Keywords Parole chiave: Dental Implant, Histomorphometry, Insertion Torque, Minipig Model, Resonance Frequency Analysis, Muct, Animals, Dental Implantation, Endosseous, Humans, Osseointegration, Pilot Projects, Reproducibility Of Results, Swine, Miniature, X-Ray Microtomography, μct
Affiliations Affiliazioni: *** IBB - CNR ***
Institute of Biostructure and Bioimaging, National Research Council, Via T. De Amicis 95, 80145 Naples, Italy; CEINGE scarl, Via G. Salvatore 486, 80145 Naples, Italy. Electronic address: matteo.gramanzini@ibb.cnr.it., Institute of Biostructure and Bioimaging, National Research Council, Via T. De Amicis 95, 80145 Naples, Italy; CEINGE scarl, Via G. Salvatore 486, 80145 Naples, Italy. Electronic address: sara.gargiulo@ibb.cnr.it., Department of Neurosciences, Reproductive and Odontostomatological Sciences, School of Medicine, University "Federico II", Via Pansini 5, 80131 Naples, Italy. Electronic address: fernandozarone@mac.com., Institute of Biostructure and Bioimaging, National Research Council, Via T. De Amicis 95, 80145 Naples, Italy. Electronic address: rosario.megna@ibb.cnr.it., Department of Architecture and Industrial Design, Second University of Naples, Borgo San Lorenzo, 81031 Aversa, Italy. Electronic address: antonio.apicella@unina2.it., Department of Architecture and Industrial Design, Second University of Naples, Borgo San Lorenzo, 81031 Aversa, Italy. Electronic address: raffaella.aversa@unina2.it., IRCCS SDN, Via E. Gianturco 113, 80143 Naples, Italy. Electronic address: marsalva@unina.it., Institute of Biostructure and Bioimaging, National Research Council, Via T. De Amicis 95, 80145 Naples, Italy. Electronic address: marcello.mancini@ibb.cnr.it., Department of Neurosciences, Reproductive and Odontostomatological Sciences, School of Medicine, University "Federico II", Via Pansini 5, 80131 Naples, Italy; Department of Architecture and Industrial Design, Second University of Naples, Borgo San Lorenzo, 81031 Aversa, Italy. Electronic address: errestino@libero.it., Department of Advanced Medical Sciences, University "Federico II", Via Pansini 5, 80145 Naples, Italy; CEINGE scarl, Via G. Salvatore 486, 80145 Naples, Italy. Electronic address: brunetti@unina.it.,
CEINGE scarl, Via G. Salvatore 486, 80145 Naples, Italy. Electronic address: matteo.gramanzini@ibb.cnr.it.
Department of Neuroscien
References Riferimenti: Not available. Non disponibili.
Combined microcomputed tomography, biomechanical and histomorphometric analysis of the peri-implant bone: a pilot study in minipig model
OBJECTIVES: To present a practical approach that combines biomechanical tests, microcomputed tomography (μCT) and histomorphometry, providing quantitative results on bone structure and mechanical properties in a minipig model, in order to investigate the specific response to an innovative dental biomaterial. METHODS: Titanium implants with innovative three-dimensional scaffolds were inserted in the tibias of 4 minipigs. Primary stability and osseointegration were investigated by means of insertion torque (IT) values, resonance frequency analysis (RFA), bone-to-implant contact (BIC), bone mineral density (BMD) and stereological measures of trabecular bone. RESULTS: A significant positive correlation was found between IT and RFA (r=0.980, p=0.0001). BMD at the implant sites was 18% less than the reference values (p=0.0156). Peri-implant Tb.Th was 50% higher, while Tb.N was 50% lower than the reference zone (p<0.003) and they were negatively correlated (r=-0.897, p=0.006). SIGNIFICANCE: μCT increases evaluation throughput and offers the possibility for qualitative three-dimensional recording of the bone-implant system as well as for non-destructive evaluation of bone architecture and mineral density, in combination with conventional analysis methods. The proposed multimodal approach allows to improve accuracy and reproducibility for peri-implant bone measurements and could support future investigations.
Combined microcomputed tomography, biomechanical and histomorphometric analysis of the peri-implant bone: a pilot study in minipig model
Kim YH, Shin SW, Pellicano R, Fagoonee S, Choi IJ, Kim YI, Park B, Choi JM, Kim SG, Choi J, Park JY, Oh S, Yang HJ, Lim JH, Im JP, Kim JS, Jung HC, Ponzetto A, Figura N, Malfertheiner P, Choi IJ, Kook MC, Kim YI, Cho SJ, Lee JY, Kim CG, Park B, Nam BH, Bae SE, Choi KD, Choe J, Kim SO, Na HK, Choi JY, Ahn JY, Jung KW, Lee J, Kim DH, Chang HS, Song HJ, Lee GH, Jung HY, Seta T, Takahashi Y, Noguchi Y, Shikata S, Sakai T, Sakai K, Yamashita Y, Nakayama T, Leja M, Park JY, Murillo R, Liepniece-karele I, Isajevs S, Kikuste I, Rudzite D, Krike P, Parshutin S, Polaka I, Kirsners A, Santare D, Folkmanis V, Daugule I, Plummer M, Herrero R, Tsukamoto T, Nakagawa M, Kiriyama Y, Toyoda T, Cao X, Corral JE, Mera R, Dye CW, Morgan DR, Lee YC, Lin JT, Garcia Martin R, Matia Cubillo A, Lee SH, Park JM, Han YM, Ko WJ, Hahm KB, Leontiadis GI, Ford AC, Ichinose M, Sugano K, Jeong M, Park JM, Han YM, Park KY, Lee DH, Yoo JH, Cho JY, Hahm KB, Bang CS, Baik GH, Shin IS, Kim JB, Suk KT, Yoon JH, Kim YS, Kim DJ * Helicobacter pylori Eradication for Prevention of Metachronous Recurrence after Endoscopic Resection of Early Gastric Cancer(207 visite) N Engl J Med (ISSN: 0028-4793, 0028-4793linking, 1533-4406electronic), 2015 Jun; 30642104201566393291: 749-756. Impact Factor:59.558 DettagliEsporta in BibTeXEsporta in EndNote
Testino G, Leone S, Fagoonee S, Del Bas JM, Rodriguez B, Puiggros F, Marine S, Rodriguez MA, Morina D, Armengol L, Caimari A, Arola L, Cimini FA, Barchetta I, Carotti S, Bertoccini L, Baroni MG, Vespasiani-gentilucci U, Cavallo MG, Morini S, Nelson JE, Roth CL, Wilson LA, Yates KP, Aouizerat B, Morgan-stevenson V, Whalen E, Hoofnagle A, Mason M, Gersuk V, Yeh MM, Kowdley KV, Lee SM, Jun DW, Cho YK, Jang KS, Kucukazman M, Ata N, Dal K, Yeniova AO, Kefeli A, Basyigit S, Aktas B, Akin KO, Agladioglu K, Ure OS, Topal F, Nazligul Y, Beyan E, Ertugrul DT, Catena C, Cosma C, Camozzi V, Plebani M, Ermani M, Sechi LA, Fallo F, Goto Y, Ray MB, Mendenhall CL, French SW, Gartside PS Serum vitamin A deficiency and increased intrahepatic expression of cytokeratin antigen in alcoholic liver disease(420 visite) Hepatology (ISSN: 1827-1669electronic, 0026-4806linking), 1988 Sep; 83120693611123109(5): 1019-1026. Impact Factor:0.913 DettagliEsporta in BibTeXEsporta in EndNote
254 Records (247 escludendo Abstract e Conferenze). Impact factor totale: 1193.328 (1163.528 escludendo Abstract e Conferenze). Impact factor a 5 anni totale: 1150.627 (1117.555 escludendo Abstract e Conferenze).
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