430
Moss, D., Fargion, S., Francanzani, A.L., Levi, S., Cappelini, M.D., Arosio, P., Powell, L.W., Halliday, J.W., (1992) J. Inorg. Biochem., 47, pp. 219-227
Fargion, S., Fracanzani, A.L., Brando, B., Arosio, P., Levi, S., Fiorelli, G., (1991) Blood, 78, pp. 1056-1061
Fisher, J., Devraj, K., Ingram, J., Slagle-Webb, B., Madhanku, A.B., Liu, X., Klinger, M., Connor, J.R., (2007) Am. J. Physiol.: Cell Physiol., 293, pp. C641-C649
Fan, K., Gao, L., Yan, X., (2013) Wiley Interdiscip. Rev.: Nanomed. Nanobiotechnol., 5, pp. 287-298
Pasquini, J.M., Aires, B., (2002) Dev. Neurosci., 24, pp. 94-251. , Springer
Bretscher, M.S., Thompson, J.N., (1983) EMBO J., 2, pp. 5599-5603
Hulet, S.W., Powers, S., Connor, J.R., (1999) J. Neurol. Sci., 165, pp. 48-55
Yang, Z., Wang, X., Diao, H., Zhang, J., Li, H., Sun, H., Guo, Z., (2007) Chem. Commun., pp. 3453-3455
Xing, R.M., Wang, X.Y., Zhang, C.L., Zhang, Y.M., Wang, Q., Yang, Z., Guo, Z.J., (2009) J. Inorg. Biochem., 103, pp. 1039-1044
Ji, X.-T., Huang, L., Huang, H.-Q., (2012) J. Proteomics, 75, pp. 3145-3157
Falvo, E., Tremante, E., Fraioli, R., Leonetti, C., Zamparelli, C., Boffi, A., Morea, V., Giacomini, P., (2013) Nanoscale, 5, pp. 12278-12285
Uchida, M., Kanga, S., Reichhardta, C., Harlen, K., Douglas, T., (2010) Biochim. Biophys. Acta, 1800, pp. 834-845
Wang, W., Knovich, M.A., Coffman, L.G., Torti, F.M., Torti, S.V., (2010) Biochim. Biophys. Acta, 1800, pp. 760-769
Andrews, S.C., Arosio, P., Bottke, W., Briat, J.F., Vondarl, M., Harrison, P.M., Laulhere, J.P., Yewdall, S.J., (1992) J. Inorg. Biochem., 47, pp. 161-174
Aime, S., Frullano, L., Crich, S.G., (2002) Angew. Chem., Int. Ed., 41, pp. 1017-1019
Cutrin, J.C., Crich, S.G., Burghelea, D., Dastru, W., Aime, S., (2013) Mol. Pharmaceutics, 10 (5), pp. 2079-2085
Dominguez-Vera, J.M., (2004) J. Inorg. Biochem., 98, pp. 469-472
Ueno, T., Suzuki, M., Goto, T., Matsumoto, T., Nagayama, K., Watanabe, Y., (2004) Angew. Chem., Int. Ed., 43, pp. 2527-2530
Li, M., Viravaidya, C., Mann, S., (2007) Small, 3, pp. 1477-1481
Iwahori, K., Yoshizawa, K., Muraoka, M., Yamashita, I., (2005) Inorg. Chem., 44, pp. 6393-6400
Pulsipher, K.W., Dmochovski, I.J., (2015) Methods Mol. Biol., 1252, pp. 27-37
Liang, M., Fan, K., Zhou, M., Duan, S., Zheng, J., Yang, D., Feng, J., Yan, X., (2014) Proc. Natl. Acad. Sci. U. S. A., 111 (41), pp. 14900-14905
Polanams, J., Ray, A.D., Watt, R.K., (2005) Inorg. Chem., 44, pp. 3203-3209
Kilic, M.A., Ozlu, E., Callis, S., (2012) J. Biomed. Nanotechnol., 8, pp. 508-514
Uchida, M., Flenniken, M.L., Allen, M., Willits, D.A., Crowley, B.E., Brumfield, S., Willis, A.F., Douglas, T., (2006) J. Am. Chem. Soc., 128 (51), pp. 16626-16633
Chen, L., Bai, G., Yang, R., Zang, J., Zhou, T., Zhao, G., (2014) Food Chem., 149, pp. 307-312
Kim, M., Rho, Y., Sik Jin, K., Ahn, B., Jung, S., Kim, H., Ree, M., (2011) Biomacromolecules, 12 (5), pp. 1629-1640
Karplus, P.A., Diederichs, K., (2012) Science, 336 (6084), pp. 1030-1033
Diederichs, K., Karplus, P.A., (2013) Acta Crystallogr., Sect. D: Biol. Crystallogr., 69, pp. 1215-1222
Ka Rplus, P.A., Diederichs, K., (2015) Curr. Opin. Struct. Biol., 34, pp. 60-68
Tanley, S.W.M., Schreurs, A.M.M., Kroon-Batenburg, L.M.J., Helliwell, J., (2016) Acta Crystallogr., Sect. F: Struct. Biol. Commun.
McCoy, A.J., Grosse-Kunstleve, R.W., Adams, P.D., Winn, M.D., Storoni, L.C., Read, R.J., (2007) J. Appl. Crystallogr., 40, pp. 658-674
De Val, N., Declercq, J.P., Lim, C.K., Crichton, R.R., (2012) J. Inorg. Biochem., 112, pp. 77-84
Murshudov, G.N., Skubak, P., Lebedev, A.A., Pannu, N.S., Steiner, R.A., Nicholls, R.A., Winn, M.D., Vagin, A.A., (2011) Acta Crystallogr., Sect. D: Biol. Crystallogr., 67, pp. 355-367
Ueno, T., Abe, M., Hirata, K., Abe, S., Suzuki, M., Shimizu, N., Yakamoto, M., Watanabe, Y., (2009) J. Am. Chem. Soc., 131, p. 5094
Suzuki, M., Abe, M., Ueno, T., Abe, S., Goto, T., Toda, Y., Akita, T., Watanabe, Y., (2009) Chem. Commun., pp. 4871-4873
Pozzi, C., Di Pisa, F., Bernacchioni, C., Ciambellotti, S., Turano, P., Mangani, S., (2015) Acta Crystallogr., Sect. D: Biol. Crystallogr., 71, pp. 1909-1920
Casini, A., Mastrobuoni, G., Temperini, C., Gabbiani, C., Francese, S., Moneti, G., Supuran, C.T., Messori, L., (2007) Chem. Commun., pp. 156-158
Tanley, S.W.M., Diederichs, K., Kroon-Batenburg, L.M., Levy, C., Schreurs, A.M., Helliwell, J.R., (2014) Acta Crystallogr., Sect. F: Struct. Biol. Commun., 70, pp. 1135-1142
Helliwell, J.R., Tanley, S.W.M., (2013) Acta Crystallogr., Sect. D: Biol. Crystallogr., 69, pp. 121-125
Marasco, D., Messori, L., Marzo, T., Merlino, A., (2015) Dalton Trans., 44 (22), pp. 10392-10398
Calderone, V., Casini, A., Mangani, S., Messori, L., Orioli, P.L., (2006) Angew. Chem., 45, pp. 1267-1269
Picone, D., Donnarumma, F., Ferraro, G., Russo Krauss, I., Fagagnini, A., Gotte, G., Merlino, A., (2015) J. Inorg. Biochem., 146, pp. 37-43
Ferraro, G., Massai, L., Messori, L., Merlino, A., (2015) Chem. Commun., 51 (46), pp. 9436-9439
Hempstead, P.D., Yewdall, S.J., Fernie, A.R., Lawson, D.M., Artymiuk, P.J., Rice, D.W., Ford, G.C., Harrison, P.M., (1997) J. Mol. Biol., 268 (2), pp. 424-448
Fujita, K., Tanaka, Y., Sho, T., Ozeki, S., Abe, S., Hikage, T., Kuchimaru, T., Ueno, T., (2014) J. Am. Chem. Soc., 136 (48), pp. 16902-16908
Chem Commun (ISSN: 1359-7345, 1364-548x, 1364-548xelectronic), 2016; 52(22): 4136-4139.
Export to Esporta in BibTeX Export to Esporta in EndNote
Paper type Tipo di articolo: Journal Article,
Impact factor: 6.319, 5-year impact factor Impact factor a 5 anni: 6.238
Url: https://www2.scopus.com/inward/record.uri?eid=2-s2.0-84960510052&partnerID=40&md5=5afef67189930c655b6c607a681d956d
Keywords Parole chiave: Not available. Non disponibili.
Affiliations Affiliazioni:
*** IBB - CNR ***
Department of Chemical Sciences, University of Naples Federico II, Complesso Universitario di Monte sant'Angelo, Via Cintia, Napoli, Italy
Department of Chemistry, University of Florence, Via della Lastruccia 3, Sesto Fiorentino, FI, Italy
CNR Institute of Biostructures and Bioimages, Via Mezzocannone 16, Napoli, Italy
References Riferimenti:
Siddik, Z.H., (2003) Oncogene, 22, pp. 7265-727
Kelland, L., (2007) Nat. Rev. Cancer, 7, pp. 573-584
Green, M.H., (1992) J. Natl. Cancer Inst., 84, pp. 306-312
Sanderson, B.J.S., Ferguson, L.R., Denny, W.A., (1996) Mutat. Res., Fundam. Mol. Mech. Mutagen., 355, pp. 59-70
Rixe, O., Ortuzar, W., Alvarez, M., Parker, R., Reed, E., Paull, K., Fojo, T., (1996) Biochem. Pharmacol., 52, pp. 1855-1865
Todd, R.C., Lippard, S.J., (2009) Metallomics, 1, pp. 280-291
Wang, D., Lippard, S.J., (2005) Nat. Rev. Drug Discovery, 4, pp. 307-320
Zhai, X., Beckmann, H., Jantzen, H.-M., Essigmann, J.M., (1998) Biochemistry, 37, pp. 16307-16315
Eastman, A., (1987) Pharmacol. Ther., 34, pp. 155-166
Ohndorf, M., Rould, M.A., He, Q., Pabo, C.O., Lippard, S.J., (1999) Nature, 399, pp. 708-712
Raymond, E., Faivre, S., Chaney, S., Woynarowski, J., Cvitkovic, E., (2002) Mol. Cancer Ther., 1, pp. 227-235
Zhang, Y., Orner, B.P., (2011) Int. J. Mol. Sci., 12, pp. 5406-5421
Maity, B., Fujita, K., Ueno, T., (2015) Curr. Opin. Chem. Biol., 25, pp. 88-97
Zhen, Z., Tang, W., Todd, T., Xie, J., (2014) Expert Opin. Drug Delivery, 11, pp. 1913-1922
Heger, Z., Skalickova, S., Zitka, O., Adam, V., Kizek, R., (2014) Nanomedicine, 9, pp. 2233-2245
Liu, G.D., Wang, J., Lea, S.A., Lin, Y.H., (2006) ChemBioChem, 7, pp. 1315-1319
He, D., Marles-Wright, J., (2015) New Biotechnol., 32 (6), pp. 651-657
Uchida, M., Klem, M.T., Allen, M., Suci, P., Flenniken, M., Gillitzer, E., Varpness, Z., Douglas, T., (2007) Adv. Mater., 19, pp. 1025-1042
Yan, F., Zhang, Y., Yuan, H.K., Gregas, M.K., VoDihn, T., (2008) Chem. Commun., pp. 4579-4581
Li, L., Fang, C.J., Ryan, J.C., Niemi, E.C., Lebrón, J.A., Björkman, P.J., Arase, H., Seaman, W.E., (2010) Proc. Natl. Acad. Sci. U. S. A., 107 (8), pp. 3505-3510
Valero, E., Tambalo, S., Marzola, P., Ortega-Munoz, M., Lopez-Jaramillo, F.J., Santoyo-Gonzalez, F., Lopez, J.D., Galvez, N., (2011) J. Am. Chem. Soc., 133, pp. 4889-4895
Fan, K., Cao, C., Pan, Y., Lu, D., Yang, D., Feng, J., Song, L., Yan, X., (2012) Nat. Nanotechnol., 7, pp. 459-464
Kang, H.J., Kang, Y.J., Lee, Y.M., Shin, H.H., Chung, S.J., Kang, S., (2012) Biomaterials, 33, pp. 5423-5430
Moss, D., Fargion, S., Francanzani, A.L., Levi, S., Cappelini, M.D., Arosio, P., Powell, L.W., Halliday, J.W., (1992) J. Inorg. Biochem., 47, pp. 219-227
Fargion, S., Fracanzani, A.L., Brando, B., Arosio, P., Levi, S., Fiorelli, G., (1991) Blood, 78, pp. 1056-1061
Fisher, J., Devraj, K., Ingram, J., Slagle-Webb, B., Madhanku, A.B., Liu, X., Klinger, M., Connor, J.R., (2007) Am. J. Physiol.: Cell Physiol., 293, pp. C641-C649
Fan, K., Gao, L., Yan, X., (2013) Wiley Interdiscip. Rev.: Nanomed. Nanobiotechnol., 5, pp. 287-298
Pasquini, J.M., Aires, B., (2002) Dev. Neurosci., 24, pp. 94-251. , Springer
Bretscher, M.S., Thompson, J.N., (1983) EMBO J., 2, pp. 5599-5603
Hulet, S.W., Powers, S., Connor, J.R., (1999) J. Neurol. Sci., 165, pp. 48-55
Yang, Z., Wang, X., Diao, H., Zhang, J., Li, H., Sun, H., Guo, Z., (2007) Chem. Commun., pp. 3453-3455
Xing, R.M., Wang, X.Y., Zhang, C.L., Zhang, Y.M., Wang, Q., Yang, Z., Guo, Z.J., (2009) J. Inorg. Biochem., 103, pp. 1039-1044
Ji, X.-T., Huang, L., Huang, H.-Q., (2012) J. Proteomics, 75, pp. 3145-3157
Falvo, E., Tremante, E., Fraioli, R., Leonetti, C., Zamparelli, C., Boffi, A., Morea, V., Giacomini, P., (2013) Nanoscale, 5, pp. 12278-12285
Uchida, M., Kanga, S., Reichhardta, C., Harlen, K., Douglas, T., (2010) Biochim. Biophys. Acta, 1800, pp. 834-845
Wang, W., Knovich, M.A., Coffman, L.G., Torti, F.M., Torti, S.V., (2010) Biochim. Biophys. Acta, 1800, pp. 760-769
Andrews, S.C., Arosio, P., Bottke, W., Briat, J.F., Vondarl, M., Harrison, P.M., Laulhere, J.P., Yewdall, S.J., (1992) J. Inorg. Biochem., 47, pp. 161-174
Aime, S., Frullano, L., Crich, S.G., (2002) Angew. Chem., Int. Ed., 41, pp. 1017-1019
Cutrin, J.C., Crich, S.G., Burghelea, D., Dastru, W., Aime, S., (2013) Mol. Pharmaceutics, 10 (5), pp. 2079-2085
Dominguez-Vera, J.M., (2004) J. Inorg. Biochem., 98, pp. 469-472
Ueno, T., Suzuki, M., Goto, T., Matsumoto, T., Nagayama, K., Watanabe, Y., (2004) Angew. Chem., Int. Ed., 43, pp. 2527-2530
Li, M., Viravaidya, C., Mann, S., (2007) Small, 3, pp. 1477-1481
Iwahori, K., Yoshizawa, K., Muraoka, M., Yamashita, I., (2005) Inorg. Chem., 44, pp. 6393-6400
Pulsipher, K.W., Dmochovski, I.J., (2015) Methods Mol. Biol., 1252, pp. 27-37
Liang, M., Fan, K., Zhou, M., Duan, S., Zheng, J., Yang, D., Feng, J., Yan, X., (2014) Proc. Natl. Acad. Sci. U. S. A., 111 (41), pp. 14900-14905
Polanams, J., Ray, A.D., Watt, R.K., (2005) Inorg. Chem., 44, pp. 3203-3209
Kilic, M.A., Ozlu, E., Callis, S., (2012) J. Biomed. Nanotechnol., 8, pp. 508-514
Uchida, M., Flenniken, M.L., Allen, M., Willits, D.A., Crowley, B.E., Brumfield, S., Willis, A.F., Douglas, T., (2006) J. Am. Chem. Soc., 128 (51), pp. 16626-16633
Chen, L., Bai, G., Yang, R., Zang, J., Zhou, T., Zhao, G., (2014) Food Chem., 149, pp. 307-312
Kim, M., Rho, Y., Sik Jin, K., Ahn, B., Jung, S., Kim, H., Ree, M., (2011) Biomacromolecules, 12 (5), pp. 1629-1640
Karplus, P.A., Diederichs, K., (2012) Science, 336 (6084), pp. 1030-1033
Diederichs, K., Karplus, P.A., (2013) Acta Crystallogr., Sect. D: Biol. Crystallogr., 69, pp. 1215-1222
Ka Rplus, P.A., Diederichs, K., (2015) Curr. Opin. Struct. Biol., 34, pp. 60-68
Tanley, S.W.M., Schreurs, A.M.M., Kroon-Batenburg, L.M.J., Helliwell, J., (2016) Acta Crystallogr., Sect. F: Struct. Biol. Commun.
McCoy, A.J., Grosse-Kunstleve, R.W., Adams, P.D., Winn, M.D., Storoni, L.C., Read, R.J., (2007) J. Appl. Crystallogr., 40, pp. 658-674
De Val, N., Declercq, J.P., Lim, C.K., Crichton, R.R., (2012) J. Inorg. Biochem., 112, pp. 77-84
Murshudov, G.N., Skubak, P., Lebedev, A.A., Pannu, N.S., Steiner, R.A., Nicholls, R.A., Winn, M.D., Vagin, A.A., (2011) Acta Crystallogr., Sect. D: Biol. Crystallogr., 67, pp. 355-367
Ueno, T., Abe, M., Hirata, K., Abe, S., Suzuki, M., Shimizu, N., Yakamoto, M., Watanabe, Y., (2009) J. Am. Chem. Soc., 131, p. 5094
Suzuki, M., Abe, M., Ueno, T., Abe, S., Goto, T., Toda, Y., Akita, T., Watanabe, Y., (2009) Chem. Commun., pp. 4871-4873
Pozzi, C., Di Pisa, F., Bernacchioni, C., Ciambellotti, S., Turano, P., Mangani, S., (2015) Acta Crystallogr., Sect. D: Biol. Crystallogr., 71, pp. 1909-1920
Casini, A., Mastrobuoni, G., Temperini, C., Gabbiani, C., Francese, S., Moneti, G., Supuran, C.T., Messori, L., (2007) Chem. Commun., pp. 156-158
Tanley, S.W.M., Diederichs, K., Kroon-Batenburg, L.M., Levy, C., Schreurs, A.M., Helliwell, J.R., (2014) Acta Crystallogr., Sect. F: Struct. Biol. Commun., 70, pp. 1135-1142
Helliwell, J.R., Tanley, S.W.M., (2013) Acta Crystallogr., Sect. D: Biol. Crystallogr., 69, pp. 121-125
Marasco, D., Messori, L., Marzo, T., Merlino, A., (2015) Dalton Trans., 44 (22), pp. 10392-10398
Calderone, V., Casini, A., Mangani, S., Messori, L., Orioli, P.L., (2006) Angew. Chem., 45, pp. 1267-1269
Picone, D., Donnarumma, F., Ferraro, G., Russo Krauss, I., Fagagnini, A., Gotte, G., Merlino, A., (2015) J. Inorg. Biochem., 146, pp. 37-43
Ferraro, G., Massai, L., Messori, L., Merlino, A., (2015) Chem. Commun., 51 (46), pp. 9436-9439
Hempstead, P.D., Yewdall, S.J., Fernie, A.R., Lawson, D.M., Artymiuk, P.J., Rice, D.W., Ford, G.C., Harrison, P.M., (1997) J. Mol. Biol., 268 (2), pp. 424-448
Fujita, K., Tanaka, Y., Sho, T., Ozeki, S., Abe, S., Hikage, T., Kuchimaru, T., Ueno, T., (2014) J. Am. Chem. Soc., 136 (48), pp. 16902-16908
Cisplatin encapsulation within a ferritin nanocage: A high-resolution crystallographic study
Cisplatin (CDDP) can be encapsulated within the central cavity of reconstituted (apo)ferritin, (A)Ft, to form a drug-loaded protein of potential great interest for targeted cancer treatments. In this study, the interactions occurring between cisplatin and native horse spleen Ft in CDDP-encapsulated AFt are investigated by high-resolution X-ray crystallography. A protein bound Pt center is unambiguously identified in AFt subunits by comparative analysis of difference Fourier electron density maps and of anomalous dispersion data. Indeed, a [Pt(NH3)2H2O]2+ fragment is found coordinated to the His132 residue located on the inner surface of the large AFt spherical cage. Remarkably, Pt binding does not alter the overall physicochemical features (shape, volume, polarity/hydrophobicity and electrostatic potential) of the outer surface of the AFt nanocage. CDDP-encapsulated AFt appears to be an ideal nanocarrier for CDDP delivery to target sites, as it possesses high biocompatibility and can be internalized by receptor mediated endocytosis, thus carrying the drug to tumor tissue with higher selectivity than free CDDP. © The Royal Society of Chemistry 2016.
Cisplatin (CDDP) can be encapsulated within the central cavity of reconstituted (apo)ferritin, (A)Ft, to form a drug-loaded protein of potential great interest for targeted cancer treatments. In this study, the interactions occurring between cisplatin and native horse spleen Ft in CDDP-encapsulated AFt are investigated by high-resolution X-ray crystallography. A protein bound Pt center is unambiguously identified in AFt subunits by comparative analysis of difference Fourier electron density maps and of anomalous dispersion data. Indeed, a [Pt(NH3)2H2O]2+ fragment is found coordinated to the His132 residue located on the inner surface of the large AFt spherical cage. Remarkably, Pt binding does not alter the overall physicochemical features (shape, volume, polarity/hydrophobicity and electrostatic potential) of the outer surface of the AFt nanocage. CDDP-encapsulated AFt appears to be an ideal nanocarrier for CDDP delivery to target sites, as it possesses high biocompatibility and can be internalized by receptor mediated endocytosis, thus carrying the drug to tumor tissue with higher selectivity than free CDDP. © The Royal Society of Chemistry 2016.
Cisplatin encapsulation within a ferritin nanocage: A high-resolution crystallographic study
Cisplatin encapsulation within a ferritin nanocage: A high-resolution crystallographic study
Alterio V, Langella E, Buonanno M, Esposito D, Nocentini A, Berrino E, Bua S, Polentarutti M, Supuran CT, Monti SM, De Simone G
* Zeta-carbonic anhydrases show CS(2) hydrolase activity: A new metabolic carbon acquisition pathway in diatoms? (5 visite)
Comput Struct Biotechnol J (ISSN: 2001-0370linking), 2021 Jun 5; 19: 3427-3436.
Impact Factor: 7.271
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Wang L, Bateman B, Zanetti-domingues L, Moores A, L , Astbury S, Spindloe C, Darrow M, C , Romano M, Needham S, R , Beis K, Rolfe D, J , Clarke D, T , Martin-fernandez M, L
Solid immersion microscopy images cells under cryogenic conditions with 12 nm resolution (70 visite)
Commun Biol, 2019 Feb 21; 2:74: N/D-N/D.
Impact Factor: 0
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Barbuto L, Di Serafino M, Della Vecchia N, Rea G, Esposito F, Vezzali N, Ferro F, Caprio MG, Vola EA, Romeo V, Vallone G
* Pediatric musculoskeletal ultrasound: a pictorial essay (147 visite) (PDF 78 visite)
J Ultrasound (ISSN: 1876-7931linking, 1876-7931electronic), 2018 Nov 9; N/D: N/D-N/D.
Impact Factor: 1.53
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Squeglia F, Berisio R, Ruggiero A
* The novel thermostable cellulose-degrading enzyme DtCel5H from Dictyoglomus thermophilum: crystallization and X-ray crystallographic analysis (314 visite)
Acta Crystallogr F Struct Biol Commun (ISSN: 2053-230xelectronic, 2053-230xlinking), 2018 Jan 1; 74(Pt1): 1-5.
Impact Factor: 0.8
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De Simone G, Langella E, Esposito D, Supuran CT, Monti SM, Winum JY, Alterio V
* Insights into the binding mode of sulphamates and sulphamides to hCA II: crystallographic studies and binding free energy calculations (227 visite)
J Enzym Inhib Med Ch (ISSN: 1475-6366, 1475-6374electronic, 1475-6366linking), 2017 Dec; 32(1): 1002-1011.
Impact Factor: 3.638
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Sgarlata C, Mugridge JS, Pluth MD, Zito V, Arena G, Raymond KN
* Different and Often Opposing Forces Drive the Encapsulation and Multiple Exterior Binding of Charged Guests to a M4 L6 Supramolecular Vessel in Water (236 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2017 Nov 27; 23(66): 16813-16818.
Impact Factor: 5.16
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Galati C, Spinella N, Renna L, Milardi D, Attanasio F, Sciacca MFM, Bongiorno C
* Strategy to discover full-length amyloid-beta peptide ligands using high-efficiency microarray technology (388 visite)
Beilstein J Nanotech (ISSN: 2190-4286), 2017 Nov 20; 8(1): 2446-2453.
Impact Factor: 2.968
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Vullo D, Supuran CT, Scozzafava A, De Simone G, Monti SM, Alterio V, Carta F
* Kinetic and X-ray crystallographic investigations of substituted 2-thio-6-oxo-1, 6-dihydropyrimidine-benzenesulfonamides acting as carbonic anhydrase inhibitors (231 visite)
Bioorg Med Chem (ISSN: 0968-0896, 1464-3391), 2016 Aug 15; 24(16): 3643-3648.
Impact Factor: 2.93
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Di Fiore A, De Simone G, Alterio V, Riccio V, Winum JY, Carta F, Supuran CT
* The anticonvulsant sulfamide JNJ-26990990 and its S, S-dioxide analog strongly inhibit carbonic anhydrases: solution and X-ray crystallographic studies (218 visite)
Org Biomol Chem (ISSN: 1477-0520, 1477-0539, 1477-0539electronic), 2016 Jun 07; 14(21): 4853-4858.
Impact Factor: 3.564
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Langella E, D'Ambrosio K, D'Ascenzio M, Carradori S, Monti SM, Supuran CT, De Simone G
* A Combined Crystallographic and Theoretical Study Explains the Capability of Carboxylic Acids to Adopt Multiple Binding Modes in the Active Site of Carbonic Anhydrases (300 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2016 Jan 4; 22(1): 97-100.
Impact Factor: 5.317
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Ringhieri P, Avitabile C, Saviano M, Morelli G, Romanelli A, Accardo A
* The influence of liposomal formulation on the incorporation and retention of PNA oligomers (156 visite)
Colloid Surface B (ISSN: 0927-7765), 2016; 145: 462-469.
Impact Factor: 3.887
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Borrelli P, Palma G, Tedeschi E, Cocozza S, Comerci M, Alfano B, Haacke EM, Salvatore M
* Improving Signal-to-Noise Ratio in Susceptibility Weighted Imaging: A Novel Multicomponent Non-Local Approach (416 visite) (PDF 230 visite)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2015 Jun 1; 10(6): e0126835-e0126835.
Impact Factor: 3.057
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Scotto di Santolo M, Sagnelli M, Mancini M, Scalvenzi M, Delfino M, Schonauer F, Molea G, Ayala F, Salvatore M
* Erratum to: High-resolution color-Doppler ultrasound for the study of skin growths (254 visite)
Arch Dermatol Res (ISSN: 0340-3696), 2015 Apr 7; Epub: N/D-N/D.
Impact Factor: 2.146
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Alterio V, Tanc M, Ivanova J, Zalubovskis R, Vozny I, Monti SM, Di Fiore A, De Simone G, Supuran CT
* X-ray crystallographic and kinetic investigations of 6-sulfamoyl-saccharin as a carbonic anhydrase inhibitor (316 visite)
Org Biomol Chem (ISSN: 1477-0520, 1477-0539, 1477-0539electronic), 2015 Apr 7; 13(13): 4064-4069.
Impact Factor: 3.559
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Avino S, D'Avino V, Giorgini A, Pacelli R, Liuzzi R, Cella L, De Natale P, Gagliardi G
* Ionizing radiation detectors based on ge-doped optical fibers inserted in resonant cavities (291 visite)
Sensors (ISSN: 1424-8220, 1424-3210, 1424-8220linking), 2015 Feb 12; 15(2): 4242-4252.
Impact Factor: 2.033
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Scotto di Santolo M, Sagnelli M, Mancini M, Scalvenzi M, Delfino M, Schonauer F, Molea G, Ayala F, Salvatore M
* High-resolution color-Doppler ultrasound for the study of skin growths (283 visite)
Arch Dermatol Res (ISSN: 0340-3696), 2015 Jan 21; Epub: N/D-N/D.
Impact Factor: 2.146
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Troise AD, Fiore A, Roviello GN, Monti SM, Fogliano V
* Simultaneous quantification of amino acids and Amadori products in foods through ion-pairing liquid chromatography-high-resolution mass spectrometry (808 visite)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2015 Jan; 47(1): 111-124.
Impact Factor: 3.196
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Nardon C, Boscutti G, Dalla Via L, Ringhieri P, Di Noto V, Morelli G, Accardo A, Fregona D
* CCK8 peptide-labeled Pluronic® F127 micelles as a targeted vehicle of gold-based anticancer chemotherapeutics (356 visite)
Medchemcomm (ISSN: 2040-2503), 2015; 6(1): 155-163.
Impact Factor: 2.319
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Avitabile C, Accardo A, Ringhieri P, Morelli G, Saviano M, Montagner G, Fabbri E, Gallerani E, Gambari R, Romanelli A
* Incorporation of Naked Peptide Nucleic Acids into Liposomes Leads to Fast and Efficient Delivery (411 visite)
Bioconjug Chem (ISSN: 1043-1802, 1520-4812), 2015; 26(8): 1533-1541.
Impact Factor: 4.5
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Mügge C, Marzo T, Massai L, Hildebrandt J, Ferraro G, Rivera-Fuentes P, Metzler-Nolte N, Merlino A, Messori L, Weigand W
* Platinum(II) Complexes with O, S Bidentate Ligands: Biophysical Characterization, Antiproliferative Activity, and Crystallographic Evidence of Protein Binding (300 visite)
Inorg Chem (ISSN: 0020-1669, 1520-510x, 0020-1669linking), 2015; 54(17): 8560-8570.
Impact Factor: 4.82
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Ringhieri P, Iannitti R, Nardon C, Palumbo R, Fregona D, Morelli G, Accardo A
* Target selective micelles for bombesin receptors incorporating Au(III)-dithiocarbamato complexes (359 visite)
Int J Pharm (ISSN: 0378-5173, 1873-3476), 2014 Oct 1; 473(1-2): 194-202.
Impact Factor: 3.65
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Merlino A, Vergara A, Vitagliano L
* Comments on Structural studies of haemoglobin from pisces species shortfin mako shark (Isurus oxyrinchus) at 1. 9 angstrom resolution by P. Ramesh et al. (2013). J. Synchrotron Rad. 20, 843-847 (255 visite)
J Synchrotron Radiat (ISSN: 0909-0495), 2014 Jul; 21: N/D-N/D.
Impact Factor: 2.794
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Santamaria F, Esposito M, Montella S, Cantone E, Mollica C, De Stefano S, Mirra V, Carotenuto M
* Sleep disordered breathing and airway disease in primary ciliary dyskinesia (450 visite)
Respirology (ISSN: 1323-7799, 1440-1843electronic), 2014 May; 19(4): 570-575.
Impact Factor: 3.345
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Accardo A, Aloj L, Aurilio M, Morelli G, Tesauro D
* Receptor binding peptides for target-selective delivery of nanoparticles encapsulated drugs (514 visite)
Int J Nanomed (ISSN: 1178-2013, 1176-9114, 1176-9114linking), 2014 Mar 27; 9(1): 1537-1557.
Impact Factor: 4.383
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Squeglia F, Bachert B, De Simone A, Lukomski S, Berisio R
* The crystal structure of the streptococcal collagen-like protein 2 globular domain from invasive M3-type group a streptococcus shows significant similarity to immunomodulatory HIV protein gp41 (371 visite)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2014 Feb 21; 289(8): 5122-5133.
Impact Factor: 4.573
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Mancini M, Palma G, Tedeschi E, Greco A, Ragucci M
* Extracranial Brain Draining Veins In Mouse: Assessment By High Resolution Ultrasound And Mr Angiography Of The Neck (242 visite) (PDF 182 visite)
Abstract, 2014 Feb; N/D: N/D-N/D.
Impact Factor: 0
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Lin L-L, Chen Y-Y, Chi M-C, Merlino A
* Low resolution X-ray structure of γ-glutamyltranspeptidase from Bacillus licheniformis: Opened active site cleft and a cluster of acid residues potentially involved in the recognition of a metal ion (305 visite)
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2014; 1844(9): 1523-1529.
Impact Factor: 4.882
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Avino S, D'Avino V, Giorgini A, Pacelli R, Liuzzi R, Cella L, Gagliardi G, De Natale P
* Radiation Dosimetry With Fiber Bragg Gratings (282 visite)
Proc Spie Int Soc Opt Eng (ISSN: 0277-786x, 0277-786x9781628411751), 2014; 9157: N/D-N/D.
Impact Factor: 0.958
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Alterio V, Pan P, Parkkila S, Buonanno M, Supuran CT, Monti SM, De Simone G
* The Structural Comparison Between Membrane-Associated Human Carbonic Anhydrases Provides Insights Into Drug Design Of Selective Inhibitors (377 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2014; 101(7): 769-778.
Impact Factor: 2.385
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Avino S, D'Avino V, Giorgini A, Pacelli R, Liuzzi R, Cella L, De Natale P, Gagliardi G
* Detecting ionizing radiation with optical fibers down to biomedical doses (246 visite)
Appl Phys Lettapplied Physics Letters (ISSN: 0003-6951), 2013 Oct 28; 103(18): N/D-N/D.
Impact Factor: 3.515
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Mancini M, Greco A, Salvatore G, Liuzzi R, Di Maro G, Vergara E, Chiappetta G, Pasquinelli R, Brunetti A, Salvatore M
* Imaging of thyroid tumor angiogenesis with microbubbles targeted to vascular endothelial growth factor receptor type 2 in mice (437 visite)
Bmc Med Imaging (ISSN: 1471-2342, 1471-2342electronic), 2013 Sep 12; 13(1): 31-31.
Impact Factor: 0.983
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Squeglia F, Bachert B, Romano M, Lukomski S, Berisio R
* Crystallization and preliminary X-ray crystallographic analysis of the variable domain of Scl2. 3, a streptococcal collagen-like protein from invasive M3-type Streptococcus pyogenes (343 visite)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2013 Sep; 69(9): 1023-1025.
Impact Factor: 0.568
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Squeglia F, Romano M, Ruggiero A, Vitagliano L, De Simone A, Berisio R
* Carbohydrate recognition by RpfB from mycobacterium tuberculosis unveiled by crystallographic and molecular dynamics analyses (386 visite)
Biophysical Journal (ISSN: 0006-3495, 1542-0086), 2013 Jun 4; 104(11): 2530-2539.
Impact Factor: 3.832
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Vergara A, Grassi M, Sica F, Pizzo E, D’Alessio G, Mazzarella L, Merlino A
* A Novel Interdomain Interface In Crystallins: Structural Characterization Of The Beta Gamma-Crystallin From Geodia Cydonium At 0. 99 Angstrom Resolution (379 visite)
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2013 Jun; 69(6): 960-967.
Impact Factor: 7.232
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Vergara A, D’Errico G, Montesarchio D, Mangiapia G, Paduano L, Merlino A
* Interaction of Anticancer Ruthenium Compounds with Proteins: High-Resolution X-ray Structures and Raman Microscopy Studies of the Adduct between Hen Egg White Lysozyme and AziRu (313 visite)
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 2013 Apr 15; 52(8): 4157-4159.
Impact Factor: 4.794
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Accardo A, Mangiapia G, Paduano L, Morelli G, Tesauro D
* Octreotide labeled aggregates containing platinum complexes as nanovectors for drug delivery (362 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2013 Apr; 19(4): 190-197.
Impact Factor: 1.862
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Correale S, Ruggiero A, Pedone E, Berisio R
* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of the l, d-transpeptidase LdtMt1 from Mycobacterium tuberculosis (342 visite)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2013 Mar 1; 69(3): 253-256.
Impact Factor: 0.568
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Greco A, Fiumara G, Gargiulo S, Gramanzini M, Brunetti A, Cuocolo A
* High-resolution positron emission tomography/computed tomography imaging of the mouse heart (427 visite)
Exp Physiol Experimental Physiology (ISSN: 1469-445x, 0958-0670), 2013 Mar; 98(3): 645-651.
Impact Factor: 2.871
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Camera L, Campanile F, Imbriaco M, Ippolito R, Sirignano C, Santoro C, Galderisi M, Salvatore M
* Idiopathic pulmonary fibrosis complicated by acute thromboembolic disease: Chest X-ray, HRCT and multi-detector row CT angiographic findings (258 visite) (PDF 4 visite)
J Thorac Dis (ISSN: 2072-1439), 2013 Feb; 5(1): 82-86.
Impact Factor: 0.895
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Merlino A, Fuchs MR, Pica A, Balsamo A, Dworkowski FSN, Pompidor G, Mazzarella L, Vergara A
* Selective X-ray-induced NO photodissociation in haemoglobin crystals: evidence from a Raman-assisted crystallographic study (285 visite)
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2013 Jan; 69: 137-140.
Impact Factor: 7.232
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Accardo A, Ringhieri P, Tesauro D, Morelli G
* Liposomes derivatized with tetrabranched neurotensin peptides via click chemistry reactions (362 visite)
New J Chem (ISSN: 1144-0546), 2013; 37(11): 3528-3534.
Impact Factor: 3.159
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Merlino A, Fuchs MR, Pica A, Balsamo A, Dworkowski FSN, Pompidor G, Mazzarella L, Vergara A
* Selective X-Ray Induced No-Photodissociation In Hemoglobin Crystals: Evidence From A Raman Assisted-Crystallographic Study (270 visite)
Acta Cryst D 69, 2013; 1: 137-140.
Impact Factor: 0
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Russo Krauss I, Merlino A, Randazzo A, Novellino E, Mazzarella L, Sica F
* High-resolution structures of two complexes between thrombin and thrombin-binding aptamer shed light on the role of cations in the aptamer inhibitory activity (483 visite)
Nucleic Acids Res (ISSN: 0305-1048, 1362-4962, 1362-4962electronic), 2012 Sep; 40(16): 8119-8128.
Impact Factor: 8.278
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Alterio V, Di Fiore A, D'Ambrosio K, Supuran CT, De Simone G
* Multiple binding modes of inhibitors to carbonic anhydrases: How to design specific drugs targeting 15 different isoforms? (394 visite)
Chem Rev (ISSN: 0009-2665), 2012 Sep; 112(8): 4421-4468.
Impact Factor: 41.298
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Greco A, Petretta MP, Larobina M, Gargiulo S, Panico M, Nekolla SG, Esposito G, Petretta M, Brunetti A, Cuocolo A
* Reproducibility and accuracy of non-invasive measurement of infarct size in mice with high-resolution PET/CT (365 visite)
J Nucl Cardiol (ISSN: 1532-6551, 1071-3581, 1532-6551electronic), 2012 Jun; 19(3): 492-499.
Impact Factor: 2.847
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Maglione M, Bush A, Montella S, Mollica C, Manna A, Esposito A, Santamaria F
* Progression of lung disease in primary ciliary dyskinesia: Is spirometry less accurate than CT? (341 visite)
Pediatr Pulmonol (ISSN: 8755-6863), 2012 May; 47(5): 498-504.
Impact Factor: 2.375
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Esposito L, Ruggiero A, Masullo M, Ruocco MR, Lamberti A, Arcari P, Zagari A, Vitagliano L
* Crystallographic and spectroscopic characterizations of Sulfolobus solfataricus TrxA1 provide insights into the determinants of thioredoxin fold stability (283 visite)
J Struct Biol (ISSN: 1047-8477), 2012 Feb; 177(2): 506-512.
Impact Factor: 3.361
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Montella S, Maglione M, Bruzzese D, Mollica C, Pignata C, Aloj G, Manna A, Esposito A, Mirra V, Santamaria F
* Magnetic resonance imaging is an accurate and reliable method to evaluate non-cystic fibrosis paediatric lung disease (295 visite)
Respirology (ISSN: 1323-7799, 1440-1843electronic), 2012 Jan; 17(1): 87-91.
Impact Factor: 2.781
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Accardo A, Salsano G, Morisco A, Aurilio M, Parisi A, Maione F, Cicala C, Tesauro D, Aloj L, De Rosa G, Morelli G
* Peptide-modified liposomes for selective targeting of bombesin receptors overexpressed by cancer cells: A potential theranostic agent (338 visite)
Int J Nanomed (ISSN: 1176-9114, 1178-2013, 1178-2013electronic), 2012; 7: 2007-2017.
Impact Factor: 3.463
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Ruggiero A, Dattelbaum JD, Pennacchio A, Iozzino L, Staiano M, Luchansky MS, Der BS, Berisio R, D'Auria S, Vitagliano L
* Crystallization and preliminary X-ray crystallographic analysis of ligand-free and arginine-bound forms of Thermotoga maritima arginine-binding protein (342 visite)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2011 Nov 1; 67(11): 1462-1465.
Impact Factor: 0.506
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Malgieri G, Zaccaro L, Leone M, Bucci E, Esposito S, Baglivo I, Del Gatto A, Russo L, Scandurra R, Pedone PV, Fattorusso R, Isernia C
* Zinc to Cadmium Replacement in the A. thaliana SUPERMAN Cys(2)His(2) Zinc Finger Induces Structural Rearrangements of Typical DNA Base Determinant Positions (381 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2011 Nov; 95(11): 801-810.
Impact Factor: 2.87
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Accardo A, Morisco A, Tesauro D, Pedone C, Morelli G
* Naposomes: A new class of peptide-derivatized, target-selective multimodal nanoparticles for imaging and therapeutic applications (387 visite)
Ther Deliv (ISSN: 2041-5990), 2011 Feb; 2(2): 235-257.
Impact Factor: 0
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Ruggiero A, Squeglia F, Pirone L, Correale S, Berisio R
* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a major fragment of the resuscitation-promoting factor RpfB from Mycobacterium tuberculosis (356 visite)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2011 Jan 1; 67(1): 164-168.
Impact Factor: 0.506
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Di Fiore A, Maresca A, Alterio V, Supuran CT, De Simone G
* Carbonic anhydrase inhibitors: X-ray crystallographic studies for the binding of N-substituted benzenesulfonamides to human isoform II (324 visite)
Chem Commun (ISSN: 1359-7345, 1364-548x, 1364-548xelectronic), 2011; 47(42): 11636-11638.
Impact Factor: 6.169
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Ruggiero A, Squeglia F, Izzo V, Silipo A, Vitagliano L, Molinaro A, Berisio R
* Expression, purification, crystallization and preliminary x-ray crystallographic analysis of the peptidoglycan binding region of the ser/thr kinase PrkC from staphylococcus aureus (335 visite)
Protein Pept Lett (ISSN: 0929-8665, 1875-5305), 2010 Oct; 17(10): 1296-1299.
Impact Factor: 1.849
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Ferro A, Greco A, Gargiulo S, Larobina M, Petretta MP, Esposito G, Panico M, Nekolla SG, Brunetti A, Cuocolo A
* Reproducibility of Quantitative Measurement of Infarct Size in Mice With High-Resolution PET/CT Imaging (324 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2010 Oct; 37: N/D-N/D.
Impact Factor: 5.036
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Alterio V, Monti SM, Truppo E, Pedone C, Supuran CT, De Simone G
* The first example of a significant active site conformational rearrangement in a carbonic anhydrase-inhibitor adduct: The carbonic anhydrase I-topiramate complex (380 visite)
Org Biomol Chem (ISSN: 1477-0520, 1477-0539, 1477-0539electronic), 2010 Sep 7; 8(15): 3528-3533.
Impact Factor: 3.451
Dettagli Esporta in BibTeX Esporta in EndNote
Di Fiore A, Monti SM, Innocenti A, Winum J-Y, De Simone G, Supuran CT
* Carbonic anhydrase inhibitors: Crystallographic and solution binding studies for the interaction of a boron-containing aromatic sulfamide with mammalian isoforms I-XV (320 visite)
Bioorg Med Chem Lett Bioorganic And Medicinal Chemistry Letters (ISSN: 0960-894x), 2010 Jun 15; 20(12): 3601-3605.
Impact Factor: 2.661
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Diana D, Ziaco B, Scarabelli G, Pedone C, Colombo G, D'Andrea LD, Fattorusso R
* Structural analysis of a helical peptide unfolding pathway (404 visite)
Chemistry (ISSN: 1521-3765, 0947-6539, 1521-3765electronic), 2010 May 10; 16(18): 5400-5407.
Impact Factor: 5.476
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De Simone G, Supuran CT
* Carbonic anhydrase IX: Biochemical and crystallographic characterization of a novel antitumor target (362 visite)
Bba-Gen Subjects (ISSN: 1570-9639, 0006-3002, 0925-4439), 2010 Feb; 1804(2): 404-409.
Impact Factor: 2.773
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Ruggiero A, Squeglia F, Esposito C, Marasco D, Pedone E, Pedone C, Berisio R
* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of the resuscitation promoting factor interacting protein RipA from M. tuberculosis (323 visite)
Protein Pept Lett (ISSN: 0929-8665, 1875-5305), 2010 Jan; 17(1): 70-73.
Impact Factor: 1.849
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Merlino A, Vitagliano L, Howes BD, Verde C, Di Prisco G, Smulevich G, Sica F, Vergara A
* Combined Crystallographic and Spectroscopic Analysis of Trematomus bernacchii Hemoglobin Highlights Analogies and Differences in the Peculiar Oxidation Pathway of Antarctic Fish Hemoglobins (368 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2009 Dec; 91(12): 1117-1125.
Impact Factor: 2.605
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Vitagliano L, Stanzione F, De Simone A, Esposito L
* Dynamics and Stability of Amyloid-Like Steric Zipper Assemblies with Hydrophobic Dry Interfaces (379 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2009 Dec; 91(12): 1161-1171.
Impact Factor: 2.605
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Varrone A, Sjoholm N, Eriksson L, Gulyas B, Halldin C, Farde L
* Advancement in PET quantification using 3D-OP-OSEM point spread function reconstruction with the HRRT (348 visite) (PDF 248 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2009 Oct; 36(10): 1639-1650.
Impact Factor: 4.531
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Moccia M, Musumeci D, Roviello GN, Fusco S, Valente M, Bucci EM, Sapio R, Pedonea C, Netti PA
* Preliminary studies on noncovalent hyperbranched polymers based on PNA and DNA building blocks (590 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Oct; 15(10): 647-653.
Impact Factor: 1.807
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Montella S, Santamaria F, Salvatore M, Maglione M, Iacotucci P, De Santi MM, Mollica C
* Lung disease assessment in primary ciliary dyskinesia: a comparison between chest high-field magnetic resonance imaging and high-resolution computed tomography findings (367 visite)
Ital J Pediatr (ISSN: 1824-7288, 1720-8424), 2009 Sep 6; 35(24): 24-24.
Impact Factor: 0.722
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Montella S, Santamaria F, Salvatore M, Pignata C, Maglione M, Iacotucci P, Mollica C
* Assessment of chest high-field magnetic resonance imaging in children and young adults with noncystic fibrosis chronic lung disease: comparison to high-resolution computed tomography and correlation with pulmonary function (219 visite)
Invest Radiol (ISSN: 1536-0210, 0020-9996, 1536-0210electronic), 2009 Sep; 44(9): 532-538.
Impact Factor: 4.85
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Ruggiero A, Lanzotti MA, Ruocco MR, Grimaldi P, Marasco D, Arcari P, Masullo M, Zagari A, Vitagliano L
* Crystallization and preliminary X-ray crystallographic analysis of two dimeric hyperthermostable thioredoxins isolated from Sulfolobus solfataricus (306 visite)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2009 Jun; 65: 604-607.
Impact Factor: 0.551
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Vitagliano L, Vergara A, Bonomi G, Merlino A, Verde C, Di Prisco G, Howes BD, Smulevich G, Mazzarella L
* Spectroscopic and crystallographic characterization of a tetrameric hemoglobin oxidation reveals structural features of the functional intermediate relaxed/tense state (363 visite)
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126), 2008 Sep 13; 130(32): 10527-10535.
Impact Factor: 8.091
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Ruggiero A, Chambery A, Di Maro A, Parente A, Berisio R
* Atomic Resolution (1. 1 Angstrom) Structure Of The Ribosome-Inactivating Protein Pd-L4 From Phytolacca Dioica L. Leaves (350 visite)
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2008 Apr; 71(1): 8-15.
Impact Factor: 3.419
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Licciardello MP, D'Agata R, Grasso G, Simone S, Spoto G
* Atmospheric Pressure Laser Desorption Mass Spectrometry based methods for the study of traditional painting materials (208 visite)
Lasers Conserv Artworks Proc Int Conf Lacona Vii (ISSN: 9780-4154), 2008; N/D: 67-72.
Impact Factor: 0
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Vitagliano L, Vergara A, Bonomi G, Merlino A, Verde C, Di Prisco G, Howes BD, Smulevich G, Mazzarella L
* Spectroscopic And Crystallographic Characterization Of A Tetrameric Hemoglobin Oxidation Pathway Reveals Structural Features Of A Functional Intermediate R/T State (261 visite)
Biophys J, 2008; 94: 4031-4040.
Impact Factor: 3.832
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Vergara A, Vitagliano L, Verde C, di Prisco G, Mazzarella L
* Spectroscopic and crystallographic characterization of bis-histidyl adducts in tetrameric hemoglobins (383 visite)
Method Enzymol (ISSN: 0076-6879, 1557-7988electronic), 2008; 436: 425-444.
Impact Factor: 2.312
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Vergara A, Vitagliano L, Di Prisco G, Verde C, Mazzarella L
* Spectroscopic And Crystallographic Characterization Of Hemichromes In Tetrameric Hemoglobins (303 visite)
Methods In Enzymology, 2008; 436: 421-440.
Impact Factor: 2.194
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Ruggiero A, Tizzano B, Geerlof A, Pedone E, Pedone C, Wilmanns M, Berisio R
* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a resuscitation-promoting factor from Mycobacterium tuberculosis (352 visite)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2007 Oct 1; 63(10): 870-873.
Impact Factor: 0.645
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Alterio V, De Simone G, Monti SM, Scozzafava A, Supuran CT
* Carbonic anhydrase inhibitors: Inhibition of human, bacterial, and archaeal isozymes with benzene-1, 3-disulfonamides-Solution and crystallographic studies (307 visite)
Bioorg Med Chem Lett Bioorganic And Medicinal Chemistry Letters (ISSN: 0960-894x), 2007 Sep 1; 17(15): 4201-4207.
Impact Factor: 2.604
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Cusanno F, Cisbani E, Colilli S, Fratoni R, Garibaldi F, Giuliani F, Gricia M, Lucentini M, Magliozzi ML, Santarivenere F, Torrioli S, Cinti MN, Pani R, Pellegrini R, Simonetti G, Schillaci O, Del Vecchio S, Salvatore M, Majewski S, De Vincentis G, Scopinaro F
* Results of clinical trials with SPEM (248 visite)
Nucl Instrum Methods Phys Res Sect A, 2007 Feb 1; 497(1): 46-50.
Impact Factor: 3.221
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Aloj L, Aurilio M, Rinaldi V, D'Ambrosio L, Tesauro D, Peitl PK, Maina T, Mansi R, Von Guggenberg E, Joosten L, Sosabowski JK, Breeman WA, De Blois E, Koelewijn S, Melis M, Waser B, Beetschen K, Reubi JC, De Jong M
* The EEE project (431 visite)
Proc Int Cosm Ray Conf Icrc Universidad Nacional Autonoma De Mexico, 2007; 5(HEPART2): 977-980.
Impact Factor: 0
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Garibaldi F, Cisbani E, Colilli S, Cusanno F, Fratoni R, Giuliani F, Gricia M, Lucentini M, Fratoni R, Lo Meo S, Magliozzi ML, Santanvenere F, Cinti MN, Pani R, Pellegrini R, Simonetti G, Schillaci O, Del Vecchio S, Salvatore M, Majewski S, Lanza RC, De Vincentis G, Scopinaro F
* Molecular imaging: High-resolution detectors for early diagnosis and therapy monitoring of breast cancer (313 visite)
Nucl Instrum Meth A (ISSN: 0168-9002), 2006 Dec 20; 569(2SPEC.ISS.): 286-290.
Impact Factor: 1.185
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Menchise V, De Simone G, Di Fiore A, Scozzafava A, Supuran CT
* Carbonic anhydrase inhibitors: X-ray crystallographic studies for the binding of 5-amino-1, 3, 4-thiadiazole-2-sulfonamide and 5-(4-amino-3-chloro-5-fluorophenylsulfonamido)1, 3, 4-thiadiazole-2-sulfon amide to human isoform II (285 visite)
Bioorganic & Medicinal Chemistry Letters (ISSN: 0960-894x), 2006 Dec 15; 16(24): 6204-6208.
Impact Factor: 2.538
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Mazzarella L, Vergara A, Vitagliano L, Merlino A, Bonomi G, Scala S, Verde C, Di Prisco G
* High resolution crystal structure of deoxy hemoglobin from Trematomus bernacchii at different pH values: The role of histidine residues in modulating the strength of the root effect (354 visite)
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2006 Nov 1; 65(2): 490-498.
Impact Factor: 3.73
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Santamaria F, Montella S, Camera L, Palumbo C, Greco L, Boner AL
* Lung structure abnormalities, but normal lung function in pediatric bronchiectasis (373 visite)
Chest (ISSN: 0012-3692), 2006 Sep; 130(2): 480-486.
Impact Factor: 3.924
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Ruggiero A, Masullo M, Arcari P, Raimo G, Vitagliano L, Zagari A
* Crystallization And Preliminary X-Ray Crystallographic Analysis Of The Sulfolobus Solfataricus Nucleotide-Exchange Factor 1 Beta (312 visite)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2005 Nov; 61(11): 1000-1002.
Impact Factor: 0.568
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Ruggiero A, Ruocco MR, Grimaldi P, Arcari P, Masullo M, Zagari A, Vitagliano L
* Crystallization and preliminary X-ray crystallographic analysis of Sulfolobus solfataricus thioredoxin reductase (297 visite)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2005 Oct; 61: 906-909.
Impact Factor: 0.568
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De Simone G, Di Fiore A, Menchise V, Pedone C, Antel J, Casini A, Scozzafava A, Wurl M, Supuran CT
* Carbonic anhydrase inhibitors. Zonisamide is an effective inhibitor of the cytosolic isozyme II and mitochondrial isozyme V: solution and X-ray crystallographic studies (324 visite)
Bioorg Med Chem Lett Bioorganic And Medicinal Chemistry Letters (ISSN: 0960-894x), 2005 May 2; 15(9): 2315-2320.
Impact Factor: 2.478
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Galdiero S, Gouaux E
* High Resolution Crystallographic Studies Of Alpha-Hemolysin-Phospholipid Complexes Define Heptamer-Lipid Head Group Interactions: Implication For Understanding Protein-Lipid Interactions (302 visite)
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic), 2004 Jun; 13(6): 1503-1511.
Impact Factor: 4.116
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De Simone G, Menchise V, Omaggio S, Pedone C, Scozzafava A, Supuran CT
* Design of weakly basic thrombin inhibitors incorporating novel P1 binding functions: Molecular and X-ray crystallographic studies (324 visite)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2003 Sep 5; 42(30): 9013-9021.
Impact Factor: 3.922
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Esposito L, Sica F, Raia CA, Giordano A, Rossi M, Mazzarella L, Zagari A
* Crystal Structure Of The Alcohol Dehydrogenase From The Hyperthermophilic Archaeon Sulfolobus Solfataricus At 1. 85 Angstrom Resolution (390 visite)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2002 Apr 26; 318(2): 463-477.
Impact Factor: 5.359
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Esposito L, Vitagliano L, Mazzarella L
* Recent advances in atomic resolution protein crystallography (340 visite)
Protein Pept Lett (ISSN: 0929-8665, 1875-5305), 2002 Apr; 9(2): 95-105.
Impact Factor: 0.622
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Berisio R, Sica F, Lamzin VS, Wilson KS, Zagari A, Mazzarella L
* Atomic resolution structures of ribonuclease A at six pH values (459 visite)
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2002; 58(3): 441-450.
Impact Factor: 1.76
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Berisio R, Sica F, Lamzin VS, Wilson KS, Zagari A, Mazzarella L
* Atomic Resolution Structures Of Rnase A At Six Ph Values (217 visite)
Acta Crystallogr D Biol Crystallogr, 2002; N/D: 441-450.
Impact Factor: 7.232
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Celentano L, Laccetti P, Liuzzi R, Mettivier G, Montesi MC, Autiero M, Riccio P, Roberti G, Russo P, Salvatore M
* Preliminary tests of a prototype system for optical and radionuclide imaging in small animals (304 visite)
Ieee Nuclear Science Symposium And Medical Imaging Conference, 2002; 3: 1746-1750.
Impact Factor: 0
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De Simone G, Menchise V, Manco G, Mandrich L, Sorrentino N, Lang D, Rossi M, Pedone C
* The crystal structure of a hyper-thermophilic carboxylesterase from the archaeon Archaeoglobus fulgidus (339 visite)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2001 Nov 30; 314(3): 507-518.
Impact Factor: 5.826
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Berisio R, Viguera A, Serrano L, Wilmanns M
* Atomic resolution structure of a mutant of the spectrin SH3 domain (268 visite)
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2001 Feb; 57(2): 337-340.
Impact Factor: 2.124
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Esposito L, Vitagliano L, Zagari A, Mazzarella L
Experimental evidence for the correlation of bond distances in peptide groups detected in ultrahigh-resolution protein structures (266 visite)
Protein Eng (ISSN: 0269-2139, 0269-2139print, 0269-2139linking), 2000 Dec; 13(12): 825-828.
Impact Factor: 2.442
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Esposito L, Vitagliano L, Zagari A, Mazzarella L
Pyramidalization of backbone carbonyl carbon atoms in proteins (402 visite)
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic), 2000 Oct; 9(10): 2038-2042.
Impact Factor: 3.869
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Esposito L, Vitagliano L, Sica F, Sorrentino G, Zagari A, Mazzarella L
The ultrahigh resolution crystal structure of ribonuclease A containing an isoaspartyl residue: Hydration and sterochemical analysis (408 visite)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2000 Mar 31; 297(3): 713-732.
Impact Factor: 5.388
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Berisio R, Vitagliano L, Mazzarella L, Zagari A
Crystal Structure Of A Collagen-Like Polypeptide With Repeating Sequence Pro-Hyp-Gly At 1. 4 Ang Resolution: Implications For Collagen Hydration (396 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2000; 56(1): 8-13.
Impact Factor: 2.405
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Berisio R, Lamzin VS, Sica F, Wilson KS, Zagari A, Mazzarella L
Protein titration in the crystal state (357 visite)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 1999 Oct 1; 292(4): 845-854.
Impact Factor: 5.501
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Kramer RZ, Vitagliano L, Bella J, Berisio R, Mazzarella L, Brodsky B, Zagari A, Berman HM
X-ray crystallographic determination of a collagen-like peptide with the repeating sequence (Pro-Pro-Gly) (376 visite)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 1998 Jul 24; 280(4): 623-638.
Impact Factor: 5.803
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Zanotti G, Saviano M, Saviano G, Tancredi T, Rossi F, Pedone C, Benedetti E
Structure of cyclic peptides: the crystal and solution conformation of cyclo(Phe-Phe-Aib-Leu-Pro) (398 visite)
Journal Of Peptide Research (ISSN: 1397-002x), 1998 Jun; 51(6): 460-466.
Impact Factor: 1.125
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Crisma M, Formaggio F, Valle G, Toniolo C, Saviano M, Iacovino R, Zaccaro L, Benedetti E
Experimental evidence at atomic resolution for intramolecular N- H···π (phenyl) interactions in a family of amino acid derivatives (378 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1997; 42(1): 1-6.
Impact Factor: 2.425
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Soricelli A, Mainenti PP, Leone D, Discepolo A, Romano M, Varrone A, Servillo G, Serio S, Brunetti A, Salvatore M
Evaluation of brain perfusion with high resolution single photon emission tomography in the diagnosis of brain death (222 visite)
Minerva Anestesiol (ISSN: 0375-9393), 1996 Jun; 62(6): 209-212.
Impact Factor: 1.627
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Cucinotta V, Grasso G, Pedotti S, Rizzarelli E, Vecchio G, Di Blasio B, Isernia C, Saviano M, Pedone C
A Platinum(II) Diamino-β-cyclodextrin Complex: A Crystallographic and Solution Study. Synthesis and Structural Characterization of a Platinum(II) Complex of 6A, 6B-Diamino-6A, 6B-dideoxycyclomaltoheptaose (265 visite)
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 1996; 35(26): 7535-7540.
Impact Factor: 2.736
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Bonomo RP, De Flora A, Rizzarelli E, Santoro AM, Tabbì G, Tonetti M
Copper(II) complexes encapsulated in human red blood cells (558 visite)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 1995 Sep; 59(4): 773-784.
Impact Factor: 1.342
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Ferrara LA, Mancini M, Celentano A, Galderisi M, Iannuzzi R, Marotta T, Gaeta I
Early changes of the arterial carotid wall in uncomplicated primary hypertensive patients: Study by ultrasound high-resolution B-mode imaging (252 visite)
Arterioscler Thromb Vasc Biol Arteriosclerosis Thrombosis And Vascular Biology (ISSN: 1079-5642, 1049-8834), 1994 Sep; 14(8): 1290-1296.
Impact Factor: 5.317
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Alfano B, Bandettini A, Bencivelli W, Bertolucci E, Bottigli U, Conti M, Del Guerra A, Fantacci ME, Gambaccini M, Larobina M, Marziani M, Randaccio P, Rosso V, Russo P, Stefanini A
Digital imaging in radiology: preliminary results obtained with a high spatial resolution 2D silicon detector (285 visite)
Ieee Transactions On Nuclear Science (ISSN: 0018-9499), 1993 Sep; 40(4pt1): 987-991.
Impact Factor: 1.048
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107 Records (101 escludendo Abstract e Conferenze).
Impact factor totale: 357.84 (348.33 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 374.245 (365.437 escludendo Abstract e Conferenze).
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Alterio V, Langella E, Buonanno M, Esposito D, Nocentini A, Berrino E, Bua S, Polentarutti M, Supuran CT, Monti SM, De Simone G
* Zeta-carbonic anhydrases show CS(2) hydrolase activity: A new metabolic carbon acquisition pathway in diatoms? (5 visite)
Comput Struct Biotechnol J (ISSN: 2001-0370linking), 2021 Jun 5; 19: 3427-3436.
Impact Factor: 7.271
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Wang L, Bateman B, Zanetti-domingues L, Moores A, L , Astbury S, Spindloe C, Darrow M, C , Romano M, Needham S, R , Beis K, Rolfe D, J , Clarke D, T , Martin-fernandez M, L
Solid immersion microscopy images cells under cryogenic conditions with 12 nm resolution (70 visite)
Commun Biol, 2019 Feb 21; 2:74: N/D-N/D.
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Barbuto L, Di Serafino M, Della Vecchia N, Rea G, Esposito F, Vezzali N, Ferro F, Caprio MG, Vola EA, Romeo V, Vallone G
* Pediatric musculoskeletal ultrasound: a pictorial essay (147 visite) (PDF 78 visite)
J Ultrasound (ISSN: 1876-7931linking, 1876-7931electronic), 2018 Nov 9; N/D: N/D-N/D.
Impact Factor: 1.53
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Squeglia F, Berisio R, Ruggiero A
* The novel thermostable cellulose-degrading enzyme DtCel5H from Dictyoglomus thermophilum: crystallization and X-ray crystallographic analysis (314 visite)
Acta Crystallogr F Struct Biol Commun (ISSN: 2053-230xelectronic, 2053-230xlinking), 2018 Jan 1; 74(Pt1): 1-5.
Impact Factor: 0.8
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De Simone G, Langella E, Esposito D, Supuran CT, Monti SM, Winum JY, Alterio V
* Insights into the binding mode of sulphamates and sulphamides to hCA II: crystallographic studies and binding free energy calculations (227 visite)
J Enzym Inhib Med Ch (ISSN: 1475-6366, 1475-6374electronic, 1475-6366linking), 2017 Dec; 32(1): 1002-1011.
Impact Factor: 3.638
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Sgarlata C, Mugridge JS, Pluth MD, Zito V, Arena G, Raymond KN
* Different and Often Opposing Forces Drive the Encapsulation and Multiple Exterior Binding of Charged Guests to a M4 L6 Supramolecular Vessel in Water (236 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2017 Nov 27; 23(66): 16813-16818.
Impact Factor: 5.16
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Galati C, Spinella N, Renna L, Milardi D, Attanasio F, Sciacca MFM, Bongiorno C
* Strategy to discover full-length amyloid-beta peptide ligands using high-efficiency microarray technology (388 visite)
Beilstein J Nanotech (ISSN: 2190-4286), 2017 Nov 20; 8(1): 2446-2453.
Impact Factor: 2.968
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Vullo D, Supuran CT, Scozzafava A, De Simone G, Monti SM, Alterio V, Carta F
* Kinetic and X-ray crystallographic investigations of substituted 2-thio-6-oxo-1, 6-dihydropyrimidine-benzenesulfonamides acting as carbonic anhydrase inhibitors (231 visite)
Bioorg Med Chem (ISSN: 0968-0896, 1464-3391), 2016 Aug 15; 24(16): 3643-3648.
Impact Factor: 2.93
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Di Fiore A, De Simone G, Alterio V, Riccio V, Winum JY, Carta F, Supuran CT
* The anticonvulsant sulfamide JNJ-26990990 and its S, S-dioxide analog strongly inhibit carbonic anhydrases: solution and X-ray crystallographic studies (218 visite)
Org Biomol Chem (ISSN: 1477-0520, 1477-0539, 1477-0539electronic), 2016 Jun 07; 14(21): 4853-4858.
Impact Factor: 3.564
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Langella E, D'Ambrosio K, D'Ascenzio M, Carradori S, Monti SM, Supuran CT, De Simone G
* A Combined Crystallographic and Theoretical Study Explains the Capability of Carboxylic Acids to Adopt Multiple Binding Modes in the Active Site of Carbonic Anhydrases (300 visite)
Chemistry (ISSN: 0947-6539, 1521-3765, 1521-3765electronic), 2016 Jan 4; 22(1): 97-100.
Impact Factor: 5.317
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Ringhieri P, Avitabile C, Saviano M, Morelli G, Romanelli A, Accardo A
* The influence of liposomal formulation on the incorporation and retention of PNA oligomers (156 visite)
Colloid Surface B (ISSN: 0927-7765), 2016; 145: 462-469.
Impact Factor: 3.887
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Borrelli P, Palma G, Tedeschi E, Cocozza S, Comerci M, Alfano B, Haacke EM, Salvatore M
* Improving Signal-to-Noise Ratio in Susceptibility Weighted Imaging: A Novel Multicomponent Non-Local Approach (416 visite) (PDF 230 visite)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2015 Jun 1; 10(6): e0126835-e0126835.
Impact Factor: 3.057
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Scotto di Santolo M, Sagnelli M, Mancini M, Scalvenzi M, Delfino M, Schonauer F, Molea G, Ayala F, Salvatore M
* Erratum to: High-resolution color-Doppler ultrasound for the study of skin growths (254 visite)
Arch Dermatol Res (ISSN: 0340-3696), 2015 Apr 7; Epub: N/D-N/D.
Impact Factor: 2.146
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Alterio V, Tanc M, Ivanova J, Zalubovskis R, Vozny I, Monti SM, Di Fiore A, De Simone G, Supuran CT
* X-ray crystallographic and kinetic investigations of 6-sulfamoyl-saccharin as a carbonic anhydrase inhibitor (316 visite)
Org Biomol Chem (ISSN: 1477-0520, 1477-0539, 1477-0539electronic), 2015 Apr 7; 13(13): 4064-4069.
Impact Factor: 3.559
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Avino S, D'Avino V, Giorgini A, Pacelli R, Liuzzi R, Cella L, De Natale P, Gagliardi G
* Ionizing radiation detectors based on ge-doped optical fibers inserted in resonant cavities (291 visite)
Sensors (ISSN: 1424-8220, 1424-3210, 1424-8220linking), 2015 Feb 12; 15(2): 4242-4252.
Impact Factor: 2.033
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Scotto di Santolo M, Sagnelli M, Mancini M, Scalvenzi M, Delfino M, Schonauer F, Molea G, Ayala F, Salvatore M
* High-resolution color-Doppler ultrasound for the study of skin growths (283 visite)
Arch Dermatol Res (ISSN: 0340-3696), 2015 Jan 21; Epub: N/D-N/D.
Impact Factor: 2.146
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Troise AD, Fiore A, Roviello GN, Monti SM, Fogliano V
* Simultaneous quantification of amino acids and Amadori products in foods through ion-pairing liquid chromatography-high-resolution mass spectrometry (808 visite)
Amino Acids (ISSN: 0939-4451, 1438-2199, 1438-2199electronic), 2015 Jan; 47(1): 111-124.
Impact Factor: 3.196
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Nardon C, Boscutti G, Dalla Via L, Ringhieri P, Di Noto V, Morelli G, Accardo A, Fregona D
* CCK8 peptide-labeled Pluronic® F127 micelles as a targeted vehicle of gold-based anticancer chemotherapeutics (356 visite)
Medchemcomm (ISSN: 2040-2503), 2015; 6(1): 155-163.
Impact Factor: 2.319
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Avitabile C, Accardo A, Ringhieri P, Morelli G, Saviano M, Montagner G, Fabbri E, Gallerani E, Gambari R, Romanelli A
* Incorporation of Naked Peptide Nucleic Acids into Liposomes Leads to Fast and Efficient Delivery (411 visite)
Bioconjug Chem (ISSN: 1043-1802, 1520-4812), 2015; 26(8): 1533-1541.
Impact Factor: 4.5
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Mügge C, Marzo T, Massai L, Hildebrandt J, Ferraro G, Rivera-Fuentes P, Metzler-Nolte N, Merlino A, Messori L, Weigand W
* Platinum(II) Complexes with O, S Bidentate Ligands: Biophysical Characterization, Antiproliferative Activity, and Crystallographic Evidence of Protein Binding (300 visite)
Inorg Chem (ISSN: 0020-1669, 1520-510x, 0020-1669linking), 2015; 54(17): 8560-8570.
Impact Factor: 4.82
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Ringhieri P, Iannitti R, Nardon C, Palumbo R, Fregona D, Morelli G, Accardo A
* Target selective micelles for bombesin receptors incorporating Au(III)-dithiocarbamato complexes (359 visite)
Int J Pharm (ISSN: 0378-5173, 1873-3476), 2014 Oct 1; 473(1-2): 194-202.
Impact Factor: 3.65
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Merlino A, Vergara A, Vitagliano L
* Comments on Structural studies of haemoglobin from pisces species shortfin mako shark (Isurus oxyrinchus) at 1. 9 angstrom resolution by P. Ramesh et al. (2013). J. Synchrotron Rad. 20, 843-847 (255 visite)
J Synchrotron Radiat (ISSN: 0909-0495), 2014 Jul; 21: N/D-N/D.
Impact Factor: 2.794
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Santamaria F, Esposito M, Montella S, Cantone E, Mollica C, De Stefano S, Mirra V, Carotenuto M
* Sleep disordered breathing and airway disease in primary ciliary dyskinesia (450 visite)
Respirology (ISSN: 1323-7799, 1440-1843electronic), 2014 May; 19(4): 570-575.
Impact Factor: 3.345
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Accardo A, Aloj L, Aurilio M, Morelli G, Tesauro D
* Receptor binding peptides for target-selective delivery of nanoparticles encapsulated drugs (514 visite)
Int J Nanomed (ISSN: 1178-2013, 1176-9114, 1176-9114linking), 2014 Mar 27; 9(1): 1537-1557.
Impact Factor: 4.383
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Squeglia F, Bachert B, De Simone A, Lukomski S, Berisio R
* The crystal structure of the streptococcal collagen-like protein 2 globular domain from invasive M3-type group a streptococcus shows significant similarity to immunomodulatory HIV protein gp41 (371 visite)
Jbc Papers (ISSN: 0021-9258, 1083-351x, 0021-9258linking), 2014 Feb 21; 289(8): 5122-5133.
Impact Factor: 4.573
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Mancini M, Palma G, Tedeschi E, Greco A, Ragucci M
* Extracranial Brain Draining Veins In Mouse: Assessment By High Resolution Ultrasound And Mr Angiography Of The Neck (242 visite) (PDF 182 visite)
Abstract, 2014 Feb; N/D: N/D-N/D.
Impact Factor: 0
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Lin L-L, Chen Y-Y, Chi M-C, Merlino A
* Low resolution X-ray structure of γ-glutamyltranspeptidase from Bacillus licheniformis: Opened active site cleft and a cluster of acid residues potentially involved in the recognition of a metal ion (305 visite)
Bba-Gen Subjects (ISSN: 0925-4439, 0006-3002, 1570-9639), 2014; 1844(9): 1523-1529.
Impact Factor: 4.882
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Avino S, D'Avino V, Giorgini A, Pacelli R, Liuzzi R, Cella L, Gagliardi G, De Natale P
* Radiation Dosimetry With Fiber Bragg Gratings (282 visite)
Proc Spie Int Soc Opt Eng (ISSN: 0277-786x, 0277-786x9781628411751), 2014; 9157: N/D-N/D.
Impact Factor: 0.958
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Alterio V, Pan P, Parkkila S, Buonanno M, Supuran CT, Monti SM, De Simone G
* The Structural Comparison Between Membrane-Associated Human Carbonic Anhydrases Provides Insights Into Drug Design Of Selective Inhibitors (377 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2014; 101(7): 769-778.
Impact Factor: 2.385
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Avino S, D'Avino V, Giorgini A, Pacelli R, Liuzzi R, Cella L, De Natale P, Gagliardi G
* Detecting ionizing radiation with optical fibers down to biomedical doses (246 visite)
Appl Phys Lettapplied Physics Letters (ISSN: 0003-6951), 2013 Oct 28; 103(18): N/D-N/D.
Impact Factor: 3.515
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Mancini M, Greco A, Salvatore G, Liuzzi R, Di Maro G, Vergara E, Chiappetta G, Pasquinelli R, Brunetti A, Salvatore M
* Imaging of thyroid tumor angiogenesis with microbubbles targeted to vascular endothelial growth factor receptor type 2 in mice (437 visite)
Bmc Med Imaging (ISSN: 1471-2342, 1471-2342electronic), 2013 Sep 12; 13(1): 31-31.
Impact Factor: 0.983
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Squeglia F, Bachert B, Romano M, Lukomski S, Berisio R
* Crystallization and preliminary X-ray crystallographic analysis of the variable domain of Scl2. 3, a streptococcal collagen-like protein from invasive M3-type Streptococcus pyogenes (343 visite)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2013 Sep; 69(9): 1023-1025.
Impact Factor: 0.568
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Squeglia F, Romano M, Ruggiero A, Vitagliano L, De Simone A, Berisio R
* Carbohydrate recognition by RpfB from mycobacterium tuberculosis unveiled by crystallographic and molecular dynamics analyses (386 visite)
Biophysical Journal (ISSN: 0006-3495, 1542-0086), 2013 Jun 4; 104(11): 2530-2539.
Impact Factor: 3.832
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Vergara A, Grassi M, Sica F, Pizzo E, D’Alessio G, Mazzarella L, Merlino A
* A Novel Interdomain Interface In Crystallins: Structural Characterization Of The Beta Gamma-Crystallin From Geodia Cydonium At 0. 99 Angstrom Resolution (379 visite)
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2013 Jun; 69(6): 960-967.
Impact Factor: 7.232
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Vergara A, D’Errico G, Montesarchio D, Mangiapia G, Paduano L, Merlino A
* Interaction of Anticancer Ruthenium Compounds with Proteins: High-Resolution X-ray Structures and Raman Microscopy Studies of the Adduct between Hen Egg White Lysozyme and AziRu (313 visite)
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 2013 Apr 15; 52(8): 4157-4159.
Impact Factor: 4.794
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Accardo A, Mangiapia G, Paduano L, Morelli G, Tesauro D
* Octreotide labeled aggregates containing platinum complexes as nanovectors for drug delivery (362 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2013 Apr; 19(4): 190-197.
Impact Factor: 1.862
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Correale S, Ruggiero A, Pedone E, Berisio R
* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of the l, d-transpeptidase LdtMt1 from Mycobacterium tuberculosis (342 visite)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2013 Mar 1; 69(3): 253-256.
Impact Factor: 0.568
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Greco A, Fiumara G, Gargiulo S, Gramanzini M, Brunetti A, Cuocolo A
* High-resolution positron emission tomography/computed tomography imaging of the mouse heart (427 visite)
Exp Physiol Experimental Physiology (ISSN: 1469-445x, 0958-0670), 2013 Mar; 98(3): 645-651.
Impact Factor: 2.871
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Camera L, Campanile F, Imbriaco M, Ippolito R, Sirignano C, Santoro C, Galderisi M, Salvatore M
* Idiopathic pulmonary fibrosis complicated by acute thromboembolic disease: Chest X-ray, HRCT and multi-detector row CT angiographic findings (258 visite) (PDF 4 visite)
J Thorac Dis (ISSN: 2072-1439), 2013 Feb; 5(1): 82-86.
Impact Factor: 0.895
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Merlino A, Fuchs MR, Pica A, Balsamo A, Dworkowski FSN, Pompidor G, Mazzarella L, Vergara A
* Selective X-ray-induced NO photodissociation in haemoglobin crystals: evidence from a Raman-assisted crystallographic study (285 visite)
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2013 Jan; 69: 137-140.
Impact Factor: 7.232
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Accardo A, Ringhieri P, Tesauro D, Morelli G
* Liposomes derivatized with tetrabranched neurotensin peptides via click chemistry reactions (362 visite)
New J Chem (ISSN: 1144-0546), 2013; 37(11): 3528-3534.
Impact Factor: 3.159
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Merlino A, Fuchs MR, Pica A, Balsamo A, Dworkowski FSN, Pompidor G, Mazzarella L, Vergara A
* Selective X-Ray Induced No-Photodissociation In Hemoglobin Crystals: Evidence From A Raman Assisted-Crystallographic Study (270 visite)
Acta Cryst D 69, 2013; 1: 137-140.
Impact Factor: 0
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Russo Krauss I, Merlino A, Randazzo A, Novellino E, Mazzarella L, Sica F
* High-resolution structures of two complexes between thrombin and thrombin-binding aptamer shed light on the role of cations in the aptamer inhibitory activity (483 visite)
Nucleic Acids Res (ISSN: 0305-1048, 1362-4962, 1362-4962electronic), 2012 Sep; 40(16): 8119-8128.
Impact Factor: 8.278
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Alterio V, Di Fiore A, D'Ambrosio K, Supuran CT, De Simone G
* Multiple binding modes of inhibitors to carbonic anhydrases: How to design specific drugs targeting 15 different isoforms? (394 visite)
Chem Rev (ISSN: 0009-2665), 2012 Sep; 112(8): 4421-4468.
Impact Factor: 41.298
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Greco A, Petretta MP, Larobina M, Gargiulo S, Panico M, Nekolla SG, Esposito G, Petretta M, Brunetti A, Cuocolo A
* Reproducibility and accuracy of non-invasive measurement of infarct size in mice with high-resolution PET/CT (365 visite)
J Nucl Cardiol (ISSN: 1532-6551, 1071-3581, 1532-6551electronic), 2012 Jun; 19(3): 492-499.
Impact Factor: 2.847
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Maglione M, Bush A, Montella S, Mollica C, Manna A, Esposito A, Santamaria F
* Progression of lung disease in primary ciliary dyskinesia: Is spirometry less accurate than CT? (341 visite)
Pediatr Pulmonol (ISSN: 8755-6863), 2012 May; 47(5): 498-504.
Impact Factor: 2.375
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Esposito L, Ruggiero A, Masullo M, Ruocco MR, Lamberti A, Arcari P, Zagari A, Vitagliano L
* Crystallographic and spectroscopic characterizations of Sulfolobus solfataricus TrxA1 provide insights into the determinants of thioredoxin fold stability (283 visite)
J Struct Biol (ISSN: 1047-8477), 2012 Feb; 177(2): 506-512.
Impact Factor: 3.361
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Montella S, Maglione M, Bruzzese D, Mollica C, Pignata C, Aloj G, Manna A, Esposito A, Mirra V, Santamaria F
* Magnetic resonance imaging is an accurate and reliable method to evaluate non-cystic fibrosis paediatric lung disease (295 visite)
Respirology (ISSN: 1323-7799, 1440-1843electronic), 2012 Jan; 17(1): 87-91.
Impact Factor: 2.781
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Accardo A, Salsano G, Morisco A, Aurilio M, Parisi A, Maione F, Cicala C, Tesauro D, Aloj L, De Rosa G, Morelli G
* Peptide-modified liposomes for selective targeting of bombesin receptors overexpressed by cancer cells: A potential theranostic agent (338 visite)
Int J Nanomed (ISSN: 1176-9114, 1178-2013, 1178-2013electronic), 2012; 7: 2007-2017.
Impact Factor: 3.463
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Ruggiero A, Dattelbaum JD, Pennacchio A, Iozzino L, Staiano M, Luchansky MS, Der BS, Berisio R, D'Auria S, Vitagliano L
* Crystallization and preliminary X-ray crystallographic analysis of ligand-free and arginine-bound forms of Thermotoga maritima arginine-binding protein (342 visite)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2011 Nov 1; 67(11): 1462-1465.
Impact Factor: 0.506
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Malgieri G, Zaccaro L, Leone M, Bucci E, Esposito S, Baglivo I, Del Gatto A, Russo L, Scandurra R, Pedone PV, Fattorusso R, Isernia C
* Zinc to Cadmium Replacement in the A. thaliana SUPERMAN Cys(2)His(2) Zinc Finger Induces Structural Rearrangements of Typical DNA Base Determinant Positions (381 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2011 Nov; 95(11): 801-810.
Impact Factor: 2.87
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Accardo A, Morisco A, Tesauro D, Pedone C, Morelli G
* Naposomes: A new class of peptide-derivatized, target-selective multimodal nanoparticles for imaging and therapeutic applications (387 visite)
Ther Deliv (ISSN: 2041-5990), 2011 Feb; 2(2): 235-257.
Impact Factor: 0
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Ruggiero A, Squeglia F, Pirone L, Correale S, Berisio R
* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a major fragment of the resuscitation-promoting factor RpfB from Mycobacterium tuberculosis (356 visite)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2011 Jan 1; 67(1): 164-168.
Impact Factor: 0.506
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Di Fiore A, Maresca A, Alterio V, Supuran CT, De Simone G
* Carbonic anhydrase inhibitors: X-ray crystallographic studies for the binding of N-substituted benzenesulfonamides to human isoform II (324 visite)
Chem Commun (ISSN: 1359-7345, 1364-548x, 1364-548xelectronic), 2011; 47(42): 11636-11638.
Impact Factor: 6.169
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Ruggiero A, Squeglia F, Izzo V, Silipo A, Vitagliano L, Molinaro A, Berisio R
* Expression, purification, crystallization and preliminary x-ray crystallographic analysis of the peptidoglycan binding region of the ser/thr kinase PrkC from staphylococcus aureus (335 visite)
Protein Pept Lett (ISSN: 0929-8665, 1875-5305), 2010 Oct; 17(10): 1296-1299.
Impact Factor: 1.849
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Ferro A, Greco A, Gargiulo S, Larobina M, Petretta MP, Esposito G, Panico M, Nekolla SG, Brunetti A, Cuocolo A
* Reproducibility of Quantitative Measurement of Infarct Size in Mice With High-Resolution PET/CT Imaging (324 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2010 Oct; 37: N/D-N/D.
Impact Factor: 5.036
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Alterio V, Monti SM, Truppo E, Pedone C, Supuran CT, De Simone G
* The first example of a significant active site conformational rearrangement in a carbonic anhydrase-inhibitor adduct: The carbonic anhydrase I-topiramate complex (380 visite)
Org Biomol Chem (ISSN: 1477-0520, 1477-0539, 1477-0539electronic), 2010 Sep 7; 8(15): 3528-3533.
Impact Factor: 3.451
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Di Fiore A, Monti SM, Innocenti A, Winum J-Y, De Simone G, Supuran CT
* Carbonic anhydrase inhibitors: Crystallographic and solution binding studies for the interaction of a boron-containing aromatic sulfamide with mammalian isoforms I-XV (320 visite)
Bioorg Med Chem Lett Bioorganic And Medicinal Chemistry Letters (ISSN: 0960-894x), 2010 Jun 15; 20(12): 3601-3605.
Impact Factor: 2.661
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Diana D, Ziaco B, Scarabelli G, Pedone C, Colombo G, D'Andrea LD, Fattorusso R
* Structural analysis of a helical peptide unfolding pathway (404 visite)
Chemistry (ISSN: 1521-3765, 0947-6539, 1521-3765electronic), 2010 May 10; 16(18): 5400-5407.
Impact Factor: 5.476
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De Simone G, Supuran CT
* Carbonic anhydrase IX: Biochemical and crystallographic characterization of a novel antitumor target (362 visite)
Bba-Gen Subjects (ISSN: 1570-9639, 0006-3002, 0925-4439), 2010 Feb; 1804(2): 404-409.
Impact Factor: 2.773
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Ruggiero A, Squeglia F, Esposito C, Marasco D, Pedone E, Pedone C, Berisio R
* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of the resuscitation promoting factor interacting protein RipA from M. tuberculosis (323 visite)
Protein Pept Lett (ISSN: 0929-8665, 1875-5305), 2010 Jan; 17(1): 70-73.
Impact Factor: 1.849
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Merlino A, Vitagliano L, Howes BD, Verde C, Di Prisco G, Smulevich G, Sica F, Vergara A
* Combined Crystallographic and Spectroscopic Analysis of Trematomus bernacchii Hemoglobin Highlights Analogies and Differences in the Peculiar Oxidation Pathway of Antarctic Fish Hemoglobins (368 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2009 Dec; 91(12): 1117-1125.
Impact Factor: 2.605
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Vitagliano L, Stanzione F, De Simone A, Esposito L
* Dynamics and Stability of Amyloid-Like Steric Zipper Assemblies with Hydrophobic Dry Interfaces (379 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2009 Dec; 91(12): 1161-1171.
Impact Factor: 2.605
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Varrone A, Sjoholm N, Eriksson L, Gulyas B, Halldin C, Farde L
* Advancement in PET quantification using 3D-OP-OSEM point spread function reconstruction with the HRRT (348 visite) (PDF 248 visite)
Eur J Nucl Med (ISSN: 1619-7070, 1619-7089, 0340-6997), 2009 Oct; 36(10): 1639-1650.
Impact Factor: 4.531
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Moccia M, Musumeci D, Roviello GN, Fusco S, Valente M, Bucci EM, Sapio R, Pedonea C, Netti PA
* Preliminary studies on noncovalent hyperbranched polymers based on PNA and DNA building blocks (590 visite)
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2009 Oct; 15(10): 647-653.
Impact Factor: 1.807
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Montella S, Santamaria F, Salvatore M, Maglione M, Iacotucci P, De Santi MM, Mollica C
* Lung disease assessment in primary ciliary dyskinesia: a comparison between chest high-field magnetic resonance imaging and high-resolution computed tomography findings (367 visite)
Ital J Pediatr (ISSN: 1824-7288, 1720-8424), 2009 Sep 6; 35(24): 24-24.
Impact Factor: 0.722
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Montella S, Santamaria F, Salvatore M, Pignata C, Maglione M, Iacotucci P, Mollica C
* Assessment of chest high-field magnetic resonance imaging in children and young adults with noncystic fibrosis chronic lung disease: comparison to high-resolution computed tomography and correlation with pulmonary function (219 visite)
Invest Radiol (ISSN: 1536-0210, 0020-9996, 1536-0210electronic), 2009 Sep; 44(9): 532-538.
Impact Factor: 4.85
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Ruggiero A, Lanzotti MA, Ruocco MR, Grimaldi P, Marasco D, Arcari P, Masullo M, Zagari A, Vitagliano L
* Crystallization and preliminary X-ray crystallographic analysis of two dimeric hyperthermostable thioredoxins isolated from Sulfolobus solfataricus (306 visite)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2009 Jun; 65: 604-607.
Impact Factor: 0.551
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Vitagliano L, Vergara A, Bonomi G, Merlino A, Verde C, Di Prisco G, Howes BD, Smulevich G, Mazzarella L
* Spectroscopic and crystallographic characterization of a tetrameric hemoglobin oxidation reveals structural features of the functional intermediate relaxed/tense state (363 visite)
J Am Chem Soc (ISSN: 0002-7863, 0002-2786, 1520-5126), 2008 Sep 13; 130(32): 10527-10535.
Impact Factor: 8.091
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Ruggiero A, Chambery A, Di Maro A, Parente A, Berisio R
* Atomic Resolution (1. 1 Angstrom) Structure Of The Ribosome-Inactivating Protein Pd-L4 From Phytolacca Dioica L. Leaves (350 visite)
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2008 Apr; 71(1): 8-15.
Impact Factor: 3.419
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Licciardello MP, D'Agata R, Grasso G, Simone S, Spoto G
* Atmospheric Pressure Laser Desorption Mass Spectrometry based methods for the study of traditional painting materials (208 visite)
Lasers Conserv Artworks Proc Int Conf Lacona Vii (ISSN: 9780-4154), 2008; N/D: 67-72.
Impact Factor: 0
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Vitagliano L, Vergara A, Bonomi G, Merlino A, Verde C, Di Prisco G, Howes BD, Smulevich G, Mazzarella L
* Spectroscopic And Crystallographic Characterization Of A Tetrameric Hemoglobin Oxidation Pathway Reveals Structural Features Of A Functional Intermediate R/T State (261 visite)
Biophys J, 2008; 94: 4031-4040.
Impact Factor: 3.832
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Vergara A, Vitagliano L, Verde C, di Prisco G, Mazzarella L
* Spectroscopic and crystallographic characterization of bis-histidyl adducts in tetrameric hemoglobins (383 visite)
Method Enzymol (ISSN: 0076-6879, 1557-7988electronic), 2008; 436: 425-444.
Impact Factor: 2.312
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Vergara A, Vitagliano L, Di Prisco G, Verde C, Mazzarella L
* Spectroscopic And Crystallographic Characterization Of Hemichromes In Tetrameric Hemoglobins (303 visite)
Methods In Enzymology, 2008; 436: 421-440.
Impact Factor: 2.194
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Ruggiero A, Tizzano B, Geerlof A, Pedone E, Pedone C, Wilmanns M, Berisio R
* Expression, purification, crystallization and preliminary X-ray crystallographic analysis of a resuscitation-promoting factor from Mycobacterium tuberculosis (352 visite)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2007 Oct 1; 63(10): 870-873.
Impact Factor: 0.645
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Alterio V, De Simone G, Monti SM, Scozzafava A, Supuran CT
* Carbonic anhydrase inhibitors: Inhibition of human, bacterial, and archaeal isozymes with benzene-1, 3-disulfonamides-Solution and crystallographic studies (307 visite)
Bioorg Med Chem Lett Bioorganic And Medicinal Chemistry Letters (ISSN: 0960-894x), 2007 Sep 1; 17(15): 4201-4207.
Impact Factor: 2.604
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Cusanno F, Cisbani E, Colilli S, Fratoni R, Garibaldi F, Giuliani F, Gricia M, Lucentini M, Magliozzi ML, Santarivenere F, Torrioli S, Cinti MN, Pani R, Pellegrini R, Simonetti G, Schillaci O, Del Vecchio S, Salvatore M, Majewski S, De Vincentis G, Scopinaro F
* Results of clinical trials with SPEM (248 visite)
Nucl Instrum Methods Phys Res Sect A, 2007 Feb 1; 497(1): 46-50.
Impact Factor: 3.221
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Aloj L, Aurilio M, Rinaldi V, D'Ambrosio L, Tesauro D, Peitl PK, Maina T, Mansi R, Von Guggenberg E, Joosten L, Sosabowski JK, Breeman WA, De Blois E, Koelewijn S, Melis M, Waser B, Beetschen K, Reubi JC, De Jong M
* The EEE project (431 visite)
Proc Int Cosm Ray Conf Icrc Universidad Nacional Autonoma De Mexico, 2007; 5(HEPART2): 977-980.
Impact Factor: 0
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Garibaldi F, Cisbani E, Colilli S, Cusanno F, Fratoni R, Giuliani F, Gricia M, Lucentini M, Fratoni R, Lo Meo S, Magliozzi ML, Santanvenere F, Cinti MN, Pani R, Pellegrini R, Simonetti G, Schillaci O, Del Vecchio S, Salvatore M, Majewski S, Lanza RC, De Vincentis G, Scopinaro F
* Molecular imaging: High-resolution detectors for early diagnosis and therapy monitoring of breast cancer (313 visite)
Nucl Instrum Meth A (ISSN: 0168-9002), 2006 Dec 20; 569(2SPEC.ISS.): 286-290.
Impact Factor: 1.185
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Menchise V, De Simone G, Di Fiore A, Scozzafava A, Supuran CT
* Carbonic anhydrase inhibitors: X-ray crystallographic studies for the binding of 5-amino-1, 3, 4-thiadiazole-2-sulfonamide and 5-(4-amino-3-chloro-5-fluorophenylsulfonamido)1, 3, 4-thiadiazole-2-sulfon amide to human isoform II (285 visite)
Bioorganic & Medicinal Chemistry Letters (ISSN: 0960-894x), 2006 Dec 15; 16(24): 6204-6208.
Impact Factor: 2.538
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Mazzarella L, Vergara A, Vitagliano L, Merlino A, Bonomi G, Scala S, Verde C, Di Prisco G
* High resolution crystal structure of deoxy hemoglobin from Trematomus bernacchii at different pH values: The role of histidine residues in modulating the strength of the root effect (354 visite)
Proteins (ISSN: 0887-3585, 1097-0134, 1097-0134electronic), 2006 Nov 1; 65(2): 490-498.
Impact Factor: 3.73
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Santamaria F, Montella S, Camera L, Palumbo C, Greco L, Boner AL
* Lung structure abnormalities, but normal lung function in pediatric bronchiectasis (373 visite)
Chest (ISSN: 0012-3692), 2006 Sep; 130(2): 480-486.
Impact Factor: 3.924
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Ruggiero A, Masullo M, Arcari P, Raimo G, Vitagliano L, Zagari A
* Crystallization And Preliminary X-Ray Crystallographic Analysis Of The Sulfolobus Solfataricus Nucleotide-Exchange Factor 1 Beta (312 visite)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2005 Nov; 61(11): 1000-1002.
Impact Factor: 0.568
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Ruggiero A, Ruocco MR, Grimaldi P, Arcari P, Masullo M, Zagari A, Vitagliano L
* Crystallization and preliminary X-ray crystallographic analysis of Sulfolobus solfataricus thioredoxin reductase (297 visite)
Nucleosides Nucleotides Nucleic Acids (ISSN: 1744-3091, 1744-4309), 2005 Oct; 61: 906-909.
Impact Factor: 0.568
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De Simone G, Di Fiore A, Menchise V, Pedone C, Antel J, Casini A, Scozzafava A, Wurl M, Supuran CT
* Carbonic anhydrase inhibitors. Zonisamide is an effective inhibitor of the cytosolic isozyme II and mitochondrial isozyme V: solution and X-ray crystallographic studies (324 visite)
Bioorg Med Chem Lett Bioorganic And Medicinal Chemistry Letters (ISSN: 0960-894x), 2005 May 2; 15(9): 2315-2320.
Impact Factor: 2.478
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Galdiero S, Gouaux E
* High Resolution Crystallographic Studies Of Alpha-Hemolysin-Phospholipid Complexes Define Heptamer-Lipid Head Group Interactions: Implication For Understanding Protein-Lipid Interactions (302 visite)
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic), 2004 Jun; 13(6): 1503-1511.
Impact Factor: 4.116
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De Simone G, Menchise V, Omaggio S, Pedone C, Scozzafava A, Supuran CT
* Design of weakly basic thrombin inhibitors incorporating novel P1 binding functions: Molecular and X-ray crystallographic studies (324 visite)
Biochemistry (ISSN: 0006-2960, 1520-4995, 1520-4995electronic), 2003 Sep 5; 42(30): 9013-9021.
Impact Factor: 3.922
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Esposito L, Sica F, Raia CA, Giordano A, Rossi M, Mazzarella L, Zagari A
* Crystal Structure Of The Alcohol Dehydrogenase From The Hyperthermophilic Archaeon Sulfolobus Solfataricus At 1. 85 Angstrom Resolution (390 visite)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2002 Apr 26; 318(2): 463-477.
Impact Factor: 5.359
Dettagli Esporta in BibTeX Esporta in EndNote
Esposito L, Vitagliano L, Mazzarella L
* Recent advances in atomic resolution protein crystallography (340 visite)
Protein Pept Lett (ISSN: 0929-8665, 1875-5305), 2002 Apr; 9(2): 95-105.
Impact Factor: 0.622
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Berisio R, Sica F, Lamzin VS, Wilson KS, Zagari A, Mazzarella L
* Atomic resolution structures of ribonuclease A at six pH values (459 visite)
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2002; 58(3): 441-450.
Impact Factor: 1.76
Dettagli Esporta in BibTeX Esporta in EndNote
Berisio R, Sica F, Lamzin VS, Wilson KS, Zagari A, Mazzarella L
* Atomic Resolution Structures Of Rnase A At Six Ph Values (217 visite)
Acta Crystallogr D Biol Crystallogr, 2002; N/D: 441-450.
Impact Factor: 7.232
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Celentano L, Laccetti P, Liuzzi R, Mettivier G, Montesi MC, Autiero M, Riccio P, Roberti G, Russo P, Salvatore M
* Preliminary tests of a prototype system for optical and radionuclide imaging in small animals (304 visite)
Ieee Nuclear Science Symposium And Medical Imaging Conference, 2002; 3: 1746-1750.
Impact Factor: 0
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De Simone G, Menchise V, Manco G, Mandrich L, Sorrentino N, Lang D, Rossi M, Pedone C
* The crystal structure of a hyper-thermophilic carboxylesterase from the archaeon Archaeoglobus fulgidus (339 visite)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2001 Nov 30; 314(3): 507-518.
Impact Factor: 5.826
Dettagli Esporta in BibTeX Esporta in EndNote
Berisio R, Viguera A, Serrano L, Wilmanns M
* Atomic resolution structure of a mutant of the spectrin SH3 domain (268 visite)
Acta Crystallogr D Biol Crystallogr (ISSN: 0907-4449, 0907-4449linking), 2001 Feb; 57(2): 337-340.
Impact Factor: 2.124
Dettagli Esporta in BibTeX Esporta in EndNote
Esposito L, Vitagliano L, Zagari A, Mazzarella L
Experimental evidence for the correlation of bond distances in peptide groups detected in ultrahigh-resolution protein structures (266 visite)
Protein Eng (ISSN: 0269-2139, 0269-2139print, 0269-2139linking), 2000 Dec; 13(12): 825-828.
Impact Factor: 2.442
Dettagli Esporta in BibTeX Esporta in EndNote
Esposito L, Vitagliano L, Zagari A, Mazzarella L
Pyramidalization of backbone carbonyl carbon atoms in proteins (402 visite)
Protein Sci (ISSN: 0961-8368, 1469-896xelectronic), 2000 Oct; 9(10): 2038-2042.
Impact Factor: 3.869
Dettagli Esporta in BibTeX Esporta in EndNote
Esposito L, Vitagliano L, Sica F, Sorrentino G, Zagari A, Mazzarella L
The ultrahigh resolution crystal structure of ribonuclease A containing an isoaspartyl residue: Hydration and sterochemical analysis (408 visite)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 2000 Mar 31; 297(3): 713-732.
Impact Factor: 5.388
Dettagli Esporta in BibTeX Esporta in EndNote
Berisio R, Vitagliano L, Mazzarella L, Zagari A
Crystal Structure Of A Collagen-Like Polypeptide With Repeating Sequence Pro-Hyp-Gly At 1. 4 Ang Resolution: Implications For Collagen Hydration (396 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2000; 56(1): 8-13.
Impact Factor: 2.405
Dettagli Esporta in BibTeX Esporta in EndNote
Berisio R, Lamzin VS, Sica F, Wilson KS, Zagari A, Mazzarella L
Protein titration in the crystal state (357 visite)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 1999 Oct 1; 292(4): 845-854.
Impact Factor: 5.501
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Kramer RZ, Vitagliano L, Bella J, Berisio R, Mazzarella L, Brodsky B, Zagari A, Berman HM
X-ray crystallographic determination of a collagen-like peptide with the repeating sequence (Pro-Pro-Gly) (376 visite)
J Mol Biol (ISSN: 0022-2836, 1089-8638, 1089-8638electronic), 1998 Jul 24; 280(4): 623-638.
Impact Factor: 5.803
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Zanotti G, Saviano M, Saviano G, Tancredi T, Rossi F, Pedone C, Benedetti E
Structure of cyclic peptides: the crystal and solution conformation of cyclo(Phe-Phe-Aib-Leu-Pro) (398 visite)
Journal Of Peptide Research (ISSN: 1397-002x), 1998 Jun; 51(6): 460-466.
Impact Factor: 1.125
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Crisma M, Formaggio F, Valle G, Toniolo C, Saviano M, Iacovino R, Zaccaro L, Benedetti E
Experimental evidence at atomic resolution for intramolecular N- H···π (phenyl) interactions in a family of amino acid derivatives (378 visite)
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 1997; 42(1): 1-6.
Impact Factor: 2.425
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Soricelli A, Mainenti PP, Leone D, Discepolo A, Romano M, Varrone A, Servillo G, Serio S, Brunetti A, Salvatore M
Evaluation of brain perfusion with high resolution single photon emission tomography in the diagnosis of brain death (222 visite)
Minerva Anestesiol (ISSN: 0375-9393), 1996 Jun; 62(6): 209-212.
Impact Factor: 1.627
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Cucinotta V, Grasso G, Pedotti S, Rizzarelli E, Vecchio G, Di Blasio B, Isernia C, Saviano M, Pedone C
A Platinum(II) Diamino-β-cyclodextrin Complex: A Crystallographic and Solution Study. Synthesis and Structural Characterization of a Platinum(II) Complex of 6A, 6B-Diamino-6A, 6B-dideoxycyclomaltoheptaose (265 visite)
Inorg Chem (ISSN: 0020-1669, 1520-510x, 1520-510xelectronic), 1996; 35(26): 7535-7540.
Impact Factor: 2.736
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Bonomo RP, De Flora A, Rizzarelli E, Santoro AM, Tabbì G, Tonetti M
Copper(II) complexes encapsulated in human red blood cells (558 visite)
J Chem Res (ISSN: 0162-0134, 1873-3344, 0162-0134print), 1995 Sep; 59(4): 773-784.
Impact Factor: 1.342
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Ferrara LA, Mancini M, Celentano A, Galderisi M, Iannuzzi R, Marotta T, Gaeta I
Early changes of the arterial carotid wall in uncomplicated primary hypertensive patients: Study by ultrasound high-resolution B-mode imaging (252 visite)
Arterioscler Thromb Vasc Biol Arteriosclerosis Thrombosis And Vascular Biology (ISSN: 1079-5642, 1049-8834), 1994 Sep; 14(8): 1290-1296.
Impact Factor: 5.317
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Alfano B, Bandettini A, Bencivelli W, Bertolucci E, Bottigli U, Conti M, Del Guerra A, Fantacci ME, Gambaccini M, Larobina M, Marziani M, Randaccio P, Rosso V, Russo P, Stefanini A
Digital imaging in radiology: preliminary results obtained with a high spatial resolution 2D silicon detector (285 visite)
Ieee Transactions On Nuclear Science (ISSN: 0018-9499), 1993 Sep; 40(4pt1): 987-991.
Impact Factor: 1.048
Dettagli Esporta in BibTeX Esporta in EndNote
107 Records (101 escludendo Abstract e Conferenze).
Impact factor totale: 357.84 (348.33 escludendo Abstract e Conferenze).
Impact factor a 5 anni totale: 374.245 (365.437 escludendo Abstract e Conferenze).
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