In Vivo Imaging of Tumor Metabolism and Acidosis by Combining PET and MRI-CEST pH Imaging (233 views)
Cancer Res (ISSN: 0008-5472, 1538-7445, 0008-5472linking), 2016 Nov 15; 76(22): 6463-6470.
Export to BibTeX Export to EndNote
Paper type: Journal Article, Research Support, Non-U. S. Gov'T,
Impact factor: 9.122, 5-year impact factor: 9.826
Url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84995495851&doi=10.1158%2f0008-5472.CAN-16-0825&partnerID=40&md5=c657aa7ec66ed9025e45421194c3c5cb
Keywords: Acidosis , Humans , Magnetic Resonance Imaging Methods , Neoplasms Metabolism , Positron Emission Tomography Computed Tomography Methods,
Affiliations:
*** IBB - CNR ***
Institute of Biostructure and Bioimaging (CNR) c/o Molecular Biotechnologies Center, Torino, Italy., Molecular Imaging Center, University of Torino, Torino, Italy., Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy., Department of Nuclear Medicine, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany., Molecular Imaging Center, University of Torino, Torino, Italy. silvio.aime@unito.it.,
Molecular Imaging Center, University of Torino, Torino, Italy.
Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy.
Department of Nuclear Medicine, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany.
References:
Not available.
Cancer Res (ISSN: 0008-5472, 1538-7445, 0008-5472linking), 2016 Nov 15; 76(22): 6463-6470.
Export to BibTeX Export to EndNote
Paper type: Journal Article, Research Support, Non-U. S. Gov'T,
Impact factor: 9.122, 5-year impact factor: 9.826
Url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84995495851&doi=10.1158%2f0008-5472.CAN-16-0825&partnerID=40&md5=c657aa7ec66ed9025e45421194c3c5cb
Keywords: Acidosis , Humans , Magnetic Resonance Imaging Methods , Neoplasms Metabolism , Positron Emission Tomography Computed Tomography Methods,
Affiliations:
*** IBB - CNR ***
Institute of Biostructure and Bioimaging (CNR) c/o Molecular Biotechnologies Center, Torino, Italy., Molecular Imaging Center, University of Torino, Torino, Italy., Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy., Department of Nuclear Medicine, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany., Molecular Imaging Center, University of Torino, Torino, Italy. silvio.aime@unito.it.,
Molecular Imaging Center, University of Torino, Torino, Italy.
Department of Molecular Biotechnology and Health Sciences, University of Torino, Torino, Italy.
Department of Nuclear Medicine, Klinikum rechts der Isar, Technische Universitat Munchen, Munich, Germany.
References:
Not available.
In Vivo Imaging of Tumor Metabolism and Acidosis by Combining PET and MRI-CEST pH Imaging
The vast majority of cancers exhibit increased glucose uptake and glycolysis regardless of oxygen availability. This metabolic shift leads to an enhanced production of lactic acid that decreases extracellular pH (pHe), a hallmark of the tumor microenvironment. In this way, dysregulated tumor pHe and upregulated glucose metabolism are linked tightly and their relative assessment may be useful to gain understanding of the underlying biology. Here we investigated noninvasively the in vivo correlation between tumor (18)F-FDG uptake and extracellular pH values in a murine model of HER2(+) breast cancer. Tumor extracellular pH and perfusion were assessed by acquiring MRI-CEST (chemical exchange saturation transfer) images on a 3T scanner after intravenous administration of a pH-responsive contrast agent (iopamidol). Static PET images were recorded immediately after MRI acquisitions to quantify the extent of (18)F-FDG uptake. We demonstrated the occurrence of tumor pHe changes that report on acidification of the interstitial fluid caused by an accelerated glycolysis. Combined PET and MRI-CEST images reported complementary spatial information of the altered glucose metabolism. Notably, a significant inverse correlation was found between extracellular tumor pH and (18)F-FDG uptake, as a high (18)F-FDG uptake corresponds to lower extracellular pH values. These results show how merging the information from (18)F-FDG-uptake and extracellular pH measurements can improve characterization of the tumor microenvironment. Cancer Res; 76(22); 6463-70. ©2016 AACR.
The vast majority of cancers exhibit increased glucose uptake and glycolysis regardless of oxygen availability. This metabolic shift leads to an enhanced production of lactic acid that decreases extracellular pH (pHe), a hallmark of the tumor microenvironment. In this way, dysregulated tumor pHe and upregulated glucose metabolism are linked tightly and their relative assessment may be useful to gain understanding of the underlying biology. Here we investigated noninvasively the in vivo correlation between tumor (18)F-FDG uptake and extracellular pH values in a murine model of HER2(+) breast cancer. Tumor extracellular pH and perfusion were assessed by acquiring MRI-CEST (chemical exchange saturation transfer) images on a 3T scanner after intravenous administration of a pH-responsive contrast agent (iopamidol). Static PET images were recorded immediately after MRI acquisitions to quantify the extent of (18)F-FDG uptake. We demonstrated the occurrence of tumor pHe changes that report on acidification of the interstitial fluid caused by an accelerated glycolysis. Combined PET and MRI-CEST images reported complementary spatial information of the altered glucose metabolism. Notably, a significant inverse correlation was found between extracellular tumor pH and (18)F-FDG uptake, as a high (18)F-FDG uptake corresponds to lower extracellular pH values. These results show how merging the information from (18)F-FDG-uptake and extracellular pH measurements can improve characterization of the tumor microenvironment. Cancer Res; 76(22); 6463-70. ©2016 AACR.
In Vivo Imaging of Tumor Metabolism and Acidosis by Combining PET and MRI-CEST pH Imaging
No results. |
In Vivo Imaging of Tumor Metabolism and Acidosis by Combining PET and MRI-CEST pH Imaging
Other filter: ([btitle,keywords] "Magnetic Resonance I ...
Platella C, Gaglione R, Napolitano E, Arciello A, Pirota V, Doria F, Musumeci D, Montesarchio D
* DNA Binding Mode Analysis of a Core-Extended Naphthalene Diimide as a Conformation-Sensitive Fluorescent Probe of G-Quadruplex Structures (7 views)
Int J Mol Sci (ISSN: 1422-0067linking), 2021 Sep 30; 22 (19 ): N/D-N/D.
Impact Factor:
View Export to BibTeX Export to EndNote
Larobina M, Megna R, Solla R
* Comparison of three freeware software packages for (18)F-FDG PET texture feature calculation (57 views)
Jpn J Radiol (ISSN: 1867-1071linking), 2021 Jul; 39(7): 710-719.
Impact Factor: 1.439
View Export to BibTeX Export to EndNote
Mainenti PP, Castiglione F, Rispo A, Laccetti E, Guarino S, Romeo V, Testa A, Pace L, Maurea S
* MR-enterography in Crohn's disease: what MRE mural parameters are associated to one-year therapeutic management outcome? (42 views)
Br J Radiol (ISSN: 0007-1285linking, 1748-880xelectronic), 2021 Feb 1; 94(1118): 20200844-20200844.
Impact Factor: 2.196
View Export to BibTeX Export to EndNote
Brancato V, Aiello M, Basso L, Monti S, Palumbo L, Di Costanzo G, Salvatore M, Ragozzino A, Cavaliere C
* Evaluation of a multiparametric MRI radiomic-based approach for stratification of equivocal PI-RADS 3 and upgraded PI-RADS 4 prostatic lesions (68 views)
Sci Rep (ISSN: 2045-2322linking, 2045-2322electronic), 2021 Jan 12; 11(1): 643-643.
Impact Factor: 4.379
View Export to BibTeX Export to EndNote
Anemone A, Consolino L, Conti L, Irrera P, Hsu MY, Villano D, Dastrù W, Porporato PE, Cavallo F, Longo DL
* Tumour acidosis evaluated in vivo by MRI-CEST pH imaging reveals breast cancer metastatic potential (65 views)
Br J Cancer (ISSN: 0007-0920linking, 0007-0920print), 2021 Jan; 124(1): 207-216.
Impact Factor: 5.49
View Export to BibTeX Export to EndNote
Zöllner FG, Dastrù W, Irrera P, Longo DL, Bennett KM, Beeman SC, Bretthorst GL, Garbow JR
* Analysis Protocol for Dynamic Contrast Enhanced (DCE) MRI of Renal Perfusion and Filtration (18 views)
Methods Mol Biol (ISSN: 1064-3745linking, 1940-6029electronic), 2021; 2216: 637-653.
Impact Factor: 1.17
View Export to BibTeX Export to EndNote
Kim H, Wu Y, Villano D, Longo DL, Mcmahon MT, Sun PZ
* Analysis Protocol for the Quantification of Renal pH Using Chemical Exchange Saturation Transfer (CEST) MRI (21 views)
Methods Mol Biol (ISSN: 1064-3745linking, 1940-6029electronic), 2021; 2216: 667-688.
Impact Factor: 1.17
View Export to BibTeX Export to EndNote
Irrera P, Consolino L, Dastrù W, Pedersen M, Zöllner FG, Longo DL
* Dynamic Contrast Enhanced (DCE) MRI-Derived Renal Perfusion and Filtration: Experimental Protocol (12 views)
Methods Mol Biol (ISSN: 1064-3745linking, 1940-6029electronic), 2021; 2216: 429-441.
Impact Factor: 1.17
View Export to BibTeX Export to EndNote
Pedersen M, Irrera P, Dastrù W, Zöllner FG, Bennett KM, Beeman SC, Bretthorst GL, Garbow JR, Longo DL
* Dynamic Contrast Enhancement (DCE) MRI-Derived Renal Perfusion and Filtration: Basic Concepts (16 views)
Methods Mol Biol (ISSN: 1064-3745linking, 1940-6029electronic), 2021; 2216: 205-227.
Impact Factor: 1.17
View Export to BibTeX Export to EndNote
Pohlmann A, Back SJ, Fekete A, Friedli I, Hectors S, Jerome NP, Ku MC, Longo DL, Meier M, Millward JM, Periquito JS, Seeliger E, Serai SD, Waiczies S, Sourbron S, Laustsen C, Niendorf T
* Recommendations for Preclinical Renal MRI: A Comprehensive Open-Access Protocol Collection to Improve Training, Reproducibility, and Comparability of Studies (11 views)
Methods Mol Biol (ISSN: 1064-3745linking, 1940-6029electronic), 2021; 2216: 3-23.
Impact Factor: 1.17
View Export to BibTeX Export to EndNote
Longo DL, Irrera P, Consolino L, Sun PZ, Mcmahon MT
* Renal pH Imaging Using Chemical Exchange Saturation Transfer (CEST) MRI: Basic Concept (36 views)
Methods Mol Biol (ISSN: 1064-3745linking, 1940-6029electronic), 2021; 2216: 241-256.
Impact Factor: 1.17
View Export to BibTeX Export to EndNote
Pavuluri KD, Consolino L, Longo DL, Irrera P, Sun PZ, Mcmahon MT
* Renal pH Mapping Using Chemical Exchange Saturation Transfer (CEST) MRI: Experimental Protocol (9 views)
Methods Mol Biol (ISSN: 1064-3745linking, 1940-6029electronic), 2021; 2216: 455-471.
Impact Factor: 1.17
View Export to BibTeX Export to EndNote
Pontillo G, Cocozza S, Di Stasi M, Carotenuto A, Paolella C, Cipullo MB, Perillo T, Vola EA, Russo C, Masullo M, Moccia M, Lanzillo R, Tedeschi E, Elefante A, Brescia Morra V, Brunetti A, Quarantelli M, Petracca M
* 2D linear measures of ventricular enlargement may be relevant markers of brain atrophy and long-term disability progression in multiple sclerosis (135 views)
Eur Radiol (ISSN: 0938-7994linking, 1432-1084electronic), 2020 Jul; 30(7): 3813-3822.
Impact Factor: 4.101
View Export to BibTeX Export to EndNote
Tear LR, Carrera C, Gianolio E, Aime S
* Towards an Improved Design of MRI Contrast Agents: Synthesis and Relaxometric Characterisation of Gd-HPDO3A Analogues (60 views)
Chemistry (ISSN: 0947-6539linking, 1521-3765electronic), 2020 May 12; 26(27): 6056-6063.
Impact Factor: 4.857
View Export to BibTeX Export to EndNote
Romeo V, Ricciardi C, Cuocolo R, Stanzione A, Verde F, Sarno L, Improta G, Mainenti PP, D'Armiento M, Brunetti A, Maurea S
* Machine learning analysis of MRI-derived texture features to predict placenta accreta spectrum in patients with placenta previa (70 views)
Magn Reson Imaging (ISSN: 0730-725xlinking), 2019 Dec; 64: 71-76.
Impact Factor: 2.037
View Export to BibTeX Export to EndNote
Romeo V, Sarno L, Volpe A, Ginocchio MI, Esposito R, Mainenti PP, Petretta M, Liuzzi R, D'Armiento M, Martinelli P, Brunetti A, Maurea S
* US and MR imaging findings to detect placental adhesion spectrum (PAS) in patients with placenta previa: a comparative systematic study (85 views)
Abdom Radiol (ISSN: 2366-0058electronic, 2366-004xprint), 2019 Oct; 44(10): 3398-3407.
Impact Factor: 2.147
View Export to BibTeX Export to EndNote
De Michele G, Lieto M, Galatolo D, Salvatore E, Cocozza S, Barghigiani M, Tessa A, Baldacci J, Pappata S, Filla A, De Michele G, Santorelli FM
* Spinocerebellar ataxia 48 presenting with ataxia associated with cognitive, psychiatric, and extrapyramidal features: A report of two Italian families (170 views)
Parkinsonism Relat D (ISSN: 1353-8020linking, 1353-8020print), 2019 May 14; 65: 91-96.
Impact Factor: 4.721
View Export to BibTeX Export to EndNote
Kujawa A, Kim M, Demetriou E, Anemone A, Livio Longo D, Zaiss M, Golay X
* Assessment of a clinically feasible Bayesian fitting algorithm using a simplified description of Chemical Exchange Saturation Transfer (CEST) imaging (23 views)
J Magn Reson (ISSN: 1090-7807linking), 2019 Mar; 300: 120-134.
Impact Factor: 2.586
View Export to BibTeX Export to EndNote
Megna R, Alfano B, Lanzillo R, Costabile T, Comerci M, Vacca G, Carotenuto A, Moccia M, Servillo G, Prinster A, Brescia Morra V, Quarantelli M
* Brain tissue volumes and relaxation rates in multiple sclerosis: implications for cognitive impairment (265 views) (PDF 10 views)
J Neurol (ISSN: 1432-1459electronic, 0340-5354linking, 0340-5354print), 2019 Feb; 266(2): 361-368.
Impact Factor: 3.853
View Export to BibTeX Export to EndNote
Cocozza S, Pontillo G, Lanzillo R, Russo C, Petracca M, Di Stasi M, Paolella C, Vola EA, Criscuolo C, Moccia M, Lamberti A, Monti S, Brescia Morra V, Elefante A, Palma G, Tedeschi E, Brunetti A
* MRI features suggestive of gadolinium retention do not correlate with Expanded Disability Status Scale worsening in Multiple Sclerosis (271 views)
Neuroradiology (ISSN: 0028-3940linking, 1432-1920electronic), 2019 Feb; 61(2): 155-162.
Impact Factor: 1.287
View Export to BibTeX Export to EndNote
Melillo P, Prinster A, Di Iorio V, Olivo G, D'Alterio FM, Cocozza S, Orrico A, Quarantelli M, Testa F, Brunetti A, Simonelli F
* Visual Cortex Activation in Patients With Stargardt Disease (245 views)
Invest Ophth Vis Sci (ISSN: 0146-0404linking, 1552-5783electronic), 2018 Mar 1; 59(3): 1503-1511.
Impact Factor: 3.303
View Export to BibTeX Export to EndNote
Monti S, Borrelli P, Tedeschi E, Cocozza S, Palma G
* RESUME: Turning an SWI acquisition into a fast qMRI protocol (330 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2017 Dec 20; 12(12): e0189933-e0189933.
Impact Factor: 2.766
View Export to BibTeX Export to EndNote
Longo DL, Aime S
* A generalized ratiometric chemical exchange saturation transfer (CEST) MRI approach for mapping renal pH using iopamidol (215 views)
Magn Reson Med (ISSN: 0740-3194, 1522-2594electronic, 0740-3194linking), 2017 Jul 07; 79(3): 1553-1558.
Impact Factor: 4.082
View Export to BibTeX Export to EndNote
Canna A, Prinster A, Monteleone AM, Cantone E, Monteleone P, Volpe U, Maj M, Di Salle F, Esposito F
* Interhemispheric Functional Connectivity in Anorexia and Bulimia Nervosa (248 views)
Eur J Neurosci (ISSN: 0953-816x), 2017 May; 45(9): 1129-1140.
Impact Factor: 2.832
View Export to BibTeX Export to EndNote
Segreto S, Fonti R, Ottaviano M, Pellegrino S, Pace L, Damiano V, Palmieri G, Del Vecchio S
* Evaluation of metabolic response with (18)F-FDG PET-CT in patients with advanced or recurrent thymic epithelial tumors (232 views)
Cancer Imaging (ISSN: 1470-7330, 1470-7330electronic), 2017 Mar 7; 17(1): 10-10.
Impact Factor: 3.016
View Export to BibTeX Export to EndNote
Consolino L, Longo DL, Sciortino M, Dastru W, Cabodi S, Giovenzana GB, Aime S
* Assessing tumor vascularization as a potential biomarker of imatinib resistance in gastrointestinal stromal tumors by dynamic contrast-enhanced magnetic resonance imaging (238 views)
Gastric Cancer (ISSN: 1436-3291, 1436-3291linking), 2016 Dec 19; 20(4): 629-639.
Impact Factor: 5.454
View Export to BibTeX Export to EndNote
Lastoria S, Marciello F, Faggiano A, Aloj L, Caraco C, Aurilio M, D'Ambrosio L, Di Gennaro F, Ramundo V, Camera L, De LucaL, Fonti R, Napolitano V, Colao A
* Role of (68)Ga-DOTATATE PET/CT in patients with multiple endocrine neoplasia type 1 (MEN1) (231 views)
Endocrine (ISSN: 1355-008x), 2016 Jun; 52(3): 488-494.
Impact Factor: 3.131
View Export to BibTeX Export to EndNote
Mainenti PP, Pizzuti LM, Segreto S, Comerci M, Fronzo SD, Romano F, Crisci V, Smaldone M, Laccetti E, Storto G, Alfano B, Maurea S, Salvatore M, Pace L
* Diffusion volume (DV) measurement in endometrial and cervical cancer: A new MRI parameter in the evaluation of the tumor grading and the risk classification (884 views) (PDF 235 views)
Eur J Radiol (ISSN: 0720-048x, 0720-048xlinking), 2016 Jan; 85(1): 113-124.
Impact Factor: 2.462
View Export to BibTeX Export to EndNote
Palma G, Tedeschi E, Borrelli P, Cocozza S, Russo C, Liu S, Ye Y, Comerci M, Alfano B, Salvatore M, Haacke EM, Mancini M
* A Novel Multiparametric Approach to 3D Quantitative MRI of the Brain (605 views) (PDF 256 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2015 Aug 18; 10(8): e0134963-e0134963.
Impact Factor: 3.057
View Export to BibTeX Export to EndNote
Conson M, Cella L, Pacelli R, Comerci M, Liuzzi R, Salvatore M, Quarantelli M
* Automated delineation of brain structures in patients undergoing radiotherapy for primary brain tumors: From atlas to dose-volume histograms (760 views) (PDF 368 views)
Radiother Oncol (ISSN: 0167-8140, 1879-0887, 0167-8140linking), 2014 Sep; 112(3): 326-331.
Impact Factor: 4.363
View Export to BibTeX Export to EndNote
D'Alterio C, Avallone A, Tatangelo F, Delrio P, Pecori B, Cella L, Pelella A, D'Armiento FP, Carlomagno C, Bianco F, Silvestro L, Pacelli R, Napolitano M, Iaffaioli RV, Scala S
* A prognostic model comprising pT stage, N status, and the chemokine receptors CXCR4 and CXCR7 powerfully predicts outcome in neoadjuvant resistant rectal cancer patients (385 views)
Int J Cancer (ISSN: 0020-7136), 2014 Jul 15; 135(2): 379-390.
Impact Factor: 5.085
View Export to BibTeX Export to EndNote
Murino L, Granata D, Carfora MF, Selvan SE, Alfano B, Amato U, Larobina M
* Evaluation of supervised methods for the classification of major tissues and subcortical structures in multispectral brain magnetic resonance images (441 views) (PDF 222 views)
Comput Med Imag Grap (ISSN: 0895-6111), 2014 Jul; 38(5): 337-347.
Impact Factor: 1.218
View Export to BibTeX Export to EndNote
Iodice D, Di Donato O, Liccardo I, Lamanna L, Segreto S, Salvatore M, Imbriaco M
* Prevalence of extramammary findings on breast MRI: a large retrospective single-centre study (328 views)
Radiol Med (ISSN: 1826-6983, 0033-8362, 1826-6983electronic), 2013 Oct; 118(7): 1109-1118.
Impact Factor: 1.368
View Export to BibTeX Export to EndNote
Mancini M, Greco A, Salvatore G, Liuzzi R, Di Maro G, Vergara E, Chiappetta G, Pasquinelli R, Brunetti A, Salvatore M
* Imaging of thyroid tumor angiogenesis with microbubbles targeted to vascular endothelial growth factor receptor type 2 in mice (448 views)
Bmc Med Imaging (ISSN: 1471-2342, 1471-2342electronic), 2013 Sep 12; 13(1): 31-31.
Impact Factor: 0.983
View Export to BibTeX Export to EndNote
Comerci M, Elefante A, Strianese D, Senese R, Bonavolonta P, Alfano B, Bonavolonta B, Brunetti A
* Semiautomatic regional segmentation to measure orbital fat volumes in thyroid-associated ophthalmopathy. A validation study (463 views) (PDF 251 views)
Neuroradiol J (ISSN: 1971-4009, 1971-4009print, 1971-4009linking), 2013 Aug; 26(4): 373-379.
Impact Factor: 2.16
View Export to BibTeX Export to EndNote
Risitano AM, Imbriaco M, Marando L, Seneca E, Soscia E, Malcovati L, Iori AP, Pane F, Notaro R, Matarazzo M
* From perpetual haemosiderinuria to possible iron overload: iron redistribution in paroxysmal nocturnal haemoglobinuria patients on eculizumab by magnetic resonance imaging (325 views)
Br J Haematol (ISSN: 0007-1048, 0007-1048linking, 1365-2141electronic), 2012 Sep; 158(3): 415-418.
Impact Factor: 4.942
View Export to BibTeX Export to EndNote
Digilio G, Menchise V, Gianolio E, Catanzaro V, Carrera C, Napolitano R, Fedeli F, Aime S
* Exofacial protein thiols as a route for the internalization of Gd(III)-based complexes for magnetic resonance imaging cell labeling (440 views)
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2010 Jul 8; 53(13): 4877-4890.
Impact Factor: 5.207
View Export to BibTeX Export to EndNote
Digilio G, Catanzaro V, Fedeli F, Gianolio E, Menchise V, Napolitano R, Gringeri C, Aime S
* Targeting exofacial protein thiols with Gd-III complexes. An efficient procedure for MRI cell labelling (323 views)
Chem Commun (ISSN: 1359-7345, 1364-548x, 1364-548xelectronic), 2009 Feb 28; (8): 893-895.
Impact Factor: 5.504
View Export to BibTeX Export to EndNote
Tedeschi G, Dinacci D, Lavorgna L, Prinster A, Savettieri G, Quattrone A, Livrea P, Messina C, Reggio A, Servillo G, Bresciamorra V, Orefice G, Paciello M, Brunetti A, Paolillo A, Coniglio G, Bonavita S, Di Costanzo A, Bellacosa A, Valentino P, Quarantelli M, Patti F, Salemi G, Cammarata E, Simone I, Salvatore M, Bonavita V, Alfano B
* Correlation between fatigue and brain atrophy and lesion load in multiple sclerosis patients independent of disability (499 views) (PDF 237 views)
J Neurol Sci (ISSN: 0022-510x), 2007 Dec 15; 263(1-2): 15-19.
Impact Factor: 2.315
View Export to BibTeX Export to EndNote
Amato U, Larobina M, Antoniadis A, Alfano B
* Segmentation of magnetic resonance brain images through discriminant analysis (554 views) (PDF 239 views)
J Neurosci Methods (ISSN: 0165-0270, 0165-0270linking, 1872-678xelectronic), 2003 Dec 30; 131(1-2): 65-74.
Impact Factor: 1.777
View Export to BibTeX Export to EndNote
Quarantelli M, Larobina M, Volpe U, Amati G, Tedeschi E, Ciarmiello A, Brunetti A, Galderisi S, Alfano B
* Stereotaxy-based regional brain volumetry applied to segmented MRI: Validation and results in deficit and nondeficit schizophrenia (364 views) (PDF 205 views)
Neuroimage (ISSN: 1053-8119, 1053-8119linking), 2002 Sep; 17(1): 373-384.
Impact Factor: 5.624
View Export to BibTeX Export to EndNote
Alfano B, Quarantelli M, Brunetti A, Larobina M, Covelli EM, Tedeschi E, Salvatore M
Reproducibility of intracranial volume measurement by unsupervised multispectral brain segmentation (500 views) (PDF 592 views)
Magn Reson Med (ISSN: 0740-3194, 1522-2594electronic, 0740-3194linking), 1998 Mar; 39(3): 497-499.
Impact Factor: 2.962
View Export to BibTeX Export to EndNote
Alfano B, Brunetti A, Covelli EM, Quarantelli M, Panico M, Ciarmiello A, Salvatore M
Unsupervised, automated segmentation of the normal brain using a multispectral relaxometric magnetic resonance approach (494 views) (PDF 686 views)
Magn Reson Med (ISSN: 0740-3194, 1522-2594electronic, 0740-3194linking), 1997 Jan; 37(1): 84-93.
Impact Factor: 3.012
View Export to BibTeX Export to EndNote
Caraglia M, Tagliaferri P, Correale P, Genua G, Pinto A, Del Vecchio S, Esposito G, Bianco AR
Cytosine arabinoside increases the binding of 125I-labelled epidermal growth factor and 125I-transferrin and enhances the in vitro targeting of human tumour cells with anti-(growth factor receptor) mAb (225 views)
Cancer Immunol Immunother (ISSN: 0340-7004linking), 1993 Aug; 37 (3 ): 150-156.
Impact Factor: 4.293
View Export to BibTeX Export to EndNote
Alfano B, Brunetti A, Ciarmiello A, Salvatore M
Simultaneous display of multiple MR parameters with 'quantitative magnetic color imaging' (335 views) (PDF 639 views)
J Comput Assisted Tomogr (ISSN: 0363-8715), 1992 Jul; 16(4): 634-640.
Impact Factor: 1.263
View Export to BibTeX Export to EndNote
* DNA Binding Mode Analysis of a Core-Extended Naphthalene Diimide as a Conformation-Sensitive Fluorescent Probe of G-Quadruplex Structures (7 views)
Int J Mol Sci (ISSN: 1422-0067linking), 2021 Sep 30; 22 (19 ): N/D-N/D.
Impact Factor:
View Export to BibTeX Export to EndNote
Larobina M, Megna R, Solla R
* Comparison of three freeware software packages for (18)F-FDG PET texture feature calculation (57 views)
Jpn J Radiol (ISSN: 1867-1071linking), 2021 Jul; 39(7): 710-719.
Impact Factor: 1.439
View Export to BibTeX Export to EndNote
Mainenti PP, Castiglione F, Rispo A, Laccetti E, Guarino S, Romeo V, Testa A, Pace L, Maurea S
* MR-enterography in Crohn's disease: what MRE mural parameters are associated to one-year therapeutic management outcome? (42 views)
Br J Radiol (ISSN: 0007-1285linking, 1748-880xelectronic), 2021 Feb 1; 94(1118): 20200844-20200844.
Impact Factor: 2.196
View Export to BibTeX Export to EndNote
Brancato V, Aiello M, Basso L, Monti S, Palumbo L, Di Costanzo G, Salvatore M, Ragozzino A, Cavaliere C
* Evaluation of a multiparametric MRI radiomic-based approach for stratification of equivocal PI-RADS 3 and upgraded PI-RADS 4 prostatic lesions (68 views)
Sci Rep (ISSN: 2045-2322linking, 2045-2322electronic), 2021 Jan 12; 11(1): 643-643.
Impact Factor: 4.379
View Export to BibTeX Export to EndNote
Anemone A, Consolino L, Conti L, Irrera P, Hsu MY, Villano D, Dastrù W, Porporato PE, Cavallo F, Longo DL
* Tumour acidosis evaluated in vivo by MRI-CEST pH imaging reveals breast cancer metastatic potential (65 views)
Br J Cancer (ISSN: 0007-0920linking, 0007-0920print), 2021 Jan; 124(1): 207-216.
Impact Factor: 5.49
View Export to BibTeX Export to EndNote
Zöllner FG, Dastrù W, Irrera P, Longo DL, Bennett KM, Beeman SC, Bretthorst GL, Garbow JR
* Analysis Protocol for Dynamic Contrast Enhanced (DCE) MRI of Renal Perfusion and Filtration (18 views)
Methods Mol Biol (ISSN: 1064-3745linking, 1940-6029electronic), 2021; 2216: 637-653.
Impact Factor: 1.17
View Export to BibTeX Export to EndNote
Kim H, Wu Y, Villano D, Longo DL, Mcmahon MT, Sun PZ
* Analysis Protocol for the Quantification of Renal pH Using Chemical Exchange Saturation Transfer (CEST) MRI (21 views)
Methods Mol Biol (ISSN: 1064-3745linking, 1940-6029electronic), 2021; 2216: 667-688.
Impact Factor: 1.17
View Export to BibTeX Export to EndNote
Irrera P, Consolino L, Dastrù W, Pedersen M, Zöllner FG, Longo DL
* Dynamic Contrast Enhanced (DCE) MRI-Derived Renal Perfusion and Filtration: Experimental Protocol (12 views)
Methods Mol Biol (ISSN: 1064-3745linking, 1940-6029electronic), 2021; 2216: 429-441.
Impact Factor: 1.17
View Export to BibTeX Export to EndNote
Pedersen M, Irrera P, Dastrù W, Zöllner FG, Bennett KM, Beeman SC, Bretthorst GL, Garbow JR, Longo DL
* Dynamic Contrast Enhancement (DCE) MRI-Derived Renal Perfusion and Filtration: Basic Concepts (16 views)
Methods Mol Biol (ISSN: 1064-3745linking, 1940-6029electronic), 2021; 2216: 205-227.
Impact Factor: 1.17
View Export to BibTeX Export to EndNote
Pohlmann A, Back SJ, Fekete A, Friedli I, Hectors S, Jerome NP, Ku MC, Longo DL, Meier M, Millward JM, Periquito JS, Seeliger E, Serai SD, Waiczies S, Sourbron S, Laustsen C, Niendorf T
* Recommendations for Preclinical Renal MRI: A Comprehensive Open-Access Protocol Collection to Improve Training, Reproducibility, and Comparability of Studies (11 views)
Methods Mol Biol (ISSN: 1064-3745linking, 1940-6029electronic), 2021; 2216: 3-23.
Impact Factor: 1.17
View Export to BibTeX Export to EndNote
Longo DL, Irrera P, Consolino L, Sun PZ, Mcmahon MT
* Renal pH Imaging Using Chemical Exchange Saturation Transfer (CEST) MRI: Basic Concept (36 views)
Methods Mol Biol (ISSN: 1064-3745linking, 1940-6029electronic), 2021; 2216: 241-256.
Impact Factor: 1.17
View Export to BibTeX Export to EndNote
Pavuluri KD, Consolino L, Longo DL, Irrera P, Sun PZ, Mcmahon MT
* Renal pH Mapping Using Chemical Exchange Saturation Transfer (CEST) MRI: Experimental Protocol (9 views)
Methods Mol Biol (ISSN: 1064-3745linking, 1940-6029electronic), 2021; 2216: 455-471.
Impact Factor: 1.17
View Export to BibTeX Export to EndNote
Pontillo G, Cocozza S, Di Stasi M, Carotenuto A, Paolella C, Cipullo MB, Perillo T, Vola EA, Russo C, Masullo M, Moccia M, Lanzillo R, Tedeschi E, Elefante A, Brescia Morra V, Brunetti A, Quarantelli M, Petracca M
* 2D linear measures of ventricular enlargement may be relevant markers of brain atrophy and long-term disability progression in multiple sclerosis (135 views)
Eur Radiol (ISSN: 0938-7994linking, 1432-1084electronic), 2020 Jul; 30(7): 3813-3822.
Impact Factor: 4.101
View Export to BibTeX Export to EndNote
Tear LR, Carrera C, Gianolio E, Aime S
* Towards an Improved Design of MRI Contrast Agents: Synthesis and Relaxometric Characterisation of Gd-HPDO3A Analogues (60 views)
Chemistry (ISSN: 0947-6539linking, 1521-3765electronic), 2020 May 12; 26(27): 6056-6063.
Impact Factor: 4.857
View Export to BibTeX Export to EndNote
Romeo V, Ricciardi C, Cuocolo R, Stanzione A, Verde F, Sarno L, Improta G, Mainenti PP, D'Armiento M, Brunetti A, Maurea S
* Machine learning analysis of MRI-derived texture features to predict placenta accreta spectrum in patients with placenta previa (70 views)
Magn Reson Imaging (ISSN: 0730-725xlinking), 2019 Dec; 64: 71-76.
Impact Factor: 2.037
View Export to BibTeX Export to EndNote
Romeo V, Sarno L, Volpe A, Ginocchio MI, Esposito R, Mainenti PP, Petretta M, Liuzzi R, D'Armiento M, Martinelli P, Brunetti A, Maurea S
* US and MR imaging findings to detect placental adhesion spectrum (PAS) in patients with placenta previa: a comparative systematic study (85 views)
Abdom Radiol (ISSN: 2366-0058electronic, 2366-004xprint), 2019 Oct; 44(10): 3398-3407.
Impact Factor: 2.147
View Export to BibTeX Export to EndNote
De Michele G, Lieto M, Galatolo D, Salvatore E, Cocozza S, Barghigiani M, Tessa A, Baldacci J, Pappata S, Filla A, De Michele G, Santorelli FM
* Spinocerebellar ataxia 48 presenting with ataxia associated with cognitive, psychiatric, and extrapyramidal features: A report of two Italian families (170 views)
Parkinsonism Relat D (ISSN: 1353-8020linking, 1353-8020print), 2019 May 14; 65: 91-96.
Impact Factor: 4.721
View Export to BibTeX Export to EndNote
Kujawa A, Kim M, Demetriou E, Anemone A, Livio Longo D, Zaiss M, Golay X
* Assessment of a clinically feasible Bayesian fitting algorithm using a simplified description of Chemical Exchange Saturation Transfer (CEST) imaging (23 views)
J Magn Reson (ISSN: 1090-7807linking), 2019 Mar; 300: 120-134.
Impact Factor: 2.586
View Export to BibTeX Export to EndNote
Megna R, Alfano B, Lanzillo R, Costabile T, Comerci M, Vacca G, Carotenuto A, Moccia M, Servillo G, Prinster A, Brescia Morra V, Quarantelli M
* Brain tissue volumes and relaxation rates in multiple sclerosis: implications for cognitive impairment (265 views) (PDF 10 views)
J Neurol (ISSN: 1432-1459electronic, 0340-5354linking, 0340-5354print), 2019 Feb; 266(2): 361-368.
Impact Factor: 3.853
View Export to BibTeX Export to EndNote
Cocozza S, Pontillo G, Lanzillo R, Russo C, Petracca M, Di Stasi M, Paolella C, Vola EA, Criscuolo C, Moccia M, Lamberti A, Monti S, Brescia Morra V, Elefante A, Palma G, Tedeschi E, Brunetti A
* MRI features suggestive of gadolinium retention do not correlate with Expanded Disability Status Scale worsening in Multiple Sclerosis (271 views)
Neuroradiology (ISSN: 0028-3940linking, 1432-1920electronic), 2019 Feb; 61(2): 155-162.
Impact Factor: 1.287
View Export to BibTeX Export to EndNote
Melillo P, Prinster A, Di Iorio V, Olivo G, D'Alterio FM, Cocozza S, Orrico A, Quarantelli M, Testa F, Brunetti A, Simonelli F
* Visual Cortex Activation in Patients With Stargardt Disease (245 views)
Invest Ophth Vis Sci (ISSN: 0146-0404linking, 1552-5783electronic), 2018 Mar 1; 59(3): 1503-1511.
Impact Factor: 3.303
View Export to BibTeX Export to EndNote
Monti S, Borrelli P, Tedeschi E, Cocozza S, Palma G
* RESUME: Turning an SWI acquisition into a fast qMRI protocol (330 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2017 Dec 20; 12(12): e0189933-e0189933.
Impact Factor: 2.766
View Export to BibTeX Export to EndNote
Longo DL, Aime S
* A generalized ratiometric chemical exchange saturation transfer (CEST) MRI approach for mapping renal pH using iopamidol (215 views)
Magn Reson Med (ISSN: 0740-3194, 1522-2594electronic, 0740-3194linking), 2017 Jul 07; 79(3): 1553-1558.
Impact Factor: 4.082
View Export to BibTeX Export to EndNote
Canna A, Prinster A, Monteleone AM, Cantone E, Monteleone P, Volpe U, Maj M, Di Salle F, Esposito F
* Interhemispheric Functional Connectivity in Anorexia and Bulimia Nervosa (248 views)
Eur J Neurosci (ISSN: 0953-816x), 2017 May; 45(9): 1129-1140.
Impact Factor: 2.832
View Export to BibTeX Export to EndNote
Segreto S, Fonti R, Ottaviano M, Pellegrino S, Pace L, Damiano V, Palmieri G, Del Vecchio S
* Evaluation of metabolic response with (18)F-FDG PET-CT in patients with advanced or recurrent thymic epithelial tumors (232 views)
Cancer Imaging (ISSN: 1470-7330, 1470-7330electronic), 2017 Mar 7; 17(1): 10-10.
Impact Factor: 3.016
View Export to BibTeX Export to EndNote
Consolino L, Longo DL, Sciortino M, Dastru W, Cabodi S, Giovenzana GB, Aime S
* Assessing tumor vascularization as a potential biomarker of imatinib resistance in gastrointestinal stromal tumors by dynamic contrast-enhanced magnetic resonance imaging (238 views)
Gastric Cancer (ISSN: 1436-3291, 1436-3291linking), 2016 Dec 19; 20(4): 629-639.
Impact Factor: 5.454
View Export to BibTeX Export to EndNote
Lastoria S, Marciello F, Faggiano A, Aloj L, Caraco C, Aurilio M, D'Ambrosio L, Di Gennaro F, Ramundo V, Camera L, De LucaL, Fonti R, Napolitano V, Colao A
* Role of (68)Ga-DOTATATE PET/CT in patients with multiple endocrine neoplasia type 1 (MEN1) (231 views)
Endocrine (ISSN: 1355-008x), 2016 Jun; 52(3): 488-494.
Impact Factor: 3.131
View Export to BibTeX Export to EndNote
Mainenti PP, Pizzuti LM, Segreto S, Comerci M, Fronzo SD, Romano F, Crisci V, Smaldone M, Laccetti E, Storto G, Alfano B, Maurea S, Salvatore M, Pace L
* Diffusion volume (DV) measurement in endometrial and cervical cancer: A new MRI parameter in the evaluation of the tumor grading and the risk classification (884 views) (PDF 235 views)
Eur J Radiol (ISSN: 0720-048x, 0720-048xlinking), 2016 Jan; 85(1): 113-124.
Impact Factor: 2.462
View Export to BibTeX Export to EndNote
Palma G, Tedeschi E, Borrelli P, Cocozza S, Russo C, Liu S, Ye Y, Comerci M, Alfano B, Salvatore M, Haacke EM, Mancini M
* A Novel Multiparametric Approach to 3D Quantitative MRI of the Brain (605 views) (PDF 256 views)
Plosone (ISSN: 1932-6203, 1932-6203electronic, 1932-6203linking), 2015 Aug 18; 10(8): e0134963-e0134963.
Impact Factor: 3.057
View Export to BibTeX Export to EndNote
Conson M, Cella L, Pacelli R, Comerci M, Liuzzi R, Salvatore M, Quarantelli M
* Automated delineation of brain structures in patients undergoing radiotherapy for primary brain tumors: From atlas to dose-volume histograms (760 views) (PDF 368 views)
Radiother Oncol (ISSN: 0167-8140, 1879-0887, 0167-8140linking), 2014 Sep; 112(3): 326-331.
Impact Factor: 4.363
View Export to BibTeX Export to EndNote
D'Alterio C, Avallone A, Tatangelo F, Delrio P, Pecori B, Cella L, Pelella A, D'Armiento FP, Carlomagno C, Bianco F, Silvestro L, Pacelli R, Napolitano M, Iaffaioli RV, Scala S
* A prognostic model comprising pT stage, N status, and the chemokine receptors CXCR4 and CXCR7 powerfully predicts outcome in neoadjuvant resistant rectal cancer patients (385 views)
Int J Cancer (ISSN: 0020-7136), 2014 Jul 15; 135(2): 379-390.
Impact Factor: 5.085
View Export to BibTeX Export to EndNote
Murino L, Granata D, Carfora MF, Selvan SE, Alfano B, Amato U, Larobina M
* Evaluation of supervised methods for the classification of major tissues and subcortical structures in multispectral brain magnetic resonance images (441 views) (PDF 222 views)
Comput Med Imag Grap (ISSN: 0895-6111), 2014 Jul; 38(5): 337-347.
Impact Factor: 1.218
View Export to BibTeX Export to EndNote
Iodice D, Di Donato O, Liccardo I, Lamanna L, Segreto S, Salvatore M, Imbriaco M
* Prevalence of extramammary findings on breast MRI: a large retrospective single-centre study (328 views)
Radiol Med (ISSN: 1826-6983, 0033-8362, 1826-6983electronic), 2013 Oct; 118(7): 1109-1118.
Impact Factor: 1.368
View Export to BibTeX Export to EndNote
Mancini M, Greco A, Salvatore G, Liuzzi R, Di Maro G, Vergara E, Chiappetta G, Pasquinelli R, Brunetti A, Salvatore M
* Imaging of thyroid tumor angiogenesis with microbubbles targeted to vascular endothelial growth factor receptor type 2 in mice (448 views)
Bmc Med Imaging (ISSN: 1471-2342, 1471-2342electronic), 2013 Sep 12; 13(1): 31-31.
Impact Factor: 0.983
View Export to BibTeX Export to EndNote
Comerci M, Elefante A, Strianese D, Senese R, Bonavolonta P, Alfano B, Bonavolonta B, Brunetti A
* Semiautomatic regional segmentation to measure orbital fat volumes in thyroid-associated ophthalmopathy. A validation study (463 views) (PDF 251 views)
Neuroradiol J (ISSN: 1971-4009, 1971-4009print, 1971-4009linking), 2013 Aug; 26(4): 373-379.
Impact Factor: 2.16
View Export to BibTeX Export to EndNote
Risitano AM, Imbriaco M, Marando L, Seneca E, Soscia E, Malcovati L, Iori AP, Pane F, Notaro R, Matarazzo M
* From perpetual haemosiderinuria to possible iron overload: iron redistribution in paroxysmal nocturnal haemoglobinuria patients on eculizumab by magnetic resonance imaging (325 views)
Br J Haematol (ISSN: 0007-1048, 0007-1048linking, 1365-2141electronic), 2012 Sep; 158(3): 415-418.
Impact Factor: 4.942
View Export to BibTeX Export to EndNote
Digilio G, Menchise V, Gianolio E, Catanzaro V, Carrera C, Napolitano R, Fedeli F, Aime S
* Exofacial protein thiols as a route for the internalization of Gd(III)-based complexes for magnetic resonance imaging cell labeling (440 views)
J Med Chem (ISSN: 0022-2623, 1520-4804, 0022-2623print), 2010 Jul 8; 53(13): 4877-4890.
Impact Factor: 5.207
View Export to BibTeX Export to EndNote
Digilio G, Catanzaro V, Fedeli F, Gianolio E, Menchise V, Napolitano R, Gringeri C, Aime S
* Targeting exofacial protein thiols with Gd-III complexes. An efficient procedure for MRI cell labelling (323 views)
Chem Commun (ISSN: 1359-7345, 1364-548x, 1364-548xelectronic), 2009 Feb 28; (8): 893-895.
Impact Factor: 5.504
View Export to BibTeX Export to EndNote
Tedeschi G, Dinacci D, Lavorgna L, Prinster A, Savettieri G, Quattrone A, Livrea P, Messina C, Reggio A, Servillo G, Bresciamorra V, Orefice G, Paciello M, Brunetti A, Paolillo A, Coniglio G, Bonavita S, Di Costanzo A, Bellacosa A, Valentino P, Quarantelli M, Patti F, Salemi G, Cammarata E, Simone I, Salvatore M, Bonavita V, Alfano B
* Correlation between fatigue and brain atrophy and lesion load in multiple sclerosis patients independent of disability (499 views) (PDF 237 views)
J Neurol Sci (ISSN: 0022-510x), 2007 Dec 15; 263(1-2): 15-19.
Impact Factor: 2.315
View Export to BibTeX Export to EndNote
Amato U, Larobina M, Antoniadis A, Alfano B
* Segmentation of magnetic resonance brain images through discriminant analysis (554 views) (PDF 239 views)
J Neurosci Methods (ISSN: 0165-0270, 0165-0270linking, 1872-678xelectronic), 2003 Dec 30; 131(1-2): 65-74.
Impact Factor: 1.777
View Export to BibTeX Export to EndNote
Quarantelli M, Larobina M, Volpe U, Amati G, Tedeschi E, Ciarmiello A, Brunetti A, Galderisi S, Alfano B
* Stereotaxy-based regional brain volumetry applied to segmented MRI: Validation and results in deficit and nondeficit schizophrenia (364 views) (PDF 205 views)
Neuroimage (ISSN: 1053-8119, 1053-8119linking), 2002 Sep; 17(1): 373-384.
Impact Factor: 5.624
View Export to BibTeX Export to EndNote
Alfano B, Quarantelli M, Brunetti A, Larobina M, Covelli EM, Tedeschi E, Salvatore M
Reproducibility of intracranial volume measurement by unsupervised multispectral brain segmentation (500 views) (PDF 592 views)
Magn Reson Med (ISSN: 0740-3194, 1522-2594electronic, 0740-3194linking), 1998 Mar; 39(3): 497-499.
Impact Factor: 2.962
View Export to BibTeX Export to EndNote
Alfano B, Brunetti A, Covelli EM, Quarantelli M, Panico M, Ciarmiello A, Salvatore M
Unsupervised, automated segmentation of the normal brain using a multispectral relaxometric magnetic resonance approach (494 views) (PDF 686 views)
Magn Reson Med (ISSN: 0740-3194, 1522-2594electronic, 0740-3194linking), 1997 Jan; 37(1): 84-93.
Impact Factor: 3.012
View Export to BibTeX Export to EndNote
Caraglia M, Tagliaferri P, Correale P, Genua G, Pinto A, Del Vecchio S, Esposito G, Bianco AR
Cytosine arabinoside increases the binding of 125I-labelled epidermal growth factor and 125I-transferrin and enhances the in vitro targeting of human tumour cells with anti-(growth factor receptor) mAb (225 views)
Cancer Immunol Immunother (ISSN: 0340-7004linking), 1993 Aug; 37 (3 ): 150-156.
Impact Factor: 4.293
View Export to BibTeX Export to EndNote
Alfano B, Brunetti A, Ciarmiello A, Salvatore M
Simultaneous display of multiple MR parameters with 'quantitative magnetic color imaging' (335 views) (PDF 639 views)
J Comput Assisted Tomogr (ISSN: 0363-8715), 1992 Jul; 16(4): 634-640.
Impact Factor: 1.263
View Export to BibTeX Export to EndNote
45 Records (45 excluding Abstracts).
Total impact factor: 129.462 (129.462 excluding Abstracts).
Total 5 year impact factor: 153.544 (153.544 excluding Abstracts).
Total impact factor: 129.462 (129.462 excluding Abstracts).
Total 5 year impact factor: 153.544 (153.544 excluding Abstracts).
233 views. Last view on Wednesday 28 September 2022, 12:36:15
ibb.cnr.it