Water Soluble Melanin Derivatives for Dynamic Contrast Enhanced Photoacoustic Imaging of Tumor Vasculature and Response to Antiangiogenic Therapy
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Water Soluble Melanin Derivatives for Dynamic Contrast Enhanced Photoacoustic Imaging of Tumor Vasculature and Response to Antiangiogenic Therapy (167 views visite)

Longo DL, Stefania R, Callari C, De Rose F, Rolle R, Conti L, Consolino L, Arena F, Aime S

Adv Healthc Mater (ISSN: 2192-2640, 2192-2640linking), 2016 Oct 26; N/D: N/D-N/D.



Paper type Tipo di articolo: Journal Article,

Impact factor: 5.11, 5-year impact factor Impact factor a 5 anni: 5.454

Url: https://www.scopus.com/inward/record.uri?eid=2-s2.0-84996540052&doi=10.1002%2fadhm.201600550&partnerID=40&md5=7379262e5d20af2cd3eb0a4a70f326d4

Keywords Parole chiave: Dynamic Contrast Enhanced, Melanin, Nanoparticles, Photoacoustic, Tumors,

Affiliations Affiliazioni:

*** IBB - CNR ***
Institute of Biostructure and Bioimaging (CNR) c/o Molecular Biotechnology Center, Via Nizza 52, 10126, Torino, Italy., Department of Molecular Biotechnology and Health Sciences, University of Torino, Via Nizza 52, 10126, Torino, Italy., Department of Molecular Biotechnology and Health Sciences, University of Torino, Via Nizza 52, 10126, Torino, Italy. silvio.aime@unito.it.,


References Riferimenti:

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A dynamic contrast enhanced (DCE) approach for tumor photoacoustic (PA) imaging is described. Novel water soluble melanin-based derivatives are synthesized that exhibit good PA properties, stability, safety and accumulation in tumor bearing mice. This melanin derivative is capable to characterize tumor vasculature and to monitor vessel permeability changes upon antiangiogenic treatment. DCE-PA imaging can assess functional response to cancer treatments.
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Impact factor a 5 anni totale: 194.737 (191.616 escludendo Abstract e Conferenze).







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