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A novel fully integrated handheld gamma camera (277 views) (PDF restricted 60 views)

Massari R, Ucci A, Campisi C, Scopinaro F, Soluri A

Nuclear Instruments And Methods In Physics Research A, 2016 Jan; 832: 271-278.

Abstract

In this paper, we present an innovative, fully integrated handheld gamma camera, namely designed to gather in the same device the gamma ray detector with the display and the embedded computing system. The low power consumption allows the prototype to be battery operated.
To be useful in radioguided surgery, an intraoperative gamma camera must be very easy to handle since it must be moved to find a suitable view. Consequently, we have developed the first prototype of a fully integrated, compact and lightweight gamma camera for radiopharmaceuticals fast imaging. The device can operate without cables across the sterile field, so it may be easily used in the operating theater for radioguided surgery.
The prototype proposed consists of a Silicon Photomultiplier (SiPM) array coupled with a proprietary scintillation structure based on CsI(Tl) crystals. To read the SiPM output signals, we have developed a very low power readout electronics and a dedicated analog to digital conversion system. One of the most critical aspects we faced designing the prototype was the low power consumption, which is mandatory to develop a battery operated device.
We have applied this detection device in the lymphoscintigraphy technique (sentinel lymph node mapping) comparing the results obtained with those of a commercial gamma camera (Philips SKYLight). The results obtained confirm a rapid response of the device and an adequate spatial resolution for the use in the scintigraphic imaging.
This work confirms the feasibility of a small gamma camera with an integrated display. This device is designed for radioguided surgery and small organ imaging, but it could be easily combined into surgical navigation systems.


Affiliations ▼
*** IBB - CNR Affiliation

Biostructure and Bioimaging Institute (IBB), National Research Council of Italy (CNR), Rome, Italy

University of Rome “La Sapienza”, S. Andrea Hospital, Rome, Italy

Details ▼
Impact factor: 1.2, 5-year impact factor: 1.102

Paper type: Full Length Journal Article,

Keywords: Nuclear Medicine Imaging; Intraoperative Gamma Camera; Portable Gamma Camera; Handheld Scintigraphic Device; Silicon Photomultiplier,

Url: http://dx.doi.org/10.1016/j.nima.2016.06.124

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Cuocolo A, Breatnach E
Eur J Nucl Med Mol Imaging (ISSN: 1619-7089, 1619-7070, 0340-6997), 2010 Jan; 37(1): 163-167.

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* A new variable parallel holes collimator for scintigraphic device with validation method based on Monte Carlo simulations (80 views)
Trinci G, Massari R, Scandellari M, Boccalini S, Costantini S, Di Sero R, Basso A, Sala R, Scopinaro F, Soluri A
Nuclear Instruments And Methods In Physics Research Section A, 2010; 621(1-3): 406-412.

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* EANM procedure guideline for brain perfusion SPECT using Tc-99m-labelled radiopharmaceuticals, version (85 views)
Kapucu OL, Nobili F, Varrone A, Booij J, Vander Borght T, Nagren K, Darcourt J, Tatsch K, Van Laere KJ
Eur J Nucl Med Mol Imaging (ISSN: 1619-7070, 1619-7089, 0340-6997), 2009 Dec; 36(12): 2093-2102.

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* EANM procedure guidelines for PET brain imaging using [18F]FDG, version (96 views)
Varrone A, Asenbaum S, Vander Borght T, Booij J, Nobili F, Nagren K, Darcourt J, Kapucu OL, Tatsch K, Bartenstein P, Van Laere K
Eur J Nucl Med Mol Imaging (ISSN: 1619-7070, 1619-7089, 0340-6997), 2009 Dec; 36(12): 2103-2110.

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* Radiolabeled humanized anti-CD3 monoclonal antibody visilizumab for imaging human T-lymphocytes (91 views)
Malviya G, D'Alessandria C, Bonanno E, Vexler V, Massari R, Trotta C, Scopinaro F, Dierckx R, Signore A
Journal Of Nuclear Medicine (ISSN: 1535-5667electronic, 0161-5505linking), 2009 Oct; 50(10): 1683-1691.

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* EANM/ESC guidelines for radionuclide imaging of cardiac function (120 views)
Hesse B, Lindhardt TB, Acampa W, Anagnostopoulos C, Ballinger J, Bax JJ, Edenbrandt L, Flotats A, Germano G, Stopar TG, Franken P, Kelion A, Kjaer A, Le Guludec D, Ljungberg M, Maenhout AF, Marcassa C, Marving J, Mckiddie F, Schaefer WM, Stegger L, Underw
Eur J Nucl Med Mol Imaging (ISSN: 1619-7070, 1619-7089, 0340-6997), 2008 Apr; 35(4): 851-885.

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* Usefulness of [(111)In-DTPA(0)] octreotide scintigraphy in a family with von Hippel-Lindau disease (77 views)
Pulcrano M, Camera L, Pagano L, Del Vecchio S, Ferone D, Bodei L, Murgia A, Pace L, Storto G, Paganelli G, Colao A, Salvatore M, Lombardi G, Biondi B
J Endocrinol Invest Journal Of Endocrinological Investigation (ISSN: 0391-4097), 2008 Apr; 31(4): 352-359.

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* F-18-FDG PET/CT, Tc-99m-MIBI, and MRI in evaluation of patients with multiple myeloma (118 views)
Fonti R, Salvatore B, Quarantelli M, Sirignano C, Segreto S, Petruzziello F, Catalano L, Liuzzi R, Rotoli B, Del Vecchio S, Pace L, Salvatore M
Journal Of Nuclear Medicine (ISSN: 0161-5505, 0161-1550, 1535-5667), 2008 Feb; 49(2): 195-200.

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* High-Resolution Imaging System (HiRIS) based on H9500 PSPMT (82 views)
Trotta C, Massari R, Trinci G, Palermo N, Boccalini S, Scopinaro F, Soluri A
Nuclear Instruments And Methods In Physics Research Section A, 2008; 593(3): 454-458.

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* In vivo and in vitro characterization of CCK8 bearing a histidine-based chelator labeled with Tc-99m-tricarbonyl (101 views)
D'Andrea LD, Testa I, Panico M, Di Stasi R, Carac C, Tarallo L, Arra C, Barbieri A, Romanelli A, Aloj L
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2008; 90(5): 707-712.

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* White paper of the European Association of Nuclear Medicine (EANM) and the European Society of Radiology (ESR) on multimodality imaging (59 views)
Bischof Delaloye A, Carrio I, Cuocolo A, Knapp W, Gourtsoyiannis N, Mccall I, Reiser M, Silberman B
Eur J Nucl Med Mol Imaging (ISSN: 1619-7070, 1619-7089, 0340-6997), 2007 Sep; 34(8): 1147-1151.

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Molecular imaging (57 views)
Maggi A, Salvatore M
Q J Nucl Med Mol Imaging (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2007 Jun; 51(2): 95-95.

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* Nuclear imaging in cancer theranostics (89 views)
Del Vecchio S, Zannetti A, Fonti R, Pace L, Salvatore M
Q J Nucl Med Mol Imaging (ISSN: 1824-4785, 1824-4478, 1824-4785linking), 2007 Jun; 51(2): 152-163.

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* Sestamibi and FDG-PET scans to support diagnosis of jaw osteonecrosis (66 views)
Catalano L, Del Vecchio S, Petruzziello F, Fonti R, Salvatore B, Martorelli C, Califano C, Caparrotti G, Segreto S, Pace L, Rotoli B
Annals Of Hematology (ISSN: 0939-5555), 2007 Jun; 86(6): 415-423.

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* Peptide derivatized lamellar aggregates as target-specific MRI contrast agents (60 views)
Tesauro D, Accardo A, Gianolio E, Paduano L, Teixeira J, Schillén K, Aime S, Morelli G
Chembiochem (ISSN: 1439-4227, 1439-7633, 1439-7633electronic), 2007 May 25; 8(8): 950-955.

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* The (Tc(N)(PNP))2+ metal fragment labeled cholecystokinin-8 (CCK8) peptide for CCK-2 receptors imaging: In vitro and in vivo studies (66 views)
Agostini S, Bolzati C, Didonè E, Cavazza-Ceccato M, Refosco F, Aloj L, Arra C, Aurilio M, Tornesello AL, Tesauro D, Morelli G
J Pept Sci (ISSN: 1075-2617, 1099-1387, 1075-2617print), 2007 Apr; 13(4): 211-219.

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* Syllabus for postgraduate specialisation in Nuclear Medicine: 2006/07 update (58 views)
Cuocolo A, Milcinski M, Bischof Delaloye A
Eur J Nucl Med Mol Imaging (ISSN: 1619-7070, 1619-7089, 0340-6997), 2007 Mar; 34(3): 433-436.

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* EANM procedure guidelines for brain tumour imaging using labelled amino acid analogues (114 views)
Vander Borght T, Asenbaum S, Bartenstein P, Halldin C, Kapucu O, Van Laere K, Varrone A, Tatsch K
Eur J Nucl Med Mol Imaging (ISSN: 1619-7070, 1619-7089, 0340-6997), 2006 Nov; 33(11): 1374-1380.

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* Bombesin receptors and transplanted stem cells in rat brain: High-resolution scan with 99mTc BN1 (42 views)
Scopinaro F, Paschali E, Di Santo G, Antonellis T, Massari R, Trotta C, Gourni H, Bouziotis P, David V, Soluri A, Varvarigou AD
Nuclear Instruments And Methods In Physics Research Section A, 2006; 569(2SPEC.ISS.): 525-528.

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* High-resolution mini gamma camera for diagnosis and radio-guided surgery in diabetic foot infection (67 views)
Scopinaro F, Capriotti G, Di Santo G, Capotondi C, Micarelli A, Massari R, Trotta C, Soluri A
Nuclear Instruments And Methods In Physics Research Section A, 2006; 569(2SPEC.ISS.): 269-272.

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* High resolution mini-gammacamera and 99mTc [HMPAO] - leukocytes for diagnosis of infection and radioguided surgery in diabetic foot (87 views)
Soluri A, Massari R, Trotta C, Stella S, Cavaiola S, Capriotti G, Di Santo GP, Di Paolo ML, Mangano AM, Liberatore M, Micarelli A, Bruzzese A, Pasta V
Il Giornale Di Chirurgia (ISSN: 0391-9005), 2005 Jun; 26(6-7): 246-250.

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* New imaging probe with crystals integrated in the collimator's square holes (81 views)
Soluri A, Massari R, Trotta C, Montani L, Iurlaro G, Mangano AM, Scopinaro F, Scafè R
Nuclear Instruments And Methods In Physics Research Section A, 2005; 554(1-3): 331-339.

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* Tc-99m-MIBI in the evaluation of breast cancer biology (155 views)
Del Vecchio S, Zannetti A, Fonti R, Iommelli F, Salvatore M
Breast Cancer (ISSN: 9783-540367802), 2004 Jun; 1: 71-81.

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* Tc-99m-MIBI in the evaluation of breast cancer biology (133 views)
Del Vecchio S, Salvatore M
Eur J Nucl Med Mol Imaging (ISSN: 1619-7070, 1619-7089, 0340-6997), 2004 Jun; 31(SUPPL.1): S88-S88.

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* In vitro and in vivo evaluation of In-111-DTPAGlu-G-CCK8 for cholecystokinin-B receptor imaging (93 views)
Aloj L, Caracò C, Panico M, Zannetti A, Del Vecchio S, Tesauro D, De Luca S, Arra C, Pedone C, Morelli G, Salvatore M
Journal Of Nuclear Medicine (ISSN: 1535-5667, 0161-5505, 1535-5667electronic), 2004 Mar; 45(3): 485-494.

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* Criteria for the design and biological characterization of radiolabeled peptide-based pharmaceuticals (115 views)
Benedetti E, Morelli G, Accardo A, Mansi R, Tesauro D, Aloj L
Biodrugs (ISSN: 1173-8804), 2004; 18(5): 279-295.

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* Peptide-chelating agent conjugate for selective targeting of somatostatin receptor type 1: Synthesis and characterization (49 views)
Mansi R, Tesauro D, De Capua A, Fattorusso R, Carac C, Aloj L, Benedetti E, Morelli G
Biopolymers (ISSN: 0006-3525, 0006-6352, 0006-3525print), 2004; 76(6): 527-534.

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* The DICOM file format: postprocessing features in MRI (73 views)
Larobina M
Physica Medica (ISSN: 1120-1797), 2003 Oct; 19(4): 305-307.

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* Nuclear medicine and positron emission tomography imaging in cardiology (105 views)
Cuocolo A, Acampa W, Evangelista L
Nucl Med Rev (ISSN: 1506-9680), 2003; 6(1): 59-63.

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* Nuclear medicine procedures in cardiovascular diseases: An evidence based approach (105 views)
Acampa W, Petretta M, Cuocolo A
Association Of Radiopharmacology (ISSN: 1124-3937, 1125-0135), 2002 Dec; 46(4): 323-330.

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* New frontiers of nuclear medicine (68 views)
Salvatore M, Fonti R
Tumori (ISSN: 0300-8916, 0300-8916print), 2002 May; 88(3): S60-S60.

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Dynamic imaging: Scintimammography (81 views)
Salvatore M, Del Vecchio S
Eur J Radiol Elsevier Sci Ireland Ltd (ISSN: 0720-048x), 1998 May; 27(SUPPL.2): S259-S259.

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Single tube gamma camera for scintimammography (61 views)
Pani R, Scopinaro F, Pellegrini R, Soluri A, Pergola A, De Vincentis G, Ierardi M, Weinberg IN
Anticancer Research (ISSN: 0250-7005, 0250-0700), 1997 May; 17(3B): 1651-1654.

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Role Of Nuclear Cardiology For Guiding Device Therapy In Patients With Heart Failure (58 views)
Petretta M, Petretta A, Pellegrino T, Nappi C, Cantoni V, Cuocolo A
Curr Cardiovasc Imaging Rep (ISSN: 1941-9066), N/D; 2(1): 16-16.

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65 Records (59 excluding Abstracts and Conferences).
Total impact factor: 200.861 (187.964 excluding Abstracts and Conferences).
Total 5-year impact factor: 197.284 (184.481 excluding Abstracts and Conferences).



Your bibliography query: (([btitle, keywords, abstract] NUCLEAR AND [btitle, keywords, abstract] MEDICINE AND [btitle, keywords, abstract] IMAGING)) AND NOT [id] = 53292



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